SLC35F5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)5.02368088
2COPI coating of Golgi vesicle (GO:0048205)5.02368088
3L-phenylalanine catabolic process (GO:0006559)4.40955746
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.40955746
5maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.31398824
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.26276704
7L-phenylalanine metabolic process (GO:0006558)4.26276704
8intestinal cholesterol absorption (GO:0030299)4.23840779
9protein retention in ER lumen (GO:0006621)4.04638065
10cell adhesion mediated by integrin (GO:0033627)3.86424378
11lysine metabolic process (GO:0006553)3.75991837
12lysine catabolic process (GO:0006554)3.75991837
13COPII vesicle coating (GO:0048208)3.74682474
14sulfur amino acid catabolic process (GO:0000098)3.74338630
15triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.64726609
16protein carboxylation (GO:0018214)3.61464669
17peptidyl-glutamic acid carboxylation (GO:0017187)3.61464669
18alpha-linolenic acid metabolic process (GO:0036109)3.51897953
194-hydroxyproline metabolic process (GO:0019471)3.46021303
20bundle of His cell to Purkinje myocyte communication (GO:0086069)3.43369896
21aromatic amino acid family catabolic process (GO:0009074)3.41819982
22glyoxylate metabolic process (GO:0046487)3.41468417
23desmosome organization (GO:0002934)3.40986424
24cysteine metabolic process (GO:0006534)3.40812937
25intestinal absorption (GO:0050892)3.36204590
26glucocorticoid biosynthetic process (GO:0006704)3.33495849
27fatty acid beta-oxidation (GO:0006635)3.33205495
28transcytosis (GO:0045056)3.31069220
29regulation of transforming growth factor beta2 production (GO:0032909)3.29022643
30exocrine pancreas development (GO:0031017)3.28484632
31homocysteine metabolic process (GO:0050667)3.26163762
32valine metabolic process (GO:0006573)3.19592357
33fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.18071692
34cellular ketone body metabolic process (GO:0046950)3.16902713
35fatty acid oxidation (GO:0019395)3.15438361
36high-density lipoprotein particle remodeling (GO:0034375)3.10921872
37lipid oxidation (GO:0034440)3.10295233
38regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.09017108
39reverse cholesterol transport (GO:0043691)3.08259237
40sequestering of extracellular ligand from receptor (GO:0035581)3.08225108
41retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.08064697
422-oxoglutarate metabolic process (GO:0006103)3.07868814
43amino-acid betaine metabolic process (GO:0006577)3.06868284
44activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.04769177
45fatty acid catabolic process (GO:0009062)3.04560460
46negative regulation of fibrinolysis (GO:0051918)3.03867808
47kynurenine metabolic process (GO:0070189)3.02236669
48regulation of protein activation cascade (GO:2000257)3.00671309
49regulation of cholesterol homeostasis (GO:2000188)2.96891084
50cellular modified amino acid catabolic process (GO:0042219)2.96828487
51negative regulation of protein activation cascade (GO:2000258)2.94716209
52regulation of triglyceride catabolic process (GO:0010896)2.94029115
53acylglycerol homeostasis (GO:0055090)2.92447737
54triglyceride homeostasis (GO:0070328)2.92447737
55bile acid biosynthetic process (GO:0006699)2.91101117
56aspartate family amino acid catabolic process (GO:0009068)2.89047746
57regulation of complement activation (GO:0030449)2.88619474
58plasma lipoprotein particle clearance (GO:0034381)2.88599477
59retina vasculature morphogenesis in camera-type eye (GO:0061299)2.88380184
60complement activation, alternative pathway (GO:0006957)2.88013489
61negative regulation of complement activation (GO:0045916)2.86892947
62regulation of fibrinolysis (GO:0051917)2.85731684
63very-low-density lipoprotein particle assembly (GO:0034379)2.85437178
64short-chain fatty acid metabolic process (GO:0046459)2.85007762
65chondrocyte proliferation (GO:0035988)2.84915362
66phospholipid homeostasis (GO:0055091)2.83938024
67positive regulation of nuclease activity (GO:0032075)2.83286341
68monocarboxylic acid catabolic process (GO:0072329)2.81509049
69plasma lipoprotein particle remodeling (GO:0034369)2.80802221
70protein-lipid complex remodeling (GO:0034368)2.80802221
71macromolecular complex remodeling (GO:0034367)2.80802221
72fatty acid transmembrane transport (GO:1902001)2.79365048
73tricarboxylic acid metabolic process (GO:0072350)2.78699705
74macroautophagy (GO:0016236)2.78612683
75regulation of cholesterol esterification (GO:0010872)2.76505360
76hormone catabolic process (GO:0042447)2.75788637
77tryptophan metabolic process (GO:0006568)2.75135594
78carnitine metabolic process (GO:0009437)2.74912570
79phospholipid efflux (GO:0033700)2.74768280
80endocardial cushion development (GO:0003197)2.74236514
81branched-chain amino acid catabolic process (GO:0009083)2.74197690
82lipoprotein metabolic process (GO:0042157)2.73218274
83UDP-N-acetylglucosamine metabolic process (GO:0006047)2.72546850
84bile acid and bile salt transport (GO:0015721)2.71639622
85endocrine pancreas development (GO:0031018)2.71366823
86endoplasmic reticulum unfolded protein response (GO:0030968)2.71244151
87bile acid metabolic process (GO:0008206)2.70212124
88ketone body metabolic process (GO:1902224)2.69857239
89positive regulation of fatty acid biosynthetic process (GO:0045723)2.67649077
90indole-containing compound catabolic process (GO:0042436)2.66980337
91indolalkylamine catabolic process (GO:0046218)2.66980337
92tryptophan catabolic process (GO:0006569)2.66980337
93positive regulation of hormone biosynthetic process (GO:0046886)2.66859960
94hemidesmosome assembly (GO:0031581)2.66628602
