SLFN5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation by symbiont of host defense response (GO:0052509)6.23680553
2modulation by symbiont of host defense response (GO:0052031)6.23680553
3modulation by organism of immune response of other organism involved in symbiotic interaction (GO:006.23680553
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:06.23680553
5positive regulation by organism of defense response of other organism involved in symbiotic interact6.23680553
6modulation by symbiont of host immune response (GO:0052553)6.23680553
7negative regulation of cell killing (GO:0031342)5.91809122
8negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.91809122
9positive regulation of interferon-alpha production (GO:0032727)5.53504012
10antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.32436099
11antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.32436099
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.27981718
13regulation of interferon-alpha production (GO:0032647)5.26212197
14negative T cell selection (GO:0043383)5.05177011
15antigen processing and presentation of endogenous antigen (GO:0019883)5.03286305
16response to type I interferon (GO:0034340)4.98220591
17type I interferon signaling pathway (GO:0060337)4.97845846
18cellular response to type I interferon (GO:0071357)4.97845846
19regulation of interferon-beta biosynthetic process (GO:0045357)4.88794856
20negative thymic T cell selection (GO:0045060)4.80078962
21positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.57054968
22response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.52965613
23response to host immune response (GO:0052572)4.52965613
24response to interferon-alpha (GO:0035455)4.40081293
25macrophage activation involved in immune response (GO:0002281)4.26807977
26response to interleukin-15 (GO:0070672)4.18432848
27cellular response to interleukin-15 (GO:0071350)4.17336640
28negative regulation of T cell mediated immunity (GO:0002710)4.16875005
29response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.06917905
30response to host (GO:0075136)4.06917905
31response to host defenses (GO:0052200)4.06917905
32response to peptidoglycan (GO:0032494)4.03703745
33positive regulation of gamma-delta T cell activation (GO:0046645)4.03098176
34positive T cell selection (GO:0043368)4.02512510
35immunoglobulin mediated immune response (GO:0016064)4.01767171
36positive regulation of antigen processing and presentation (GO:0002579)3.96444954
37positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.96351068
38positive regulation of interferon-beta production (GO:0032728)3.89916820
39interferon-gamma-mediated signaling pathway (GO:0060333)3.79439646
40positive thymic T cell selection (GO:0045059)3.77035240
41cellular response to interferon-alpha (GO:0035457)3.74274522
42regulation of dendritic cell antigen processing and presentation (GO:0002604)3.73186847
43T cell selection (GO:0045058)3.69590284
44thymic T cell selection (GO:0045061)3.66155592
45microglial cell activation (GO:0001774)3.64741926
46leukocyte aggregation (GO:0070486)3.62759286
47positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.61925336
48neutrophil activation involved in immune response (GO:0002283)3.59046999
49positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.55672540
50regulation of T cell tolerance induction (GO:0002664)3.50266062
51positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.48427286
52interferon-gamma production (GO:0032609)3.47231912
53positive regulation of tolerance induction (GO:0002645)3.44802378
54negative regulation of lymphocyte mediated immunity (GO:0002707)3.44739394
55cellular response to virus (GO:0098586)3.42698383
56antigen processing and presentation via MHC class Ib (GO:0002475)3.40235020
57regulation of antigen processing and presentation (GO:0002577)3.37525756
58activated T cell proliferation (GO:0050798)3.36325191
59negative regulation of viral genome replication (GO:0045071)3.35966486
60low-density lipoprotein particle clearance (GO:0034383)3.35124916
61lipopolysaccharide-mediated signaling pathway (GO:0031663)3.33892650
62positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.33144851
63I-kappaB phosphorylation (GO:0007252)3.33081154
64regulation of cholesterol storage (GO:0010885)3.33028235
65tolerance induction (GO:0002507)3.29439697
66regulation of tolerance induction (GO:0002643)3.28853286
67response to muramyl dipeptide (GO:0032495)3.27657419
68positive regulation of natural killer cell differentiation (GO:0032825)3.26814350
69regulation of T cell mediated cytotoxicity (GO:0001914)3.26404298
70regulation of alpha-beta T cell proliferation (GO:0046640)3.24301716
71regulation of regulatory T cell differentiation (GO:0045589)3.23694843
72positive regulation of granulocyte differentiation (GO:0030854)3.17355713
73regulation of type I interferon-mediated signaling pathway (GO:0060338)3.17309450
74cellular response to interferon-beta (GO:0035458)3.17206979
