SMARCA5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.10097966
2nuclear pore organization (GO:0006999)5.94711449
3protein localization to kinetochore (GO:0034501)5.03753959
4establishment of integrated proviral latency (GO:0075713)4.89761344
5pore complex assembly (GO:0046931)4.66399170
6DNA unwinding involved in DNA replication (GO:0006268)4.47799245
7mitotic sister chromatid cohesion (GO:0007064)4.45664079
8regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.33372810
9mitotic chromosome condensation (GO:0007076)4.26196611
10mitotic metaphase plate congression (GO:0007080)4.23675638
11protein localization to chromosome, centromeric region (GO:0071459)4.21031884
12kinetochore organization (GO:0051383)4.09092109
13mitotic nuclear envelope disassembly (GO:0007077)4.07840188
14regulation of RNA export from nucleus (GO:0046831)3.93459776
15DNA replication initiation (GO:0006270)3.92003704
16DNA replication-dependent nucleosome organization (GO:0034723)3.90710676
17DNA replication-dependent nucleosome assembly (GO:0006335)3.90710676
18non-recombinational repair (GO:0000726)3.89866853
19double-strand break repair via nonhomologous end joining (GO:0006303)3.89866853
20paraxial mesoderm development (GO:0048339)3.87756768
21metaphase plate congression (GO:0051310)3.85047963
22nuclear envelope disassembly (GO:0051081)3.84940555
23membrane disassembly (GO:0030397)3.84940555
24positive regulation of chromosome segregation (GO:0051984)3.82937306
25DNA ligation (GO:0006266)3.77851178
26regulation of histone H3-K9 methylation (GO:0051570)3.77165874
27positive regulation of mitotic sister chromatid separation (GO:1901970)3.76133245
28positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.76133245
29positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.76133245
30sister chromatid segregation (GO:0000819)3.74288080
31regulation of spindle organization (GO:0090224)3.71688359
32attachment of spindle microtubules to kinetochore (GO:0008608)3.60971246
33establishment of viral latency (GO:0019043)3.60871059
34DNA replication checkpoint (GO:0000076)3.60601944
35regulation of helicase activity (GO:0051095)3.59054634
36DNA duplex unwinding (GO:0032508)3.59006360
37DNA geometric change (GO:0032392)3.57628466
38regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.55993866
39* chromatin remodeling at centromere (GO:0031055)3.55904537
40mitotic sister chromatid segregation (GO:0000070)3.55487852
41regulation of sister chromatid cohesion (GO:0007063)3.52811591
42meiotic chromosome segregation (GO:0045132)3.50798963
43DNA strand elongation involved in DNA replication (GO:0006271)3.49889277
44dosage compensation (GO:0007549)3.43497824
45IMP biosynthetic process (GO:0006188)3.43148588
46ribosome assembly (GO:0042255)3.42293444
47* CENP-A containing nucleosome assembly (GO:0034080)3.39958522
48regulation of mitotic spindle organization (GO:0060236)3.39244614
49* DNA replication-independent nucleosome assembly (GO:0006336)3.39191559
50* DNA replication-independent nucleosome organization (GO:0034724)3.39191559
51protein localization to chromosome (GO:0034502)3.38124161
52establishment of chromosome localization (GO:0051303)3.37682556
53spindle checkpoint (GO:0031577)3.37490166
54negative regulation of histone methylation (GO:0031061)3.37366284
55regulation of centriole replication (GO:0046599)3.35635963
56DNA strand elongation (GO:0022616)3.32286039
57heterochromatin organization (GO:0070828)3.31435345
58mitotic recombination (GO:0006312)3.31406001
59regulation of centrosome cycle (GO:0046605)3.26265624
60regulation of chromosome segregation (GO:0051983)3.25278769
61regulation of mitotic metaphase/anaphase transition (GO:0030071)3.25169335
