SLC35G3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.86488872
2spermatid development (GO:0007286)9.78393042
3cilium or flagellum-dependent cell motility (GO:0001539)9.72939104
4plasma membrane fusion (GO:0045026)9.71535582
5reproduction (GO:0000003)9.01573686
6cilium movement (GO:0003341)8.93020947
7regulation of cilium movement (GO:0003352)8.75495828
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.03437474
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G7.95589396
10negative regulation of inclusion body assembly (GO:0090084)7.28281223
11single fertilization (GO:0007338)7.21999653
12sperm capacitation (GO:0048240)7.21602721
13synaptonemal complex organization (GO:0070193)7.20292087
14response to pheromone (GO:0019236)7.13055284
15synaptonemal complex assembly (GO:0007130)6.92075005
16piRNA metabolic process (GO:0034587)6.90023224
17male meiosis (GO:0007140)6.82520940
18spermatogenesis (GO:0007283)6.76207405
19male gamete generation (GO:0048232)6.73653569
20organic cation transport (GO:0015695)6.60451517
21fertilization (GO:0009566)6.22436751
22gamete generation (GO:0007276)6.18778481
23microtubule depolymerization (GO:0007019)6.16253573
24regulation of inclusion body assembly (GO:0090083)6.03983803
25ventricular system development (GO:0021591)5.70793152
26calcium ion-dependent exocytosis (GO:0017156)5.45287788
27phosphatidylethanolamine biosynthetic process (GO:0006646)5.44453342
28germ cell development (GO:0007281)5.42865208
29cellular process involved in reproduction in multicellular organism (GO:0022412)5.35579787
30chromosome condensation (GO:0030261)5.19395714
31regulation of microtubule-based movement (GO:0060632)5.16626024
32spermatid nucleus differentiation (GO:0007289)5.08806552
33microtubule severing (GO:0051013)5.04585191
34DNA packaging (GO:0006323)4.93924225
35cell recognition (GO:0008037)4.88754320
36multicellular organismal reproductive process (GO:0048609)4.87078040
37male meiosis I (GO:0007141)4.85730406
38phosphatidylethanolamine metabolic process (GO:0046337)4.82158384
39glycerol ether metabolic process (GO:0006662)4.78282938
40seminiferous tubule development (GO:0072520)4.69212765
41protein targeting to Golgi (GO:0000042)4.67641376
42chromosome organization involved in meiosis (GO:0070192)4.62733568
43establishment of protein localization to Golgi (GO:0072600)4.60269761
44left/right pattern formation (GO:0060972)4.54746066
45cellular ketone body metabolic process (GO:0046950)4.50830104
46sexual reproduction (GO:0019953)4.45980017
47ether metabolic process (GO:0018904)4.41288576
48DNA methylation involved in gamete generation (GO:0043046)4.34860183
49retrograde transport, vesicle recycling within Golgi (GO:0000301)4.32450415
50rRNA methylation (GO:0031167)4.13166561
51meiotic nuclear division (GO:0007126)4.11178440
52rRNA modification (GO:0000154)4.08331533
53single strand break repair (GO:0000012)4.06195742
54ketone body metabolic process (GO:1902224)4.00531217
55protein localization to Golgi apparatus (GO:0034067)3.94603247
56multicellular organismal development (GO:0007275)3.90232916
57chaperone-mediated protein complex assembly (GO:0051131)3.89151087
58meiosis I (GO:0007127)3.85465333
59sequestering of actin monomers (GO:0042989)3.85035020
60protein polyglutamylation (GO:0018095)3.72565295
61axoneme assembly (GO:0035082)3.61376281
62nucleoside diphosphate phosphorylation (GO:0006165)3.61056203
63genitalia morphogenesis (GO:0035112)3.60887343
64meiotic cell cycle (GO:0051321)3.50932959
65negative regulation of glycogen biosynthetic process (GO:0045719)3.49830844
66negative regulation of Rho protein signal transduction (GO:0035024)3.46971139
67GTP biosynthetic process (GO:0006183)3.45227264
68negative regulation of gene expression, epigenetic (GO:0045814)3.43589165
69protein refolding (GO:0042026)3.42371461
70positive regulation of action potential (GO:0045760)3.38180240
71protein K11-linked deubiquitination (GO:0035871)3.28553101
72purine deoxyribonucleotide catabolic process (GO:0009155)3.24538052
73pattern specification involved in kidney development (GO:0061004)3.23802920
74protein localization to cilium (GO:0061512)3.22305596
75xenobiotic catabolic process (GO:0042178)3.22255340
76regulation of spindle checkpoint (GO:0090231)3.21942980
77nucleus organization (GO:0006997)3.11797582
78microtubule polymerization or depolymerization (GO:0031109)3.10703337
79base-excision repair, AP site formation (GO:0006285)3.10502207
80phosphate ion transport (GO:0006817)3.09565376
81carnitine transport (GO:0015879)3.08623778
82amino-acid betaine transport (GO:0015838)3.08623778
83UTP biosynthetic process (GO:0006228)3.08476480
84monoubiquitinated protein deubiquitination (GO:0035520)3.07260631
85peptidyl-tyrosine autophosphorylation (GO:0038083)3.06798944
86cilium organization (GO:0044782)3.06251900
87RNA localization (GO:0006403)3.04186809
88glycolytic process (GO:0006096)3.02354887
89positive regulation of macrophage activation (GO:0043032)3.01045974
90peristalsis (GO:0030432)2.99306421
91mitotic sister chromatid cohesion (GO:0007064)2.98591913
92tachykinin receptor signaling pathway (GO:0007217)2.98340904
93ribosomal large subunit biogenesis (GO:0042273)2.97926085
94nephron tubule morphogenesis (GO:0072078)2.96292134
95nephron epithelium morphogenesis (GO:0072088)2.96292134
96negative regulation of mast cell activation (GO:0033004)2.96000018
97microtubule-based movement (GO:0007018)2.94564070
98interferon-gamma secretion (GO:0072643)2.94079222
99carnitine transmembrane transport (GO:1902603)2.93408232
100regulation of skeletal muscle contraction (GO:0014819)2.92000053
101regulation of mesoderm development (GO:2000380)2.90565295
102cilium assembly (GO:0042384)2.90514091
103positive regulation of Rab GTPase activity (GO:0032851)2.86151745
104regulation of Rab GTPase activity (GO:0032313)2.86151745
105RNA destabilization (GO:0050779)2.84462295
106cellular component assembly involved in morphogenesis (GO:0010927)2.83959423
107intraciliary transport (GO:0042073)2.82556540
