SLC38A10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)8.84347736
2proline metabolic process (GO:0006560)6.70768364
3embryonic process involved in female pregnancy (GO:0060136)5.99538340
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)5.79491036
5protein retention in ER lumen (GO:0006621)5.60063142
6establishment of apical/basal cell polarity (GO:0035089)5.29926246
7COPI coating of Golgi vesicle (GO:0048205)5.10579000
8Golgi transport vesicle coating (GO:0048200)5.10579000
9transcription from mitochondrial promoter (GO:0006390)4.86691893
10regulation of integrin activation (GO:0033623)4.72770538
11oxidative demethylation (GO:0070989)4.48890344
12establishment or maintenance of monopolar cell polarity (GO:0061339)4.43121760
13establishment of monopolar cell polarity (GO:0061162)4.43121760
14regulation of translational fidelity (GO:0006450)4.37762649
15positive regulation of protein homooligomerization (GO:0032464)4.35634213
16regulation of protein homooligomerization (GO:0032462)4.21664848
17sulfur amino acid catabolic process (GO:0000098)4.21290222
18COPII vesicle coating (GO:0048208)4.19861247
19activation of signaling protein activity involved in unfolded protein response (GO:0006987)4.18873366
20mannose metabolic process (GO:0006013)4.17241565
21negative regulation of erythrocyte differentiation (GO:0045647)4.15153155
22embryonic placenta development (GO:0001892)4.11858399
23glutamine family amino acid biosynthetic process (GO:0009084)4.03523455
24positive regulation of nuclease activity (GO:0032075)4.00891717
25negative regulation of fatty acid biosynthetic process (GO:0045717)3.87349734
264-hydroxyproline metabolic process (GO:0019471)3.86170604
27intestinal cholesterol absorption (GO:0030299)3.85752132
28protein localization to endosome (GO:0036010)3.79922805
29cellular response to ATP (GO:0071318)3.79196532
30regulation of cholesterol homeostasis (GO:2000188)3.78800120
31mitochondrial DNA metabolic process (GO:0032042)3.74265741
32mitotic G1 DNA damage checkpoint (GO:0031571)3.73141036
33glandular epithelial cell development (GO:0002068)3.62744236
34regulation of nuclease activity (GO:0032069)3.60356420
35replication fork processing (GO:0031297)3.54506134
36endoplasmic reticulum unfolded protein response (GO:0030968)3.45411464
37ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.41392922
38regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.39294956
39antigen processing and presentation of endogenous antigen (GO:0019883)3.39098853
40antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.36241584
41mitotic G1/S transition checkpoint (GO:0044819)3.31417775
42cellular response to unfolded protein (GO:0034620)3.29900790
43convergent extension (GO:0060026)3.25049398
44N-glycan processing (GO:0006491)3.24311556
45maternal placenta development (GO:0001893)3.23812567
46apoptotic cell clearance (GO:0043277)3.22974954
47antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.21226746
48negative regulation of Ras GTPase activity (GO:0034261)3.21121718
49ER-nucleus signaling pathway (GO:0006984)3.16726726
50protein heterotrimerization (GO:0070208)3.14832372
51apoptotic process involved in morphogenesis (GO:0060561)3.13152813
52negative regulation of JAK-STAT cascade (GO:0046426)3.12500925
53G1 DNA damage checkpoint (GO:0044783)3.11954483
54negative regulation of protein oligomerization (GO:0032460)3.09427364
55cellular response to topologically incorrect protein (GO:0035967)3.08315148
56regulation of extracellular matrix disassembly (GO:0010715)3.07679588
57barbed-end actin filament capping (GO:0051016)3.07240825
58pinocytosis (GO:0006907)3.07182059
59columnar/cuboidal epithelial cell development (GO:0002066)3.06837354
60anatomical structure regression (GO:0060033)3.00683537
61peptidyl-proline hydroxylation (GO:0019511)2.99249597
62basement membrane organization (GO:0071711)2.98300348
63detection of bacterium (GO:0016045)2.98069990
64L-alpha-amino acid transmembrane transport (GO:1902475)2.97923113
65trophectodermal cell differentiation (GO:0001829)2.97832822
66cellular zinc ion homeostasis (GO:0006882)2.95307318
67detection of other organism (GO:0098543)2.95210766
68response to peptidoglycan (GO:0032494)2.94815050
69spliceosomal tri-snRNP complex assembly (GO:0000244)2.93756429
70positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.92597666
71retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.91977985
72regulation of hippo signaling (GO:0035330)2.91193265
73negative regulation of cell cycle arrest (GO:0071157)2.89490986
74response to endoplasmic reticulum stress (GO:0034976)2.88751563
75dosage compensation (GO:0007549)2.88086110
76mRNA cleavage (GO:0006379)2.87614888
77response to muramyl dipeptide (GO:0032495)2.82184845
78response to laminar fluid shear stress (GO:0034616)2.80296783
79protein targeting to vacuole (GO:0006623)2.79498111
80protein targeting to lysosome (GO:0006622)2.79498111
81establishment of protein localization to vacuole (GO:0072666)2.79498111
82positive regulation of protein oligomerization (GO:0032461)2.78206285
83positive regulation by symbiont of host defense response (GO:0052509)2.77641507
84modulation by symbiont of host defense response (GO:0052031)2.77641507
85modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.77641507
86modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.77641507
87positive regulation by organism of defense response of other organism involved in symbiotic interact2.77641507
88modulation by symbiont of host immune response (GO:0052553)2.77641507
89negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.76172772
90negative regulation of fatty acid transport (GO:2000192)2.71333974
91positive regulation of Cdc42 GTPase activity (GO:0043089)2.71021968
92poly(A)+ mRNA export from nucleus (GO:0016973)2.70828876
93detection of external biotic stimulus (GO:0098581)2.70260709
94negative regulation of granulocyte differentiation (GO:0030853)2.70049330
95cellular response to zinc ion (GO:0071294)2.69529522
96regulation of early endosome to late endosome transport (GO:2000641)2.69311266
