SLC5A3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.19536794
2metanephric nephron tubule development (GO:0072234)4.55717759
3metanephric tubule development (GO:0072170)4.55717759
4regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)4.51219810
5nuclear pore organization (GO:0006999)4.49313942
6axon ensheathment in central nervous system (GO:0032291)4.24974899
7central nervous system myelination (GO:0022010)4.24974899
8metanephric nephron epithelium development (GO:0072243)4.22692739
9regulation of transforming growth factor beta2 production (GO:0032909)4.13951052
10regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)4.00812016
11metanephric epithelium development (GO:0072207)3.94642507
12mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.87004288
13pore complex assembly (GO:0046931)3.80660495
14mitotic sister chromatid cohesion (GO:0007064)3.67299420
15* polyol transport (GO:0015791)3.62240130
16import into cell (GO:0098657)3.60317451
17positive regulation of catenin import into nucleus (GO:0035413)3.53017516
18glomerular visceral epithelial cell development (GO:0072015)3.50904341
19excretion (GO:0007588)3.48710969
20apoptotic cell clearance (GO:0043277)3.48331602
21phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.46093937
22collecting duct development (GO:0072044)3.38213762
23phospholipid translocation (GO:0045332)3.33168292
24lipid translocation (GO:0034204)3.33168292
25interkinetic nuclear migration (GO:0022027)3.32982960
26genitalia morphogenesis (GO:0035112)3.26643013
27presynaptic membrane assembly (GO:0097105)3.17006601
28nephron tubule development (GO:0072080)3.16441975
29negative regulation of DNA repair (GO:0045738)3.15868420
30dorsal/ventral axis specification (GO:0009950)3.15112939
31response to lipoprotein particle (GO:0055094)3.15025885
32negative chemotaxis (GO:0050919)3.13883126
33establishment of nucleus localization (GO:0040023)3.11166001
34regulation of nephron tubule epithelial cell differentiation (GO:0072182)3.07665048
35nucleus localization (GO:0051647)3.03623611
36glomerular basement membrane development (GO:0032836)3.03070401
37negative regulation of neurotransmitter transport (GO:0051589)3.00414842
38limb bud formation (GO:0060174)2.99244874
39presynaptic membrane organization (GO:0097090)2.96944527
40morphogenesis of an epithelial sheet (GO:0002011)2.96140984
41nephron epithelium development (GO:0072009)2.95446150
42cell adhesion mediated by integrin (GO:0033627)2.93950963
43glomerular epithelial cell development (GO:0072310)2.92199806
44positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.91088716
45diterpenoid biosynthetic process (GO:0016102)2.81216183
46cytoplasmic mRNA processing body assembly (GO:0033962)2.79681769
47positive regulation of osteoblast proliferation (GO:0033690)2.79416617
48regulation of epithelial cell differentiation involved in kidney development (GO:2000696)2.78441119
49cellular response to ethanol (GO:0071361)2.78383576
50neuron cell-cell adhesion (GO:0007158)2.78082518
51one-carbon compound transport (GO:0019755)2.77858033
52SMAD protein complex assembly (GO:0007183)2.77442131
53substrate-dependent cell migration (GO:0006929)2.76027728
54melanin metabolic process (GO:0006582)2.74643168
55renal tubule development (GO:0061326)2.71487270
56pre-miRNA processing (GO:0031054)2.71405012
57negative regulation of neurotransmitter secretion (GO:0046929)2.69316585
58monoubiquitinated protein deubiquitination (GO:0035520)2.69244897
59extracellular matrix assembly (GO:0085029)2.68997125
60pericardium development (GO:0060039)2.68746143
61embryonic foregut morphogenesis (GO:0048617)2.68286523
62long-chain fatty acid biosynthetic process (GO:0042759)2.67431646
63retina vasculature morphogenesis in camera-type eye (GO:0061299)2.67350886
64renal absorption (GO:0070293)2.65462513
65regulation of Rac protein signal transduction (GO:0035020)2.61954602
66regulation of protein polyubiquitination (GO:1902914)2.61536137
67nerve growth factor signaling pathway (GO:0038180)2.60968478
68fatty acid elongation (GO:0030497)2.60901110
69chondrocyte proliferation (GO:0035988)2.60003434
70neuron projection extension involved in neuron projection guidance (GO:1902284)2.59862639
71axon extension involved in axon guidance (GO:0048846)2.59862639
72endodermal cell differentiation (GO:0035987)2.59349233
73substrate adhesion-dependent cell spreading (GO:0034446)2.58620787
74neuron remodeling (GO:0016322)2.56932852
75membrane assembly (GO:0071709)2.55947936
76hippo signaling (GO:0035329)2.55767466
77paraxial mesoderm development (GO:0048339)2.54977369
78protein targeting to lysosome (GO:0006622)2.54789578
79establishment of protein localization to vacuole (GO:0072666)2.54789578
80protein targeting to vacuole (GO:0006623)2.54789578
81negative regulation of keratinocyte proliferation (GO:0010839)2.54748529
82dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.54536459
83myelination (GO:0042552)2.54166205
84melanin biosynthetic process (GO:0042438)2.51228299
85iron ion import (GO:0097286)2.50562389
86regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.49062889
87regulation of apoptotic cell clearance (GO:2000425)2.48669718
88fibroblast migration (GO:0010761)2.48430213
89platelet-derived growth factor receptor signaling pathway (GO:0048008)2.48174080
90pigment cell differentiation (GO:0050931)2.47303788
91axon ensheathment (GO:0008366)2.47124645
92ensheathment of neurons (GO:0007272)2.47124645
93mitotic cytokinesis (GO:0000281)2.46768232
94cytoskeleton-dependent cytokinesis (GO:0061640)2.46650683
95embryonic retina morphogenesis in camera-type eye (GO:0060059)2.46367056
96calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.46205982
97regulation of pigment cell differentiation (GO:0050932)2.46091394
98astrocyte development (GO:0014002)2.46059360