108UTP metabolic process (GO:0046051)2.81381571
109regulation of G0 to G1 transition (GO:0070316)2.79977521
110indole-containing compound metabolic process (GO:0042430)2.78676488
111positive regulation of guanylate cyclase activity (GO:0031284)2.75986714
112meiotic cell cycle process (GO:1903046)2.72289258
113pharyngeal system development (GO:0060037)2.71830906
114polyol catabolic process (GO:0046174)2.71783010
115polyamine biosynthetic process (GO:0006596)2.71225394
116cilium morphogenesis (GO:0060271)2.69360729
117benzene-containing compound metabolic process (GO:0042537)2.69094940
118head development (GO:0060322)2.69036108
119musculoskeletal movement (GO:0050881)2.68566033
120multicellular organismal movement (GO:0050879)2.68566033
121detection of light stimulus involved in sensory perception (GO:0050962)2.68315995
122detection of light stimulus involved in visual perception (GO:0050908)2.68315995
123negative regulation of glycogen metabolic process (GO:0070874)2.66039455
124alditol metabolic process (GO:0019400)2.64652083
125G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.64483880
126mast cell activation (GO:0045576)2.64338533
127chromatin silencing (GO:0006342)2.64287155
128regulation of cilium assembly (GO:1902017)2.63507481
129urate metabolic process (GO:0046415)2.62406669
130protein-DNA complex disassembly (GO:0032986)2.60073844
131nucleosome disassembly (GO:0006337)2.60073844
132regulation of cardioblast proliferation (GO:0003264)2.58980605
133regulation of secondary heart field cardioblast proliferation (GO:0003266)2.58980605
134negative regulation of organelle assembly (GO:1902116)2.58423159
135alanine transport (GO:0032328)2.56504491
136regulation of regulatory T cell differentiation (GO:0045589)2.54570933
137transmission of nerve impulse (GO:0019226)2.52358647
138gene silencing by RNA (GO:0031047)2.51764860
139indole-containing compound catabolic process (GO:0042436)2.51231020
140indolalkylamine catabolic process (GO:0046218)2.51231020
141tryptophan catabolic process (GO:0006569)2.51231020
142positive regulation of endothelial cell differentiation (GO:0045603)2.50438355
143synapsis (GO:0007129)2.49911991
144centriole replication (GO:0007099)2.48516914
145regulation of guanylate cyclase activity (GO:0031282)2.48495433
146regulation of action potential (GO:0098900)2.47786801
147sperm motility (GO:0030317)13.9615133
148fusion of sperm to egg plasma membrane (GO:0007342)12.7673794
149cell wall macromolecule metabolic process (GO:0044036)12.6876826
150cell wall macromolecule catabolic process (GO:0016998)12.6876826
151acrosome reaction (GO:0007340)12.2276119
152sperm-egg recognition (GO:0035036)11.3683807
153acrosome assembly (GO:0001675)11.1173962
154epithelial cilium movement (GO:0003351)10.5531360
155axonemal dynein complex assembly (GO:0070286)10.5483133
156binding of sperm to zona pellucida (GO:0007339)10.4873159
157multicellular organism reproduction (GO:0032504)10.3174330
158cell-cell recognition (GO:0009988)10.1754743

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.70580517
2EZH2_22144423_ChIP-Seq_EOC_Human4.03815822
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.69476707
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.43100684
5GATA1_22025678_ChIP-Seq_K562_Human3.41933813
6STAT6_21828071_ChIP-Seq_BEAS2B_Human3.26436161
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.96503507
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.93426386
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.78783609
10CTBP1_25329375_ChIP-Seq_LNCAP_Human2.53498900
11GATA1_26923725_Chip-Seq_HPCs_Mouse2.35906619
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.26764769
13CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.25532132
14AR_21572438_ChIP-Seq_LNCaP_Human2.23674717
15CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.18243958
16FUS_26573619_Chip-Seq_HEK293_Human2.17735942
17ER_23166858_ChIP-Seq_MCF-7_Human2.16590301
18VDR_22108803_ChIP-Seq_LS180_Human2.13381524
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.08731837
20VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.95924675
21UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.92809310
22AUTS2_25519132_ChIP-Seq_293T-REX_Human1.89708470
23FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.80194259
24ELK4_26923725_Chip-Seq_MESODERM_Mouse1.78784104
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.78301050
26GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.73634427
27RUNX_20019798_ChIP-Seq_JUKART_Human1.72111235
28SOX2_22085726_ChIP-Seq_NPCs_Mouse1.71291871
29STAT1_17558387_ChIP-Seq_HELA_Human1.71046529
30ZNF274_21170338_ChIP-Seq_K562_Hela1.69248784
31KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.67070708
32DROSHA_22980978_ChIP-Seq_HELA_Human1.65463776
33TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.63659160
34JARID2_20064375_ChIP-Seq_MESCs_Mouse1.61199901
35MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.59027468
36WDR5_24793694_ChIP-Seq_LNCAP_Human1.57091471
37BMI1_23680149_ChIP-Seq_NPCS_Mouse1.54202079
38P300_19829295_ChIP-Seq_ESCs_Human1.53997171
39EZH2_27304074_Chip-Seq_ESCs_Mouse1.53656752
40GATA3_21867929_ChIP-Seq_CD8_Mouse1.53560454
41GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.53430793
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.48376751
43GBX2_23144817_ChIP-Seq_PC3_Human1.48188824
44HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.47926290
45FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.44597177
46ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.42405142
47ETV2_25802403_ChIP-Seq_MESCs_Mouse1.40056790
48P53_21459846_ChIP-Seq_SAOS-2_Human1.39530013
49EZH2_27294783_Chip-Seq_ESCs_Mouse1.38347167
50PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.38155489
51TAL1_26923725_Chip-Seq_HPCs_Mouse1.36371448
52SUZ12_27294783_Chip-Seq_ESCs_Mouse1.36352833
53TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36177408
54SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.35517748
55LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.35221095
56KDM2B_26808549_Chip-Seq_REH_Human1.34095462
57SMAD4_21741376_ChIP-Seq_EPCs_Human1.33598949
58PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.33163445
59RUNX2_22187159_ChIP-Seq_PCA_Human1.32762573
60RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.32082477
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32071533
62CBP_20019798_ChIP-Seq_JUKART_Human1.32071533
63AR_25329375_ChIP-Seq_VCAP_Human1.32008762
64TAF2_19829295_ChIP-Seq_ESCs_Human1.31515158
65JARID2_20075857_ChIP-Seq_MESCs_Mouse1.30655859
66TDRD3_21172665_ChIP-Seq_MCF-7_Human1.30226015
67RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.29411250
68KAP1_22055183_ChIP-Seq_ESCs_Mouse1.29101954
69TP53_18474530_ChIP-ChIP_U2OS_Human1.27632211
70RAD21_21589869_ChIP-Seq_MESCs_Mouse1.25787819
71GATA3_21867929_ChIP-Seq_TH1_Mouse1.25350635
72SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.23147871
73SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.22886497
74REST_21632747_ChIP-Seq_MESCs_Mouse1.22630704
75ERA_21632823_ChIP-Seq_H3396_Human1.21355934
76CBX2_27304074_Chip-Seq_ESCs_Mouse1.21036954
77CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19626292
78GF1_26923725_Chip-Seq_HPCs_Mouse1.18583638
79EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.18536795
80TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18084580
81RAC3_21632823_ChIP-Seq_H3396_Human1.16342150
82EED_16625203_ChIP-ChIP_MESCs_Mouse1.15657651
83CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15648570
84SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.15442206
85TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15157745
86SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.14918476
87KLF5_20875108_ChIP-Seq_MESCs_Mouse1.14841157
88FOXH1_21741376_ChIP-Seq_ESCs_Human1.14700914
89NCOR_22424771_ChIP-Seq_293T_Human1.14618858
90ZFP57_27257070_Chip-Seq_ESCs_Mouse1.14457909
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.14133064
92SMRT_27268052_Chip-Seq_Bcells_Human1.13733414
93CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.13474968
94E2F1_20622854_ChIP-Seq_HELA_Human1.12854648
95BCL6_27268052_Chip-Seq_Bcells_Human1.12824614
96NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.12497866
97MYC_19829295_ChIP-Seq_ESCs_Human1.12220422
98SPI1_26923725_Chip-Seq_HPCs_Mouse1.12063660
99NFE2_27457419_Chip-Seq_LIVER_Mouse1.11159773
100TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.10743823
101NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10467906
102IRF1_19129219_ChIP-ChIP_H3396_Human1.10368196
103CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10292714
104OCT4_20526341_ChIP-Seq_ESCs_Human1.10064024
105STAT3_23295773_ChIP-Seq_U87_Human1.09938083
106GATA3_21878914_ChIP-Seq_MCF-7_Human1.09443294
107TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09212139
108TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08974061
109SMAD3_21741376_ChIP-Seq_EPCs_Human1.08920285
110ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.08885363
111MYC_27129775_Chip-Seq_CORNEA_Mouse1.08833975
112EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.08205815
113TET1_21451524_ChIP-Seq_MESCs_Mouse1.08138800
114SMAD4_21799915_ChIP-Seq_A2780_Human1.07808778
115POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07763237
116TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07763237
117MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.07741807
118EZH2_18974828_ChIP-Seq_MESCs_Mouse1.07737920
119RNF2_18974828_ChIP-Seq_MESCs_Mouse1.07737920
120CTCF_27219007_Chip-Seq_Bcells_Human1.07646997
121EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07294733
122YY1_22570637_ChIP-Seq_MALME-3M_Human1.07143893
123ELF1_20517297_ChIP-Seq_JURKAT_Human1.06795028
124PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.06302439
125PCGF2_27294783_Chip-Seq_NPCs_Mouse1.05651539
126PIAS1_25552417_ChIP-Seq_VCAP_Human1.05358507
127TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.05320490
128CTCF_20526341_ChIP-Seq_ESCs_Human1.04727346
129RXR_22108803_ChIP-Seq_LS180_Human1.04398185
130PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04303706
131RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03461042
132RBPJ_22232070_ChIP-Seq_NCS_Mouse1.03420174
133ERG_20517297_ChIP-Seq_VCAP_Human1.03358055
134RXRA_24833708_ChIP-Seq_LIVER_Mouse1.03127034
135RUNX1_26923725_Chip-Seq_HPCs_Mouse1.02946588
136ESET_19884257_ChIP-Seq_ESCs_Mouse1.02704193
137FOXA1_25329375_ChIP-Seq_VCAP_Human1.02159796
138FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02159796
139PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.02158457
140STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.01535913
141SMAD3_21741376_ChIP-Seq_ESCs_Human1.00965876
142PRDM14_20953172_ChIP-Seq_ESCs_Human1.00928473
143GATA1_19941827_ChIP-Seq_MEL86_Mouse1.00574011
144AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00386427
145RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.00197722
146SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99669848
147GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99567050
148RARA_24833708_ChIP-Seq_LIVER_Mouse0.99069802
149MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.98649740
150NFIB_24661679_ChIP-Seq_LUNG_Mouse0.98202275
151NANOG_19829295_ChIP-Seq_ESCs_Human0.97712724
152SOX2_19829295_ChIP-Seq_ESCs_Human0.97712724
153SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97457933
154OCT1_27270436_Chip-Seq_PROSTATE_Human0.96527673
155SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.96195625
156SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95765012
157CRX_20693478_ChIP-Seq_RETINA_Mouse0.95722849
158JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.95401430
159BCOR_27268052_Chip-Seq_Bcells_Human0.93542435
160FLI1_21867929_ChIP-Seq_CD8_Mouse0.93032580
161LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.92446519
162KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.92429248
163CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91566373
164NANOG_20526341_ChIP-Seq_ESCs_Human0.90523691
165NANOG_18555785_Chip-Seq_ESCs_Mouse0.89967296
166PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89302441
167SOX2_21211035_ChIP-Seq_LN229_Human0.88603867
168SOX11_22085726_ChIP-Seq_ESNs_Mouse0.88320370
169SMC3_22415368_ChIP-Seq_MEFs_Mouse0.88202681
170NFYB_21822215_ChIP-Seq_K562_Human0.86743349
171OCT4_18555785_Chip-Seq_ESCs_Mouse0.86654794
172PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86417870
173SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.85712775

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.06377838
2MP0001929_abnormal_gametogenesis5.53707574
3MP0005257_abnormal_intraocular_pressure3.95391783
4MP0008877_abnormal_DNA_methylation3.69729166
5MP0002210_abnormal_sex_determination3.38528689
6MP0002161_abnormal_fertility/fecundity3.29096436
7MP0005670_abnormal_white_adipose2.99389851
8MP0001145_abnormal_male_reproductive2.87308492
9MP0005379_endocrine/exocrine_gland_phen2.64432187
10MP0004510_myositis2.58600109
11MP0000653_abnormal_sex_gland2.46311253
12MP0002653_abnormal_ependyma_morphology2.44387898
13MP0000678_abnormal_parathyroid_gland2.25438064
14MP0004885_abnormal_endolymph2.06327803
15MP0005410_abnormal_fertilization16.5651330
16MP0008872_abnormal_physiological_respon1.95964736
17MP0005645_abnormal_hypothalamus_physiol1.91477941
18MP0001486_abnormal_startle_reflex1.78663664
19MP0001485_abnormal_pinna_reflex1.74828766
20MP0002160_abnormal_reproductive_system1.74114665
21MP0005623_abnormal_meninges_morphology1.72343396
22MP0003718_maternal_effect1.57868898
23MP0002138_abnormal_hepatobiliary_system1.57660233
24MP0005423_abnormal_somatic_nervous1.53974069
25MP0009379_abnormal_foot_pigmentation1.51864406
26MP0002735_abnormal_chemical_nociception1.50143434
27MP0003646_muscle_fatigue1.49292792
28MP0001501_abnormal_sleep_pattern1.40561040
29MP0003283_abnormal_digestive_organ1.36658831
30MP0005671_abnormal_response_to1.32393064
31MP0004233_abnormal_muscle_weight1.29139139
32MP0002282_abnormal_trachea_morphology1.28971752
33MP0002163_abnormal_gland_morphology1.24913460
34MP0001968_abnormal_touch/_nociception1.24004604
35MP0009053_abnormal_anal_canal1.19163340
36MP0006292_abnormal_olfactory_placode1.18402242
37MP0000049_abnormal_middle_ear1.16848175
38MP0003137_abnormal_impulse_conducting1.14839136
39MP0003136_yellow_coat_color1.13599926
40MP0001919_abnormal_reproductive_system1.09998610
41MP0004142_abnormal_muscle_tone1.09571244
42MP0004742_abnormal_vestibular_system1.07930745
43MP0000026_abnormal_inner_ear1.06559430
44MP0001765_abnormal_ion_homeostasis1.04560016
45MP0001963_abnormal_hearing_physiology1.04502941
46MP0004215_abnormal_myocardial_fiber1.04295565
47MP0006072_abnormal_retinal_apoptosis1.02514930
48MP0001440_abnormal_grooming_behavior1.01347112
49MP0009745_abnormal_behavioral_response1.00295533
50MP0004085_abnormal_heartbeat1.00058556
51MP0003119_abnormal_digestive_system0.98570030
52MP0000631_abnormal_neuroendocrine_gland0.93970588
53MP0004145_abnormal_muscle_electrophysio0.88938582
54MP0001970_abnormal_pain_threshold0.88372020
55MP0002733_abnormal_thermal_nociception0.87599791
56MP0002229_neurodegeneration0.86771996
57MP0005647_abnormal_sex_gland0.86487807
58MP0000467_abnormal_esophagus_morphology0.83933714
59MP0001984_abnormal_olfaction0.83360990
60MP0003011_delayed_dark_adaptation0.83145938
61MP0000955_abnormal_spinal_cord0.83048273
62MP0008058_abnormal_DNA_repair0.81291490
63MP0003183_abnormal_peptide_metabolism0.80768197
64MP0002234_abnormal_pharynx_morphology0.80106390
65MP0005389_reproductive_system_phenotype0.79252912
66MP0008995_early_reproductive_senescence0.78479247
67MP0002837_dystrophic_cardiac_calcinosis0.76323586
68MP0005310_abnormal_salivary_gland0.75798285
69MP0004859_abnormal_synaptic_plasticity0.75642178
70MP0003635_abnormal_synaptic_transmissio0.74030322
71MP0002272_abnormal_nervous_system0.73526254
72MP0003115_abnormal_respiratory_system0.73168374
73MP0002572_abnormal_emotion/affect_behav0.73122679
74MP0009046_muscle_twitch0.72726897
75MP0006276_abnormal_autonomic_nervous0.72596408
76MP0002734_abnormal_mechanical_nocicepti0.70843389
77MP0002067_abnormal_sensory_capabilities0.70574276
78MP0003878_abnormal_ear_physiology0.69455906
79MP0005377_hearing/vestibular/ear_phenot0.69455906
80MP0000230_abnormal_systemic_arterial0.67986054
81MP0009278_abnormal_bone_marrow0.67425748
82MP0002249_abnormal_larynx_morphology0.66195995
83MP0005397_hematopoietic_system_phenotyp0.65779065
84MP0001545_abnormal_hematopoietic_system0.65779065
85MP0005409_darkened_coat_color0.65772770
86MP0005666_abnormal_adipose_tissue0.63689720
87MP0005646_abnormal_pituitary_gland0.61363321
88MP0005395_other_phenotype0.61285588
89MP0005360_urolithiasis0.60155072
90MP0009765_abnormal_xenobiotic_induced0.58330621
91MP0001905_abnormal_dopamine_level0.57837774
92MP0002063_abnormal_learning/memory/cond0.56072087
93MP0000569_abnormal_digit_pigmentation0.53920796
94MP0005636_abnormal_mineral_homeostasis0.53460492
95MP0009333_abnormal_splenocyte_physiolog0.53034383
96MP0001986_abnormal_taste_sensitivity0.51876912
97MP0009115_abnormal_fat_cell0.51862738
98MP0002557_abnormal_social/conspecific_i0.51654906
99MP0004133_heterotaxia0.51560933
100MP0002752_abnormal_somatic_nervous0.51501844
101MP0001324_abnormal_eye_pigmentation0.51362277
102MP0001800_abnormal_humoral_immune0.50156808
103MP0001293_anophthalmia0.49757932
104MP0002269_muscular_atrophy0.49160835
105MP0010094_abnormal_chromosome_stability0.49074122
106MP0000358_abnormal_cell_content/0.48001781
107MP0003329_amyloid_beta_deposits0.47837791
108MP0000534_abnormal_ureter_morphology0.46219750
109MP0002928_abnormal_bile_duct0.45802075
110MP0003699_abnormal_female_reproductive0.42796171
111MP0005253_abnormal_eye_physiology0.41801165
112MP0003950_abnormal_plasma_membrane0.39689630
113MP0005551_abnormal_eye_electrophysiolog0.38288612
114MP0001764_abnormal_homeostasis0.38275115
