SLF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1histone-serine phosphorylation (GO:0035404)6.46270392
2DNA strand renaturation (GO:0000733)5.62296747
3mitotic sister chromatid cohesion (GO:0007064)5.36945896
4kinetochore organization (GO:0051383)5.33614358
5establishment of integrated proviral latency (GO:0075713)4.94685815
6regulation of histone phosphorylation (GO:0033127)4.87145079
7kinetochore assembly (GO:0051382)4.77577554
8maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.68821367
9replication fork processing (GO:0031297)4.56531653
10DNA unwinding involved in DNA replication (GO:0006268)4.37720933
11telomere maintenance via semi-conservative replication (GO:0032201)4.31380212
12meiotic chromosome segregation (GO:0045132)4.27246498
13DNA strand elongation involved in DNA replication (GO:0006271)4.15863120
14CENP-A containing nucleosome assembly (GO:0034080)4.15163047
15chromatin remodeling at centromere (GO:0031055)4.14843655
16DNA replication checkpoint (GO:0000076)4.10496558
17telomere maintenance via recombination (GO:0000722)4.09953136
18mitotic recombination (GO:0006312)4.08552541
19DNA replication initiation (GO:0006270)4.08456833
20regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.05863425
21DNA strand elongation (GO:0022616)3.99488994
22histone phosphorylation (GO:0016572)3.94278936
23nuclear pore complex assembly (GO:0051292)3.82956532
24establishment of viral latency (GO:0019043)3.78591288
25DNA replication-independent nucleosome assembly (GO:0006336)3.73494546
26DNA replication-independent nucleosome organization (GO:0034724)3.73494546
27nucleotide-excision repair, DNA gap filling (GO:0006297)3.67342229
28non-recombinational repair (GO:0000726)3.63942838
29double-strand break repair via nonhomologous end joining (GO:0006303)3.63942838
30mRNA splice site selection (GO:0006376)3.62674305
31DNA replication-dependent nucleosome assembly (GO:0006335)3.61381571
32DNA replication-dependent nucleosome organization (GO:0034723)3.61381571
33synapsis (GO:0007129)3.60289000
34regulation of meiosis I (GO:0060631)3.56416129
35mesenchymal cell differentiation involved in kidney development (GO:0072161)3.53711881
36mesenchymal cell differentiation involved in renal system development (GO:2001012)3.53711881
37protein localization to chromosome, centromeric region (GO:0071459)3.50336087
38regulation of centriole replication (GO:0046599)3.48192843
39histone exchange (GO:0043486)3.46890744
40regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.43047482
41mismatch repair (GO:0006298)3.43038484
42spindle checkpoint (GO:0031577)3.41949781
43DNA catabolic process, exonucleolytic (GO:0000738)3.40742422
44negative regulation of chromosome segregation (GO:0051985)3.36198422
45negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.35981387
46negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.35981387
47negative regulation of mitotic sister chromatid segregation (GO:0033048)3.35981387
48negative regulation of mitotic sister chromatid separation (GO:2000816)3.35981387
49negative regulation of sister chromatid segregation (GO:0033046)3.35981387
50nuclear pore organization (GO:0006999)3.32873346
51telomere maintenance via telomere lengthening (GO:0010833)3.30065804
52translesion synthesis (GO:0019985)3.29406031
53mitotic spindle checkpoint (GO:0071174)3.29268074
54mitotic chromosome condensation (GO:0007076)3.28354053
55mitotic G2/M transition checkpoint (GO:0044818)3.28092562
56attachment of spindle microtubules to kinetochore (GO:0008608)3.27993609
57regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.27600327
58sister chromatid segregation (GO:0000819)3.27433923
59presynaptic membrane assembly (GO:0097105)3.25276092
60negative regulation of fibroblast apoptotic process (GO:2000270)3.24483044
61mitotic spindle assembly checkpoint (GO:0007094)3.23663605
62mitotic nuclear envelope disassembly (GO:0007077)3.23639072
63DNA double-strand break processing (GO:0000729)3.23403071
64negative regulation of DNA recombination (GO:0045910)3.22969372
65regulation of centrosome cycle (GO:0046605)3.22183351
66sister chromatid cohesion (GO:0007062)3.21631391
67spindle assembly checkpoint (GO:0071173)3.21073544
68regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.21058834
69regulation of mitotic spindle checkpoint (GO:1903504)3.21058834
70regulation of chromosome segregation (GO:0051983)3.18592436
71recombinational repair (GO:0000725)3.15430860
72centrosome organization (GO:0051297)3.15270505
73double-strand break repair via homologous recombination (GO:0000724)3.15075944
74mitotic sister chromatid segregation (GO:0000070)3.14360954
75regulation of double-strand break repair via homologous recombination (GO:0010569)3.13304381
76protein localization to microtubule cytoskeleton (GO:0072698)3.10853987
77DNA geometric change (GO:0032392)3.10449680
78DNA duplex unwinding (GO:0032508)3.09913739
79negative regulation of DNA-dependent DNA replication (GO:2000104)3.08326211
80nucleobase biosynthetic process (GO:0046112)3.06304822
81metaphase plate congression (GO:0051310)3.05872530
82protein K6-linked ubiquitination (GO:0085020)3.05141176
