SLC51B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)7.69951230
2regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)7.40602573
3pantothenate metabolic process (GO:0015939)7.04968152
4macrophage chemotaxis (GO:0048246)6.65633386
5coenzyme A biosynthetic process (GO:0015937)6.55771215
6epoxygenase P450 pathway (GO:0019373)6.42030833
7NADH metabolic process (GO:0006734)6.13304830
8* bile acid and bile salt transport (GO:0015721)6.09649039
9negative regulation of protein tyrosine kinase activity (GO:0061099)6.09430899
10fat-soluble vitamin biosynthetic process (GO:0042362)5.78467410
11very-low-density lipoprotein particle assembly (GO:0034379)5.57356098
12maintenance of gastrointestinal epithelium (GO:0030277)5.43181480
13desmosome organization (GO:0002934)5.39553075
14purine nucleoside bisphosphate biosynthetic process (GO:0034033)5.32133170
15ribonucleoside bisphosphate biosynthetic process (GO:0034030)5.32133170
16nucleoside bisphosphate biosynthetic process (GO:0033866)5.32133170
17lymphocyte chemotaxis (GO:0048247)5.24969573
18plasma lipoprotein particle assembly (GO:0034377)5.17032559
19drug metabolic process (GO:0017144)5.05025939
20urea cycle (GO:0000050)4.95074488
21regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.88338565
22endocrine process (GO:0050886)4.88338565
23regulation of systemic arterial blood pressure by hormone (GO:0001990)4.88338565
24glycosylceramide metabolic process (GO:0006677)4.88324393
25pyrimidine-containing compound transmembrane transport (GO:0072531)4.83771002
26urea metabolic process (GO:0019627)4.79385878
27neurotransmitter biosynthetic process (GO:0042136)4.77271117
28vitamin transmembrane transport (GO:0035461)4.72752252
29fructose metabolic process (GO:0006000)4.69727826
30regulation of cholesterol esterification (GO:0010872)4.65755300
31hormone catabolic process (GO:0042447)4.65103432
32protein-lipid complex assembly (GO:0065005)4.64510594
33intestinal absorption (GO:0050892)4.61141601
34negative regulation of DNA repair (GO:0045738)4.60277637
35phosphatidylcholine biosynthetic process (GO:0006656)4.60155350
36high-density lipoprotein particle remodeling (GO:0034375)4.59566256
37negative regulation of receptor activity (GO:2000272)4.54137434
38neurotransmitter metabolic process (GO:0042133)4.46293736
39nitrogen cycle metabolic process (GO:0071941)4.40723387
40positive regulation of interleukin-1 secretion (GO:0050716)4.37205632
41epithelial structure maintenance (GO:0010669)4.35944473
42diacylglycerol metabolic process (GO:0046339)4.34371660
43regulation of systemic arterial blood pressure (GO:0003073)4.28712604
44coenzyme A metabolic process (GO:0015936)4.25492687
45regulation of cGMP biosynthetic process (GO:0030826)4.16712436
46plasma lipoprotein particle remodeling (GO:0034369)4.15717957
47protein-lipid complex remodeling (GO:0034368)4.15717957
48macromolecular complex remodeling (GO:0034367)4.15717957
49striated muscle atrophy (GO:0014891)4.06323038
50reverse cholesterol transport (GO:0043691)4.04736390
51regulation of interleukin-1 secretion (GO:0050704)4.04356432
52lipoprotein metabolic process (GO:0042157)4.03003834
53renal system process involved in regulation of blood volume (GO:0001977)4.01297071
54thrombin receptor signaling pathway (GO:0070493)3.98247726
55triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.97360856
56intestinal cholesterol absorption (GO:0030299)3.95346512
57glutamine family amino acid biosynthetic process (GO:0009084)3.92030748
58receptor guanylyl cyclase signaling pathway (GO:0007168)3.89338636
59sulfur amino acid catabolic process (GO:0000098)3.87122548
60response to hydroperoxide (GO:0033194)3.85576019
61regulation of bile acid biosynthetic process (GO:0070857)3.84525191
62oligosaccharide biosynthetic process (GO:0009312)3.84392988
63calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.83368162
64bile acid metabolic process (GO:0008206)3.80968773
65flavonoid metabolic process (GO:0009812)3.79729155
66drug transmembrane transport (GO:0006855)3.79379466
67digestion (GO:0007586)3.78016064
68positive regulation of lipid catabolic process (GO:0050996)3.77948807
69cholesterol efflux (GO:0033344)3.77552681
70regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.77043795
71plasma lipoprotein particle organization (GO:0071827)3.76288787
72angiotensin maturation (GO:0002003)3.74911663
73arginine metabolic process (GO:0006525)3.73582766
74drug catabolic process (GO:0042737)3.73291136
75alkaloid metabolic process (GO:0009820)3.71365867
76regulation of guanylate cyclase activity (GO:0031282)3.71167933
77ethanol oxidation (GO:0006069)3.67584288
78nucleoside bisphosphate metabolic process (GO:0033865)3.66718611
79purine nucleoside bisphosphate metabolic process (GO:0034032)3.66718611
80ribonucleoside bisphosphate metabolic process (GO:0033875)3.66718611
81renal absorption (GO:0070293)3.62757761
82artery development (GO:0060840)3.62267936
83regulation of cellular extravasation (GO:0002691)3.60473582
84skeletal muscle adaptation (GO:0043501)3.58678414
85bundle of His cell to Purkinje myocyte communication (GO:0086069)3.57701439
86phosphate ion transmembrane transport (GO:0035435)3.57559780
