SLIRP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)8.20439447
2ATP synthesis coupled proton transport (GO:0015986)7.88858429
3energy coupled proton transport, down electrochemical gradient (GO:0015985)7.88858429
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)7.49279816
5ribosomal small subunit biogenesis (GO:0042274)7.08402383
6viral transcription (GO:0019083)6.74405780
7respiratory electron transport chain (GO:0022904)6.58922491
8translational termination (GO:0006415)6.50825036
9electron transport chain (GO:0022900)6.40776045
10cotranslational protein targeting to membrane (GO:0006613)5.92846372
11SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.84772864
12protein targeting to ER (GO:0045047)5.83571772
13establishment of protein localization to endoplasmic reticulum (GO:0072599)5.58750967
14protein localization to endoplasmic reticulum (GO:0070972)5.56424151
15ribosomal small subunit assembly (GO:0000028)5.46524558
16protein neddylation (GO:0045116)5.36460971
17ribosomal large subunit biogenesis (GO:0042273)5.31352669
18translational elongation (GO:0006414)5.24179904
19maturation of SSU-rRNA (GO:0030490)5.11840670
20cellular protein complex disassembly (GO:0043624)5.11481451
21viral life cycle (GO:0019058)5.11153577
22mitochondrial respiratory chain complex I biogenesis (GO:0097031)5.08609984
23mitochondrial respiratory chain complex I assembly (GO:0032981)5.08609984
24NADH dehydrogenase complex assembly (GO:0010257)5.08609984
25GTP biosynthetic process (GO:0006183)5.08466326
26protein complex biogenesis (GO:0070271)4.95856134
27establishment of protein localization to mitochondrial membrane (GO:0090151)4.84003862
28proteasome assembly (GO:0043248)4.70676629
29central nervous system myelination (GO:0022010)4.68609878
30axon ensheathment in central nervous system (GO:0032291)4.68609878
31chaperone-mediated protein transport (GO:0072321)4.65303427
32nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.63150138
33translational initiation (GO:0006413)4.54459743
34mitochondrial respiratory chain complex assembly (GO:0033108)4.52944147
35chromatin remodeling at centromere (GO:0031055)4.41840625
36UTP biosynthetic process (GO:0006228)4.30057846
37translation (GO:0006412)4.29491168
38termination of RNA polymerase III transcription (GO:0006386)4.29167369
39transcription elongation from RNA polymerase III promoter (GO:0006385)4.29167369
40CENP-A containing nucleosome assembly (GO:0034080)4.27626876
41rRNA modification (GO:0000154)4.23433390
42protein complex disassembly (GO:0043241)4.17600896
43pseudouridine synthesis (GO:0001522)4.13123469
44macromolecular complex disassembly (GO:0032984)3.99591454
45purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.99221211
46purine nucleoside triphosphate biosynthetic process (GO:0009145)3.88856695
47protein targeting to membrane (GO:0006612)3.84815780
48hydrogen ion transmembrane transport (GO:1902600)3.80341229
49regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.71517770
50regulation of mitochondrial translation (GO:0070129)3.71412015
51ATP biosynthetic process (GO:0006754)3.68008321
52protein targeting to mitochondrion (GO:0006626)3.67044483
53UTP metabolic process (GO:0046051)3.62204043
54CTP metabolic process (GO:0046036)3.56784529
55CTP biosynthetic process (GO:0006241)3.56784529
56establishment of protein localization to mitochondrion (GO:0072655)3.55475507
57guanosine-containing compound biosynthetic process (GO:1901070)3.53551562
58rRNA metabolic process (GO:0016072)3.53028876
59ribonucleoside triphosphate biosynthetic process (GO:0009201)3.50424954
60histone exchange (GO:0043486)3.49368027
61anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.49320438
62kinetochore assembly (GO:0051382)3.47777952
63water-soluble vitamin biosynthetic process (GO:0042364)3.45111381
64cellular component biogenesis (GO:0044085)3.42227714
65rRNA methylation (GO:0031167)3.40695690
66proton transport (GO:0015992)3.39867175
67RNA capping (GO:0036260)3.39110412
687-methylguanosine RNA capping (GO:0009452)3.39110412
69DNA replication checkpoint (GO:0000076)3.38335973
707-methylguanosine mRNA capping (GO:0006370)3.37085391
71establishment of integrated proviral latency (GO:0075713)3.33854684
72kinetochore organization (GO:0051383)3.33047391
73regulation of mitotic spindle checkpoint (GO:1903504)3.32527878
74regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.32527878
75RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.32359601
76tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.32359601
77ribonucleoprotein complex biogenesis (GO:0022613)3.31626832
78protein localization to mitochondrion (GO:0070585)3.31383540
79hydrogen transport (GO:0006818)3.30974381
80fatty acid elongation (GO:0030497)3.29927188
81pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.29340318
82respiratory chain complex IV assembly (GO:0008535)3.27170410
83peptidyl-histidine modification (GO:0018202)3.26176397
84establishment of viral latency (GO:0019043)3.25704646
85DNA replication-independent nucleosome assembly (GO:0006336)3.25578638
86DNA replication-independent nucleosome organization (GO:0034724)3.25578638