115MP0005391_vision/eye_phenotype0.37536585
116MP0008007_abnormal_cellular_replicative0.36695817
117MP0004036_abnormal_muscle_relaxation0.35735769
118MP0002971_abnormal_brown_adipose0.33841027
119MP0003942_abnormal_urinary_system0.32391274
120MP0006036_abnormal_mitochondrial_physio0.32133020
121MP0003633_abnormal_nervous_system0.31971308
122MP0001270_distended_abdomen0.31928632
123MP0001849_ear_inflammation0.31904726
124MP0002736_abnormal_nociception_after0.30792353
125MP0008961_abnormal_basal_metabolism0.30068072
126MP0003111_abnormal_nucleus_morphology0.29771266
127MP0002405_respiratory_system_inflammati0.29550415
128MP0003861_abnormal_nervous_system0.29386562
129MP0004808_abnormal_hematopoietic_stem0.27336423
130MP0003879_abnormal_hair_cell0.26769971
131MP0001727_abnormal_embryo_implantation0.26583332
132MP0002102_abnormal_ear_morphology0.26245429
133MP0002092_abnormal_eye_morphology0.25577575
134MP0004811_abnormal_neuron_physiology0.24510036
135MP0003786_premature_aging0.23908781
136MP0001119_abnormal_female_reproductive0.23439905
137MP0003948_abnormal_gas_homeostasis0.23178534
138MP0010307_abnormal_tumor_latency0.22945323
139MP0000313_abnormal_cell_death0.22903374
140MP0002152_abnormal_brain_morphology0.21517738
141MP0000604_amyloidosis0.21229612
142MP0001730_embryonic_growth_arrest0.21184878
143MP0002295_abnormal_pulmonary_circulatio0.20918184
144MP0003631_nervous_system_phenotype0.20769168
145MP0002169_no_abnormal_phenotype0.20448764
146MP0002873_normal_phenotype0.20243677
147MP0002084_abnormal_developmental_patter0.19884844
148MP0000751_myopathy0.19836655
149MP0002132_abnormal_respiratory_system0.19522062
150MP0001348_abnormal_lacrimal_gland0.19156700
151MP0006035_abnormal_mitochondrial_morpho0.19100390
152MP0004019_abnormal_vitamin_homeostasis0.18577307
153MP0003045_fibrosis0.17750544
154MP0005375_adipose_tissue_phenotype0.17630146
155MP0005174_abnormal_tail_pigmentation0.16502504
156MP0002909_abnormal_adrenal_gland0.15899272
157MP0003787_abnormal_imprinting0.15072721
158MP0005319_abnormal_enzyme/_coenzyme0.14126735
159MP0003936_abnormal_reproductive_system0.13762400
160MP0000249_abnormal_blood_vessel0.13635695
161MP0002970_abnormal_white_adipose0.12879043
162MP0000001_mammalian_phenotype0.12376690
163MP0003959_abnormal_lean_body0.12164275
164MP0005195_abnormal_posterior_eye0.11857964
165MP0008569_lethality_at_weaning0.11408939
166MP0008770_decreased_survivor_rate0.11123139

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.78169132
2Abnormal respiratory motile cilium morphology (HP:0005938)9.78169132
3Abnormal respiratory motile cilium physiology (HP:0012261)9.74698261
4Rhinitis (HP:0012384)8.16093261
5Abnormal ciliary motility (HP:0012262)7.93627714
6Stomach cancer (HP:0012126)7.59412159
7Chronic bronchitis (HP:0004469)7.42573581
8Severe visual impairment (HP:0001141)7.14047195
9Infertility (HP:0000789)6.70991688
10Nasal polyposis (HP:0100582)6.56764904
11Congenital stationary night blindness (HP:0007642)5.88264676
12Attenuation of retinal blood vessels (HP:0007843)5.62245355
13Abnormality of the nasal mucosa (HP:0000433)5.50655662
14Abnormal rod and cone electroretinograms (HP:0008323)4.91222357
15Bronchiectasis (HP:0002110)4.76224174
16Bronchitis (HP:0012387)4.70434022
17Male infertility (HP:0003251)4.63829796
18Pendular nystagmus (HP:0012043)4.52426675
19Generalized aminoaciduria (HP:0002909)4.33120047
20Abnormality of B cell number (HP:0010975)4.24429920
21Bony spicule pigmentary retinopathy (HP:0007737)4.12035800
22Nephronophthisis (HP:0000090)4.11927786
23Absent rod-and cone-mediated responses on ERG (HP:0007688)3.61832033
24Recurrent sinusitis (HP:0011108)3.55651562
25Autoimmune thrombocytopenia (HP:0001973)3.45595699
26Genetic anticipation (HP:0003743)3.39015376
27Abnormal spermatogenesis (HP:0008669)3.34252309
28Chronic hepatic failure (HP:0100626)3.34018011
29Recurrent otitis media (HP:0000403)3.31860404
30Abnormality of macular pigmentation (HP:0008002)3.21658769
31Abnormality of homocysteine metabolism (HP:0010919)3.13319310
32Homocystinuria (HP:0002156)3.13319310
33Autoimmune hemolytic anemia (HP:0001890)3.12699050
34Abnormality of the renal medulla (HP:0100957)3.04322682
35Pancreatic cysts (HP:0001737)2.95430493
36Recurrent bronchitis (HP:0002837)2.89007649
37Cone-rod dystrophy (HP:0000548)2.86197304
38Tubulointerstitial nephritis (HP:0001970)2.78921996
39Increased corneal curvature (HP:0100692)2.76308179
40Keratoconus (HP:0000563)2.76308179
41Methylmalonic acidemia (HP:0002912)2.74085665
42Methylmalonic aciduria (HP:0012120)2.63600708
43Tubular atrophy (HP:0000092)2.63448368
44Proximal tubulopathy (HP:0000114)2.58956162
45Progressive cerebellar ataxia (HP:0002073)2.56909263
46Impulsivity (HP:0100710)2.52618168
47Hyperkalemia (HP:0002153)2.51895223
48Molar tooth sign on MRI (HP:0002419)2.51320770
49Abnormality of midbrain morphology (HP:0002418)2.51320770
50Enlarged epiphyses (HP:0010580)2.47695020
51Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.39682490
52Optic nerve hypoplasia (HP:0000609)2.37791276
53Abnormality of chloride homeostasis (HP:0011422)2.36834149
54Tubulointerstitial abnormality (HP:0001969)2.36297881
55Abnormal gallbladder physiology (HP:0012438)2.31787262
56Cholecystitis (HP:0001082)2.31787262
57Facial shape deformation (HP:0011334)2.30120000
58Potter facies (HP:0002009)2.30120000
59Renal cortical cysts (HP:0000803)2.29415359
60Abnormality of the vitamin B12 metabolism (HP:0004341)2.25757264
61Abnormal delayed hypersensitivity skin test (HP:0002963)2.23747499
62Eosinophilia (HP:0001880)2.23178974
63Macular degeneration (HP:0000608)2.22983163
64Medial flaring of the eyebrow (HP:0010747)2.20818431
65Increased IgM level (HP:0003496)2.19951102
66Abnormality of the costochondral junction (HP:0000919)2.18661238
67Abolished electroretinogram (ERG) (HP:0000550)2.18201094
68Sclerocornea (HP:0000647)2.17341719
69Hypochromic anemia (HP:0001931)2.14784264
70Abnormality of eosinophils (HP:0001879)2.14117274
71Azoospermia (HP:0000027)2.13358160