75regulation of T-helper 1 cell differentiation (GO:0045625)3.16011700
76T cell migration (GO:0072678)3.15964266
77positive regulation of toll-like receptor signaling pathway (GO:0034123)3.14926233
78negative regulation of leukocyte mediated immunity (GO:0002704)3.14028416
79JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.09778364
80regulation of interleukin-12 biosynthetic process (GO:0045075)3.07679078
81macrophage activation (GO:0042116)3.07631236
82regulation of necroptotic process (GO:0060544)3.05333200
83positive regulation of interleukin-12 production (GO:0032735)3.05227459
84regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.03887441
85T-helper 1 type immune response (GO:0042088)3.03212747
86regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.02257246
87regulation of natural killer cell mediated immunity (GO:0002715)3.01828902
88regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.01828902
89response to interferon-beta (GO:0035456)2.99892980
90positive regulation of alpha-beta T cell proliferation (GO:0046641)2.99656847
91positive regulation of T cell mediated cytotoxicity (GO:0001916)2.97844720
92regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.97023571
93detection of molecule of bacterial origin (GO:0032490)2.95847022
94regulation of B cell receptor signaling pathway (GO:0050855)2.94348627
95regulation of isotype switching to IgG isotypes (GO:0048302)2.94296234
96lymphocyte migration (GO:0072676)2.90712530
97B cell receptor signaling pathway (GO:0050853)2.89765590
98regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.87600227
99regulation of leukocyte mediated cytotoxicity (GO:0001910)2.87458321
100respiratory burst (GO:0045730)2.86833364
101negative regulation of type 2 immune response (GO:0002829)2.86090864
102positive regulation of macrophage cytokine production (GO:0060907)2.85589760
103regulation of interferon-beta production (GO:0032648)2.84962671
104myeloid cell activation involved in immune response (GO:0002275)2.84367144
105vascular endothelial growth factor signaling pathway (GO:0038084)2.84045643
106regulation of gamma-delta T cell activation (GO:0046643)2.83756516
107detection of other organism (GO:0098543)2.83415551
108positive regulation of chemokine biosynthetic process (GO:0045080)2.82335106
109regulation of RIG-I signaling pathway (GO:0039535)2.82023256
110B cell mediated immunity (GO:0019724)2.81480438
111cellular response to interferon-gamma (GO:0071346)2.81405560
112germinal center formation (GO:0002467)2.80584668
113T cell receptor signaling pathway (GO:0050852)2.79789894
114regulation of B cell differentiation (GO:0045577)2.79754686
115granulocyte activation (GO:0036230)2.78765873
116negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.76518168
117regulation of interleukin-8 biosynthetic process (GO:0045414)2.76289204
118cellular response to exogenous dsRNA (GO:0071360)2.76287329
119defense response to virus (GO:0051607)2.75719513
120neutrophil activation (GO:0042119)2.75215361
121positive regulation of cellular amide metabolic process (GO:0034250)2.72891521
122NIK/NF-kappaB signaling (GO:0038061)2.71453148
123positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.70169124
124myeloid dendritic cell differentiation (GO:0043011)2.70110202
125regulation of cell killing (GO:0031341)2.69435597
126cellular extravasation (GO:0045123)2.69044130
127detection of bacterium (GO:0016045)2.68258760
128regulation of interleukin-12 production (GO:0032655)2.67420590
129antigen receptor-mediated signaling pathway (GO:0050851)2.67075926
130negative regulation of interleukin-12 production (GO:0032695)2.66656501
131regulation of interferon-gamma biosynthetic process (GO:0045072)2.66286943
132substrate-dependent cell migration (GO:0006929)2.65281904
133regulation of interleukin-2 biosynthetic process (GO:0045076)2.65173402
134positive regulation of natural killer cell mediated immunity (GO:0002717)2.63296342
135retina vasculature morphogenesis in camera-type eye (GO:0061299)2.63148211
136regulation of mononuclear cell migration (GO:0071675)2.62540099
137dendritic cell migration (GO:0036336)2.59961033
138negative regulation of adaptive immune response (GO:0002820)2.59866685
139phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.59646515
140positive regulation of lipid storage (GO:0010884)2.57896721
141positive regulation of type 2 immune response (GO:0002830)2.57848572
142positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.57744216
143natural killer cell mediated immunity (GO:0002228)2.56151753
144natural killer cell mediated cytotoxicity (GO:0042267)2.56151753
145positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.55618901
146regulation of MHC class I biosynthetic process (GO:0045343)2.55274798
147regulation of gamma-delta T cell differentiation (GO:0045586)2.55015678
148hypotonic response (GO:0006971)2.54090556
149positive regulation of humoral immune response (GO:0002922)2.53677780
150defense response to protozoan (GO:0042832)2.53223370
