Rank | Gene Set | Z-score |
---|---|---|
1 | hemidesmosome assembly (GO:0031581) | 5.12069369 |
2 | desmosome organization (GO:0002934) | 4.94404848 |
3 | mitotic chromosome condensation (GO:0007076) | 4.45371797 |
4 | COPI coating of Golgi vesicle (GO:0048205) | 4.33097194 |
5 | Golgi transport vesicle coating (GO:0048200) | 4.33097194 |
6 | cellular protein complex localization (GO:0034629) | 4.11865568 |
7 | cell-substrate junction assembly (GO:0007044) | 3.95388429 |
8 | nuclear pore complex assembly (GO:0051292) | 3.86531617 |
9 | regulation of translational fidelity (GO:0006450) | 3.77297211 |
10 | protein complex localization (GO:0031503) | 3.76224971 |
11 | proline biosynthetic process (GO:0006561) | 3.68182080 |
12 | skin morphogenesis (GO:0043589) | 3.65107067 |
13 | adherens junction assembly (GO:0034333) | 3.60467899 |
14 | cell-substrate adherens junction assembly (GO:0007045) | 3.58537628 |
15 | focal adhesion assembly (GO:0048041) | 3.58537628 |
16 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.56507957 |
17 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.52398063 |
18 | activation of Rac GTPase activity (GO:0032863) | 3.42083336 |
19 | nuclear pore organization (GO:0006999) | 3.41907288 |
20 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.23759397 |
21 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.21909574 |
22 | protein retention in ER lumen (GO:0006621) | 3.18144112 |
23 | L-serine metabolic process (GO:0006563) | 3.18127406 |
24 | protein localization to chromosome, centromeric region (GO:0071459) | 3.16694686 |
25 | mitotic sister chromatid segregation (GO:0000070) | 3.15183128 |
26 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.04074440 |
27 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.01202808 |
28 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.98369706 |
29 | positive thymic T cell selection (GO:0045059) | 2.98033308 |
30 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.97554539 |
31 | protein localization to microtubule (GO:0035372) | 2.96372512 |
32 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.89998790 |
33 | germ cell migration (GO:0008354) | 2.87337815 |
34 | lymph vessel development (GO:0001945) | 2.85831376 |
35 | epithelial cell-cell adhesion (GO:0090136) | 2.85074864 |
36 | protein export from nucleus (GO:0006611) | 2.83333682 |
37 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.82583312 |
38 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.81966200 |
39 | chromosome condensation (GO:0030261) | 2.81630351 |
40 | pore complex assembly (GO:0046931) | 2.78374286 |
41 | regulation of early endosome to late endosome transport (GO:2000641) | 2.77890538 |
42 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.74959748 |
43 | regulation of water loss via skin (GO:0033561) | 2.74448601 |
44 | DNA strand elongation (GO:0022616) | 2.73300750 |
45 | DNA unwinding involved in DNA replication (GO:0006268) | 2.72853123 |
46 | endothelium development (GO:0003158) | 2.72819075 |
47 | ER-nucleus signaling pathway (GO:0006984) | 2.71816116 |
48 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.71422352 |
49 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.71054094 |
50 | gap junction assembly (GO:0016264) | 2.70748112 |
51 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.70444343 |
52 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.68598893 |
53 | regulation of histone H3-K27 methylation (GO:0061085) | 2.67616984 |
54 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.66745324 |
55 | L-alpha-amino acid transmembrane transport (GO:1902475) | 2.65029133 |
56 | regulation of translational termination (GO:0006449) | 2.64688816 |
57 | ER overload response (GO:0006983) | 2.64220339 |
58 | apoptotic process involved in morphogenesis (GO:0060561) | 2.63406599 |
59 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.62263478 |
60 | DNA replication initiation (GO:0006270) | 2.61463335 |
61 | corticosteroid receptor signaling pathway (GO:0031958) | 2.58998758 |
62 | histone H3-K36 demethylation (GO:0070544) | 2.57732807 |
63 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.57428647 |
64 | G1 DNA damage checkpoint (GO:0044783) | 2.56566336 |
65 | COPII vesicle coating (GO:0048208) | 2.56172913 |
66 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.55042661 |
67 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.53911634 |
68 | L-serine transport (GO:0015825) | 2.52980879 |
69 | regulation of nuclease activity (GO:0032069) | 2.52815118 |
70 | protein localization to endosome (GO:0036010) | 2.51331853 |
71 | cellular response to unfolded protein (GO:0034620) | 2.51280957 |
72 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.49708085 |
73 | mRNA transcription (GO:0009299) | 2.49634563 |
74 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 2.46686008 |
75 | regulation of mitotic spindle organization (GO:0060236) | 2.46177104 |
76 | positive regulation of chromosome segregation (GO:0051984) | 2.44981921 |
77 | formation of translation preinitiation complex (GO:0001731) | 2.44922157 |
78 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059) | 2.44423955 |
79 | NLS-bearing protein import into nucleus (GO:0006607) | 2.43998834 |
80 | DNA geometric change (GO:0032392) | 2.43548796 |
81 | pre-miRNA processing (GO:0031054) | 2.43042876 |
82 | vesicle coating (GO:0006901) | 2.42032464 |
83 | endoderm formation (GO:0001706) | 2.41761436 |
84 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.41006857 |
85 | nuclear envelope reassembly (GO:0031468) | 2.40015275 |
86 | mitotic nuclear envelope reassembly (GO:0007084) | 2.40015275 |
87 | serine transport (GO:0032329) | 2.39319251 |
88 | heterochromatin organization (GO:0070828) | 2.39316410 |
89 | protein localization to kinetochore (GO:0034501) | 2.39281370 |
90 | mitotic sister chromatid cohesion (GO:0007064) | 2.37842731 |
91 | maternal placenta development (GO:0001893) | 2.37651904 |
92 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.37592425 |
93 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.36654074 |
94 | trophectodermal cell differentiation (GO:0001829) | 2.36546337 |
95 | positive regulation of keratinocyte differentiation (GO:0045618) | 2.36351077 |
96 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.36269237 |
97 | mammary gland epithelial cell proliferation (GO:0033598) | 2.35060451 |