83postreplication repair (GO:0006301)3.05072209
84microtubule organizing center organization (GO:0031023)3.02186441
85telomere maintenance (GO:0000723)3.01937942
86regulation of DNA endoreduplication (GO:0032875)3.01506752
87deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.00079535
88centriole assembly (GO:0098534)2.99374702
89nuclear envelope disassembly (GO:0051081)2.98595937
90membrane disassembly (GO:0030397)2.98595937
91chromosome organization involved in meiosis (GO:0070192)2.98205254
92DNA topological change (GO:0006265)2.98037907
93transcription-coupled nucleotide-excision repair (GO:0006283)2.96820612
94regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.95935588
95telomere organization (GO:0032200)2.95203726
96centrosome duplication (GO:0051298)2.95024975
97establishment of chromosome localization (GO:0051303)2.94761197
98prenylation (GO:0097354)2.93837089
99protein prenylation (GO:0018342)2.93837089
100regulation of centrosome duplication (GO:0010824)2.93562704
101regulation of nuclear cell cycle DNA replication (GO:0033262)2.93012552
102positive regulation of mitotic sister chromatid separation (GO:1901970)2.92806847
103positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.92806847
104positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.92806847
105microtubule nucleation (GO:0007020)2.89867948
106cilium or flagellum-dependent cell motility (GO:0001539)2.85453492
107ATP-dependent chromatin remodeling (GO:0043044)2.84639740
108reciprocal DNA recombination (GO:0035825)2.84341815
109intra-S DNA damage checkpoint (GO:0031573)2.83998656
110pore complex assembly (GO:0046931)2.83989673
111regulation of histone H3-K9 methylation (GO:0051570)2.82953218
112protein localization to kinetochore (GO:0034501)2.82252374
113mitotic metaphase plate congression (GO:0007080)2.81858362
114microtubule depolymerization (GO:0007019)2.81517572
1157-methylguanosine mRNA capping (GO:0006370)2.79929974
116transcription elongation from RNA polymerase I promoter (GO:0006362)2.79187939
117resolution of meiotic recombination intermediates (GO:0000712)2.75496385
1187-methylguanosine RNA capping (GO:0009452)2.75091028
119RNA capping (GO:0036260)2.75091028
120purine nucleobase biosynthetic process (GO:0009113)2.74907385
121deoxyribonucleotide biosynthetic process (GO:0009263)2.74772714
122chromatin assembly or disassembly (GO:0006333)2.74111439
123positive regulation of CREB transcription factor activity (GO:0032793)2.73027407
124pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.72407383
125glycoprotein catabolic process (GO:0006516)2.71822609
126chromosome segregation (GO:0007059)2.70931339
127centriole replication (GO:0007099)2.65816933
128positive regulation of histone H3-K4 methylation (GO:0051571)2.63488738
129somatic diversification of immune receptors via somatic mutation (GO:0002566)2.63460019
130somatic hypermutation of immunoglobulin genes (GO:0016446)2.63460019
131DNA ligation (GO:0006266)2.63036259
132regulation of sister chromatid segregation (GO:0033045)2.61858074
133regulation of mitotic sister chromatid separation (GO:0010965)2.61858074
134regulation of mitotic sister chromatid segregation (GO:0033047)2.61858074
135DNA conformation change (GO:0071103)2.61744068
136regulation of mitotic metaphase/anaphase transition (GO:0030071)2.60232252
137protein localization to cytoskeleton (GO:0044380)2.58454623
138protein-DNA complex assembly (GO:0065004)2.58131154

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse4.90637136
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.27483681
3MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.16853233
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.10631520
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.85880475
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.81323543
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.65521644
8FUS_26573619_Chip-Seq_HEK293_Human2.50690529
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.49269658
10KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.20425966
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.12989422
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.07631444
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.06936851
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.04355430
15ELK1_19687146_ChIP-ChIP_HELA_Human2.03368197
16E2F1_21310950_ChIP-Seq_MCF-7_Human2.02022832
17E2F7_22180533_ChIP-Seq_HELA_Human10.7004427
18POU3F2_20337985_ChIP-ChIP_501MEL_Human1.94098603
19TAF15_26573619_Chip-Seq_HEK293_Human1.91669190
20EWS_26573619_Chip-Seq_HEK293_Human1.88612559
21YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.79123982
22IGF1R_20145208_ChIP-Seq_DFB_Human1.76770427
23PCGF2_27294783_Chip-Seq_ESCs_Mouse1.72471331
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64501749
25MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.64475462
26MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.64308950
27FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64112820
28VDR_22108803_ChIP-Seq_LS180_Human1.63582287
29CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.59808859
30BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.59176223
31EST1_17652178_ChIP-ChIP_JURKAT_Human1.58098054
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54536278
33MYC_19030024_ChIP-ChIP_MESCs_Mouse1.53734072
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.52803239
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.50027036
36CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.48045512
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.47882384
38GBX2_23144817_ChIP-Seq_PC3_Human1.47653287
39CREB1_15753290_ChIP-ChIP_HEK293T_Human1.45072551
40PADI4_21655091_ChIP-ChIP_MCF-7_Human1.44464985
41VDR_23849224_ChIP-Seq_CD4+_Human1.43593583
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.39525258
43FOXP3_21729870_ChIP-Seq_TREG_Human1.38985850
44SMAD_19615063_ChIP-ChIP_OVARY_Human1.36926868
45NOTCH1_21737748_ChIP-Seq_TLL_Human1.35956245
46ZNF274_21170338_ChIP-Seq_K562_Hela1.35950074
47MYC_18940864_ChIP-ChIP_HL60_Human1.31020543
48GABP_17652178_ChIP-ChIP_JURKAT_Human1.30692269
49AR_21909140_ChIP-Seq_LNCAP_Human1.29731868
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.26692701
51CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.24121872
52NELFA_20434984_ChIP-Seq_ESCs_Mouse1.24065840
53IRF1_19129219_ChIP-ChIP_H3396_Human1.22939993
54MYC_19079543_ChIP-ChIP_MESCs_Mouse1.20670843
55E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.18468831
56PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16889699
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.15117178
58SOX9_26525672_Chip-Seq_HEART_Mouse1.12356395
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.12292191
60SOX2_18555785_ChIP-Seq_MESCs_Mouse1.12247498
61MYC_18358816_ChIP-ChIP_MESCs_Mouse1.11874625
62TP63_19390658_ChIP-ChIP_HaCaT_Human1.11671783
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11447912
64JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.11353736
65NANOG_18555785_Chip-Seq_ESCs_Mouse1.10757030
66TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10480247
67POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.10031884
68EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.07275898
69SUZ12_18555785_Chip-Seq_ESCs_Mouse1.07216952
70P300_19829295_ChIP-Seq_ESCs_Human1.06806540
71E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05413887
72MYCN_18555785_ChIP-Seq_MESCs_Mouse1.05182397
73GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.03686191
74E2F1_18555785_Chip-Seq_ESCs_Mouse1.03395398
75P53_22387025_ChIP-Seq_ESCs_Mouse1.03353909
76SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.02418322
77ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02180050
78ETS1_20019798_ChIP-Seq_JURKAT_Human1.01695808
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01540885
80NANOG_16153702_ChIP-ChIP_HESCs_Human1.01437501
81PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99846565
82ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.98785793
83NFE2_27457419_Chip-Seq_LIVER_Mouse0.97300822
84TTF2_22483619_ChIP-Seq_HELA_Human0.97251544
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96077176
86RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95346910
87SUZ12_27294783_Chip-Seq_NPCs_Mouse0.95006654
88RNF2_27304074_Chip-Seq_NSC_Mouse0.93814099
89CMYC_18555785_Chip-Seq_ESCs_Mouse0.93294892
90HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.92747388
91PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.92428360
92XRN2_22483619_ChIP-Seq_HELA_Human0.92068517
93TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92007050
94RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.91985171
95EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.91434794
96RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.90993127
97SRF_21415370_ChIP-Seq_HL-1_Mouse0.90710453
98STAT3_18555785_Chip-Seq_ESCs_Mouse0.90622324
99OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90495919
100AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.89315762
101GABP_19822575_ChIP-Seq_HepG2_Human0.89174616
102POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.89000779
103CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88715667
104TP53_22573176_ChIP-Seq_HFKS_Human0.88502823
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87669251
106P300_18555785_Chip-Seq_ESCs_Mouse0.87021421
107EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.86496429
108E2F1_18555785_ChIP-Seq_MESCs_Mouse0.86249983
109MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.85688709
110NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.84724241
111ELF1_17652178_ChIP-ChIP_JURKAT_Human0.84101693
112SMAD3_21741376_ChIP-Seq_EPCs_Human0.83881863
113TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.83765398
114SOX2_16153702_ChIP-ChIP_HESCs_Human0.83575744
115CTBP1_25329375_ChIP-Seq_LNCAP_Human0.82443980
116ER_23166858_ChIP-Seq_MCF-7_Human0.82205145
117DCP1A_22483619_ChIP-Seq_HELA_Human0.81353129
118CTBP2_25329375_ChIP-Seq_LNCAP_Human0.80895528
119EZH2_27294783_Chip-Seq_NPCs_Mouse0.80864623
120CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.80433280