151myeloid dendritic cell activation (GO:0001773)2.53170093
152lymph node development (GO:0048535)2.53022282
153positive regulation of isotype switching (GO:0045830)2.52943990
154hepatocyte apoptotic process (GO:0097284)2.52851021
155pinocytosis (GO:0006907)2.52826039
156positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.52824159
157lymphocyte chemotaxis (GO:0048247)2.52799379
158regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.52281092
159negative regulation of B cell proliferation (GO:0030889)2.51689080
160regulation of response to interferon-gamma (GO:0060330)2.51530101
161negative regulation of T-helper cell differentiation (GO:0045623)2.51248201
162negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.51248201
163positive regulation of interleukin-2 production (GO:0032743)2.51228111
164positive regulation of macrophage differentiation (GO:0045651)2.50804250

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.86208995
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.94515767
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human5.60356258
4BP1_19119308_ChIP-ChIP_Hs578T_Human5.04555059
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.51322274
6* IRF8_27001747_Chip-Seq_BMDM_Mouse3.89213934
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.84989574
8* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.42847558
9* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.27516490
10* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.03289355
11Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.88442534
12* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.64870473
13RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.63100250
14GATA1_22025678_ChIP-Seq_K562_Human2.43430718
15* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.42254152
16STAT4_19710469_ChIP-ChIP_TH1__Mouse2.32862995
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.31549227
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.22777592
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.21873628
20* GATA2_21666600_ChIP-Seq_HMVEC_Human2.02231495
21SMAD_19615063_ChIP-ChIP_OVARY_Human1.99607775
22STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.96552400
23RUNX_20019798_ChIP-Seq_JUKART_Human1.94007406
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.91796872
25SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.78606197
26PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.77432875
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.73864872
28THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.73813374
29NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.71663882
30PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.66354422
31TRIM28_21343339_ChIP-Seq_HEK293_Human1.62464168
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.57153926
33* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.57080333
34VDR_24787735_ChIP-Seq_THP-1_Human1.56022068
35SPI1_23127762_ChIP-Seq_K562_Human1.55318081
36SCL_19346495_ChIP-Seq_HPC-7_Human1.54259355
37PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.53702748
38TP63_17297297_ChIP-ChIP_HaCaT_Human1.50006602
39* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.49152557
40* MAF_26560356_Chip-Seq_TH1_Human1.42924921
41PU_27001747_Chip-Seq_BMDM_Mouse1.42275552
42* MYB_26560356_Chip-Seq_TH2_Human1.37324862
43* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.36012855
44SPI1_23547873_ChIP-Seq_NB4_Human1.33372828
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.32663520
46RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.23071419
47CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.19410244
48* MYB_26560356_Chip-Seq_TH1_Human1.17581364
49NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.14963273
50CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14361843
51VDR_24763502_ChIP-Seq_THP-1_Human1.13131948
52STAT6_21828071_ChIP-Seq_BEAS2B_Human1.13018664
53* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12847611
54RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.10360941
55KDM2B_26808549_Chip-Seq_SUP-B15_Human1.09423775
56RUNX1_22412390_ChIP-Seq_EML_Mouse1.08709971
57KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07402915
58CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.05159717
59* CJUN_26792858_Chip-Seq_BT549_Human1.04081734
60* ELK3_25401928_ChIP-Seq_HUVEC_Human1.01370621
61GATA3_27048872_Chip-Seq_THYMUS_Human1.01202865
62ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93503743
63E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.92697280
64* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.92640072
65SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.92371320
66* GATA3_26560356_Chip-Seq_TH2_Human0.92162583
67MYC_22102868_ChIP-Seq_BL_Human0.91616869
68PPAR_26484153_Chip-Seq_NCI-H1993_Human0.90635114
69* SOX2_20726797_ChIP-Seq_SW620_Human0.90297003
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.90008703
71LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.89378564
72RARG_19884340_ChIP-ChIP_MEFs_Mouse0.89349989
73EGR1_19032775_ChIP-ChIP_M12_Human0.89134846
74BRD4_25478319_ChIP-Seq_HGPS_Human0.88933044
75TP53_16413492_ChIP-PET_HCT116_Human0.87683821
76GATA1_19941826_ChIP-Seq_K562_Human0.87527204
77CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86257590
78SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85691045
79KDM2B_26808549_Chip-Seq_JURKAT_Human0.85671604
80BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.85668178
81UTX_26944678_Chip-Seq_JUKART_Human0.84954171
82LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.84530639
83MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.84091911
84ESR1_20079471_ChIP-ChIP_T-47D_Human0.83856458
85* FOXO3_23340844_ChIP-Seq_DLD1_Human0.83604478
86TP63_23658742_ChIP-Seq_EP156T_Human0.83280805
87GATA2_19941826_ChIP-Seq_K562_Human0.82515710
88NOTCH1_21737748_ChIP-Seq_TLL_Human0.82279229
89CLOCK_20551151_ChIP-Seq_293T_Human0.81786230
90NRF2_20460467_ChIP-Seq_MEFs_Mouse0.81505199
91NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.81505199
92PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81196452
93GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.81164391
94ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.80149715
95* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79559801
96GATA1_19941827_ChIP-Seq_MEL_Mouse0.79189213
97ZNF217_24962896_ChIP-Seq_MCF-7_Human0.79170051
98TBX20_22328084_ChIP-Seq_HEART_Mouse0.79053139
99TBX20_22080862_ChIP-Seq_HEART_Mouse0.79053139
100SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.78635896
101SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.78635896
102TCF7_22412390_ChIP-Seq_EML_Mouse0.78069468
103GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77725660
104GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77510284
105LXR_22158963_ChIP-Seq_LIVER_Mouse0.77240267
106* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.76372849
107* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75486684
108* P63_26484246_Chip-Seq_KERATINOCYTES_Human0.75199739
109GATA2_22383799_ChIP-Seq_G1ME_Mouse0.74931275
110VDR_21846776_ChIP-Seq_THP-1_Human0.74729254
111ESR1_21235772_ChIP-Seq_MCF-7_Human0.74678951
112CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.74435809
113* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.73857370
114KDM2B_26808549_Chip-Seq_DND41_Human0.73547570
115RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.73277151
116ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.70636313
117CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.70442764
118PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.69150867
119MAF_26560356_Chip-Seq_TH2_Human0.69005852
120TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.68794731
121ESR2_21235772_ChIP-Seq_MCF-7_Human0.67274069

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.00376607
2MP0003724_increased_susceptibility_to3.88145472
3MP0003303_peritoneal_inflammation3.36131739
4MP0009785_altered_susceptibility_to3.22935862
5MP0003436_decreased_susceptibility_to3.02005183
6MP0004510_myositis2.94139561
7MP0001790_abnormal_immune_system2.85785276
8MP0005387_immune_system_phenotype2.85785276
9MP0002148_abnormal_hypersensitivity_rea2.72437277
10MP0005000_abnormal_immune_tolerance2.70306602
11MP0002419_abnormal_innate_immunity2.63255502
12MP0005025_abnormal_response_to2.60760880
13MP0000685_abnormal_immune_system2.44930872
14MP0006082_CNS_inflammation2.39795472
15MP0001800_abnormal_humoral_immune2.34518439
16MP0002452_abnormal_antigen_presenting2.32328148
17MP0005058_abnormal_lysosome_morphology2.23825377
18MP0002723_abnormal_immune_serum2.21740120
19MP0005671_abnormal_response_to2.16323384
20MP0001533_abnormal_skeleton_physiology2.06949273
21MP0000343_altered_response_to2.06821570
22MP0003828_pulmonary_edema1.99007423
23MP0003300_gastrointestinal_ulcer1.95086558
24MP0001819_abnormal_immune_cell1.93125873
25MP0002420_abnormal_adaptive_immunity1.89736063
26MP0002166_altered_tumor_susceptibility1.88959724
27MP0001879_abnormal_lymphatic_vessel1.82250055
28MP0005167_abnormal_blood-brain_barrier1.81564811
29MP0008438_abnormal_cutaneous_collagen1.76136363
30MP0009278_abnormal_bone_marrow1.75495161
31MP0004947_skin_inflammation1.72555046
32MP0003448_altered_tumor_morphology1.70708352
33MP0002006_tumorigenesis1.66630436
34MP0004883_abnormal_blood_vessel1.65488219
35MP0001853_heart_inflammation1.64461954
36MP0009764_decreased_sensitivity_to1.63180442
37MP0001845_abnormal_inflammatory_respons1.60662557
38MP0008469_abnormal_protein_level1.58864261
39MP0005464_abnormal_platelet_physiology1.58813252
40MP0003191_abnormal_cellular_cholesterol1.55469518
41MP0002405_respiratory_system_inflammati1.55377771
42MP0010155_abnormal_intestine_physiology1.52944086
43MP0003866_abnormal_defecation1.51886178
44MP0000703_abnormal_thymus_morphology1.51324248
45MP0010368_abnormal_lymphatic_system1.47139516
46MP0004381_abnormal_hair_follicle1.45504853