98 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.34850512 |
99 | embryonic eye morphogenesis (GO:0048048) | 2.34511415 |
100 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.34363504 |
101 | embryonic foregut morphogenesis (GO:0048617) | 2.33359053 |
102 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.32653778 |
103 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.31243800 |
104 | male sex determination (GO:0030238) | 2.30789081 |
105 | positive T cell selection (GO:0043368) | 2.29024667 |
106 | mitotic nuclear envelope disassembly (GO:0007077) | 2.24043043 |
107 | hippo signaling (GO:0035329) | 2.20267691 |
108 | thymic T cell selection (GO:0045061) | 2.20172228 |
109 | membrane disassembly (GO:0030397) | 2.19695078 |
110 | nuclear envelope disassembly (GO:0051081) | 2.19695078 |
111 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.19069749 |
112 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.18534246 |
113 | mRNA stabilization (GO:0048255) | 2.18481949 |
114 | RNA stabilization (GO:0043489) | 2.18481949 |
115 | mesodermal cell differentiation (GO:0048333) | 2.16529454 |
116 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.15636134 |
117 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.13375518 |
118 | negative regulation of glial cell proliferation (GO:0060253) | 2.12441754 |
119 | response to laminar fluid shear stress (GO:0034616) | 2.12249365 |
120 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 2.11993886 |
121 | sister chromatid segregation (GO:0000819) | 2.11208817 |
122 | negative regulation of mRNA metabolic process (GO:1903312) | 2.10625642 |
123 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.10500482 |
124 | positive regulation of astrocyte differentiation (GO:0048711) | 2.09940392 |
125 | chromatin assembly (GO:0031497) | 2.08700884 |
126 | histone lysine demethylation (GO:0070076) | 2.08622852 |
127 | viral transcription (GO:0019083) | 2.07601154 |
128 | patterning of blood vessels (GO:0001569) | 2.07566471 |
129 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.07186129 |
130 | regulation of translational elongation (GO:0006448) | 2.07097302 |
131 | maturation of SSU-rRNA (GO:0030490) | 2.06345259 |
132 | cell adhesion mediated by integrin (GO:0033627) | 2.06311546 |
133 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.05891905 |
134 | translational termination (GO:0006415) | 2.05740863 |
135 | negative regulation of RNA splicing (GO:0033119) | 2.05274433 |
136 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.04962542 |
137 | establishment of apical/basal cell polarity (GO:0035089) | 2.04714417 |
138 | cellular response to nicotine (GO:0071316) | 2.04440870 |
139 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.04189081 |
140 | coronary vasculature morphogenesis (GO:0060977) | 2.03947203 |
141 | Notch signaling involved in heart development (GO:0061314) | 2.03169308 |
142 | histone demethylation (GO:0016577) | 2.02351146 |
143 | trabecula morphogenesis (GO:0061383) | 2.01937592 |
144 | formation of primary germ layer (GO:0001704) | 1.99839990 |
145 | positive regulation of odontogenesis (GO:0042482) | 1.99408065 |
146 | regulation of vitamin D biosynthetic process (GO:0060556) | 1.98399767 |
147 | positive regulation of histone deacetylation (GO:0031065) | 1.98113456 |
148 | dosage compensation (GO:0007549) | 1.97715429 |
149 | radial glial cell differentiation (GO:0060019) | 1.97540503 |
150 | embryonic process involved in female pregnancy (GO:0060136) | 1.96557859 |
151 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 1.96476439 |
152 | polarized epithelial cell differentiation (GO:0030859) | 1.96287728 |
153 | response to fluid shear stress (GO:0034405) | 1.96182706 |
154 | establishment of monopolar cell polarity (GO:0061162) | 1.96041641 |
155 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 1.96041641 |
156 | histone H2A monoubiquitination (GO:0035518) | 1.95967199 |
157 | negative regulation of mRNA processing (GO:0050686) | 1.95406177 |
158 | DNA duplex unwinding (GO:0032508) | 1.95108531 |
159 | peptidyl-arginine methylation (GO:0018216) | 1.94551829 |
160 | peptidyl-arginine N-methylation (GO:0035246) | 1.94551829 |
161 | negative thymic T cell selection (GO:0045060) | 1.94475847 |
162 | establishment of endothelial barrier (GO:0061028) | 1.92600942 |
163 | developmental programmed cell death (GO:0010623) | 1.92258597 |
164 | positive regulation of nuclease activity (GO:0032075) | 1.92082360 |
165 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 1.92043547 |
166 | regulation of RNA export from nucleus (GO:0046831) | 1.91968513 |
167 | tyrosine phosphorylation of STAT protein (GO:0007260) | 1.91464136 |
168 | T cell apoptotic process (GO:0070231) | 1.91331267 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.22861712 |
2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.36207634 |
3 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.12456358 |
4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.12027845 |
5 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 4.05550223 |
6 | MYC_22102868_ChIP-Seq_BL_Human | 3.54251620 |
7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.53503688 |
8 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.31907755 |
9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.17131421 |
10 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.45145000 |
11 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.43692583 |
12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.36521122 |
13 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.14738140 |
14 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.09890812 |
15 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.06067602 |
16 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.98267432 |
17 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.96544416 |
18 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.95668799 |
19 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.94809997 |
20 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.92999023 |
21 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.89421888 |
22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.89162407 |
23 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.88952674 |
24 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.88222063 |