87nuclear-transcribed mRNA catabolic process (GO:0000956)3.20292610
88negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.18694211
89inner mitochondrial membrane organization (GO:0007007)3.17337433
90DNA damage response, detection of DNA damage (GO:0042769)3.16338747
91maturation of 5.8S rRNA (GO:0000460)3.14316240
92histone mRNA metabolic process (GO:0008334)3.13153049
93positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.13127011
94nucleoside diphosphate phosphorylation (GO:0006165)3.13065757
95regulation of cellular amino acid metabolic process (GO:0006521)3.12159389
96protein-cofactor linkage (GO:0018065)3.11955028
97pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.09397097
98purine nucleobase biosynthetic process (GO:0009113)3.08820184
99nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.08025187
100pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.06505561
101L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.05566701
102cullin deneddylation (GO:0010388)3.04886524
103transcription elongation from RNA polymerase I promoter (GO:0006362)3.04081445
104nucleoside triphosphate biosynthetic process (GO:0009142)3.02367578
105mRNA catabolic process (GO:0006402)3.01965509
106negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.98241256
107negative regulation of ligase activity (GO:0051352)2.98241256
108exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.95019805
109cytochrome complex assembly (GO:0017004)2.94613649
110antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.93873111
111DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.91591408
112rRNA processing (GO:0006364)2.90772914
113protein targeting (GO:0006605)2.87825759
114oxidative phosphorylation (GO:0006119)2.87755393
115positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.85574735
116GPI anchor biosynthetic process (GO:0006506)2.84987119
117intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.84346753
118signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.84346753
119spliceosomal complex assembly (GO:0000245)2.82364462
120pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.82089958
121mitochondrial transport (GO:0006839)2.80578751
122signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.80024741
123signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.80024741
124signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.80024741
125intracellular protein transmembrane import (GO:0044743)2.79959362
126spliceosomal snRNP assembly (GO:0000387)2.79543091

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat6.03351144
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.51012147
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.20255481
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.18408733
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.08631058
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.80253483
7E2F7_22180533_ChIP-Seq_HELA_Human3.61543985
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.16737608
9CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.15206272
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.13622727
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.99858812
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.97710954
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.97079088
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.74997807
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.61814265
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.48700812
17ELK1_19687146_ChIP-ChIP_HELA_Human2.17994227
18MYC_18358816_ChIP-ChIP_MESCs_Mouse2.08449817
19DCP1A_22483619_ChIP-Seq_HELA_Human2.06835711
20VDR_23849224_ChIP-Seq_CD4+_Human2.05939885
21VDR_22108803_ChIP-Seq_LS180_Human2.03879392
22PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.00265832
23MYC_19079543_ChIP-ChIP_MESCs_Mouse1.98448847
24TAF15_26573619_Chip-Seq_HEK293_Human1.82745678
25TTF2_22483619_ChIP-Seq_HELA_Human1.81756878
26* SRF_21415370_ChIP-Seq_HL-1_Mouse1.81457849
27MYC_19030024_ChIP-ChIP_MESCs_Mouse1.81183545
28XRN2_22483619_ChIP-Seq_HELA_Human1.74209710
29FUS_26573619_Chip-Seq_HEK293_Human1.69633957
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69585825
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.67983227
32EZH2_22144423_ChIP-Seq_EOC_Human1.67411859
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.66940863
34ELK1_22589737_ChIP-Seq_MCF10A_Human1.65938589
35BP1_19119308_ChIP-ChIP_Hs578T_Human1.65137981
36CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.64788881
37E2F1_18555785_ChIP-Seq_MESCs_Mouse1.64368926
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60958980
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.60892137
40EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.60614280
41THAP11_20581084_ChIP-Seq_MESCs_Mouse1.60505650
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.58808965
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.58634305
44GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51446436
45IRF1_19129219_ChIP-ChIP_H3396_Human1.51260192
46FOXP3_21729870_ChIP-Seq_TREG_Human1.51221734
47TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.50480747
48CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.49932824
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49781711
50MYC_18940864_ChIP-ChIP_HL60_Human1.48371297
51E2F1_21310950_ChIP-Seq_MCF-7_Human1.43940369
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.41396542
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.32342184
54HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.31796265
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.31665223
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.31266183
57ER_23166858_ChIP-Seq_MCF-7_Human1.31009495
58EWS_26573619_Chip-Seq_HEK293_Human1.29748222
59FOXM1_23109430_ChIP-Seq_U2OS_Human1.29127940
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.28523759
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.28268769
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.27141445
63POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27073071
64NANOG_16153702_ChIP-ChIP_HESCs_Human1.23548966
65GBX2_23144817_ChIP-Seq_PC3_Human1.22026502
66DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.21387847
67NANOG_18555785_ChIP-Seq_MESCs_Mouse1.17347223
68CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17260707
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16245815
70HOXB4_20404135_ChIP-ChIP_EML_Mouse1.15870590
71ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.15711697
72RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13072939
73IGF1R_20145208_ChIP-Seq_DFB_Human1.11976639
74POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.09812901
75E2F4_17652178_ChIP-ChIP_JURKAT_Human1.09317754
76AR_21909140_ChIP-Seq_LNCAP_Human1.09288389
77KDM5A_27292631_Chip-Seq_BREAST_Human1.08568609
78ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.06085859
79BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05954554
80CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.04278814
81CTBP2_25329375_ChIP-Seq_LNCAP_Human1.04247191
82E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03691338
83NELFA_20434984_ChIP-Seq_ESCs_Mouse1.03065937
84SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02881876
85TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.02803226
86ZFX_18555785_ChIP-Seq_MESCs_Mouse1.02265907
87P300_19829295_ChIP-Seq_ESCs_Human1.01099091
88KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00925760
89SOX17_20123909_ChIP-Seq_XEN_Mouse1.00146558
90GABP_19822575_ChIP-Seq_HepG2_Human1.00074411
91POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.99910190
92MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.97338543
93FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.96715955
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.95938621
95ZNF274_21170338_ChIP-Seq_K562_Hela0.94316307
96NOTCH1_21737748_ChIP-Seq_TLL_Human0.92596022
97RNF2_27304074_Chip-Seq_NSC_Mouse0.91265839
98CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.89174236
99PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.88966685
100SOX2_16153702_ChIP-ChIP_HESCs_Human0.88453986
101CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.88245238
102YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.88047114
103KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.86997242
104PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.86996626
105MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.86580075
106FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.86351767
107EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.85780882
108PADI4_21655091_ChIP-ChIP_MCF-7_Human0.85705931
109EZH2_27304074_Chip-Seq_ESCs_Mouse0.85052328
110POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.83423392
111CTCF_18555785_ChIP-Seq_MESCs_Mouse0.83190515
112NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.82664378
113SUZ12_18555785_Chip-Seq_ESCs_Mouse0.82185985
114JARID2_20064375_ChIP-Seq_MESCs_Mouse0.82137830
115EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.82028290
116ERG_20887958_ChIP-Seq_HPC-7_Mouse0.81617444
117MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.81353145
118P300_18555785_Chip-Seq_ESCs_Mouse0.79722341
119GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.79546936
120CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.79191173
121SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.78330874
122FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.77913530
123OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.77682959
124CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.77606592
125SUZ12_27294783_Chip-Seq_NPCs_Mouse0.76386813
126TOP2B_26459242_ChIP-Seq_MCF-7_Human0.75970149
127JUN_21703547_ChIP-Seq_K562_Human0.75967124
128STAT3_18555785_Chip-Seq_ESCs_Mouse0.75924747
129NANOG_18555785_Chip-Seq_ESCs_Mouse0.75889406
130SOX2_18692474_ChIP-Seq_MEFs_Mouse0.75359949
131TP53_22573176_ChIP-Seq_HFKS_Human0.74950184
132SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.72491429
133NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.71906046
134TP63_19390658_ChIP-ChIP_HaCaT_Human0.70120464