121KDM5A_27292631_Chip-Seq_BREAST_Human0.80283163
122NMYC_18555785_Chip-Seq_ESCs_Mouse0.80246919
123SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.77743054
124GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.77405864
125GATA1_26923725_Chip-Seq_HPCs_Mouse0.77243431

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.39163253
2MP0008057_abnormal_DNA_replication3.37679140
3MP0001986_abnormal_taste_sensitivity2.97829143
4MP0003077_abnormal_cell_cycle2.94324691
5MP0008058_abnormal_DNA_repair2.90932225
6MP0003693_abnormal_embryo_hatching2.81999335
7MP0003111_abnormal_nucleus_morphology2.73293840
8MP0006292_abnormal_olfactory_placode2.52954050
9MP0008877_abnormal_DNA_methylation2.48485260
10MP0003121_genomic_imprinting2.43149388
11MP0004808_abnormal_hematopoietic_stem2.42879683
12MP0004957_abnormal_blastocyst_morpholog2.30507596
13MP0003787_abnormal_imprinting2.28965565
14MP0003718_maternal_effect2.27538862
15MP0003136_yellow_coat_color2.10995282
16MP0005423_abnormal_somatic_nervous2.08704394
17MP0003123_paternal_imprinting2.03995691
18MP0002102_abnormal_ear_morphology1.95278251
19MP0001188_hyperpigmentation1.88731512
20MP0008932_abnormal_embryonic_tissue1.87336454
21MP0002396_abnormal_hematopoietic_system1.79435959
22MP0005083_abnormal_biliary_tract1.79042991
23MP0001529_abnormal_vocalization1.75366798
24MP0010307_abnormal_tumor_latency1.74286851
25MP0010030_abnormal_orbit_morphology1.74260030
26MP0008789_abnormal_olfactory_epithelium1.70851639
27MP0003943_abnormal_hepatobiliary_system1.69702345
28MP0002938_white_spotting1.53694910
29MP0001286_abnormal_eye_development1.53362987
30MP0002697_abnormal_eye_size1.49782210
31MP0003786_premature_aging1.49382686
32MP0002210_abnormal_sex_determination1.48887067
33MP0002233_abnormal_nose_morphology1.37610387
34MP0008007_abnormal_cellular_replicative1.37607526
35MP0005646_abnormal_pituitary_gland1.37473410
36MP0003890_abnormal_embryonic-extraembry1.37387441
37MP0005253_abnormal_eye_physiology1.36788605
38MP0003283_abnormal_digestive_organ1.35762062
39MP0003122_maternal_imprinting1.32727292
40MP0003880_abnormal_central_pattern1.32409458
41MP0000778_abnormal_nervous_system1.32028270
42MP0000350_abnormal_cell_proliferation1.28387536
43MP0001929_abnormal_gametogenesis1.25123393
44MP0002095_abnormal_skin_pigmentation1.21844291
45MP0001145_abnormal_male_reproductive1.16814526
46MP0004215_abnormal_myocardial_fiber1.13655997
47MP0000681_abnormal_thyroid_gland1.12171520
48MP0006035_abnormal_mitochondrial_morpho1.11556377
49MP0003567_abnormal_fetal_cardiomyocyte1.11469741
50MP0003698_abnormal_male_reproductive1.11276070
51MP0005409_darkened_coat_color1.11045763
52MP0005551_abnormal_eye_electrophysiolog1.10031683
53MP0001730_embryonic_growth_arrest1.09109587
54MP0000653_abnormal_sex_gland1.06566268
55MP0002084_abnormal_developmental_patter1.05998488
56MP0002736_abnormal_nociception_after1.04963156
57MP0005075_abnormal_melanosome_morpholog1.03570608
58MP0002085_abnormal_embryonic_tissue1.01781748
59MP0001697_abnormal_embryo_size1.01611697
60MP0005391_vision/eye_phenotype1.01174309
61MP0003755_abnormal_palate_morphology1.00858789
62MP0005645_abnormal_hypothalamus_physiol0.99788400
63MP0000631_abnormal_neuroendocrine_gland0.99643688
64MP0003937_abnormal_limbs/digits/tail_de0.98358991
65MP0000703_abnormal_thymus_morphology0.97322395
66MP0000015_abnormal_ear_pigmentation0.97307303
67MP0001293_anophthalmia0.96929179
68MP0002160_abnormal_reproductive_system0.96864957
69MP0010234_abnormal_vibrissa_follicle0.96782174
70MP0002111_abnormal_tail_morphology0.96764040
71MP0001672_abnormal_embryogenesis/_devel0.95369060
72MP0005380_embryogenesis_phenotype0.95369060
73MP0001968_abnormal_touch/_nociception0.95222323
74MP0009697_abnormal_copulation0.95196317
75MP0003119_abnormal_digestive_system0.94336664
76MP0009745_abnormal_behavioral_response0.94231443
77MP0000313_abnormal_cell_death0.93801483
78MP0008995_early_reproductive_senescence0.93751036
79MP0004924_abnormal_behavior0.93592046
80MP0005386_behavior/neurological_phenoty0.93592046
81MP0002751_abnormal_autonomic_nervous0.93517142
82MP0005389_reproductive_system_phenotype0.92314895
83MP0002234_abnormal_pharynx_morphology0.92149917
84MP0005171_absent_coat_pigmentation0.92112252
85MP0000647_abnormal_sebaceous_gland0.91521820
86MP0001177_atelectasis0.91378566
87MP0004133_heterotaxia0.90270746
88MP0006072_abnormal_retinal_apoptosis0.90246314
89MP0000049_abnormal_middle_ear0.90057593
90MP0005174_abnormal_tail_pigmentation0.89035905
91MP0001919_abnormal_reproductive_system0.85388516
92MP0003861_abnormal_nervous_system0.84517517
93MP0001346_abnormal_lacrimal_gland0.83536992
94MP0000490_abnormal_crypts_of0.83028985
95MP0003699_abnormal_female_reproductive0.82466268
96MP0002009_preneoplasia0.81963086
97MP0009703_decreased_birth_body0.81632682
98MP0003938_abnormal_ear_development0.81557969
99MP0003935_abnormal_craniofacial_develop0.81524423
100MP0001324_abnormal_eye_pigmentation0.78721164
101MP0000428_abnormal_craniofacial_morphol0.78585939
102MP0002088_abnormal_embryonic_growth/wei0.78184108
103MP0003385_abnormal_body_wall0.78031753
104MP0002081_perinatal_lethality0.77980026