25 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.87785686 |
26 | * SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.85184902 |
27 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.83052133 |
28 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.81770441 |
29 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.80185946 |
30 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.79043921 |
31 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.71353827 |
32 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.69951516 |
33 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.69406845 |
34 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.67866701 |
35 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.65984709 |
36 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.64910988 |
37 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.63016374 |
38 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.60930215 |
39 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.59980066 |
40 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.56659062 |
41 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.52663311 |
42 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.49095478 |
43 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.48631469 |
44 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.46932642 |
45 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.45940711 |
46 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.44606764 |
47 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.43435046 |
48 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.42955568 |
49 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.42934911 |
50 | MAF_26560356_Chip-Seq_TH1_Human | 1.42469005 |
51 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.42100642 |
52 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.41974448 |
53 | UTX_26944678_Chip-Seq_JUKART_Human | 1.41278503 |
54 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.41058742 |
55 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.40994273 |
56 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.40994273 |
57 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.39480647 |
58 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.38702782 |
59 | MYB_26560356_Chip-Seq_TH2_Human | 1.38556797 |
60 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.38020911 |
61 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.37903128 |
62 | KDM2B_26808549_Chip-Seq_K562_Human | 1.37116476 |
63 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.36700260 |
64 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.35405872 |
65 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.34514173 |
66 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.32716419 |
67 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31278175 |
68 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.31133516 |
69 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.29700735 |
70 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.27596981 |
71 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.27448839 |
72 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.25924434 |
73 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.25679756 |
74 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.25677331 |
75 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.25304995 |
76 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.22301238 |
77 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.21376714 |
78 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.21376714 |
79 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.21376714 |
80 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.20524418 |
81 | MYB_26560356_Chip-Seq_TH1_Human | 1.20442976 |
82 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.19648411 |
83 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.19452121 |
84 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.18266235 |
85 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.18099911 |
86 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.17735380 |
87 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.15365093 |
88 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.15245536 |
89 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.14297491 |
90 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.11970565 |
91 | * CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.10745944 |
92 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.10497554 |
93 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.10370566 |
94 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.09861168 |
95 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.09077312 |
96 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.08671371 |
97 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.07844334 |
98 | * EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.07158156 |
99 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.06703736 |
100 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.06056463 |
101 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.05613889 |
102 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05392049 |
103 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.03747724 |
104 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.03068876 |
105 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.03059736 |
106 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.02290463 |
107 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.02202251 |
108 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.01882558 |
109 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.01158559 |
110 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.00506922 |
111 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.00191661 |
112 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 0.97790056 |
113 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.97212570 |
114 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.97083164 |
115 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.96161556 |
116 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.95263522 |
117 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.94494617 |
118 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.94072316 |
119 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.94069892 |
