SLC44A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)9.53680123
2axon ensheathment in central nervous system (GO:0032291)9.53680123
3fatty acid elongation (GO:0030497)6.94888324
4ensheathment of neurons (GO:0007272)6.37032716
5axon ensheathment (GO:0008366)6.37032716
6myelination (GO:0042552)6.33826071
7cholesterol biosynthetic process (GO:0006695)5.16622096
8long-chain fatty acid biosynthetic process (GO:0042759)5.09508843
9myelin maintenance (GO:0043217)4.85899858
10negative regulation of neurotransmitter secretion (GO:0046929)4.84231809
11sterol biosynthetic process (GO:0016126)4.53501080
12regulation of collateral sprouting (GO:0048670)4.47738219
13L-amino acid import (GO:0043092)4.46430296
14glycosphingolipid biosynthetic process (GO:0006688)4.33911073
15locomotory exploration behavior (GO:0035641)4.30961780
16virion attachment to host cell (GO:0019062)4.17608833
17adhesion of symbiont to host cell (GO:0044650)4.17608833
18eye photoreceptor cell differentiation (GO:0001754)4.16897170
19photoreceptor cell differentiation (GO:0046530)4.16897170
20negative regulation of neurotransmitter transport (GO:0051589)4.10325035
21myelination in peripheral nervous system (GO:0022011)4.04521051
22peripheral nervous system axon ensheathment (GO:0032292)4.04521051
23glycerophospholipid catabolic process (GO:0046475)3.98905859
24response to redox state (GO:0051775)3.97461572
25long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.94670229
26import into cell (GO:0098657)3.92942285
27oligodendrocyte differentiation (GO:0048709)3.84731655
28asymmetric protein localization (GO:0008105)3.84489380
29response to lipoprotein particle (GO:0055094)3.81861007
30creatine metabolic process (GO:0006600)3.81328493
31response to methylmercury (GO:0051597)3.80750254
32isoprenoid biosynthetic process (GO:0008299)3.76853225
33negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.76378211
34amino acid import (GO:0043090)3.64677603
35apical protein localization (GO:0045176)3.63241494
36positive regulation of actin filament depolymerization (GO:0030836)3.63124613
37regulation of pigment cell differentiation (GO:0050932)3.58983305
38amyloid precursor protein metabolic process (GO:0042982)3.58009574
39long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.55299671
40substantia nigra development (GO:0021762)3.48517755
41peptidyl-tyrosine autophosphorylation (GO:0038083)3.47233175
42fatty-acyl-CoA biosynthetic process (GO:0046949)3.44299127
43response to hepatocyte growth factor (GO:0035728)3.42605590
44cellular response to hepatocyte growth factor stimulus (GO:0035729)3.42605590
45positive regulation of oligodendrocyte differentiation (GO:0048714)3.39010089
46negative regulation of protein localization to cell surface (GO:2000009)3.38032878
47endothelial cell proliferation (GO:0001935)3.35066131
48astrocyte development (GO:0014002)3.31757902
49Golgi to endosome transport (GO:0006895)3.29234940
50neuron cell-cell adhesion (GO:0007158)3.15777245
51adhesion of symbiont to host (GO:0044406)3.15319013
52fatty-acyl-CoA metabolic process (GO:0035337)3.14170310
53nucleotide transmembrane transport (GO:1901679)3.11737157
54dermatan sulfate biosynthetic process (GO:0030208)3.08974498
55positive regulation of glycoprotein biosynthetic process (GO:0010560)3.06624960
56protein palmitoylation (GO:0018345)3.00022898
57establishment of mitochondrion localization (GO:0051654)2.95359949
58very long-chain fatty acid metabolic process (GO:0000038)2.93577837
59anterior/posterior axis specification, embryo (GO:0008595)2.93548688
60peripheral nervous system development (GO:0007422)2.93304377
61limb bud formation (GO:0060174)2.92660290
62amyloid precursor protein catabolic process (GO:0042987)2.90826981
63nerve growth factor signaling pathway (GO:0038180)2.90821807
64embryonic retina morphogenesis in camera-type eye (GO:0060059)2.90531682
65L-serine transport (GO:0015825)2.89646947
66righting reflex (GO:0060013)2.87456152
67Rap protein signal transduction (GO:0032486)2.87361029
68UDP-N-acetylglucosamine metabolic process (GO:0006047)2.87043997
69presynaptic membrane organization (GO:0097090)2.85869320
70transepithelial transport (GO:0070633)2.84672114
71C4-dicarboxylate transport (GO:0015740)2.81171625
72negative regulation of JUN kinase activity (GO:0043508)2.81087568
73regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.80649177
74ionotropic glutamate receptor signaling pathway (GO:0035235)2.80308115
75genitalia morphogenesis (GO:0035112)2.80171221
76regulation of lipoprotein metabolic process (GO:0050746)2.79492566
77interleukin-6-mediated signaling pathway (GO:0070102)2.78586478
78negative regulation of axonogenesis (GO:0050771)2.78200996
79glycosylceramide metabolic process (GO:0006677)2.77067579
80magnesium ion transport (GO:0015693)2.76756899
81positive regulation of neurological system process (GO:0031646)2.74834790
82cellular response to epinephrine stimulus (GO:0071872)2.72982725
83presynaptic membrane assembly (GO:0097105)2.72579367
84acyl-CoA biosynthetic process (GO:0071616)2.68935320
85thioester biosynthetic process (GO:0035384)2.68935320
86positive regulation of cell cycle checkpoint (GO:1901978)2.68644327
87dermatan sulfate metabolic process (GO:0030205)2.66829184
88prostate gland growth (GO:0060736)2.64081887
89neuron remodeling (GO:0016322)2.63310961
90positive regulation of glycoprotein metabolic process (GO:1903020)2.60522969
91negative regulation of axon extension (GO:0030517)2.60421243
92transmission of nerve impulse (GO:0019226)2.59688276