105MP0005195_abnormal_posterior_eye0.77878825
106MP0002080_prenatal_lethality0.77593631
107MP0000372_irregular_coat_pigmentation0.77210855
108MP0002063_abnormal_learning/memory/cond0.76920807
109MP0005395_other_phenotype0.76486091
110MP0002398_abnormal_bone_marrow0.75403610
111MP0004134_abnormal_chest_morphology0.75152872
112MP0001119_abnormal_female_reproductive0.74876520
113MP0003941_abnormal_skin_development0.74704102
114MP0003984_embryonic_growth_retardation0.74695320
115MP0001485_abnormal_pinna_reflex0.73479661
116MP0005187_abnormal_penis_morphology0.73435327
117MP0005397_hematopoietic_system_phenotyp0.72917583
118MP0001545_abnormal_hematopoietic_system0.72917583
119MP0002019_abnormal_tumor_incidence0.72440682
120MP0004147_increased_porphyrin_level0.72166002
121MP0006054_spinal_hemorrhage0.72071121
122MP0002086_abnormal_extraembryonic_tissu0.71546942
123MP0002114_abnormal_axial_skeleton0.70705799
124MP0002735_abnormal_chemical_nociception0.69751291
125MP0002282_abnormal_trachea_morphology0.69727033
126MP0002109_abnormal_limb_morphology0.69074133
127MP0005499_abnormal_olfactory_system0.68759256
128MP0005394_taste/olfaction_phenotype0.68759256
129MP0000569_abnormal_digit_pigmentation0.68361622
130MP0002067_abnormal_sensory_capabilities0.68312977
131MP0004197_abnormal_fetal_growth/weight/0.67911996
132MP0003763_abnormal_thymus_physiology0.67206754
133MP0000427_abnormal_hair_cycle0.66911485
134MP0002177_abnormal_outer_ear0.63729096
135MP0002161_abnormal_fertility/fecundity0.63310042

Predicted human phenotypes

RankGene SetZ-score
1Asymmetry of the thorax (HP:0001555)4.64247589
2Fibular aplasia (HP:0002990)4.36424804
3Abnormality of midbrain morphology (HP:0002418)4.31527750
4Molar tooth sign on MRI (HP:0002419)4.31527750
5Chromsome breakage (HP:0040012)4.16538750
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.81919619
7Thyroid-stimulating hormone excess (HP:0002925)3.74800088
8Hypoplasia of the capital femoral epiphysis (HP:0003090)3.63364636
9Abnormality of chromosome stability (HP:0003220)3.57050682
10Oligodactyly (hands) (HP:0001180)3.41442137
11Fibular hypoplasia (HP:0003038)3.26020400
12Protruding tongue (HP:0010808)3.19701524
13True hermaphroditism (HP:0010459)3.12076692
14Papilledema (HP:0001085)3.11678338
15Birth length less than 3rd percentile (HP:0003561)2.91885674
16Pancreatic fibrosis (HP:0100732)2.90942927
17Aplasia/Hypoplasia of the fibula (HP:0006492)2.90290147
18Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.89307201
19Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.81804233
20Absent epiphyses (HP:0010577)2.76870975
21Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.76870975
22Abnormality of the duodenum (HP:0002246)2.74861859
23Abnormal lung lobation (HP:0002101)2.72415823
24Postaxial foot polydactyly (HP:0001830)2.64013605
2511 pairs of ribs (HP:0000878)2.62192651
26Aplasia involving forearm bones (HP:0009822)2.61654736
27Absent forearm bone (HP:0003953)2.61654736
28Abnormal respiratory motile cilium physiology (HP:0012261)2.61282185
29Volvulus (HP:0002580)2.59146447
30Pancreatic cysts (HP:0001737)2.56510812
31Myelodysplasia (HP:0002863)2.52138523
32Abnormal ciliary motility (HP:0012262)2.51020099
33Oligodactyly (HP:0012165)2.49976353
34Increased hepatocellular lipid droplets (HP:0006565)2.49534516
35Abnormality of the carotid arteries (HP:0005344)2.46287830
36Meckel diverticulum (HP:0002245)2.45608589
37Nephroblastoma (Wilms tumor) (HP:0002667)2.43972543
38Abnormality of the preputium (HP:0100587)2.43476358
39Aplasia/Hypoplasia of the tibia (HP:0005772)2.43327748
40Nephronophthisis (HP:0000090)2.43164482
41Abnormality of DNA repair (HP:0003254)2.42457869
42Cerebral edema (HP:0002181)2.39565734
43Cerebellar dysplasia (HP:0007033)2.39486973
44Abnormality of the ileum (HP:0001549)2.33042211
45Trigonocephaly (HP:0000243)2.31640678
46Embryonal renal neoplasm (HP:0011794)2.31421674
47Absent/shortened dynein arms (HP:0200106)2.29667088
48Dynein arm defect of respiratory motile cilia (HP:0012255)2.29667088
49Lipid accumulation in hepatocytes (HP:0006561)2.29553490
50Abnormal respiratory motile cilium morphology (HP:0005938)2.29024858
51Abnormal respiratory epithelium morphology (HP:0012253)2.29024858
52Aplasia/Hypoplasia of the uvula (HP:0010293)2.28983822
53Colon cancer (HP:0003003)2.28114583
54Thoracic kyphosis (HP:0002942)2.27931970
55High pitched voice (HP:0001620)2.27235194
56Degeneration of anterior horn cells (HP:0002398)2.24623810
57Abnormality of the anterior horn cell (HP:0006802)2.24623810
58Rhinitis (HP:0012384)2.23007361
59Occipital encephalocele (HP:0002085)2.22067225
60Acute necrotizing encephalopathy (HP:0006965)2.21103150
61Sloping forehead (HP:0000340)2.18391344
62Glioma (HP:0009733)2.14358701
63Preaxial hand polydactyly (HP:0001177)2.12835028
64Aplasia/Hypoplasia of the tongue (HP:0010295)2.12790974
65Bifid tongue (HP:0010297)2.12249799
66Abnormality of the renal collecting system (HP:0004742)2.12026593
67Short tibia (HP:0005736)2.10679658
68Intestinal atresia (HP:0011100)2.08721427
69Abnormal mitochondria in muscle tissue (HP:0008316)2.08234039