120 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.94050156 |
121 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.93519107 |
122 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.93348541 |
123 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.93285042 |
124 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 0.93152566 |
125 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.92348245 |
126 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.91718055 |
127 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.91158587 |
128 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.91109485 |
129 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.90837340 |
130 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.90556082 |
131 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.90521059 |
132 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.89983677 |
133 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.89464864 |
134 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.89323744 |
135 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.86675296 |
136 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.86596446 |
137 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.86283707 |
138 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.86014873 |
139 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.85416808 |
140 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.83633265 |
141 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.82683740 |
142 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.82428776 |
143 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.81701165 |
144 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.81565498 |
145 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.81299736 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005623_abnormal_meninges_morphology | 2.79258178 |
2 | MP0008438_abnormal_cutaneous_collagen | 2.69579038 |
3 | MP0002796_impaired_skin_barrier | 2.59910899 |
4 | MP0003300_gastrointestinal_ulcer | 2.58802565 |
5 | MP0010352_gastrointestinal_tract_polyps | 2.49126970 |
6 | MP0003303_peritoneal_inflammation | 2.42301809 |
7 | MP0000579_abnormal_nail_morphology | 2.38297067 |
8 | MP0005076_abnormal_cell_differentiation | 2.36298070 |
9 | MP0005501_abnormal_skin_physiology | 2.06252283 |
10 | MP0002060_abnormal_skin_morphology | 2.03443975 |
11 | MP0001849_ear_inflammation | 1.97432666 |
12 | MP0003453_abnormal_keratinocyte_physiol | 1.95841642 |
13 | MP0004808_abnormal_hematopoietic_stem | 1.92974843 |
14 | MP0004272_abnormal_basement_membrane | 1.88821362 |
15 | MP0004185_abnormal_adipocyte_glucose | 1.87865914 |
16 | MP0003566_abnormal_cell_adhesion | 1.86102873 |
17 | MP0002877_abnormal_melanocyte_morpholog | 1.85693953 |
18 | MP0008057_abnormal_DNA_replication | 1.79758819 |
19 | MP0009278_abnormal_bone_marrow | 1.74961006 |
20 | MP0005409_darkened_coat_color | 1.74032895 |
21 | MP0002396_abnormal_hematopoietic_system | 1.69429105 |
22 | MP0003091_abnormal_cell_migration | 1.66626287 |
23 | MP0005171_absent_coat_pigmentation | 1.65355615 |
24 | MP0000733_abnormal_muscle_development | 1.63377022 |
25 | MP0003763_abnormal_thymus_physiology | 1.61709703 |
26 | MP0004264_abnormal_extraembryonic_tissu | 1.60358058 |
27 | MP0001216_abnormal_epidermal_layer | 1.60016108 |
28 | MP0005451_abnormal_body_composition | 1.58547181 |
29 | MP0005275_abnormal_skin_tensile | 1.52271221 |
30 | MP0000762_abnormal_tongue_morphology | 1.50264787 |
31 | MP0004858_abnormal_nervous_system | 1.48540551 |
32 | MP0006054_spinal_hemorrhage | 1.47595894 |
33 | MP0000569_abnormal_digit_pigmentation | 1.43707487 |
34 | MP0009672_abnormal_birth_weight | 1.43582011 |
35 | MP0001873_stomach_inflammation | 1.41779478 |
36 | MP0003705_abnormal_hypodermis_morpholog | 1.40049959 |
37 | MP0008961_abnormal_basal_metabolism | 1.38395265 |
38 | MP0000350_abnormal_cell_proliferation | 1.35689709 |
39 | MP0003984_embryonic_growth_retardation | 1.34803632 |
40 | MP0000467_abnormal_esophagus_morphology | 1.34219701 |
41 | MP0010094_abnormal_chromosome_stability | 1.34211242 |
42 | MP0003111_abnormal_nucleus_morphology | 1.33412335 |
43 | MP0002088_abnormal_embryonic_growth/wei | 1.32376145 |
44 | MP0004197_abnormal_fetal_growth/weight/ | 1.32241977 |
45 | MP0001879_abnormal_lymphatic_vessel | 1.31628127 |
46 | MP0000566_synostosis | 1.31484772 |
47 | MP0001730_embryonic_growth_arrest | 1.30136611 |
48 | MP0002086_abnormal_extraembryonic_tissu | 1.29775578 |
49 | MP0002084_abnormal_developmental_patter | 1.28941095 |
50 | MP0004957_abnormal_blastocyst_morpholog | 1.28800202 |
51 | MP0002098_abnormal_vibrissa_morphology | 1.28376900 |
52 | MP0002925_abnormal_cardiovascular_devel | 1.27644196 |
53 | MP0000703_abnormal_thymus_morphology | 1.27180624 |
54 | MP0005380_embryogenesis_phenotype | 1.25246307 |
55 | MP0001672_abnormal_embryogenesis/_devel | 1.25246307 |
56 | MP0000537_abnormal_urethra_morphology | 1.23716909 |
57 | MP0002166_altered_tumor_susceptibility | 1.19552278 |
58 | MP0002009_preneoplasia | 1.19485401 |
59 | MP0003077_abnormal_cell_cycle | 1.18762218 |
60 | MP0009053_abnormal_anal_canal | 1.17645360 |
61 | MP0000377_abnormal_hair_follicle | 1.16130805 |
62 | MP0002405_respiratory_system_inflammati | 1.15209097 |
63 | MP0010771_integument_phenotype | 1.12770519 |
64 | * MP0005621_abnormal_cell_physiology | 1.12662029 |
65 | MP0002085_abnormal_embryonic_tissue | 1.10296620 |
66 | MP0001697_abnormal_embryo_size | 1.09685131 |
67 | MP0010307_abnormal_tumor_latency | 1.09458727 |
68 | MP0003866_abnormal_defecation | 1.07754178 |
69 | MP0000003_abnormal_adipose_tissue | 1.07161136 |
70 | MP0000678_abnormal_parathyroid_gland | 1.06529405 |
71 | MP0003279_aneurysm | 1.04851426 |
72 | MP0002933_joint_inflammation | 1.04364516 |
73 | MP0001915_intracranial_hemorrhage | 1.04122224 |
74 | MP0009931_abnormal_skin_appearance | 1.02852969 |
75 | MP0003115_abnormal_respiratory_system | 1.02735226 |
76 | MP0001348_abnormal_lacrimal_gland | 1.02646410 |
77 | MP0000627_abnormal_mammary_gland | 1.01469614 |
78 | MP0003693_abnormal_embryo_hatching | 0.98880367 |
79 | * MP0002398_abnormal_bone_marrow | 0.98426371 |
80 | MP0003941_abnormal_skin_development | 0.98339753 |
81 | MP0003942_abnormal_urinary_system | 0.98153775 |
82 | MP0000490_abnormal_crypts_of | 0.97812064 |