62regulation of DNA endoreduplication (GO:0032875)3.24975288
63DNA topological change (GO:0006265)3.23008030
64kinetochore assembly (GO:0051382)3.21201191
65mitotic spindle checkpoint (GO:0071174)3.20431767
66nucleobase biosynthetic process (GO:0046112)3.19058033
67* chromatin assembly or disassembly (GO:0006333)3.18927367
68IMP metabolic process (GO:0046040)3.18431376
69regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.17170436
70regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.17055583
71negative regulation of DNA recombination (GO:0045910)3.14891681
72folic acid-containing compound biosynthetic process (GO:0009396)3.14073789
73telomere maintenance via recombination (GO:0000722)3.13431821
74spindle assembly checkpoint (GO:0071173)3.12974071
75protein K6-linked ubiquitination (GO:0085020)3.12705608
76* histone exchange (GO:0043486)3.12395027
77pre-miRNA processing (GO:0031054)3.12059429
78formation of translation preinitiation complex (GO:0001731)3.10032342
79telomere maintenance via semi-conservative replication (GO:0032201)3.09838903
80negative regulation of DNA-dependent DNA replication (GO:2000104)3.09817645
81histone H2A monoubiquitination (GO:0035518)3.09763885
82* chromatin assembly (GO:0031497)3.08916301
83regulation of mitotic sister chromatid separation (GO:0010965)3.08358696
84regulation of mitotic sister chromatid segregation (GO:0033047)3.08358696
85regulation of sister chromatid segregation (GO:0033045)3.08358696
86negative regulation of chromosome segregation (GO:0051985)3.07229778
87DNA conformation change (GO:0071103)3.07199520
88negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.04657825
89negative regulation of sister chromatid segregation (GO:0033046)3.04117907
90negative regulation of mitotic sister chromatid separation (GO:2000816)3.04117907
91negative regulation of mitotic sister chromatid segregation (GO:0033048)3.04117907
92negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.04117907
93monoubiquitinated protein deubiquitination (GO:0035520)3.03997171
94regulation of nucleobase-containing compound transport (GO:0032239)3.03865977
95mitotic spindle assembly checkpoint (GO:0007094)3.02896913
96nuclear envelope organization (GO:0006998)3.02671797
97* ATP-dependent chromatin remodeling (GO:0043044)3.01282610
98purine nucleobase biosynthetic process (GO:0009113)2.98418505
99protein complex localization (GO:0031503)2.97669919
100protein-DNA complex disassembly (GO:0032986)2.97660844
101nucleosome disassembly (GO:0006337)2.97660844
102negative regulation of DNA repair (GO:0045738)2.96173280
103chromosome segregation (GO:0007059)2.96047637
104sister chromatid cohesion (GO:0007062)2.94456659
105negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.94385550
106somatic hypermutation of immunoglobulin genes (GO:0016446)2.91224879
107somatic diversification of immune receptors via somatic mutation (GO:0002566)2.91224879
108DNA damage response, detection of DNA damage (GO:0042769)2.91194590
109mRNA transport (GO:0051028)2.90426088
110regulation of centrosome duplication (GO:0010824)2.89996430
111DNA double-strand break processing (GO:0000729)2.89813213
112translesion synthesis (GO:0019985)2.89669280
113regulation of gene silencing by miRNA (GO:0060964)2.89157721
114regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.87537353
115regulation of mitotic spindle checkpoint (GO:1903504)2.87537353
116negative regulation of fibroblast apoptotic process (GO:2000270)2.85620318
117negative regulation of RNA splicing (GO:0033119)2.85364980
118mitotic spindle organization (GO:0007052)2.81927986
119V(D)J recombination (GO:0033151)2.80609816
