SLC35G1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal cholesterol absorption (GO:0030299)5.84654905
2intestinal absorption (GO:0050892)5.65616603
3CENP-A containing nucleosome assembly (GO:0034080)4.32771153
4UDP-N-acetylglucosamine metabolic process (GO:0006047)4.28001735
5intestinal epithelial cell development (GO:0060576)4.27351418
6chromatin remodeling at centromere (GO:0031055)4.20752878
7protein localization to kinetochore (GO:0034501)4.16121202
8mitotic metaphase plate congression (GO:0007080)4.15896616
9kinetochore organization (GO:0051383)4.11040266
10sulfur amino acid catabolic process (GO:0000098)4.11014490
11protein localization to chromosome, centromeric region (GO:0071459)4.08295250
12kinetochore assembly (GO:0051382)3.96894534
13cysteine metabolic process (GO:0006534)3.96456888
14homocysteine metabolic process (GO:0050667)3.95195839
15metaphase plate congression (GO:0051310)3.92584701
16serine family amino acid catabolic process (GO:0009071)3.91318084
17folic acid metabolic process (GO:0046655)3.85903823
18glycine metabolic process (GO:0006544)3.85877444
19bile acid and bile salt transport (GO:0015721)3.82802991
20DNA replication checkpoint (GO:0000076)3.80127498
21triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.80039580
22L-phenylalanine metabolic process (GO:0006558)3.72333737
23erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.72333737
24regulation of bile acid biosynthetic process (GO:0070857)3.65059707
25regulation of DNA methylation (GO:0044030)3.64278662
26urea cycle (GO:0000050)3.63103422
27urea metabolic process (GO:0019627)3.63103422
28drug catabolic process (GO:0042737)3.62340228
29regulation of meiosis I (GO:0060631)3.60583108
30erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.54734550
31L-phenylalanine catabolic process (GO:0006559)3.54734550
32histone exchange (GO:0043486)3.51521864
33purine nucleobase biosynthetic process (GO:0009113)3.47685705
34mitotic sister chromatid cohesion (GO:0007064)3.46705409
35serine family amino acid metabolic process (GO:0009069)3.46228718
36centriole replication (GO:0007099)3.43386038
37proline biosynthetic process (GO:0006561)3.40281749
38DNA strand elongation involved in DNA replication (GO:0006271)3.40105461
39negative regulation of sterol transport (GO:0032372)3.39532838
40negative regulation of cholesterol transport (GO:0032375)3.39532838
41aromatic amino acid family catabolic process (GO:0009074)3.38105387
42protein localization to chromosome (GO:0034502)3.37154695
43serine family amino acid biosynthetic process (GO:0009070)3.37003217
44cellular glucuronidation (GO:0052695)3.35038145
45DNA strand elongation (GO:0022616)3.33846910
46piRNA metabolic process (GO:0034587)3.33038174
47translesion synthesis (GO:0019985)3.32254315
48nucleotide-sugar biosynthetic process (GO:0009226)3.30831531
49establishment of chromosome localization (GO:0051303)3.28211874
50acylglycerol homeostasis (GO:0055090)3.27889317
51triglyceride homeostasis (GO:0070328)3.27889317
52nitrogen cycle metabolic process (GO:0071941)3.27641638
53telomere maintenance via semi-conservative replication (GO:0032201)3.27581142
54attachment of spindle microtubules to kinetochore (GO:0008608)3.25849100
55indolalkylamine catabolic process (GO:0046218)3.24445290
56tryptophan catabolic process (GO:0006569)3.24445290
57indole-containing compound catabolic process (GO:0042436)3.24445290
58regulation of cholesterol homeostasis (GO:2000188)3.24336331
59negative regulation of fatty acid biosynthetic process (GO:0045717)3.16943308
60flavonoid metabolic process (GO:0009812)3.15747118
61DNA replication-independent nucleosome organization (GO:0034724)3.15592193
62DNA replication-independent nucleosome assembly (GO:0006336)3.15592193
63high-density lipoprotein particle remodeling (GO:0034375)3.14734123
64DNA unwinding involved in DNA replication (GO:0006268)3.14559899
65nucleobase biosynthetic process (GO:0046112)3.14556113
66lipoprotein metabolic process (GO:0042157)3.14483055
67folic acid-containing compound biosynthetic process (GO:0009396)3.13797588
68tryptophan metabolic process (GO:0006568)3.13097153
69regulation of mitotic spindle checkpoint (GO:1903504)3.12805431
70regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.12805431
71amino-acid betaine metabolic process (GO:0006577)3.11553477
72regulation of centrosome cycle (GO:0046605)3.10693314
73kynurenine metabolic process (GO:0070189)3.09809350
74pyrimidine-containing compound transmembrane transport (GO:0072531)3.08292353
75respiratory chain complex IV assembly (GO:0008535)3.07718628
76regulation of triglyceride catabolic process (GO:0010896)3.07674050
77drug metabolic process (GO:0017144)3.07280418
78regulation of centriole replication (GO:0046599)3.06494931
79plasma lipoprotein particle assembly (GO:0034377)3.04791952
80postreplication repair (GO:0006301)3.04132204
81regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.03647071
82vitamin transport (GO:0051180)3.03180728
83cholesterol homeostasis (GO:0042632)3.03151410
84nucleotide-excision repair, DNA gap filling (GO:0006297)3.02957953
85mitotic chromosome condensation (GO:0007076)3.02768870
86sterol homeostasis (GO:0055092)3.01873425
87phospholipid efflux (GO:0033700)3.00072113
88bile acid metabolic process (GO:0008206)2.99761359
89very-low-density lipoprotein particle assembly (GO:0034379)2.98695496
90positive regulation of mitotic sister chromatid separation (GO:1901970)2.97743412
91positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.97743412
92positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.97743412
93vitamin transmembrane transport (GO:0035461)2.97249993
94meiotic cell cycle (GO:0051321)2.96005092
95telomere maintenance via recombination (GO:0000722)2.94844994
96reverse cholesterol transport (GO:0043691)2.93498766
97purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.92338672
983-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.92338672