47MP0004130_abnormal_muscle_cell1.41548153
48MP0006054_spinal_hemorrhage1.40319873
49MP0000716_abnormal_immune_system1.39557607
50MP0002998_abnormal_bone_remodeling1.36850243
51MP0008260_abnormal_autophagy1.34766676
52MP0001958_emphysema1.32904655
53MP0003566_abnormal_cell_adhesion1.31814521
54MP0001851_eye_inflammation1.30944461
55MP0003172_abnormal_lysosome_physiology1.28602253
56MP0003690_abnormal_glial_cell1.28250461
57MP0003075_altered_response_to1.28129649
58MP0002398_abnormal_bone_marrow1.27605081
59MP0005310_abnormal_salivary_gland1.26497946
60MP0005397_hematopoietic_system_phenotyp1.21985552
61MP0001545_abnormal_hematopoietic_system1.21985552
62MP0000767_abnormal_smooth_muscle1.19544150
63MP0005670_abnormal_white_adipose1.19354548
64MP0002138_abnormal_hepatobiliary_system1.16797487
65MP0003091_abnormal_cell_migration1.15550312
66MP0000604_amyloidosis1.13421168
67MP0003045_fibrosis1.12286131
68MP0005164_abnormal_response_to1.11896507
69MP0009840_abnormal_foam_cell1.11334078
70MP0002429_abnormal_blood_cell1.10460068
71MP0000249_abnormal_blood_vessel1.09420593
72MP0005451_abnormal_body_composition1.08880687
73MP0002933_joint_inflammation1.08099125
74MP0000689_abnormal_spleen_morphology1.06452659
75MP0009763_increased_sensitivity_to1.00968445
76MP0005390_skeleton_phenotype0.99992754
77MP0002877_abnormal_melanocyte_morpholog0.96910144
78MP0008775_abnormal_heart_ventricle0.96358790
79MP0000569_abnormal_digit_pigmentation0.96249453
80MP0004782_abnormal_surfactant_physiolog0.95617770
81MP0002396_abnormal_hematopoietic_system0.94938001
82MP0001348_abnormal_lacrimal_gland0.94048484
83MP0003763_abnormal_thymus_physiology0.93766993
84MP0002722_abnormal_immune_system0.93548950
85MP0004272_abnormal_basement_membrane0.93048140
86MP0002009_preneoplasia0.92764193
87MP0002254_reproductive_system_inflammat0.91887666
88MP0009333_abnormal_splenocyte_physiolog0.91814657
89MP0002168_other_aberrant_phenotype0.91795831
90MP0005503_abnormal_tendon_morphology0.90944674
91MP0004084_abnormal_cardiac_muscle0.89329328
92MP0000858_altered_metastatic_potential0.89306225
93MP0005165_increased_susceptibility_to0.88489669
94MP0001542_abnormal_bone_strength0.88130398
95MP0002277_abnormal_respiratory_mucosa0.87538356
96MP0004185_abnormal_adipocyte_glucose0.86566353
97MP0003453_abnormal_keratinocyte_physiol0.85640836
98MP0001873_stomach_inflammation0.85107489
99MP0005166_decreased_susceptibility_to0.83663668
100MP0005666_abnormal_adipose_tissue0.82449745
101MP0004808_abnormal_hematopoietic_stem0.82117835
102MP0002332_abnormal_exercise_endurance0.81781491
103MP0003795_abnormal_bone_structure0.80257994
104MP0010352_gastrointestinal_tract_polyps0.80204146
105MP0003656_abnormal_erythrocyte_physiolo0.78089467
106MP0001544_abnormal_cardiovascular_syste0.77517172
107MP0005385_cardiovascular_system_phenoty0.77517172
108MP0009115_abnormal_fat_cell0.76941294
109MP0003705_abnormal_hypodermis_morpholog0.75505736
110MP0002136_abnormal_kidney_physiology0.74425317
111MP0005275_abnormal_skin_tensile0.73884775
112MP0003183_abnormal_peptide_metabolism0.73650465
113MP0008004_abnormal_stomach_pH0.73403983
114MP0003279_aneurysm0.71112481
115MP0000465_gastrointestinal_hemorrhage0.70384581
116MP0000015_abnormal_ear_pigmentation0.69793379
117MP0010307_abnormal_tumor_latency0.69198810
118MP0000750_abnormal_muscle_regeneration0.67028978
119MP0003950_abnormal_plasma_membrane0.64882272
120MP0002133_abnormal_respiratory_system0.64635808
121MP0005388_respiratory_system_phenotype0.64635808
122MP0005075_abnormal_melanosome_morpholog0.64443819
123MP0003646_muscle_fatigue0.63734441
124MP0002060_abnormal_skin_morphology0.63058043
125MP0005023_abnormal_wound_healing0.62486367

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)5.80607504
2Recurrent abscess formation (HP:0002722)5.53742122
3Eczematoid dermatitis (HP:0000976)5.50076975
4Abnormality of T cell number (HP:0011839)5.46844049
5Recurrent bacterial skin infections (HP:0005406)4.88230004
6Systemic lupus erythematosus (HP:0002725)4.31291644
7Myositis (HP:0100614)4.30352116
8Recurrent gram-negative bacterial infections (HP:0005420)4.29704832
9Elevated erythrocyte sedimentation rate (HP:0003565)4.28818224
10Chronic otitis media (HP:0000389)4.26092664
11Orchitis (HP:0100796)4.19748997
12Autoimmune thrombocytopenia (HP:0001973)4.19659756
13Abnormality of macrophages (HP:0004311)4.19050130
14Hematochezia (HP:0002573)4.10169739
15Increased cerebral lipofuscin (HP:0011813)3.76885090
16Abnormality of the nasal mucosa (HP:0000433)3.69500488
17Retrobulbar optic neuritis (HP:0100654)3.66813792
18Optic neuritis (HP:0100653)3.66813792
19Spontaneous hematomas (HP:0007420)3.61721729
20Abnormality of T cells (HP:0002843)3.56674415
21Mediastinal lymphadenopathy (HP:0100721)3.55394654
22Vacuolated lymphocytes (HP:0001922)3.55051736
23Basal ganglia calcification (HP:0002135)3.33676079
24Gastrointestinal infarctions (HP:0005244)3.30855186
25Vasculitis (HP:0002633)3.30555267
26Recurrent fungal infections (HP:0002841)3.29280481