120RNA-dependent DNA replication (GO:0006278)2.77352644
121mitotic G2/M transition checkpoint (GO:0044818)2.76201419
122termination of RNA polymerase II transcription (GO:0006369)2.76096883
123negative regulation of mRNA processing (GO:0050686)2.74290485
124positive regulation of cell cycle checkpoint (GO:1901978)2.72503277

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.33571884
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.51232779
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.62054800
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.49946429
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.39731138
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.02406959
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.64865064
8AR_21909140_ChIP-Seq_LNCAP_Human2.63031969
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.61262430
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.53340770
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.50388702
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.44375228
13* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33634273
14MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.27640525
15* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.26210318
16MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.10314776
17E2F7_22180533_ChIP-Seq_HELA_Human10.7860926
18TP63_19390658_ChIP-ChIP_HaCaT_Human1.93153626
19RBPJ_22232070_ChIP-Seq_NCS_Mouse1.92643384
20MYCN_18555785_ChIP-Seq_MESCs_Mouse1.91233012
21ELK1_19687146_ChIP-ChIP_HELA_Human1.90946603
22EWS_26573619_Chip-Seq_HEK293_Human1.89492984
23PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84835348
24* EST1_17652178_ChIP-ChIP_JURKAT_Human1.84793171
25* XRN2_22483619_ChIP-Seq_HELA_Human1.84718941
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.84276030
27* VDR_23849224_ChIP-Seq_CD4+_Human1.83655118
28MYC_18358816_ChIP-ChIP_MESCs_Mouse1.83285033
29* CREB1_15753290_ChIP-ChIP_HEK293T_Human1.82421819
30IGF1R_20145208_ChIP-Seq_DFB_Human1.80969204
31FUS_26573619_Chip-Seq_HEK293_Human1.79908619
32KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.79884045
33GABP_17652178_ChIP-ChIP_JURKAT_Human1.69560982
34MYC_22102868_ChIP-Seq_BL_Human1.69092358
35YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.67088322
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64644563
37ETS1_20019798_ChIP-Seq_JURKAT_Human1.63274954
38SOX2_16153702_ChIP-ChIP_HESCs_Human1.62816703
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.62273670
40WT1_19549856_ChIP-ChIP_CCG9911_Human1.59964603
41HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.55354149
42SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.55237995
43FOXP3_21729870_ChIP-Seq_TREG_Human1.54272717
44ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.51922226
45TAF15_26573619_Chip-Seq_HEK293_Human1.48455083
46ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.48029451
47TTF2_22483619_ChIP-Seq_HELA_Human1.47996486
48NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.45985140
49KDM5A_27292631_Chip-Seq_BREAST_Human1.45568343
50NANOG_18555785_ChIP-Seq_MESCs_Mouse1.40987520
51KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.40330982
52KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.40330982
53KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.40330982
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39918661
55PADI4_21655091_ChIP-ChIP_MCF-7_Human1.39722940
56DCP1A_22483619_ChIP-Seq_HELA_Human1.39457772
57CIITA_25753668_ChIP-Seq_RAJI_Human1.39269801
58E2F1_18555785_ChIP-Seq_MESCs_Mouse1.37005022
59HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.36727061
60SOX2_18555785_ChIP-Seq_MESCs_Mouse1.36090551