99positive regulation of histone H3-K4 methylation (GO:0051571)2.90374098
100DNA replication initiation (GO:0006270)2.89416322
101mitotic sister chromatid segregation (GO:0000070)2.88761182
102synapsis (GO:0007129)2.87770627
103regulation of cholesterol esterification (GO:0010872)2.87472095
104mitochondrial calcium ion transport (GO:0006851)2.86970519
105mitotic recombination (GO:0006312)2.86499299
106positive regulation of lipoprotein lipase activity (GO:0051006)2.86274296
107positive regulation of triglyceride lipase activity (GO:0061365)2.86274296
108modified amino acid transport (GO:0072337)2.85497074
109folic acid transport (GO:0015884)2.85248705
110meiotic chromosome segregation (GO:0045132)2.83949694
111proline metabolic process (GO:0006560)2.82930377
112regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.82132141
113heme transport (GO:0015886)2.81759751
114pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.81267880
115spindle checkpoint (GO:0031577)2.81072846
116exogenous drug catabolic process (GO:0042738)2.80418025
117protein-lipid complex remodeling (GO:0034368)2.78520485
118macromolecular complex remodeling (GO:0034367)2.78520485
119plasma lipoprotein particle remodeling (GO:0034369)2.78520485
120glyoxylate metabolic process (GO:0046487)2.77860736
121aromatic amino acid family metabolic process (GO:0009072)2.77140417
122regulation of spindle organization (GO:0090224)2.76586817
123cholesterol efflux (GO:0033344)2.76207761
124positive regulation of chromosome segregation (GO:0051984)2.76180563
125hormone catabolic process (GO:0042447)2.74651472
126protein K6-linked ubiquitination (GO:0085020)2.73476792
127uronic acid metabolic process (GO:0006063)2.72908621
128glucuronate metabolic process (GO:0019585)2.72908621
129transcytosis (GO:0045056)2.72500895
130folic acid-containing compound metabolic process (GO:0006760)2.72454956
131ventricular cardiac muscle cell development (GO:0055015)2.71858559
132protein neddylation (GO:0045116)2.70901960
133negative regulation of transcription regulatory region DNA binding (GO:2000678)2.70597404
134regulation of spindle checkpoint (GO:0090231)2.69281481
135sister chromatid segregation (GO:0000819)2.68888777
136lysine catabolic process (GO:0006554)2.67668428
137lysine metabolic process (GO:0006553)2.67668428
138female gamete generation (GO:0007292)2.66625027
139DNA methylation involved in gamete generation (GO:0043046)2.66354335
140one-carbon metabolic process (GO:0006730)2.66171324
141replication fork processing (GO:0031297)2.65712266
142regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.65086666
143regulation of mitotic metaphase/anaphase transition (GO:0030071)2.65086666
144chromosome segregation (GO:0007059)2.65037337
145regulation of double-strand break repair via homologous recombination (GO:0010569)2.64788187
146alpha-linolenic acid metabolic process (GO:0036109)2.64765666
147regulation of histone H3-K9 methylation (GO:0051570)2.64505019
148fructose metabolic process (GO:0006000)2.63957944
149protein-lipid complex assembly (GO:0065005)2.63876160
150positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.63872639
151digestive system process (GO:0022600)2.63864913
152regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.63772818
153trophectodermal cell differentiation (GO:0001829)2.61897276
154histone-serine phosphorylation (GO:0035404)2.61697995
155nuclear pore organization (GO:0006999)2.60684205
156drug transmembrane transport (GO:0006855)2.60594669
157tetrahydrofolate metabolic process (GO:0046653)2.60483152
158regulation of protein activation cascade (GO:2000257)2.59990971
159maintenance of gastrointestinal epithelium (GO:0030277)2.59964164
160negative regulation of chromosome segregation (GO:0051985)2.59836866
161regulation of mitotic sister chromatid separation (GO:0010965)2.59804349
162regulation of mitotic sister chromatid segregation (GO:0033047)2.59804349
163regulation of sister chromatid segregation (GO:0033045)2.59804349
164formation of translation preinitiation complex (GO:0001731)2.58844973
165response to nitrosative stress (GO:0051409)2.58002073
166bile acid biosynthetic process (GO:0006699)2.57406207
167regulation of chromosome segregation (GO:0051983)2.57018479
168somatic hypermutation of immunoglobulin genes (GO:0016446)2.55636308
169somatic diversification of immune receptors via somatic mutation (GO:0002566)2.55636308
170glutamine family amino acid biosynthetic process (GO:0009084)2.55488716
171negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.54318206
172negative regulation of mitotic sister chromatid segregation (GO:0033048)2.54318206
173negative regulation of mitotic sister chromatid separation (GO:2000816)2.54318206
174negative regulation of sister chromatid segregation (GO:0033046)2.54318206
175negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.54318206
176DNA replication-dependent nucleosome assembly (GO:0006335)2.54066144
177DNA replication-dependent nucleosome organization (GO:0034723)2.54066144
178sulfur amino acid metabolic process (GO:0000096)2.53252423
179regulation of mitochondrial translation (GO:0070129)2.52944375
180drug transport (GO:0015893)2.52737677
181alpha-amino acid catabolic process (GO:1901606)2.52395538
182mitotic spindle checkpoint (GO:0071174)2.52081515
183maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.51693603
184protein autoprocessing (GO:0016540)2.51651964
185pteridine-containing compound biosynthetic process (GO:0042559)2.50427167
186binding of sperm to zona pellucida (GO:0007339)2.50128839
187pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.47429836
188telomere maintenance via telomere lengthening (GO:0010833)2.44757811
189somite rostral/caudal axis specification (GO:0032525)2.43949830
190paraxial mesoderm development (GO:0048339)2.42674750
191multicellular organism reproduction (GO:0032504)2.42086717
192chromosome organization involved in meiosis (GO:0070192)2.41961747