83 | MP0010030_abnormal_orbit_morphology | 0.97688494 |
84 | MP0003045_fibrosis | 0.96309799 |
85 | MP0004947_skin_inflammation | 0.95990297 |
86 | MP0002089_abnormal_postnatal_growth/wei | 0.95650700 |
87 | MP0002080_prenatal_lethality | 0.95032766 |
88 | MP0003315_abnormal_perineum_morphology | 0.94997617 |
89 | MP0000534_abnormal_ureter_morphology | 0.94804075 |
90 | MP0008007_abnormal_cellular_replicative | 0.93704692 |
91 | MP0010630_abnormal_cardiac_muscle | 0.92934374 |
92 | MP0009333_abnormal_splenocyte_physiolog | 0.92547069 |
93 | MP0004782_abnormal_surfactant_physiolog | 0.91839312 |
94 | MP0005377_hearing/vestibular/ear_phenot | 0.91696905 |
95 | MP0003878_abnormal_ear_physiology | 0.91696905 |
96 | MP0009384_cardiac_valve_regurgitation | 0.91613509 |
97 | MP0003123_paternal_imprinting | 0.91494051 |
98 | MP0003950_abnormal_plasma_membrane | 0.90592031 |
99 | MP0003935_abnormal_craniofacial_develop | 0.90322763 |
100 | MP0004084_abnormal_cardiac_muscle | 0.88798187 |
101 | MP0000858_altered_metastatic_potential | 0.88368423 |
102 | MP0001784_abnormal_fluid_regulation | 0.86696913 |
103 | MP0005408_hypopigmentation | 0.86049447 |
104 | MP0005167_abnormal_blood-brain_barrier | 0.85330912 |
105 | MP0002697_abnormal_eye_size | 0.83118745 |
106 | MP0000372_irregular_coat_pigmentation | 0.82852107 |
107 | MP0002006_tumorigenesis | 0.82101302 |
108 | * MP0005384_cellular_phenotype | 0.81531405 |
109 | MP0005023_abnormal_wound_healing | 0.81414518 |
110 | MP0001299_abnormal_eye_distance/ | 0.79791934 |
111 | MP0005397_hematopoietic_system_phenotyp | 0.79495717 |
112 | MP0001545_abnormal_hematopoietic_system | 0.79495717 |
113 | MP0000383_abnormal_hair_follicle | 0.79448641 |
114 | MP0000015_abnormal_ear_pigmentation | 0.78297218 |
115 | MP0004233_abnormal_muscle_weight | 0.77721367 |
116 | MP0001243_abnormal_dermal_layer | 0.77436091 |
117 | MP0002722_abnormal_immune_system | 0.77294122 |
118 | MP0003890_abnormal_embryonic-extraembry | 0.76914746 |
119 | MP0000432_abnormal_head_morphology | 0.76267626 |
120 | MP0001661_extended_life_span | 0.76136625 |
121 | MP0002896_abnormal_bone_mineralization | 0.75978232 |
122 | MP0003121_genomic_imprinting | 0.75561834 |
123 | MP0003828_pulmonary_edema | 0.74953631 |
124 | MP0000767_abnormal_smooth_muscle | 0.74912552 |
125 | MP0005257_abnormal_intraocular_pressure | 0.74905845 |
126 | MP0008932_abnormal_embryonic_tissue | 0.74768140 |
127 | MP0002113_abnormal_skeleton_development | 0.74337691 |
128 | MP0000266_abnormal_heart_morphology | 0.74283100 |
129 | MP0003943_abnormal_hepatobiliary_system | 0.73664409 |
130 | MP0001340_abnormal_eyelid_morphology | 0.73614199 |
131 | MP0003448_altered_tumor_morphology | 0.73529799 |
132 | MP0005375_adipose_tissue_phenotype | 0.73275414 |
133 | MP0008770_decreased_survivor_rate | 0.72363281 |
134 | MP0001881_abnormal_mammary_gland | 0.72156493 |
135 | MP0001800_abnormal_humoral_immune | 0.71630568 |
136 | MP0005666_abnormal_adipose_tissue | 0.71533070 |
137 | MP0000428_abnormal_craniofacial_morphol | 0.70749841 |
138 | MP0010678_abnormal_skin_adnexa | 0.68995304 |
139 | MP0005387_immune_system_phenotype | 0.68234133 |
140 | MP0001790_abnormal_immune_system | 0.68234133 |
141 | MP0004484_altered_response_of | 0.68071589 |
142 | MP0000685_abnormal_immune_system | 0.67912216 |
143 | MP0000313_abnormal_cell_death | 0.67496441 |
144 | MP0010234_abnormal_vibrissa_follicle | 0.67246021 |
145 | MP0002116_abnormal_craniofacial_bone | 0.66960787 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Increased density of long bones (HP:0006392) | 3.38297389 |
2 | Insomnia (HP:0100785) | 2.86360767 |
3 | Persistence of primary teeth (HP:0006335) | 2.79573321 |
4 | Broad face (HP:0000283) | 2.73445556 |
5 | Adactyly (HP:0009776) | 2.67413714 |
6 | Fragile skin (HP:0001030) | 2.66768389 |
7 | Shallow orbits (HP:0000586) | 2.51772832 |
8 | Absent hand (HP:0004050) | 2.51353988 |
9 | Epiphyseal dysplasia (HP:0002656) | 2.51210354 |
10 | Onycholysis (HP:0001806) | 2.47282801 |
11 | Advanced eruption of teeth (HP:0006288) | 2.41394745 |
12 | Subacute progressive viral hepatitis (HP:0006572) | 2.38593595 |
13 | Upper limb muscle weakness (HP:0003484) | 2.34904900 |
14 | Natal tooth (HP:0000695) | 2.33255517 |
15 | Fragile nails (HP:0001808) | 2.31970268 |
16 | Long palpebral fissure (HP:0000637) | 2.31494851 |
17 | Abnormality of nail color (HP:0100643) | 2.28938148 |
18 | Hand muscle atrophy (HP:0009130) | 2.28316174 |
19 | Asymmetry of the thorax (HP:0001555) | 2.26280696 |
20 | Skull defect (HP:0001362) | 2.26064797 |
21 | Deviation of the thumb (HP:0009603) | 2.23038060 |
22 | Trismus (HP:0000211) | 2.19407880 |
23 | Increased nuchal translucency (HP:0010880) | 2.16709474 |
24 | Upper limb amyotrophy (HP:0009129) | 2.16071649 |
25 | Distal upper limb amyotrophy (HP:0007149) | 2.16071649 |
26 | Septate vagina (HP:0001153) | 2.15866664 |
27 | Osteolytic defects of the hand bones (HP:0009699) | 2.15195438 |
28 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.15195438 |
29 | Dysmetric saccades (HP:0000641) | 2.14903076 |
30 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.14025524 |
31 | Disproportionate tall stature (HP:0001519) | 2.13801725 |
32 | Hypoplastic ischia (HP:0003175) | 2.13627204 |
33 | Achilles tendon contracture (HP:0001771) | 2.12337669 |
34 | Short nail (HP:0001799) | 2.10664534 |
35 | Pterygium (HP:0001059) | 2.10619208 |
36 | Ridged nail (HP:0001807) | 2.08458365 |
37 | Hyperacusis (HP:0010780) | 2.08147964 |
38 | Proximal placement of thumb (HP:0009623) | 2.07569213 |
39 | Cerebral aneurysm (HP:0004944) | 2.07330227 |
40 | Sparse lateral eyebrow (HP:0005338) | 2.04764883 |
41 | Insidious onset (HP:0003587) | 2.01439474 |
42 | Termporal pattern (HP:0011008) | 2.01439474 |
43 | Glossoptosis (HP:0000162) | 1.99625260 |
44 | Urethral obstruction (HP:0000796) | 1.98354651 |
45 | Spinal cord lesions (HP:0100561) | 1.98167993 |
46 | Syringomyelia (HP:0003396) | 1.98167993 |
47 | Right ventricular cardiomyopathy (HP:0011663) | 1.96557093 |
48 | Distal lower limb amyotrophy (HP:0008944) | 1.94501326 |
49 | Overriding aorta (HP:0002623) | 1.93196199 |
50 | Ankle contracture (HP:0006466) | 1.92176141 |
51 | Vertebral compression fractures (HP:0002953) | 1.91798413 |
52 | Small epiphyses (HP:0010585) | 1.91500995 |
53 | Premature rupture of membranes (HP:0001788) | 1.91365431 |