95cellular glucuronidation (GO:0052695)2.66613763
96positive regulation of glycolytic process (GO:0045821)2.65607486
97branched-chain amino acid metabolic process (GO:0009081)2.64798767
98carnitine shuttle (GO:0006853)2.63834014
99positive regulation of fatty acid beta-oxidation (GO:0032000)2.63683638
100cellular response to unfolded protein (GO:0034620)2.63565302
101ER-nucleus signaling pathway (GO:0006984)2.62385531
102drug transmembrane transport (GO:0006855)2.59791245
103positive regulation of fatty acid oxidation (GO:0046321)2.59677313
104cholesterol efflux (GO:0033344)2.57802105
105coenzyme catabolic process (GO:0009109)2.57801637
106urea cycle (GO:0000050)2.57741898
107urea metabolic process (GO:0019627)2.57741898
108tyrosine metabolic process (GO:0006570)2.57218040
109Leydig cell differentiation (GO:0033327)2.57085006
110response to lipoprotein particle (GO:0055094)2.56130496
111fibrinolysis (GO:0042730)2.55993718
112negative regulation of fatty acid transport (GO:2000192)2.55464222
113iron ion import (GO:0097286)2.54946222
114alpha-amino acid catabolic process (GO:1901606)2.51227456
115peptide hormone processing (GO:0016486)2.51190236
116cellular amino acid catabolic process (GO:0009063)2.51107735
117sterol homeostasis (GO:0055092)2.50932006
118cholesterol homeostasis (GO:0042632)2.50788728
119regulation of nuclease activity (GO:0032069)2.50551540
120collagen fibril organization (GO:0030199)2.50301667
121glucocorticoid metabolic process (GO:0008211)2.50077925
122androgen biosynthetic process (GO:0006702)2.49509701
123glomerular visceral epithelial cell development (GO:0072015)2.49270397
124positive regulation of glycoprotein biosynthetic process (GO:0010560)2.48698162
125C21-steroid hormone biosynthetic process (GO:0006700)2.47970610
126embryonic foregut morphogenesis (GO:0048617)2.46432954
127progesterone metabolic process (GO:0042448)2.44708612
128keratan sulfate catabolic process (GO:0042340)2.43423430
129glomerular basement membrane development (GO:0032836)2.43416313
130regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.42879504
131skin morphogenesis (GO:0043589)2.42024276
132smooth muscle tissue development (GO:0048745)2.41663967
133response to follicle-stimulating hormone (GO:0032354)2.41250345
134substrate-dependent cell migration (GO:0006929)2.40966522
135protein hydroxylation (GO:0018126)2.40829239
136regulation of hippo signaling (GO:0035330)2.39737889
137negative regulation of keratinocyte proliferation (GO:0010839)2.39636944
138regulation of apoptotic cell clearance (GO:2000425)2.39417502
139fibroblast migration (GO:0010761)2.36576164
140lipid translocation (GO:0034204)2.34518712
141phospholipid translocation (GO:0045332)2.34518712
142cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.33098508
143intestinal epithelial cell development (GO:0060576)2.33058181
144positive regulation of hormone metabolic process (GO:0032352)2.33002905
145negative regulation of protein localization to cell surface (GO:2000009)2.29546657
146C21-steroid hormone metabolic process (GO:0008207)2.29141421
147regulation of steroid hormone biosynthetic process (GO:0090030)2.28638075
148anterior/posterior axis specification, embryo (GO:0008595)2.26896948
149regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.25943224
150regulation of transforming growth factor beta1 production (GO:0032908)2.24404427
151regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.23901670
152sphingosine metabolic process (GO:0006670)2.23303644
153Golgi to endosome transport (GO:0006895)2.23047725
154substrate adhesion-dependent cell spreading (GO:0034446)2.22730670
155intracellular lipid transport (GO:0032365)2.22709080
156flavonoid metabolic process (GO:0009812)2.21322849
157endodermal cell differentiation (GO:0035987)2.20932897
158androgen metabolic process (GO:0008209)2.20686323
159glomerular epithelial cell development (GO:0072310)2.20490774
160positive regulation of glycoprotein metabolic process (GO:1903020)2.20391464
161cellular response to ethanol (GO:0071361)2.19997543
162positive regulation of transforming growth factor beta production (GO:0071636)2.19683857
163regulation of transforming growth factor beta production (GO:0071634)2.19321587
164sphingomyelin metabolic process (GO:0006684)2.17982447
165wound healing, spreading of epidermal cells (GO:0035313)2.14891712
166extracellular regulation of signal transduction (GO:1900115)2.14520056
167extracellular negative regulation of signal transduction (GO:1900116)2.14520056
168oligosaccharide catabolic process (GO:0009313)2.13780052
169sterol transport (GO:0015918)2.13771508
170cholesterol transport (GO:0030301)2.13771508
171lung lobe morphogenesis (GO:0060463)2.13722209
172sphingoid metabolic process (GO:0046519)2.13673868
173glucuronate metabolic process (GO:0019585)2.12734820
174uronic acid metabolic process (GO:0006063)2.12734820
175endocrine hormone secretion (GO:0060986)2.12426619
176plasma lipoprotein particle assembly (GO:0034377)2.10763954
177regulation of keratinocyte proliferation (GO:0010837)2.09406859
178protein targeting to vacuole (GO:0006623)2.09185128
179protein targeting to lysosome (GO:0006622)2.09185128
180establishment of protein localization to vacuole (GO:0072666)2.09185128
181mesodermal cell differentiation (GO:0048333)2.08526189
182regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.07618858

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.84971519
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.03276351
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.46357721
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.30194662
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.21130738