27Gingivitis (HP:0000230)3.28382562
28Recurrent viral infections (HP:0004429)3.26218802
29Recurrent skin infections (HP:0001581)3.25409636
30Prostate neoplasm (HP:0100787)3.25017309
31Increased neuronal autofluorescent lipopigment (HP:0002074)3.21675827
32Tetraparesis (HP:0002273)3.19794854
33Myocardial infarction (HP:0001658)3.18659669
34Porencephaly (HP:0002132)3.13079590
35Nasal polyposis (HP:0100582)3.07608450
36Glomerulonephritis (HP:0000099)2.89595932
37Pulmonary infiltrates (HP:0002113)2.84581943
38Stomatitis (HP:0010280)2.83900940
39Increased IgM level (HP:0003496)2.81751086
40Interstitial pulmonary disease (HP:0006530)2.80869508
41Spondylolisthesis (HP:0003302)2.79053530
42Thick nail (HP:0001805)2.77295283
43Axonal loss (HP:0003447)2.75196955
44Nephritis (HP:0000123)2.74832413
45Aortic aneurysm (HP:0004942)2.70665772
46Esophageal varix (HP:0002040)2.70060617
47Obstructive lung disease (HP:0006536)2.67338043
48Chronic obstructive pulmonary disease (HP:0006510)2.67338043
49Abnormality of eosinophils (HP:0001879)2.64430877
50Colitis (HP:0002583)2.64398778
51Loss of speech (HP:0002371)2.64152538
52IgG deficiency (HP:0004315)2.61116006
53Encephalitis (HP:0002383)2.60745467
54Recurrent cutaneous fungal infections (HP:0011370)2.60669261
55Chronic mucocutaneous candidiasis (HP:0002728)2.60669261
56Cellulitis (HP:0100658)2.58368757
57Recurrent bronchitis (HP:0002837)2.57885780
58Chronic diarrhea (HP:0002028)2.53761803
59Keratoconjunctivitis sicca (HP:0001097)2.53263150
60Hemoptysis (HP:0002105)2.49454911
61Hypergammaglobulinemia (HP:0010702)2.48867208
62Arterial thrombosis (HP:0004420)2.48652004
63Pustule (HP:0200039)2.46134468
64Granulocytopenia (HP:0001913)2.43757048
65Aortic dissection (HP:0002647)2.42275796
66Severe combined immunodeficiency (HP:0004430)2.40409475
67Polycythemia (HP:0001901)2.40137911
68Inflammation of the large intestine (HP:0002037)2.38288898
69Chronic sinusitis (HP:0011109)2.37351548
70Increased IgE level (HP:0003212)2.35635289
71Osteolytic defects of the hand bones (HP:0009699)2.31883031
72Osteolytic defects of the phalanges of the hand (HP:0009771)2.31883031
73Periodontitis (HP:0000704)2.31609810
74Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.31495155
75Dysostosis multiplex (HP:0000943)2.30675363
76Chest pain (HP:0100749)2.29940009
77Abnormality of T cell physiology (HP:0011840)2.29838524
78Vascular tortuosity (HP:0004948)2.29503329
79Pulmonary artery stenosis (HP:0004415)2.28129514
80Subacute progressive viral hepatitis (HP:0006572)2.27876528
81Disinhibition (HP:0000734)2.27019118
82Leukocytosis (HP:0001974)2.26746407
83Emphysema (HP:0002097)2.25783662
84Keratoconjunctivitis (HP:0001096)2.25709569
85Joint hemorrhage (HP:0005261)2.23240538
86Arterial tortuosity (HP:0005116)2.21488836
87Glucose intolerance (HP:0000833)2.20912498
88Autoimmune hemolytic anemia (HP:0001890)2.20817001
89Gingival bleeding (HP:0000225)2.20336888
90Dilatation of the ascending aorta (HP:0005111)2.14728269
91Meningitis (HP:0001287)2.14643653
92Abnormality of liposaccharide metabolism (HP:0010968)2.13955376
93Abnormality of glycosphingolipid metabolism (HP:0004343)2.13955376
94Abnormality of glycolipid metabolism (HP:0010969)2.13955376
95Panhypogammaglobulinemia (HP:0003139)2.13118546
96Gastrointestinal inflammation (HP:0004386)2.12033755
97Urticaria (HP:0001025)2.11961022
98Lymphopenia (HP:0001888)2.10724765
99Osteomyelitis (HP:0002754)2.10507848
100Abnormality of cells of the lymphoid lineage (HP:0012140)2.09097399
101Protrusio acetabuli (HP:0003179)2.08782552
102IgA deficiency (HP:0002720)2.08763846
103Epistaxis (HP:0000421)2.07816148
104Mucopolysacchariduria (HP:0008155)2.07616425
105Urinary glycosaminoglycan excretion (HP:0003541)2.07616425
106Joint swelling (HP:0001386)2.07042353
107Milia (HP:0001056)2.06758530
108Hepatosplenomegaly (HP:0001433)2.06194494
109Thyroiditis (HP:0100646)2.05640409
110Prolonged bleeding time (HP:0003010)2.03976349
111Complement deficiency (HP:0004431)2.03841488
112Eosinophilia (HP:0001880)2.03497431
113Abnormality of the vasculature of the conjunctiva (HP:0008054)2.03289079
114Abnormal delayed hypersensitivity skin test (HP:0002963)2.02053513
115Bronchitis (HP:0012387)2.00656786
116Pulmonary embolism (HP:0002204)1.99762349
117Amyloidosis (HP:0011034)1.99611687
118Abnormality of mucopolysaccharide metabolism (HP:0011020)1.99368394
119Abnormality of polysaccharide metabolism (HP:0011012)1.99368394
120Abnormality of glycosaminoglycan metabolism (HP:0004371)1.99368394
121Absent frontal sinuses (HP:0002688)1.99180953
122Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.99115083
123Hemorrhage of the eye (HP:0011885)1.98790753
124Papilledema (HP:0001085)1.97713942
125Recurrent lower respiratory tract infections (HP:0002783)1.94781784
126Conjunctival telangiectasia (HP:0000524)1.94558417
127Syringomyelia (HP:0003396)1.93979848
128Spinal cord lesions (HP:0100561)1.93979848
129Recurrent pneumonia (HP:0006532)1.93693238
130Peritonitis (HP:0002586)1.89418414