72Gonadotropin excess (HP:0000837)2.12433231
73Colon cancer (HP:0003003)2.11498893
74Metabolic alkalosis (HP:0200114)2.09971412
75Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.08663875
76Abnormality of vitamin B metabolism (HP:0004340)2.07795832
77Hypoplastic ischia (HP:0003175)2.06692244
78Dyschromatopsia (HP:0007641)2.06366789
79Myokymia (HP:0002411)2.03559176
80Urethral obstruction (HP:0000796)2.03068793
81Absent/shortened dynein arms (HP:0200106)13.2236722
82Dynein arm defect of respiratory motile cilia (HP:0012255)13.2236722
83Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0390239
84Congenital sensorineural hearing impairment (HP:0008527)1.99021462
85Popliteal pterygium (HP:0009756)1.95721694
86Abnormality of urine glucose concentration (HP:0011016)1.93769002
87Glycosuria (HP:0003076)1.93769002
88IgG deficiency (HP:0004315)1.92899072
89Abnormality of vitamin metabolism (HP:0100508)1.92351130
90Abnormality of T cell number (HP:0011839)1.92264709
91Abnormality of T cell physiology (HP:0011840)1.92246041
92Chorioretinal atrophy (HP:0000533)1.90855561
93Tubulointerstitial fibrosis (HP:0005576)1.89543293
94Spastic tetraparesis (HP:0001285)1.89371479
95Chronic sinusitis (HP:0011109)1.87990694
96Hypokalemic alkalosis (HP:0001949)1.85828252
97Resting tremor (HP:0002322)1.85469735
98Median cleft lip (HP:0000161)1.84382519
99Symphalangism affecting the phalanges of the hand (HP:0009773)1.84191274
100Stage 5 chronic kidney disease (HP:0003774)1.83879376
101Decreased central vision (HP:0007663)1.83677377
102Postaxial foot polydactyly (HP:0001830)1.82837272
103Polyuria (HP:0000103)1.79666850
104Choroideremia (HP:0001139)1.76121534
105Unilateral renal agenesis (HP:0000122)1.75848645
106Synostosis of carpal bones (HP:0005048)1.75282420
107Abnormal number of erythroid precursors (HP:0012131)1.74129451
108Photophobia (HP:0000613)1.73269589
109Hyperthyroidism (HP:0000836)1.72738340
110Impaired proprioception (HP:0010831)1.71079042
111Abnormality of the ischium (HP:0003174)1.70758690
112Abnormality of potassium homeostasis (HP:0011042)1.70556003
113Congenital hepatic fibrosis (HP:0002612)1.69697257
114Bile duct proliferation (HP:0001408)1.68948424
115Abnormal biliary tract physiology (HP:0012439)1.68948424
116Abnormality of cells of the erythroid lineage (HP:0012130)1.67913443
117Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.67044346
118Furrowed tongue (HP:0000221)1.66996860
119Hemorrhage of the eye (HP:0011885)1.65861852
120Abnormal drinking behavior (HP:0030082)1.62814130
121Polydipsia (HP:0001959)1.62814130
122Heterotopia (HP:0002282)1.58485561
123Abnormality of dentin (HP:0010299)1.57708453
124Bell-shaped thorax (HP:0001591)1.55177270
125Oculomotor apraxia (HP:0000657)1.52783485
126Hypoplasia of the capital femoral epiphysis (HP:0003090)1.50196889
127Abnormality of renal excretion (HP:0011036)1.49867802
128Abnormality of permanent molar morphology (HP:0011071)1.49304399
129Abnormality of the dental root (HP:0006486)1.49304399
130Taurodontia (HP:0000679)1.49304399
131Neurofibrillary tangles (HP:0002185)1.49244564
132Short ribs (HP:0000773)1.47866999
133Abnormality of the lower motor neuron (HP:0002366)1.45734804
134Cystic liver disease (HP:0006706)1.42506436
135Asymmetric septal hypertrophy (HP:0001670)1.41168167
136Abnormality of molar morphology (HP:0011070)1.38744974
137Abnormality of molar (HP:0011077)1.38744974
138Abnormality of the renal cortex (HP:0011035)1.37712368
139Aplasia/Hypoplasia of the lens (HP:0008063)1.37621380
140Postaxial hand polydactyly (HP:0001162)1.37616771
141Congenital malformation of the right heart (HP:0011723)1.36517911
142Double outlet right ventricle (HP:0001719)1.36517911
143Abnormality of the dental pulp (HP:0006479)1.36278988
144Pancreatic fibrosis (HP:0100732)1.35386055
145Decreased electroretinogram (ERG) amplitude (HP:0000654)1.33112052
146Fibular hypoplasia (HP:0003038)1.30718749
147True hermaphroditism (HP:0010459)1.30699253
148Renal dysplasia (HP:0000110)1.26998317
149Deformed sella turcica (HP:0002681)1.26007945
150Constricted visual fields (HP:0001133)1.24654681
151Broad distal phalanx of finger (HP:0009836)1.22249205
152Hemiparesis (HP:0001269)1.22010659
153Bundle branch block (HP:0011710)1.21445533
154Absent frontal sinuses (HP:0002688)1.21179285
155Abnormal urine output (HP:0012590)1.20209844
156Amyotrophic lateral sclerosis (HP:0007354)1.19798167
157Easy fatigability (HP:0003388)1.19270239
158Facial cleft (HP:0002006)1.18437725
159Cerebral inclusion bodies (HP:0100314)1.18336148
160Cerebellar dysplasia (HP:0007033)1.18023090
161Loss of speech (HP:0002371)1.17997274
162Short thorax (HP:0010306)1.16959819
163Aplasia/Hypoplasia of the tongue (HP:0010295)1.16756266
164Absent epiphyses (HP:0010577)1.15457924
165Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.15457924
166Gait imbalance (HP:0002141)1.15439556
167Congenital primary aphakia (HP:0007707)1.15053728
168Nephropathy (HP:0000112)1.14477849
169Supernumerary spleens (HP:0009799)1.12390742
170Microglossia (HP:0000171)1.12261044
171Sensory axonal neuropathy (HP:0003390)1.10326280
172Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.09942546
173Fatigable weakness (HP:0003473)1.07693454
174Abnormality of the neuromuscular junction (HP:0003398)1.07693454
175Truncal obesity (HP:0001956)1.07502187

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.91770323
2PDK47.91770323
3TESK16.67055970
4PRKD35.31031903
5PDK25.08348567
6ICK4.73363074
7MAP4K23.93269468
8TXK3.54138935
9PLK43.40906196
10CAMKK22.92368269
11FRK2.68698738
12INSRR2.63059974
13DDR22.41561140
14PTK2B2.29279842
15PIK3CG2.04545302
16PLK22.01419895
17PNCK1.99326000
18STK381.91052493
19WNK41.89709421
20STK391.82813070
21IRAK41.78374764
22DYRK1B1.73112469
23NEK21.67172441
24GRK61.66938336
25MAP3K111.63015262
26NME11.62534622
27CDK191.46694571
28GRK71.46652958
29GRK11.39996418
30NTRK31.38756385
31BMPR1B1.22812161
32PDK11.17940634
33ACVR1B1.11336050
34CAMK11.04229616
35DYRK31.02337932
36MAPK150.93127288
37TYRO30.89432665