99myelin assembly (GO:0032288)2.45367819
100Golgi to endosome transport (GO:0006895)2.44220918
101mammary gland alveolus development (GO:0060749)2.44028274
102chondrocyte development (GO:0002063)2.43847079
103ERK1 and ERK2 cascade (GO:0070371)2.42071573
104postsynaptic membrane organization (GO:0001941)2.42036199
105bone remodeling (GO:0046849)2.41317404
106renal tubule morphogenesis (GO:0061333)2.41191322
107regulation of axon extension involved in axon guidance (GO:0048841)2.40540965
108anatomical structure arrangement (GO:0048532)2.39731094
109positive regulation of glycoprotein biosynthetic process (GO:0010560)2.39639489
110asymmetric protein localization (GO:0008105)2.39517300
111UDP-N-acetylglucosamine metabolic process (GO:0006047)2.38842561
112mesenchymal-epithelial cell signaling (GO:0060638)2.37643556
113embryonic eye morphogenesis (GO:0048048)2.36889292
114NLS-bearing protein import into nucleus (GO:0006607)2.36184347
115righting reflex (GO:0060013)2.35727135
116glomerular filtration (GO:0003094)2.35566722
117positive regulation of synapse assembly (GO:0051965)2.35061544
118melanocyte differentiation (GO:0030318)2.34930825
119regulation of centriole replication (GO:0046599)2.34341793
120neuron recognition (GO:0008038)2.34190851
121nephron tubule formation (GO:0072079)2.33900175
122kidney mesenchyme development (GO:0072074)2.33892201
123regulation of sister chromatid cohesion (GO:0007063)2.32899534
124cerebral cortex radially oriented cell migration (GO:0021799)2.32839278
125negative regulation of fibroblast apoptotic process (GO:2000270)2.32541333
126regulation of hippo signaling (GO:0035330)2.32338733
127sequestering of extracellular ligand from receptor (GO:0035581)2.31797728
128oligosaccharide catabolic process (GO:0009313)2.31512846
129dendrite morphogenesis (GO:0048813)2.31398752
130positive regulation of developmental pigmentation (GO:0048087)2.29356332
131potassium ion import (GO:0010107)2.29254361
132axonal fasciculation (GO:0007413)2.29043772
133embryonic camera-type eye morphogenesis (GO:0048596)2.28935266
134regulation of centrosome duplication (GO:0010824)2.28758258
135startle response (GO:0001964)2.28435125
136protein K11-linked deubiquitination (GO:0035871)2.26627803
137activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.26485979
138lung epithelium development (GO:0060428)2.26243925
139gastrulation with mouth forming second (GO:0001702)2.25425374
140metanephric mesenchyme development (GO:0072075)2.25380681
141regulation of non-canonical Wnt signaling pathway (GO:2000050)2.24954726
142camera-type eye morphogenesis (GO:0048593)2.24939377
143regulation of mesenchymal cell proliferation (GO:0010464)2.23903567
144protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.22982087
145collagen fibril organization (GO:0030199)2.22950561
146eye photoreceptor cell differentiation (GO:0001754)2.22678571
147photoreceptor cell differentiation (GO:0046530)2.22678571
148negative regulation of chondrocyte differentiation (GO:0032331)2.22526641
149magnesium ion transport (GO:0015693)2.21974904
150positive regulation of mesenchymal cell proliferation (GO:0002053)2.21374615
151craniofacial suture morphogenesis (GO:0097094)2.21361575
152regulation of axon guidance (GO:1902667)2.21274687
153regulation of RNA export from nucleus (GO:0046831)2.21116249
154nephron tubule morphogenesis (GO:0072078)2.21040602
155nephron epithelium morphogenesis (GO:0072088)2.21040602
156long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.20346671
157apical protein localization (GO:0045176)2.20223607
158cranial nerve structural organization (GO:0021604)2.19788702
159renal filtration (GO:0097205)2.19663836
160regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.19200401
161L-amino acid import (GO:0043092)2.18773640
162myelin maintenance (GO:0043217)2.18130337
163protein localization to cell surface (GO:0034394)2.17661831
164regulation of potassium ion transmembrane transporter activity (GO:1901016)2.17342610
165positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.17220601
166regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.17112694
167negative regulation of synaptic transmission, GABAergic (GO:0032229)2.16543699
168smooth muscle tissue development (GO:0048745)2.15843685
169clathrin coat assembly (GO:0048268)2.11204671
170negative regulation of axon extension involved in axon guidance (GO:0048843)2.10749820
171membrane repolarization during action potential (GO:0086011)2.10258587
172vascular smooth muscle contraction (GO:0014829)2.10211173
173vocalization behavior (GO:0071625)2.10179996
174negative regulation of protein localization to cell surface (GO:2000009)2.09004833
175protein heterotrimerization (GO:0070208)2.08402830
176regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.08144134
177insulin-like growth factor receptor signaling pathway (GO:0048009)2.07982090
178artery development (GO:0060840)2.07392895
179L-serine transport (GO:0015825)2.06101402
180myelination in peripheral nervous system (GO:0022011)2.05994850
181peripheral nervous system axon ensheathment (GO:0032292)2.05994850
182chloride transmembrane transport (GO:1902476)2.05232714
183artery smooth muscle contraction (GO:0014824)2.04923258
184tonic smooth muscle contraction (GO:0014820)2.04645004
185negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.04039776
186long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.03098286
187regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.02951086

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SALL1_21062744_ChIP-ChIP_HESCs_Human3.22493785
2GBX2_23144817_ChIP-Seq_PC3_Human3.11503636
3AR_21572438_ChIP-Seq_LNCaP_Human2.57327977
4EZH2_22144423_ChIP-Seq_EOC_Human2.47854497
5GATA1_22025678_ChIP-Seq_K562_Human2.31454858
6CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.28884654