54 | Plantar hyperkeratosis (HP:0007556) | 1.88371915 |
55 | Abnormality of the umbilical cord (HP:0010881) | 1.88287787 |
56 | Nail dystrophy (HP:0008404) | 1.88254701 |
57 | Aortic aneurysm (HP:0004942) | 1.86356993 |
58 | Biconcave vertebral bodies (HP:0004586) | 1.86158664 |
59 | Protrusio acetabuli (HP:0003179) | 1.85585032 |
60 | Arterial tortuosity (HP:0005116) | 1.85303009 |
61 | Abnormality of oral frenula (HP:0000190) | 1.84311903 |
62 | Patellar dislocation (HP:0002999) | 1.84305869 |
63 | Absent eyelashes (HP:0000561) | 1.83200926 |
64 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.82628481 |
65 | Abnormality of the Achilles tendon (HP:0005109) | 1.81686605 |
66 | Spinal rigidity (HP:0003306) | 1.81308467 |
67 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.80450793 |
68 | Absent frontal sinuses (HP:0002688) | 1.80264708 |
69 | Abnormal ossification of hand bones (HP:0005921) | 1.79782332 |
70 | IgA deficiency (HP:0002720) | 1.78795125 |
71 | Elbow flexion contracture (HP:0002987) | 1.78496316 |
72 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.78017321 |
73 | Macroorchidism (HP:0000053) | 1.77937465 |
74 | Abnormal vertebral ossification (HP:0100569) | 1.77643545 |
75 | Abnormality of carpal bone ossification (HP:0006257) | 1.77295396 |
76 | Vascular tortuosity (HP:0004948) | 1.77116422 |
77 | Somatic mutation (HP:0001428) | 1.76146027 |
78 | Back pain (HP:0003418) | 1.75924040 |
79 | Progressive muscle weakness (HP:0003323) | 1.75664048 |
80 | Ankyloglossia (HP:0010296) | 1.74416277 |
81 | Arnold-Chiari malformation (HP:0002308) | 1.74182818 |
82 | Missing ribs (HP:0000921) | 1.73669443 |
83 | Abnormality of the ischium (HP:0003174) | 1.73524342 |
84 | Aplasia cutis congenita (HP:0001057) | 1.73441870 |
85 | Obstructive sleep apnea (HP:0002870) | 1.73282417 |
86 | Heterotopia (HP:0002282) | 1.73216520 |
87 | Chromsome breakage (HP:0040012) | 1.72569183 |
88 | Relative macrocephaly (HP:0004482) | 1.72179707 |
89 | Mitral regurgitation (HP:0001653) | 1.72049494 |
90 | Abnormality of the salivary glands (HP:0010286) | 1.71569367 |
91 | Lower limb amyotrophy (HP:0007210) | 1.71483955 |
92 | Blue sclerae (HP:0000592) | 1.69795011 |
93 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.69563378 |
94 | Deep philtrum (HP:0002002) | 1.69554085 |
95 | Porencephaly (HP:0002132) | 1.68859241 |
96 | Cervical subluxation (HP:0003308) | 1.67059752 |
97 | Flat acetabular roof (HP:0003180) | 1.64727839 |
98 | Abnormality of the calcaneus (HP:0008364) | 1.64320125 |
99 | Spinal cord compression (HP:0002176) | 1.63868378 |
100 | Breast hypoplasia (HP:0003187) | 1.63500301 |
101 | Smooth philtrum (HP:0000319) | 1.63037009 |
102 | Thoracolumbar scoliosis (HP:0002944) | 1.62857398 |
103 | Bowel diverticulosis (HP:0005222) | 1.62732932 |
104 | Genu recurvatum (HP:0002816) | 1.62569306 |
105 | Fatigue (HP:0012378) | 1.62071791 |
106 | Aortic dissection (HP:0002647) | 1.60997144 |
107 | Bicuspid aortic valve (HP:0001647) | 1.60806265 |
108 | Milia (HP:0001056) | 1.60256806 |
109 | Short 4th metacarpal (HP:0010044) | 1.59605082 |
110 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.59605082 |
111 | Overlapping toe (HP:0001845) | 1.59602188 |
112 | Alopecia of scalp (HP:0002293) | 1.59266114 |
113 | Abnormality of the fingertips (HP:0001211) | 1.59118415 |
114 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.59043260 |
115 | Pili torti (HP:0003777) | 1.58906050 |
116 | Abnormality of the peritoneum (HP:0002585) | 1.57836634 |
117 | Hypoplastic toenails (HP:0001800) | 1.57753713 |
118 | Vertebral arch anomaly (HP:0008438) | 1.56759679 |
119 | Limited elbow extension (HP:0001377) | 1.56127755 |
120 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.55577284 |
121 | Selective tooth agenesis (HP:0001592) | 1.53879842 |
122 | Ulnar bowing (HP:0003031) | 1.53507471 |
123 | Uterine leiomyosarcoma (HP:0002891) | 1.53148318 |
124 | Leiomyosarcoma (HP:0100243) | 1.53148318 |
125 | Thrombocytosis (HP:0001894) | 1.52307414 |
126 | Wormian bones (HP:0002645) | 1.51817973 |
127 | Astrocytoma (HP:0009592) | 1.51736069 |
128 | Abnormality of the astrocytes (HP:0100707) | 1.51736069 |
129 | Mitral valve prolapse (HP:0001634) | 1.51239481 |
130 | Dilatation of the ascending aorta (HP:0005111) | 1.51117073 |
131 | Gastrointestinal carcinoma (HP:0002672) | 1.50996707 |
132 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.50996707 |
133 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.50123732 |
134 | Amaurosis fugax (HP:0100576) | 1.49427090 |
135 | Broad palm (HP:0001169) | 1.48506150 |
136 | Metaphyseal cupping (HP:0003021) | 1.47687021 |
137 | Atrophic scars (HP:0001075) | 1.47550434 |
138 | Radial bowing (HP:0002986) | 1.46428879 |
139 | Bladder diverticulum (HP:0000015) | 1.46365406 |
140 | Vertebral hypoplasia (HP:0008417) | 1.45608548 |
141 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.45608548 |
142 | Esophageal atresia (HP:0002032) | 1.44815756 |
143 | Elfin facies (HP:0004428) | 1.44736856 |
144 | Severe short stature (HP:0003510) | 1.44675796 |
145 | Mild short stature (HP:0003502) | 1.44407201 |
146 | Chin dimple (HP:0010751) | 1.43306337 |
147 | Hypoplasia of the iris (HP:0007676) | 1.42976883 |
148 | 11 pairs of ribs (HP:0000878) | 1.41494062 |
149 | Cutis marmorata (HP:0000965) | 1.40480028 |
150 | Difficulty climbing stairs (HP:0003551) | 1.40453073 |
151 | Abnormality of the right ventricle (HP:0001707) | 1.39624012 |
152 | Bladder carcinoma (HP:0002862) | 1.38587946 |
153 | Bladder neoplasm (HP:0009725) | 1.38587946 |
154 | Ependymoma (HP:0002888) | 1.37820063 |
155 | Thick nail (HP:0001805) | 1.37794151 |
156 | Basal cell carcinoma (HP:0002671) | 1.37668604 |
157 | Renal duplication (HP:0000075) | 1.37498044 |
158 | Ureteral stenosis (HP:0000071) | 1.36648395 |
159 | Irregular epiphyses (HP:0010582) | 1.36027571 |
160 | Abnormality of the gastric mucosa (HP:0004295) | 1.35903341 |
161 | Long eyelashes (HP:0000527) | 1.35885297 |
162 | Supernumerary ribs (HP:0005815) | 1.35854758 |
163 | Stomatitis (HP:0010280) | 1.35782597 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EEF2K | 4.68995954 |
2 | CDK12 | 4.37724000 |
3 | SMG1 | 3.89250083 |
4 | IRAK3 | 3.15238839 |
5 | PKN2 | 2.53975465 |
6 | MAP4K1 | 2.50787468 |
7 | TRIB3 | 2.43813077 |
8 | MST1R | 2.38347198 |
9 | PRPF4B | 2.36401720 |
10 | LATS2 | 2.07217010 |
11 | BRD4 | 1.99023466 |