135ELF5_23300383_ChIP-Seq_T47D_Human0.69617519
136FOXP1_21924763_ChIP-Seq_HESCs_Human0.67908095
137SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.65163674

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.57365941
2MP0003136_yellow_coat_color3.96794767
3MP0003693_abnormal_embryo_hatching3.72413760
4MP0003880_abnormal_central_pattern3.70938281
5MP0001529_abnormal_vocalization3.51997162
6MP0008058_abnormal_DNA_repair3.49798592
7MP0010094_abnormal_chromosome_stability3.01642163
8MP0003941_abnormal_skin_development2.86376974
9MP0001905_abnormal_dopamine_level2.82052713
10MP0003111_abnormal_nucleus_morphology2.75127529
11MP0003806_abnormal_nucleotide_metabolis2.69207316
12MP0006276_abnormal_autonomic_nervous2.49381145
13MP0003077_abnormal_cell_cycle2.44802842
14MP0004142_abnormal_muscle_tone2.26278010
15MP0000372_irregular_coat_pigmentation2.21131234
16MP0002163_abnormal_gland_morphology2.20477824
17MP0008877_abnormal_DNA_methylation2.14698379
18MP0002102_abnormal_ear_morphology2.11858608
19MP0005409_darkened_coat_color2.11798824
20MP0002638_abnormal_pupillary_reflex2.11446072
21MP0004381_abnormal_hair_follicle2.07143729
22MP0008007_abnormal_cellular_replicative2.02946438
23MP0001293_anophthalmia2.01501466
24MP0001188_hyperpigmentation1.94461969
25MP0005171_absent_coat_pigmentation1.93358718
26MP0005379_endocrine/exocrine_gland_phen1.87129102
27MP0000920_abnormal_myelination1.86736040
28MP0003123_paternal_imprinting1.84852883
29MP0000566_synostosis1.83764332
30MP0001485_abnormal_pinna_reflex1.79039193
31MP0002277_abnormal_respiratory_mucosa1.77449564
32MP0006292_abnormal_olfactory_placode1.74201564
33MP0004742_abnormal_vestibular_system1.71076966
34MP0005423_abnormal_somatic_nervous1.70394583
35MP0006072_abnormal_retinal_apoptosis1.69108668
36MP0003186_abnormal_redox_activity1.57630948
37MP0008057_abnormal_DNA_replication1.56582981
38MP0001486_abnormal_startle_reflex1.55674098
39MP0003567_abnormal_fetal_cardiomyocyte1.55323781
40MP0002272_abnormal_nervous_system1.50762619
41MP0006036_abnormal_mitochondrial_physio1.50688758
42MP0001986_abnormal_taste_sensitivity1.49403997
43MP0002837_dystrophic_cardiac_calcinosis1.46336975
44MP0002938_white_spotting1.45898505
45MP0001440_abnormal_grooming_behavior1.43644310
46MP0003718_maternal_effect1.43215436
47MP0009046_muscle_twitch1.42092643
48MP0006035_abnormal_mitochondrial_morpho1.40964156
49MP0002160_abnormal_reproductive_system1.40290902
50MP0001968_abnormal_touch/_nociception1.35885764
51MP0002734_abnormal_mechanical_nocicepti1.33952127
52MP0003121_genomic_imprinting1.33637803
53MP0003011_delayed_dark_adaptation1.32865497
54MP0008932_abnormal_embryonic_tissue1.32604456
55MP0003938_abnormal_ear_development1.32122781
56MP0005084_abnormal_gallbladder_morpholo1.31273370
57MP0005551_abnormal_eye_electrophysiolog1.28562518
58MP0010030_abnormal_orbit_morphology1.26192780
59MP0002736_abnormal_nociception_after1.24877105
60MP0002064_seizures1.24723213
61MP0001727_abnormal_embryo_implantation1.21346263
62MP0000778_abnormal_nervous_system1.20025962
63MP0009745_abnormal_behavioral_response1.19148782
64MP0005410_abnormal_fertilization1.18558209
65MP0003950_abnormal_plasma_membrane1.16181659
66MP0005389_reproductive_system_phenotype1.16039957
67MP0009697_abnormal_copulation1.16025429
68MP0002210_abnormal_sex_determination1.15057304
69MP0000026_abnormal_inner_ear1.14973325
70MP0002148_abnormal_hypersensitivity_rea1.14569875
71MP0003315_abnormal_perineum_morphology1.13499098
72MP0001764_abnormal_homeostasis1.13141207
73MP0003724_increased_susceptibility_to1.12562687
74MP0008995_early_reproductive_senescence1.10746755
75MP0002132_abnormal_respiratory_system1.10663036
76MP0003937_abnormal_limbs/digits/tail_de1.10297721
77MP0001346_abnormal_lacrimal_gland1.09692733
78MP0005408_hypopigmentation1.07682975
79MP0001970_abnormal_pain_threshold1.06397650
80MP0000350_abnormal_cell_proliferation1.05452880
81MP0005253_abnormal_eye_physiology1.03729751
82MP0008872_abnormal_physiological_respon1.03413590
83MP0003890_abnormal_embryonic-extraembry1.01432668
84MP0002751_abnormal_autonomic_nervous1.01135350
85MP0001919_abnormal_reproductive_system1.00694442
86MP0003787_abnormal_imprinting1.00437476
87MP0002572_abnormal_emotion/affect_behav0.99784273
88MP0001963_abnormal_hearing_physiology0.99628967
89MP0002752_abnormal_somatic_nervous0.99561789
90MP0002067_abnormal_sensory_capabilities0.96239909
91MP0001145_abnormal_male_reproductive0.95963739
92MP0002234_abnormal_pharynx_morphology0.95609514
93MP0008004_abnormal_stomach_pH0.95163654
94MP0004924_abnormal_behavior0.94962263
95MP0005386_behavior/neurological_phenoty0.94962263
96MP0002254_reproductive_system_inflammat0.94578718
97MP0001697_abnormal_embryo_size0.94199148
98MP0004957_abnormal_blastocyst_morpholog0.91934862
99MP0008875_abnormal_xenobiotic_pharmacok0.91821016
100MP0002735_abnormal_chemical_nociception0.91377111
101MP0000049_abnormal_middle_ear0.91310744
102MP0000653_abnormal_sex_gland0.90740243
103MP0005499_abnormal_olfactory_system0.90357715
104MP0005394_taste/olfaction_phenotype0.90357715
105MP0004133_heterotaxia0.89191788
106MP0002332_abnormal_exercise_endurance0.89087876