97hypotonic response (GO:0006971)2.69278703
98activation of Rac GTPase activity (GO:0032863)2.68986405
99polarized epithelial cell differentiation (GO:0030859)2.68634291
100regulation of protein oligomerization (GO:0032459)2.67500539
101antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.66866522
102negative regulation of fatty acid metabolic process (GO:0045922)2.66573253
103protein carboxylation (GO:0018214)2.65688866
104peptidyl-glutamic acid carboxylation (GO:0017187)2.65688866
105negative regulation of cell killing (GO:0031342)2.64694608
106negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.64694608
107vesicle coating (GO:0006901)2.64379439
108regulation of podosome assembly (GO:0071801)2.63944003
109stress fiber assembly (GO:0043149)2.63641625
110positive regulation of gamma-delta T cell activation (GO:0046645)2.62539210
111negative regulation of cartilage development (GO:0061037)2.61709496
112macroautophagy (GO:0016236)2.59978165
113protein hydroxylation (GO:0018126)2.59502620
114negative regulation of cell size (GO:0045792)2.58986190
115maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.58004211
116regulation of cell size (GO:0008361)2.57791819
117regulation of leukocyte degranulation (GO:0043300)2.57320561
118regulation of response to reactive oxygen species (GO:1901031)2.56870750
119alkaloid metabolic process (GO:0009820)2.56802478
120cellular response to lithium ion (GO:0071285)2.56313425
121DNA strand renaturation (GO:0000733)2.55246790
122low-density lipoprotein particle clearance (GO:0034383)2.53356261
123embryonic eye morphogenesis (GO:0048048)2.53000286
124GDP-mannose metabolic process (GO:0019673)2.52495311
125positive regulation of receptor recycling (GO:0001921)2.52005064
126positive regulation of histone deacetylation (GO:0031065)2.51451029
127urea cycle (GO:0000050)2.50420925
128positive regulation of extracellular matrix organization (GO:1903055)2.49755075
129valine metabolic process (GO:0006573)2.49567515
130positive thymic T cell selection (GO:0045059)2.48891946
131negative regulation of nucleotide catabolic process (GO:0030812)2.48839129
132epithelial cell fate commitment (GO:0072148)2.47328469
133negative regulation of GTP catabolic process (GO:0033125)2.47090383
134negative regulation of GTPase activity (GO:0034260)2.47090383
135regulation of RNA export from nucleus (GO:0046831)2.46968484
136somatic hypermutation of immunoglobulin genes (GO:0016446)2.46404284
137somatic diversification of immune receptors via somatic mutation (GO:0002566)2.46404284
138UV protection (GO:0009650)2.45878425
139regulation of myeloid leukocyte mediated immunity (GO:0002886)2.45615862
140detection of molecule of bacterial origin (GO:0032490)2.45078446
141regulation of glucose import in response to insulin stimulus (GO:2001273)2.44475564
142modulation by symbiont of host cellular process (GO:0044068)2.44417113
143semaphorin-plexin signaling pathway (GO:0071526)2.42221840
144positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.41508953
145hyaluronan catabolic process (GO:0030214)2.40643928
146urea metabolic process (GO:0019627)2.38423640
147regulation of type I interferon-mediated signaling pathway (GO:0060338)2.38415616
148detection of biotic stimulus (GO:0009595)2.37739496
149NIK/NF-kappaB signaling (GO:0038061)2.33835007
150regulation of dendritic cell antigen processing and presentation (GO:0002604)2.33491966
151regulation of extracellular matrix organization (GO:1903053)2.32790229
152peptide catabolic process (GO:0043171)2.31386096
153cell-substrate junction assembly (GO:0007044)2.31227985
154macrophage activation involved in immune response (GO:0002281)2.30519336
155adhesion of symbiont to host (GO:0044406)2.29971011
156pentose-phosphate shunt (GO:0006098)2.29717009
157thymic T cell selection (GO:0045061)2.29666571
158complement activation, alternative pathway (GO:0006957)2.29253712
159modulation by virus of host process (GO:0019054)2.24746853
160positive regulation of phagocytosis (GO:0050766)2.24500263
161negative regulation of interleukin-8 production (GO:0032717)2.24057358
162adherens junction assembly (GO:0034333)2.22994002
163positive regulation of blood vessel endothelial cell migration (GO:0043536)2.22260692
164positive regulation of triglyceride lipase activity (GO:0061365)2.20515438
165positive regulation of lipoprotein lipase activity (GO:0051006)2.20515438
166glycosphingolipid catabolic process (GO:0046479)2.20177264
167cell-substrate adherens junction assembly (GO:0007045)2.19825825
168focal adhesion assembly (GO:0048041)2.19825825
169regulation of phagocytosis (GO:0050764)2.19550481
170regulation of interferon-beta biosynthetic process (GO:0045357)2.19096674
171nitrogen cycle metabolic process (GO:0071941)2.16766541
172epithelial cell differentiation involved in prostate gland development (GO:0060742)2.15866944
173regulation of T-helper 2 cell differentiation (GO:0045628)2.15695573
174skin morphogenesis (GO:0043589)2.14729080
175positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.14076258
176regulation of cholesterol biosynthetic process (GO:0045540)2.13618193
177negative regulation of type 2 immune response (GO:0002829)2.13159777
178glucose catabolic process (GO:0006007)2.13029335
179vascular endothelial growth factor signaling pathway (GO:0038084)2.12619605
180regulation of apoptotic cell clearance (GO:2000425)2.12597467
181activation of JUN kinase activity (GO:0007257)2.12455896
182regulation of monocyte differentiation (GO:0045655)2.10372595
183negative regulation of viral release from host cell (GO:1902187)2.10219063
184lipopolysaccharide-mediated signaling pathway (GO:0031663)2.08906702
185regulation of mast cell degranulation (GO:0043304)2.08824208

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse2.68454165
2* LXR_22292898_ChIP-Seq_THP-1_Human2.50073007
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.49137073
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.47791832
5PPARA_22158963_ChIP-Seq_LIVER_Mouse2.43791856