87cellular glucuronidation (GO:0052695)3.57037103
88protein-lipid complex subunit organization (GO:0071825)3.56170367
89fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.54082329
90exogenous drug catabolic process (GO:0042738)3.52637578
91regulation of vitamin metabolic process (GO:0030656)3.50976213
92virion attachment to host cell (GO:0019062)3.50358268
93adhesion of symbiont to host cell (GO:0044650)3.50358268
94vitamin A metabolic process (GO:0006776)3.49155489
95antibacterial humoral response (GO:0019731)3.47579074
96peptide hormone processing (GO:0016486)3.46985543
97regulation of metalloenzyme activity (GO:0048552)3.46276300
98cellular ketone body metabolic process (GO:0046950)3.45836139
99sulfur compound transport (GO:0072348)3.44125090
100fat-soluble vitamin metabolic process (GO:0006775)3.44112289
101lipoprotein transport (GO:0042953)3.42491277
102regulation of cGMP metabolic process (GO:0030823)3.41934117
103oligosaccharide catabolic process (GO:0009313)3.41751692
104L-ascorbic acid metabolic process (GO:0019852)3.40810403
105regulation of cholesterol homeostasis (GO:2000188)3.39365730
106regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.37718699
107vitamin biosynthetic process (GO:0009110)3.37343316
108acute-phase response (GO:0006953)3.36246416
109glycolipid catabolic process (GO:0019377)3.35043077
110regulation of triglyceride catabolic process (GO:0010896)3.34474566
111phosphate ion transport (GO:0006817)3.34427736
112modified amino acid transport (GO:0072337)3.34100430
113glycosphingolipid biosynthetic process (GO:0006688)3.33891227
114nitric oxide biosynthetic process (GO:0006809)3.33204672
115glycosphingolipid catabolic process (GO:0046479)3.32894207
116proline metabolic process (GO:0006560)3.32526324
117antimicrobial humoral response (GO:0019730)3.32404784
118sulfate transport (GO:0008272)3.32039575
119renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.31155481
120drinking behavior (GO:0042756)3.29701482
121muscle atrophy (GO:0014889)3.28983160
122drug transport (GO:0015893)3.28380805
123homocysteine metabolic process (GO:0050667)3.25764221
124positive regulation of respiratory burst (GO:0060267)3.25196427
125phenylpropanoid metabolic process (GO:0009698)3.24327156
126regulation of RIG-I signaling pathway (GO:0039535)3.24196014
127negative regulation of sterol transport (GO:0032372)3.23244505
128negative regulation of cholesterol transport (GO:0032375)3.23244505
129positive regulation of pseudopodium assembly (GO:0031274)3.23204242
130transepithelial transport (GO:0070633)3.22508246
131uronic acid metabolic process (GO:0006063)3.22257423
132glucuronate metabolic process (GO:0019585)3.22257423
133actin filament depolymerization (GO:0030042)3.18883581
134glycerol metabolic process (GO:0006071)3.17929871
135vitamin transport (GO:0051180)3.15186948
136low-density lipoprotein particle remodeling (GO:0034374)3.14811347
137peptidyl-tyrosine autophosphorylation (GO:0038083)3.14233521
138adhesion of symbiont to host (GO:0044406)3.13526133
139sodium ion homeostasis (GO:0055078)3.13240046
140cholesterol homeostasis (GO:0042632)3.12486528
141digestive system process (GO:0022600)3.10496381
142midgut development (GO:0007494)3.10480106
143sterol homeostasis (GO:0055092)3.09951840
144peptide catabolic process (GO:0043171)3.09533335
145positive regulation of guanylate cyclase activity (GO:0031284)3.09518823
146cytidine metabolic process (GO:0046087)3.09321428
147cytidine catabolic process (GO:0006216)3.09321428
148cytidine deamination (GO:0009972)3.09321428
149urate metabolic process (GO:0046415)3.09089120
150ganglioside metabolic process (GO:0001573)3.07366830
151positive regulation of interleukin-1 production (GO:0032732)3.06018909
152phospholipid efflux (GO:0033700)3.03322491
153alditol metabolic process (GO:0019400)3.01689373
154cysteine metabolic process (GO:0006534)2.99148003
155ketone body metabolic process (GO:1902224)2.98263006
1563-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.96189721
157purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.96189721
158positive regulation of lipoprotein lipase activity (GO:0051006)2.94141946
159positive regulation of triglyceride lipase activity (GO:0061365)2.94141946
160branching involved in labyrinthine layer morphogenesis (GO:0060670)2.93468149
161regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.92114199
162sulfate transmembrane transport (GO:1902358)2.86926411
163indole-containing compound catabolic process (GO:0042436)2.86227576
164indolalkylamine catabolic process (GO:0046218)2.86227576
165tryptophan catabolic process (GO:0006569)2.86227576
166regulation of histone phosphorylation (GO:0033127)2.82218939
167lysine metabolic process (GO:0006553)2.80955140
168lysine catabolic process (GO:0006554)2.80955140
169lymphocyte migration (GO:0072676)2.79788124

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.74391709
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.17987277
3RXR_22158963_ChIP-Seq_LIVER_Mouse3.44856405
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.23372000
5PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.21644199
6PPARA_22158963_ChIP-Seq_LIVER_Mouse3.13884410
7CDX2_20551321_ChIP-Seq_CACO-2_Human3.00117551