6TP63_17297297_ChIP-ChIP_HaCaT_Human3.53825649
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.29050859
8TRIM28_21343339_ChIP-Seq_HEK293_Human3.02391491
9CLOCK_20551151_ChIP-Seq_293T_Human2.97230587
10CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.94687341
11EGR1_23403033_ChIP-Seq_LIVER_Mouse2.83044652
12NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.82328950
13RARG_19884340_ChIP-ChIP_MEFs_Mouse2.56364091
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.48232020
15SMAD_19615063_ChIP-ChIP_OVARY_Human2.38724357
16CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.33800329
17ESR1_21235772_ChIP-Seq_MCF-7_Human2.32268969
18GATA1_22025678_ChIP-Seq_K562_Human2.31233662
19POU3F2_20337985_ChIP-ChIP_501MEL_Human2.28949634
20SALL1_21062744_ChIP-ChIP_HESCs_Human2.28155081
21GBX2_23144817_ChIP-Seq_PC3_Human2.09768066
22ESR2_21235772_ChIP-Seq_MCF-7_Human2.06786576
23* SOX2_27498859_Chip-Seq_STOMACH_Mouse2.02220166
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.96361318
25FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.91472706
26TP53_16413492_ChIP-PET_HCT116_Human1.83557868
27TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.79957319
28RBPJ_22232070_ChIP-Seq_NCS_Mouse1.79033719
29SOX2_20726797_ChIP-Seq_SW620_Human1.73168173
30* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.72936819
31STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.71122463
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.69294924
33TP53_18474530_ChIP-ChIP_U2OS_Human1.67883772
34HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.67093887
35* BRD4_25478319_ChIP-Seq_HGPS_Human1.66832090
36* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65664990
37SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.62399404
38EP300_21415370_ChIP-Seq_HL-1_Mouse1.61776499
39GATA4_25053715_ChIP-Seq_YYC3_Human1.61163986
40TAF15_26573619_Chip-Seq_HEK293_Human1.58540605
41OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57097901
42FOXO3_23340844_ChIP-Seq_DLD1_Human1.56875531
43* SMAD4_21799915_ChIP-Seq_A2780_Human1.56580401
44FOXA2_19822575_ChIP-Seq_HepG2_Human1.55674695
45ARNT_22903824_ChIP-Seq_MCF-7_Human1.54057211
46* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.53982454
47ESR1_20079471_ChIP-ChIP_T-47D_Human1.53483297
48PPAR_26484153_Chip-Seq_NCI-H1993_Human1.53442095
49SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53174312
50NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.52865012
51NRF2_20460467_ChIP-Seq_MEFs_Mouse1.52865012
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.52575184
53P300_19829295_ChIP-Seq_ESCs_Human1.51579610
54GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51083014
55CDX2_19796622_ChIP-Seq_MESCs_Mouse1.50701526
56PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.50447532
57SALL4_18804426_ChIP-ChIP_XEN_Mouse1.45861867
58ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.44686924
59TBX20_22328084_ChIP-Seq_HEART_Mouse1.43053932
60TBX20_22080862_ChIP-Seq_HEART_Mouse1.43053932
61IGF1R_20145208_ChIP-Seq_DFB_Human1.42367560
62* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.40518618
63BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.39787582
64* CDX2_22108803_ChIP-Seq_LS180_Human1.39341397
65* EZH2_27294783_Chip-Seq_NPCs_Mouse1.38583972
66* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.37540417
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.37335740
68FUS_26573619_Chip-Seq_HEK293_Human1.36941295
69CJUN_26792858_Chip-Seq_BT549_Human1.36548394
70* NANOG_18555785_Chip-Seq_ESCs_Mouse1.35781353
71STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.35523918
72TCF4_18268006_ChIP-ChIP_LS174T_Human1.35042314
73TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.34697643
74STAT3_23295773_ChIP-Seq_U87_Human1.33304963
75PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.32782650
76AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.32584767
77BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.32350171
78CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.32219604
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.31939389
80ZNF263_19887448_ChIP-Seq_K562_Human1.31030120
81NR3C1_21868756_ChIP-Seq_MCF10A_Human1.30951884
82CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.30270161
83ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.29974851
84* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.29575449
85* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.28426633
86SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26903597
87TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.26656878
88ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.26529600
89FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.26402564
90ZNF274_21170338_ChIP-Seq_K562_Hela1.22759513
91Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.22604046
92CTNNB1_20460455_ChIP-Seq_HCT116_Human1.21737517
93* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20152287
94GATA6_25053715_ChIP-Seq_YYC3_Human1.19536047
95AR_25329375_ChIP-Seq_VCAP_Human1.19296416
96ER_23166858_ChIP-Seq_MCF-7_Human1.17795152
97NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.16717660
98GATA3_24758297_ChIP-Seq_MCF-7_Human1.15964886
99* E2F1_18555785_Chip-Seq_ESCs_Mouse1.15356461
100SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.14261596
101* NFE2_27457419_Chip-Seq_LIVER_Mouse1.14110535
102GATA2_21666600_ChIP-Seq_HMVEC_Human1.13301166
103TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.13185507
104ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.11506071
105* CMYC_18555785_Chip-Seq_ESCs_Mouse1.11316138
106* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10874456