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.27392019
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.24299099
9EED_16625203_ChIP-ChIP_MESCs_Mouse2.24005362
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.20857905
11CDX2_19796622_ChIP-Seq_MESCs_Mouse2.19219501
12TAF15_26573619_Chip-Seq_HEK293_Human2.15489621
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.12829174
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.11236756
15TRIM28_21343339_ChIP-Seq_HEK293_Human2.10000254
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.06084864
17RNF2_18974828_ChIP-Seq_MESCs_Mouse2.06084864
18PIAS1_25552417_ChIP-Seq_VCAP_Human2.04496254
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.03846401
20EZH2_27304074_Chip-Seq_ESCs_Mouse1.98079803
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.95620349
22* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.95613995
23POU3F2_20337985_ChIP-ChIP_501MEL_Human1.91708677
24SMAD_19615063_ChIP-ChIP_OVARY_Human1.90245047
25* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.88350120
26ZFP57_27257070_Chip-Seq_ESCs_Mouse1.86599030
27BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.86029449
28RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.82106242
29JARID2_20075857_ChIP-Seq_MESCs_Mouse1.80272508
30ZNF217_24962896_ChIP-Seq_MCF-7_Human1.78818746
31Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.78390345
32WT1_19549856_ChIP-ChIP_CCG9911_Human1.76134956
33MTF2_20144788_ChIP-Seq_MESCs_Mouse1.71088192
34AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.70780249
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69632831
36P300_19829295_ChIP-Seq_ESCs_Human1.67944360
37ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.67508824
38TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.67161510
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.66603263
40BRD4_25478319_ChIP-Seq_HGPS_Human1.66179607
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.64078792
42KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.63802609
43SALL4_18804426_ChIP-ChIP_XEN_Mouse1.59967262
44SMAD4_21799915_ChIP-Seq_A2780_Human1.59592605
45TP53_18474530_ChIP-ChIP_U2OS_Human1.58223227
46NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.56967937
47NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.53620969
48NRF2_20460467_ChIP-Seq_MEFs_Mouse1.53620969
49SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.52771551
50ER_23166858_ChIP-Seq_MCF-7_Human1.52093564
51TP53_16413492_ChIP-PET_HCT116_Human1.51961332
52RNF2_27304074_Chip-Seq_ESCs_Mouse1.50752895
53EP300_21415370_ChIP-Seq_HL-1_Mouse1.50440362
54CBX2_27304074_Chip-Seq_ESCs_Mouse1.49467228
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.48249490
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.47421303
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.47291588
58CTNNB1_20460455_ChIP-Seq_HCT116_Human1.46939214
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.46532130
60CTBP1_25329375_ChIP-Seq_LNCAP_Human1.44884023
61ARNT_22903824_ChIP-Seq_MCF-7_Human1.44872100
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.43593379
63TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.43265396
64GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42181409
65IGF1R_20145208_ChIP-Seq_DFB_Human1.41540013
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.41392864
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.40895748
68CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.40839888
69AHR_22903824_ChIP-Seq_MCF-7_Human1.38895638
70NR3C1_21868756_ChIP-Seq_MCF10A_Human1.37160277
71CJUN_26792858_Chip-Seq_BT549_Human1.34669580
72FUS_26573619_Chip-Seq_HEK293_Human1.34279708
73EZH2_27294783_Chip-Seq_ESCs_Mouse1.34249814
74* SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.34013435
75SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.32311057
76SUZ12_27294783_Chip-Seq_ESCs_Mouse1.31863221
77ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.31753945
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.28825320
79TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.28615107
80PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.27010926
81STAT3_23295773_ChIP-Seq_U87_Human1.25893013
82RXR_22108803_ChIP-Seq_LS180_Human1.25877204
83AR_21909140_ChIP-Seq_LNCAP_Human1.25382340
84TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23960285
85PPAR_26484153_Chip-Seq_NCI-H1993_Human1.23543476
86AR_25329375_ChIP-Seq_VCAP_Human1.23176363
87FLI1_27457419_Chip-Seq_LIVER_Mouse1.21927288
88UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20382116
89CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.19633628
90BCAT_22108803_ChIP-Seq_LS180_Human1.18817587
91SUZ12_18555785_Chip-Seq_ESCs_Mouse1.18556542
92NANOG_18555785_Chip-Seq_ESCs_Mouse1.18516330
93RBPJ_22232070_ChIP-Seq_NCS_Mouse1.18390862
94FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.18163946
95CMYC_18555785_Chip-Seq_ESCs_Mouse1.18110233
96RUNX2_22187159_ChIP-Seq_PCA_Human1.17726803
97PCGF2_27294783_Chip-Seq_ESCs_Mouse1.17361470
98PRDM14_20953172_ChIP-Seq_ESCs_Human1.17259751
99FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.17205217
100FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.16480520
101P53_22387025_ChIP-Seq_ESCs_Mouse1.16101351
102RNF2_27304074_Chip-Seq_NSC_Mouse1.15968694
103FOXM1_23109430_ChIP-Seq_U2OS_Human1.15736129
104* TP63_23658742_ChIP-Seq_EP156T_Human1.13376652
105CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.13060303
106RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12556195
107TCF4_23295773_ChIP-Seq_U87_Human1.12415055
108TBX3_20139965_ChIP-Seq_MESCs_Mouse1.11883657
109E2F7_22180533_ChIP-Seq_HELA_Human1.11837364
110EWS_26573619_Chip-Seq_HEK293_Human1.11823259
111TBX3_20139965_ChIP-Seq_ESCs_Mouse1.11796514
112SOX2_21211035_ChIP-Seq_LN229_Gbm1.10928240