6* VDR_21846776_ChIP-Seq_THP-1_Human2.33158811
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.28057282
8ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.26472414
9MYC_22102868_ChIP-Seq_BL_Human2.23639047
10* VDR_24763502_ChIP-Seq_THP-1_Human2.15654804
11KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.07680022
12KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.07680022
13KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.07680022
14STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.06340406
15LXR_22158963_ChIP-Seq_LIVER_Mouse2.05046661
16ZNF263_19887448_ChIP-Seq_K562_Human2.04670612
17SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.04445472
18SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.03107045
19RACK7_27058665_Chip-Seq_MCF-7_Human1.98928025
20TP63_17297297_ChIP-ChIP_HaCaT_Human1.96297928
21KDM2B_26808549_Chip-Seq_SUP-B15_Human1.86632535
22IRF8_22096565_ChIP-ChIP_GC-B_Human1.85801270
23KDM2B_26808549_Chip-Seq_DND41_Human1.83456071
24ELK3_25401928_ChIP-Seq_HUVEC_Human1.82062192
25* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.81348052
26TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78304133
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.77060718
28KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.76333711
29CLOCK_20551151_ChIP-Seq_293T_Human1.75239746
30TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.75062186
31KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.73004130
32* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.72506004
33NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.70167435
34FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.67366153
35STAT6_21828071_ChIP-Seq_BEAS2B_Human1.67143724
36ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.63864802
37MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.62885297
38ERG_21242973_ChIP-ChIP_JURKAT_Human1.61377617
39KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.61262135
40SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.60582664
41P300_27058665_Chip-Seq_ZR-75-30cells_Human1.59877833
42ZFP281_18757296_ChIP-ChIP_E14_Mouse1.59391084
43NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.57794924
44TCF7_22412390_ChIP-Seq_EML_Mouse1.55837819
45TRIM28_21343339_ChIP-Seq_HEK293_Human1.53832658
46BRD4_27068464_Chip-Seq_AML-cells_Mouse1.53538888
47TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.53280690
48RUNX1_22412390_ChIP-Seq_EML_Mouse1.52864184
49STAT3_1855785_ChIP-Seq_MESCs_Mouse1.51937985
50NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.51475033
51DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.50688548
52KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.50646253
53SA1_27219007_Chip-Seq_ERYTHROID_Human1.48387809
54NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.48095688
55SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.47778238
56RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.47707739
57RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.44840608
58KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.44804961
59SMC4_20622854_ChIP-Seq_HELA_Human1.43564184
60* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.43005287
61* MAF_26560356_Chip-Seq_TH2_Human1.41999195
62POU5F1_16518401_ChIP-PET_MESCs_Mouse1.40605161
63ZFP281_27345836_Chip-Seq_ESCs_Mouse1.40128515
64KDM2B_26808549_Chip-Seq_K562_Human1.39200661
65RARG_19884340_ChIP-ChIP_MEFs_Mouse1.39124147
66ESR2_21235772_ChIP-Seq_MCF-7_Human1.38714793
67POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.37882094
68EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.37642168
69VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36929224
70* TET1_21451524_ChIP-Seq_MESCs_Mouse1.34801482
71SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.34076262
72ATF3_27146783_Chip-Seq_COLON_Human1.33660850
73EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.33586420
74* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.32991596
75CREB1_26743006_Chip-Seq_LNCaP_Human1.30722390
76* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.30547491
77ELF1_20517297_ChIP-Seq_JURKAT_Human1.29774812
78BCL6_27268052_Chip-Seq_Bcells_Human1.29220948
79* GATA1_19941827_ChIP-Seq_MEL_Mouse1.28317619
80NANOG_21062744_ChIP-ChIP_HESCs_Human1.27018374
81RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.25820776
82RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24671600
83SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.23883391
84SCL_19346495_ChIP-Seq_HPC-7_Human1.23116436
85* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.20831707
86TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.20729231
87DNAJC2_21179169_ChIP-ChIP_NT2_Human1.20673647
88MYB_21317192_ChIP-Seq_ERMYB_Mouse1.19897468
89PU.1_20513432_ChIP-Seq_Bcells_Mouse1.19261358
90CTCF_21964334_ChIP-Seq_BJAB-B_Human1.19162108
91KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19011140
92SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.18310715
93KDM2B_26808549_Chip-Seq_JURKAT_Human1.18067682
94CTCF_27219007_Chip-Seq_ERYTHROID_Human1.17520977
95MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.17412320
96SPI1_23127762_ChIP-Seq_K562_Human1.17412293
97BP1_19119308_ChIP-ChIP_Hs578T_Human1.17299054
98TCF3_18692474_ChIP-Seq_MEFs_Mouse1.16925174
99HIF1A_21447827_ChIP-Seq_MCF-7_Human1.16452426
100EGR1_19374776_ChIP-ChIP_THP-1_Human1.16274146
101* TP53_22127205_ChIP-Seq_IMR90_Human1.15773968
102ESR1_15608294_ChIP-ChIP_MCF-7_Human1.15672997
103TCF3_18692474_ChIP-Seq_MESCs_Mouse1.15542354
104* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.13317060
105NCOR1_26117541_ChIP-Seq_K562_Human1.12646355
106NFIB_24661679_ChIP-Seq_LUNG_Mouse1.12140552
107BCOR_27268052_Chip-Seq_Bcells_Human1.12094457
108MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.11594644
109PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.11158101
110P68_20966046_ChIP-Seq_HELA_Human1.11064827
111RARB_24833708_ChIP-Seq_LIVER_Mouse1.11007231
112SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.09341961
113TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.09207693
114GATA1_19941826_ChIP-Seq_K562_Human1.09113739
115CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.09066392
116SRY_22984422_ChIP-ChIP_TESTIS_Rat1.07938969
117GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07728967
118RUNX1_27514584_Chip-Seq_MCF-7_Human1.07520061
119* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.07211651
120MAF_26560356_Chip-Seq_TH1_Human1.07081885
121UTX_26944678_Chip-Seq_JUKART_Human1.06349582
122NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.06258193
123PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06029895
124CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.06008977
125GATA1_22383799_ChIP-Seq_G1ME_Mouse1.05833362
126NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.04421009
127* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.04371926
128THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.03967528
129CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.03734203
130ESR1_21235772_ChIP-Seq_MCF-7_Human1.03311381
131SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.03262675
132ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.02881078
133IRF8_27001747_Chip-Seq_BMDM_Mouse1.02700380
134WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02225051
135RXRA_24833708_ChIP-Seq_LIVER_Mouse1.01499567
136ETS1_21867929_ChIP-Seq_TH2_Mouse1.01488802
137UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.01036870
138CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.00881022
139SMC1_22415368_ChIP-Seq_MEFs_Mouse1.00718270
140CHD1_26751641_Chip-Seq_LNCaP_Human1.00343976
141CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00208517
142TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99742139
143TP63_22573176_ChIP-Seq_HFKS_Human0.99667250
144GATA6_25053715_ChIP-Seq_YYC3_Human0.99159496

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003283_abnormal_digestive_organ3.77655619
2MP0009278_abnormal_bone_marrow3.16952597
3MP0003705_abnormal_hypodermis_morpholog3.10177647
4MP0003436_decreased_susceptibility_to2.86314332
5MP0002877_abnormal_melanocyte_morpholog2.75302111
6MP0005365_abnormal_bile_salt2.70567221
7MP0004233_abnormal_muscle_weight2.68428775
8MP0008438_abnormal_cutaneous_collagen2.40937101
9MP0003303_peritoneal_inflammation2.33412307
10MP0005076_abnormal_cell_differentiation2.28160631
11MP0005058_abnormal_lysosome_morphology2.27197672
12MP0010352_gastrointestinal_tract_polyps2.21085996
13MP0005451_abnormal_body_composition2.16101825
14MP0005085_abnormal_gallbladder_physiolo2.12862777
15MP0001958_emphysema2.11115848
16MP0010030_abnormal_orbit_morphology2.09682103
17MP0003172_abnormal_lysosome_physiology2.03710577
18MP0004858_abnormal_nervous_system2.03225937
19MP0003300_gastrointestinal_ulcer1.96464109
20MP0008260_abnormal_autophagy1.94824925
21MP0008057_abnormal_DNA_replication1.93667129
22MP0005171_absent_coat_pigmentation1.90156826
23MP0002139_abnormal_hepatobiliary_system1.87375009
24MP0005409_darkened_coat_color1.86419266
25MP0003566_abnormal_cell_adhesion1.84605766
26MP0004185_abnormal_adipocyte_glucose1.84061482
27MP0004264_abnormal_extraembryonic_tissu1.83808457
28MP0003091_abnormal_cell_migration1.75629457
29MP0005220_abnormal_exocrine_pancreas1.75316947
30MP0003045_fibrosis1.72088458
31MP0000858_altered_metastatic_potential1.65138530
32MP0002419_abnormal_innate_immunity1.64237258
33MP0003724_increased_susceptibility_to1.63801668
34MP0001533_abnormal_skeleton_physiology1.60796669
35MP0002009_preneoplasia1.60687966
36MP0005025_abnormal_response_to1.58392340
37MP0001835_abnormal_antigen_presentation1.56522620
38MP0004947_skin_inflammation1.53110134
39MP0005464_abnormal_platelet_physiology1.49782265
40MP0002269_muscular_atrophy1.48066182
41MP0003119_abnormal_digestive_system1.43130369
42MP0005257_abnormal_intraocular_pressure1.42789946
43MP0003453_abnormal_keratinocyte_physiol1.42578269
44MP0000013_abnormal_adipose_tissue1.41316988
45MP0004272_abnormal_basement_membrane1.40044463
46MP0005360_urolithiasis1.39473008
47MP0000371_diluted_coat_color1.38555368
48MP0003252_abnormal_bile_duct1.37772287
49MP0001790_abnormal_immune_system1.37134793
50MP0005387_immune_system_phenotype1.37134793
51MP0000003_abnormal_adipose_tissue1.36739191
52MP0002998_abnormal_bone_remodeling1.36130573
53MP0009840_abnormal_foam_cell1.35372172
54MP0000462_abnormal_digestive_system1.33114417
55MP0006082_CNS_inflammation1.32590655
56MP0002060_abnormal_skin_morphology1.31499180
57MP0003329_amyloid_beta_deposits1.30517558
58MP0005666_abnormal_adipose_tissue1.30070872
59MP0004130_abnormal_muscle_cell1.29230526
60MP0005000_abnormal_immune_tolerance1.28802721
61MP0001666_abnormal_nutrient_absorption1.28350927
62MP0010155_abnormal_intestine_physiology1.28155012
63MP0003890_abnormal_embryonic-extraembry1.27774477
64MP0005375_adipose_tissue_phenotype1.27729372
65MP0002909_abnormal_adrenal_gland1.26282416
66MP0000767_abnormal_smooth_muscle1.24558040
67MP0001944_abnormal_pancreas_morphology1.23978708
68MP0000604_amyloidosis1.23210619
69MP0003828_pulmonary_edema1.20363255
70MP0005397_hematopoietic_system_phenotyp1.19777976
71MP0001545_abnormal_hematopoietic_system1.19777976
72MP0003763_abnormal_thymus_physiology1.19180335
73MP0005670_abnormal_white_adipose1.18806333
74MP0002933_joint_inflammation1.17846519
75MP0002086_abnormal_extraembryonic_tissu1.17225088
76MP0005083_abnormal_biliary_tract1.17211469
77MP0005275_abnormal_skin_tensile1.16102611
78MP0000609_abnormal_liver_physiology1.15261960
79MP0005023_abnormal_wound_healing1.14817470
80MP0003183_abnormal_peptide_metabolism1.14268486
81MP0004197_abnormal_fetal_growth/weight/1.11131308
82MP0002166_altered_tumor_susceptibility1.10743840
83MP0002896_abnormal_bone_mineralization1.10072556
84MP0003075_altered_response_to1.08929539
85MP0009785_altered_susceptibility_to1.08728089
86MP0002452_abnormal_antigen_presenting1.08491413
87MP0000639_abnormal_adrenal_gland1.08298649
88MP0001800_abnormal_humoral_immune1.08090088
89MP0002420_abnormal_adaptive_immunity1.06153685