107CDX2_20551321_ChIP-Seq_CACO-2_Human1.10647785
108* P53_22387025_ChIP-Seq_ESCs_Mouse1.09092766
109HIF1A_21447827_ChIP-Seq_MCF-7_Human1.07536191
110FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.07501312
111TCF4_23295773_ChIP-Seq_U87_Human1.07500595
112SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.07273480
113TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06686726
114UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05734007
115* CRX_20693478_ChIP-Seq_RETINA_Mouse1.05483277
116* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05211676
117PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.04798788
118CBP_20019798_ChIP-Seq_JUKART_Human1.03760772
119IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.03760772
120KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.03399946
121SOX9_24532713_ChIP-Seq_HFSC_Mouse1.03239198
122P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02528817
123HNF4A_19822575_ChIP-Seq_HepG2_Human1.01567435
124FOXA1_25552417_ChIP-Seq_VCAP_Human1.01445615
125* TP63_23658742_ChIP-Seq_EP156T_Human0.95269821
126ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.95010780
127BCAT_22108803_ChIP-Seq_LS180_Human0.92983093
128THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.92971591
129WT1_19549856_ChIP-ChIP_CCG9911_Human0.92398555
130PIAS1_25552417_ChIP-Seq_VCAP_Human0.91427600
131SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.91353428
132SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.91353428
133RACK7_27058665_Chip-Seq_MCF-7_Human0.91266097
134* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.88910315
135KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.87631426
136* ATF3_27146783_Chip-Seq_COLON_Human0.86283112
137RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.81782927
138RUNX1_27514584_Chip-Seq_MCF-7_Human0.81673101
139PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.79459893
140CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.77655465
141FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.77312125
142JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.76986680
143JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.74343331
144NR3C1_23031785_ChIP-Seq_PC12_Mouse0.74129007
145* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.71989192
146GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.71081565
147* MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.70669361
148AHR_22903824_ChIP-Seq_MCF-7_Human0.70122351
149ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.69717597
150GATA1_19941826_ChIP-Seq_K562_Human0.68692687
151NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.66328272
152HTT_18923047_ChIP-ChIP_STHdh_Human0.65788994
153CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.65522326
154RXR_22108803_ChIP-Seq_LS180_Human0.64874443
155* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.64078408
156AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.63937558

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.90752611
2MP0005360_urolithiasis4.07344434
3MP0005365_abnormal_bile_salt4.06503066
4MP0005085_abnormal_gallbladder_physiolo3.87119934
5MP0003950_abnormal_plasma_membrane3.82207934
6MP0001666_abnormal_nutrient_absorption2.99351829
7MP0003195_calcinosis2.99253782
8MP0003941_abnormal_skin_development2.83245965
9MP0003252_abnormal_bile_duct2.82910600
10MP0002837_dystrophic_cardiac_calcinosis2.74430716
11MP0008875_abnormal_xenobiotic_pharmacok2.66635063
12MP0005083_abnormal_biliary_tract2.55177873
13MP0003705_abnormal_hypodermis_morpholog2.52400195
14MP0003806_abnormal_nucleotide_metabolis2.31768375
15MP0009840_abnormal_foam_cell2.29135493
16MP0010352_gastrointestinal_tract_polyps2.27029676
17MP0008438_abnormal_cutaneous_collagen2.24351665
18MP0000569_abnormal_digit_pigmentation2.16492048
19MP0010329_abnormal_lipoprotein_level2.10906414
20MP0010678_abnormal_skin_adnexa2.00161627
21MP0005220_abnormal_exocrine_pancreas1.89358715
22MP0006054_spinal_hemorrhage1.87561666
23MP0005332_abnormal_amino_acid1.84321408
24MP0009780_abnormal_chondrocyte_physiolo1.81081771
25MP0009384_cardiac_valve_regurgitation1.78562514
26MP0005275_abnormal_skin_tensile1.78235539
27MP0002877_abnormal_melanocyte_morpholog1.78231700
28MP0002138_abnormal_hepatobiliary_system1.77549119
29MP0005257_abnormal_intraocular_pressure1.73359099
30MP0004043_abnormal_pH_regulation1.65701882
31MP0005171_absent_coat_pigmentation1.62832440
32MP0000383_abnormal_hair_follicle1.61235925
33MP0010234_abnormal_vibrissa_follicle1.60729099
34MP0004084_abnormal_cardiac_muscle1.60670209
35MP0003868_abnormal_feces_composition1.57858428
36MP0002118_abnormal_lipid_homeostasis1.56575991
37MP0009643_abnormal_urine_homeostasis1.56103883
38MP0000013_abnormal_adipose_tissue1.50162161
39MP0003191_abnormal_cellular_cholesterol1.47919398
40MP0004130_abnormal_muscle_cell1.40575808
41MP0004264_abnormal_extraembryonic_tissu1.39314749
42MP0000609_abnormal_liver_physiology1.39231550
43MP0010368_abnormal_lymphatic_system1.38526156
44MP0004272_abnormal_basement_membrane1.37977916
45MP0001661_extended_life_span1.36020942
46MP0005319_abnormal_enzyme/_coenzyme1.33720721
47MP0003300_gastrointestinal_ulcer1.32870301
48MP0001299_abnormal_eye_distance/1.30624851
49MP0003890_abnormal_embryonic-extraembry1.29200262
50MP0000427_abnormal_hair_cycle1.28970456
51MP0002909_abnormal_adrenal_gland1.26652542
52MP0001944_abnormal_pancreas_morphology1.24930039
53MP0004484_altered_response_of1.24896673
54MP0005058_abnormal_lysosome_morphology1.24590407
55MP0002693_abnormal_pancreas_physiology1.23851109
56MP0002078_abnormal_glucose_homeostasis1.23084027
57MP0003091_abnormal_cell_migration1.21463275