38OBSCN0.88917342
39CAMK40.85107758
40EEF2K0.80921993
41TAOK10.80045107
42WNK10.79365439
43IRAK10.75399704
44TAOK20.75099467
45MAP3K40.72079029
46RIPK40.71178481
47GRK50.69523035
48PDPK10.69221959
49KIT0.69062988
50STK30.68346206
51WNK30.67843562
52ITK0.67298987
53PASK0.66424256
54MATK0.65574620
55CAMK1G0.65545767
56CCNB10.62117762
57SIK20.60219022
58DAPK20.58774191
59CHEK20.55524036
60IRAK20.54737673
61ADRBK10.54605223
62MOS0.54206679
63TESK20.53271870
64TEC0.52764495
65PINK10.52250781
66LMTK20.51909465
67TTK0.51731748
68SYK0.50819906
69KDR0.49507857
70MAPK130.47772762
71CAMK2A0.45700184
72MAP2K60.44893256
73IGF1R0.44387191
74RPS6KA60.43036329
75ROCK10.42616390
76FLT30.42311437
77PRKACA0.42281744
78MARK20.41919691
79PAK40.41870890
80MUSK0.40462536
81PAK10.39786155
82IKBKB0.39500323
83CAMKK10.38870417
84PIK3CA0.38742969
85NTRK20.38152205
86HCK0.37227866
87LYN0.36578469
88CHEK10.36366379
89JAK30.36263977
90BLK0.36199907
91PAK20.34649515
92MAP2K30.33915992
93TRPM70.33773688
94CDK80.33223227
95PRKCG0.31076861
96BTK0.30712795
97PRKACB0.30139786
98MAP3K100.30121116
99RIPK10.30070230
100MTOR0.29438124
101CAMK2B0.29408841
102ADRBK20.29336745
103NUAK10.29049131
104CDK120.28948070
105MAP3K30.28428291
106FER0.28187753
107CSF1R0.28167545
108PRKAA20.27475523
109ATM0.27038444
110LCK0.27011518
111ERBB20.26495585
112SGK10.25587389
113TLK10.24948733
114PRKCE0.24105846
115RPS6KA20.23949899
116STK100.23675850
117MAP2K70.23668589
118JAK20.23656053
119ATR0.21892040
120MAPKAPK50.21598496
121MARK30.21158284
122PRKAA10.19125864
123PRKCQ0.17462866
124PRKG20.17358945
125PRKCZ0.14803861
126NEK60.14613397
127STK38L0.14593489
128TRIB30.13740279
129WEE10.13024721
130TGFBR20.12481653
131PLK10.10829196
132PIM10.08825069
133RPS6KB10.08819836
134CDK150.08199266
135RPS6KA10.07939337
136GSK3B0.06324792
137CDK11A0.05848746
138CDK180.04787974
139PRKG10.04693536
140CDK60.04572261
141CSNK2A10.04443175
142BUB10.04194200
143PRKCD0.04099246
144CDK40.03408798
145CDK140.02502833
146BRSK20.02401565
147ZAP700.02281587
148PRKACG0.02248052
149YES10.01800239
150MAPK80.01560817
151CSNK1D0.01400404
152PTK60.01214263
153AURKA0.00791826
154CDK20.00729341
155MAP4K10.00681579
156CLK10.00617125
157CDK10.00212482
158PKN10.00189608
159SRC-0.0264502
160PRKCB-0.0150696
161PRKCA-0.0112233
162EPHB1-0.0091087
163PDGFRB-0.0041502
164BRAF-0.0031417
165CSK-0.0022779
166STK11-0.0015532
167CSNK2A2-0.0013719
168EGFR-0.0009282

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.66022851
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.33466180
3Vitamin B6 metabolism_Homo sapiens_hsa007503.68018736
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.38781855
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.22089057
6Pyruvate metabolism_Homo sapiens_hsa006203.19663033
7Linoleic acid metabolism_Homo sapiens_hsa005913.13515937
8Phototransduction_Homo sapiens_hsa047443.11353558
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.69491322
10Olfactory transduction_Homo sapiens_hsa047402.63483052
11Glucagon signaling pathway_Homo sapiens_hsa049222.55980761
12Carbohydrate digestion and absorption_Homo sapiens_hsa049732.54742554
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.37964283
14Basal transcription factors_Homo sapiens_hsa030222.27516500
15Caffeine metabolism_Homo sapiens_hsa002322.26928446
16Propanoate metabolism_Homo sapiens_hsa006402.21273809
17Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.14498934
18Steroid hormone biosynthesis_Homo sapiens_hsa001402.12896447
19Glycerolipid metabolism_Homo sapiens_hsa005612.08112918
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.07893657
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.96271773
22Selenocompound metabolism_Homo sapiens_hsa004501.95016850
23Retinol metabolism_Homo sapiens_hsa008301.91624145
24PPAR signaling pathway_Homo sapiens_hsa033201.86928911
25Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.85253864
26Nitrogen metabolism_Homo sapiens_hsa009101.85045323
27Glycerophospholipid metabolism_Homo sapiens_hsa005641.84183357
28Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.77090917
29Dorso-ventral axis formation_Homo sapiens_hsa043201.74746042
30Nicotine addiction_Homo sapiens_hsa050331.71160269
31Ribosome_Homo sapiens_hsa030101.71069812
32Oocyte meiosis_Homo sapiens_hsa041141.68567493
33Fructose and mannose metabolism_Homo sapiens_hsa000511.62162456
34Graft-versus-host disease_Homo sapiens_hsa053321.62109506
35Glycosaminoglycan degradation_Homo sapiens_hsa005311.54724949
36Ether lipid metabolism_Homo sapiens_hsa005651.53090801
37Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.50491110
38Mineral absorption_Homo sapiens_hsa049781.50245109
39Amphetamine addiction_Homo sapiens_hsa050311.47709150
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.47256885
41Antigen processing and presentation_Homo sapiens_hsa046121.46854824
42Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.44672174
43Fat digestion and absorption_Homo sapiens_hsa049751.43288224
44Butanoate metabolism_Homo sapiens_hsa006501.41003525
45Autoimmune thyroid disease_Homo sapiens_hsa053201.40749598
46Pentose phosphate pathway_Homo sapiens_hsa000301.36699240
47Allograft rejection_Homo sapiens_hsa053301.35915631
48Fanconi anemia pathway_Homo sapiens_hsa034601.34555807
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.26545966
50Cardiac muscle contraction_Homo sapiens_hsa042601.21598404
51Morphine addiction_Homo sapiens_hsa050321.19313554
52Type I diabetes mellitus_Homo sapiens_hsa049401.17240640
53Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.16742979
54Type II diabetes mellitus_Homo sapiens_hsa049301.16385699
55Fatty acid degradation_Homo sapiens_hsa000711.16317614
56Fatty acid metabolism_Homo sapiens_hsa012121.13526377
57Carbon metabolism_Homo sapiens_hsa012001.13018246
58Renin secretion_Homo sapiens_hsa049241.10298776
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08970208
60Primary bile acid biosynthesis_Homo sapiens_hsa001201.07539162