90MP0002723_abnormal_immune_serum1.06118674
91MP0001819_abnormal_immune_cell1.05756330
92MP0003191_abnormal_cellular_cholesterol1.05704838
93MP0009384_cardiac_valve_regurgitation1.05622692
94MP0010234_abnormal_vibrissa_follicle1.04966596
95MP0002693_abnormal_pancreas_physiology1.04940547
96MP0005390_skeleton_phenotype1.04643875
97MP0008961_abnormal_basal_metabolism1.03782317
98MP0009333_abnormal_splenocyte_physiolog1.03475456
99MP0005503_abnormal_tendon_morphology1.01926705
100MP0009115_abnormal_fat_cell1.01136883
101MP0000465_gastrointestinal_hemorrhage0.99861143
102MP0010329_abnormal_lipoprotein_level0.99102660
103MP0002078_abnormal_glucose_homeostasis0.98158664
104MP0003448_altered_tumor_morphology0.97097243
105MP0002084_abnormal_developmental_patter0.96594180
106MP0001845_abnormal_inflammatory_respons0.95798460
107MP0006054_spinal_hemorrhage0.95769047
108MP0002148_abnormal_hypersensitivity_rea0.95165967
109MP0002970_abnormal_white_adipose0.94826816
110MP0008469_abnormal_protein_level0.93812043
111MP0003195_calcinosis0.93673983
112MP0002118_abnormal_lipid_homeostasis0.93585694
113MP0002396_abnormal_hematopoietic_system0.92757318
114MP0002796_impaired_skin_barrier0.92682720
115MP0005164_abnormal_response_to0.92608992
116MP0004510_myositis0.91828494
117MP0010630_abnormal_cardiac_muscle0.91372570
118MP0004133_heterotaxia0.90770828
119MP0001873_stomach_inflammation0.90205339
120MP0002405_respiratory_system_inflammati0.90174275
121MP0000470_abnormal_stomach_morphology0.88655185
122MP0000579_abnormal_nail_morphology0.88596894
123MP0009643_abnormal_urine_homeostasis0.88505324
124MP0001697_abnormal_embryo_size0.87452257
125MP0006072_abnormal_retinal_apoptosis0.86852042
126MP0000249_abnormal_blood_vessel0.86573825
127MP0000751_myopathy0.86507667
128MP0003959_abnormal_lean_body0.85925416
129MP0001851_eye_inflammation0.85859367
130MP0004883_abnormal_blood_vessel0.85077857
131MP0010368_abnormal_lymphatic_system0.84645889
132MP0004381_abnormal_hair_follicle0.84292294
133MP0005330_cardiomyopathy0.83736044
134MP0005508_abnormal_skeleton_morphology0.83191681
135MP0004808_abnormal_hematopoietic_stem0.82351881
136MP0003866_abnormal_defecation0.82310544
137MP0002111_abnormal_tail_morphology0.82294643
138MP0002168_other_aberrant_phenotype0.82055067
139MP0005319_abnormal_enzyme/_coenzyme0.81224455
140MP0000716_abnormal_immune_system0.80924783
141MP0005332_abnormal_amino_acid0.80637525
142MP0000678_abnormal_parathyroid_gland0.80634769
143MP0002282_abnormal_trachea_morphology0.80372887
144MP0000598_abnormal_liver_morphology0.80372154
145MP0002653_abnormal_ependyma_morphology0.79686972
146MP0001849_ear_inflammation0.79550435
147MP0005166_decreased_susceptibility_to0.79412253
148MP0000681_abnormal_thyroid_gland0.78743017
149MP0002398_abnormal_bone_marrow0.77756867
150MP0002971_abnormal_brown_adipose0.77484596
151MP0004043_abnormal_pH_regulation0.77287672
152MP0009780_abnormal_chondrocyte_physiolo0.76894962
153MP0002085_abnormal_embryonic_tissue0.76525612
154MP0002132_abnormal_respiratory_system0.75145988
155MP0003279_aneurysm0.71662499
156MP0010307_abnormal_tumor_latency0.71056607
157MP0001672_abnormal_embryogenesis/_devel0.70086220
158MP0005380_embryogenesis_phenotype0.70086220
159MP0004087_abnormal_muscle_fiber0.69025963
160MP0000685_abnormal_immune_system0.68796838
161MP0003656_abnormal_erythrocyte_physiolo0.68324796
162MP0008995_early_reproductive_senescence0.67743494
163MP0002108_abnormal_muscle_morphology0.67351912
164MP0004019_abnormal_vitamin_homeostasis0.67317689
165MP0002837_dystrophic_cardiac_calcinosis0.66650208

Predicted human phenotypes

RankGene SetZ-score
1Mucopolysacchariduria (HP:0008155)4.58375254
2Urinary glycosaminoglycan excretion (HP:0003541)4.58375254
3Turricephaly (HP:0000262)4.42851280
4Cerebral aneurysm (HP:0004944)4.37663067
5Abnormality of mucopolysaccharide metabolism (HP:0011020)4.17290636
6Abnormality of polysaccharide metabolism (HP:0011012)4.17290636
7Abnormality of glycosaminoglycan metabolism (HP:0004371)4.17290636
8Dysostosis multiplex (HP:0000943)4.06899389
9Ulnar bowing (HP:0003031)3.89443367
10Pancreatic islet-cell hyperplasia (HP:0004510)3.75763585
11Large for gestational age (HP:0001520)3.62381432
12Ketoacidosis (HP:0001993)3.39956927
13Abnormality of the pancreatic islet cells (HP:0006476)3.36364956
14Abnormality of endocrine pancreas physiology (HP:0012093)3.36364956
15Alopecia of scalp (HP:0002293)3.29770804
16Asymmetric septal hypertrophy (HP:0001670)3.19790271
17Eczematoid dermatitis (HP:0000976)3.17136021
18Pustule (HP:0200039)3.11485059
19Hemorrhage of the eye (HP:0011885)3.03197956
20Systemic lupus erythematosus (HP:0002725)3.01612686
21Vertebral compression fractures (HP:0002953)2.95685614
22Hyperinsulinemic hypoglycemia (HP:0000825)2.93809995
23Rib fusion (HP:0000902)2.93399003
24Thin bony cortex (HP:0002753)2.93281842
25Hypoglycemic coma (HP:0001325)2.87107312
26Joint stiffness (HP:0001387)2.82481126
27Facial hemangioma (HP:0000329)2.79776025
28Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.71017053
29Vertebral hypoplasia (HP:0008417)2.71017053
30Polycythemia (HP:0001901)2.70097970
31Male infertility (HP:0003251)2.70079090
32Growth hormone excess (HP:0000845)2.69417316
33Abnormality of complement system (HP:0005339)2.68100734
34Protrusio acetabuli (HP:0003179)2.67789701
35Hypercortisolism (HP:0001578)2.65262954
36Hypochromic microcytic anemia (HP:0004840)2.61713831
37Annular pancreas (HP:0001734)2.60666071
38Coronal craniosynostosis (HP:0004440)2.59868646
39Abnormality of glycolipid metabolism (HP:0010969)2.55526119
40Abnormality of liposaccharide metabolism (HP:0010968)2.55526119
41Abnormality of glycosphingolipid metabolism (HP:0004343)2.55526119
42Abnormality of macrophages (HP:0004311)2.51351721
43Hypoglycemic seizures (HP:0002173)2.48777381
44Ketosis (HP:0001946)2.48230965
45Abnormal hemoglobin (HP:0011902)2.47566475
46Bowed forearm bones (HP:0003956)2.47501613
47Bowing of the arm (HP:0006488)2.47501613
48Broad face (HP:0000283)2.46576680
49Orthostatic hypotension (HP:0001278)2.44721130