131Frequent falls (HP:0002359)1.87679996
132Increased connective tissue (HP:0009025)1.87106561
133Asymmetric septal hypertrophy (HP:0001670)1.86744487
134Papilloma (HP:0012740)1.86445654
135Verrucae (HP:0200043)1.86445654
136Nausea (HP:0002018)1.86365362
137Skin ulcer (HP:0200042)1.85179435
138Atrophic scars (HP:0001075)1.84350689
139Abnormality of the fingertips (HP:0001211)1.83706120
140Anorexia (HP:0002039)1.83070351
141Viral hepatitis (HP:0006562)1.81285080
142Slow saccadic eye movements (HP:0000514)1.78914371
143Glomerulopathy (HP:0100820)1.78704610
144Gangrene (HP:0100758)1.78256407

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TYK23.94617751
2MAP3K143.44439226
3TIE13.35279986
4TBK13.25397027
5IKBKE3.11104080
6JAK12.92434643
7JAK32.79819872
8BLK2.78950846
9KIT2.72228111
10IRAK32.62518003
11IRAK42.58579032
12FGFR42.53645228
13TGFBR22.35648379
14PRPF4B2.30252510
15EPHB12.29028184
16ERN12.23668468
17MAP4K12.23455613
18KDR2.21943857
19FGFR32.01658304
20IKBKB1.97046826
21RIPK41.82718186
22EPHA31.81306191
23MAP3K131.80596428
24CSK1.79433914
25TTN1.68045670
26TXK1.65986083
27GRK61.65324737
28RIPK11.60598755
29CAMK1D1.44842108
30CAMKK21.35916423
31PIK3CG1.34181519
32HCK1.27689309
33FES1.23997403
34ZAP701.23088164
35JAK21.21265419
36CHUK1.17662514
37IRAK11.16065087
38LCK1.06708365
39CDC42BPA1.05882548
40DMPK1.05140519
41CAMK1G1.04777542
42CSF1R1.02339194
43SYK1.01625431
44FGR0.97330343
45PBK0.96178526
46STK380.95948638
47NEK90.95086555
48MAPK70.92740738
49PDGFRA0.91173977
50MARK30.91063333
51BMPR20.89282729
52MELK0.88849782
53TEC0.88827518
54TAOK30.83926647
55BTK0.83618392
56CDK120.81639242
57HIPK20.80734089
58PTK60.80251453
59NLK0.79981404
60STK100.79788285
61TRIB30.78806396
62MARK20.78475712
63MAP3K70.78122909
64LYN0.77982988
65MAP2K30.76757618
66TRPM70.76468370
67MAPK110.75480906
68PIM20.75187298
69MOS0.74083791
70EIF2AK20.73608252
71GRK70.73011810
72ITK0.72541550
73DDR20.71692591
74PKN10.69503016
75PRKD20.68560806
76AKT30.66186853
77TGFBR10.65496662
78MST1R0.64090222
79SIK20.63570609
80CDK60.62848082
81MAP3K100.62583661
82BMX0.62333072
83MAP3K20.62287948
84SIK10.61639455
85MAP3K30.61363436
86EGFR0.59937952
87PRKAA20.59403885
88MAP3K50.59267603
89WNK10.56871752
90MATK0.55870155
91RPS6KA40.55710669
92ABL10.55644606
93SGK20.54560652
94CAMKK10.51305141
95TNK20.50649242
96PIM10.50475204
97PRKCQ0.49764965
98NUAK10.49339629
99LRRK20.49222230
100PRKCH0.48869298
101YES10.48565989
102GRK50.47635884
103PTK2B0.47456811
104IRAK20.47235146
105GSK3A0.46526494
106PDGFRB0.45647829
107MYLK0.44069884
108STK40.43117689
109PDPK10.40682286
110PRKG20.39499943
111STK30.38846680
112IGF1R0.38695159
113PRKCD0.37998986
114RET0.37255308
115NEK60.37176919
116PIK3CA0.36958944
117ABL20.36875807
118SIK30.36872133
119CDK40.35768601
120TYRO30.33999293
121PRKD10.32751951
122FYN0.32662701
123PDK10.31529442
124INSR0.30432037
125STK240.30203371
126SGK30.29365371
127OBSCN0.28496664
128MAP3K10.27380881
129MAPK120.26707287
130GRK10.25145375
131PKN20.25136152
132SRC0.24679271

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.94478786
2Staphylococcus aureus infection_Homo sapiens_hsa051502.91333308
3Toll-like receptor signaling pathway_Homo sapiens_hsa046202.88757170
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.59070980
5Measles_Homo sapiens_hsa051622.47298859
6RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.46837857
7Malaria_Homo sapiens_hsa051442.42611654
8Osteoclast differentiation_Homo sapiens_hsa043802.41596403
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.14768698
10Allograft rejection_Homo sapiens_hsa053302.13083510
11Influenza A_Homo sapiens_hsa051642.06908167
12Graft-versus-host disease_Homo sapiens_hsa053322.01650208
13Pertussis_Homo sapiens_hsa051331.99196812
14Intestinal immune network for IgA production_Homo sapiens_hsa046721.93496830
15Toxoplasmosis_Homo sapiens_hsa051451.88277808
16TNF signaling pathway_Homo sapiens_hsa046681.87808169
17Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.85032177
18Tuberculosis_Homo sapiens_hsa051521.78136760
19NOD-like receptor signaling pathway_Homo sapiens_hsa046211.70174055
20B cell receptor signaling pathway_Homo sapiens_hsa046621.66624336
21Herpes simplex infection_Homo sapiens_hsa051681.65276359
22African trypanosomiasis_Homo sapiens_hsa051431.59872725
23Legionellosis_Homo sapiens_hsa051341.56967515
24Viral myocarditis_Homo sapiens_hsa054161.53815762
25Rheumatoid arthritis_Homo sapiens_hsa053231.53412369
26Lysosome_Homo sapiens_hsa041421.50537292
27Hepatitis C_Homo sapiens_hsa051601.50402690
28Jak-STAT signaling pathway_Homo sapiens_hsa046301.49024649
29Glycosaminoglycan degradation_Homo sapiens_hsa005311.48845884
30Antigen processing and presentation_Homo sapiens_hsa046121.44037955
31Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.42589318
32Chemokine signaling pathway_Homo sapiens_hsa040621.37673399
33Asthma_Homo sapiens_hsa053101.35974261
34Primary immunodeficiency_Homo sapiens_hsa053401.33580051
35AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.32766881