107MP0001929_abnormal_gametogenesis0.87758530
108MP0009250_abnormal_appendicular_skeleto0.86957277
109MP0001730_embryonic_growth_arrest0.86744350
110MP0001286_abnormal_eye_development0.86079156
111MP0005332_abnormal_amino_acid0.84265898
112MP0002233_abnormal_nose_morphology0.84007227
113MP0010386_abnormal_urinary_bladder0.83501303
114MP0000358_abnormal_cell_content/0.82607272
115MP0002085_abnormal_embryonic_tissue0.81998651
116MP0000462_abnormal_digestive_system0.81662384
117MP0000762_abnormal_tongue_morphology0.81561474
118MP0002733_abnormal_thermal_nociception0.81160142
119MP0001542_abnormal_bone_strength0.80982622
120MP0005195_abnormal_posterior_eye0.80598795
121MP0002184_abnormal_innervation0.79797663
122MP0003137_abnormal_impulse_conducting0.78964122
123MP0000631_abnormal_neuroendocrine_gland0.78205726
124MP0004270_analgesia0.77857794
125MP0002229_neurodegeneration0.77830138
126MP0000313_abnormal_cell_death0.77501282
127MP0002697_abnormal_eye_size0.77256849
128MP0004215_abnormal_myocardial_fiber0.76489829
129MP0003786_premature_aging0.76340044
130MP0003195_calcinosis0.76101679
131MP0002090_abnormal_vision0.75125193
132MP0005174_abnormal_tail_pigmentation0.74304464
133MP0004145_abnormal_muscle_electrophysio0.72438329
134MP0002111_abnormal_tail_morphology0.72311546
135MP0005645_abnormal_hypothalamus_physiol0.71880819
136MP0003698_abnormal_male_reproductive0.69525904
137MP0003119_abnormal_digestive_system0.67422560
138MP0005646_abnormal_pituitary_gland0.66872379
139MP0008789_abnormal_olfactory_epithelium0.66672624
140MP0002095_abnormal_skin_pigmentation0.66522751
141MP0003122_maternal_imprinting0.66077370
142MP0002066_abnormal_motor_capabilities/c0.64543472
143MP0000749_muscle_degeneration0.64447367
144MP0001984_abnormal_olfaction0.64269129
145MP0002557_abnormal_social/conspecific_i0.64137432
146MP0002882_abnormal_neuron_morphology0.63991997
147MP0001501_abnormal_sleep_pattern0.63907597
148MP0003634_abnormal_glial_cell0.63679945
149MP0003635_abnormal_synaptic_transmissio0.63141058
150MP0004134_abnormal_chest_morphology0.62571479
151MP0004147_increased_porphyrin_level0.61943629
152MP0002295_abnormal_pulmonary_circulatio0.60943601

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.84545829
2Mitochondrial inheritance (HP:0001427)6.12816728
3Abnormal mitochondria in muscle tissue (HP:0008316)6.02070262
4Progressive macrocephaly (HP:0004481)5.81718797
5Increased hepatocellular lipid droplets (HP:0006565)5.54871753
6Acute encephalopathy (HP:0006846)5.41771890
7Increased CSF lactate (HP:0002490)5.06563887
8Renal Fanconi syndrome (HP:0001994)4.97303237
9Hepatocellular necrosis (HP:0001404)4.95603108
10Lipid accumulation in hepatocytes (HP:0006561)4.82775626
11Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.48653795
12Abnormality of cells of the erythroid lineage (HP:0012130)4.40556944
13Hepatic necrosis (HP:0002605)4.16831156
14Muscle abnormality related to mitochondrial dysfunction (HP:0003800)4.09211127
15Reticulocytopenia (HP:0001896)4.07902793
16Parakeratosis (HP:0001036)4.03737227
173-Methylglutaconic aciduria (HP:0003535)4.02223239
18Abnormal number of erythroid precursors (HP:0012131)3.89171228
19Exertional dyspnea (HP:0002875)3.81922628
20Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.78672444
21Macrocytic anemia (HP:0001972)3.78320514
22Optic disc pallor (HP:0000543)3.78311500
23Increased intramyocellular lipid droplets (HP:0012240)3.76318569
24Cerebral edema (HP:0002181)3.61837586
25Abnormality of glycolysis (HP:0004366)3.56390738
26Increased serum pyruvate (HP:0003542)3.56390738
27Leukodystrophy (HP:0002415)3.55730660
28Exercise intolerance (HP:0003546)3.53044240
29Respiratory failure (HP:0002878)3.51602357
30Decreased activity of mitochondrial respiratory chain (HP:0008972)3.48576011
31Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.48576011
32Abnormality of renal resorption (HP:0011038)3.28420448
33Increased serum lactate (HP:0002151)3.18093105
34Pallor (HP:0000980)3.12411019
35Colon cancer (HP:0003003)3.06774497
36Increased muscle lipid content (HP:0009058)3.04713983
37Aplastic anemia (HP:0001915)3.01342684
38Lactic acidosis (HP:0003128)2.99577450
39Respiratory difficulties (HP:0002880)2.88979108
40Oral leukoplakia (HP:0002745)2.85710392
41Aplasia/Hypoplasia of the sacrum (HP:0008517)2.84541704
42Congenital ichthyosiform erythroderma (HP:0007431)2.71996312
43Abnormal hemoglobin (HP:0011902)2.71066272
44Abnormality of methionine metabolism (HP:0010901)2.47848527
45Hyperphosphaturia (HP:0003109)2.35574178
46Amniotic constriction ring (HP:0009775)2.33527611
47Abnormality of placental membranes (HP:0011409)2.33527611
48Pancreatic fibrosis (HP:0100732)2.29206545
49Concave nail (HP:0001598)2.27260912
50Microvesicular hepatic steatosis (HP:0001414)2.27236284
51Abnormality of serum amino acid levels (HP:0003112)2.26775826
52X-linked dominant inheritance (HP:0001423)2.26528518
53Hyperglycinemia (HP:0002154)2.23854127
54Megaloblastic anemia (HP:0001889)2.22511173
55Abnormality of the axillary hair (HP:0100134)2.22081780
56Abnormality of secondary sexual hair (HP:0009888)2.22081780