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34093409
62* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33529049
63E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.31811014
64TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.28235146
65GABP_19822575_ChIP-Seq_HepG2_Human1.24209940
66JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.23170885
67TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.22889141
68SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.22713488
69* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.20793975
70ELF1_17652178_ChIP-ChIP_JURKAT_Human1.19304880
71HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.18314723
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.17589485
73SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.16858321
74CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.16658023
75SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.14559403
76MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.14481328
77KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13489087
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.13305499
79IRF1_19129219_ChIP-ChIP_H3396_Human1.13157329
80* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.11203203
81E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09726662
82POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08436454
83PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.08297849
84SOX17_20123909_ChIP-Seq_XEN_Mouse1.06995149
85TFEB_21752829_ChIP-Seq_HELA_Human1.06360354
86* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06171775
87ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.05474447
88POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.03976174
89ZNF274_21170338_ChIP-Seq_K562_Hela1.03382094
90SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03304400
91GATA1_26923725_Chip-Seq_HPCs_Mouse1.00214331
92FLI1_27457419_Chip-Seq_LIVER_Mouse0.99163973
93KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97347417
94CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.96889465
95ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.95747524
96THAP11_20581084_ChIP-Seq_MESCs_Mouse0.95670545
97CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95554609
98TCF3_18692474_ChIP-Seq_MEFs_Mouse0.95360809
99ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94958127
100ERG_20887958_ChIP-Seq_HPC-7_Mouse0.94762116
101TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.94255293
102CHD1_26751641_Chip-Seq_LNCaP_Human0.94128560
103NANOG_21062744_ChIP-ChIP_HESCs_Human0.93797806
104SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.92506126
105FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.92155404
106P300_19829295_ChIP-Seq_ESCs_Human0.90706283
107DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.89824952
108PKCTHETA_26484144_Chip-Seq_BREAST_Human0.89725557
109TCF3_18692474_ChIP-Seq_MESCs_Mouse0.88764332
110HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.87980602
111MYC_18940864_ChIP-ChIP_HL60_Human0.87827823
112SOX9_26525672_Chip-Seq_HEART_Mouse0.87672215
113REST_19997604_ChIP-ChIP_NEURONS_Mouse0.87584693
114MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.87091659
115FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.86388662
116ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.86351736
117CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.84743586
118SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.84255557
119TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83596919
120OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.83574360
121CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.80920790
122NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.80104126
123POU5F1_16153702_ChIP-ChIP_HESCs_Human0.79825979
124MYB_26560356_Chip-Seq_TH1_Human0.79256111
125NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.79119455
126NANOG_16153702_ChIP-ChIP_HESCs_Human0.77126052
127NOTCH1_21737748_ChIP-Seq_TLL_Human0.76720798

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.29007947
2MP0010094_abnormal_chromosome_stability4.15315461
3MP0003693_abnormal_embryo_hatching4.04468179
4MP0003111_abnormal_nucleus_morphology3.66186772
5* MP0004957_abnormal_blastocyst_morpholog3.46184786
6MP0003077_abnormal_cell_cycle3.45204850
7MP0010352_gastrointestinal_tract_polyps2.84880407
8MP0008058_abnormal_DNA_repair2.75635992
9MP0008007_abnormal_cellular_replicative2.75571788
10MP0008877_abnormal_DNA_methylation2.64505746
11MP0003123_paternal_imprinting2.61987564
12MP0010307_abnormal_tumor_latency2.49339606
13* MP0001730_embryonic_growth_arrest2.19359463
14MP0000350_abnormal_cell_proliferation2.16999066
15MP0005076_abnormal_cell_differentiation1.96839701
16MP0002396_abnormal_hematopoietic_system1.94213897
17* MP0008932_abnormal_embryonic_tissue1.94078214
18MP0003121_genomic_imprinting1.91802240
19MP0003786_premature_aging1.79951877
20MP0002084_abnormal_developmental_patter1.76874078
21MP0003221_abnormal_cardiomyocyte_apopto1.75621157
22MP0004197_abnormal_fetal_growth/weight/1.74946060
23* MP0005380_embryogenesis_phenotype1.74857953
24* MP0001672_abnormal_embryogenesis/_devel1.74857953
25MP0004808_abnormal_hematopoietic_stem1.70185989
26MP0001697_abnormal_embryo_size1.68417381
27MP0005394_taste/olfaction_phenotype1.67126706
28MP0005499_abnormal_olfactory_system1.67126706
29MP0001188_hyperpigmentation1.63622524
30MP0003984_embryonic_growth_retardation1.60630253
31MP0000490_abnormal_crypts_of1.60292894
32* MP0002085_abnormal_embryonic_tissue1.59628075
33MP0003890_abnormal_embryonic-extraembry1.58212081
34MP0002088_abnormal_embryonic_growth/wei1.57940108
35MP0002233_abnormal_nose_morphology1.57768635
36MP0008789_abnormal_olfactory_epithelium1.57141502
37* MP0002086_abnormal_extraembryonic_tissu1.55394977
38MP0005187_abnormal_penis_morphology1.49884085
39MP0009697_abnormal_copulation1.49795348
40MP0000537_abnormal_urethra_morphology1.49568050
41MP0003567_abnormal_fetal_cardiomyocyte1.49401231
42MP0003385_abnormal_body_wall1.48754346
43MP0001529_abnormal_vocalization1.48451923
44MP0001293_anophthalmia1.44893879
45MP0000778_abnormal_nervous_system1.43053517
46MP0001299_abnormal_eye_distance/1.43029588
47* MP0002080_prenatal_lethality1.41580213
48MP0002009_preneoplasia1.34695475
49MP0002877_abnormal_melanocyte_morpholog1.34645878
50MP0003122_maternal_imprinting1.34211291
51MP0003861_abnormal_nervous_system1.33785400
52MP0003705_abnormal_hypodermis_morpholog1.32976654
53MP0006072_abnormal_retinal_apoptosis1.30111565
54MP0003937_abnormal_limbs/digits/tail_de1.27467597
55MP0003787_abnormal_imprinting1.25824832
56MP0002210_abnormal_sex_determination1.25197415
57MP0009053_abnormal_anal_canal1.22088509
58MP0010234_abnormal_vibrissa_follicle1.21897854
59MP0000049_abnormal_middle_ear1.18974269
60MP0005248_abnormal_Harderian_gland1.18387948
61* MP0000313_abnormal_cell_death1.16394917
62MP0002019_abnormal_tumor_incidence1.15919590
63MP0010030_abnormal_orbit_morphology1.14307039
64MP0000569_abnormal_digit_pigmentation1.13183539
65MP0000647_abnormal_sebaceous_gland1.10747351
66MP0002751_abnormal_autonomic_nervous1.10446021
67MP0003941_abnormal_skin_development1.09392637
68MP0001145_abnormal_male_reproductive1.09156417
69MP0002006_tumorigenesis1.05734114
70MP0009703_decreased_birth_body1.04355668
71MP0000428_abnormal_craniofacial_morphol1.01767471