36Apoptosis_Homo sapiens_hsa042101.30568771
37Hematopoietic cell lineage_Homo sapiens_hsa046401.29502226
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.28000549
39Caffeine metabolism_Homo sapiens_hsa002321.25306854
40Autoimmune thyroid disease_Homo sapiens_hsa053201.24989210
41Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.23346829
42Salmonella infection_Homo sapiens_hsa051321.22181124
43Leukocyte transendothelial migration_Homo sapiens_hsa046701.20790484
44Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.19605190
45Non-small cell lung cancer_Homo sapiens_hsa052231.19382619
46Phagosome_Homo sapiens_hsa041451.19220099
47Hepatitis B_Homo sapiens_hsa051611.13800902
48Adipocytokine signaling pathway_Homo sapiens_hsa049201.11759305
49Other glycan degradation_Homo sapiens_hsa005111.05938426
50Amoebiasis_Homo sapiens_hsa051461.05936373
51Shigellosis_Homo sapiens_hsa051310.99989383
52T cell receptor signaling pathway_Homo sapiens_hsa046600.93517521
53Acute myeloid leukemia_Homo sapiens_hsa052210.91901716
54Small cell lung cancer_Homo sapiens_hsa052220.90549550
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89912880
56Complement and coagulation cascades_Homo sapiens_hsa046100.87248228
57FoxO signaling pathway_Homo sapiens_hsa040680.85577909
58Prolactin signaling pathway_Homo sapiens_hsa049170.84593942
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.84148978
60Platelet activation_Homo sapiens_hsa046110.83704980
61Notch signaling pathway_Homo sapiens_hsa043300.80088485
62Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.75956257
63Insulin resistance_Homo sapiens_hsa049310.75509534
64Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.74149029
65Type I diabetes mellitus_Homo sapiens_hsa049400.73525294
66Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.72809147
67Focal adhesion_Homo sapiens_hsa045100.71768128
68Pancreatic cancer_Homo sapiens_hsa052120.71668911
69Inositol phosphate metabolism_Homo sapiens_hsa005620.71590194
70Endometrial cancer_Homo sapiens_hsa052130.69815434
71Prostate cancer_Homo sapiens_hsa052150.69734935
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69557250
73ECM-receptor interaction_Homo sapiens_hsa045120.68631575
74HIF-1 signaling pathway_Homo sapiens_hsa040660.66544363
75Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.65213001
76mTOR signaling pathway_Homo sapiens_hsa041500.64906082
77Type II diabetes mellitus_Homo sapiens_hsa049300.64903903
78Chronic myeloid leukemia_Homo sapiens_hsa052200.64194419
79Phospholipase D signaling pathway_Homo sapiens_hsa040720.63245803
80Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.61883065
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.60885751
82Dilated cardiomyopathy_Homo sapiens_hsa054140.59984819
83Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59864042
84Dorso-ventral axis formation_Homo sapiens_hsa043200.59849066
85PPAR signaling pathway_Homo sapiens_hsa033200.59421725
86Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57681774
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57635522
88Regulation of actin cytoskeleton_Homo sapiens_hsa048100.55512136
89Choline metabolism in cancer_Homo sapiens_hsa052310.54583097
90Glioma_Homo sapiens_hsa052140.53755844
91Colorectal cancer_Homo sapiens_hsa052100.53359502
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52811242
93Thyroid cancer_Homo sapiens_hsa052160.52734805
94MAPK signaling pathway_Homo sapiens_hsa040100.50474886
95Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48261840
96Proteoglycans in cancer_Homo sapiens_hsa052050.48146217
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.48122819
98ABC transporters_Homo sapiens_hsa020100.48076290
99Pathways in cancer_Homo sapiens_hsa052000.47843554
100ErbB signaling pathway_Homo sapiens_hsa040120.47570019
101Ras signaling pathway_Homo sapiens_hsa040140.47543247
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.46702504
103GnRH signaling pathway_Homo sapiens_hsa049120.44340693
104Neurotrophin signaling pathway_Homo sapiens_hsa047220.43803300
105Adherens junction_Homo sapiens_hsa045200.43310339
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.42996362
107Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42207665
108Prion diseases_Homo sapiens_hsa050200.39903129
109VEGF signaling pathway_Homo sapiens_hsa043700.37860000
110Renal cell carcinoma_Homo sapiens_hsa052110.33010436
111Epstein-Barr virus infection_Homo sapiens_hsa051690.31610613
112Viral carcinogenesis_Homo sapiens_hsa052030.31178828
113HTLV-I infection_Homo sapiens_hsa051660.30336907
114Rap1 signaling pathway_Homo sapiens_hsa040150.28551555
115Endocytosis_Homo sapiens_hsa041440.28159298
116Fatty acid biosynthesis_Homo sapiens_hsa000610.28005748
117Renin-angiotensin system_Homo sapiens_hsa046140.27790479
118Sphingolipid metabolism_Homo sapiens_hsa006000.26993204
119MicroRNAs in cancer_Homo sapiens_hsa052060.26792887

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