113PCGF2_27294783_Chip-Seq_NPCs_Mouse1.10797894
114NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10540364
115FOXO3_23340844_ChIP-Seq_DLD1_Human1.09872474
116RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.07661302
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06694526
118EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06098136
119E2F1_18555785_Chip-Seq_ESCs_Mouse1.05655200
120FOXM1_26456572_ChIP-Seq_MCF-7_Human1.05390049
121ESR1_20079471_ChIP-ChIP_T-47D_Human1.05374078
122SOX9_24532713_ChIP-Seq_HFSC_Mouse1.04868701
123VDR_22108803_ChIP-Seq_LS180_Human1.04780455
124STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.03615913
125YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03533558
126DROSHA_22980978_ChIP-Seq_HELA_Human1.03257691
127TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02809862
128TCF4_18268006_ChIP-ChIP_LS174T_Human1.02736727
129PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.01810929
130RING1B_27294783_Chip-Seq_NPCs_Mouse1.01782185
131HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.01207500
132MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00714272
133P300_18555785_Chip-Seq_ESCs_Mouse1.00620348
134CDX2_22108803_ChIP-Seq_LS180_Human0.99618716
135NFE2_27457419_Chip-Seq_LIVER_Mouse0.99357238
136SOX2_18555785_Chip-Seq_ESCs_Mouse0.99347711
137SUZ12_27294783_Chip-Seq_NPCs_Mouse0.98967405
138BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.98925254

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication3.94055054
2MP0005257_abnormal_intraocular_pressure3.77012601
3MP0004043_abnormal_pH_regulation3.68444093
4MP0008438_abnormal_cutaneous_collagen3.37688157
5MP0010352_gastrointestinal_tract_polyps3.23147799
6MP0005248_abnormal_Harderian_gland3.17927202
7MP0004272_abnormal_basement_membrane3.07294452
8MP0005623_abnormal_meninges_morphology2.95099540
9MP0003300_gastrointestinal_ulcer2.84058311
10MP0003890_abnormal_embryonic-extraembry2.50746361
11MP0005171_absent_coat_pigmentation2.50245125
12MP0002877_abnormal_melanocyte_morpholog2.50060674
13MP0005503_abnormal_tendon_morphology2.49991016
14MP0001958_emphysema2.35324038
15MP0004742_abnormal_vestibular_system2.16635121
16MP0000371_diluted_coat_color2.05895960
17MP0003880_abnormal_central_pattern2.03948097
18MP0005408_hypopigmentation1.99076126
19MP0003941_abnormal_skin_development1.96621819
20MP0003195_calcinosis1.96087047
21MP0003136_yellow_coat_color1.95115832
22MP0003950_abnormal_plasma_membrane1.91614796
23MP0008004_abnormal_stomach_pH1.90714635
24MP0003045_fibrosis1.89354552
25MP0000920_abnormal_myelination1.80091509
26MP0010234_abnormal_vibrissa_follicle1.79089410
27MP0000778_abnormal_nervous_system1.78302526
28MP0001756_abnormal_urination1.78171899
29MP0009250_abnormal_appendicular_skeleto1.76883980
30MP0001765_abnormal_ion_homeostasis1.76011593
31MP0001299_abnormal_eye_distance/1.71129706
32MP0003705_abnormal_hypodermis_morpholog1.70942055
33MP0009780_abnormal_chondrocyte_physiolo1.69860777
34MP0002168_other_aberrant_phenotype1.69627155
35MP0005197_abnormal_uvea_morphology1.68013652
36MP0002108_abnormal_muscle_morphology1.66114100
37MP0005187_abnormal_penis_morphology1.64454443
38MP0005275_abnormal_skin_tensile1.61230818
39MP0001188_hyperpigmentation1.57581388
40MP0001324_abnormal_eye_pigmentation1.56708112
41MP0004885_abnormal_endolymph1.54967531
42MP0010307_abnormal_tumor_latency1.54128082
43MP0000428_abnormal_craniofacial_morphol1.50570369
44MP0001915_intracranial_hemorrhage1.50158651
45MP0006054_spinal_hemorrhage1.47676210
46MP0004270_analgesia1.47178672
47MP0001486_abnormal_startle_reflex1.45451884
48MP0000566_synostosis1.45305939
49MP0002876_abnormal_thyroid_physiology1.44986786
50MP0002075_abnormal_coat/hair_pigmentati1.38889493
51MP0002009_preneoplasia1.37219358
52MP0005409_darkened_coat_color1.35004005
53MP0009384_cardiac_valve_regurgitation1.34397296
54MP0004134_abnormal_chest_morphology1.32984104
55MP0002092_abnormal_eye_morphology1.32893651
56MP0003690_abnormal_glial_cell1.29727324
57MP0000432_abnormal_head_morphology1.28752617
58MP0005076_abnormal_cell_differentiation1.26544512
59MP0000534_abnormal_ureter_morphology1.26430448
60MP0000647_abnormal_sebaceous_gland1.26427056
61MP0003935_abnormal_craniofacial_develop1.24780227
62MP0002697_abnormal_eye_size1.24393552
63MP0010678_abnormal_skin_adnexa1.23371133
64MP0005174_abnormal_tail_pigmentation1.22470720
65MP0000015_abnormal_ear_pigmentation1.22309650
66MP0009046_muscle_twitch1.19422047
67MP0003937_abnormal_limbs/digits/tail_de1.19245452
68MP0002896_abnormal_bone_mineralization1.19128840
69* MP0001177_atelectasis1.19003721
70MP0003385_abnormal_body_wall1.18466374
71MP0002734_abnormal_mechanical_nocicepti1.17351894
72MP0002938_white_spotting1.14515404
73MP0003091_abnormal_cell_migration1.14513416
74MP0001440_abnormal_grooming_behavior1.13329868
75MP0002067_abnormal_sensory_capabilities1.12844455
76MP0002064_seizures1.12008203
77MP0000372_irregular_coat_pigmentation1.11944284
78MP0009745_abnormal_behavioral_response1.11830282
79MP0001501_abnormal_sleep_pattern1.10601649
80MP0003634_abnormal_glial_cell1.09994176
81MP0005666_abnormal_adipose_tissue1.09688560
82MP0006276_abnormal_autonomic_nervous1.08515668
83MP0003938_abnormal_ear_development1.07647648
84MP0001186_pigmentation_phenotype1.06413461
85MP0000427_abnormal_hair_cycle1.06194087
86MP0000163_abnormal_cartilage_morphology1.05247081
87MP0004484_altered_response_of1.04489995
88MP0003635_abnormal_synaptic_transmissio1.03674959
89* MP0002272_abnormal_nervous_system1.02568571
90MP0003279_aneurysm1.02167087
91MP0003011_delayed_dark_adaptation1.01379995
92MP0000013_abnormal_adipose_tissue1.00868806
93MP0005670_abnormal_white_adipose1.00001860
94MP0003959_abnormal_lean_body0.99888301
95MP0003943_abnormal_hepatobiliary_system0.99664031
96MP0002115_abnormal_skeleton_extremities0.99046312