57Meckel diverticulum (HP:0002245)2.19446532
58Abnormal ciliary motility (HP:0012262)2.18496716
59Type I transferrin isoform profile (HP:0003642)2.18465754
60Abnormality of the labia minora (HP:0012880)2.17733258
61Aplasia/hypoplasia of the uterus (HP:0008684)2.13905769
62Abnormal respiratory epithelium morphology (HP:0012253)2.13521892
63Abnormal respiratory motile cilium morphology (HP:0005938)2.13521892
64Glycosuria (HP:0003076)2.13018167
65Abnormality of urine glucose concentration (HP:0011016)2.13018167
66Pancreatic cysts (HP:0001737)2.12515793
67Sensory axonal neuropathy (HP:0003390)2.11652630
68Abnormality of aspartate family amino acid metabolism (HP:0010899)2.11509136
69Abnormality of the ileum (HP:0001549)2.08243840
70Medial flaring of the eyebrow (HP:0010747)2.07685912
71CNS demyelination (HP:0007305)2.07542570
72Abnormal pupillary function (HP:0007686)2.07263653
73Cerebral hypomyelination (HP:0006808)2.06653799
74Abnormality of alanine metabolism (HP:0010916)2.04255992
75Hyperalaninemia (HP:0003348)2.04255992
76Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.04255992
77Pancytopenia (HP:0001876)2.03768011
78Multiple enchondromatosis (HP:0005701)2.02804395
79Degeneration of the lateral corticospinal tracts (HP:0002314)2.00897976
80Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.00897976
81Absent thumb (HP:0009777)2.00624543
82Abnormality of homocysteine metabolism (HP:0010919)1.97197121
83Homocystinuria (HP:0002156)1.97197121
84Hypothermia (HP:0002045)1.96636463
85Sparse eyelashes (HP:0000653)1.96106249
86Pendular nystagmus (HP:0012043)1.95756339
87Sclerocornea (HP:0000647)1.94953722
88Abnormal urine phosphate concentration (HP:0012599)1.94810114
89Dynein arm defect of respiratory motile cilia (HP:0012255)1.94576836
90Absent/shortened dynein arms (HP:0200106)1.94576836
91Birth length less than 3rd percentile (HP:0003561)1.93860877
92Cleft eyelid (HP:0000625)1.93141492
93Emotional lability (HP:0000712)1.92825052
94Stenosis of the external auditory canal (HP:0000402)1.89318702
95Renal tubular dysfunction (HP:0000124)1.88681036
96Congenital, generalized hypertrichosis (HP:0004540)1.88386432
97Abnormality of midbrain morphology (HP:0002418)1.88246888
98Molar tooth sign on MRI (HP:0002419)1.88246888
99Aplasia/Hypoplasia of the uvula (HP:0010293)1.87800752
100True hermaphroditism (HP:0010459)1.84940237
101Abnormality of the preputium (HP:0100587)1.83357780
102Abnormal lung lobation (HP:0002101)1.82229600
103Hypoplasia of the uterus (HP:0000013)1.81212157
104Abnormality of the septum pellucidum (HP:0007375)1.80554170
105Abnormal number of incisors (HP:0011064)1.80388396
106Hypoplastic pelvis (HP:0008839)1.79820691
107Degeneration of anterior horn cells (HP:0002398)1.79047755
108Abnormality of the anterior horn cell (HP:0006802)1.79047755
109Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.78864839
110Abnormal protein N-linked glycosylation (HP:0012347)1.78864839
111Abnormal protein glycosylation (HP:0012346)1.78864839
112Abnormal glycosylation (HP:0012345)1.78864839
113Abnormal respiratory motile cilium physiology (HP:0012261)1.77744704
114Partial duplication of thumb phalanx (HP:0009944)1.77519190
115Reduced antithrombin III activity (HP:0001976)1.77289148
116Abnormality of chromosome stability (HP:0003220)1.76379411
117Congenital sensorineural hearing impairment (HP:0008527)1.75360458
118Hypoplastic left heart (HP:0004383)1.75344846
119Gait imbalance (HP:0002141)1.73167317
120Nasolacrimal duct obstruction (HP:0000579)1.72275337
121Congenital primary aphakia (HP:0007707)1.72085839
122Abnormality of the vitamin B12 metabolism (HP:0004341)1.71095758
123Generalized aminoaciduria (HP:0002909)1.70948086
124Progressive external ophthalmoplegia (HP:0000590)1.70880141
125Hypoplasia of the pons (HP:0012110)1.68692432
126Methylmalonic acidemia (HP:0002912)1.67753669
127Chromsome breakage (HP:0040012)1.67497569
128Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.66301077
129Dicarboxylic aciduria (HP:0003215)1.65982556
130Adrenal hypoplasia (HP:0000835)1.65772824
131Partial duplication of the phalanx of hand (HP:0009999)1.64592979
132Blindness (HP:0000618)1.62009837
133Absent septum pellucidum (HP:0001331)1.60773135
134Patchy hypopigmentation of hair (HP:0011365)1.60509044
135Nephrogenic diabetes insipidus (HP:0009806)1.60413774
136Triphalangeal thumb (HP:0001199)1.60302186
137Vaginal atresia (HP:0000148)1.58272809
138Lethargy (HP:0001254)1.57290811
139Retinal dysplasia (HP:0007973)1.56388838
140Rough bone trabeculation (HP:0100670)1.54809890
141Breast hypoplasia (HP:0003187)1.52213681
142Asplenia (HP:0001746)1.52213653
143Genital tract atresia (HP:0001827)1.51636571
144Hypoplastic heart (HP:0001961)1.50199449
145Methylmalonic aciduria (HP:0012120)1.46607773
146Neuroendocrine neoplasm (HP:0100634)1.45043793
147Septo-optic dysplasia (HP:0100842)1.44957940

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.68063514
2PBK3.80528946
3CDC73.55081755
4STK393.35628659
5NME23.33417773
6STK163.19310279
7TLK13.18349397
8BUB12.63013876
9TAF12.60657907
10NME12.49116244
11MST42.39173320
12EIF2AK12.39142739
13CASK2.31343885