58MP0005023_abnormal_wound_healing1.21093998
59MP0004019_abnormal_vitamin_homeostasis1.20192561
60MP0010386_abnormal_urinary_bladder1.20177926
61MP0005084_abnormal_gallbladder_morpholo1.18078416
62MP0004036_abnormal_muscle_relaxation1.16848361
63MP0002896_abnormal_bone_mineralization1.14897901
64MP0001756_abnormal_urination1.13325293
65MP0005330_cardiomyopathy1.13273410
66MP0005503_abnormal_tendon_morphology1.08948514
67MP0003566_abnormal_cell_adhesion1.05451716
68MP0003283_abnormal_digestive_organ1.04613833
69MP0002254_reproductive_system_inflammat1.03846531
70MP0008004_abnormal_stomach_pH1.03783128
71MP0005409_darkened_coat_color1.03556207
72MP0002972_abnormal_cardiac_muscle1.03164252
73MP0001915_intracranial_hemorrhage1.02071857
74MP0004215_abnormal_myocardial_fiber1.00105650
75MP0005164_abnormal_response_to0.99317194
76MP0002060_abnormal_skin_morphology0.99155856
77MP0000003_abnormal_adipose_tissue0.99009323
78MP0002295_abnormal_pulmonary_circulatio0.98790336
79MP0004134_abnormal_chest_morphology0.98306634
80MP0005666_abnormal_adipose_tissue0.96761413
81MP0000639_abnormal_adrenal_gland0.95539252
82MP0003279_aneurysm0.94644675
83MP0005197_abnormal_uvea_morphology0.94589971
84MP0000751_myopathy0.94372244
85MP0000767_abnormal_smooth_muscle0.91715443
86MP0005595_abnormal_vascular_smooth0.91521746
87MP0000371_diluted_coat_color0.91150239
88MP0005248_abnormal_Harderian_gland0.90229381
89MP0000647_abnormal_sebaceous_gland0.89974713
90MP0009697_abnormal_copulation0.89711430
91MP0002234_abnormal_pharynx_morphology0.89430096
92MP0005375_adipose_tissue_phenotype0.88984551
93MP0000230_abnormal_systemic_arterial0.86874007
94MP0003045_fibrosis0.86192567
95MP0004233_abnormal_muscle_weight0.85834245
96MP0002938_white_spotting0.84917311
97MP0000538_abnormal_urinary_bladder0.84764009
98MP0001544_abnormal_cardiovascular_syste0.84526931
99MP0005385_cardiovascular_system_phenoty0.84526931
100MP0004087_abnormal_muscle_fiber0.84261319
101MP0004185_abnormal_adipocyte_glucose0.84158765
102MP0005670_abnormal_white_adipose0.84062619
103MP0002876_abnormal_thyroid_physiology0.84044517
104MP0002108_abnormal_muscle_morphology0.83745508
105MP0000750_abnormal_muscle_regeneration0.83434049
106MP0006138_congestive_heart_failure0.83100176
107MP0005636_abnormal_mineral_homeostasis0.82912200
108MP0008775_abnormal_heart_ventricle0.82353015
109MP0005395_other_phenotype0.82028810
110MP0001879_abnormal_lymphatic_vessel0.80623196
111MP0002796_impaired_skin_barrier0.80233497
112MP0002160_abnormal_reproductive_system0.79973621
113MP0005165_increased_susceptibility_to0.79103533
114MP0010630_abnormal_cardiac_muscle0.78760807
115MP0003937_abnormal_limbs/digits/tail_de0.78679342
116MP0003183_abnormal_peptide_metabolism0.78005573
117MP0002269_muscular_atrophy0.77112393
118MP0001765_abnormal_ion_homeostasis0.76768534
119MP0000749_muscle_degeneration0.76022220
120MP0005167_abnormal_blood-brain_barrier0.75667923
121MP0000534_abnormal_ureter_morphology0.75454628
122MP0005620_abnormal_muscle_contractility0.75446868
123MP0005584_abnormal_enzyme/coenzyme_acti0.74714576
124MP0005408_hypopigmentation0.74129360
125MP0000462_abnormal_digestive_system0.73970886
126MP0000598_abnormal_liver_morphology0.73380879
127MP0000604_amyloidosis0.72628206
128MP0001958_emphysema0.71512117
129MP0002928_abnormal_bile_duct0.69689791
130MP0002115_abnormal_skeleton_extremities0.69286410
131MP0002971_abnormal_brown_adipose0.68796497
132MP0001324_abnormal_eye_pigmentation0.67219986
133MP0003186_abnormal_redox_activity0.67060247
134MP0009642_abnormal_blood_homeostasis0.66022164
135MP0002332_abnormal_exercise_endurance0.64898315
136MP0005334_abnormal_fat_pad0.64370325
137MP0000516_abnormal_urinary_system0.63725795
138MP0005367_renal/urinary_system_phenotyp0.63725795
139MP0005448_abnormal_energy_balance0.63464235
140MP0002168_other_aberrant_phenotype0.63134363
141MP0003122_maternal_imprinting0.62935386
142MP0005508_abnormal_skeleton_morphology0.62847495
143MP0006036_abnormal_mitochondrial_physio0.62061839

Predicted human phenotypes

RankGene SetZ-score
1Hypoglycemic coma (HP:0001325)5.30742169
2Abnormality of aromatic amino acid family metabolism (HP:0004338)4.24134075
3Ketoacidosis (HP:0001993)4.19272145
4Intrahepatic cholestasis (HP:0001406)4.15874942
5Hyperinsulinemic hypoglycemia (HP:0000825)3.98096026
6Xanthomatosis (HP:0000991)3.95993384
7Right ventricular cardiomyopathy (HP:0011663)3.95267416
8Hypoglycemic seizures (HP:0002173)3.85953759
9Ketosis (HP:0001946)3.75285675
10Deep venous thrombosis (HP:0002625)3.73243161
11Mitral stenosis (HP:0001718)3.54333670
12Abnormality of the intrinsic pathway (HP:0010989)3.44506665
13Hyperglycemia (HP:0003074)3.36884520
14Abnormality of monocarboxylic acid metabolism (HP:0010996)3.33874092
15Aortic dissection (HP:0002647)3.31856864
16Aortic aneurysm (HP:0004942)3.31245421
17Abnormality of the common coagulation pathway (HP:0010990)3.25807524
18Symptomatic seizures (HP:0011145)3.17270267
19Vascular tortuosity (HP:0004948)3.12378506
20Arterial tortuosity (HP:0005116)3.06427107
21Generalized aminoaciduria (HP:0002909)3.04372657
22Fat malabsorption (HP:0002630)3.03984540
23Late onset (HP:0003584)3.03917602
24Follicular hyperkeratosis (HP:0007502)3.03696525
25Abnormality of fatty-acid metabolism (HP:0004359)2.96015923
26Hyperlipoproteinemia (HP:0010980)2.93747526
27Hypoalphalipoproteinemia (HP:0003233)2.93112807
28Gout (HP:0001997)2.89369067
29Hypobetalipoproteinemia (HP:0003563)2.85138121
30Prolonged partial thromboplastin time (HP:0003645)2.84705737
31Conjugated hyperbilirubinemia (HP:0002908)2.83841118
32Skin nodule (HP:0200036)2.83510494
33Hyperammonemia (HP:0001987)2.82380905