70Patellar aplasia (HP:0006443)2.08174008
71Septo-optic dysplasia (HP:0100842)2.07724416
72Abnormality of the thoracic spine (HP:0100711)2.05892819
73Clubbing of toes (HP:0100760)2.05583112
74Wrist flexion contracture (HP:0001239)2.05149317
75Partial agenesis of the corpus callosum (HP:0001338)2.03728308
76Abnormality of the heme biosynthetic pathway (HP:0010472)2.03110092
77Absent thumb (HP:0009777)2.02787545
78Tented upper lip vermilion (HP:0010804)2.02652434
79Increased CSF lactate (HP:0002490)2.02055752
80Ectopic kidney (HP:0000086)2.00835456
81Medulloblastoma (HP:0002885)2.00815245
82Duodenal stenosis (HP:0100867)1.97525554
83Small intestinal stenosis (HP:0012848)1.97525554
84Short thumb (HP:0009778)1.95125638
85Absent septum pellucidum (HP:0001331)1.92880199
86Acute encephalopathy (HP:0006846)1.92039506
87Horseshoe kidney (HP:0000085)1.91052973
88Median cleft lip (HP:0000161)1.90780400
89Tubulointerstitial nephritis (HP:0001970)1.89604848
90Aplasia/Hypoplasia of the sacrum (HP:0008517)1.89212722
91Prominent metopic ridge (HP:0005487)1.89090736
92Increased nuchal translucency (HP:0010880)1.88731071
93Inappropriate behavior (HP:0000719)1.87832476
94Abnormality of the metopic suture (HP:0005556)1.87063517
95Supernumerary spleens (HP:0009799)1.86574323
96Anencephaly (HP:0002323)1.86337537
97Small hand (HP:0200055)1.86193500
98Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.85828079
99Tracheomalacia (HP:0002779)1.84245020
100Aplasia/Hypoplasia of the patella (HP:0006498)1.83112238
101Delayed closure of the anterior fontanelle (HP:0001476)1.83068285
102Mitochondrial inheritance (HP:0001427)1.82669857
103Gonadotropin excess (HP:0000837)1.82141634
104Natal tooth (HP:0000695)1.81596582
105Rhabdomyosarcoma (HP:0002859)1.80798165
106Abnormality of the septum pellucidum (HP:0007375)1.80746496
107Abnormality of alanine metabolism (HP:0010916)1.80410426
108Hyperalaninemia (HP:0003348)1.80410426
109Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.80410426
110Abnormality of the labia minora (HP:0012880)1.79902241
111Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.79019345
112Epileptic encephalopathy (HP:0200134)1.78914166
113Progressive macrocephaly (HP:0004481)1.78785427
114Astrocytoma (HP:0009592)1.78404963
115Abnormality of the astrocytes (HP:0100707)1.78404963
116Anal stenosis (HP:0002025)1.77062201
117Abnormal number of incisors (HP:0011064)1.77024431
118Abnormality of the pons (HP:0007361)1.75240221
119Abnormality of methionine metabolism (HP:0010901)1.74830966
120Neoplasm of the colon (HP:0100273)1.74401656
121Reticulocytopenia (HP:0001896)1.73124113
122Anophthalmia (HP:0000528)1.72852061
123Absent speech (HP:0001344)1.72705512
124Cafe-au-lait spot (HP:0000957)1.71878919
125Duplication of thumb phalanx (HP:0009942)1.71652687
126Renal Fanconi syndrome (HP:0001994)1.71372532
127Acute lymphatic leukemia (HP:0006721)1.70939283
128Aplasia/Hypoplasia of the sternum (HP:0006714)1.70772495
129Increased number of teeth (HP:0011069)1.70452188
130Duplicated collecting system (HP:0000081)1.68578014
131Absent radius (HP:0003974)1.67410537
132Oligohydramnios (HP:0001562)1.67324202
133Gastrointestinal atresia (HP:0002589)1.66856107
134Rimmed vacuoles (HP:0003805)1.66666727
135Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.66389966
136Acute myeloid leukemia (HP:0004808)1.66160142
137Astigmatism (HP:0000483)1.66034629
138Triphalangeal thumb (HP:0001199)1.65760830
139Neoplasm of the oral cavity (HP:0100649)1.65385271
140Renal cortical cysts (HP:0000803)1.65074563
141Abnormality of the renal medulla (HP:0100957)1.64758578
142Sclerocornea (HP:0000647)1.64014628
143Choanal atresia (HP:0000453)1.63790900
144Ependymoma (HP:0002888)1.62701571
145IgM deficiency (HP:0002850)1.62648437
146Clitoromegaly (HP:0000057)1.62034542
147Abnormality of the phalanges of the 5th finger (HP:0004213)1.61942345
148Stenosis of the external auditory canal (HP:0000402)1.61724189
149Hypoplasia of the pons (HP:0012110)1.61001688
150Bronchiectasis (HP:0002110)1.60512360
151Arteriovenous malformation (HP:0100026)1.60208317
152Pancreatic islet-cell hyperplasia (HP:0004510)1.60070985
153Aqueductal stenosis (HP:0002410)1.60043577
154Fair hair (HP:0002286)1.59935844
155Neurodegeneration (HP:0002180)1.56692422
156Abnormality of the phalanges of the hallux (HP:0010057)1.56188712
157Microtia (HP:0008551)1.55155275
158Aplastic anemia (HP:0001915)1.55117783
159IgG deficiency (HP:0004315)1.53890816

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC77.25100739
2CCNB14.39912083
3WEE13.19363106
4PDK22.69597160
5CDK82.58925901
6SRPK12.52362702
7EIF2AK12.43447398
8ACVR1B2.35662799
9TRIM282.21884462
10PLK42.12017858
11PBK2.10172713
12NEK22.06464259
13CASK2.05004941
14VRK11.92919392
15STK391.91930866
16MKNK11.87251114
17BRSK21.85177261
18RPS6KA51.85028085
19WNK31.79046880
20ZAK1.76647038
21ATR1.76102105
22EPHA31.71824607
23WNK41.67408558
24NUAK11.67225805
25BUB11.64256938
26OXSR11.57308809
27VRK21.55916092
28BRSK11.55462897
29PLK31.50338896
30MAP2K71.49143267
31ERBB31.42744973
32MKNK21.38614014
33SGK21.36784056
34RPS6KA61.36703901
35EIF2AK31.32566383