193chromatin assembly or disassembly (GO:0006333)2.41244409
194DNA ligation (GO:0006266)2.41179637
195proteasome assembly (GO:0043248)2.40148912
196deoxyribonucleotide biosynthetic process (GO:0009263)2.39313199
197mitotic spindle assembly checkpoint (GO:0007094)2.38251626
198spindle assembly checkpoint (GO:0071173)2.37650265
199negative regulation of DNA-dependent DNA replication (GO:2000104)2.36849416
200regulation of DNA endoreduplication (GO:0032875)2.36486007

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.01612046
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.76731134
3RXR_22158963_ChIP-Seq_LIVER_Mouse3.69882645
4PPARA_22158963_ChIP-Seq_LIVER_Mouse3.57430312
5EGR1_23403033_ChIP-Seq_LIVER_Mouse2.85157483
6LXR_22158963_ChIP-Seq_LIVER_Mouse2.75636658
7FOXM1_23109430_ChIP-Seq_U2OS_Human2.73961499
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.65994102
9MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.65143939
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.64720919
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.62104809
12AR_21909140_ChIP-Seq_LNCAP_Human2.42480294
13TP63_17297297_ChIP-ChIP_HaCaT_Human2.32791022
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.22815155
15CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.20747978
16HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.14864739
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.11917013
18EWS_26573619_Chip-Seq_HEK293_Human2.10709947
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.08024904
20EZH2_22144423_ChIP-Seq_EOC_Human2.05783618
21FUS_26573619_Chip-Seq_HEK293_Human1.99178452
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.93050913
23ELK1_19687146_ChIP-ChIP_HELA_Human1.90021195
24SOX2_27498859_Chip-Seq_STOMACH_Mouse1.85452386
25PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.85000751
26MYC_19079543_ChIP-ChIP_MESCs_Mouse1.84959391
27PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.78111654
28STAT3_1855785_ChIP-Seq_MESCs_Mouse1.76617034
29NOTCH1_21737748_ChIP-Seq_TLL_Human1.74489930
30FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.73753851
31MYC_19030024_ChIP-ChIP_MESCs_Mouse1.71590584
32KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.70985232
33KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.70985232
34KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.70985232
35POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.68462288
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67645740
37KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.67389327
38CREB1_15753290_ChIP-ChIP_HEK293T_Human1.66778758
39MYC_18358816_ChIP-ChIP_MESCs_Mouse1.66286265
40GATA6_25053715_ChIP-Seq_YYC3_Human1.66267834
41MYC_18940864_ChIP-ChIP_HL60_Human1.65378245
42BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.63684811
43ZNF263_19887448_ChIP-Seq_K562_Human1.63663825
44GATA4_25053715_ChIP-Seq_YYC3_Human1.59272121
45PADI4_21655091_ChIP-ChIP_MCF-7_Human1.58182105
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.57914696
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.56569677
48HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.55734821
49CDX2_20551321_ChIP-Seq_CACO-2_Human1.54758946
50IRF1_19129219_ChIP-ChIP_H3396_Human1.53622189
51TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.52842441
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.51556932
53NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.46912767
54SALL1_21062744_ChIP-ChIP_HESCs_Human1.46287003
55TTF2_22483619_ChIP-Seq_HELA_Human1.44836321
56NELFA_20434984_ChIP-Seq_ESCs_Mouse1.41759528
57JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.40892053
58STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.39243202
59SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.36636818
60NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.35246423
61E2F1_21310950_ChIP-Seq_MCF-7_Human1.35153232
62GABP_17652178_ChIP-ChIP_JURKAT_Human1.34665813
63HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.34114887
64EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33173396
65ETS1_20019798_ChIP-Seq_JURKAT_Human1.33072353
66TCF3_18692474_ChIP-Seq_MEFs_Mouse1.32444803
67KDM5A_27292631_Chip-Seq_BREAST_Human1.31448486
68KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.26888362
69MYCN_18555785_ChIP-Seq_MESCs_Mouse1.26142633
70E2F1_18555785_ChIP-Seq_MESCs_Mouse1.25556057
71GATA1_22025678_ChIP-Seq_K562_Human1.23674379
72HTT_18923047_ChIP-ChIP_STHdh_Human1.23323736
73E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20531635
74ELF1_17652178_ChIP-ChIP_JURKAT_Human1.19762224
75TAF15_26573619_Chip-Seq_HEK293_Human1.19487148
76ZNF274_21170338_ChIP-Seq_K562_Hela1.18824066
77SRF_21415370_ChIP-Seq_HL-1_Mouse1.18563872
78POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.18285443
79KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.17214880
80P300_19829295_ChIP-Seq_ESCs_Human1.16989157
81CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.16559357
82EST1_17652178_ChIP-ChIP_JURKAT_Human1.16475030
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.14943056
84KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14842339
85GABP_19822575_ChIP-Seq_HepG2_Human1.14325453
86VDR_22108803_ChIP-Seq_LS180_Human1.13418928
87HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.13070219
88PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12120843
89DCP1A_22483619_ChIP-Seq_HELA_Human1.10757276
90VDR_23849224_ChIP-Seq_CD4+_Human1.10583912
91FLI1_27457419_Chip-Seq_LIVER_Mouse1.10003897
92TP63_19390658_ChIP-ChIP_HaCaT_Human1.09009326
93YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.07945452
94TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07320532
95TCF3_18692474_ChIP-Seq_MESCs_Mouse1.06382597
96HOXB4_20404135_ChIP-ChIP_EML_Mouse1.06374804
97ZFX_18555785_ChIP-Seq_MESCs_Mouse1.05916379
98CLOCK_20551151_ChIP-Seq_293T_Human1.04877363
99NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.04174997
100NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.03792571
101OCT4_18692474_ChIP-Seq_MEFs_Mouse1.03657034
102FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.03223392
103ATF3_27146783_Chip-Seq_COLON_Human1.02582138
104MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02100833
105XRN2_22483619_ChIP-Seq_HELA_Human1.01898805
106NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.01692244
107MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.01383856
108GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01239813
109KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.98098682
110FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.98032433
111RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97201889
112MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96501727
113CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.96385691
114NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.96143149
115FOXP3_21729870_ChIP-Seq_TREG_Human0.95818021
116STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.95570351
117HNF4A_19822575_ChIP-Seq_HepG2_Human0.95390842
118ESR1_15608294_ChIP-ChIP_MCF-7_Human0.95069828
119SALL4_18804426_ChIP-ChIP_XEN_Mouse0.94988435
120CBP_20019798_ChIP-Seq_JUKART_Human0.94701746
121IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94701746
122TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.93713667
123ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93431682
124KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.93399925
125PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.93255319
126SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.92707765
127SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.92694043
128PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91927869
129CHD1_26751641_Chip-Seq_LNCaP_Human0.91586319
130AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90994431
131SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.90797254
132EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.89872552
133FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.89621998
134SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89507004
135EGR1_19374776_ChIP-ChIP_THP-1_Human0.89084461
136FOXA1_27270436_Chip-Seq_PROSTATE_Human0.88258089
137FOXA1_25329375_ChIP-Seq_VCAP_Human0.88258089
138SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.87342059
139ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.87260757
140E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.86828826
141SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86747974
142SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.86714405
143MYC_22102868_ChIP-Seq_BL_Human0.86188951
144GBX2_23144817_ChIP-Seq_PC3_Human0.85913865
145FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85329193
146SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.85175967
147NANOG_16153702_ChIP-ChIP_HESCs_Human0.84882093
148RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84680162
149TOP2B_26459242_ChIP-Seq_MCF-7_Human0.84628193
150NANOG_21062744_ChIP-ChIP_HESCs_Human0.84437484
151KAP1_22055183_ChIP-Seq_ESCs_Mouse0.84217946
152TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.83981212
153RARA_24833708_ChIP-Seq_LIVER_Mouse0.83440695
154IGF1R_20145208_ChIP-Seq_DFB_Human0.83339629
155UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.82710955
156CTBP2_25329375_ChIP-Seq_LNCAP_Human0.81821510
157ZFP57_27257070_Chip-Seq_ESCs_Mouse0.80858497
158CDX2_22108803_ChIP-Seq_LS180_Human0.79573685
159NFYB_21822215_ChIP-Seq_K562_Human0.78390163

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis5.37606085
2MP0002139_abnormal_hepatobiliary_system4.99386204
3MP0005085_abnormal_gallbladder_physiolo4.53719710
4MP0005365_abnormal_bile_salt4.11754981
5MP0001666_abnormal_nutrient_absorption3.58282168
6MP0008875_abnormal_xenobiotic_pharmacok3.05276068
7MP0008877_abnormal_DNA_methylation3.00921865
8MP0006292_abnormal_olfactory_placode2.98079345
9MP0003806_abnormal_nucleotide_metabolis2.95929785
10MP0004147_increased_porphyrin_level2.89439990
11MP0003252_abnormal_bile_duct2.83792184
12MP0010234_abnormal_vibrissa_follicle2.82837196
13MP0004264_abnormal_extraembryonic_tissu2.78416283
14MP0003693_abnormal_embryo_hatching2.72491893
15MP0009840_abnormal_foam_cell2.58832956
16MP0008789_abnormal_olfactory_epithelium2.23895607
17MP0010329_abnormal_lipoprotein_level2.18092159
18MP0010030_abnormal_orbit_morphology1.96858291
19MP0004019_abnormal_vitamin_homeostasis1.95212131
20MP0004957_abnormal_blastocyst_morpholog1.93593045
21MP0010352_gastrointestinal_tract_polyps1.91343263
22MP0002234_abnormal_pharynx_morphology1.90370717
23MP0003868_abnormal_feces_composition1.87777319
24MP0001293_anophthalmia1.86019077
25MP0005394_taste/olfaction_phenotype1.75433849
26MP0005499_abnormal_olfactory_system1.75433849
27MP0003111_abnormal_nucleus_morphology1.69729980
28MP0000372_irregular_coat_pigmentation1.68539291
29MP0005083_abnormal_biliary_tract1.62685283
30MP0000609_abnormal_liver_physiology1.62463885
31MP0005332_abnormal_amino_acid1.61676666
32MP0000490_abnormal_crypts_of1.60856093
33MP0003705_abnormal_hypodermis_morpholog1.57255233
34MP0009384_cardiac_valve_regurgitation1.55996696
35MP0008057_abnormal_DNA_replication1.53041311
36MP0002938_white_spotting1.43431278
37MP0001873_stomach_inflammation1.40278744
38MP0003718_maternal_effect1.40275066
39MP0000462_abnormal_digestive_system1.38479772
40MP0003950_abnormal_plasma_membrane1.36348400
41MP0010094_abnormal_chromosome_stability1.35633209
42MP0001661_extended_life_span1.30754383
43MP0002233_abnormal_nose_morphology1.29546525
44MP0001929_abnormal_gametogenesis1.23915677
45MP0002138_abnormal_hepatobiliary_system1.21715077
46MP0005319_abnormal_enzyme/_coenzyme1.21516733
47MP0001764_abnormal_homeostasis1.21064872
48MP0002210_abnormal_sex_determination1.20315523