72MP0005391_vision/eye_phenotype0.99995588
73MP0000733_abnormal_muscle_development0.99553149
74MP0000703_abnormal_thymus_morphology0.99214207
75MP0003763_abnormal_thymus_physiology0.99135497
76MP0001177_atelectasis0.98796426
77MP0000631_abnormal_neuroendocrine_gland0.97082534
78MP0002092_abnormal_eye_morphology0.96853882
79MP0000566_synostosis0.96839321
80MP0002166_altered_tumor_susceptibility0.95308337
81MP0001929_abnormal_gametogenesis0.94580683
82MP0006054_spinal_hemorrhage0.94261422
83MP0001545_abnormal_hematopoietic_system0.94239804
84MP0005397_hematopoietic_system_phenotyp0.94239804
85MP0000653_abnormal_sex_gland0.93456674
86MP0002081_perinatal_lethality0.93274578
87MP0003315_abnormal_perineum_morphology0.91965011
88MP0001915_intracranial_hemorrhage0.91465787
89MP0009672_abnormal_birth_weight0.91150462
90MP0003718_maternal_effect0.91079680
91MP0001286_abnormal_eye_development0.90944640
92MP0003566_abnormal_cell_adhesion0.90609680
93MP0000432_abnormal_head_morphology0.89614282
94MP0002697_abnormal_eye_size0.87307763
95MP0005623_abnormal_meninges_morphology0.86941296
96MP0001849_ear_inflammation0.85908867
97MP0002111_abnormal_tail_morphology0.84725850
98MP0004133_heterotaxia0.82125964
99MP0002398_abnormal_bone_marrow0.80964393
100MP0003119_abnormal_digestive_system0.80937144
101MP0002160_abnormal_reproductive_system0.79225052
102MP0001119_abnormal_female_reproductive0.78524268
103MP0002102_abnormal_ear_morphology0.78049012
104MP0003935_abnormal_craniofacial_develop0.77735456
105MP0010678_abnormal_skin_adnexa0.76793247
106MP0005389_reproductive_system_phenotype0.75998347
107MP0002152_abnormal_brain_morphology0.75511329
108MP0004811_abnormal_neuron_physiology0.75431430
109MP0003942_abnormal_urinary_system0.74708950
110MP0003136_yellow_coat_color0.74566098
111MP0009278_abnormal_bone_marrow0.74489013
112MP0008995_early_reproductive_senescence0.74416795
113MP0000516_abnormal_urinary_system0.73965086
114MP0005367_renal/urinary_system_phenotyp0.73965086
115MP0002254_reproductive_system_inflammat0.73203495
116MP0005621_abnormal_cell_physiology0.72775730
117MP0002925_abnormal_cardiovascular_devel0.72751988
118MP0000955_abnormal_spinal_cord0.72624457
119MP0003755_abnormal_palate_morphology0.70804884
120MP0003115_abnormal_respiratory_system0.70364021
121MP0002722_abnormal_immune_system0.69690950
122MP0000383_abnormal_hair_follicle0.69528469
123MP0009333_abnormal_splenocyte_physiolog0.68783572
124MP0003448_altered_tumor_morphology0.68363650
125MP0005023_abnormal_wound_healing0.68214159
126MP0005384_cellular_phenotype0.66998328
127MP0001340_abnormal_eyelid_morphology0.66255201
128MP0000477_abnormal_intestine_morphology0.65917927
129MP0002177_abnormal_outer_ear0.65622946
130MP0002234_abnormal_pharynx_morphology0.64486545
131MP0002114_abnormal_axial_skeleton0.64113141
132MP0006292_abnormal_olfactory_placode0.63374704
133MP0002938_white_spotting0.62372596
134MP0000858_altered_metastatic_potential0.60880592
135MP0000689_abnormal_spleen_morphology0.60761861
136MP0003936_abnormal_reproductive_system0.60578604

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.30552925
2Cortical dysplasia (HP:0002539)4.02502285
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.84542307
4Volvulus (HP:0002580)3.71042711
5Abnormality of chromosome stability (HP:0003220)3.58181506
6Hepatoblastoma (HP:0002884)3.57247778
7Birth length less than 3rd percentile (HP:0003561)3.51583613
8Colon cancer (HP:0003003)3.13821128
9Medulloblastoma (HP:0002885)3.12733809
10Selective tooth agenesis (HP:0001592)3.11667561
11Ependymoma (HP:0002888)3.02148937
12Meckel diverticulum (HP:0002245)2.95187259
13Abnormality of the labia minora (HP:0012880)2.86388195