36TAF11.29934912
37STK161.25079038
38CHEK21.24057499
39PLK11.23574576
40TTK1.19596933
41MAPK131.19317497
42MAP3K121.14736927
43TLK11.12761102
44YES11.12666980
45MST41.11515107
46MAP3K141.10669595
47CDK191.05835933
48PASK1.05817151
49MAP4K21.05170826
50PLK21.04607201
51FRK1.01244361
52AURKB1.01221489
53PNCK0.97103013
54CAMKK20.96292535
55ATM0.89565495
56NEK10.86833100
57MAP3K100.85818705
58CHEK10.83877678
59TNIK0.83624229
60EPHA40.82808611
61EIF2AK20.82684589
62TSSK60.81721735
63STK30.81629919
64STK40.79046940
65MARK10.78611250
66DYRK1B0.77876541
67CSNK1G10.77005076
68RPS6KB10.74050700
69NEK60.72146638
70STK38L0.70069353
71CDK70.68945603
72ADRBK20.68029009
73TEC0.65670295
74BRD40.64833427
75RPS6KA40.64559574
76MINK10.64489872
77DYRK30.64222017
78SIK20.63204822
79BRAF0.62187207
80BCR0.61907350
81DAPK10.60785501
82SGK30.60516878
83MAP3K60.59595274
84SGK2230.59443442
85SGK4940.59443442
86CDK10.58681470
87CDK30.58504340
88CDK20.58067956
89CSNK2A10.55611206
90GRK10.54906010
91MELK0.54393594
92DYRK20.54257370
93RPS6KB20.53049609
94DYRK1A0.52941164
95AKT30.52741207
96PDK30.52730592
97PDK40.52730592
98PIK3CA0.52608600
99CSNK1G30.51644750
100NME10.50956348
101CSNK1G20.50081275
102CDK90.48836451
103TGFBR10.48175543
104BMPR1B0.45996411
105CSNK1E0.45119243
106PRKDC0.44495370
107MUSK0.44447296
108BMPR20.40723645
109TRPM70.39487929
110INSRR0.39230257
111MAPKAPK50.38103591
112PIM10.38048587
113OBSCN0.37532145
114PKN10.37192989
115AURKA0.36529528
116MAP3K80.34876187
117NTRK30.34533711
118SGK10.33634881
119PRKCG0.32185351
120CSNK2A20.31692141
121ERBB40.31352087
122CSNK1A1L0.30973961
123MAP3K40.30608590
124NLK0.29374389
125FGFR10.29109612
126UHMK10.28910935
127MAPK140.28884993
128CAMK1D0.27329818
129ADRBK10.26334197
130MST1R0.26072837
131MAPK80.25995010
132GSK3B0.25987346
133MAP3K50.25878850
134LATS10.25481613
135CDK40.24828227
136STK240.22971985
137MAP2K60.22419952

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.89207826
2Mismatch repair_Homo sapiens_hsa034304.47393444
3Homologous recombination_Homo sapiens_hsa034403.57115173
4Nucleotide excision repair_Homo sapiens_hsa034203.29268393
5Fanconi anemia pathway_Homo sapiens_hsa034602.92213953
6Cell cycle_Homo sapiens_hsa041102.79391664
7Base excision repair_Homo sapiens_hsa034102.67497684
8Spliceosome_Homo sapiens_hsa030402.59121230
9RNA polymerase_Homo sapiens_hsa030202.33411869
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.32899306
11RNA degradation_Homo sapiens_hsa030182.21967149
12Basal transcription factors_Homo sapiens_hsa030222.18152664
13Non-homologous end-joining_Homo sapiens_hsa034502.16210758
14RNA transport_Homo sapiens_hsa030132.05512993
15Pyrimidine metabolism_Homo sapiens_hsa002402.01496653
16Systemic lupus erythematosus_Homo sapiens_hsa053221.89815863
17mRNA surveillance pathway_Homo sapiens_hsa030151.81647737
18Nitrogen metabolism_Homo sapiens_hsa009101.70385824
19One carbon pool by folate_Homo sapiens_hsa006701.57903808
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52450260
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.49552030
22Cysteine and methionine metabolism_Homo sapiens_hsa002701.43179558
23Ribosome_Homo sapiens_hsa030101.36309777
24Proteasome_Homo sapiens_hsa030501.35995704
25Purine metabolism_Homo sapiens_hsa002301.34179651
26Propanoate metabolism_Homo sapiens_hsa006401.34165672
27Alcoholism_Homo sapiens_hsa050341.30553819
28Oocyte meiosis_Homo sapiens_hsa041141.23539644
29Huntingtons disease_Homo sapiens_hsa050161.12456987
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.06483310
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.05853210
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.04782090
33Selenocompound metabolism_Homo sapiens_hsa004501.03498419
34p53 signaling pathway_Homo sapiens_hsa041151.01449926
35Basal cell carcinoma_Homo sapiens_hsa052170.93300217
36Viral carcinogenesis_Homo sapiens_hsa052030.93010810
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.92640378
38Pyruvate metabolism_Homo sapiens_hsa006200.90841973
39Herpes simplex infection_Homo sapiens_hsa051680.87683356
40Nicotine addiction_Homo sapiens_hsa050330.87197236
41Steroid biosynthesis_Homo sapiens_hsa001000.85554421
42Hedgehog signaling pathway_Homo sapiens_hsa043400.85491026
43Circadian entrainment_Homo sapiens_hsa047130.85487953
44Epstein-Barr virus infection_Homo sapiens_hsa051690.84545616
45Parkinsons disease_Homo sapiens_hsa050120.82309029
46Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79864772
47Folate biosynthesis_Homo sapiens_hsa007900.79832069
48Protein export_Homo sapiens_hsa030600.78312799
49MicroRNAs in cancer_Homo sapiens_hsa052060.77579476
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75914217
51HTLV-I infection_Homo sapiens_hsa051660.75742728
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.74410490
53Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73603929
54Bladder cancer_Homo sapiens_hsa052190.71511676
55Alzheimers disease_Homo sapiens_hsa050100.68765444
56N-Glycan biosynthesis_Homo sapiens_hsa005100.67982738
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67761467