49MP0002118_abnormal_lipid_homeostasis1.19965721
50MP0009643_abnormal_urine_homeostasis1.18757368
51MP0003077_abnormal_cell_cycle1.17820712
52MP0003300_gastrointestinal_ulcer1.17679417
53MP0003866_abnormal_defecation1.17453808
54MP0008004_abnormal_stomach_pH1.16559849
55MP0000477_abnormal_intestine_morphology1.15699656
56MP0000427_abnormal_hair_cycle1.14859948
57MP0003195_calcinosis1.14057744
58MP0003191_abnormal_cellular_cholesterol1.13623689
59MP0004215_abnormal_myocardial_fiber1.11908618
60MP0010155_abnormal_intestine_physiology1.09458053
61MP0000653_abnormal_sex_gland1.09141247
62MP0003937_abnormal_limbs/digits/tail_de1.08418651
63MP0002160_abnormal_reproductive_system1.08117428
64MP0005220_abnormal_exocrine_pancreas1.07625029
65MP0001730_embryonic_growth_arrest1.06406731
66MP0003890_abnormal_embryonic-extraembry1.05436626
67MP0002084_abnormal_developmental_patter1.04823232
68MP0009697_abnormal_copulation1.04602198
69MP0000631_abnormal_neuroendocrine_gland1.03481327
70MP0002736_abnormal_nociception_after1.02392540
71MP0006036_abnormal_mitochondrial_physio0.99434559
72MP0005174_abnormal_tail_pigmentation0.99426598
73MP0005410_abnormal_fertilization0.98385204
74MP0003315_abnormal_perineum_morphology0.97346155
75MP0001145_abnormal_male_reproductive0.97320118
76MP0010307_abnormal_tumor_latency0.96858705
77MP0004043_abnormal_pH_regulation0.96594732
78MP0008007_abnormal_cellular_replicative0.95772329
79MP0005501_abnormal_skin_physiology0.95605524
80MP0003656_abnormal_erythrocyte_physiolo0.93202786
81MP0001672_abnormal_embryogenesis/_devel0.92559061
82MP0005380_embryogenesis_phenotype0.92559061
83MP0002102_abnormal_ear_morphology0.92439943
84MP0000598_abnormal_liver_morphology0.91815409
85MP0008872_abnormal_physiological_respon0.91744602
86MP0003699_abnormal_female_reproductive0.91456514
87MP0000049_abnormal_middle_ear0.91347383
88MP0006054_spinal_hemorrhage0.89971186
89MP0002086_abnormal_extraembryonic_tissu0.89503896
90MP0001286_abnormal_eye_development0.88336154
91MP0005646_abnormal_pituitary_gland0.88159472
92MP0003186_abnormal_redox_activity0.88074632
93MP0003119_abnormal_digestive_system0.88015444
94MP0002085_abnormal_embryonic_tissue0.87525474
95MP0002876_abnormal_thyroid_physiology0.86026167
96MP0006072_abnormal_retinal_apoptosis0.85411409
97MP0002009_preneoplasia0.85197144
98MP0000678_abnormal_parathyroid_gland0.84241640
99MP0002697_abnormal_eye_size0.84057968
100MP0008058_abnormal_DNA_repair0.82960906
101MP0005381_digestive/alimentary_phenotyp0.82449050
102MP0003453_abnormal_keratinocyte_physiol0.82265229
103MP0001663_abnormal_digestive_system0.82169892
104MP0005451_abnormal_body_composition0.81875587
105MP0002161_abnormal_fertility/fecundity0.80722417
106MP0000428_abnormal_craniofacial_morphol0.80157318
107MP0002796_impaired_skin_barrier0.79025809
108MP0005636_abnormal_mineral_homeostasis0.78911818
109MP0000613_abnormal_salivary_gland0.78890791
110MP0003984_embryonic_growth_retardation0.78030448
111MP0002088_abnormal_embryonic_growth/wei0.77644486
112MP0003698_abnormal_male_reproductive0.77374267
113MP0001664_abnormal_digestion0.77210800
114MP0000350_abnormal_cell_proliferation0.75313679
115MP0002098_abnormal_vibrissa_morphology0.75213951
116MP0002092_abnormal_eye_morphology0.73268477
117MP0002111_abnormal_tail_morphology0.72508350
118MP0009053_abnormal_anal_canal0.71742191
119MP0002254_reproductive_system_inflammat0.71476366
120MP0001188_hyperpigmentation0.71279822
121MP0010678_abnormal_skin_adnexa0.70863680
122MP0005084_abnormal_gallbladder_morpholo0.70160536
123MP0000537_abnormal_urethra_morphology0.69655958
124MP0001119_abnormal_female_reproductive0.68877974
125MP0005551_abnormal_eye_electrophysiolog0.68706176
126MP0000566_synostosis0.68017634
127MP0003755_abnormal_palate_morphology0.67880296
128MP0003786_premature_aging0.67744414
129MP0003183_abnormal_peptide_metabolism0.67574296
130MP0005408_hypopigmentation0.67292090
131MP0003878_abnormal_ear_physiology0.67017426
132MP0005377_hearing/vestibular/ear_phenot0.67017426
133MP0005187_abnormal_penis_morphology0.66805899
134MP0004197_abnormal_fetal_growth/weight/0.66672853
135MP0001697_abnormal_embryo_size0.66588763
136MP0001529_abnormal_vocalization0.66202494
137MP0008932_abnormal_embryonic_tissue0.66159721
138MP0000470_abnormal_stomach_morphology0.66004617
139MP0003567_abnormal_fetal_cardiomyocyte0.63993436
140MP0005266_abnormal_metabolism0.63052082
141MP0001216_abnormal_epidermal_layer0.62692237
142MP0002095_abnormal_skin_pigmentation0.62522277
143MP0005248_abnormal_Harderian_gland0.62307407
144MP0001756_abnormal_urination0.61875958
145MP0002080_prenatal_lethality0.61263290
146MP0002877_abnormal_melanocyte_morpholog0.59659100
147MP0009642_abnormal_blood_homeostasis0.59617956
148MP0002019_abnormal_tumor_incidence0.58883875
149MP0009333_abnormal_splenocyte_physiolog0.58218864
150MP0005647_abnormal_sex_gland0.57630443
151MP0005395_other_phenotype0.57431564
152MP0005076_abnormal_cell_differentiation0.57105364
153MP0002132_abnormal_respiratory_system0.56032154
154MP0002136_abnormal_kidney_physiology0.55256980

Predicted human phenotypes

RankGene SetZ-score
1Hypobetalipoproteinemia (HP:0003563)5.24349794
2Intrahepatic cholestasis (HP:0001406)4.99806762
3Abnormality of monocarboxylic acid metabolism (HP:0010996)4.95745329
4Hyperglycinuria (HP:0003108)4.15810236
5Short middle phalanx of the 5th finger (HP:0004220)4.04671576
6Abnormality of aromatic amino acid family metabolism (HP:0004338)3.97362788
7Ileus (HP:0002595)3.83340341
8Hyperglycinemia (HP:0002154)3.78422294
9Xanthomatosis (HP:0000991)3.77883276
10Hypoglycemic coma (HP:0001325)3.60219491
11Malnutrition (HP:0004395)3.59659631
12Abnormality of glutamine family amino acid metabolism (HP:0010902)3.58457857
13Fat malabsorption (HP:0002630)3.55938014
14Hypolipoproteinemia (HP:0010981)3.51348122
15Conjugated hyperbilirubinemia (HP:0002908)3.48629670
16Abnormality of serine family amino acid metabolism (HP:0010894)3.46157773