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.07337864
62Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.05636274
63Glutathione metabolism_Homo sapiens_hsa004801.04041276
64Huntingtons disease_Homo sapiens_hsa050161.01009998
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.99368953
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99088098
67Hedgehog signaling pathway_Homo sapiens_hsa043400.95964573
68Purine metabolism_Homo sapiens_hsa002300.95175118
69Oxidative phosphorylation_Homo sapiens_hsa001900.94466564
70Drug metabolism - other enzymes_Homo sapiens_hsa009830.94262826
71Cysteine and methionine metabolism_Homo sapiens_hsa002700.94229644
72mRNA surveillance pathway_Homo sapiens_hsa030150.93976123
73Adipocytokine signaling pathway_Homo sapiens_hsa049200.91790113
74Maturity onset diabetes of the young_Homo sapiens_hsa049500.89126981
75RNA polymerase_Homo sapiens_hsa030200.87380365
76Arachidonic acid metabolism_Homo sapiens_hsa005900.87065408
77Glutamatergic synapse_Homo sapiens_hsa047240.86886423
78Central carbon metabolism in cancer_Homo sapiens_hsa052300.83622323
79Estrogen signaling pathway_Homo sapiens_hsa049150.82500575
80Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.82293526
81Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.80843447
82Legionellosis_Homo sapiens_hsa051340.78759380
83Systemic lupus erythematosus_Homo sapiens_hsa053220.76190877
84Bile secretion_Homo sapiens_hsa049760.75699843
85Collecting duct acid secretion_Homo sapiens_hsa049660.74474835
86Tryptophan metabolism_Homo sapiens_hsa003800.74354630
87Cholinergic synapse_Homo sapiens_hsa047250.74122568
88Insulin secretion_Homo sapiens_hsa049110.73530776
89Thyroid hormone synthesis_Homo sapiens_hsa049180.72749413
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72278804
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71553555
92African trypanosomiasis_Homo sapiens_hsa051430.69452429
93Starch and sucrose metabolism_Homo sapiens_hsa005000.69027874
94Primary immunodeficiency_Homo sapiens_hsa053400.68841517
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.67700160
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.64717792
97Long-term potentiation_Homo sapiens_hsa047200.64626064
98RNA transport_Homo sapiens_hsa030130.63473984
99Endocytosis_Homo sapiens_hsa041440.63410100
100Chemical carcinogenesis_Homo sapiens_hsa052040.62768551
101GABAergic synapse_Homo sapiens_hsa047270.62680175
102Alzheimers disease_Homo sapiens_hsa050100.61327661
103Jak-STAT signaling pathway_Homo sapiens_hsa046300.61032113
104ABC transporters_Homo sapiens_hsa020100.60048019
105Homologous recombination_Homo sapiens_hsa034400.59802634
106Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.57712608
107Biosynthesis of amino acids_Homo sapiens_hsa012300.57563348
108Inositol phosphate metabolism_Homo sapiens_hsa005620.57264380
109Renin-angiotensin system_Homo sapiens_hsa046140.57197172
110Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.55595094
111Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.55254807
112Parkinsons disease_Homo sapiens_hsa050120.53628733
113Oxytocin signaling pathway_Homo sapiens_hsa049210.52991436
114Phosphatidylinositol signaling system_Homo sapiens_hsa040700.51814044
115Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51527160
116Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.51266412
117Protein digestion and absorption_Homo sapiens_hsa049740.49556705
118AMPK signaling pathway_Homo sapiens_hsa041520.49459957
119Calcium signaling pathway_Homo sapiens_hsa040200.49254143
120Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48848569
121VEGF signaling pathway_Homo sapiens_hsa043700.48338502
122Hematopoietic cell lineage_Homo sapiens_hsa046400.48106786
123RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46696295
124Vascular smooth muscle contraction_Homo sapiens_hsa042700.46607599
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45840551
126Pancreatic secretion_Homo sapiens_hsa049720.44911951
127Salivary secretion_Homo sapiens_hsa049700.44636039
128Viral myocarditis_Homo sapiens_hsa054160.44007999
129T cell receptor signaling pathway_Homo sapiens_hsa046600.42967362
130B cell receptor signaling pathway_Homo sapiens_hsa046620.42920642
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39865885
132NOD-like receptor signaling pathway_Homo sapiens_hsa046210.39437303
133Gastric acid secretion_Homo sapiens_hsa049710.39287457
134Alcoholism_Homo sapiens_hsa050340.38887991
135Serotonergic synapse_Homo sapiens_hsa047260.37771207
136cAMP signaling pathway_Homo sapiens_hsa040240.36316018
137Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.35402592
138Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.33953631
139Histidine metabolism_Homo sapiens_hsa003400.30658173
140Aldosterone synthesis and secretion_Homo sapiens_hsa049250.29931234
141Synaptic vesicle cycle_Homo sapiens_hsa047210.29392148
142Metabolic pathways_Homo sapiens_hsa011000.28155470
143MAPK signaling pathway_Homo sapiens_hsa040100.27324835
144Pyrimidine metabolism_Homo sapiens_hsa002400.25322003
145HIF-1 signaling pathway_Homo sapiens_hsa040660.23783345
146Pentose and glucuronate interconversions_Homo sapiens_hsa000400.22273589
147Measles_Homo sapiens_hsa051620.21614523
148Toxoplasmosis_Homo sapiens_hsa051450.21576466
149Basal cell carcinoma_Homo sapiens_hsa052170.20234455
150Circadian entrainment_Homo sapiens_hsa047130.19932802
151Taste transduction_Homo sapiens_hsa047420.19048580
152Wnt signaling pathway_Homo sapiens_hsa043100.16822719
153Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.16638667
154Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.14328285
155Salmonella infection_Homo sapiens_hsa051320.13982062
156Cocaine addiction_Homo sapiens_hsa050300.13584559
157Viral carcinogenesis_Homo sapiens_hsa052030.13582185
158Insulin resistance_Homo sapiens_hsa049310.13574235
159Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.07555495

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