97MP0000762_abnormal_tongue_morphology0.98726667
98MP0002295_abnormal_pulmonary_circulatio0.97934953
99MP0001286_abnormal_eye_development0.97597538
100MP0001661_extended_life_span0.97441318
101MP0002095_abnormal_skin_pigmentation0.96676125
102MP0001879_abnormal_lymphatic_vessel0.96395323
103MP0001968_abnormal_touch/_nociception0.95498660
104MP0003755_abnormal_palate_morphology0.95228620
105MP0003868_abnormal_feces_composition0.94538179
106MP0002233_abnormal_nose_morphology0.94375558
107MP0002102_abnormal_ear_morphology0.94122084
108MP0000604_amyloidosis0.94075735
109MP0002572_abnormal_emotion/affect_behav0.93892834
110MP0005375_adipose_tissue_phenotype0.92899621
111MP0004019_abnormal_vitamin_homeostasis0.92672359
112MP0005508_abnormal_skeleton_morphology0.92557263
113MP0009703_decreased_birth_body0.92344327
114MP0001270_distended_abdomen0.92236248
115MP0002249_abnormal_larynx_morphology0.92236032
116MP0002090_abnormal_vision0.92213566
117MP0000538_abnormal_urinary_bladder0.92100881
118MP0005391_vision/eye_phenotype0.91702820
119MP0003942_abnormal_urinary_system0.90747579
120MP0002735_abnormal_chemical_nociception0.90230544
121MP0005377_hearing/vestibular/ear_phenot0.89251566
122MP0003878_abnormal_ear_physiology0.89251566
123MP0002063_abnormal_learning/memory/cond0.89061743
124MP0002736_abnormal_nociception_after0.88755144
125MP0003566_abnormal_cell_adhesion0.87509917
126MP0005023_abnormal_wound_healing0.87494651
127MP0005193_abnormal_anterior_eye0.86513155
128MP0009379_abnormal_foot_pigmentation0.86323338
129* MP0005388_respiratory_system_phenotype0.86170607
130* MP0002133_abnormal_respiratory_system0.86170607
131MP0001963_abnormal_hearing_physiology0.85771813
132MP0000003_abnormal_adipose_tissue0.85509250
133MP0002136_abnormal_kidney_physiology0.84113426
134MP0008961_abnormal_basal_metabolism0.83713633
135MP0009697_abnormal_copulation0.83535323
136MP0003122_maternal_imprinting0.83464519
137MP0001293_anophthalmia0.83065296
138MP0005636_abnormal_mineral_homeostasis0.82153890
139MP0002109_abnormal_limb_morphology0.82007246
140* MP0003632_abnormal_nervous_system0.80963718
141MP0001485_abnormal_pinna_reflex0.80952577
142MP0005423_abnormal_somatic_nervous0.80118382
143MP0000026_abnormal_inner_ear0.80008696
144MP0002088_abnormal_embryonic_growth/wei0.79866874
145MP0004084_abnormal_cardiac_muscle0.78989528
146MP0002084_abnormal_developmental_patter0.78429272
147MP0003453_abnormal_keratinocyte_physiol0.78119444
148MP0003984_embryonic_growth_retardation0.78051830
149MP0010386_abnormal_urinary_bladder0.77966062
150MP0004185_abnormal_adipocyte_glucose0.76929146
151MP0005395_other_phenotype0.76747497
152MP0002557_abnormal_social/conspecific_i0.76612396
153MP0002116_abnormal_craniofacial_bone0.76126959
154MP0000569_abnormal_digit_pigmentation0.75757085
155MP0000383_abnormal_hair_follicle0.75755431
156MP0002184_abnormal_innervation0.75604345
157MP0005164_abnormal_response_to0.75330171
158MP0004142_abnormal_muscle_tone0.75193775
159MP0004808_abnormal_hematopoietic_stem0.73934975
160MP0002086_abnormal_extraembryonic_tissu0.72561903
161MP0000537_abnormal_urethra_morphology0.70157244
162MP0005647_abnormal_sex_gland0.69890689
163MP0003936_abnormal_reproductive_system0.68995394
164MP0003828_pulmonary_edema0.68403504
165MP0000377_abnormal_hair_follicle0.68379942
166MP0004233_abnormal_muscle_weight0.67283684

Predicted human phenotypes

RankGene SetZ-score
1Metabolic alkalosis (HP:0200114)7.97186114
2Hypokalemic alkalosis (HP:0001949)6.51320642
3Increased circulating renin level (HP:0000848)6.15200573
4Hypomagnesemia (HP:0002917)6.12113076
5Abnormality of chloride homeostasis (HP:0011422)5.39940909
6Polyuria (HP:0000103)5.25878612
7Abnormal urine output (HP:0012590)4.86019204
8Hyperactive renin-angiotensin system (HP:0000841)4.85677283
9Abnormality of magnesium homeostasis (HP:0004921)4.82890407
10Abnormal drinking behavior (HP:0030082)4.54939963
11Polydipsia (HP:0001959)4.54939963
12Abnormality of renal excretion (HP:0011036)4.48227284
13Hyperaldosteronism (HP:0000859)4.41660904
14Tetany (HP:0001281)4.13488190
15Renal salt wasting (HP:0000127)3.96154150
16Papillary thyroid carcinoma (HP:0002895)3.65421525
17Abnormality of renin-angiotensin system (HP:0000847)3.55677451
18Absent frontal sinuses (HP:0002688)3.53114522
19Subacute progressive viral hepatitis (HP:0006572)3.30792288
20Hypokalemia (HP:0002900)3.22021050
21Alkalosis (HP:0001948)3.11034345
22Degeneration of the lateral corticospinal tracts (HP:0002314)3.05052694
23Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.05052694
24Osteolytic defects of the hand bones (HP:0009699)2.93574421
25Osteolytic defects of the phalanges of the hand (HP:0009771)2.93574421
26Aplasia involving bones of the upper limbs (HP:0009823)2.90795658
27Aplasia of the phalanges of the hand (HP:0009802)2.90795658
28Aplasia involving bones of the extremities (HP:0009825)2.90795658
29Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.89032592
30Thyroid carcinoma (HP:0002890)2.72625263
31Abnormality of potassium homeostasis (HP:0011042)2.69222622
32Hypoplasia of the iris (HP:0007676)2.67770162
33Premature rupture of membranes (HP:0001788)2.57755006
34Hypopigmentation of the fundus (HP:0007894)2.57634363
35Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.52229075
36Follicular hyperkeratosis (HP:0007502)2.42751078
37Syringomyelia (HP:0003396)2.35480942
38Spinal cord lesions (HP:0100561)2.35480942
39Abnormality of the corticospinal tract (HP:0002492)2.33857805
40Overgrowth (HP:0001548)2.29713871
41Spondylolisthesis (HP:0003302)2.28942943
42Scanning speech (HP:0002168)2.28799006
43Large earlobe (HP:0009748)2.27386393
44Vertebral arch anomaly (HP:0008438)2.27214135
45Protrusio acetabuli (HP:0003179)2.21462879
46Termporal pattern (HP:0011008)2.20530841
47Insidious onset (HP:0003587)2.20530841