14TNIK2.26468265
15VRK12.14602054
16GRK72.13505832
17CDK192.11571471
18OXSR12.10057126
19NUAK12.04894812
20NEK11.99102740
21TTK1.91570421
22BMPR1B1.89641336
23PNCK1.86076019
24SRPK11.84976546
25BCR1.78618141
26MUSK1.61542633
27WEE11.52505960
28WNK41.46496991
29TESK21.44655559
30MAP3K121.39472862
31IRAK21.35602184
32ARAF1.33882146
33DYRK21.29376383
34EIF2AK31.28436320
35MAPKAPK51.27052072
36PDK21.26122311
37IRAK31.24595680
38IRAK11.23790930
39MKNK11.23331084
40BCKDK1.21739816
41BRSK21.20696821
42PIM21.17947135
43IRAK41.15288410
44PKN11.12867636
45ADRBK21.10773291
46LIMK11.07544180
47CHEK21.07325038
48MAP4K21.06894507
49UHMK11.05868039
50MKNK21.04853658
51CAMK2B0.97768287
52ABL20.93806648
53EIF2AK20.92321421
54DYRK30.89206362
55FGR0.88199973
56CSNK1G30.88174430
57PLK40.87430219
58RPS6KA50.87041152
59MAP2K70.85648032
60BMPR20.83558375
61MAPK130.82982011
62MYLK0.82629531
63ATR0.80479360
64STK40.79609644
65BRAF0.78912194
66YES10.76936849
67CAMK2D0.76844398
68BRSK10.76249938
69AURKA0.75207339
70ADRBK10.74739168
71TSSK60.73426508
72CDK80.67247533
73OBSCN0.66365403
74MARK10.65959705
75WNK30.65106984
76TRIM280.64292040
77GRK50.63938774
78CAMK2A0.63481351
79BLK0.62475082
80CAMK2G0.62340636
81MAPK150.60825699
82PINK10.59864958
83CSNK2A10.57501304
84CSNK2A20.56526403
85DAPK10.56176861
86PRKCG0.56111704
87CSNK1G10.55194468
88CSNK1E0.54786752
89NEK60.54701993
90CHEK10.54319657
91NEK20.51956210
92FES0.50789810
93ROCK20.49545226
94ATM0.48328588
95MET0.47703821
96DAPK30.47669505
97KDR0.45892161
98PRKCE0.43767149
99ALK0.43007543
100INSRR0.42807488
101CDK140.42333908
102CSNK1G20.41179542
103PRKACA0.40334655
104PLK20.40320311
105PAK40.39355724
106RPS6KB20.38595927
107CSNK1A10.38084046
108ILK0.36989953
109MOS0.36782175
110MST1R0.36730870
111CDK30.36589185
112PRKCI0.36078552
113CDK11A0.35900045
114PAK10.35197701
115TIE10.34750470
116TEC0.34008008
117CSNK1A1L0.33988948
118CLK10.33275405
119STK38L0.32328423
120ACVR1B0.31623463
121RIPK40.30952729
122IKBKB0.30738874
123PIK3CG0.30525611
124CDK70.30379162
125ZAK0.29740075
126PLK10.29718172
127CDK150.29563483
128MAPK40.29242216
129CDK10.29241978
130GRK10.28610745
131CDK180.28570645
132AURKB0.28071700
133PLK30.27530540
134PRKDC0.27110144
135PHKG20.27072125
136PHKG10.27072125
137PRKCQ0.26503321
138ERBB40.25977842
139LYN0.25802662
140RPS6KA40.24889844
141CDK20.24644359
142PRKACB0.23970806

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.68039089
2Ribosome_Homo sapiens_hsa030105.62417813
3Parkinsons disease_Homo sapiens_hsa050124.80394351
4Proteasome_Homo sapiens_hsa030503.70693780
5Alzheimers disease_Homo sapiens_hsa050103.62690151
6Huntingtons disease_Homo sapiens_hsa050163.59764983
7Protein export_Homo sapiens_hsa030603.30210249
8RNA polymerase_Homo sapiens_hsa030203.23597902
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.03811429
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.44730911
11Cardiac muscle contraction_Homo sapiens_hsa042602.19619145
12Pyrimidine metabolism_Homo sapiens_hsa002401.71276011
13Fatty acid elongation_Homo sapiens_hsa000621.67505800
14Spliceosome_Homo sapiens_hsa030401.60722038
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.59096695
16Homologous recombination_Homo sapiens_hsa034401.57513700
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.55745969
18Steroid biosynthesis_Homo sapiens_hsa001001.55110341
19Basal transcription factors_Homo sapiens_hsa030221.43305380
20Mismatch repair_Homo sapiens_hsa034301.41589074
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.38264795
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38080197
23Nucleotide excision repair_Homo sapiens_hsa034201.38030828
24Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.33694453
25DNA replication_Homo sapiens_hsa030301.31030551
26Ether lipid metabolism_Homo sapiens_hsa005651.28882407
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.27414405
28Collecting duct acid secretion_Homo sapiens_hsa049661.14876759
29Sulfur metabolism_Homo sapiens_hsa009201.01033540
30Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.99940753
31Purine metabolism_Homo sapiens_hsa002300.99915980
32Selenocompound metabolism_Homo sapiens_hsa004500.96860030
33Arachidonic acid metabolism_Homo sapiens_hsa005900.91426448
34Glutathione metabolism_Homo sapiens_hsa004800.88348669
35SNARE interactions in vesicular transport_Homo sapiens_hsa041300.87612538
36Vibrio cholerae infection_Homo sapiens_hsa051100.86782906
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.85744076
38Graft-versus-host disease_Homo sapiens_hsa053320.83317581
39Rheumatoid arthritis_Homo sapiens_hsa053230.82765466
40RNA degradation_Homo sapiens_hsa030180.82671642
41Phototransduction_Homo sapiens_hsa047440.81970517
42Linoleic acid metabolism_Homo sapiens_hsa005910.80769125
43Fanconi anemia pathway_Homo sapiens_hsa034600.80439097
44Folate biosynthesis_Homo sapiens_hsa007900.77867575
45Metabolic pathways_Homo sapiens_hsa011000.76865764
46Non-homologous end-joining_Homo sapiens_hsa034500.76589592
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.76250435
48Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75356725