17Abnormality of glycine metabolism (HP:0010895)3.46157773
18Abnormality of pyrimidine metabolism (HP:0004353)3.35488539
19Abnormality of sulfur amino acid metabolism (HP:0004339)3.29503267
20Hypochromic microcytic anemia (HP:0004840)3.20746514
21Supernumerary spleens (HP:0009799)3.19111400
22Facial hemangioma (HP:0000329)3.16928893
23Renal cortical cysts (HP:0000803)3.16447944
24Deep venous thrombosis (HP:0002625)3.13655962
25Hyperammonemia (HP:0001987)3.07042012
26Acanthocytosis (HP:0001927)3.03222847
27Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.99326092
28Impulsivity (HP:0100710)2.94298462
29Abnormality of aspartate family amino acid metabolism (HP:0010899)2.92807952
30Abnormality of the intrinsic pathway (HP:0010989)2.87490454
31Abnormal tarsal ossification (HP:0008369)2.87398856
32Petechiae (HP:0000967)2.81348510
33Epidermoid cyst (HP:0200040)2.80417043
34Abnormal biliary tract morphology (HP:0012440)2.79180528
35Prolonged partial thromboplastin time (HP:0003645)2.78868287
36Abnormality of nucleobase metabolism (HP:0010932)2.78578716
37Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.69578010
38Flat acetabular roof (HP:0003180)2.69393293
39Gout (HP:0001997)2.68741750
40Abdominal distention (HP:0003270)2.61602317
41Hyperinsulinemic hypoglycemia (HP:0000825)2.60297762
42Megaloblastic anemia (HP:0001889)2.58831460
43Abnormality of the labia minora (HP:0012880)2.58378561
44Abnormality of chromosome stability (HP:0003220)2.56776907
45Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.56288252
46Abnormal cartilage morphology (HP:0002763)2.54529818
47Abnormality of purine metabolism (HP:0004352)2.50123804
48Abnormality of methionine metabolism (HP:0010901)2.48438676
49Right ventricular cardiomyopathy (HP:0011663)2.44726540
50Abnormality of the common coagulation pathway (HP:0010990)2.44285588
51Hypoglycemic seizures (HP:0002173)2.43452061
52Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.40119871
53Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.38092610
54Abnormal protein N-linked glycosylation (HP:0012347)2.38092610
55Abnormal protein glycosylation (HP:0012346)2.38092610
56Abnormal glycosylation (HP:0012345)2.38092610
57Hyperglycemia (HP:0003074)2.35338491
58Hyperlipoproteinemia (HP:0010980)2.35014803
59Type I transferrin isoform profile (HP:0003642)2.34805070
60Pustule (HP:0200039)2.32511068
61Hypoalphalipoproteinemia (HP:0003233)2.32152835
62Abnormal foot bone ossification (HP:0010675)2.30921593
63Abnormality of the phalanges of the 5th finger (HP:0004213)2.30832802
64Small intestinal stenosis (HP:0012848)2.30579332
65Duodenal stenosis (HP:0100867)2.30579332
66Abnormality of serum amino acid levels (HP:0003112)2.30230205
67Cupped ribs (HP:0000887)2.29661962
68Meckel diverticulum (HP:0002245)2.28649502
69Symptomatic seizures (HP:0011145)2.25114338
70Hypophosphatemic rickets (HP:0004912)2.24977871
71Hepatic necrosis (HP:0002605)2.24900169
72Abnormality of the renal cortex (HP:0011035)2.24556097
73Complement deficiency (HP:0004431)2.24342852
74Colon cancer (HP:0003003)2.23181797
75Ketosis (HP:0001946)2.22475957
76Aplasia/Hypoplasia of the uvula (HP:0010293)2.20508143
77Septo-optic dysplasia (HP:0100842)2.18661641
78Abnormality of the ileum (HP:0001549)2.16881718
79Volvulus (HP:0002580)2.15930974
80Biliary tract neoplasm (HP:0100574)2.13586636
81Birth length less than 3rd percentile (HP:0003561)2.12481363
82Steatorrhea (HP:0002570)2.12388301
83Multiple enchondromatosis (HP:0005701)2.11777494
84Poikilocytosis (HP:0004447)2.10959946
85Hyperbilirubinemia (HP:0002904)2.10750150
86Abnormality of urine glucose concentration (HP:0011016)2.08804251
87Glycosuria (HP:0003076)2.08804251
88Abnormality of abdominal situs (HP:0011620)2.08774285
89Abdominal situs inversus (HP:0003363)2.08774285
90Abnormality of fatty-acid metabolism (HP:0004359)2.08573008
91Overlapping toe (HP:0001845)2.08035572
92Abnormality of the duodenum (HP:0002246)2.07589565
93Abnormality of vitamin metabolism (HP:0100508)2.07367933
94Abnormality of vitamin B metabolism (HP:0004340)2.05434115
95Spastic diplegia (HP:0001264)2.05430733
96Osteomalacia (HP:0002749)2.04152436
97Esophageal varix (HP:0002040)2.04036894
98Abnormality of the vitamin B12 metabolism (HP:0004341)2.02931701
99Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.01555249
100Proximal tubulopathy (HP:0000114)2.00886641
101Oligodactyly (hands) (HP:0001180)2.00679443
102Rectal prolapse (HP:0002035)1.96815654
103Hypercholesterolemia (HP:0003124)1.96685403
104Late onset (HP:0003584)1.96573869
105Aplasia/Hypoplasia of the tibia (HP:0005772)1.96157643
106Absent radius (HP:0003974)1.95719106
107Lethargy (HP:0001254)1.95663128
108Abnormal lung lobation (HP:0002101)1.95503291
109Metaphyseal cupping (HP:0003021)1.93667209
110Abnormality of alanine metabolism (HP:0010916)1.92762285
111Hyperalaninemia (HP:0003348)1.92762285
112Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.92762285
113Microretrognathia (HP:0000308)1.91892234
114Generalized aminoaciduria (HP:0002909)1.91523807
115Irritability (HP:0000737)1.91017253
116Short tibia (HP:0005736)1.90788604
117Nausea (HP:0002018)1.89036523
118Ketoacidosis (HP:0001993)1.88643120
119Abnormality of the preputium (HP:0100587)1.87946780
120Hypoplastic iliac wings (HP:0002866)1.87767602
121Acute encephalopathy (HP:0006846)1.87345840
122Abnormal pancreas size (HP:0012094)1.86976599
123Short 5th finger (HP:0009237)1.86387041
124Reduced antithrombin III activity (HP:0001976)1.85828060
125Dicarboxylic aciduria (HP:0003215)1.85530375
126Abnormality of dicarboxylic acid metabolism (HP:0010995)1.85530375
127Medial flaring of the eyebrow (HP:0010747)1.84115364
128Ureteral duplication (HP:0000073)1.83799025
129Breast hypoplasia (HP:0003187)1.83261351
130Premature ovarian failure (HP:0008209)1.83014141
131Proximal placement of thumb (HP:0009623)1.82339875
132Hepatocellular carcinoma (HP:0001402)1.82338662
133Capillary hemangiomas (HP:0005306)1.81137748