34Hypolipoproteinemia (HP:0010981)2.78992720
35Myoglobinuria (HP:0002913)2.77837813
36Complement deficiency (HP:0004431)2.75530544
37Hyperglycinuria (HP:0003108)2.75153331
38Epidermoid cyst (HP:0200040)2.72348123
39Abnormality of glutamine family amino acid metabolism (HP:0010902)2.70934205
40Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.67349735
41Abnormality of purine metabolism (HP:0004352)2.66541586
42Tetraparesis (HP:0002273)2.61658566
43Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.58835732
44Protuberant abdomen (HP:0001538)2.54475715
45Abnormality of endocrine pancreas physiology (HP:0012093)2.51326219
46Abnormality of the pancreatic islet cells (HP:0006476)2.51326219
47Abnormality of glycine metabolism (HP:0010895)2.46080009
48Abnormality of serine family amino acid metabolism (HP:0010894)2.46080009
49Mucopolysacchariduria (HP:0008155)2.44801940
50Urinary glycosaminoglycan excretion (HP:0003541)2.44801940
51Ventricular tachycardia (HP:0004756)2.41199947
52Ovoid vertebral bodies (HP:0003300)2.36637438
53Decreased circulating renin level (HP:0003351)2.36598662
54Dicarboxylic aciduria (HP:0003215)2.33729904
55Abnormality of dicarboxylic acid metabolism (HP:0010995)2.33729904
56Hyperglycinemia (HP:0002154)2.33661976
57Osteolytic defects of the phalanges of the hand (HP:0009771)2.31426968
58Osteolytic defects of the hand bones (HP:0009699)2.31426968
59Abnormality of carpal bone ossification (HP:0006257)2.30627207
60Insulin-resistant diabetes mellitus (HP:0000831)2.30388462
61Abnormality of sulfur amino acid metabolism (HP:0004339)2.30350964
62Flat acetabular roof (HP:0003180)2.29319084
63Abnormality of proline metabolism (HP:0010907)2.29182554
64Hydroxyprolinuria (HP:0003080)2.29182554
65Asymmetric septal hypertrophy (HP:0001670)2.28908686
66Bilateral sensorineural hearing impairment (HP:0008619)2.26258198
67Pancreatic islet-cell hyperplasia (HP:0004510)2.25169881
68Atrophic scars (HP:0001075)2.24257254
69Palpitations (HP:0001962)2.22005172
70Popliteal pterygium (HP:0009756)2.21731603
71Abdominal distention (HP:0003270)2.21427231
72Soft skin (HP:0000977)2.20048785
73Steatorrhea (HP:0002570)2.19990111
74Sudden death (HP:0001699)2.19888422
75Abnormal cartilage morphology (HP:0002763)2.19689471
76Hyporeflexia of lower limbs (HP:0002600)2.19530249
77Abnormality of polysaccharide metabolism (HP:0011012)2.17379420
78Abnormality of glycosaminoglycan metabolism (HP:0004371)2.17379420
79Abnormality of mucopolysaccharide metabolism (HP:0011020)2.17379420
80Papillary thyroid carcinoma (HP:0002895)2.14444963
81Cardiovascular calcification (HP:0011915)2.11604764
82Hypothermia (HP:0002045)2.09640036
83Dysostosis multiplex (HP:0000943)2.09557838
84Abnormality of aspartate family amino acid metabolism (HP:0010899)2.09067258
85Vascular calcification (HP:0004934)2.07646748
86Neonatal short-limb short stature (HP:0008921)2.04367592
87Abnormality of complement system (HP:0005339)2.04220098
88Hepatocellular carcinoma (HP:0001402)2.03802031
89Myocardial infarction (HP:0001658)2.03635216
90Wormian bones (HP:0002645)2.02938154
91Curly hair (HP:0002212)1.99762677
92Syncope (HP:0001279)1.99685181
93Absent frontal sinuses (HP:0002688)1.99363041
94Hematochezia (HP:0002573)1.99357049
95Esophageal varix (HP:0002040)1.98641435
96Protrusio acetabuli (HP:0003179)1.97670869
97Limited hip movement (HP:0008800)1.97422047
98Striae distensae (HP:0001065)1.96201549
99Metabolic acidosis (HP:0001942)1.95881542
100Exercise-induced muscle cramps (HP:0003710)1.95407901
101Insulin resistance (HP:0000855)1.95395556
102Asymmetry of the thorax (HP:0001555)1.94950942
103Increased purine levels (HP:0004368)1.93975385
104Hyperuricemia (HP:0002149)1.93975385
105Premature rupture of membranes (HP:0001788)1.92411531
106Abnormal pancreas size (HP:0012094)1.91569284
107Abnormality of the acetabulum (HP:0003170)1.91267683
108Type 1 muscle fiber predominance (HP:0003803)1.91027120
109Vacuolated lymphocytes (HP:0001922)1.90293819
110Alopecia of scalp (HP:0002293)1.89892074
111Large for gestational age (HP:0001520)1.88010866
112Joint hemorrhage (HP:0005261)1.87758891
113Hypercholesterolemia (HP:0003124)1.87382907
114Abnormality of urine glucose concentration (HP:0011016)1.87348647
115Glycosuria (HP:0003076)1.87348647
116Proximal tubulopathy (HP:0000114)1.87243900
117Abnormality of nucleobase metabolism (HP:0010932)1.86006124
118Abnormality of methionine metabolism (HP:0010901)1.84947996
119Abnormal hand bone ossification (HP:0010660)1.84687676
120Hyperbilirubinemia (HP:0002904)1.82615227
121Submucous cleft hard palate (HP:0000176)1.82568322
122Abnormality of the calf musculature (HP:0001430)1.82243473
123Hyperaldosteronism (HP:0000859)1.82094799
124Malnutrition (HP:0004395)1.79812235
125Cervical subluxation (HP:0003308)1.79156883
126Abnormality of the wing of the ilium (HP:0011867)1.78355516
127Pancreatitis (HP:0001733)1.78218719
128Abnormal biliary tract morphology (HP:0012440)1.77855819
129Abnormal foot bone ossification (HP:0010675)1.76993041
130Aneurysm (HP:0002617)1.75514344
131Increased connective tissue (HP:0009025)1.74192332
132Metaphyseal dysplasia (HP:0100255)1.74120244
133Abnormal tarsal ossification (HP:0008369)1.72909900
134Back pain (HP:0003418)1.72557220
135Abnormality of the ischium (HP:0003174)1.72522378
136Coarse hair (HP:0002208)1.71719987
137Hypoplastic ischia (HP:0003175)1.70308920
138Abnormal ossification of hand bones (HP:0005921)1.70275286
139Knee flexion contracture (HP:0006380)1.70038766
140Dilated cardiomyopathy (HP:0001644)1.68547317
141Abnormal gallbladder morphology (HP:0012437)1.68412142
142Tubular atrophy (HP:0000092)1.67413402
143Overgrowth (HP:0001548)1.66886840
144Short nail (HP:0001799)1.66682840
145Acanthocytosis (HP:0001927)1.65741426
146Abnormality of secondary sexual hair (HP:0009888)1.64332477
147Abnormality of the axillary hair (HP:0100134)1.64332477
148Ankle contracture (HP:0006466)1.64285134
149Abnormality of the renal cortex (HP:0011035)1.63160118
150Round ear (HP:0100830)1.62916549
151Abnormality of the nasal septum (HP:0000419)1.60623683
152Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.60097053
153Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.60033818
154Aplasia of the musculature (HP:0100854)1.59726680
155Vertebral compression fractures (HP:0002953)1.59131528
156Nemaline bodies (HP:0003798)1.58817194
157Spondylolisthesis (HP:0003302)1.58222893
158Thyroid carcinoma (HP:0002890)1.55736407
159Thickened calvaria (HP:0002684)1.55515200
160Mildly elevated creatine phosphokinase (HP:0008180)1.55062389
161Delayed closure of the anterior fontanelle (HP:0001476)1.54998156
162Congenital sensorineural hearing impairment (HP:0008527)1.54117607
163Pulmonic stenosis (HP:0001642)1.53560620
164Disproportionate short-trunk short stature (HP:0003521)1.53455211
165Mitral valve prolapse (HP:0001634)1.53331271
166Potter facies (HP:0002009)1.52703422
167Facial shape deformation (HP:0011334)1.52703422

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN13.91619119
2INSRR3.82431178
3BCKDK3.75923952
4TRIB33.29711485
5FRK2.93872345
6PKN22.65782845
7LATS12.62672057
8ACVR1B2.48666043
9STK392.32487071
10TTN2.22231067
11SIK12.13418312
12TAOK32.07258242
13FLT32.02664808
14PTK61.93544827
15MAP3K21.91791425
16PDGFRA1.87375255
17LMTK21.86199659
18FGFR41.84648359
19MAP3K31.77758672
20BRSK21.76449107
21EPHA31.76132338
22MST1R1.72208128
23MET1.69324719
24BCR1.68949541
25FER1.65110239
26EIF2AK31.65011320
27MAPK151.52766310
28MYLK1.52741359
29WNK41.44573995
30PTK21.44278687
31WNK31.43868793
32EPHA21.35698784
33PIK3CG1.33482169
34IRAK31.33478512
35MAP2K21.29435810
36DDR21.25355444
37GRK11.24323831
38PIK3CA1.21248264
39LIMK11.21045292
40BMPR1B1.19988117
41EPHB11.19524315
42CASK1.19223229
43RIPK11.17346042
44PAK31.10916904
45PDK31.07296585
46PDK41.07296585
47TIE11.07047440
48TGFBR21.05725829
49PDK21.02338838
50EPHB21.01853762
51NLK1.01698707
52PASK1.01494357
53MAP2K11.01255140
54MAP4K21.01132075
55STK38L0.99171880
56PRKD30.97003314
57FGFR10.96985372
58FGFR20.96520758
59NEK90.96394694
60MAP3K120.95028616
61OXSR10.91038745
62MAP3K10.90334054
63PHKG10.87694764
64PHKG20.87694764
65ERBB40.87058073
66MAPKAPK30.86193760
67STK380.85788760
68OBSCN0.85498109
69STK240.82216673
70MAP3K40.81069678
71RET0.78419118
72MELK0.76296839
73PRKG20.75718590
74PRKD10.75126380
75SGK20.74967986
76TNIK0.73397066
77TRPM70.71005881
78JAK10.70381740
79NTRK10.69142658
80SGK30.68823192
81SCYL20.67470989
82PRKAA20.67081112
83ADRBK20.65084249
84ABL20.64390920
85DMPK0.63085677
86DYRK1B0.62664317
87TRIM280.62563821
88JAK20.62203868
89PLK20.61549703
90LRRK20.61155431
91PDGFRB0.61149291
92KDR0.60616071
93TYK20.60005339
94IRAK10.58890943
95CSNK1A1L0.58436657
96PRKAA10.57697179
97STK30.55748493
98GSK3A0.55404271
99MST40.54786219
100HIPK20.54052140
101FGFR30.52901186
102PAK40.52900710
103CAMK2D0.52532284
104GRK70.51638980
105TBK10.51615820
106MAP2K30.51050256
107TESK10.50034138
108PAK20.49240175
109PRKCE0.48738229
110PDPK10.47405481
111MUSK0.46940491
112BMPR20.46468081
113AKT30.46228579
114ERBB30.45824370
115NUAK10.44956669
116MTOR0.44268386
117TGFBR10.44159732
118CDC42BPA0.43965415
119IGF1R0.43847982
120MAPK110.43835371
121CSNK1G10.43112017
122PBK0.41594093
123PRKACG0.40578095
124MAP3K50.39918033
125RPS6KB10.39661593
126MAP3K70.39386226
127ROCK10.39327923
128ADRBK10.38921048
129MAP2K70.38867554
130KSR20.37667352
131PRKCH0.36579596
132ABL10.36246254
133EIF2AK10.35384227
134ERBB20.33176525
135PINK10.32752731
136CAMK1D0.32435898
137CAMKK20.32191205
138LATS20.31802961
139SGK2230.31365690
140SGK4940.31365690
141CDK60.30919233
142CHUK0.28089829
143CDK90.27713589

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.42183667
2Fatty acid degradation_Homo sapiens_hsa000712.81559687
3Sulfur metabolism_Homo sapiens_hsa009202.73508771
4Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.70031222
5Primary bile acid biosynthesis_Homo sapiens_hsa001202.54834645
6Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.42323854
7Tryptophan metabolism_Homo sapiens_hsa003802.42247472
8Propanoate metabolism_Homo sapiens_hsa006402.19029872
9Nitrogen metabolism_Homo sapiens_hsa009102.17559009
10Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.12665727
11Fat digestion and absorption_Homo sapiens_hsa049752.04181189
12Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.02280546
13Fatty acid metabolism_Homo sapiens_hsa012122.00268716
14Butanoate metabolism_Homo sapiens_hsa006501.93309909
15Arginine biosynthesis_Homo sapiens_hsa002201.91224677
16Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.86537507
17Sphingolipid metabolism_Homo sapiens_hsa006001.80364470
18Complement and coagulation cascades_Homo sapiens_hsa046101.77704573
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.74504248
20PPAR signaling pathway_Homo sapiens_hsa033201.66662435
21Starch and sucrose metabolism_Homo sapiens_hsa005001.66530609
22Pentose and glucuronate interconversions_Homo sapiens_hsa000401.64083532
23Peroxisome_Homo sapiens_hsa041461.62689143
24Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.62010903
25Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.59711890
26Histidine metabolism_Homo sapiens_hsa003401.57431504
27Protein export_Homo sapiens_hsa030601.52164690
28Selenocompound metabolism_Homo sapiens_hsa004501.51487301
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.38815716
30Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.36934688
31beta-Alanine metabolism_Homo sapiens_hsa004101.34263823
32Caffeine metabolism_Homo sapiens_hsa002321.30968516
33Chemical carcinogenesis_Homo sapiens_hsa052041.30429286
34Bile secretion_Homo sapiens_hsa049761.27736646
35Fatty acid elongation_Homo sapiens_hsa000621.27527790
36Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.27399267
37Circadian rhythm_Homo sapiens_hsa047101.26920803
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.26620172
39Folate biosynthesis_Homo sapiens_hsa007901.25508593
40Phenylalanine metabolism_Homo sapiens_hsa003601.23440430
41Pyruvate metabolism_Homo sapiens_hsa006201.23216520
42Vitamin B6 metabolism_Homo sapiens_hsa007501.20744072
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.13109779
44Carbon metabolism_Homo sapiens_hsa012001.11502217
45Protein digestion and absorption_Homo sapiens_hsa049741.06497465
46Steroid biosynthesis_Homo sapiens_hsa001001.03522257
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.01002688
48Arginine and proline metabolism_Homo sapiens_hsa003301.00477888
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.00270533
50Ovarian steroidogenesis_Homo sapiens_hsa049130.99218009
51ABC transporters_Homo sapiens_hsa020100.97856982
52Vitamin digestion and absorption_Homo sapiens_hsa049770.95505317
53Proteoglycans in cancer_Homo sapiens_hsa052050.93399122
54Steroid hormone biosynthesis_Homo sapiens_hsa001400.92667681
55TGF-beta signaling pathway_Homo sapiens_hsa043500.92635416
56Retinol metabolism_Homo sapiens_hsa008300.91313177
57Tyrosine metabolism_Homo sapiens_hsa003500.90954859
58Staphylococcus aureus infection_Homo sapiens_hsa051500.90499451
59Pancreatic secretion_Homo sapiens_hsa049720.88875335
60Galactose metabolism_Homo sapiens_hsa000520.88023598
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.87147689
62Insulin resistance_Homo sapiens_hsa049310.87132308
63Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.87073841
64Tight junction_Homo sapiens_hsa045300.85803492
65Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80380802
66Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.80149472
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.77704850
68Lysosome_Homo sapiens_hsa041420.77650104
69Glycerolipid metabolism_Homo sapiens_hsa005610.77385204
70Lysine degradation_Homo sapiens_hsa003100.77283006
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.76669645
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73892764
73Glycosaminoglycan degradation_Homo sapiens_hsa005310.73472739
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.72771787
75Ether lipid metabolism_Homo sapiens_hsa005650.70692073
76Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69443469
77Small cell lung cancer_Homo sapiens_hsa052220.68911764
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66852603
79Hippo signaling pathway_Homo sapiens_hsa043900.65826835
80PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62538095
81Other glycan degradation_Homo sapiens_hsa005110.62040608
82Dorso-ventral axis formation_Homo sapiens_hsa043200.61860630
83Renin-angiotensin system_Homo sapiens_hsa046140.61565231
84ECM-receptor interaction_Homo sapiens_hsa045120.61009225
85Biosynthesis of amino acids_Homo sapiens_hsa012300.58894255
86Glutathione metabolism_Homo sapiens_hsa004800.57356371
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.56449923
88Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55920758
89Linoleic acid metabolism_Homo sapiens_hsa005910.55606132
90Mineral absorption_Homo sapiens_hsa049780.54503088
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.53190249
92Fructose and mannose metabolism_Homo sapiens_hsa000510.48940471
93Melanoma_Homo sapiens_hsa052180.47892826
94Vibrio cholerae infection_Homo sapiens_hsa051100.45585887
95N-Glycan biosynthesis_Homo sapiens_hsa005100.45530355
96Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45185362
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44901849
98Glucagon signaling pathway_Homo sapiens_hsa049220.44825636
99Cyanoamino acid metabolism_Homo sapiens_hsa004600.44509194
100Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.44312131
101Inositol phosphate metabolism_Homo sapiens_hsa005620.44133565
102Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.43819224
103Dilated cardiomyopathy_Homo sapiens_hsa054140.42839386
104Insulin secretion_Homo sapiens_hsa049110.41981869
105Type II diabetes mellitus_Homo sapiens_hsa049300.41807285
106Prion diseases_Homo sapiens_hsa050200.41567948
107mTOR signaling pathway_Homo sapiens_hsa041500.41013933
108FoxO signaling pathway_Homo sapiens_hsa040680.40323342
109Cysteine and methionine metabolism_Homo sapiens_hsa002700.37342129
110Amoebiasis_Homo sapiens_hsa051460.37178465
111Focal adhesion_Homo sapiens_hsa045100.36110522
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.35501564
113Fatty acid biosynthesis_Homo sapiens_hsa000610.34169321
114Metabolic pathways_Homo sapiens_hsa011000.33507518
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.33227601
116Thyroid hormone synthesis_Homo sapiens_hsa049180.31122918
117AMPK signaling pathway_Homo sapiens_hsa041520.30491574
118Adherens junction_Homo sapiens_hsa045200.29577885
119Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.29437342
120Bladder cancer_Homo sapiens_hsa052190.28622396
121Insulin signaling pathway_Homo sapiens_hsa049100.28105271
122Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.25738713
123Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.18826681
124Sulfur relay system_Homo sapiens_hsa041220.16222473

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