12 | ALK | 1.88579864 |
13 | MAP3K10 | 1.87933653 |
14 | KDR | 1.85098179 |
15 | EPHA2 | 1.78856287 |
16 | MST4 | 1.76164681 |
17 | TAOK1 | 1.71657687 |
18 | TTN | 1.62989877 |
19 | RPS6KB2 | 1.62787217 |
20 | LMTK2 | 1.59319441 |
21 | JAK3 | 1.56858330 |
22 | SIK2 | 1.52984635 |
23 | SCYL2 | 1.48837766 |
24 | PAK2 | 1.48696584 |
25 | STK10 | 1.48258117 |
26 | BMX | 1.47658635 |
27 | DMPK | 1.45778112 |
28 | MTOR | 1.43015728 |
29 | MET | 1.39630879 |
30 | TAF1 | 1.38545680 |
31 | TSSK6 | 1.37012520 |
32 | CAMK1D | 1.36061654 |
33 | LRRK2 | 1.35439321 |
34 | PIM2 | 1.35268628 |
35 | PRKD3 | 1.28453621 |
36 | ERN1 | 1.26676427 |
37 | ZAP70 | 1.25988385 |
38 | TYRO3 | 1.25751288 |
39 | CHUK | 1.24965754 |
40 | PDGFRA | 1.22786137 |
41 | TTK | 1.22648524 |
42 | FGFR4 | 1.22478198 |
43 | NME2 | 1.21382263 |
44 | CDC7 | 1.17856036 |
45 | PTK6 | 1.16594554 |
46 | LATS1 | 1.14946712 |
47 | PASK | 1.13157447 |
48 | ITK | 1.12785476 |
49 | MAP3K9 | 1.12327347 |
50 | NTRK1 | 1.09997985 |
51 | AKT3 | 1.09934446 |
52 | EIF2AK1 | 1.09500399 |
53 | BUB1 | 1.06384163 |
54 | TGFBR1 | 1.04288235 |
55 | MAP3K3 | 1.04016653 |
56 | STK3 | 1.03054862 |
57 | DDR2 | 0.99788910 |
58 | NEK2 | 0.96072287 |
59 | EPHB1 | 0.95099501 |
60 | PDGFRB | 0.94490700 |
61 | MARK3 | 0.91768060 |
62 | SIK3 | 0.91078136 |
63 | ICK | 0.89169554 |
64 | TRPM7 | 0.89092653 |
65 | CHEK1 | 0.88685079 |
66 | PIM1 | 0.88484146 |
67 | MAP3K11 | 0.86720933 |
68 | TXK | 0.86313411 |
69 | ARAF | 0.85370114 |
70 | MAP3K8 | 0.84714024 |
71 | RPS6KA4 | 0.83295307 |
72 | CHEK2 | 0.83021187 |
73 | CDK4 | 0.82420819 |
74 | CDK7 | 0.82094162 |
75 | MELK | 0.80933472 |
76 | TIE1 | 0.80913556 |
77 | CDK8 | 0.80747748 |
78 | CDK9 | 0.79884002 |
79 | MARK2 | 0.79660992 |
80 | ERBB4 | 0.76786062 |
81 | WNK1 | 0.74797733 |
82 | MAP3K14 | 0.73303359 |
83 | NUAK1 | 0.72706077 |
84 | HCK | 0.71199097 |
85 | EPHA3 | 0.70124478 |
86 | CDK6 | 0.69859651 |
87 | STK24 | 0.69453602 |
88 | MAP3K13 | 0.68641792 |
89 | PRKG2 | 0.67226683 |
90 | INSR | 0.66291692 |
91 | VRK2 | 0.66059675 |
92 | MAPKAPK3 | 0.65220402 |
93 | FGR | 0.65034853 |
94 | EGFR | 0.63550221 |
95 | CSK | 0.63289666 |
96 | IRAK2 | 0.63224218 |
97 | KSR2 | 0.63114548 |
98 | CDC42BPA | 0.62229901 |
99 | MAP2K3 | 0.62017345 |
100 | PTK2B | 0.61586668 |
101 | PAK4 | 0.61023168 |
102 | RET | 0.60978856 |
103 | SRPK1 | 0.60577509 |
104 | NLK | 0.60140294 |
105 | SIK1 | 0.59843210 |
106 | RIPK1 | 0.58967838 |
107 | MAPK11 | 0.58645573 |
108 | NEK1 | 0.58434308 |
109 | NEK9 | 0.56865098 |
110 | CSNK1D | 0.56267622 |
111 | ATM | 0.55570262 |
112 | NTRK2 | 0.55500927 |
113 | ROCK2 | 0.55449622 |
114 | CLK1 | 0.54561545 |
115 | RPS6KA2 | 0.54300675 |
116 | CAMK1G | 0.53865828 |
117 | FGFR3 | 0.53659577 |
118 | BRAF | 0.53560454 |
119 | PTK2 | 0.53311940 |
120 | PRKD2 | 0.52770903 |
121 | AURKB | 0.52597632 |
122 | WEE1 | 0.52305525 |
123 | IKBKB | 0.51821292 |
124 | PNCK | 0.50827948 |
125 | MAPKAPK2 | 0.48431234 |
126 | CDK2 | 0.48177819 |
127 | RPS6KA1 | 0.47663621 |
128 | TEC | 0.47144918 |
129 | MAP2K2 | 0.47131401 |
130 | AKT2 | 0.46689898 |
131 | HIPK2 | 0.46396070 |
132 | LCK | 0.45929974 |
133 | CSNK1A1L | 0.45855711 |
134 | GSK3A | 0.45370372 |
135 | AURKA | 0.44690740 |
136 | BRSK1 | 0.44324110 |
137 | FGFR1 | 0.43341000 |
138 | TAOK2 | 0.43311183 |
139 | EPHB2 | 0.43114517 |
140 | MOS | 0.42365129 |
141 | ATR | 0.41943674 |
142 | EIF2AK2 | 0.39390128 |
143 | CDK1 | 0.38638075 |
144 | TESK1 | 0.38361127 |
145 | ILK | 0.37298369 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 2.25480873 |
2 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.77347869 |
3 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.67527709 |
4 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.55169309 |
5 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.51784852 |
6 | Adherens junction_Homo sapiens_hsa04520 | 1.45050507 |
7 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.39556888 |
8 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.36118544 |
9 | Viral myocarditis_Homo sapiens_hsa05416 | 1.32488691 |
10 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.30210673 |
11 | * MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.29962594 |
12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.29405370 |
13 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.29126255 |
14 | Focal adhesion_Homo sapiens_hsa04510 | 1.28173578 |
15 | Prion diseases_Homo sapiens_hsa05020 | 1.22552241 |
16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.21735072 |
17 | HTLV-I infection_Homo sapiens_hsa05166 | 1.21696741 |
18 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.21441699 |
19 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.21007907 |
20 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.20528982 |
21 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.18468803 |
22 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.17236887 |
23 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.13317010 |
24 | Colorectal cancer_Homo sapiens_hsa05210 | 1.12940020 |
25 | Prostate cancer_Homo sapiens_hsa05215 | 1.12574830 |
26 | RNA transport_Homo sapiens_hsa03013 | 1.12565195 |
27 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.12137988 |
28 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.12082138 |
29 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.11464686 |
30 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.11360868 |
31 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.11146834 |
32 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.09620400 |
33 | Lysine degradation_Homo sapiens_hsa00310 | 1.09611001 |
34 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.09580634 |
35 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.07365253 |
36 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.06319250 |
37 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.04888431 |
38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.04545093 |
39 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.04298356 |
40 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.04099691 |
41 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.03509550 |
42 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.03121015 |
43 | Hepatitis B_Homo sapiens_hsa05161 | 1.03080388 |
44 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.99927785 |