14Ectopic kidney (HP:0000086)2.84249784
15Aplasia/Hypoplasia of the uvula (HP:0010293)2.82796160
16Deviation of the thumb (HP:0009603)2.81975581
17Abnormality of the preputium (HP:0100587)2.80694033
18Proximal placement of thumb (HP:0009623)2.78374563
19Abnormality of the ileum (HP:0001549)2.74591574
2011 pairs of ribs (HP:0000878)2.71607603
21Rhabdomyosarcoma (HP:0002859)2.71346886
22Impulsivity (HP:0100710)2.65896149
23Increased nuchal translucency (HP:0010880)2.64477271
24Patellar aplasia (HP:0006443)2.61649860
25Myelodysplasia (HP:0002863)2.59299374
26Biliary tract neoplasm (HP:0100574)2.55488970
27Small intestinal stenosis (HP:0012848)2.53327794
28Duodenal stenosis (HP:0100867)2.53327794
29Missing ribs (HP:0000921)2.50785210
30Intestinal atresia (HP:0011100)2.46512909
31Breast hypoplasia (HP:0003187)2.43354624
32Aplasia/Hypoplasia of the patella (HP:0006498)2.42955790
33Agnosia (HP:0010524)2.40998420
34Abnormality of the astrocytes (HP:0100707)2.38004835
35Astrocytoma (HP:0009592)2.38004835
36Reticulocytopenia (HP:0001896)2.36947656
37Thyroid carcinoma (HP:0002890)2.36385879
38Neoplasm of the oral cavity (HP:0100649)2.30963704
39Shoulder girdle muscle weakness (HP:0003547)2.29116749
40Basal cell carcinoma (HP:0002671)2.26181714
41Absent radius (HP:0003974)2.22622631
42Amaurosis fugax (HP:0100576)2.21826757
43Transitional cell carcinoma of the bladder (HP:0006740)2.20771632
44Glioma (HP:0009733)2.18562953
45High anterior hairline (HP:0009890)2.18265558
46Abnormality of the carotid arteries (HP:0005344)2.17189164
47Prominent nose (HP:0000448)2.16363784
48Embryonal neoplasm (HP:0002898)2.14997112
49Facial hemangioma (HP:0000329)2.14438768
50Uterine leiomyosarcoma (HP:0002891)2.13422685
51Leiomyosarcoma (HP:0100243)2.13422685
52Insidious onset (HP:0003587)2.13234743
53Termporal pattern (HP:0011008)2.13234743
54Sloping forehead (HP:0000340)2.13036575
55Cutaneous melanoma (HP:0012056)2.12526435
56Nephroblastoma (Wilms tumor) (HP:0002667)2.10590198
57Supernumerary spleens (HP:0009799)2.10541395
58Gastrointestinal carcinoma (HP:0002672)2.10377904
59Malignant gastrointestinal tract tumors (HP:0006749)2.10377904
60Abnormality of the duodenum (HP:0002246)2.08833504
61Atresia of the external auditory canal (HP:0000413)2.08221556
62Short 4th metacarpal (HP:0010044)2.07270341
63Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.07270341
64Acute myeloid leukemia (HP:0004808)2.06678121
65Neoplasm of the pancreas (HP:0002894)2.06081530
66Absent forearm bone (HP:0003953)2.05612018
67Aplasia involving forearm bones (HP:0009822)2.05612018
68Cafe-au-lait spot (HP:0000957)2.05532430
69Abnormality of the anterior horn cell (HP:0006802)2.04793118
70Degeneration of anterior horn cells (HP:0002398)2.04793118
71Absent thumb (HP:0009777)2.02768593
72Abnormality of the fingertips (HP:0001211)2.02438199
73Spastic diplegia (HP:0001264)2.01884890
74Long eyelashes (HP:0000527)2.01262189
75Bladder carcinoma (HP:0002862)2.00682094
76Bladder neoplasm (HP:0009725)2.00682094
77Embryonal renal neoplasm (HP:0011794)2.00600689
78Abnormal lung lobation (HP:0002101)1.99952463
79Septo-optic dysplasia (HP:0100842)1.99704549
80Abnormal number of incisors (HP:0011064)1.98171183
81Abnormality of the musculature of the pelvis (HP:0001469)1.97931789
82Abnormality of the hip-girdle musculature (HP:0001445)1.97931789
83Pelvic girdle muscle weakness (HP:0003749)1.96995228
84Aplasia/Hypoplasia of the sternum (HP:0006714)1.94232257
85Neoplasm of the small intestine (HP:0100833)1.93578722
86Neoplasm of striated muscle (HP:0009728)1.92958069
87Sandal gap (HP:0001852)1.92457564
88Squamous cell carcinoma (HP:0002860)1.90714610
89Abnormality of chromosome segregation (HP:0002916)1.88652960