8SOX2_27498859_Chip-Seq_STOMACH_Mouse2.71836651
9LXR_22158963_ChIP-Seq_LIVER_Mouse2.71365810
10CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.61427866
11IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.45338903
12EGR1_23403033_ChIP-Seq_LIVER_Mouse2.45068306
13ZNF274_21170338_ChIP-Seq_K562_Hela2.38485532
14SOX2_20726797_ChIP-Seq_SW620_Human2.30956651
15CDX2_19796622_ChIP-Seq_MESCs_Mouse2.26238447
16THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.25736777
17NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.12038045
18FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.00566898
19ESR1_21235772_ChIP-Seq_MCF-7_Human1.91679467
20GATA6_25053715_ChIP-Seq_YYC3_Human1.86843576
21GATA4_25053715_ChIP-Seq_YYC3_Human1.85505986
22SRY_22984422_ChIP-ChIP_TESTIS_Rat1.84017032
23CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.82225052
24IRF8_22096565_ChIP-ChIP_GC-B_Human1.81877419
25IKZF1_21737484_ChIP-ChIP_HCT116_Human1.81583862
26NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.72056633
27TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.71673259
28ESR2_21235772_ChIP-Seq_MCF-7_Human1.71200594
29HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.66263634
30STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.65240587
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64733129
32AR_21909140_ChIP-Seq_LNCAP_Human1.63611488
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.63290895
34CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.61357335
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.60517125
36TRIM28_21343339_ChIP-Seq_HEK293_Human1.60084162
37CLOCK_20551151_ChIP-Seq_293T_Human1.59555206
38FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.59296601
39BP1_19119308_ChIP-ChIP_Hs578T_Human1.56097898
40ESR1_15608294_ChIP-ChIP_MCF-7_Human1.54069766
41NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.52464344
42ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.46735449
43BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.45566247
44BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.43190361
45CDX2_22108803_ChIP-Seq_LS180_Human1.38573568
46VDR_22108803_ChIP-Seq_LS180_Human1.36419046
47DROSHA_22980978_ChIP-Seq_HELA_Human1.32796879
48LXR_22292898_ChIP-Seq_THP-1_Human1.28659654
49KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.27051147
50KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.26201653
51FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.25872948
52KLF5_25053715_ChIP-Seq_YYC3_Human1.20666278
53RUNX1_27514584_Chip-Seq_MCF-7_Human1.20016736
54CEBPB_22108803_ChIP-Seq_LS180_Human1.19099292
55ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.18916515
56GATA1_22025678_ChIP-Seq_K562_Human1.14170663
57* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.13277126
58PPAR_26484153_Chip-Seq_NCI-H1993_Human1.12954278
59JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.12594883
60PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.11868459
61RACK7_27058665_Chip-Seq_MCF-7_Human1.11745063
62RAD21_21589869_ChIP-Seq_MESCs_Mouse1.10127364
63SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.09866453
64NANOG_20526341_ChIP-Seq_ESCs_Human1.08912044
65ATF3_27146783_Chip-Seq_COLON_Human1.08400649
66UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.07944096
67PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.07925246
68RXR_22108803_ChIP-Seq_LS180_Human1.06965718
69SA1_27219007_Chip-Seq_Bcells_Human1.06193799
70RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.06117685
71ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05577589
72TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03124133
73RARG_19884340_ChIP-ChIP_MEFs_Mouse1.02771579
74EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01203432
75CTCF_27219007_Chip-Seq_Bcells_Human1.00893693
76ETV2_25802403_ChIP-Seq_MESCs_Mouse0.98035300
77FOXO3_23340844_ChIP-Seq_DLD1_Human0.98021673
78TAF2_19829295_ChIP-Seq_ESCs_Human0.96780358
79SMC1_22415368_ChIP-Seq_MEFs_Mouse0.96250932
80SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.94689114
81TCF4_18268006_ChIP-ChIP_LS174T_Human0.94658430
82SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.93866244
83ERG_21242973_ChIP-ChIP_JURKAT_Human0.92857017
84ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.92177106
85SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.92168248
86SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.92081570
87EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91653242
88BCL6_27268052_Chip-Seq_Bcells_Human0.91187707
89BCOR_27268052_Chip-Seq_Bcells_Human0.90431229
90ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.90251040
91TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.89421600
92MYC_19915707_ChIP-ChIP_AK7_Human0.89271571
93TET1_21451524_ChIP-Seq_MESCs_Mouse0.89266463
94FOXA1_25552417_ChIP-Seq_VCAP_Human0.89262500
95SUZ12_27294783_Chip-Seq_ESCs_Mouse0.88760267
96SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.88678370
97NANOG_18692474_ChIP-Seq_MEFs_Mouse0.88339189
98KAP1_22055183_ChIP-Seq_ESCs_Mouse0.87307974
99JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86687567
100FOXA1_21572438_ChIP-Seq_LNCaP_Human0.86612042
101CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86561605
102HTT_18923047_ChIP-ChIP_STHdh_Human0.86188285
103TCF3_18692474_ChIP-Seq_MEFs_Mouse0.86117549
104SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.85665785
105P63_26484246_Chip-Seq_KERATINOCYTES_Human0.85403442
106FOXA2_19822575_ChIP-Seq_HepG2_Human0.85088303
107BCAT_22108803_ChIP-Seq_LS180_Human0.84979864
108GATA3_24758297_ChIP-Seq_MCF-7_Human0.84609848
109SOX2_22085726_ChIP-Seq_NPCs_Mouse0.84509923
110VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.83380597
111EZH2_27294783_Chip-Seq_ESCs_Mouse0.83291659
112GATA2_19941826_ChIP-Seq_K562_Human0.83185237
113AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.82701295
114KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.82216741
115GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.82015084
116SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.81532455
117HNF4A_19822575_ChIP-Seq_HepG2_Human0.81284129
118CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.80882343
119EGR1_19032775_ChIP-ChIP_M12_Human0.80781975
120ZNF263_19887448_ChIP-Seq_K562_Human0.80123552
121MTF2_20144788_ChIP-Seq_MESCs_Mouse0.80040160
122CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.79496451
123TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77719994
124SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.77535095
125GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.77318651
126FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.76925408
127OCT4_18692474_ChIP-Seq_MEFs_Mouse0.76699801
128SOX2_21211035_ChIP-Seq_LN229_Human0.76383224
129FOXM1_26456572_ChIP-Seq_MCF-7_Human0.75981576
130NR3C1_21868756_ChIP-Seq_MCF10A_Human0.75834611
131CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.75812017
132GATA1_19941826_ChIP-Seq_K562_Human0.75549120
133STAT1_20625510_ChIP-Seq_HELA_Human0.75288462
134PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.74984144
135P53_21459846_ChIP-Seq_SAOS-2_Human0.74605178
136AUTS2_25519132_ChIP-Seq_293T-REX_Human0.74234703
137Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.74080656
138HNFA_21074721_ChIP-Seq_CACO-2_Human0.73078659

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis6.24064128
2MP0002822_catalepsy4.58160977
3MP0003878_abnormal_ear_physiology3.86360503
4MP0005377_hearing/vestibular/ear_phenot3.86360503
5MP0003183_abnormal_peptide_metabolism3.44867696
6MP0002139_abnormal_hepatobiliary_system3.44180329
7MP0008875_abnormal_xenobiotic_pharmacok2.96805085
8MP0004147_increased_porphyrin_level2.96530439
9MP0005085_abnormal_gallbladder_physiolo2.80624428
10MP0003283_abnormal_digestive_organ2.70269602
11MP0001666_abnormal_nutrient_absorption2.62554692
12MP0009379_abnormal_foot_pigmentation2.57640633
13MP0005167_abnormal_blood-brain_barrier2.35590786
14MP0004264_abnormal_extraembryonic_tissu2.34839601
15MP0003191_abnormal_cellular_cholesterol2.30089431
16MP0003252_abnormal_bile_duct2.18235956
17MP0005257_abnormal_intraocular_pressure2.17163052
18MP0010234_abnormal_vibrissa_follicle11.0447939
19MP0010678_abnormal_skin_adnexa1.97334037
20MP0004019_abnormal_vitamin_homeostasis1.97172777
21MP0002876_abnormal_thyroid_physiology1.85547494
22MP0005365_abnormal_bile_salt1.85214743
23MP0000604_amyloidosis1.76474258
24MP0009643_abnormal_urine_homeostasis1.75762411
25MP0010329_abnormal_lipoprotein_level1.69448549
26MP0004043_abnormal_pH_regulation1.66656884
27MP0005409_darkened_coat_color1.66206808
28MP0005058_abnormal_lysosome_morphology1.63280701
29MP0003866_abnormal_defecation1.61908974
30MP0001764_abnormal_homeostasis1.58262428
31MP0003705_abnormal_hypodermis_morpholog1.56723735
32MP0005332_abnormal_amino_acid1.52747094
33MP0003806_abnormal_nucleotide_metabolis1.50201635
34MP0000013_abnormal_adipose_tissue1.47652104
35MP0002796_impaired_skin_barrier1.41196217
36MP0004185_abnormal_adipocyte_glucose1.33957151
37MP0003718_maternal_effect1.30003184
38MP0000462_abnormal_digestive_system1.27819075
39MP0005310_abnormal_salivary_gland1.14807809
40MP0001765_abnormal_ion_homeostasis1.13829712
41MP0005636_abnormal_mineral_homeostasis1.10530714
42MP0009840_abnormal_foam_cell1.10239522
43MP0000678_abnormal_parathyroid_gland1.09896917
44MP0002138_abnormal_hepatobiliary_system1.09112110
45MP0005319_abnormal_enzyme/_coenzyme1.09024352
46MP0002118_abnormal_lipid_homeostasis1.08839490
47MP0000477_abnormal_intestine_morphology1.07755448
48MP0005670_abnormal_white_adipose1.06083027
49MP0004947_skin_inflammation1.05956641
50MP0005076_abnormal_cell_differentiation1.02142139
51MP0001664_abnormal_digestion1.01676094
52MP0005448_abnormal_energy_balance0.98755029
53MP0002098_abnormal_vibrissa_morphology0.98342597
54MP0001663_abnormal_digestive_system0.97751317
55MP0003045_fibrosis0.97169672
56MP0005084_abnormal_gallbladder_morpholo0.96917685
57MP0001873_stomach_inflammation0.95185739
58MP0010155_abnormal_intestine_physiology0.93975053
59MP0005381_digestive/alimentary_phenotyp0.93843076
60MP0003453_abnormal_keratinocyte_physiol0.91851324
61MP0008872_abnormal_physiological_respon0.91543948
62MP0010352_gastrointestinal_tract_polyps0.90149941
63MP0000490_abnormal_crypts_of0.89316880
64MP0001188_hyperpigmentation0.88206189