45 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.99892902 |
46 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.99600954 |
47 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.97920523 |
48 | Mismatch repair_Homo sapiens_hsa03430 | 0.97843236 |
49 | Cell cycle_Homo sapiens_hsa04110 | 0.97370597 |
50 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.96905055 |
51 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.96511488 |
52 | Measles_Homo sapiens_hsa05162 | 0.95979699 |
53 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.95904332 |
54 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.95727326 |
55 | Glioma_Homo sapiens_hsa05214 | 0.95419039 |
56 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.95364986 |
57 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.94923757 |
58 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.94496081 |
59 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.94364418 |
60 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.93975122 |
61 | Base excision repair_Homo sapiens_hsa03410 | 0.93730821 |
62 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.93672700 |
63 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.92240915 |
64 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.91226000 |
65 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.91094235 |
66 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90891304 |
67 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.90663445 |
68 | Endometrial cancer_Homo sapiens_hsa05213 | 0.90378132 |
69 | Apoptosis_Homo sapiens_hsa04210 | 0.89912220 |
70 | Spliceosome_Homo sapiens_hsa03040 | 0.89598825 |
71 | Pathways in cancer_Homo sapiens_hsa05200 | 0.89354143 |
72 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.87580185 |
73 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.87244680 |
74 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.86681482 |
75 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.85955432 |
76 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.84426644 |
77 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.83016579 |
78 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.82683353 |
79 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.82089315 |
80 | Shigellosis_Homo sapiens_hsa05131 | 0.81902331 |
81 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.81880705 |
82 | Bladder cancer_Homo sapiens_hsa05219 | 0.81715677 |
83 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.81450301 |
84 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.81303277 |
85 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.81087577 |
86 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.80620097 |
87 | Leishmaniasis_Homo sapiens_hsa05140 | 0.80267104 |
88 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.78161321 |
89 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.78060581 |
90 | Thyroid cancer_Homo sapiens_hsa05216 | 0.77696940 |
91 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.77504124 |
92 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.77323275 |
93 | Amoebiasis_Homo sapiens_hsa05146 | 0.76887255 |
94 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.74820212 |
95 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.74757384 |
96 | Axon guidance_Homo sapiens_hsa04360 | 0.74739501 |
97 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.73699300 |
98 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.72849591 |
99 | Platelet activation_Homo sapiens_hsa04611 | 0.72342243 |
100 | Tight junction_Homo sapiens_hsa04530 | 0.71583316 |
101 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.71479559 |
102 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.70843422 |
103 | Galactose metabolism_Homo sapiens_hsa00052 | 0.70681146 |
104 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.70616146 |
105 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.70310403 |
106 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.70087621 |
107 | Melanoma_Homo sapiens_hsa05218 | 0.69287158 |
108 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.69220376 |
109 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.68739622 |
110 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.68635659 |
111 | Allograft rejection_Homo sapiens_hsa05330 | 0.68344319 |
112 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.68047409 |
113 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.67557513 |
114 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.65780329 |
115 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.65296770 |
116 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.64795934 |
117 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.64166737 |
118 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.64093446 |
119 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.63531444 |
120 | Insulin resistance_Homo sapiens_hsa04931 | 0.63079297 |
121 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.62999379 |
122 | Hepatitis C_Homo sapiens_hsa05160 | 0.62285789 |
123 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60969425 |
124 | Melanogenesis_Homo sapiens_hsa04916 | 0.60607350 |
125 | RNA degradation_Homo sapiens_hsa03018 | 0.60538873 |
126 | Ribosome_Homo sapiens_hsa03010 | 0.60247726 |
127 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.59804719 |
128 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.59735998 |
129 | Endocytosis_Homo sapiens_hsa04144 | 0.59561865 |
130 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.58522433 |
131 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.58483203 |
132 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.57427983 |
133 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.57293017 |
134 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.55623877 |
135 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.54792078 |
136 | Carbon metabolism_Homo sapiens_hsa01200 | 0.53532246 |
137 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.53508345 |
138 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.52528929 |
139 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.51733121 |
140 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.51139389 |
141 | Long-term potentiation_Homo sapiens_hsa04720 | 0.51121659 |
142 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.50968702 |