48Neonatal short-limb short stature (HP:0008921)2.18732998
49Abnormality of the middle phalanges of the toes (HP:0010183)2.17867850
50Hypercalciuria (HP:0002150)2.16144606
51Abnormality of the frontal sinuses (HP:0002687)2.14969673
52Proximal tubulopathy (HP:0000114)2.14061269
53Abnormality of the fovea (HP:0000493)2.12478421
54Sensory axonal neuropathy (HP:0003390)2.12111513
55Vascular tortuosity (HP:0004948)2.11776647
56Curly hair (HP:0002212)2.10622669
57Heterotopia (HP:0002282)2.09012639
58Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.05375681
59Stomach cancer (HP:0012126)2.03470907
60Adrenal overactivity (HP:0002717)2.01623227
61Volvulus (HP:0002580)2.00294654
62Generalized hypopigmentation of hair (HP:0011358)1.99395887
63Abnormal ciliary motility (HP:0012262)1.99156793
64Abnormality of sodium homeostasis (HP:0010931)1.98101795
65Abnormality of liposaccharide metabolism (HP:0010968)1.96169020
66Abnormality of glycosphingolipid metabolism (HP:0004343)1.96169020
67Abnormality of glycolipid metabolism (HP:0010969)1.96169020
68Transitional cell carcinoma of the bladder (HP:0006740)1.95679734
69Coronal craniosynostosis (HP:0004440)1.94706909
70Spinal rigidity (HP:0003306)1.93313816
71Cervical subluxation (HP:0003308)1.92916987
72Buphthalmos (HP:0000557)1.92365439
73Hepatoblastoma (HP:0002884)1.91903208
74Bladder carcinoma (HP:0002862)1.91708499
75Bladder neoplasm (HP:0009725)1.91708499
76Arterial tortuosity (HP:0005116)1.91467301
77Abnormal respiratory motile cilium physiology (HP:0012261)1.89414157
78Narrow palate (HP:0000189)1.87388992
79Shallow orbits (HP:0000586)1.84648321
80Freckling (HP:0001480)1.84219384
81Ankle contracture (HP:0006466)1.83141153
82Bilateral sensorineural hearing impairment (HP:0008619)1.82687985
83Macroorchidism (HP:0000053)1.82676318
84Cubitus valgus (HP:0002967)1.82632765
85Epidermoid cyst (HP:0200040)1.79754279
86Abnormality of incisor morphology (HP:0011063)1.78569298
87Onion bulb formation (HP:0003383)1.77434204
88Stage 5 chronic kidney disease (HP:0003774)1.77046180
89Abnormality of the ischium (HP:0003174)1.76862356
90Bifid tongue (HP:0010297)1.74941873
91Ankyloglossia (HP:0010296)1.74816345
92Overlapping toe (HP:0001845)1.74748329
93Choroideremia (HP:0001139)1.74531300
94Abnormal eating behavior (HP:0100738)1.74448481
95Aortic dissection (HP:0002647)1.74076220
96Wide nose (HP:0000445)1.73941074
97Uterine leiomyosarcoma (HP:0002891)1.73934114
98Leiomyosarcoma (HP:0100243)1.73934114
99Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.73203317
100Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.73122631
101Polyphagia (HP:0002591)1.72211138
102Abnormality of the epiphyses of the hand (HP:0005924)1.72034842
103Aortic aneurysm (HP:0004942)1.71949380
104Bell-shaped thorax (HP:0001591)1.69503971
105Broad metatarsal (HP:0001783)1.68389632
106Infantile muscular hypotonia (HP:0008947)1.68194321
107Abnormality of the nasal septum (HP:0000419)1.67416306
108Abnormality of the phalanges of the 2nd finger (HP:0009541)1.65166025
109Hypoplastic labia majora (HP:0000059)1.64056976
110Drooling (HP:0002307)1.63746519
111Excessive salivation (HP:0003781)1.63746519
112Abnormality of the renal medulla (HP:0100957)1.63618379
113Fair hair (HP:0002286)1.62424253
114Fibular hypoplasia (HP:0003038)1.61289624
115Intellectual disability, moderate (HP:0002342)1.61231984
116Truncal obesity (HP:0001956)1.61223625
117Abnormality of the 2nd finger (HP:0004100)1.61068510
118Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.61019341
119Viral hepatitis (HP:0006562)1.60634535
120Deep philtrum (HP:0002002)1.60470327
121Segmental peripheral demyelination/remyelination (HP:0003481)1.59707382
122Pulmonic stenosis (HP:0001642)1.59103963
123Abnormality of chromosome stability (HP:0003220)1.58540987
124Neurofibrillary tangles (HP:0002185)1.58166097
125Abnormality of the astrocytes (HP:0100707)1.57516583
126Astrocytoma (HP:0009592)1.57516583
127Mitral stenosis (HP:0001718)1.57103554
128Tubular atrophy (HP:0000092)1.57046033
129Acute myeloid leukemia (HP:0004808)1.56896797
130Menstrual irregularities (HP:0000858)1.56758412
131Atrophic scars (HP:0001075)1.56383025
132Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.55493234
133Knee flexion contracture (HP:0006380)1.54275210
134Abnormal auditory evoked potentials (HP:0006958)1.54088282
135Hyperventilation (HP:0002883)1.53872255
136Myocardial infarction (HP:0001658)1.53319488
137Abnormality of dentin (HP:0010299)1.53293994
138Wormian bones (HP:0002645)1.52996434
139Aplasia/Hypoplasia of the fibula (HP:0006492)1.52180040
140Short hallux (HP:0010109)1.51891468
141Tetraparesis (HP:0002273)1.51753451
142Autoamputation (HP:0001218)1.51713359
143Synostosis involving the elbow (HP:0003938)1.51067843
144Humeroradial synostosis (HP:0003041)1.51067843
145Nephrocalcinosis (HP:0000121)1.48753591
146Relative macrocephaly (HP:0004482)1.48292227
147Submucous cleft hard palate (HP:0000176)1.48256122
148Action tremor (HP:0002345)1.47737930
149Limited hip movement (HP:0008800)1.46398077
150Renal tubular acidosis (HP:0001947)1.46389650
151Tubulointerstitial fibrosis (HP:0005576)1.46176931
152Stridor (HP:0010307)1.45320888
153Wide anterior fontanel (HP:0000260)1.44982873
154Corneal dystrophy (HP:0001131)1.43660718
155Blue irides (HP:0000635)1.43600642
156Parakeratosis (HP:0001036)1.42264820
157Abnormality of the fibula (HP:0002991)1.42249599
158Broad ribs (HP:0000885)1.41473321
159Nonprogressive disorder (HP:0003680)1.41460124
160Dynein arm defect of respiratory motile cilia (HP:0012255)1.41231110
161Absent/shortened dynein arms (HP:0200106)1.41231110
162Generalized muscle weakness (HP:0003324)1.40486087
163Focal motor seizures (HP:0011153)1.40350797
164Progressive cerebellar ataxia (HP:0002073)1.39761173
165Facial shape deformation (HP:0011334)1.39585584
166Potter facies (HP:0002009)1.39585584
167Broad-based gait (HP:0002136)1.39067914
168Epiphyseal dysplasia (HP:0002656)1.38821073

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK35.45896774
2OXSR15.18757664
3STK394.42501054
4WNK44.02542312
5CASK3.66891039
6ACVR1B2.36160747
7TIE12.35183362
8BRD42.07152610
9STK38L2.03205365
10SGK4941.98594561
11SGK2231.98594561
12WNK11.93801437
13STK241.89901122
14WEE11.77230772
15CAMK1G1.76733260
16EPHB11.66129552
17MST41.65479629
18DDR21.65407384
19CAMK1D1.63033376
20ERBB31.56730223
21EIF2AK31.56249785
22BRSK21.55351708
23NEK91.55309115
24LATS11.50165073
25MAPKAPK51.45955922
26MELK1.45420569
27SIK11.43775534
28FER1.41134856
29SGK21.40983208
30PNCK1.39886281
31MUSK1.32800948
32BCR1.29729240
33AKT31.27742929
34MAP3K101.26864132
35PKN21.26176112
36FGFR21.25235484
37PKN11.16419476
38NTRK11.14682213
39PDK21.08081302
40FRK1.05431806
41NEK61.04412755
42TNIK1.04328349
43CDK61.03768053
44PRKCE1.01969097
45PLK21.00952739
46ZAK1.00092752
47EPHA31.00091085
48ROCK20.99916170
49SGK30.95578368
50SCYL20.95558015
51INSRR0.95316435
52NTRK20.94867980
53FGFR30.91892022
54BMPR1B0.90877571
55MKNK20.89775593
56TGFBR10.89319281
57MAP3K20.88747259
58MAPK130.88450216
59CDK120.84092632
60PAK30.83777882
61PIK3CA0.83356414
62MARK10.82326817
63FLT30.81932146
64GSK3A0.81045175
65MET0.80214607
66NTRK30.79787790
67SGK10.79450032
68KSR10.79428895
69CSNK1A1L0.78198937
70MAPK150.75362924
71CAMK2B0.74950120
72BMX0.74042468
73PBK0.73845667
74MKNK10.73202419
75MAP2K70.72067505
76ERBB40.71509984
77MST1R0.71203544
78TTK0.70574094
79JAK10.70402949
80EPHB20.69495496
81TSSK60.68921813
82PAK20.67776316
83ROCK10.67598831
84FGR0.66901102
85GRK10.65489485
86CSNK1G10.63916023
87MAP3K40.63222454
88CAMK2A0.62890219
89PAK60.61070782
90TRPM70.60574978
91NUAK10.60294298
92INSR0.59642383
93EPHA40.58497398
94MARK20.58455170
95PRKD20.54849090
96PRKCH0.54835178
97ICK0.54825722
98LMTK20.54492946
99TRIM280.54238228
100PRKAA20.54096274
101CAMK2D0.53169372
102CDK90.53052530
103RET0.52933522
104MTOR0.52239578
105EEF2K0.51602770
106CDK50.51417165
107LATS20.50268627
108BMPR20.49127695
109ATM0.48697594
110STK30.48568342
111PTK2B0.48404518
112PHKG10.47869645
113PHKG20.47869645
114PLK30.47355966
115NLK0.46395994
116MAP3K140.44901711
117UHMK10.44699260
118PDGFRB0.44039064
119PDGFRA0.43999242
120IRAK10.41357001
121FGFR10.40851169
122ADRBK10.40734770
123PDK30.40488813
124PDK40.40488813
125DYRK1A0.40342767
126CAMKK20.40175657
127PRKCQ0.40120810
128TAF10.38547254
129PLK40.37814605
130CSNK1G20.37641449
131IGF1R0.36980900
132IRAK20.36266369
133TTN0.35211004
134STK380.35137104
135SRC0.34881338
136MARK30.34298491
137MAP3K60.34020521
138YES10.33774561
139EGFR0.30043703
140PTK20.30043301
141BRAF0.27855520
142RAF10.27072193
143MAPK100.27068855
144PRKAA10.26643803
145CDK80.26491500
146DMPK0.25926332
147ABL10.24691232

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.40277393
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.34122704
3Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.03091283
4ECM-receptor interaction_Homo sapiens_hsa045121.96793331
5Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.95674258
6Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.93555591
7Fatty acid elongation_Homo sapiens_hsa000621.93537338
8Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.90991760
9Collecting duct acid secretion_Homo sapiens_hsa049661.84615648
10Endometrial cancer_Homo sapiens_hsa052131.83015126
11Gastric acid secretion_Homo sapiens_hsa049711.76093962
12Thyroid cancer_Homo sapiens_hsa052161.74787001
13Steroid biosynthesis_Homo sapiens_hsa001001.71250821
14Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.70941846
15Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.58031250
16Fatty acid biosynthesis_Homo sapiens_hsa000611.55183303
17Nicotine addiction_Homo sapiens_hsa050331.53988628
18Protein digestion and absorption_Homo sapiens_hsa049741.53843710
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.52905565
20Colorectal cancer_Homo sapiens_hsa052101.50909325
21Pancreatic cancer_Homo sapiens_hsa052121.48225910
22Inositol phosphate metabolism_Homo sapiens_hsa005621.48185876
23Non-homologous end-joining_Homo sapiens_hsa034501.46816794
24Lysine degradation_Homo sapiens_hsa003101.43412781
25Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.42352087
26Mineral absorption_Homo sapiens_hsa049781.41012246
27Sulfur metabolism_Homo sapiens_hsa009201.38632999
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.36312963
29Rheumatoid arthritis_Homo sapiens_hsa053231.35372553
30Salivary secretion_Homo sapiens_hsa049701.31188363
31Sphingolipid metabolism_Homo sapiens_hsa006001.30337842
32Axon guidance_Homo sapiens_hsa043601.29923464
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.29786131
34Non-small cell lung cancer_Homo sapiens_hsa052231.28756730
35Thyroid hormone signaling pathway_Homo sapiens_hsa049191.28589145
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.25132786
37Lysosome_Homo sapiens_hsa041421.22143112
38GABAergic synapse_Homo sapiens_hsa047271.21226330
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.19181055
40Chronic myeloid leukemia_Homo sapiens_hsa052201.18592158
41Propanoate metabolism_Homo sapiens_hsa006401.17502256
42Renin secretion_Homo sapiens_hsa049241.17377906
43Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.15918843
44Focal adhesion_Homo sapiens_hsa045101.15294779
45Vibrio cholerae infection_Homo sapiens_hsa051101.15279055
46Butanoate metabolism_Homo sapiens_hsa006501.13371548
47Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.12634315
48Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.12065216
49Ether lipid metabolism_Homo sapiens_hsa005651.08263402
50FoxO signaling pathway_Homo sapiens_hsa040681.08019978
51Glutamatergic synapse_Homo sapiens_hsa047241.07803461
52Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.07692984
53Morphine addiction_Homo sapiens_hsa050321.07260466
54mTOR signaling pathway_Homo sapiens_hsa041501.03062556
55Other glycan degradation_Homo sapiens_hsa005111.02230713
56Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.02082782
57Serotonergic synapse_Homo sapiens_hsa047261.01955194
58Hedgehog signaling pathway_Homo sapiens_hsa043400.98773098
59Long-term depression_Homo sapiens_hsa047300.98216761
60Thyroid hormone synthesis_Homo sapiens_hsa049180.98120687
61Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97578339
62Central carbon metabolism in cancer_Homo sapiens_hsa052300.97003343
63Taste transduction_Homo sapiens_hsa047420.96163656
64Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.95450786
65Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.93940852
66Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.93557370
67Basal cell carcinoma_Homo sapiens_hsa052170.93298593
68Cell cycle_Homo sapiens_hsa041100.93272499
69Prolactin signaling pathway_Homo sapiens_hsa049170.92258454
70Prostate cancer_Homo sapiens_hsa052150.91399571
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.86857643
72Cocaine addiction_Homo sapiens_hsa050300.86400894
73Melanogenesis_Homo sapiens_hsa049160.85678616
74Synaptic vesicle cycle_Homo sapiens_hsa047210.84809734
75Circadian entrainment_Homo sapiens_hsa047130.83753698
76Tight junction_Homo sapiens_hsa045300.83591214
77Ras signaling pathway_Homo sapiens_hsa040140.83210016
78Hippo signaling pathway_Homo sapiens_hsa043900.83194922
79Fatty acid metabolism_Homo sapiens_hsa012120.83028271
80Melanoma_Homo sapiens_hsa052180.82724912
81Oxidative phosphorylation_Homo sapiens_hsa001900.81507482
82Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.80677939
83ErbB signaling pathway_Homo sapiens_hsa040120.80114532
84Vitamin digestion and absorption_Homo sapiens_hsa049770.79784121
85HIF-1 signaling pathway_Homo sapiens_hsa040660.79759637
86PI3K-Akt signaling pathway_Homo sapiens_hsa041510.79108666
87Ovarian steroidogenesis_Homo sapiens_hsa049130.79075321
88Gap junction_Homo sapiens_hsa045400.78399713
89p53 signaling pathway_Homo sapiens_hsa041150.76739419
90Bile secretion_Homo sapiens_hsa049760.75851670
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75799249
92Primary bile acid biosynthesis_Homo sapiens_hsa001200.75653419
93Proteoglycans in cancer_Homo sapiens_hsa052050.75335001
94Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.74989701
95PPAR signaling pathway_Homo sapiens_hsa033200.74536345
96cAMP signaling pathway_Homo sapiens_hsa040240.74525888
97Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.74028727
98Dilated cardiomyopathy_Homo sapiens_hsa054140.73843716
99Autoimmune thyroid disease_Homo sapiens_hsa053200.73442179
100Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.73095004
101TGF-beta signaling pathway_Homo sapiens_hsa043500.72812162
102Renin-angiotensin system_Homo sapiens_hsa046140.71353149
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70209703
104Phagosome_Homo sapiens_hsa041450.69733524
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.69636624
106Wnt signaling pathway_Homo sapiens_hsa043100.69579585
107Glioma_Homo sapiens_hsa052140.66517411
108Rap1 signaling pathway_Homo sapiens_hsa040150.66493450
109Amoebiasis_Homo sapiens_hsa051460.64230390
110Renal cell carcinoma_Homo sapiens_hsa052110.63611448
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.62848124
112Small cell lung cancer_Homo sapiens_hsa052220.62736001
113Type II diabetes mellitus_Homo sapiens_hsa049300.62720943
114Bladder cancer_Homo sapiens_hsa052190.61795742
115Toxoplasmosis_Homo sapiens_hsa051450.60986096
116Circadian rhythm_Homo sapiens_hsa047100.59711586
117Choline metabolism in cancer_Homo sapiens_hsa052310.58944840
118Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.57957543
119Amphetamine addiction_Homo sapiens_hsa050310.57829977
120Adherens junction_Homo sapiens_hsa045200.57325232
121Dorso-ventral axis formation_Homo sapiens_hsa043200.56989418
122Fanconi anemia pathway_Homo sapiens_hsa034600.56915012
123AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55699664
124Cholinergic synapse_Homo sapiens_hsa047250.55457034
125Pathways in cancer_Homo sapiens_hsa052000.55205415
126Dopaminergic synapse_Homo sapiens_hsa047280.54831115
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54575788
128Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54435470
129Vascular smooth muscle contraction_Homo sapiens_hsa042700.54402204
130Hepatitis B_Homo sapiens_hsa051610.54220778
131TNF signaling pathway_Homo sapiens_hsa046680.53865093
132Phospholipase D signaling pathway_Homo sapiens_hsa040720.53852547
133Vitamin B6 metabolism_Homo sapiens_hsa007500.53315026
134Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53279426
135Selenocompound metabolism_Homo sapiens_hsa004500.52516774
136Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51173181
137Sphingolipid signaling pathway_Homo sapiens_hsa040710.50995330
138Viral carcinogenesis_Homo sapiens_hsa052030.50557299
139MicroRNAs in cancer_Homo sapiens_hsa052060.50238507
140Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50111218
141Systemic lupus erythematosus_Homo sapiens_hsa053220.49440919
142Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48616047
143Calcium signaling pathway_Homo sapiens_hsa040200.47915117
144Long-term potentiation_Homo sapiens_hsa047200.46667964
145Estrogen signaling pathway_Homo sapiens_hsa049150.46635974
146Jak-STAT signaling pathway_Homo sapiens_hsa046300.45789454
147Alcoholism_Homo sapiens_hsa050340.42268176
148Insulin signaling pathway_Homo sapiens_hsa049100.41868825
149Apoptosis_Homo sapiens_hsa042100.38130170
150N-Glycan biosynthesis_Homo sapiens_hsa005100.37985657

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