50Cellulitis (HP:0100658)2.42491729
51Short humerus (HP:0005792)2.42337436
52Premature rupture of membranes (HP:0001788)2.38622951
53Aneurysm (HP:0002617)2.37540310
54Myocardial infarction (HP:0001658)2.35730882
55Recurrent gram-negative bacterial infections (HP:0005420)2.33566010
56Complement deficiency (HP:0004431)2.33394619
57Concave nail (HP:0001598)2.32633650
58Recurrent abscess formation (HP:0002722)2.32028302
59Premature skin wrinkling (HP:0100678)2.29577072
60Increased cerebral lipofuscin (HP:0011813)2.28127501
61Poikiloderma (HP:0001029)2.27486701
62Peritonitis (HP:0002586)2.26344194
63Vaginal fistula (HP:0004320)2.25294104
64Muscle fibrillation (HP:0010546)2.24853009
65Dilatation of the ascending aorta (HP:0005111)2.24363139
66Congenital hip dislocation (HP:0001374)2.21612397
67Hyperacusis (HP:0010780)2.20379279
68Congenital glaucoma (HP:0001087)2.18265140
69Generalized amyotrophy (HP:0003700)2.15805067
70Gingivitis (HP:0000230)2.14975899
71Dysautonomia (HP:0002459)2.14613103
72Metaphyseal cupping (HP:0003021)2.13744057
73Atrophic scars (HP:0001075)2.13462540
74Recurrent bacterial skin infections (HP:0005406)2.13459813
75Fragile skin (HP:0001030)2.13320215
76Emphysema (HP:0002097)2.12784388
77Increased variability in muscle fiber diameter (HP:0003557)2.12382173
78Tongue fasciculations (HP:0001308)2.11684817
79Aortic aneurysm (HP:0004942)2.10961924
80Late onset (HP:0003584)2.10781033
81Increased CSF protein (HP:0002922)2.10694082
82Aplasia/hypoplasia of the humerus (HP:0006507)2.10217566
83Purpura (HP:0000979)2.09423288
84Rectal fistula (HP:0100590)2.09120996
85Rectovaginal fistula (HP:0000143)2.09120996
86Hypertriglyceridemia (HP:0002155)2.08320765
87Interstitial pulmonary disease (HP:0006530)2.08266960
88Achilles tendon contracture (HP:0001771)2.07826433
89Biconcave vertebral bodies (HP:0004586)2.06636457
90Flat acetabular roof (HP:0003180)2.04767349
91Hand muscle atrophy (HP:0009130)2.04488885
92Hyperglycemia (HP:0003074)2.04345533
93Malnutrition (HP:0004395)2.04270599
94J-shaped sella turcica (HP:0002680)2.03993052
95Wormian bones (HP:0002645)2.02575597
96Myositis (HP:0100614)2.02174068
97Aortic dissection (HP:0002647)2.01580125
98Abnormality of the Achilles tendon (HP:0005109)2.01292047
99Intestinal fistula (HP:0100819)2.01161937
100Disproportionate tall stature (HP:0001519)2.00955601
101Amyloidosis (HP:0011034)2.00799801
102Abnormality of the thoracic spine (HP:0100711)2.00361302
103Obstructive sleep apnea (HP:0002870)1.99969964
104Vascular tortuosity (HP:0004948)1.99907346
105Anteriorly placed anus (HP:0001545)1.99615134
106Back pain (HP:0003418)1.97687420
107Hypoplastic ischia (HP:0003175)1.97587841
108Increased neuronal autofluorescent lipopigment (HP:0002074)1.97571795
109Thoracic kyphosis (HP:0002942)1.96656853
110Abnormality of monocarboxylic acid metabolism (HP:0010996)1.96575803
111Loss of speech (HP:0002371)1.94750856
112Polygenic inheritance (HP:0010982)1.94609246
113Abnormality of aromatic amino acid family metabolism (HP:0004338)1.94517987
114Exocrine pancreatic insufficiency (HP:0001738)1.92941524
115Coarse hair (HP:0002208)1.92452989
116Stridor (HP:0010307)1.92084857
117Glomerulonephritis (HP:0000099)1.91695532
118Increased IgM level (HP:0003496)1.91327183
119Diaphragmatic weakness (HP:0009113)1.91010939
120Mitral regurgitation (HP:0001653)1.90591705
121Insulin resistance (HP:0000855)1.90516785
122Joint hemorrhage (HP:0005261)1.90281389
123Arterial tortuosity (HP:0005116)1.89273625
124Spondylolisthesis (HP:0003302)1.89200998
125Hyperparathyroidism (HP:0000843)1.88845309
126Blue sclerae (HP:0000592)1.88811739
127Upper limb amyotrophy (HP:0009129)1.88266135
128Distal upper limb amyotrophy (HP:0007149)1.88266135
129Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.87865463
130Gastrointestinal inflammation (HP:0004386)1.87668105
131Deep venous thrombosis (HP:0002625)1.87308579
132Increased IgE level (HP:0003212)1.85993700
133Choanal stenosis (HP:0000452)1.85139619
134Distal lower limb muscle weakness (HP:0009053)1.84412492
135Abnormality of the nasal mucosa (HP:0000433)1.84370576
136Epistaxis (HP:0000421)1.83140568
137Distal lower limb amyotrophy (HP:0008944)1.82696559
138Bladder diverticulum (HP:0000015)1.82484106
139Xanthomatosis (HP:0000991)1.82030860
140Intrahepatic cholestasis (HP:0001406)1.80350227
141Abnormality of skeletal muscle fiber size (HP:0012084)1.80321022
142Lower limb hyperreflexia (HP:0002395)1.79622932
143Abnormality of the intrinsic pathway (HP:0010989)1.78535332
144Spontaneous hematomas (HP:0007420)1.77813375
145Abnormality of the ischium (HP:0003174)1.77566188
146Albinism (HP:0001022)1.76740373
147Obstructive lung disease (HP:0006536)1.76562147
148Chronic obstructive pulmonary disease (HP:0006510)1.76562147
149Abnormal enzyme/coenzyme activity (HP:0012379)1.76138872
150Shallow orbits (HP:0000586)1.76071727
151Abnormality of alkaline phosphatase activity (HP:0004379)1.75592218
152Insulin-resistant diabetes mellitus (HP:0000831)1.74780967
153Symptomatic seizures (HP:0011145)1.74685081
154Short chin (HP:0000331)1.73612866
155Myoglobinuria (HP:0002913)1.73589418
156Gastrointestinal infarctions (HP:0005244)1.72849788
157Mitral stenosis (HP:0001718)1.72777314
158Spinal rigidity (HP:0003306)1.72756831
159Gastrointestinal dysmotility (HP:0002579)1.72592997
160Abnormality of the lower motor neuron (HP:0002366)1.71371520
161Ankle contracture (HP:0006466)1.70691680
162Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.69851267
163Mitral valve prolapse (HP:0001634)1.69683855
164Nephritis (HP:0000123)1.69682784
165Macroorchidism (HP:0000053)1.69455324
166Prolonged bleeding time (HP:0003010)1.69407537
167Alacrima (HP:0000522)1.67122758
168Genu recurvatum (HP:0002816)1.66325260
169Cervical subluxation (HP:0003308)1.65959975
170Hamartoma (HP:0010566)1.65426591
171Mildly elevated creatine phosphokinase (HP:0008180)1.65137178
172Increased connective tissue (HP:0009025)1.65007340
173Mediastinal lymphadenopathy (HP:0100721)1.63951666
174Inflammation of the large intestine (HP:0002037)1.63345646