93vocalization behavior (GO:0071625)2.58728947
94axonal fasciculation (GO:0007413)2.57240818
95glutamate receptor signaling pathway (GO:0007215)2.55036468
96regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.53381355
97neuronal ion channel clustering (GO:0045161)2.53211885
98lipid translocation (GO:0034204)2.53036606
99phospholipid translocation (GO:0045332)2.53036606
100enteric nervous system development (GO:0048484)2.52921572
101membrane protein ectodomain proteolysis (GO:0006509)2.52430330
102activated T cell proliferation (GO:0050798)2.52370792
103positive regulation of developmental pigmentation (GO:0048087)2.51873566
104ceramide biosynthetic process (GO:0046513)2.51472143
105positive regulation of meiosis (GO:0045836)2.50340812
106leukocyte migration involved in inflammatory response (GO:0002523)2.46844367
107exploration behavior (GO:0035640)2.46293456
108calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.44497359
109membrane tubulation (GO:0097320)2.43260552
110regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.41369842
111cell-cell junction assembly (GO:0007043)2.40436334
112positive regulation of glial cell differentiation (GO:0045687)2.39371295
113Leydig cell differentiation (GO:0033327)2.37864880
114cellular response to ethanol (GO:0071361)2.37650184
115axon development (GO:0061564)2.35099342
116cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.34651873
117Golgi to plasma membrane protein transport (GO:0043001)2.33955097
118cholesterol metabolic process (GO:0008203)2.33333746
119positive regulation of synapse assembly (GO:0051965)2.32521121
120positive regulation of gliogenesis (GO:0014015)2.32299810
121protein localization to endosome (GO:0036010)2.31713272
122semaphorin-plexin signaling pathway (GO:0071526)2.30951567
123lysine catabolic process (GO:0006554)2.30903377
124lysine metabolic process (GO:0006553)2.30903377
125positive regulation of meiotic cell cycle (GO:0051446)2.30701030
126cyclic nucleotide catabolic process (GO:0009214)2.29515481
127gap junction assembly (GO:0016264)2.29403041
128cellular response to catecholamine stimulus (GO:0071870)2.29024657
129cellular response to monoamine stimulus (GO:0071868)2.29024657
130synaptic vesicle docking involved in exocytosis (GO:0016081)2.28058613
131peptidyl-cysteine modification (GO:0018198)2.27652198
132response to epinephrine (GO:0071871)2.26950876
133regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.26239927
134regulation of short-term neuronal synaptic plasticity (GO:0048172)2.25958466
135cellular glucuronidation (GO:0052695)2.25519783
136postsynaptic membrane organization (GO:0001941)2.25229364
137nucleotide transport (GO:0006862)2.24156338
138neural nucleus development (GO:0048857)2.23818564
139cellular potassium ion homeostasis (GO:0030007)2.23563769
140glomerular visceral epithelial cell development (GO:0072015)2.22975960
141neuron recognition (GO:0008038)2.22892392
142cranial nerve development (GO:0021545)2.22708679
143cerebral cortex radially oriented cell migration (GO:0021799)2.22678334
144myelin assembly (GO:0032288)2.22095572
145sulfation (GO:0051923)2.21912569
146acidic amino acid transport (GO:0015800)2.21353974
147receptor recycling (GO:0001881)2.21086203
148dorsal/ventral axis specification (GO:0009950)2.20485517
149adult walking behavior (GO:0007628)2.19963051
150ectoderm development (GO:0007398)2.19797915
151glial cell development (GO:0021782)2.19526306
152prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.18856628
153positive regulation of pseudopodium assembly (GO:0031274)2.18354946
154membrane assembly (GO:0071709)2.18272815
155cGMP-mediated signaling (GO:0019934)2.18110263
156cellular response to cholesterol (GO:0071397)2.17378262
157regulation of phospholipid biosynthetic process (GO:0071071)2.17259405
158sphingolipid biosynthetic process (GO:0030148)2.17007564
159intestinal absorption (GO:0050892)2.16151160
160serine transport (GO:0032329)2.16087365
161synaptic transmission, glutamatergic (GO:0035249)2.15534451
162regulation of axon extension involved in axon guidance (GO:0048841)2.13815536
163regulation of protein glycosylation (GO:0060049)2.13504620
164zinc ion transport (GO:0006829)2.13379488
165regulation of myelination (GO:0031641)2.13230386
166positive regulation of dendritic spine morphogenesis (GO:0061003)2.12892433
167regulation of non-canonical Wnt signaling pathway (GO:2000050)2.12674138
168glucuronate metabolic process (GO:0019585)2.11242638
169uronic acid metabolic process (GO:0006063)2.11242638
170positive regulation of amino acid transport (GO:0051957)2.09933460

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.62484450
2GBX2_23144817_ChIP-Seq_PC3_Human2.45049605
3ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.34622752
4SALL1_21062744_ChIP-ChIP_HESCs_Human2.33111740
5CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.20525798
6* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.09139679
7* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.97254347
8NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.93761783
9NRF2_20460467_ChIP-Seq_MEFs_Mouse1.93761783
10AR_21572438_ChIP-Seq_LNCaP_Human1.89243486
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.89150942
12* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.88683808
13VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.88349218
14TRIM28_21343339_ChIP-Seq_HEK293_Human1.87603902
15SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.73983031
16WT1_19549856_ChIP-ChIP_CCG9911_Human1.67993147
17PIAS1_25552417_ChIP-Seq_VCAP_Human1.65128259
18* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.63582865
19CDX2_20551321_ChIP-Seq_CACO-2_Human1.58874438
20* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.58191490
21MTF2_20144788_ChIP-Seq_MESCs_Mouse1.57326841
22FLI1_27457419_Chip-Seq_LIVER_Mouse1.55532452
23TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.53642477
24SMAD_19615063_ChIP-ChIP_OVARY_Human1.53510366
25* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.52019754
26CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51813688
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51763747
28ER_23166858_ChIP-Seq_MCF-7_Human1.50977739
29SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.49643912
30SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.49333701
31EZH2_18974828_ChIP-Seq_MESCs_Mouse1.48401024
32RNF2_18974828_ChIP-Seq_MESCs_Mouse1.48401024
33SMAD3_21741376_ChIP-Seq_HESCs_Human1.47869230
34SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.47806386
35EWS_26573619_Chip-Seq_HEK293_Human1.47737328
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.47185503
37EP300_21415370_ChIP-Seq_HL-1_Mouse1.47003819
38* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.45230349
39SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.44714661
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44202446
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.43947943
42SMAD3_21741376_ChIP-Seq_EPCs_Human1.43489557
43JARID2_20064375_ChIP-Seq_MESCs_Mouse1.42196103
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.41988721
45BCAT_22108803_ChIP-Seq_LS180_Human1.41334003
46TAF15_26573619_Chip-Seq_HEK293_Human1.40389294
47ESR1_21235772_ChIP-Seq_MCF-7_Human1.39788210
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.38846559
49ESR2_21235772_ChIP-Seq_MCF-7_Human1.38173932
50TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37200798
51VDR_22108803_ChIP-Seq_LS180_Human1.36879761
52AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36586428
53EZH2_27294783_Chip-Seq_NPCs_Mouse1.35234875
54PCGF2_27294783_Chip-Seq_ESCs_Mouse1.34639892
55* P53_22387025_ChIP-Seq_ESCs_Mouse1.34159997
56EZH2_27304074_Chip-Seq_ESCs_Mouse1.33524088
57AR_21909140_ChIP-Seq_LNCAP_Human1.33368226
58DROSHA_22980978_ChIP-Seq_HELA_Human1.33339476
59ESR1_20079471_ChIP-ChIP_T-47D_Human1.31033019
60SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.30855339
61AR_25329375_ChIP-Seq_VCAP_Human1.29227364
62RNF2_27304074_Chip-Seq_ESCs_Mouse1.29201744
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29083560
64E2F1_18555785_Chip-Seq_ESCs_Mouse1.29077651
65TCF4_22108803_ChIP-Seq_LS180_Human1.28753659
66SUZ12_27294783_Chip-Seq_NPCs_Mouse1.28656447
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27794576
68YAP1_20516196_ChIP-Seq_MESCs_Mouse1.27732288
69PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27266213
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.26679848
71SOX2_21211035_ChIP-Seq_LN229_Gbm1.25621425
72* AHR_22903824_ChIP-Seq_MCF-7_Human1.23351433
73JARID2_20075857_ChIP-Seq_MESCs_Mouse1.22600570
74SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22001370
75TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.21283222
76* SOX2_20726797_ChIP-Seq_SW620_Human1.20595158
77P300_19829295_ChIP-Seq_ESCs_Human1.20202394
78RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.18894218
79CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.18749706
80* SMAD4_21741376_ChIP-Seq_HESCs_Human1.18718458
81CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.17432117
82PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.15796901
83FOXO3_23340844_ChIP-Seq_DLD1_Human1.14866402
84RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14180745
85OCT4_18555785_Chip-Seq_ESCs_Mouse1.14079824
86STAT3_23295773_ChIP-Seq_U87_Human1.13406229
87MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.12938042
88FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.12561999
89IGF1R_20145208_ChIP-Seq_DFB_Human1.12512440
90TBX3_20139965_ChIP-Seq_MESCs_Mouse1.12326204
91TBX3_20139965_ChIP-Seq_ESCs_Mouse1.12126836
92CDX2_22108803_ChIP-Seq_LS180_Human1.11317463
93KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.11066942
94KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.11066942
95KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.11066942
96CJUN_26792858_Chip-Seq_BT549_Human1.10927258
97FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.10266349
98* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10190743
99STAT3_18555785_Chip-Seq_ESCs_Mouse1.10022764
100* ARNT_22903824_ChIP-Seq_MCF-7_Human1.09533822
101TP53_16413492_ChIP-PET_HCT116_Human1.08720038
102CTBP1_25329375_ChIP-Seq_LNCAP_Human1.08297325
103TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.07821754
104EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07010368
105SOX2_18555785_Chip-Seq_ESCs_Mouse1.06786306
106* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.06566185
107NFE2_27457419_Chip-Seq_LIVER_Mouse1.06534639
108TCF4_18268006_ChIP-ChIP_LS174T_Human1.06269870
109NMYC_18555785_Chip-Seq_ESCs_Mouse1.05588809
110CMYC_18555785_Chip-Seq_ESCs_Mouse1.05385682
111FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.05241137
112* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.04827156
113RUNX2_22187159_ChIP-Seq_PCA_Human1.04492766
114* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.04349521
115PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.04221650
116ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03951249
117CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03950850
118TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03041754
119SMAD4_21799915_ChIP-Seq_A2780_Human1.02932323
120FUS_26573619_Chip-Seq_HEK293_Human1.02373223
121CTBP2_25329375_ChIP-Seq_LNCAP_Human1.02067782
122LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02016028
123TP53_18474530_ChIP-ChIP_U2OS_Human1.01944417
124NANOG_18555785_Chip-Seq_ESCs_Mouse1.00868410
125TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00264069
126SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98987718
127CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.98985082
128E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.98943928
129CTNNB1_20460455_ChIP-Seq_HCT116_Human0.98091322
130NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98021075
131* TP63_23658742_ChIP-Seq_EP156T_Human0.95950651
132GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95849850
133NR3C1_23031785_ChIP-Seq_PC12_Mouse0.94702283
134PPAR_26484153_Chip-Seq_NCI-H1993_Human0.93976955
135SUZ12_18555785_Chip-Seq_ESCs_Mouse0.93862321
136* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.93735821
137EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.93597362
138SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.93384549
139BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.93348372
140* FOXA2_19822575_ChIP-Seq_HepG2_Human0.92832893
141P300_18555785_Chip-Seq_ESCs_Mouse0.92799090
142EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.92738841
143RXR_22108803_ChIP-Seq_LS180_Human0.91604200
144CBX2_27304074_Chip-Seq_ESCs_Mouse0.91321966
145* TCF4_23295773_ChIP-Seq_U87_Human0.90886625

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination5.57347736
2MP0003690_abnormal_glial_cell3.77369543
3MP0003950_abnormal_plasma_membrane3.45853662
4MP0005171_absent_coat_pigmentation3.32431096
5MP0002736_abnormal_nociception_after2.91774602
6MP0010234_abnormal_vibrissa_follicle2.81793802
7MP0004885_abnormal_endolymph2.71268623
8MP0008438_abnormal_cutaneous_collagen2.67113129
9MP0006054_spinal_hemorrhage2.66872033
10MP0010678_abnormal_skin_adnexa2.60287207
11MP0004742_abnormal_vestibular_system2.57669776
12MP0004270_analgesia2.53895044
13MP0001968_abnormal_touch/_nociception2.43252858
14MP0003634_abnormal_glial_cell2.40155976
15MP0000462_abnormal_digestive_system2.34081582
16MP0003329_amyloid_beta_deposits2.30715010
17MP0005360_urolithiasis2.27874945
18MP0000383_abnormal_hair_follicle2.27526748
19MP0003136_yellow_coat_color2.22790372
20MP0003880_abnormal_central_pattern2.20830617
21MP0004134_abnormal_chest_morphology2.14538969
22MP0001485_abnormal_pinna_reflex2.12971770
23MP0003890_abnormal_embryonic-extraembry2.07746184
24MP0002735_abnormal_chemical_nociception2.02416519
25MP0003195_calcinosis1.97666149
26MP0000778_abnormal_nervous_system1.95126324
27MP0003632_abnormal_nervous_system1.93259836
28MP0003941_abnormal_skin_development1.88031682
29MP0001984_abnormal_olfaction1.86608215
30MP0003868_abnormal_feces_composition1.85510882
31MP0001346_abnormal_lacrimal_gland1.82106104
32MP0002272_abnormal_nervous_system1.81372364
33MP0001299_abnormal_eye_distance/1.81232932
34MP0002282_abnormal_trachea_morphology1.67799720
35MP0001486_abnormal_startle_reflex1.67105789
36MP0004272_abnormal_basement_membrane1.66274726
37MP0001905_abnormal_dopamine_level1.66219187
38MP0010352_gastrointestinal_tract_polyps1.65681417
39MP0000604_amyloidosis1.65173583
40MP0000647_abnormal_sebaceous_gland1.56845252
41MP0001661_extended_life_span1.55409014
42MP0001986_abnormal_taste_sensitivity1.54607132
43MP0005408_hypopigmentation1.53762481
44MP0002295_abnormal_pulmonary_circulatio1.53050082
45MP0005623_abnormal_meninges_morphology1.52226766
46MP0001529_abnormal_vocalization1.50430167
47MP0002229_neurodegeneration1.49131021
48MP0005409_darkened_coat_color1.47291231
49MP0001177_atelectasis1.47182447
50MP0004043_abnormal_pH_regulation1.44415265
51MP0003806_abnormal_nucleotide_metabolis1.44074967
52MP0000566_synostosis1.42764826
53MP0000762_abnormal_tongue_morphology1.39416651
54MP0005551_abnormal_eye_electrophysiolog1.31229433
55MP0002064_seizures1.28432132
56MP0002734_abnormal_mechanical_nocicepti1.25171311
57MP0004381_abnormal_hair_follicle1.24243639
58MP0003631_nervous_system_phenotype1.24168223
59MP0004142_abnormal_muscle_tone1.22498353
60MP0004185_abnormal_adipocyte_glucose1.20546351
61MP0000579_abnormal_nail_morphology1.18763844
62MP0005058_abnormal_lysosome_morphology1.18019121
63MP0005365_abnormal_bile_salt1.15603216
64MP0005451_abnormal_body_composition1.14985882
65MP0003453_abnormal_keratinocyte_physiol1.11178233
66MP0004264_abnormal_extraembryonic_tissu1.10525035
67MP0003937_abnormal_limbs/digits/tail_de1.09973647
68MP0002063_abnormal_learning/memory/cond1.06637497
69MP0000467_abnormal_esophagus_morphology1.04469993
70MP0001501_abnormal_sleep_pattern1.04427592
71MP0005275_abnormal_skin_tensile1.03640041
72MP0002882_abnormal_neuron_morphology1.03447268
73MP0000516_abnormal_urinary_system1.03277862
74MP0005367_renal/urinary_system_phenotyp1.03277862
75MP0002572_abnormal_emotion/affect_behav1.02901653
76MP0000955_abnormal_spinal_cord1.01884960
77MP0005388_respiratory_system_phenotype1.01345003
78MP0002133_abnormal_respiratory_system1.01345003
79MP0003633_abnormal_nervous_system1.01316251
80MP0005195_abnormal_posterior_eye1.00604984
81MP0002090_abnormal_vision0.99369018
82MP0001963_abnormal_hearing_physiology0.97974323
83MP0005310_abnormal_salivary_gland0.97304979
84MP0001851_eye_inflammation0.96949620
85MP0005503_abnormal_tendon_morphology0.96609442
86MP0003115_abnormal_respiratory_system0.95390576
87MP0002249_abnormal_larynx_morphology0.93254135
88MP0005410_abnormal_fertilization0.92928269
89MP0010368_abnormal_lymphatic_system0.91885694
90MP0005085_abnormal_gallbladder_physiolo0.90232226
91MP0000537_abnormal_urethra_morphology0.88671042
92MP0009250_abnormal_appendicular_skeleto0.87361441
93MP0009384_cardiac_valve_regurgitation0.85489552
94MP0002752_abnormal_somatic_nervous0.85365883
95MP0005083_abnormal_biliary_tract0.85086736
96MP0000427_abnormal_hair_cycle0.84462429
97MP0004924_abnormal_behavior0.83955239
98MP0005386_behavior/neurological_phenoty0.83955239
99MP0003119_abnormal_digestive_system0.83427306
100MP0005253_abnormal_eye_physiology0.83358502
101MP0002009_preneoplasia0.82839725
102MP0008004_abnormal_stomach_pH0.82678536
103MP0004145_abnormal_muscle_electrophysio0.82335194
104MP0003935_abnormal_craniofacial_develop0.81707229
105MP0002108_abnormal_muscle_morphology0.81539214
106MP0008057_abnormal_DNA_replication0.80918000
107MP0002067_abnormal_sensory_capabilities0.80737951
108MP0009780_abnormal_chondrocyte_physiolo0.79611712
109MP0008872_abnormal_physiological_respon0.77763778
110MP0002098_abnormal_vibrissa_morphology0.77299102
111MP0010329_abnormal_lipoprotein_level0.77186677
112MP0002557_abnormal_social/conspecific_i0.77069729
113MP0005508_abnormal_skeleton_morphology0.76583160
114MP0002066_abnormal_motor_capabilities/c0.75486195
115MP0006082_CNS_inflammation0.74876701
116MP0009745_abnormal_behavioral_response0.74763961
117MP0008569_lethality_at_weaning0.74504724
118MP0000747_muscle_weakness0.74208031
119MP0000613_abnormal_salivary_gland0.73959901
120MP0001440_abnormal_grooming_behavior0.73796683
121MP0003172_abnormal_lysosome_physiology0.73649847
122MP0002254_reproductive_system_inflammat0.73506874
123MP0009046_muscle_twitch0.71081573
124MP0010771_integument_phenotype0.70935945
125MP0003385_abnormal_body_wall0.69553807
126MP0000428_abnormal_craniofacial_morphol0.67719853
127MP0003183_abnormal_peptide_metabolism0.67458804
128MP0003283_abnormal_digestive_organ0.67364317
129MP0001970_abnormal_pain_threshold0.67057736
130MP0000003_abnormal_adipose_tissue0.67017138
131MP0002115_abnormal_skeleton_extremities0.66964189
132MP0003938_abnormal_ear_development0.66446982
133MP0002168_other_aberrant_phenotype0.66015764
134MP0005423_abnormal_somatic_nervous0.65812624
135MP0002796_impaired_skin_barrier0.64405319
136MP0000377_abnormal_hair_follicle0.63232199
137MP0001666_abnormal_nutrient_absorption0.62399539
138MP0001340_abnormal_eyelid_morphology0.61835570
139MP0003635_abnormal_synaptic_transmissio0.61112087
140MP0004858_abnormal_nervous_system0.60604017
141MP0008260_abnormal_autophagy0.60086367
142MP0004859_abnormal_synaptic_plasticity0.57569126

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)6.68026043
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.68026043
3Neurofibrillary tangles (HP:0002185)5.70162504
4Abnormality of the corticospinal tract (HP:0002492)4.93060157
5Parakeratosis (HP:0001036)4.66796456
6Sensory axonal neuropathy (HP:0003390)4.53059497
7Vitreoretinal degeneration (HP:0000655)4.37405175
8Peripheral hypomyelination (HP:0007182)4.29522181
9Onion bulb formation (HP:0003383)3.99611985
10Cerebral inclusion bodies (HP:0100314)3.93852374
11Insidious onset (HP:0003587)3.87590665
12Termporal pattern (HP:0011008)3.87590665
13Abnormality of the lumbar spine (HP:0100712)3.75343073
14Alacrima (HP:0000522)3.58427710
15Abnormal auditory evoked potentials (HP:0006958)3.57626531
16Focal motor seizures (HP:0011153)3.51020572
17Missing ribs (HP:0000921)3.34285017
18Segmental peripheral demyelination/remyelination (HP:0003481)3.29347778
19Disproportionate short-trunk short stature (HP:0003521)3.24362752
20Intention tremor (HP:0002080)3.24211382
21Myelomeningocele (HP:0002475)3.16554252
22Tracheomalacia (HP:0002779)3.16110892
23Enlarged kidneys (HP:0000105)3.15313557
24Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.12725805
25Embryonal renal neoplasm (HP:0011794)3.10208102
26Premature skin wrinkling (HP:0100678)3.09951883
27Spastic diplegia (HP:0001264)3.03175650
28Supranuclear gaze palsy (HP:0000605)3.02411365
29Pili torti (HP:0003777)3.00645873
30Focal seizures (HP:0007359)2.98269557
31Spastic gait (HP:0002064)2.95745243
32Abnormal vertebral ossification (HP:0100569)2.94584355
33Protuberant abdomen (HP:0001538)2.93169406
34Cerebral hypomyelination (HP:0006808)2.90310487
35Chorioretinal atrophy (HP:0000533)2.82522973
36Aplasia involving bones of the extremities (HP:0009825)2.77118831
37Aplasia involving bones of the upper limbs (HP:0009823)2.77118831
38Aplasia of the phalanges of the hand (HP:0009802)2.77118831
39Decreased lacrimation (HP:0000633)2.73075908
40Congenital ichthyosiform erythroderma (HP:0007431)2.72166354
41Increased corneal curvature (HP:0100692)2.70215590
42Keratoconus (HP:0000563)2.70215590
43Akinesia (HP:0002304)2.67469187
44Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.62771005
45Stridor (HP:0010307)2.62456482
46Anteriorly placed anus (HP:0001545)2.59983610
47Slow saccadic eye movements (HP:0000514)2.59215754
48Papillary thyroid carcinoma (HP:0002895)2.55768423
49Adrenal hypoplasia (HP:0000835)2.55536365
50Hyperventilation (HP:0002883)2.49446222
51Absent speech (HP:0001344)2.49331347
52Visceral angiomatosis (HP:0100761)2.48953461
53Dysmetria (HP:0001310)2.48211463
54Thick nail (HP:0001805)2.43097855
55Increased circulating renin level (HP:0000848)2.42436775
56Coronal craniosynostosis (HP:0004440)2.42263975
57Scanning speech (HP:0002168)2.41745977
58Tetraparesis (HP:0002273)2.40357049
59Hypoplasia of the iris (HP:0007676)2.40312263
60Cerebral hemorrhage (HP:0001342)2.39315451
61Small epiphyses (HP:0010585)2.37970285
62Esophageal atresia (HP:0002032)2.35753337
63Hemangiomatosis (HP:0007461)2.34342652
64Abdominal distention (HP:0003270)2.32908434
65Abnormality of the phalanges of the 2nd finger (HP:0009541)2.32263030
66White forelock (HP:0002211)2.30770021
67Morphological abnormality of the inner ear (HP:0011390)2.30076521
68Axonal loss (HP:0003447)2.29776616
69Ileus (HP:0002595)2.28484418
70Action tremor (HP:0002345)2.28434682
71Neoplasm of the oral cavity (HP:0100649)2.28393968
72Hypoplastic pelvis (HP:0008839)2.26299129
73Retinal dysplasia (HP:0007973)2.25051943
74Spastic paraparesis (HP:0002313)2.24514800
75Abnormality of aspartate family amino acid metabolism (HP:0010899)2.24095598
76Submucous cleft hard palate (HP:0000176)2.23399896
77Epiphyseal dysplasia (HP:0002656)2.22736125
78Patchy hypopigmentation of hair (HP:0011365)2.22723809
79Cupped ear (HP:0000378)2.22127872
80Autoamputation (HP:0001218)2.21590615
81Clumsiness (HP:0002312)2.17610960
82Peripheral demyelination (HP:0011096)2.17192864
83Ankle clonus (HP:0011448)2.14560721
84Metabolic alkalosis (HP:0200114)2.12781947
85Neoplasm of the small intestine (HP:0100833)2.11193787
86Leukodystrophy (HP:0002415)2.08658040
87Infantile muscular hypotonia (HP:0008947)2.08603257
88Thickened helices (HP:0000391)2.07848132
89Hepatosplenomegaly (HP:0001433)2.05953507
90Abnormality of incisor morphology (HP:0011063)2.04746115
91Decreased motor nerve conduction velocity (HP:0003431)2.04535865
92Lower limb muscle weakness (HP:0007340)2.02346689
93Right ventricular cardiomyopathy (HP:0011663)2.02159424
94Bifid scrotum (HP:0000048)2.00943227
95Hypophosphatemic rickets (HP:0004912)1.98320417
96Abnormality of glycolysis (HP:0004366)1.98043589
97Increased serum pyruvate (HP:0003542)1.98043589
98Abnormality of the middle phalanges of the toes (HP:0010183)1.97074921
99Abnormal hair laboratory examination (HP:0003328)1.96929821
100Abnormal hair whorl (HP:0010721)1.94340921
101Synostosis involving the elbow (HP:0003938)1.94202581
102Humeroradial synostosis (HP:0003041)1.94202581
103Hypomagnesemia (HP:0002917)1.94127687
104Mixed hearing impairment (HP:0000410)1.93660198
105Large earlobe (HP:0009748)1.93465858
106Premature rupture of membranes (HP:0001788)1.93149220
107Pheochromocytoma (HP:0002666)1.93021048
108Relative macrocephaly (HP:0004482)1.91712346
109Abolished electroretinogram (ERG) (HP:0000550)1.90934708
110Foot dorsiflexor weakness (HP:0009027)1.90803279
111Drooling (HP:0002307)1.90360699
112Split foot (HP:0001839)1.90133775
113Hypokalemic alkalosis (HP:0001949)1.88893018
114Absent septum pellucidum (HP:0001331)1.85676579
115Protruding tongue (HP:0010808)1.85293816
116Hammertoe (HP:0001765)1.84816592
117Hyporeflexia of lower limbs (HP:0002600)1.84775311
118Hypoglycemic seizures (HP:0002173)1.84278846
119Hyperactive renin-angiotensin system (HP:0000841)1.83721201
120Intrahepatic cholestasis (HP:0001406)1.81957660
121Stenosis of the external auditory canal (HP:0000402)1.81702332
122Broad metatarsal (HP:0001783)1.81556128
123Barrel-shaped chest (HP:0001552)1.79271142
124Preaxial foot polydactyly (HP:0001841)1.78988393
125Steppage gait (HP:0003376)1.78277645
126Hypopigmentation of the fundus (HP:0007894)1.77726845
127Bell-shaped thorax (HP:0001591)1.76898448
128Paraparesis (HP:0002385)1.76118242
129Pendular nystagmus (HP:0012043)1.75931854
130Ulnar claw (HP:0001178)1.74758608
131Hypoplastic labia majora (HP:0000059)1.74199217
132Widely spaced teeth (HP:0000687)1.73904815
133Distal sensory impairment (HP:0002936)1.73343748
134Hyperaldosteronism (HP:0000859)1.73338897
135Volvulus (HP:0002580)1.73067531
136Gaze-evoked nystagmus (HP:0000640)1.72991037
137Congenital sensorineural hearing impairment (HP:0008527)1.72503431
138Conical tooth (HP:0000698)1.72342892
139Megalencephaly (HP:0001355)1.71191723
140Abnormality of the vitreous humor (HP:0004327)1.70999050
141Clonus (HP:0002169)1.69640803
142Gowers sign (HP:0003391)1.68768919
143Stomach cancer (HP:0012126)1.68281412
144Scapular winging (HP:0003691)1.68118269
145Hemiparesis (HP:0001269)1.67476160
146Delayed epiphyseal ossification (HP:0002663)1.66586114
147Broad-based gait (HP:0002136)1.66403128
148Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.65160330
149Spastic paraplegia (HP:0001258)1.64667061
150Long nose (HP:0003189)1.64654848
151Abnormal biliary tract morphology (HP:0012440)1.64420690
152Thyroid carcinoma (HP:0002890)1.62258678
153Excessive salivation (HP:0003781)1.61252453
154Abnormality of the axillary hair (HP:0100134)1.61185578
155Abnormality of secondary sexual hair (HP:0009888)1.61185578
156Blue irides (HP:0000635)1.60958436
157Curly hair (HP:0002212)1.60789332
158Bilateral sensorineural hearing impairment (HP:0008619)1.59328154
159Intellectual disability, moderate (HP:0002342)1.58607479
160Biliary tract neoplasm (HP:0100574)1.57997710
161Abnormality of the ischium (HP:0003174)1.57409576
162Fair hair (HP:0002286)1.56789845
163Short hallux (HP:0010109)1.54513278
164Lymphangioma (HP:0100764)1.54372562
165Morphological abnormality of the pyramidal tract (HP:0002062)1.54080539
166Dysdiadochokinesis (HP:0002075)1.54037128
167Bifid tongue (HP:0010297)1.53673113
168Abnormality of renin-angiotensin system (HP:0000847)1.52877335
169Gonadotropin excess (HP:0000837)1.52372627

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK396.18417458
2EPHB14.14130457
3OXSR13.96683303
4ACVR1B3.76294847
5BCR2.95033659
6PBK2.95022776
7MET2.67793054
8PKN12.59947952
9FGFR22.40816691
10TNIK2.40614427
11WNK42.31453120
12TAF12.22792033
13TYRO32.02555500
14WNK12.02488991
15YES11.91368677
16MST41.90645457
17MAPKAPK51.81791047
18NEK61.77186021
19LIMK11.74255032
20NTRK11.67097210
21ICK1.62798490
22PLK21.58717838
23IRAK21.51336511
24PRPF4B1.49969235
25SCYL21.46079870
26WNK31.42877508
27SGK2231.42239382
28SGK4941.42239382
29CSNK1A1L1.40403006
30UHMK11.39735867
31ROCK21.37566278
32ERBB31.36524202
33PLK41.33734890
34AKT31.32722300
35MAP3K21.31438906
36PDGFRA1.30704701
37BRD41.30663668
38STK38L1.26648609
39MAP3K41.24699574
40FGR1.22331183
41IRAK11.19958854
42MKNK21.18993419
43CSNK1G31.18561509
44CAMK2B1.17716973
45TRIM281.15588010
46CAMK2D1.13297447
47FGFR11.11776322
48MINK11.09951163
49MARK11.08648312
50LATS21.08445599
51TGFBR11.07420846
52TIE10.99924454
53CSNK1G10.97889789
54SGK20.94432404
55PDGFRB0.93570573
56CLK10.90699034
57CSNK1G20.88440154
58DDR20.87879205
59EIF2AK30.87268233
60MKNK10.85918082
61BMPR1B0.85844464
62ERBB40.83727535
63PAK30.83688439
64PRKCQ0.83609362
65STK30.82968754
66PIK3CA0.82273679
67CAMK2G0.80720961
68PRKCE0.79640360
69CASK0.79165515
70EPHA40.79128594
71NTRK30.77325020
72PAK60.77069073
73NTRK20.76639135
74GSK3A0.75210254
75FES0.73596258
76STK240.72227875
77PRKCG0.70999481
78LATS10.70787198
79TSSK60.70733078
80TESK20.69925358
81FLT30.69394180
82MAPK150.68940827
83SGK30.68362691
84BMPR20.68274435
85MAP3K130.67849846
86WEE10.67565198
87MAP2K10.67283130
88PRKD10.66515523
89PTK20.66194628
90MAP3K140.65493493
91CDK190.64705176
92MAP2K20.64538727
93CAMK2A0.64354008
94BMX0.64281146
95IRAK40.64280339
96PDPK10.63735391
97DYRK20.63553314
98MAPK130.63548069
99MAP4K20.63027627
100MAP3K90.63026916
101KSR20.62757379
102PNCK0.62279367
103CAMK1G0.61120756
104INSRR0.60153796
105CSK0.59634119
106NUAK10.58119567
107ROCK10.57906426
108PLK30.57183758
109CDK50.53808326
110TRPM70.52959031
111INSR0.52590844
112MST1R0.52085075
113FYN0.51194690
114EPHA30.50641052
115PRKCH0.48384178
116FRK0.48285624
117MAPK100.47989732
118CDK140.47463153
119EIF2AK20.45917272
120EPHA20.44478980
121PDK20.44312910
122RIPK10.44104989
123DAPK20.43997159
124LMTK20.43699919
125MARK20.41708774
126CSNK1A10.41091732
127GRK10.40713590
128MELK0.40427080
129CSNK1D0.39888922
130NEK90.38844236
131RPS6KA30.38640305
132FER0.38280842
133RPS6KB10.37406066
134PRKD30.36770688
135PRKG10.36143551
136DMPK0.36017267
137RPS6KA50.34859170
138PHKG20.33889045
139PHKG10.33889045
140SRC0.30257855
141NLK0.30171841
142ARAF0.29896276
143SGK10.29391767
144ERBB20.29022430
145PTK2B0.28117293
146RET0.27534115

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009005.33625710
2Steroid biosynthesis_Homo sapiens_hsa001005.14584581
3Fatty acid elongation_Homo sapiens_hsa000623.81157445
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.05442984
5Ether lipid metabolism_Homo sapiens_hsa005652.96215644
6Sulfur metabolism_Homo sapiens_hsa009202.84380891
7Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.35238193
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.33041375
9Sphingolipid metabolism_Homo sapiens_hsa006001.85971486
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.83061042
11Axon guidance_Homo sapiens_hsa043601.72221759
12Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.71501128
13Nicotine addiction_Homo sapiens_hsa050331.62520230
14Pentose and glucuronate interconversions_Homo sapiens_hsa000401.55517108
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.54654423
16Protein export_Homo sapiens_hsa030601.54135974
17Histidine metabolism_Homo sapiens_hsa003401.53020351
18Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.51904912
19Long-term potentiation_Homo sapiens_hsa047201.44256154
20Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.43887463
21Nitrogen metabolism_Homo sapiens_hsa009101.42479184
22beta-Alanine metabolism_Homo sapiens_hsa004101.38517790
23Circadian entrainment_Homo sapiens_hsa047131.37345229
24Renin secretion_Homo sapiens_hsa049241.28946538
25Linoleic acid metabolism_Homo sapiens_hsa005911.27846787
26Caffeine metabolism_Homo sapiens_hsa002321.25466672
27Tight junction_Homo sapiens_hsa045301.24692979
28Butanoate metabolism_Homo sapiens_hsa006501.23721920
29alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.22413388
30Arginine biosynthesis_Homo sapiens_hsa002201.21906519
31Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.17203740
32Amphetamine addiction_Homo sapiens_hsa050311.16074881
33Non-homologous end-joining_Homo sapiens_hsa034501.14682284
34ECM-receptor interaction_Homo sapiens_hsa045121.10029425
35Renal cell carcinoma_Homo sapiens_hsa052111.09980331
36Vitamin B6 metabolism_Homo sapiens_hsa007501.07933761
37Mineral absorption_Homo sapiens_hsa049781.07464240
38PPAR signaling pathway_Homo sapiens_hsa033201.03934136
39Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.03732314
40Vibrio cholerae infection_Homo sapiens_hsa051101.03079289
41Fatty acid degradation_Homo sapiens_hsa000711.01767054
42Tryptophan metabolism_Homo sapiens_hsa003801.01523401
43Adherens junction_Homo sapiens_hsa045201.00609159
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.99100130
45Cyanoamino acid metabolism_Homo sapiens_hsa004600.98522183
46Thyroid hormone synthesis_Homo sapiens_hsa049180.96806005
47SNARE interactions in vesicular transport_Homo sapiens_hsa041300.95095794
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95030918
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93754575
50Sphingolipid signaling pathway_Homo sapiens_hsa040710.92191625
51Fatty acid metabolism_Homo sapiens_hsa012120.92065120
52Serotonergic synapse_Homo sapiens_hsa047260.89783341
53Lysosome_Homo sapiens_hsa041420.89487948
54ABC transporters_Homo sapiens_hsa020100.89295261
55Arginine and proline metabolism_Homo sapiens_hsa003300.89005030
56Phototransduction_Homo sapiens_hsa047440.88768824
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.88674902
58Glutamatergic synapse_Homo sapiens_hsa047240.88104372
59Rheumatoid arthritis_Homo sapiens_hsa053230.86669325
60Steroid hormone biosynthesis_Homo sapiens_hsa001400.85100915
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84356332
62Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.81812741
63Insulin secretion_Homo sapiens_hsa049110.79804367
64Collecting duct acid secretion_Homo sapiens_hsa049660.78522335
65Renin-angiotensin system_Homo sapiens_hsa046140.76146855
66Dorso-ventral axis formation_Homo sapiens_hsa043200.75945317
67Glycerolipid metabolism_Homo sapiens_hsa005610.75727255
68TGF-beta signaling pathway_Homo sapiens_hsa043500.74798106
69Long-term depression_Homo sapiens_hsa047300.74696324
70Starch and sucrose metabolism_Homo sapiens_hsa005000.73359854
71Phagosome_Homo sapiens_hsa041450.72862880
72Complement and coagulation cascades_Homo sapiens_hsa046100.72174426
73Lysine degradation_Homo sapiens_hsa003100.71185180
74Prion diseases_Homo sapiens_hsa050200.69654602
75Glutathione metabolism_Homo sapiens_hsa004800.69577513
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68106869
77GABAergic synapse_Homo sapiens_hsa047270.67943012
78Peroxisome_Homo sapiens_hsa041460.67583460
79Ovarian steroidogenesis_Homo sapiens_hsa049130.67359310
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.66221815
81Oxidative phosphorylation_Homo sapiens_hsa001900.65973306
82Arachidonic acid metabolism_Homo sapiens_hsa005900.65631920
83Cholinergic synapse_Homo sapiens_hsa047250.65309663
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.64500357
85Ras signaling pathway_Homo sapiens_hsa040140.63597171
86Fatty acid biosynthesis_Homo sapiens_hsa000610.63563312
87Calcium signaling pathway_Homo sapiens_hsa040200.62970553
88Endocytosis_Homo sapiens_hsa041440.62918277
89Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62005005
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.60861598
91Estrogen signaling pathway_Homo sapiens_hsa049150.60468972
92cGMP-PKG signaling pathway_Homo sapiens_hsa040220.59547626
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.59026993
94Protein digestion and absorption_Homo sapiens_hsa049740.57593960
95Malaria_Homo sapiens_hsa051440.56264347
96Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56220582
97Pancreatic secretion_Homo sapiens_hsa049720.56127984
98Wnt signaling pathway_Homo sapiens_hsa043100.55083683
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.54939580
100Synaptic vesicle cycle_Homo sapiens_hsa047210.54773906
101Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.54623890
102Rap1 signaling pathway_Homo sapiens_hsa040150.54259394
103Propanoate metabolism_Homo sapiens_hsa006400.53080172
104Inositol phosphate metabolism_Homo sapiens_hsa005620.52993922
105cAMP signaling pathway_Homo sapiens_hsa040240.52879433
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52424172
107Chemical carcinogenesis_Homo sapiens_hsa052040.52265439
108* Choline metabolism in cancer_Homo sapiens_hsa052310.51991047
109Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50977148
110Focal adhesion_Homo sapiens_hsa045100.48475801
111Prostate cancer_Homo sapiens_hsa052150.47653544
112Alzheimers disease_Homo sapiens_hsa050100.47163740
113Vitamin digestion and absorption_Homo sapiens_hsa049770.46843143
114Taste transduction_Homo sapiens_hsa047420.46485500
115Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.45655330
116Glycerophospholipid metabolism_Homo sapiens_hsa005640.45575286
117Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45158867
118Hedgehog signaling pathway_Homo sapiens_hsa043400.42950175
119Leukocyte transendothelial migration_Homo sapiens_hsa046700.42708623
120Retinol metabolism_Homo sapiens_hsa008300.42497894
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.42436791
122PI3K-Akt signaling pathway_Homo sapiens_hsa041510.42324258
123ErbB signaling pathway_Homo sapiens_hsa040120.42077670
124Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.41294568
125Salivary secretion_Homo sapiens_hsa049700.39422768
126Fat digestion and absorption_Homo sapiens_hsa049750.39384499
127Gastric acid secretion_Homo sapiens_hsa049710.39326758
128Tyrosine metabolism_Homo sapiens_hsa003500.36785246
129Salmonella infection_Homo sapiens_hsa051320.35823929
130Hippo signaling pathway_Homo sapiens_hsa043900.35024974
131Amoebiasis_Homo sapiens_hsa051460.34755908
132Maturity onset diabetes of the young_Homo sapiens_hsa049500.33951919
133Morphine addiction_Homo sapiens_hsa050320.33587534
134Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.33332446
135Bile secretion_Homo sapiens_hsa049760.32664282
136Primary bile acid biosynthesis_Homo sapiens_hsa001200.32519080
137Cocaine addiction_Homo sapiens_hsa050300.32188552
138Hepatitis C_Homo sapiens_hsa051600.30185294
139Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.30163104
140Gap junction_Homo sapiens_hsa045400.29815117
141Dopaminergic synapse_Homo sapiens_hsa047280.28171818
142Chemokine signaling pathway_Homo sapiens_hsa040620.28108294
143Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26892016
144Autoimmune thyroid disease_Homo sapiens_hsa053200.26208598

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