58Transcriptional misregulation in cancer_Homo sapiens_hsa052020.66347932
59Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.66221855
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66028969
61Taste transduction_Homo sapiens_hsa047420.65586911
62Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65558164
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63013005
64Hippo signaling pathway_Homo sapiens_hsa043900.61716480
65Long-term potentiation_Homo sapiens_hsa047200.59510600
66Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58427229
67Hepatitis B_Homo sapiens_hsa051610.58268153
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.58176702
69Biosynthesis of amino acids_Homo sapiens_hsa012300.57664132
70Colorectal cancer_Homo sapiens_hsa052100.57636508
71Olfactory transduction_Homo sapiens_hsa047400.56474055
72Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.56156370
73Wnt signaling pathway_Homo sapiens_hsa043100.55584350
74Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.55125422
75Measles_Homo sapiens_hsa051620.54833591
76Inositol phosphate metabolism_Homo sapiens_hsa005620.52682016
77Regulation of autophagy_Homo sapiens_hsa041400.51805158
78Antigen processing and presentation_Homo sapiens_hsa046120.51256744
79Small cell lung cancer_Homo sapiens_hsa052220.49700376
80Oxidative phosphorylation_Homo sapiens_hsa001900.47405453
81Morphine addiction_Homo sapiens_hsa050320.46794148
82Butanoate metabolism_Homo sapiens_hsa006500.46495377
83Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.45734703
84Thyroid cancer_Homo sapiens_hsa052160.44869925
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43493059
86Long-term depression_Homo sapiens_hsa047300.43272252
87Metabolic pathways_Homo sapiens_hsa011000.42411140
88Oxytocin signaling pathway_Homo sapiens_hsa049210.38134482
89Glutamatergic synapse_Homo sapiens_hsa047240.37653307
90Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.37229927
91Primary immunodeficiency_Homo sapiens_hsa053400.36884579
92Serotonergic synapse_Homo sapiens_hsa047260.36785016
93cGMP-PKG signaling pathway_Homo sapiens_hsa040220.36085262
94Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36075930
95Amphetamine addiction_Homo sapiens_hsa050310.35867352
96MAPK signaling pathway_Homo sapiens_hsa040100.35620051
97Peroxisome_Homo sapiens_hsa041460.34676109
98Chronic myeloid leukemia_Homo sapiens_hsa052200.34597125
99Dopaminergic synapse_Homo sapiens_hsa047280.33813553
100Melanoma_Homo sapiens_hsa052180.32675423
101Cholinergic synapse_Homo sapiens_hsa047250.32506408
102Prostate cancer_Homo sapiens_hsa052150.31932314
103Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.31931246
104Circadian rhythm_Homo sapiens_hsa047100.31602328
105Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.31291794
106Cardiac muscle contraction_Homo sapiens_hsa042600.30922414
107Platelet activation_Homo sapiens_hsa046110.30881164
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.30663967
109Pathways in cancer_Homo sapiens_hsa052000.29601862
110TNF signaling pathway_Homo sapiens_hsa046680.29299374
111FoxO signaling pathway_Homo sapiens_hsa040680.29240033
112Lysine degradation_Homo sapiens_hsa003100.28981364
113Hematopoietic cell lineage_Homo sapiens_hsa046400.28833258
114Phototransduction_Homo sapiens_hsa047440.28648499
115African trypanosomiasis_Homo sapiens_hsa051430.27616108
116Pancreatic cancer_Homo sapiens_hsa052120.27576827
117Calcium signaling pathway_Homo sapiens_hsa040200.26559133
118Caffeine metabolism_Homo sapiens_hsa002320.26546378
119TGF-beta signaling pathway_Homo sapiens_hsa043500.26266571
120NOD-like receptor signaling pathway_Homo sapiens_hsa046210.25802177
121B cell receptor signaling pathway_Homo sapiens_hsa046620.25799544
122Renin secretion_Homo sapiens_hsa049240.25282756
123Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.23970228
124Gap junction_Homo sapiens_hsa045400.23900391
125T cell receptor signaling pathway_Homo sapiens_hsa046600.23803296
126Glutathione metabolism_Homo sapiens_hsa004800.23498424
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23379586
128Viral myocarditis_Homo sapiens_hsa054160.22849338
129Linoleic acid metabolism_Homo sapiens_hsa005910.22229313
130Arginine biosynthesis_Homo sapiens_hsa002200.22202444
131Shigellosis_Homo sapiens_hsa051310.22040047
132Fatty acid elongation_Homo sapiens_hsa000620.21232444
133Vitamin B6 metabolism_Homo sapiens_hsa007500.19808352
134Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.17639455
135Carbon metabolism_Homo sapiens_hsa012000.17071792
136Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.15143675
137Ether lipid metabolism_Homo sapiens_hsa005650.14253238
138alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.13589797
139Fatty acid metabolism_Homo sapiens_hsa012120.10981344
140Drug metabolism - other enzymes_Homo sapiens_hsa009830.10955122
141GABAergic synapse_Homo sapiens_hsa047270.09894821
142Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.09002721
143Retinol metabolism_Homo sapiens_hsa008300.06714310
144Tryptophan metabolism_Homo sapiens_hsa003800.06117759

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