175Colitis (HP:0002583)1.62748623

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK4.68419400
2MAPK154.47888467
3DDR24.13982026
4TRIB33.68166011
5PDGFRA2.96838641
6PRPF4B2.88135263
7MAP3K62.81045809
8ERN12.71569725
9SMG12.45868089
10MAP3K112.38492282
11TYRO32.19463134
12MATK2.04161255
13PKN22.01123418
14BMX1.97051063
15DYRK1B1.96156819
16PRKD21.91054642
17MAP3K101.90322240
18CSK1.84266926
19SIK11.82968693
20PINK11.74386365
21IRAK31.73479590
22TYK21.68291195
23FGR1.65295520
24UHMK11.57472476
25RIPK41.56380083
26TBK11.55509989
27RIPK11.46922130
28BCKDK1.39356033
29HIPK21.34543647
30FLT31.34309693
31BLK1.34184713
32DAPK11.32069605
33EEF2K1.31331432
34MAP3K131.30052997
35MST1R1.29958462
36CDK61.25484214
37SCYL21.22651060
38INSRR1.20995193
39GRK61.20899498
40PTK61.19922542
41TAOK31.19153408
42JAK31.17645197
43MTOR1.17089949
44CDC42BPA1.17022268
45TRPM71.16228890
46LATS11.13622539
47TESK11.13191102
48PIM21.12314178
49GSK3A1.10735537
50IRAK41.09783764
51RPS6KA21.08714582
52NME21.07702981
53MAP3K141.06293373
54TNK21.04823722
55TAOK21.04726211
56PDPK11.02982080
57KIT1.01231891
58PTK21.00729024
59PASK1.00457366
60TESK20.99973753
61LATS20.99039121
62MAPK110.95998649
63TTN0.94667149
64RPS6KC10.93720193
65RPS6KL10.93720193
66CDK120.91326140
67FGFR40.88988635
68CSF1R0.88985391
69FES0.88786925
70PDGFRB0.87099727
71CDK70.86580648
72RPS6KA60.80501719
73PRKAA10.78938714
74BTK0.77885202
75AKT30.77578766
76PIM10.75844868
77PHKG10.74940226
78PHKG20.74940226
79MAPKAPK30.73528093
80PAK20.70246094
81EPHB10.69715168
82KSR20.65602351
83MAPK120.65532817
84YES10.64084950
85SIK20.64007206
86IKBKE0.63434985
87HCK0.62311518
88MAPK70.61887044
89JAK20.61737615
90FGFR30.61574765
91MET0.60983338
92ARAF0.60823612
93LMTK20.60273052
94PRKG20.59950044
95PDK10.59931485
96PAK40.59446011
97NEK90.58848477
98DMPK0.58550377
99EPHA20.57830729
100FRK0.57801834
101MAP3K70.57490871
102PRKD30.56970922
103RPS6KA10.55822803
104KDR0.55583497
105TAOK10.55575376
106PRKD10.55076894
107TGFBR20.53323471
108ALK0.52370034
109CDK40.51758621
110LRRK20.51291222
111IRAK20.51103874
112CAMK1D0.47977272
113MAP2K20.47750362
114EGFR0.47136449
115STK380.45011166
116PRKAA20.44659460
117NTRK10.44059717
118SYK0.43775147
119MAP3K80.43669992
120MOS0.41275577
121STK30.40561246
122MAP3K10.38502483
123RPS6KB20.38112444
124MARK20.37314505
125PRKCH0.36557139
126MAP3K20.35993818
127STK100.35027759
128FER0.34609152
129RET0.33939929
130MAP3K30.33876246
131MAP4K10.32195869
132MAPK10.31909320
133FGFR10.31767675
134INSR0.31344188
135MAPK30.29963534
136EPHA30.28724554
137ZAP700.27265712
138DYRK30.24512894
139MAP2K30.23296154
140JAK10.23078431
141RPS6KB10.21352827
142PRKACG0.20498880
143MAPKAPK20.20361996
144CAMK1G0.19989675

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.46305899
2Fatty acid biosynthesis_Homo sapiens_hsa000613.83778522
3Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.42768181
4Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.27158602
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.26379122
6Fatty acid metabolism_Homo sapiens_hsa012122.09219447
7mTOR signaling pathway_Homo sapiens_hsa041502.08873255
8Glycosaminoglycan degradation_Homo sapiens_hsa005311.98803405
9Lysine degradation_Homo sapiens_hsa003101.94088726
10Staphylococcus aureus infection_Homo sapiens_hsa051501.78300609
11Arginine biosynthesis_Homo sapiens_hsa002201.76084000
12Osteoclast differentiation_Homo sapiens_hsa043801.72588065
13Bladder cancer_Homo sapiens_hsa052191.68126726
14Leishmaniasis_Homo sapiens_hsa051401.60061553
15B cell receptor signaling pathway_Homo sapiens_hsa046621.57630875
16Arginine and proline metabolism_Homo sapiens_hsa003301.52850708
17Adherens junction_Homo sapiens_hsa045201.52316517
18Notch signaling pathway_Homo sapiens_hsa043301.49959945
19Selenocompound metabolism_Homo sapiens_hsa004501.49611510
20Longevity regulating pathway - mammal_Homo sapiens_hsa042111.47210586
21Cyanoamino acid metabolism_Homo sapiens_hsa004601.47159357
22Biosynthesis of amino acids_Homo sapiens_hsa012301.45328173
23Pentose and glucuronate interconversions_Homo sapiens_hsa000401.41679423
24Fat digestion and absorption_Homo sapiens_hsa049751.41110127
25Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.41050346
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.40688251
27Nitrogen metabolism_Homo sapiens_hsa009101.39130713
28Base excision repair_Homo sapiens_hsa034101.38901280
29Tryptophan metabolism_Homo sapiens_hsa003801.36421646
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34815354
31Fatty acid degradation_Homo sapiens_hsa000711.32647372
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.32333989
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.31508732
34Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.23959167
35Leukocyte transendothelial migration_Homo sapiens_hsa046701.23245937
36Toxoplasmosis_Homo sapiens_hsa051451.23081720
37Toll-like receptor signaling pathway_Homo sapiens_hsa046201.19723576
38Folate biosynthesis_Homo sapiens_hsa007901.18722507
39Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.17286650
40Sulfur relay system_Homo sapiens_hsa041221.16375717
41Hippo signaling pathway_Homo sapiens_hsa043901.15201048
42AMPK signaling pathway_Homo sapiens_hsa041521.14472626
43Non-small cell lung cancer_Homo sapiens_hsa052231.13808468
44Circadian rhythm_Homo sapiens_hsa047101.13507375
45Lysosome_Homo sapiens_hsa041421.13454846
46Chronic myeloid leukemia_Homo sapiens_hsa052201.13201674
47N-Glycan biosynthesis_Homo sapiens_hsa005101.11230586
48Pertussis_Homo sapiens_hsa051331.11121691
49Hepatitis C_Homo sapiens_hsa051601.09720557
50Insulin resistance_Homo sapiens_hsa049311.09260382
51Tuberculosis_Homo sapiens_hsa051521.06576784
52Pentose phosphate pathway_Homo sapiens_hsa000301.05410924
53Malaria_Homo sapiens_hsa051441.04666380
54Focal adhesion_Homo sapiens_hsa045101.03797781
55TNF signaling pathway_Homo sapiens_hsa046681.02183827
56Insulin signaling pathway_Homo sapiens_hsa049101.01593663
57Primary bile acid biosynthesis_Homo sapiens_hsa001201.00892291