65MP0001216_abnormal_epidermal_layer0.87505818
66MP0003300_gastrointestinal_ulcer0.86536255
67MP0005584_abnormal_enzyme/coenzyme_acti0.86472790
68MP0002909_abnormal_adrenal_gland0.86470068
69MP0009785_altered_susceptibility_to0.85350554
70MP0002136_abnormal_kidney_physiology0.84635354
71MP0001756_abnormal_urination0.84557254
72MP0000383_abnormal_hair_follicle0.80287418
73MP0000538_abnormal_urinary_bladder0.77826096
74MP0009115_abnormal_fat_cell0.77114577
75MP0005535_abnormal_body_temperature0.76718632
76MP0000377_abnormal_hair_follicle0.75435053
77MP0000427_abnormal_hair_cycle0.73580011
78MP0001501_abnormal_sleep_pattern0.73098691
79MP0005451_abnormal_body_composition0.72771162
80MP0008873_increased_physiological_sensi0.72668446
81MP0002971_abnormal_brown_adipose0.71715289
82MP0003195_calcinosis0.70740208
83MP0000566_synostosis0.69677408
84MP0001485_abnormal_pinna_reflex0.69600474
85MP0003329_amyloid_beta_deposits0.69204863
86MP0005666_abnormal_adipose_tissue0.68693859
87MP0003868_abnormal_feces_composition0.68059744
88MP0000609_abnormal_liver_physiology0.67852354
89MP0001845_abnormal_inflammatory_respons0.66393796
90MP0001849_ear_inflammation0.66275079
91MP0005501_abnormal_skin_physiology0.64365934
92MP0004858_abnormal_nervous_system0.62763987
93MP0003953_abnormal_hormone_level0.61965305
94MP0002148_abnormal_hypersensitivity_rea0.61538320
95MP0009053_abnormal_anal_canal0.59688327
96MP0000249_abnormal_blood_vessel0.59091279
97MP0003315_abnormal_perineum_morphology0.57611915
98MP0004782_abnormal_surfactant_physiolog0.56413648
99MP0002078_abnormal_glucose_homeostasis0.56283647
100MP0009642_abnormal_blood_homeostasis0.56032333
101MP0004270_analgesia0.55177619
102MP0003638_abnormal_response/metabolism_0.54433671
103MP0003724_increased_susceptibility_to0.54398627
104MP0009697_abnormal_copulation0.53827433
105MP0003075_altered_response_to0.52667777
106MP0002089_abnormal_postnatal_growth/wei0.49286403
107MP0005395_other_phenotype0.48084327
108MP0005083_abnormal_biliary_tract0.47556506
109MP0004272_abnormal_basement_membrane0.46814562
110MP0002166_altered_tumor_susceptibility0.46220680
111MP0004885_abnormal_endolymph0.45612143
112MP0009931_abnormal_skin_appearance0.44874365
113MP0000537_abnormal_urethra_morphology0.44712497
114MP0000762_abnormal_tongue_morphology0.43696868
115MP0005165_increased_susceptibility_to0.43321545
116MP0005376_homeostasis/metabolism_phenot0.43148016
117MP0005367_renal/urinary_system_phenotyp0.43128961
118MP0000516_abnormal_urinary_system0.43128961
119MP0003879_abnormal_hair_cell0.42611010
120MP0005166_decreased_susceptibility_to0.42401734
121MP0008469_abnormal_protein_level0.42401027
122MP0005334_abnormal_fat_pad0.42069649
123MP0000230_abnormal_systemic_arterial0.41879158
124MP0000598_abnormal_liver_morphology0.41691539
125MP0002234_abnormal_pharynx_morphology0.40805142
126MP0001243_abnormal_dermal_layer0.40007733
127MP0002896_abnormal_bone_mineralization0.37637177
128MP0005025_abnormal_response_to0.37475553
129MP0010030_abnormal_orbit_morphology0.37389870
130MP0003941_abnormal_skin_development0.37362683
131MP0006082_CNS_inflammation0.36068409
132MP0009764_decreased_sensitivity_to0.35969665
133MP0002069_abnormal_eating/drinking_beha0.35058441
134MP0005408_hypopigmentation0.33631535
135MP0000465_gastrointestinal_hemorrhage0.33293606
136MP0002135_abnormal_kidney_morphology0.31686021

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of small intestinal villus morphology (HP:0011472)6.01205639
2Villous atrophy (HP:0011473)6.01205639
3Abnormality of glutamine family amino acid metabolism (HP:0010902)5.22858307
4Malnutrition (HP:0004395)5.16065728
5Abnormality of the vitamin B12 metabolism (HP:0004341)4.89459012
6Abnormality of vitamin B metabolism (HP:0004340)4.58841045
7Acanthocytosis (HP:0001927)4.40597343
8Pili torti (HP:0003777)4.32138507
9Decreased circulating renin level (HP:0003351)4.26138537
10Ileus (HP:0002595)4.23483752
11Chronic diarrhea (HP:0002028)4.05234960
12Abnormality of vitamin metabolism (HP:0100508)3.97047656
13Systemic lupus erythematosus (HP:0002725)3.93457786
14Right ventricular cardiomyopathy (HP:0011663)3.91234615
15Pigmentary retinal degeneration (HP:0001146)3.84021125
16Flat acetabular roof (HP:0003180)3.82681139
17Hyperactive renin-angiotensin system (HP:0000841)3.79836604
18Metabolic alkalosis (HP:0200114)3.77456677
19Nausea (HP:0002018)3.75136569
20Prostate neoplasm (HP:0100787)3.69211619
21Increased purine levels (HP:0004368)3.69165789
22Hyperuricemia (HP:0002149)3.69165789
23Cupped ribs (HP:0000887)3.66182384
24Abnormality of purine metabolism (HP:0004352)3.56856331
25Xanthomatosis (HP:0000991)3.44776932
26Intrahepatic cholestasis (HP:0001406)3.35429587
27Gout (HP:0001997)3.31850654
28Congenital sensorineural hearing impairment (HP:0008527)3.11889661
29Vacuolated lymphocytes (HP:0001922)3.05312849
30Hyperglycinuria (HP:0003108)3.01361830
31Abnormality of monocarboxylic acid metabolism (HP:0010996)3.00528059
32Pustule (HP:0200039)2.97637557
33Wide cranial sutures (HP:0010537)2.95990375
34Abnormality of proline metabolism (HP:0010907)2.95273461
35Hydroxyprolinuria (HP:0003080)2.95273461
36Oligomenorrhea (HP:0000876)2.93527833
37Progressive sensorineural hearing impairment (HP:0000408)2.92888293
38Abnormality of pyrimidine metabolism (HP:0004353)2.91156134
39Steatorrhea (HP:0002570)2.87108182
40Proximal tubulopathy (HP:0000114)2.80399694
41Abnormality of carpal bone ossification (HP:0006257)2.78960953
42Abnormality of aspartate family amino acid metabolism (HP:0010899)2.77932189
43Hypoalphalipoproteinemia (HP:0003233)2.77431048
44Abnormality of chloride homeostasis (HP:0011422)2.77092904
45Hemorrhage of the eye (HP:0011885)2.76040212
46Facial shape deformation (HP:0011334)2.74540292
47Potter facies (HP:0002009)2.74540292
48Thin bony cortex (HP:0002753)2.74419639
49Congenital ichthyosiform erythroderma (HP:0007431)2.74334569
50Increased circulating renin level (HP:0000848)2.74078103
51Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.71516850
52Metabolic acidosis (HP:0001942)2.65627559
53Hypolipoproteinemia (HP:0010981)2.64006536
54Abnormality of the 1st metacarpal (HP:0010009)2.63330576
55Abnormal tarsal ossification (HP:0008369)2.59260221
56Arterial tortuosity (HP:0005116)2.57793942
57Epidermoid cyst (HP:0200040)2.56204077
58Hypophosphatemia (HP:0002148)2.56182622
59Abdominal distention (HP:0003270)2.54751997
60Abnormality of nucleobase metabolism (HP:0010932)2.53762433
61Abnormal urine phosphate concentration (HP:0012599)2.53404628
62Fat malabsorption (HP:0002630)2.52529331
63Abnormal hair laboratory examination (HP:0003328)2.51929485
64Widely patent fontanelles and sutures (HP:0004492)2.50585883
65Abnormality of sulfur amino acid metabolism (HP:0004339)2.49408244
66Alkalosis (HP:0001948)2.47832407
67Megaloblastic anemia (HP:0001889)2.47550236
68Dehydration (HP:0001944)2.47449052
69Hypomagnesemia (HP:0002917)2.46649434
70Hypobetalipoproteinemia (HP:0003563)2.46115092
71Abnormality of renin-angiotensin system (HP:0000847)2.45532726
72Hyperlipoproteinemia (HP:0010980)2.45466666
73Hyperphosphaturia (HP:0003109)2.44683782
74Delayed epiphyseal ossification (HP:0002663)2.43484168
75Hypokalemic alkalosis (HP:0001949)2.43020267
76Mildly elevated creatine phosphokinase (HP:0008180)2.42057354
77Progressive hearing impairment (HP:0001730)2.40236920
78Complement deficiency (HP:0004431)2.39616024
79Esophageal varix (HP:0002040)2.39102449
80Hypotension (HP:0002615)2.37581891
81Generalized aminoaciduria (HP:0002909)2.34559252
82Abnormality of magnesium homeostasis (HP:0004921)2.33813541
83Vascular tortuosity (HP:0004948)2.31570217
84Hoarse voice (HP:0001609)2.30804192
85Abnormality of serine family amino acid metabolism (HP:0010894)2.30708851
86Abnormality of glycine metabolism (HP:0010895)2.30708851
87Abnormality of the costochondral junction (HP:0000919)2.30652076
88Posterior subcapsular cataract (HP:0007787)2.30537450
89Glomerulonephritis (HP:0000099)2.30336299
90Symphalangism affecting the phalanges of the hand (HP:0009773)2.29802605
91Abnormality of fatty-acid metabolism (HP:0004359)2.27585276
92Glycosuria (HP:0003076)2.25519734
93Abnormality of urine glucose concentration (HP:0011016)2.25519734
94Nephrolithiasis (HP:0000787)2.24481619
95Hypoglycemic coma (HP:0001325)2.21888639
96Focal segmental glomerulosclerosis (HP:0000097)2.20734589
97Neonatal short-limb short stature (HP:0008921)2.20596854
98Hyperaldosteronism (HP:0000859)2.20545733
99Abnormality of complement system (HP:0005339)2.18124160
100Axonal loss (HP:0003447)2.17215518
101Biliary tract neoplasm (HP:0100574)2.16278870
102Hyperglycinemia (HP:0002154)2.16222913
103Enlarged epiphyses (HP:0010580)2.16199074
104Renal tubular acidosis (HP:0001947)2.15724160
105Curly hair (HP:0002212)2.14664910
106Colitis (HP:0002583)2.13755573
107Poikilocytosis (HP:0004447)2.12231901
108Abnormality of the 2nd finger (HP:0004100)2.11311539
109Hypokalemia (HP:0002900)2.10553982
110Abnormal ossification of hand bones (HP:0005921)2.09954642
111Abnormal urine output (HP:0012590)2.08499065
112Goiter (HP:0000853)2.07934669
113Abnormal hand bone ossification (HP:0010660)2.04581648
114Abnormality of the distal phalanx of the thumb (HP:0009617)2.04218870
115Abnormality of the proximal phalanges of the hand (HP:0009834)2.03820035
116Pancreatitis (HP:0001733)2.03613473
117Sensorimotor neuropathy (HP:0007141)2.03368314
118Deep venous thrombosis (HP:0002625)2.02377218
119Abnormality of aromatic amino acid family metabolism (HP:0004338)2.01937005
120Hyperparathyroidism (HP:0000843)2.01706234
121Cerebral palsy (HP:0100021)2.00944982
122Late onset (HP:0003584)2.00412056
123Abnormality of potassium homeostasis (HP:0011042)1.99867179
124Abnormality of the middle phalanges of the toes (HP:0010183)1.99436430
125Myopathic facies (HP:0002058)1.96909250
126Irritability (HP:0000737)1.96241160
127Hyperammonemia (HP:0001987)1.95951389
128Abnormality of renal excretion (HP:0011036)1.95111032
129Subcapsular cataract (HP:0000523)1.94753604
130Hypercholesterolemia (HP:0003124)1.94513317
131Renal tubular dysfunction (HP:0000124)1.93510184
132Lethargy (HP:0001254)1.92768704
133Ketoacidosis (HP:0001993)1.91711411
134Nephritis (HP:0000123)1.88455696
135Metaphyseal irregularity (HP:0003025)1.86295261
136Ventricular tachycardia (HP:0004756)1.85931019
137Confusion (HP:0001289)1.85858300
138Tetany (HP:0001281)1.85007680
139Dicarboxylic aciduria (HP:0003215)1.84610276
140Abnormality of dicarboxylic acid metabolism (HP:0010995)1.84610276
141Visceral angiomatosis (HP:0100761)1.84563272
142Neoplasm of the small intestine (HP:0100833)1.83950060
143Conjugated hyperbilirubinemia (HP:0002908)1.83768474
144Protuberant abdomen (HP:0001538)1.83404385
145Abnormal cartilage morphology (HP:0002763)1.83379907
146Vascular calcification (HP:0004934)1.82026249
147Abnormality of alkaline phosphatase activity (HP:0004379)1.80411043
148Glomerulosclerosis (HP:0000096)1.80059557
149Toxemia of pregnancy (HP:0100603)1.79600948
150Palpitations (HP:0001962)1.78292763

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PIK3CA9.21117597
2ACVR1B8.72488624
3MST1R8.24023421
4RIPK14.76964167
5FRK4.22985310
6MAP3K23.56088791
7MAP2K23.26587434
8KSR23.21338022
9MET2.97517110
10NME12.21397825
11TNIK1.93142848
12MAP3K141.57029652
13RIPK41.54960017
14CAMK2D1.38352847
15TAOK11.34523197
16MAP2K11.34474987
17STK241.30064323
18GRK61.29095177
19FGFR31.24086328
20MAP3K11.20143868
21MUSK1.19195023
22WNK41.18321234
23NLK1.18181095
24AKT31.12273877
25MAP3K121.08940559
26PTK21.05063251
27MAP3K111.04037513
28OXSR11.03986070
29DYRK1B1.01754553
30WNK31.01195964
31CASK0.98642229
32TYK20.95584140
33EPHA30.94043919
34MAP3K30.87913093
35MAP3K80.86803687
36TAOK20.86792125
37LMTK20.77565906
38GRK10.74109379
39ABL20.72751367
40MYLK0.71100783
41STK100.70665706
42MST40.68317019
43PDK10.64843961
44MAP2K30.61210529
45PRKCI0.58496233
46LATS10.55951122
47TESK10.53127984
48PRKG20.52970495
49CDC42BPA0.50245500
50RET0.49550390
51WNK10.48327970
52IRAK10.45119315
53TESK20.43994812
54BMPR20.43765086
55PRKCD0.42461195
56MELK0.41837829
57STK38L0.41289947
58EPHA20.41215139
59EPHB10.41136343
60ERN10.40781583
61PDGFRA0.40040997
62SGK2230.39391558
63SGK4940.39391558
64STK110.39137819
65STK390.38162987
66CDK90.37202927
67YES10.35852411
68BMX0.32591217
69EPHB20.32471966
70SRC0.32452755
71CHUK0.32295788
72ADRBK20.32046094
73TBK10.31915860
74SGK10.31633869
75PDK20.30413872
76PTK60.30170273
77PRKACA0.29850959
78TAOK30.28613218
79STK160.27723214
80MAPKAPK30.27636016
81STK380.26207735
82SGK20.25804043
83MAP4K10.25503728
84PRKCQ0.24004305
85CAMK2B0.23648486
86MAPK110.23430352
87EEF2K0.23270455
88IGF1R0.22928742
89BCKDK0.22802318
90JAK20.22438877
91PRKCA0.22366339
92CAMK2A0.22229428
93LYN0.22187999
94PRKCB0.22161036
95PRKG10.22131811
96PAK40.21601024
97MAPK150.21377730
98CDK60.21142134
99ZAK0.20567191
100SGK30.19920681
101STK30.18852623
102FGFR40.18699640
103ITK0.18326023
104CAMK2G0.17729907
105PAK20.16715180
106MARK30.14024283
107DDR20.13588140
108PIK3CG0.13337511
109MATK0.13200476
110CSK0.12266916
111PRKACG0.12143707
112PIM10.11360234
113KDR0.10812162
114DAPK30.10456495
115IKBKE0.09837048
116GSK3A0.09299181
117PRKCZ0.09035574
118RPS6KA10.09002084
119DMPK0.08526779
120MAPK40.08149580
121CSNK1E0.08056870
122TTN0.07381572
123PTK2B0.07112912
124FYN0.07031128
125LIMK10.06423390
126FER0.05980173
127MAP2K60.05573235
128RPS6KB20.05431235
129CSNK1A10.05420481
130ERBB40.05124133
131EPHA40.05068094
132ERBB20.04473630
133PDPK10.04037388
134PRKAA20.03439665
135MAP3K100.03009430
136ROCK20.02938669

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009204.53441775
2Pantothenate and CoA biosynthesis_Homo sapiens_hsa007704.26868573
3Mineral absorption_Homo sapiens_hsa049783.61460956
4Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.76084285
5Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.73828930
6* Bile secretion_Homo sapiens_hsa049762.68366160
7Fat digestion and absorption_Homo sapiens_hsa049752.68120083
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.32039343
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.19062839
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.13737126
11Renin-angiotensin system_Homo sapiens_hsa046142.08371065
12Butanoate metabolism_Homo sapiens_hsa006501.91854526
13Vitamin digestion and absorption_Homo sapiens_hsa049771.80521039
14PPAR signaling pathway_Homo sapiens_hsa033201.75050105
15Tryptophan metabolism_Homo sapiens_hsa003801.73688507
16Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.68841972
17Arginine biosynthesis_Homo sapiens_hsa002201.67904907
18Pentose and glucuronate interconversions_Homo sapiens_hsa000401.64430057
19Glycerolipid metabolism_Homo sapiens_hsa005611.58006958
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.42321139
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.41021083
22Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.40235793
23Histidine metabolism_Homo sapiens_hsa003401.37274905
24Fatty acid degradation_Homo sapiens_hsa000711.33515542
25Starch and sucrose metabolism_Homo sapiens_hsa005001.32748114
26Protein digestion and absorption_Homo sapiens_hsa049741.31218125
27Sulfur relay system_Homo sapiens_hsa041221.30061853
28Maturity onset diabetes of the young_Homo sapiens_hsa049501.28411888
29Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.27259834
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.25165825
31Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.22045295
32Nitrogen metabolism_Homo sapiens_hsa009101.17455801
33Primary bile acid biosynthesis_Homo sapiens_hsa001201.17245419
34Galactose metabolism_Homo sapiens_hsa000521.14721563