134Increased purine levels (HP:0004368)1.79133651
135Hyperuricemia (HP:0002149)1.79133651
136Absent forearm bone (HP:0003953)1.78660081
137Aplasia involving forearm bones (HP:0009822)1.78660081
138Enlarged kidneys (HP:0000105)1.78480857
139Neoplasm of the colon (HP:0100273)1.78272269
140Abnormal enzyme/coenzyme activity (HP:0012379)1.77966269
141Chromosomal breakage induced by crosslinking agents (HP:0003221)1.77582364
142Abnormal albumin level (HP:0012116)1.75784422
143Hypoalbuminemia (HP:0003073)1.75784422
144Median cleft lip (HP:0000161)1.74837487
145Metabolic acidosis (HP:0001942)1.74821378
146Protruding tongue (HP:0010808)1.74727104
147Joint hemorrhage (HP:0005261)1.74401054
148Hypoplasia of the fovea (HP:0007750)1.73649378
149Aplasia/Hypoplasia of the fovea (HP:0008060)1.73649378
150Irregular epiphyses (HP:0010582)1.73148854
151Hepatocellular necrosis (HP:0001404)1.73059395
152Chromsome breakage (HP:0040012)1.72956575
153Myocardial infarction (HP:0001658)1.72633665
154Increased CSF lactate (HP:0002490)1.72573228
155Abnormality of proline metabolism (HP:0010907)1.71915134
156Hydroxyprolinuria (HP:0003080)1.71915134
157Abnormality of complement system (HP:0005339)1.71871569
158Abnormality of the anterior horn cell (HP:0006802)1.71508301
159Degeneration of anterior horn cells (HP:0002398)1.71508301
160Unilateral renal agenesis (HP:0000122)1.71251519
161Optic nerve hypoplasia (HP:0000609)1.71081943
162Skin nodule (HP:0200036)1.70788642
163Abnormality of alkaline phosphatase activity (HP:0004379)1.70305514
164Broad alveolar ridges (HP:0000187)1.70274606
165Cheilitis (HP:0100825)1.69762370
166Neoplasm of the small intestine (HP:0100833)1.69096603
167Increased mean platelet volume (HP:0011877)1.68875077
168Oligodactyly (HP:0012165)1.68834958
169Protuberant abdomen (HP:0001538)1.68660578
170Pancreatitis (HP:0001733)1.68471670
171Septate vagina (HP:0001153)1.68362194
172Secondary amenorrhea (HP:0000869)1.68324989

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA23.66290695
2FRK3.48522170
3CDK122.47657561
4TTK2.42651230
5MST1R2.37894663
6ACVR1B2.32810167
7PBK2.28730813
8LATS12.21584994
9WEE12.20351655
10BCKDK2.15118413
11CDK82.07036640
12BMPR1B2.05849815
13STK392.04942689
14WNK42.00858047
15NEK21.95610232
16BRSK21.82288090
17MAP2K21.82189658
18MAP3K31.79857713
19MAP4K21.76690816
20TNIK1.74092160
21MST41.74028039
22LMTK21.70969166
23AURKB1.61791685
24STK38L1.59711270
25MKNK21.59575483
26AKT31.59383163
27EIF2AK11.58042632
28NME21.53871563
29STK31.51679751
30IRAK31.50710092
31TAOK31.48349554
32CDK71.45187944
33CDK41.45022718
34PRKG21.44213280
35BRAF1.43301301
36ARAF1.42189449
37PLK11.41873287
38CDK61.39864343
39ERN11.37716415
40RPS6KB21.33840416
41STK101.33457384
42FGFR41.31218826
43BUB11.31093335
44TRIM281.28147954
45MKNK11.22013659
46NUAK11.21872938
47GRK61.21247333
48CDC71.20147901
49PKN21.19036874
50SCYL21.17643516
51PNCK1.15253253
52MELK1.15063434
53MAP3K101.14547270
54VRK11.12284948
55PTK61.11543731
56NEK11.07975046
57INSRR1.07600552
58MAP3K81.05971682
59DYRK31.05371639
60CHEK21.04277897
61STK161.04204133
62ICK0.97771343
63PASK0.96764144
64MAP3K90.96693564
65NME10.95463770
66MAPK110.94915707
67FLT30.93898925
68PIM10.93315791
69TRIB30.93006436
70PLK40.92992299
71MAP3K130.92666384
72SRPK10.92663693
73CDK90.92553513
74EIF2AK30.90490621
75VRK20.90099967
76ADRBK20.88408029
77MAP3K20.83653703
78ERBB40.83199988
79IRAK10.82929938
80DYRK1B0.81347433
81ZAK0.79250989
82OXSR10.77758629
83PRKCI0.77715763
84CSK0.76071330
85MAP3K40.75439726
86MAPKAPK50.73215764
87MAP3K110.73141675
88PLK20.72107462
89CSNK1G10.71487975
90CHEK10.70657478
91ATR0.70597318
92MET0.69095941
93STK240.69002960
94TLK10.67975289
95CSNK1G30.64411248
96PAK40.64351653
97TSSK60.64106689
98MAP2K30.64098062
99TAF10.64013258
100RIPK10.63795435
101TESK10.62621009
102MUSK0.60937837
103MTOR0.60899453
104CDK190.59332652
105ATM0.59062381
106WNK30.57668132
107MAP2K60.57610190
108STK40.57515600
109YES10.56967895
110RAF10.56725663
111CAMKK20.54618278
112GSK3A0.54053485
113PIM20.53872663
114PLK30.52823971
115PRKAA10.52451325
116BCR0.52341660
117ALK0.51438517
118CDK20.50177657
119PDK20.49996946
120NEK90.49588429
121CSNK1A1L0.48670849
122CDK10.47925728
123AURKA0.47794431
124BRSK10.47544228
125CSNK1E0.47514016
126TGFBR10.47237860
127PRKCE0.45278496
128CSNK2A20.44772331
129ERBB30.43915688
130MAPK130.43369174
131MAP2K70.42871859
132FGFR30.42416676
133PTK20.42386684
134CSNK2A10.41528782
135AKT20.41437877
136PRKCG0.41277277
137GRK10.40961220
138LATS20.40548144
139PRKAA20.40445884
140DDR20.40380239
141ZAP700.40364005
142CSNK1G20.39648092
143BRD40.38999882
144ERBB20.38884969
145NLK0.38857873
146CCNB10.37670544
147BMX0.37578018
148CDK140.31415013

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049752.84832466
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.84534453
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.64416239
4Non-homologous end-joining_Homo sapiens_hsa034502.40788829
5Folate biosynthesis_Homo sapiens_hsa007902.40025498
6Vitamin digestion and absorption_Homo sapiens_hsa049772.27821219
7Sulfur metabolism_Homo sapiens_hsa009202.25198858
8Basal transcription factors_Homo sapiens_hsa030222.23526821
9Pentose and glucuronate interconversions_Homo sapiens_hsa000402.20919450
10Nitrogen metabolism_Homo sapiens_hsa009102.17796661
11Primary bile acid biosynthesis_Homo sapiens_hsa001202.16397948
12Selenocompound metabolism_Homo sapiens_hsa004502.14128533
13Tryptophan metabolism_Homo sapiens_hsa003802.04259143
14Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.00600787
15Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.00024514
16Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.96670730
17Arginine biosynthesis_Homo sapiens_hsa002201.89265424
18Drug metabolism - other enzymes_Homo sapiens_hsa009831.84206240
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.75013450
20Fatty acid degradation_Homo sapiens_hsa000711.73520119
21Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.71321684
22Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.69715867
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.68814505
24One carbon pool by folate_Homo sapiens_hsa006701.68651693
25Vitamin B6 metabolism_Homo sapiens_hsa007501.66347855
26Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.65441189
27Histidine metabolism_Homo sapiens_hsa003401.65384147
28Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.59896391
29Starch and sucrose metabolism_Homo sapiens_hsa005001.54199793
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.53415877
31RNA degradation_Homo sapiens_hsa030181.53035758
32Caffeine metabolism_Homo sapiens_hsa002321.51498294
33Chemical carcinogenesis_Homo sapiens_hsa052041.47216713
34Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.40509392
35beta-Alanine metabolism_Homo sapiens_hsa004101.39019195
36Protein export_Homo sapiens_hsa030601.38470799
37DNA replication_Homo sapiens_hsa030301.36976429
38Glutathione metabolism_Homo sapiens_hsa004801.34218955
39Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.33682394
40Fructose and mannose metabolism_Homo sapiens_hsa000511.33538831
41Retinol metabolism_Homo sapiens_hsa008301.33263402
42Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.31009233
43PPAR signaling pathway_Homo sapiens_hsa033201.28761055
44alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.27931948
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.26628405
46Sulfur relay system_Homo sapiens_hsa041221.25278576
47Linoleic acid metabolism_Homo sapiens_hsa005911.25208588
48Bile secretion_Homo sapiens_hsa049761.24905414
49Galactose metabolism_Homo sapiens_hsa000521.23917224
50Biosynthesis of amino acids_Homo sapiens_hsa012301.22538196
51Steroid hormone biosynthesis_Homo sapiens_hsa001401.21493540
52Pentose phosphate pathway_Homo sapiens_hsa000301.19603578
53Mismatch repair_Homo sapiens_hsa034301.18764146
54Complement and coagulation cascades_Homo sapiens_hsa046101.18200883
552-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.15452932
56Arginine and proline metabolism_Homo sapiens_hsa003301.14661512
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.12006967
58Peroxisome_Homo sapiens_hsa041461.11302581
59Cyanoamino acid metabolism_Homo sapiens_hsa004601.10948913
60Fatty acid metabolism_Homo sapiens_hsa012121.10257950
61Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.10122735
62Mineral absorption_Homo sapiens_hsa049781.09390190
63Butanoate metabolism_Homo sapiens_hsa006501.06264138
64Carbon metabolism_Homo sapiens_hsa012001.06056229
65Phototransduction_Homo sapiens_hsa047441.03305888
66Phenylalanine metabolism_Homo sapiens_hsa003600.99983638
67Propanoate metabolism_Homo sapiens_hsa006400.99678246
68Oocyte meiosis_Homo sapiens_hsa041140.97191829
69ABC transporters_Homo sapiens_hsa020100.96674941
70Renin-angiotensin system_Homo sapiens_hsa046140.96291873
71Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.95537640
72RNA transport_Homo sapiens_hsa030130.94426936
73Pyrimidine metabolism_Homo sapiens_hsa002400.91766033
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.91112243
75Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.89231754
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89071948
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88798892
78Pyruvate metabolism_Homo sapiens_hsa006200.85563558
79Glycerolipid metabolism_Homo sapiens_hsa005610.83393764
80Lysine degradation_Homo sapiens_hsa003100.83026199
81Base excision repair_Homo sapiens_hsa034100.77212645
82Sphingolipid metabolism_Homo sapiens_hsa006000.77176118
83Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.75650546
84RNA polymerase_Homo sapiens_hsa030200.74914348
85Steroid biosynthesis_Homo sapiens_hsa001000.73077833
86Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70066149
87Parkinsons disease_Homo sapiens_hsa050120.68450769
88Cell cycle_Homo sapiens_hsa041100.67990287
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.66197107
90Protein digestion and absorption_Homo sapiens_hsa049740.66148450
91TGF-beta signaling pathway_Homo sapiens_hsa043500.66063714
92Huntingtons disease_Homo sapiens_hsa050160.65235099
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.62728016
94Tyrosine metabolism_Homo sapiens_hsa003500.61716115
95Oxidative phosphorylation_Homo sapiens_hsa001900.59440027
96Arachidonic acid metabolism_Homo sapiens_hsa005900.58389263
97Nucleotide excision repair_Homo sapiens_hsa034200.57663161
98Metabolic pathways_Homo sapiens_hsa011000.56526105
99mRNA surveillance pathway_Homo sapiens_hsa030150.54307408
100Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.54018615
101p53 signaling pathway_Homo sapiens_hsa041150.52010008
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51824346
103Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48139144
104Fanconi anemia pathway_Homo sapiens_hsa034600.46395577
105Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.46220929
106Homologous recombination_Homo sapiens_hsa034400.45023864
107Staphylococcus aureus infection_Homo sapiens_hsa051500.44439128
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.44295286
109Fatty acid biosynthesis_Homo sapiens_hsa000610.40466753
110Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.39730262
111Spliceosome_Homo sapiens_hsa030400.38608443
112Purine metabolism_Homo sapiens_hsa002300.34547906
113Regulation of autophagy_Homo sapiens_hsa041400.33749674
114Ribosome_Homo sapiens_hsa030100.31684559
115Intestinal immune network for IgA production_Homo sapiens_hsa046720.27258720
116Proteasome_Homo sapiens_hsa030500.26762697
117Thyroid cancer_Homo sapiens_hsa052160.24798689
118Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.24136641
119Fatty acid elongation_Homo sapiens_hsa000620.20175579
120N-Glycan biosynthesis_Homo sapiens_hsa005100.15486040

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