49RNA transport_Homo sapiens_hsa030130.73394555
50Autoimmune thyroid disease_Homo sapiens_hsa053200.71384066
51Sphingolipid metabolism_Homo sapiens_hsa006000.70875300
52Allograft rejection_Homo sapiens_hsa053300.70049793
53Vitamin digestion and absorption_Homo sapiens_hsa049770.67321388
54Nicotine addiction_Homo sapiens_hsa050330.66934895
55Serotonergic synapse_Homo sapiens_hsa047260.65755300
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65157542
57Systemic lupus erythematosus_Homo sapiens_hsa053220.61431012
58mRNA surveillance pathway_Homo sapiens_hsa030150.54467907
59Carbon metabolism_Homo sapiens_hsa012000.54067081
60Sulfur relay system_Homo sapiens_hsa041220.53967368
61Tyrosine metabolism_Homo sapiens_hsa003500.52539112
62Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.50643780
63alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.50369153
64Drug metabolism - other enzymes_Homo sapiens_hsa009830.49526489
65Base excision repair_Homo sapiens_hsa034100.48915566
66Asthma_Homo sapiens_hsa053100.48682620
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47031186
68Biosynthesis of amino acids_Homo sapiens_hsa012300.46594697
692-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.46458728
70Caffeine metabolism_Homo sapiens_hsa002320.43382126
71Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.43361188
72Oocyte meiosis_Homo sapiens_hsa041140.42496251
73Tryptophan metabolism_Homo sapiens_hsa003800.42381989
74Epstein-Barr virus infection_Homo sapiens_hsa051690.41881659
75beta-Alanine metabolism_Homo sapiens_hsa004100.41488643
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.40580627
77Fatty acid degradation_Homo sapiens_hsa000710.39765568
78p53 signaling pathway_Homo sapiens_hsa041150.39686368
79Phagosome_Homo sapiens_hsa041450.38230753
80Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36148193
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.36115415
82Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.36112169
83Type I diabetes mellitus_Homo sapiens_hsa049400.35572723
84Alcoholism_Homo sapiens_hsa050340.34852562
85African trypanosomiasis_Homo sapiens_hsa051430.34713485
86Nitrogen metabolism_Homo sapiens_hsa009100.34123802
87Histidine metabolism_Homo sapiens_hsa003400.33576560
88Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.33384818
89Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.32878242
90Arginine and proline metabolism_Homo sapiens_hsa003300.31598041
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30150641
92Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27086668
93Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.26941700
94N-Glycan biosynthesis_Homo sapiens_hsa005100.24962167
95Phenylalanine metabolism_Homo sapiens_hsa003600.24711512
96Fatty acid metabolism_Homo sapiens_hsa012120.24647830
97Malaria_Homo sapiens_hsa051440.23607684
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.23388372
99Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.22613270
100Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.22548972
101Basal cell carcinoma_Homo sapiens_hsa052170.22253353
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.21978515
103Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.20309025
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.19443710
105GABAergic synapse_Homo sapiens_hsa047270.19404717
106Taste transduction_Homo sapiens_hsa047420.19108140
107Long-term depression_Homo sapiens_hsa047300.18877354
108Fat digestion and absorption_Homo sapiens_hsa049750.17671869
109Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.17342601
110One carbon pool by folate_Homo sapiens_hsa006700.16643753
111Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.14403861
112Glutamatergic synapse_Homo sapiens_hsa047240.14033874
113Chemical carcinogenesis_Homo sapiens_hsa052040.13899915
114Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.13162605
115Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.12673701
116Hedgehog signaling pathway_Homo sapiens_hsa043400.11720613
117Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.11621758
118Retinol metabolism_Homo sapiens_hsa008300.11483672
119Pyruvate metabolism_Homo sapiens_hsa006200.10810469
120Axon guidance_Homo sapiens_hsa043600.10705816
121NOD-like receptor signaling pathway_Homo sapiens_hsa046210.10475905
122Peroxisome_Homo sapiens_hsa041460.10077164
123Mineral absorption_Homo sapiens_hsa049780.09720738
124Regulation of autophagy_Homo sapiens_hsa041400.09404445
125Morphine addiction_Homo sapiens_hsa050320.09353323
126Butanoate metabolism_Homo sapiens_hsa006500.09288790
127Intestinal immune network for IgA production_Homo sapiens_hsa046720.07072996
128Pertussis_Homo sapiens_hsa051330.05359206
129Propanoate metabolism_Homo sapiens_hsa006400.05247938
130Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.05193330
131Vitamin B6 metabolism_Homo sapiens_hsa007500.04860659
132Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.04391926
133Cysteine and methionine metabolism_Homo sapiens_hsa002700.04321263
134Cell cycle_Homo sapiens_hsa041100.02887692

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »