SLC5A6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1purine nucleobase biosynthetic process (GO:0009113)8.43349519
2nucleobase biosynthetic process (GO:0046112)7.32000681
3ribosome assembly (GO:0042255)6.17453363
4folic acid metabolic process (GO:0046655)6.11723229
5GMP metabolic process (GO:0046037)5.96963130
6regulation of attachment of spindle microtubules to kinetochore (GO:0051988)5.77704195
7mitotic metaphase plate congression (GO:0007080)5.72562380
8regulation of spindle organization (GO:0090224)5.72253626
9folic acid transport (GO:0015884)5.68036635
10ribosome biogenesis (GO:0042254)5.33310420
11lung-associated mesenchyme development (GO:0060484)5.00332202
12proline biosynthetic process (GO:0006561)4.84041831
13DNA unwinding involved in DNA replication (GO:0006268)4.75222241
14DNA replication checkpoint (GO:0000076)4.66718224
15NADH metabolic process (GO:0006734)4.56301462
16CDP-diacylglycerol metabolic process (GO:0046341)4.56171061
17regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.56078523
18regulation of mitotic spindle organization (GO:0060236)4.49847018
19DNA strand elongation involved in DNA replication (GO:0006271)4.49794887
20transcription elongation from RNA polymerase III promoter (GO:0006385)4.49037577
21termination of RNA polymerase III transcription (GO:0006386)4.49037577
22S-adenosylmethionine metabolic process (GO:0046500)4.40573330
23nuclear pore complex assembly (GO:0051292)4.37267830
24positive regulation of chromosome segregation (GO:0051984)4.37113393
25DNA strand elongation (GO:0022616)4.36669370
26rRNA modification (GO:0000154)4.35177957
27autophagic vacuole assembly (GO:0000045)4.33642162
28glycine metabolic process (GO:0006544)4.23748584
29blastocyst development (GO:0001824)4.21236800
30transcription elongation from RNA polymerase I promoter (GO:0006362)4.20975929
31metaphase plate congression (GO:0051310)4.20185931
32termination of RNA polymerase I transcription (GO:0006363)4.13403457
33regulation of translational fidelity (GO:0006450)4.08683696
34regulation of G0 to G1 transition (GO:0070316)4.01470136
35transcription from RNA polymerase I promoter (GO:0006360)3.95836817
36proline metabolic process (GO:0006560)3.94662049
37serine family amino acid catabolic process (GO:0009071)3.94115299
38IMP biosynthetic process (GO:0006188)3.92315138
39histone-serine phosphorylation (GO:0035404)3.90025475
40peptidyl-arginine omega-N-methylation (GO:0035247)3.89283395
41proteasome assembly (GO:0043248)3.89160378
42establishment of integrated proviral latency (GO:0075713)3.79514676
43regulation of translation in response to stress (GO:0043555)3.79276982
447-methylguanosine mRNA capping (GO:0006370)3.77788883
45mitotic chromosome condensation (GO:0007076)3.76105188
46amino acid salvage (GO:0043102)3.75104492
47L-methionine salvage (GO:0071267)3.75104492
48L-methionine biosynthetic process (GO:0071265)3.75104492
49transcription initiation from RNA polymerase I promoter (GO:0006361)3.73302508
50nuclear pore organization (GO:0006999)3.72769763
51guanosine-containing compound biosynthetic process (GO:1901070)3.70811285
52spindle checkpoint (GO:0031577)3.70728660
53telomere maintenance via semi-conservative replication (GO:0032201)3.70229882
54intestinal epithelial cell development (GO:0060576)3.69716578
55histone arginine methylation (GO:0034969)3.68891625
56anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.68448959
57mitotic spindle checkpoint (GO:0071174)3.65541658
58RNA capping (GO:0036260)3.63211690
597-methylguanosine RNA capping (GO:0009452)3.63211690
60protein complex localization (GO:0031503)3.60536029
61ribonucleoprotein complex biogenesis (GO:0022613)3.59553064
62regulation of chromosome segregation (GO:0051983)3.58862175
63rRNA methylation (GO:0031167)3.53117393
64maturation of 5.8S rRNA (GO:0000460)3.52332414
65CDP-diacylglycerol biosynthetic process (GO:0016024)3.51355372
66rRNA processing (GO:0006364)3.50408592
67formation of translation preinitiation complex (GO:0001731)3.48437450
68regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.47716401
69positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.45552031
70* vitamin transmembrane transport (GO:0035461)3.43905945
71IMP metabolic process (GO:0046040)3.43491315
72protein localization to chromosome, centromeric region (GO:0071459)3.43450055
73spliceosomal snRNP assembly (GO:0000387)3.42036565
74rRNA metabolic process (GO:0016072)3.40663358
75negative regulation of chromosome segregation (GO:0051985)3.40315750
76mitotic nuclear envelope disassembly (GO:0007077)3.39828523
77mitotic spindle assembly checkpoint (GO:0007094)3.37563724
78folic acid-containing compound biosynthetic process (GO:0009396)3.37514350
79pyrimidine-containing compound transmembrane transport (GO:0072531)3.36722437
80maturation of SSU-rRNA (GO:0030490)3.36187023
81mitotic sister chromatid segregation (GO:0000070)3.36022449
82protein localization to kinetochore (GO:0034501)3.35299909
83negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.32928490
84negative regulation of sister chromatid segregation (GO:0033046)3.32928490
85negative regulation of mitotic sister chromatid separation (GO:2000816)3.32928490
86negative regulation of mitotic sister chromatid segregation (GO:0033048)3.32928490
87regulation of exit from mitosis (GO:0007096)3.30199949
88methionine biosynthetic process (GO:0009086)3.29589341
89methionine metabolic process (GO:0006555)3.27252572
90spindle assembly checkpoint (GO:0071173)3.26811560
91DNA-templated transcription, elongation (GO:0006354)3.22903423
92negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.22481638
93Golgi transport vesicle coating (GO:0048200)3.21246416
94COPI coating of Golgi vesicle (GO:0048205)3.21246416
95positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.18909276
96negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.18102592
97L-serine metabolic process (GO:0006563)3.18101267
98nuclear envelope disassembly (GO:0051081)3.18032908
99membrane disassembly (GO:0030397)3.18032908
100peptidyl-arginine methylation (GO:0018216)3.16386777
101peptidyl-arginine N-methylation (GO:0035246)3.16386777
102regulation of mitotic metaphase/anaphase transition (GO:0030071)3.16101381
103negative regulation of fibroblast apoptotic process (GO:2000270)3.15544770
104heterochromatin organization (GO:0070828)3.13930212
105nuclear envelope organization (GO:0006998)3.12394470
106negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.12136044
107DNA duplex unwinding (GO:0032508)3.11668883
108meiosis I (GO:0007127)3.11032054
109DNA deamination (GO:0045006)3.09698792
110pore complex assembly (GO:0046931)3.09663695
111peptidyl-threonine dephosphorylation (GO:0035970)3.09173630
112regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.08411248
113transcription elongation from RNA polymerase II promoter (GO:0006368)3.07351395
114sister chromatid segregation (GO:0000819)3.07108098
115transcription from mitochondrial promoter (GO:0006390)3.06604354
116L-alpha-amino acid transmembrane transport (GO:1902475)3.04855308
117inner cell mass cell proliferation (GO:0001833)3.04067010
118serine family amino acid metabolic process (GO:0009069)3.02584908
119cellular protein complex localization (GO:0034629)3.02484516
120neurotransmitter catabolic process (GO:0042135)3.01177502
121monoubiquitinated protein deubiquitination (GO:0035520)3.01059740
122establishment of chromosome localization (GO:0051303)3.01012571
123telomere maintenance via recombination (GO:0000722)2.98432267
124sulfur amino acid biosynthetic process (GO:0000097)2.98430448
125spliceosomal tri-snRNP complex assembly (GO:0000244)2.98366919
126DNA geometric change (GO:0032392)2.98046489
127mitotic G1 DNA damage checkpoint (GO:0031571)2.97148565
128positive regulation of ligase activity (GO:0051351)2.97137404
129regulation of mammary gland epithelial cell proliferation (GO:0033599)2.95745236
130serine family amino acid biosynthetic process (GO:0009070)2.95655006
131positive regulation of viral transcription (GO:0050434)2.94803109
132DNA replication initiation (GO:0006270)2.94414609
133positive regulation of autophagy (GO:0010508)2.94303504
134UDP-N-acetylglucosamine metabolic process (GO:0006047)2.93335322
135tetrahydrofolate metabolic process (GO:0046653)2.88034981
136mitotic sister chromatid cohesion (GO:0007064)2.86782883
137regulation of translational termination (GO:0006449)2.85927230
138establishment of viral latency (GO:0019043)2.85923511
139mitotic recombination (GO:0006312)2.80525271
140negative regulation of mRNA processing (GO:0050686)2.78382559
141negative regulation of mRNA metabolic process (GO:1903312)2.74648493
142rRNA transcription (GO:0009303)2.74635482
143NADPH regeneration (GO:0006740)2.74627455
144tRNA aminoacylation for protein translation (GO:0006418)2.74337841
145DNA topological change (GO:0006265)2.73827085
146L-phenylalanine metabolic process (GO:0006558)2.69569892
147erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.69569892
148regulation of mitochondrial translation (GO:0070129)2.69371187
149DNA conformation change (GO:0071103)2.67829816
150nucleobase-containing small molecule interconversion (GO:0015949)2.65325463
151DNA replication-dependent nucleosome organization (GO:0034723)2.64284666
152DNA replication-dependent nucleosome assembly (GO:0006335)2.64284666
153protein export from nucleus (GO:0006611)2.62674397
154amino acid activation (GO:0043038)2.62248001
155tRNA aminoacylation (GO:0043039)2.62248001
156pre-miRNA processing (GO:0031054)2.61602727
157pentose-phosphate shunt (GO:0006098)2.59543763
158telomere maintenance via telomere lengthening (GO:0010833)2.57507670
159chromosome condensation (GO:0030261)2.56716868
160non-recombinational repair (GO:0000726)2.56216657
161double-strand break repair via nonhomologous end joining (GO:0006303)2.56216657
162maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.52816427
163base-excision repair (GO:0006284)2.51429343
164oxaloacetate metabolic process (GO:0006107)2.50185058
165protein-DNA complex disassembly (GO:0032986)2.49564764
166nucleosome disassembly (GO:0006337)2.49564764
167regulation of transcription from RNA polymerase I promoter (GO:0006356)2.49170736
168protein maturation by protein folding (GO:0022417)2.49116622

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.36123414
2E2F7_22180533_ChIP-Seq_HELA_Human5.26923200
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.90406239
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.75935740
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.75234519
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.68517252
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.54279995
8* CREB1_15753290_ChIP-ChIP_HEK293T_Human3.39238768
9* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.38251114
10MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.08437585
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.96870062
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.94027248
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.88265440
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.84970317
15AR_21909140_ChIP-Seq_LNCAP_Human2.84043233
16* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.81211239
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.62162721
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.53515978
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.35030092
20VDR_23849224_ChIP-Seq_CD4+_Human2.33146947
21ZNF263_19887448_ChIP-Seq_K562_Human2.32607129
22NANOG_18555785_ChIP-Seq_MESCs_Mouse2.22793216
23GABP_19822575_ChIP-Seq_HepG2_Human2.14786897
24* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.14092241
25POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.09264494
26XRN2_22483619_ChIP-Seq_HELA_Human2.06846549
27ESR1_15608294_ChIP-ChIP_MCF-7_Human1.97697850
28MYCN_18555785_ChIP-Seq_MESCs_Mouse1.96794557
29E2F1_18555785_ChIP-Seq_MESCs_Mouse1.91025144
30NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.87508361
31* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.86578510
32YY1_21170310_ChIP-Seq_MESCs_Mouse1.84017554
33ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.82991661
34FOXP3_21729870_ChIP-Seq_TREG_Human1.81706865
35KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.81591141
36CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.79672814
37KDM5A_27292631_Chip-Seq_BREAST_Human1.77460906
38* PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.74069056
39ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.72147371
40DCP1A_22483619_ChIP-Seq_HELA_Human1.71339357
41THAP11_20581084_ChIP-Seq_MESCs_Mouse1.69422997
42POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.68182045
43* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.53500489
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.53388378
45HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.45303628
46TTF2_22483619_ChIP-Seq_HELA_Human1.45246557
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.42115177
48FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.41632514
49STAT3_1855785_ChIP-Seq_MESCs_Mouse1.40979274
50* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40234339
51* E2F1_21310950_ChIP-Seq_MCF-7_Human1.37907427
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.35613323
53SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.31799594
54PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.30961016
55ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29318517
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29174349
57NOTCH1_21737748_ChIP-Seq_TLL_Human1.29144725
58SRF_21415370_ChIP-Seq_HL-1_Mouse1.28928753
59CIITA_25753668_ChIP-Seq_RAJI_Human1.28558651
60* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.28072959
61PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.27261354
62RACK7_27058665_Chip-Seq_MCF-7_Human1.27257534
63* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.23415736
64NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.21705610
65CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.19745667
66ELK1_22589737_ChIP-Seq_MCF10A_Human1.18676131
67SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.17284854
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16808309
69KAP1_22055183_ChIP-Seq_ESCs_Mouse1.16507705
70DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15535497
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.14381608
72HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.13578810
73NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.12559928
74NANOG_21062744_ChIP-ChIP_HESCs_Human1.12409731
75SALL1_21062744_ChIP-ChIP_HESCs_Human1.12356467
76PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10743028
77* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10307196
78CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09519220
79* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.08711697
80HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.03821259
81TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.02853295
82NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.02092235
83HIF1A_21447827_ChIP-Seq_MCF-7_Human1.01935514
84ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01093413
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01017207
86NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.00651691
87* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.00341320
88LXR_22292898_ChIP-Seq_THP-1_Human1.00066181
89E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99377202
90ZFP281_18757296_ChIP-ChIP_E14_Mouse0.97418316
91CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.97157024
92POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97099495
93KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95858126
94KAP1_27257070_Chip-Seq_ESCs_Mouse0.95207199
95TP63_19390658_ChIP-ChIP_HaCaT_Human0.94619029
96TET1_21451524_ChIP-Seq_MESCs_Mouse0.93895192
97SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93576389
98TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.93086575
99POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.92846671
100VDR_21846776_ChIP-Seq_THP-1_Human0.92577434
101CHD1_26751641_Chip-Seq_LNCaP_Human0.92537753
102SOX2_18555785_ChIP-Seq_MESCs_Mouse0.92183664
103EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.92024762
104CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90910695
105SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.90023312
106SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.89562158
107ELK1_19687146_ChIP-ChIP_HELA_Human0.89456045
108TBX5_21415370_ChIP-Seq_HL-1_Mouse0.89122191
109FOXP1_21924763_ChIP-Seq_HESCs_Human0.88815530
110SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88062477
111PPARA_22158963_ChIP-Seq_LIVER_Mouse0.88046129
112* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86985133
113NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.86907565
114OCT4_18692474_ChIP-Seq_MEFs_Mouse0.86063499
115SOX2_18692474_ChIP-Seq_MEFs_Mouse0.85343907
116MYC_22102868_ChIP-Seq_BL_Human0.81906366
117HOXB4_20404135_ChIP-ChIP_EML_Mouse0.81172856
118CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.80760010
119YY1_22570637_ChIP-Seq_MALME-3M_Human0.80737901
120CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.80696723
121TFEB_21752829_ChIP-Seq_HELA_Human0.80355480
122CLOCK_20551151_ChIP-Seq_293T_Human0.78651914
123SOX17_20123909_ChIP-Seq_XEN_Mouse0.78106356
124TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.77930197
125EGR1_19374776_ChIP-ChIP_THP-1_Human0.77755728

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.50056674
2MP0003718_maternal_effect5.10170436
3MP0003111_abnormal_nucleus_morphology4.79763627
4MP0009840_abnormal_foam_cell4.44994400
5MP0008260_abnormal_autophagy4.29201074
6MP0004957_abnormal_blastocyst_morpholog3.67548070
7MP0003878_abnormal_ear_physiology3.49245872
8MP0005377_hearing/vestibular/ear_phenot3.49245872
9MP0010094_abnormal_chromosome_stability3.44239017
10MP0003077_abnormal_cell_cycle3.21372064
11MP0003123_paternal_imprinting2.86720758
12MP0003786_premature_aging2.57200365
13MP0001661_extended_life_span2.48891863
14MP0003941_abnormal_skin_development2.48075450
15MP0000566_synostosis2.38770866
16MP0005451_abnormal_body_composition2.36606642
17MP0008058_abnormal_DNA_repair2.33448398
18MP0001730_embryonic_growth_arrest2.29676980
19MP0005076_abnormal_cell_differentiation2.29455239
20MP0002254_reproductive_system_inflammat2.18601648
21MP0003705_abnormal_hypodermis_morpholog2.13820173
22MP0008057_abnormal_DNA_replication2.10258909
23MP0008932_abnormal_embryonic_tissue2.04963789
24MP0003890_abnormal_embryonic-extraembry1.98512911
25MP0001672_abnormal_embryogenesis/_devel1.89548847
26MP0005380_embryogenesis_phenotype1.89548847
27MP0002796_impaired_skin_barrier1.85624452
28MP0005395_other_phenotype1.82924830
29MP0001542_abnormal_bone_strength1.81159396
30MP0000350_abnormal_cell_proliferation1.79100093
31MP0004233_abnormal_muscle_weight1.78971793
32MP0003221_abnormal_cardiomyocyte_apopto1.76907442
33MP0010307_abnormal_tumor_latency1.72309775
34MP0004185_abnormal_adipocyte_glucose1.67813435
35MP0003984_embryonic_growth_retardation1.65140780
36MP0004019_abnormal_vitamin_homeostasis1.64309203
37MP0010030_abnormal_orbit_morphology1.63431956
38MP0010352_gastrointestinal_tract_polyps1.62768949
39MP0002088_abnormal_embryonic_growth/wei1.61948895
40MP0008007_abnormal_cellular_replicative1.60298279
41MP0002089_abnormal_postnatal_growth/wei1.59897721
42MP0003938_abnormal_ear_development1.57061682
43MP0004885_abnormal_endolymph1.53600514
44MP0000750_abnormal_muscle_regeneration1.51051422
45MP0008877_abnormal_DNA_methylation1.48542330
46MP0009333_abnormal_splenocyte_physiolog1.48359501
47MP0002080_prenatal_lethality1.46796445
48MP0005501_abnormal_skin_physiology1.44623178
49MP0010234_abnormal_vibrissa_follicle1.41289415
50MP0001697_abnormal_embryo_size1.40639862
51MP0001756_abnormal_urination1.40552346
52MP0005332_abnormal_amino_acid1.39711098
53MP0009697_abnormal_copulation1.38162898
54MP0003567_abnormal_fetal_cardiomyocyte1.38058073
55MP0000537_abnormal_urethra_morphology1.34325406
56MP0001849_ear_inflammation1.33245483
57MP0003566_abnormal_cell_adhesion1.24950425
58MP0009672_abnormal_birth_weight1.24498673
59MP0005408_hypopigmentation1.23675607
60MP0002098_abnormal_vibrissa_morphology1.23606945
61MP0002396_abnormal_hematopoietic_system1.20832379
62MP0001346_abnormal_lacrimal_gland1.19847669
63MP0000747_muscle_weakness1.19721712
64MP0001666_abnormal_nutrient_absorption1.19379064
65MP0005058_abnormal_lysosome_morphology1.19053743
66MP0002697_abnormal_eye_size1.17602641
67MP0003879_abnormal_hair_cell1.13251045
68MP0002938_white_spotting1.12353899
69MP0005360_urolithiasis1.11843817
70MP0002210_abnormal_sex_determination1.10982400
71MP0005365_abnormal_bile_salt1.10825578
72MP0001764_abnormal_homeostasis1.10292122
73MP0001881_abnormal_mammary_gland1.09878149
74MP0003136_yellow_coat_color1.06501221
75MP0003656_abnormal_erythrocyte_physiolo1.04425051
76MP0003942_abnormal_urinary_system1.03416014
77MP0002111_abnormal_tail_morphology1.02298636
78MP0002086_abnormal_extraembryonic_tissu1.02295739
79MP0002085_abnormal_embryonic_tissue1.01409063
80MP0003315_abnormal_perineum_morphology1.01281186
81MP0003122_maternal_imprinting1.00377024
82MP0000579_abnormal_nail_morphology0.99558002
83MP0001545_abnormal_hematopoietic_system0.98836932
84MP0005397_hematopoietic_system_phenotyp0.98836932
85MP0001145_abnormal_male_reproductive0.98758743
86MP0005666_abnormal_adipose_tissue0.96814824
87MP0005670_abnormal_white_adipose0.95507676
88MP0001915_intracranial_hemorrhage0.95394346
89MP0000358_abnormal_cell_content/0.94224067
90MP0002132_abnormal_respiratory_system0.93184901
91MP0004084_abnormal_cardiac_muscle0.92524019
92MP0006035_abnormal_mitochondrial_morpho0.91433258
93MP0001929_abnormal_gametogenesis0.91344460
94MP0003806_abnormal_nucleotide_metabolis0.90644158
95MP0003699_abnormal_female_reproductive0.89924802
96MP0000313_abnormal_cell_death0.89824608
97MP0000377_abnormal_hair_follicle0.88927135
98MP0000653_abnormal_sex_gland0.88488567
99MP0006138_congestive_heart_failure0.87365933
100MP0005621_abnormal_cell_physiology0.87200290
101MP0000678_abnormal_parathyroid_gland0.86825894
102MP0003115_abnormal_respiratory_system0.86775009
103MP0002084_abnormal_developmental_patter0.86147448
104MP0004381_abnormal_hair_follicle0.85191119
105MP0000383_abnormal_hair_follicle0.85143125
106MP0000609_abnormal_liver_physiology0.83892678
107MP0002269_muscular_atrophy0.83532776
108MP0005384_cellular_phenotype0.81479700
109MP0003119_abnormal_digestive_system0.81312756
110MP0000647_abnormal_sebaceous_gland0.79628098
111MP0003646_muscle_fatigue0.79463001
112MP0002249_abnormal_larynx_morphology0.79423784
113MP0000428_abnormal_craniofacial_morphol0.78126827
114MP0000627_abnormal_mammary_gland0.77255515
115MP0000490_abnormal_crypts_of0.77120650
116MP0001286_abnormal_eye_development0.76472359
117MP0002163_abnormal_gland_morphology0.76307334
118MP0006036_abnormal_mitochondrial_physio0.75842477
119MP0002102_abnormal_ear_morphology0.75397111
120MP0003453_abnormal_keratinocyte_physiol0.73708210
121MP0000598_abnormal_liver_morphology0.73674061
122MP0005319_abnormal_enzyme/_coenzyme0.72712981
123MP0010329_abnormal_lipoprotein_level0.72066702
124MP0002970_abnormal_white_adipose0.72031191
125MP0000003_abnormal_adipose_tissue0.70164218
126MP0001216_abnormal_epidermal_layer0.69288759
127MP0004264_abnormal_extraembryonic_tissu0.68439420
128MP0002161_abnormal_fertility/fecundity0.68392353
129MP0009703_decreased_birth_body0.66283243
130MP0002127_abnormal_cardiovascular_syste0.66016969
131MP0002653_abnormal_ependyma_morphology0.65715073
132MP0003937_abnormal_limbs/digits/tail_de0.64563643
133MP0003329_amyloid_beta_deposits0.61543185
134MP0005330_cardiomyopathy0.60188384
135MP0003828_pulmonary_edema0.59949915
136MP0002160_abnormal_reproductive_system0.58893812
137MP0002019_abnormal_tumor_incidence0.57201463
138MP0002139_abnormal_hepatobiliary_system0.56869132
139MP0001293_anophthalmia0.54477255
140MP0003191_abnormal_cellular_cholesterol0.54001595
141MP0001727_abnormal_embryo_implantation0.53326770
142MP0005389_reproductive_system_phenotype0.52992753
143MP0001119_abnormal_female_reproductive0.52102333
144MP0005085_abnormal_gallbladder_physiolo0.51156166
145MP0009643_abnormal_urine_homeostasis0.50280881
146MP0000013_abnormal_adipose_tissue0.50053289
147MP0002092_abnormal_eye_morphology0.49647924
148MP0004197_abnormal_fetal_growth/weight/0.48602674

Predicted human phenotypes

RankGene SetZ-score
1Hyperglycinemia (HP:0002154)6.21314620
2Gout (HP:0001997)5.55790573
3Hyperglycinuria (HP:0003108)5.34966860
4Breast hypoplasia (HP:0003187)5.08918126
5Birth length less than 3rd percentile (HP:0003561)4.96930260
6Impulsivity (HP:0100710)4.74361949
7Cerebral hypomyelination (HP:0006808)4.69938800
8Abnormality of serine family amino acid metabolism (HP:0010894)4.54092440
9Abnormality of glycine metabolism (HP:0010895)4.54092440
10Carpal bone hypoplasia (HP:0001498)4.39775682
11Entropion (HP:0000621)4.21973829
12Chromosomal breakage induced by crosslinking agents (HP:0003221)4.15602654
13Tetraplegia (HP:0002445)4.06953822
14Progressive muscle weakness (HP:0003323)4.05216476
15Deep venous thrombosis (HP:0002625)4.01514094
16Rough bone trabeculation (HP:0100670)3.97278493
17Chromsome breakage (HP:0040012)3.78690428
18Pustule (HP:0200039)3.76218758
19Atrioventricular block (HP:0001678)3.72938461
20Bundle branch block (HP:0011710)3.67230576
21Ventricular fibrillation (HP:0001663)3.65512574
22Abnormality of serum amino acid levels (HP:0003112)3.50472041
23Abnormality of the umbilical cord (HP:0010881)3.48958198
24Ureteral duplication (HP:0000073)3.47910877
25Microvesicular hepatic steatosis (HP:0001414)3.42114521
26Aplasia/Hypoplasia of the patella (HP:0006498)3.27151218
27Muscle fiber splitting (HP:0003555)3.23657089
28Patellar aplasia (HP:0006443)3.20006703
29Areflexia of lower limbs (HP:0002522)3.15311537
30Segmental peripheral demyelination/remyelination (HP:0003481)3.10636107
31Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.07376302
32CNS hypomyelination (HP:0003429)3.03576633
33Asymmetry of the thorax (HP:0001555)3.03504727
34Hypoplasia of the capital femoral epiphysis (HP:0003090)3.02800540
35Abnormality of glycolysis (HP:0004366)3.01427136
36Multiple enchondromatosis (HP:0005701)3.00774408
37Abnormality of the distal phalanges of the toes (HP:0010182)2.99965376
38Death in infancy (HP:0001522)2.98958907
39Mutism (HP:0002300)2.96750663
40Increased nuchal translucency (HP:0010880)2.94372388
41Abnormal trabecular bone morphology (HP:0100671)2.93433680
42Ependymoma (HP:0002888)2.92116731
43Premature rupture of membranes (HP:0001788)2.90680907
44Sparse lateral eyebrow (HP:0005338)2.89407684
45Abnormality of the labia minora (HP:0012880)2.86942553
46Hyperuricemia (HP:0002149)2.84334310
47Increased purine levels (HP:0004368)2.84334310
48Short nail (HP:0001799)2.81872152
49Prolonged partial thromboplastin time (HP:0003645)2.76655318
50Osteolytic defects of the hand bones (HP:0009699)2.76488395
51Osteolytic defects of the phalanges of the hand (HP:0009771)2.76488395
52Megaloblastic anemia (HP:0001889)2.76453713
53Premature ovarian failure (HP:0008209)2.73904322
54Secondary amenorrhea (HP:0000869)2.72264899
55Cholecystitis (HP:0001082)2.69322840
56Abnormal gallbladder physiology (HP:0012438)2.69322840
57Irregular epiphyses (HP:0010582)2.68443291
58Increased serum pyruvate (HP:0003542)2.66818158
59Delusions (HP:0000746)2.65457250
60Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.63649568
61Abnormality of alanine metabolism (HP:0010916)2.63649568
62Hyperalaninemia (HP:0003348)2.63649568
63Nephroblastoma (Wilms tumor) (HP:0002667)2.60975853
64Selective tooth agenesis (HP:0001592)2.53175268
65Hyperacusis (HP:0010780)2.51189659
66Flat capital femoral epiphysis (HP:0003370)2.49776603
67Pelvic girdle muscle weakness (HP:0003749)2.49112697
68Small epiphyses (HP:0010585)2.49035780
69Oligodactyly (hands) (HP:0001180)2.48847747
70Meckel diverticulum (HP:0002245)2.48396473
71Restlessness (HP:0000711)2.47881574
72Global brain atrophy (HP:0002283)2.47579537
73Glucose intolerance (HP:0000833)2.46517329
74Abnormality of the anterior horn cell (HP:0006802)2.45590149
75Degeneration of anterior horn cells (HP:0002398)2.45590149
76Aplasia/Hypoplasia involving the musculature (HP:0001460)2.44242656
77Hypobetalipoproteinemia (HP:0003563)2.43109752
78Reduced subcutaneous adipose tissue (HP:0003758)2.41955583
79Alopecia of scalp (HP:0002293)2.41614199
80Submucous cleft hard palate (HP:0000176)2.39278043
81Shoulder girdle muscle weakness (HP:0003547)2.39102276
82Abnormality of the proximal phalanges of the hand (HP:0009834)2.38137343
83Stillbirth (HP:0003826)2.36864987
84Embryonal renal neoplasm (HP:0011794)2.35859014
85Personality changes (HP:0000751)2.34966751
86Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.33782534
87Absent epiphyses (HP:0010577)2.33782534
88Abnormality of aromatic amino acid family metabolism (HP:0004338)2.33646055
89Heart block (HP:0012722)2.31278965
90Reticulocytopenia (HP:0001896)2.30044239
91Congenital, generalized hypertrichosis (HP:0004540)2.29800115
92Hyperglycemia (HP:0003074)2.29746186
93Abnormality of the ileum (HP:0001549)2.29505179
94Dysautonomia (HP:0002459)2.25250350
95Difficulty climbing stairs (HP:0003551)2.23193866
96Abnormality of the preputium (HP:0100587)2.22187528
97Sparse eyelashes (HP:0000653)2.21605940
98Absent radius (HP:0003974)2.21062238
99Brittle hair (HP:0002299)2.20844571
100Short clavicles (HP:0000894)2.20049428
101Type I transferrin isoform profile (HP:0003642)2.19139592
102Abnormalities of placenta or umbilical cord (HP:0001194)2.18895313
103Progressive external ophthalmoplegia (HP:0000590)2.18604709
104Pancreatic fibrosis (HP:0100732)2.18265889
105Microretrognathia (HP:0000308)2.15804974
106Overlapping toe (HP:0001845)2.14728613
107Abnormal spermatogenesis (HP:0008669)2.14710225
108Abnormal atrioventricular conduction (HP:0005150)2.13383827
109Septate vagina (HP:0001153)2.12849638
110Pancreatic islet-cell hyperplasia (HP:0004510)2.12746146
111Insulin-resistant diabetes mellitus (HP:0000831)2.10741038
112Prolonged neonatal jaundice (HP:0006579)2.09375855
113Deviation of the thumb (HP:0009603)2.09086125
114Abnormality of the musculature of the pelvis (HP:0001469)2.08834296
115Abnormality of the hip-girdle musculature (HP:0001445)2.08834296
116CNS demyelination (HP:0007305)2.07291924
117Abnormality of monocarboxylic acid metabolism (HP:0010996)2.05543275
118Absent forearm bone (HP:0003953)2.05468427
119Aplasia involving forearm bones (HP:0009822)2.05468427
120Proximal placement of thumb (HP:0009623)2.04489074
121Spinal muscular atrophy (HP:0007269)2.04196905
122Oligodactyly (HP:0012165)2.00863792
123Postnatal microcephaly (HP:0005484)1.97665469
124Aplasia/Hypoplasia of the uvula (HP:0010293)1.97523395
125Flat acetabular roof (HP:0003180)1.97197376
126Patent foramen ovale (HP:0001655)1.96677061
127Male infertility (HP:0003251)1.95801347
128Capillary hemangiomas (HP:0005306)1.95271814
129Split foot (HP:0001839)1.94665216
130Spastic tetraparesis (HP:0001285)1.93957660
131Abnormal lung lobation (HP:0002101)1.93204681
132Abnormal tarsal ossification (HP:0008369)1.92572457
133Overriding aorta (HP:0002623)1.92328480
134Atrophy/Degeneration involving motor neurons (HP:0007373)1.91765556
135Facial hemangioma (HP:0000329)1.90900334
136Abnormality of methionine metabolism (HP:0010901)1.87758179
137Choanal stenosis (HP:0000452)1.87336670
138Abnormality of the salivary glands (HP:0010286)1.85848872
139Microglossia (HP:0000171)1.84064943
140Right ventricular cardiomyopathy (HP:0011663)1.83112673
141Colon cancer (HP:0003003)1.82727624
142Abnormality of cochlea (HP:0000375)1.81394624
143Abnormality of reticulocytes (HP:0004312)1.81306490
144Trismus (HP:0000211)1.81255243
145Renal duplication (HP:0000075)1.79381946
146Ulnar bowing (HP:0003031)1.78971640
147Embryonal neoplasm (HP:0002898)1.78923881
148Aplasia/Hypoplasia of the sacrum (HP:0008517)1.77081122
149Choanal atresia (HP:0000453)1.76733446
150Duplication of thumb phalanx (HP:0009942)1.74124163
151Ragged-red muscle fibers (HP:0003200)1.73767029
152Vaginal fistula (HP:0004320)1.73358881
153Back pain (HP:0003418)1.73056185
154Generalized hypotonia (HP:0001290)1.72773741
155Horseshoe kidney (HP:0000085)1.71318663
156Facial cleft (HP:0002006)1.71141175
157Abnormality of chromosome stability (HP:0003220)1.70393984
158Abnormality of the lacrimal duct (HP:0011481)1.67585338
159Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67345279
160Abnormal protein N-linked glycosylation (HP:0012347)1.67345279
161Abnormal protein glycosylation (HP:0012346)1.67345279
162Abnormal glycosylation (HP:0012345)1.67345279
163Abnormality of the carotid arteries (HP:0005344)1.65736491
164Broad distal phalanx of finger (HP:0009836)1.65584762
165Anal stenosis (HP:0002025)1.64868303
166Abnormal foot bone ossification (HP:0010675)1.64476184
167Atresia of the external auditory canal (HP:0000413)1.64111614
168Malignant gastrointestinal tract tumors (HP:0006749)1.63797623
169Gastrointestinal carcinoma (HP:0002672)1.63797623
170Hepatoblastoma (HP:0002884)1.62215887
171Limited elbow extension (HP:0001377)1.61691311
172Testicular atrophy (HP:0000029)1.61288987
173J-shaped sella turcica (HP:0002680)1.59862539
174Hypoplastic pelvis (HP:0008839)1.59809791
175Hypercholesterolemia (HP:0003124)1.59732807
176Medulloblastoma (HP:0002885)1.58801247
177Insomnia (HP:0100785)1.58575303
178Hypoparathyroidism (HP:0000829)1.58570062
179Reticulocytosis (HP:0001923)1.58220188
180Reduced antithrombin III activity (HP:0001976)1.57797725

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB17.71594580
2AKT34.59123787
3WEE14.52120468
4TRIB33.72234313
5TSSK63.52724478
6SMG13.48017682
7NEK22.92238958
8PLK42.91962280
9EIF2AK12.80257174
10BRSK22.66075731
11CDK122.59042551
12VRK22.41396825
13EEF2K2.20537439
14STK162.19294913
15PBK2.19109259
16EPHA22.14037475
17PDK32.02177838
18PDK42.02177838
19PLK31.99887963
20PKN21.98248194
21MKNK21.96998218
22SIK11.96863787
23ICK1.96652264
24BRSK11.93499728
25NEK11.91432192
26MAP3K101.90851656
27PLK11.89930767
28ACVR1B1.83073120
29TTK1.82373605
30CCNB11.76045677
31RPS6KB21.74436922
32PDK21.66086148
33EIF2AK31.56226179
34MKNK11.52983795
35PAK41.52402372
36NME21.52232134
37ARAF1.51467023
38LATS21.49727824
39DYRK31.47335015
40TAF11.46993342
41ZAK1.45403177
42SRPK11.45146278
43PINK11.43688778
44SCYL21.40982205
45STK31.40795677
46CHEK21.25114894
47BRAF1.20184786
48PNCK1.18194638
49AURKB1.07240179
50IRAK31.05486050
51CSNK1G31.05458687
52STK38L1.01822536
53AURKA1.00572435
54ALK0.94029220
55CDC70.90055567
56TESK20.88984471
57PDGFRA0.88501867
58CDK40.88368205
59PIM20.88366161
60RIPK10.85220106
61CSNK1G10.84207717
62MAP3K90.83301725
63CDK70.82040111
64CSNK1A1L0.81728255
65RPS6KA40.81181194
66DAPK10.78662493
67CHEK10.78206520
68PRKCI0.76167485
69PASK0.75954564
70CAMKK20.75808025
71CSNK1G20.73715333
72MST1R0.73668277
73BCKDK0.73603093
74BMX0.72842282
75PAK10.70967512
76MET0.70193448
77MAP3K80.67510446
78FGFR10.65795431
79PRKAA10.65531208
80TYRO30.64800238
81KDR0.61309175
82RAF10.60736359
83PTK20.59261321
84CAMK1G0.58091306
85MAPKAPK30.57977990
86CDK20.57718097
87ERN10.57640845
88BRD40.55892031
89TESK10.55738874
90WNK30.54248297
91EIF2AK20.53908249
92PTK60.53155282
93FGFR20.52271453
94CSNK1E0.52041043
95NEK60.51443354
96CDK30.50238524
97CDK60.48845346
98ATR0.48800496
99PRKCG0.46196491
100TAOK10.45654164
101STK380.44794130
102CDK90.44508153
103STK240.42050135
104CDK10.41739385
105PRPF4B0.40276274
106VRK10.39497310
107CDK80.38702490
108NME10.37098431
109CSNK2A20.36772956
110PAK60.36087438
111CSNK2A10.35397880
112CSNK1A10.34760822
113SIK30.33882933
114CAMK1D0.33532023
115PIM10.33415008
116PRKDC0.32471727
117AKT20.32116312
118RET0.31829774
119LATS10.31211465
120MTOR0.30469836
121PRKD30.29745123
122MAP2K20.29480066
123MELK0.26408152
124CLK10.26206773
125MAPK110.26056679
126RPS6KB10.25569703
127FGFR30.25311607
128CDK11A0.25263051
129MAP3K30.24020682
130ATM0.23787366
131STK100.23741282
132DYRK20.20350859
133FGFR40.20343783
134ABL20.20156745
135PDPK10.17944668
136MAPK100.17235604
137MAPK90.15463961
138RIPK40.15243935
139KSR20.13624793
140MAPK40.13092033
141PAK20.12915085
142RPS6KA50.12142544
143MARK30.10969964
144MAP3K50.10274213
145STK40.08569984
146GSK3B0.08548268
147STK110.08241814

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007508.34813505
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.37011578
3RNA polymerase_Homo sapiens_hsa030204.26944706
4Folate biosynthesis_Homo sapiens_hsa007903.70779299
5RNA transport_Homo sapiens_hsa030132.86849258
6Regulation of autophagy_Homo sapiens_hsa041402.79008500
7Proteasome_Homo sapiens_hsa030502.70405479
8Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.40107782
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.35277395
10Glycerophospholipid metabolism_Homo sapiens_hsa005642.28257588
11Cell cycle_Homo sapiens_hsa041102.22806558
12Pyrimidine metabolism_Homo sapiens_hsa002402.15770847
13Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.06641653
14Pentose phosphate pathway_Homo sapiens_hsa000301.84311895
15Drug metabolism - other enzymes_Homo sapiens_hsa009831.82110813
16Spliceosome_Homo sapiens_hsa030401.81447611
17DNA replication_Homo sapiens_hsa030301.76804835
18Basal transcription factors_Homo sapiens_hsa030221.71158601
19Cysteine and methionine metabolism_Homo sapiens_hsa002701.69352196
20N-Glycan biosynthesis_Homo sapiens_hsa005101.68904106
21p53 signaling pathway_Homo sapiens_hsa041151.65786431
22Purine metabolism_Homo sapiens_hsa002301.58657299
23Pyruvate metabolism_Homo sapiens_hsa006201.53877520
24Biosynthesis of amino acids_Homo sapiens_hsa012301.52918436
25Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.52766943
26Base excision repair_Homo sapiens_hsa034101.45517122
27Nucleotide excision repair_Homo sapiens_hsa034201.34978788
28Oocyte meiosis_Homo sapiens_hsa041141.33858500
29Phenylalanine metabolism_Homo sapiens_hsa003601.32686347
30Homologous recombination_Homo sapiens_hsa034401.30827106
31Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.30162649
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.28821355
33Mismatch repair_Homo sapiens_hsa034301.28659549
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.28519520
35Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.28251448
36Thyroid cancer_Homo sapiens_hsa052161.25697977
37Lysine degradation_Homo sapiens_hsa003101.14597286
38Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.12095498
39Central carbon metabolism in cancer_Homo sapiens_hsa052301.11982502
40Sulfur relay system_Homo sapiens_hsa041221.06163801
41Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.04114868
42Epstein-Barr virus infection_Homo sapiens_hsa051690.95319369
43Carbon metabolism_Homo sapiens_hsa012000.92485029
44Circadian rhythm_Homo sapiens_hsa047100.92029896
45Fructose and mannose metabolism_Homo sapiens_hsa000510.91602042
46Butanoate metabolism_Homo sapiens_hsa006500.91106092
47* Vitamin digestion and absorption_Homo sapiens_hsa049770.90704747
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.88338777
49Fanconi anemia pathway_Homo sapiens_hsa034600.84456481
50Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.84028255
51Tyrosine metabolism_Homo sapiens_hsa003500.83219402
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.81174313
53Glycerolipid metabolism_Homo sapiens_hsa005610.80924748
54mRNA surveillance pathway_Homo sapiens_hsa030150.66020372
55One carbon pool by folate_Homo sapiens_hsa006700.64567604
56Lysosome_Homo sapiens_hsa041420.63810449
57Selenocompound metabolism_Homo sapiens_hsa004500.62067380
58Bladder cancer_Homo sapiens_hsa052190.61690079
59Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61399531
60Complement and coagulation cascades_Homo sapiens_hsa046100.60989464
61RNA degradation_Homo sapiens_hsa030180.59716343
62Other glycan degradation_Homo sapiens_hsa005110.59640730
63Metabolic pathways_Homo sapiens_hsa011000.57668215
64mTOR signaling pathway_Homo sapiens_hsa041500.55663064
65Adherens junction_Homo sapiens_hsa045200.55098723
66Ribosome_Homo sapiens_hsa030100.54981282
67Endometrial cancer_Homo sapiens_hsa052130.53104005
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52857650
69Chronic myeloid leukemia_Homo sapiens_hsa052200.51509210
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.49617206
71Renin-angiotensin system_Homo sapiens_hsa046140.47806241
72beta-Alanine metabolism_Homo sapiens_hsa004100.46333771
73Arginine and proline metabolism_Homo sapiens_hsa003300.45908383
74Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.45610933
75Acute myeloid leukemia_Homo sapiens_hsa052210.45551323
76Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.44780037
77Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43901340
78Cyanoamino acid metabolism_Homo sapiens_hsa004600.43615120
79Basal cell carcinoma_Homo sapiens_hsa052170.43428837
80MicroRNAs in cancer_Homo sapiens_hsa052060.42180911
81Colorectal cancer_Homo sapiens_hsa052100.39608844
82Prostate cancer_Homo sapiens_hsa052150.37938904
83Mineral absorption_Homo sapiens_hsa049780.36839360
84Antigen processing and presentation_Homo sapiens_hsa046120.36576889
85FoxO signaling pathway_Homo sapiens_hsa040680.36029359
86Insulin signaling pathway_Homo sapiens_hsa049100.34959144
87Glutathione metabolism_Homo sapiens_hsa004800.34555289
88Non-small cell lung cancer_Homo sapiens_hsa052230.31680615
89Galactose metabolism_Homo sapiens_hsa000520.29094916
90Fatty acid metabolism_Homo sapiens_hsa012120.28808554
91Wnt signaling pathway_Homo sapiens_hsa043100.28707514
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.28552330
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28154119
94Inositol phosphate metabolism_Homo sapiens_hsa005620.27609315
95Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.26046541
96Notch signaling pathway_Homo sapiens_hsa043300.25905427
97Glucagon signaling pathway_Homo sapiens_hsa049220.25485100
98Retinol metabolism_Homo sapiens_hsa008300.20523669
99Arginine biosynthesis_Homo sapiens_hsa002200.20523101
100Linoleic acid metabolism_Homo sapiens_hsa005910.20086282
101Sphingolipid metabolism_Homo sapiens_hsa006000.19647425
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.16962733
103AMPK signaling pathway_Homo sapiens_hsa041520.15684656
104Viral carcinogenesis_Homo sapiens_hsa052030.14772819
105Fatty acid biosynthesis_Homo sapiens_hsa000610.13280255
106Collecting duct acid secretion_Homo sapiens_hsa049660.10849803
107Fat digestion and absorption_Homo sapiens_hsa049750.09275281
108Steroid biosynthesis_Homo sapiens_hsa001000.08839169
109Herpes simplex infection_Homo sapiens_hsa051680.07924592
110HIF-1 signaling pathway_Homo sapiens_hsa040660.07828592
111alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.07764725
112Propanoate metabolism_Homo sapiens_hsa006400.07366817
113PPAR signaling pathway_Homo sapiens_hsa033200.07355299
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.04882846
115Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.03823385
116Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.03654704
117Thyroid hormone signaling pathway_Homo sapiens_hsa049190.03278772
118Fatty acid elongation_Homo sapiens_hsa000620.03154437
119Prion diseases_Homo sapiens_hsa050200.02822714
120Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.02533125
121Hippo signaling pathway_Homo sapiens_hsa043900.02001702
122Renal cell carcinoma_Homo sapiens_hsa052110.01433587
123Arachidonic acid metabolism_Homo sapiens_hsa005900.00683575
124Fatty acid degradation_Homo sapiens_hsa000710.00603079
125Small cell lung cancer_Homo sapiens_hsa05222-0.0225102
126Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.0200077
127Maturity onset diabetes of the young_Homo sapiens_hsa04950-0.0141156
128Non-homologous end-joining_Homo sapiens_hsa03450-0.0119241
129Adipocytokine signaling pathway_Homo sapiens_hsa04920-0.0059469

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