58Galactose metabolism_Homo sapiens_hsa000520.98951292
59Influenza A_Homo sapiens_hsa051640.97861097
60ABC transporters_Homo sapiens_hsa020100.97623596
61Starch and sucrose metabolism_Homo sapiens_hsa005000.97250312
62Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.96395974
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.96377537
64Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.96319557
65Protein digestion and absorption_Homo sapiens_hsa049740.94308109
66Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93995631
67Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.93059147
68VEGF signaling pathway_Homo sapiens_hsa043700.92567571
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.92192663
70Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.92130306
71Hedgehog signaling pathway_Homo sapiens_hsa043400.91725058
72Mismatch repair_Homo sapiens_hsa034300.90190256
73PPAR signaling pathway_Homo sapiens_hsa033200.88787987
74Fructose and mannose metabolism_Homo sapiens_hsa000510.88545523
75Sulfur metabolism_Homo sapiens_hsa009200.84760055
76Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.83713229
77Hepatitis B_Homo sapiens_hsa051610.83321532
78Propanoate metabolism_Homo sapiens_hsa006400.83222060
79NF-kappa B signaling pathway_Homo sapiens_hsa040640.82566677
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.82271858
81Type II diabetes mellitus_Homo sapiens_hsa049300.81558152
82Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81492172
83Platelet activation_Homo sapiens_hsa046110.81307620
84Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.80837674
85Small cell lung cancer_Homo sapiens_hsa052220.80463807
86Phenylalanine metabolism_Homo sapiens_hsa003600.77599856
87Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77246755
88Phagosome_Homo sapiens_hsa041450.76627651
89Acute myeloid leukemia_Homo sapiens_hsa052210.76094912
90Renal cell carcinoma_Homo sapiens_hsa052110.76008680
91Proteoglycans in cancer_Homo sapiens_hsa052050.75517202
92Endocytosis_Homo sapiens_hsa041440.74389023
93Allograft rejection_Homo sapiens_hsa053300.73285902
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73088327
95Autoimmune thyroid disease_Homo sapiens_hsa053200.73042077
96Apoptosis_Homo sapiens_hsa042100.73012835
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.72151297
98Glucagon signaling pathway_Homo sapiens_hsa049220.71964337
99TGF-beta signaling pathway_Homo sapiens_hsa043500.71948455
100Bile secretion_Homo sapiens_hsa049760.71034879
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.69947254
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.69087604
103Endometrial cancer_Homo sapiens_hsa052130.67914307
104Salmonella infection_Homo sapiens_hsa051320.67281221
105Hematopoietic cell lineage_Homo sapiens_hsa046400.67197743
106Glycerolipid metabolism_Homo sapiens_hsa005610.66570126
107GnRH signaling pathway_Homo sapiens_hsa049120.66246568
108Chemokine signaling pathway_Homo sapiens_hsa040620.65141716
109Measles_Homo sapiens_hsa051620.63973176
110Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.63625855
111Thyroid cancer_Homo sapiens_hsa052160.62637672
112T cell receptor signaling pathway_Homo sapiens_hsa046600.62411194
113Adipocytokine signaling pathway_Homo sapiens_hsa049200.62330566
114Graft-versus-host disease_Homo sapiens_hsa053320.62024478
115Herpes simplex infection_Homo sapiens_hsa051680.60279885
116Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.59370139
117Choline metabolism in cancer_Homo sapiens_hsa052310.59088341
118ECM-receptor interaction_Homo sapiens_hsa045120.58930874
119Inositol phosphate metabolism_Homo sapiens_hsa005620.58732522
120Intestinal immune network for IgA production_Homo sapiens_hsa046720.58535542
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58222967
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.58169765
123Phosphatidylinositol signaling system_Homo sapiens_hsa040700.57943070
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.57164337
125MicroRNAs in cancer_Homo sapiens_hsa052060.56736303
126Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.56539091
127Complement and coagulation cascades_Homo sapiens_hsa046100.56134947
128Dorso-ventral axis formation_Homo sapiens_hsa043200.55937398
129Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.55847789
130Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55807390
131Pancreatic cancer_Homo sapiens_hsa052120.55764669
132Estrogen signaling pathway_Homo sapiens_hsa049150.55609307
133Jak-STAT signaling pathway_Homo sapiens_hsa046300.55251117
134Carbon metabolism_Homo sapiens_hsa012000.55216891
135Prion diseases_Homo sapiens_hsa050200.54756208
136Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54004007
137HTLV-I infection_Homo sapiens_hsa051660.53606522
138Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.52995428
139Antigen processing and presentation_Homo sapiens_hsa046120.52786965
140Butanoate metabolism_Homo sapiens_hsa006500.52691037
141Sphingolipid metabolism_Homo sapiens_hsa006000.51476204
142Glioma_Homo sapiens_hsa052140.51147326
143Glycerophospholipid metabolism_Homo sapiens_hsa005640.51012383
144Prolactin signaling pathway_Homo sapiens_hsa049170.50719013
145Prostate cancer_Homo sapiens_hsa052150.50378742
146Tight junction_Homo sapiens_hsa045300.50171188
147Viral myocarditis_Homo sapiens_hsa054160.49994949
148Colorectal cancer_Homo sapiens_hsa052100.49191890
149AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.48091410
150Other glycan degradation_Homo sapiens_hsa005110.47821770
151Pyruvate metabolism_Homo sapiens_hsa006200.47617041
152Basal cell carcinoma_Homo sapiens_hsa052170.47039632
153PI3K-Akt signaling pathway_Homo sapiens_hsa041510.46460193
154p53 signaling pathway_Homo sapiens_hsa041150.45427243
155Wnt signaling pathway_Homo sapiens_hsa043100.45085815
156Shigellosis_Homo sapiens_hsa051310.44074801
157Amoebiasis_Homo sapiens_hsa051460.42632773
158Renin-angiotensin system_Homo sapiens_hsa046140.42495421

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