35Caffeine metabolism_Homo sapiens_hsa002321.14718459
36Cyanoamino acid metabolism_Homo sapiens_hsa004601.12999847
37Fructose and mannose metabolism_Homo sapiens_hsa000511.08430922
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07487261
39Tight junction_Homo sapiens_hsa045301.03472382
40Glutathione metabolism_Homo sapiens_hsa004801.03431763
41Salivary secretion_Homo sapiens_hsa049701.00590235
42Chemical carcinogenesis_Homo sapiens_hsa052040.98000395
43Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.95068380
44Folate biosynthesis_Homo sapiens_hsa007900.92662862
45Fatty acid metabolism_Homo sapiens_hsa012120.92076373
46Glycosaminoglycan degradation_Homo sapiens_hsa005310.91677660
47Ether lipid metabolism_Homo sapiens_hsa005650.91098018
48Carbohydrate digestion and absorption_Homo sapiens_hsa049730.90765238
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.87783767
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.85422585
51Pyruvate metabolism_Homo sapiens_hsa006200.84573213
52Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.82575047
53Peroxisome_Homo sapiens_hsa041460.77860931
54Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76417356
55Propanoate metabolism_Homo sapiens_hsa006400.74673885
56Salmonella infection_Homo sapiens_hsa051320.74435486
57Arginine and proline metabolism_Homo sapiens_hsa003300.74071321
58Tyrosine metabolism_Homo sapiens_hsa003500.72819474
59Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71910552
60beta-Alanine metabolism_Homo sapiens_hsa004100.70228146
61ABC transporters_Homo sapiens_hsa020100.69333536
62Thyroid hormone synthesis_Homo sapiens_hsa049180.68454964
63alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67250495
64Carbon metabolism_Homo sapiens_hsa012000.66734727
65Thyroid cancer_Homo sapiens_hsa052160.65549639
66Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.65405282
67Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65000238
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64994626
69Fatty acid elongation_Homo sapiens_hsa000620.60627459
70Hepatitis C_Homo sapiens_hsa051600.59569588
71Sphingolipid metabolism_Homo sapiens_hsa006000.57195967
72Asthma_Homo sapiens_hsa053100.55410921
73Linoleic acid metabolism_Homo sapiens_hsa005910.54395677
74Pancreatic secretion_Homo sapiens_hsa049720.52073518
75Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.51248766
76Leishmaniasis_Homo sapiens_hsa051400.49815431
77Intestinal immune network for IgA production_Homo sapiens_hsa046720.49688562
78Bladder cancer_Homo sapiens_hsa052190.48958431
79Fatty acid biosynthesis_Homo sapiens_hsa000610.47176936
80Type II diabetes mellitus_Homo sapiens_hsa049300.45861713
81Staphylococcus aureus infection_Homo sapiens_hsa051500.45188886
82Drug metabolism - other enzymes_Homo sapiens_hsa009830.45146652
83Phenylalanine metabolism_Homo sapiens_hsa003600.44366067
84Retinol metabolism_Homo sapiens_hsa008300.44285027
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43227253
86Glycerophospholipid metabolism_Homo sapiens_hsa005640.41905316
87Choline metabolism in cancer_Homo sapiens_hsa052310.40884196
88Complement and coagulation cascades_Homo sapiens_hsa046100.39989254
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.39549856
90Other glycan degradation_Homo sapiens_hsa005110.38718251
91Pentose phosphate pathway_Homo sapiens_hsa000300.37861373
92Alzheimers disease_Homo sapiens_hsa050100.37561292
93Selenocompound metabolism_Homo sapiens_hsa004500.36497706
94Leukocyte transendothelial migration_Homo sapiens_hsa046700.35363448
95Oxidative phosphorylation_Homo sapiens_hsa001900.33479102
96Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.31894948
97Metabolic pathways_Homo sapiens_hsa011000.31523643
98Pertussis_Homo sapiens_hsa051330.31193945
99Chronic myeloid leukemia_Homo sapiens_hsa052200.29951965
100Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.29267345
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27628388
102Prion diseases_Homo sapiens_hsa050200.26131491
103Biosynthesis of amino acids_Homo sapiens_hsa012300.24050617
104Allograft rejection_Homo sapiens_hsa053300.23467194
105Renin secretion_Homo sapiens_hsa049240.22184903
106Parkinsons disease_Homo sapiens_hsa050120.21953462
107Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.21478008
108Insulin resistance_Homo sapiens_hsa049310.20813635
109Gastric acid secretion_Homo sapiens_hsa049710.20752101
110Arachidonic acid metabolism_Homo sapiens_hsa005900.20073012
111Autoimmune thyroid disease_Homo sapiens_hsa053200.20011771
112African trypanosomiasis_Homo sapiens_hsa051430.18907203
113Graft-versus-host disease_Homo sapiens_hsa053320.17428868
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.15739423
115Ovarian steroidogenesis_Homo sapiens_hsa049130.08329551
116Type I diabetes mellitus_Homo sapiens_hsa049400.07327592
117Glucagon signaling pathway_Homo sapiens_hsa049220.05370499
118Serotonergic synapse_Homo sapiens_hsa047260.03367306
119Cocaine addiction_Homo sapiens_hsa050300.02477093
120Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321-0.0674923
121Insulin secretion_Homo sapiens_hsa04911-0.0539322

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