90Neoplasm of the adrenal cortex (HP:0100641)1.85691878
91Deep philtrum (HP:0002002)1.85158180
92Abnormal hair whorl (HP:0010721)1.84623292
93Clubbing of toes (HP:0100760)1.84087421
94Ovarian neoplasm (HP:0100615)1.82480288
95Bone marrow hypocellularity (HP:0005528)1.81453898
96Supernumerary ribs (HP:0005815)1.80173551
97Tracheoesophageal fistula (HP:0002575)1.77282103
98Breast carcinoma (HP:0003002)1.75200158
99Duplicated collecting system (HP:0000081)1.75171005
100Supernumerary bones of the axial skeleton (HP:0009144)1.74524307
101Abnormality of the septum pellucidum (HP:0007375)1.74010889
102Blepharitis (HP:0000498)1.73924897
103Abnormality of the antihelix (HP:0009738)1.73857301
104Carpal bone hypoplasia (HP:0001498)1.73122926
105Short thumb (HP:0009778)1.73055971
106Abnormal biliary tract morphology (HP:0012440)1.72928158
107Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.72387626
108Trigonocephaly (HP:0000243)1.71414499
109High pitched voice (HP:0001620)1.71288694
110Horseshoe kidney (HP:0000085)1.70907723
111Neoplasm of the colon (HP:0100273)1.70652849
112Overlapping toe (HP:0001845)1.70443618
113Generalized hypotonia (HP:0001290)1.70384958
114Papillary thyroid carcinoma (HP:0002895)1.69541375
115Impaired vibration sensation in the lower limbs (HP:0002166)1.69362691
116Cutaneous syndactyly (HP:0012725)1.69159508
117Multiple enchondromatosis (HP:0005701)1.69114381
118Abnormality of the calcaneus (HP:0008364)1.68848069
119Cutis marmorata (HP:0000965)1.68486013
120Uterine neoplasm (HP:0010784)1.68455006
121Arteriovenous malformation (HP:0100026)1.67769098
122Duplication of thumb phalanx (HP:0009942)1.67731208
123Triphalangeal thumb (HP:0001199)1.67627384
124Partial agenesis of the corpus callosum (HP:0001338)1.67201574
125Truncal obesity (HP:0001956)1.67082823
126Oral leukoplakia (HP:0002745)1.66902764
127Micropenis (HP:0000054)1.66827701
128Subacute progressive viral hepatitis (HP:0006572)1.66681428
129Gastrointestinal atresia (HP:0002589)1.66490812
130Stenosis of the external auditory canal (HP:0000402)1.66015159
131Cystic hygroma (HP:0000476)1.65970910
132Bifid tongue (HP:0010297)1.65305029
133Absent eyebrow (HP:0002223)1.64973444
134Skull defect (HP:0001362)1.64860655
135Genital tract atresia (HP:0001827)1.64620052
136Spinal cord lesions (HP:0100561)1.64131438
137Syringomyelia (HP:0003396)1.64131438
138Low anterior hairline (HP:0000294)1.63721398
139Vaginal atresia (HP:0000148)1.63326404
140Cutaneous finger syndactyly (HP:0010554)1.63244098
141Abnormality of DNA repair (HP:0003254)1.62664158
142Drooling (HP:0002307)1.62522297
143Obsessive-compulsive behavior (HP:0000722)1.61959949
144Broad foot (HP:0001769)1.59054398
145Facial cleft (HP:0002006)1.56236784
146Hyperglycinemia (HP:0002154)1.56137159
147Omphalocele (HP:0001539)1.55441025
148Esophageal atresia (HP:0002032)1.52914831
149Renal hypoplasia (HP:0000089)1.50632208

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.70549630
2CDK123.72106291
3WEE13.60406951
4NEK22.86787614
5SRPK12.75796199
6MKNK12.73998700
7TRIM282.54886746
8BUB12.51599837
9TTK2.34644805
10MKNK22.29106089
11MAP3K42.20650385
12BRSK22.12517376
13TSSK62.03981899
14ACVR1B1.95253151
15EIF2AK11.95155452
16PLK11.88117091
17ATR1.84395086
18RPS6KB21.83725379
19PLK31.81316631
20AURKB1.75742888
21PASK1.73768430
22CDK71.68234965
23LATS11.66909340
24EEF2K1.66580050
25BRD41.64069013
26PLK41.62505651
27TAF11.59470625
28TNIK1.56148743
29CHEK11.54670461
30CDK41.54592084
31RPS6KA41.54550423
32EPHA21.51707904
33DYRK31.49583495
34STK101.49471152
35STK31.47599927
36NEK11.45823093
37CHEK21.45251360
38MAP2K71.41255348
39CDK61.39962097
40STK41.38796916
41ZAK1.36909132
42ALK1.36854401
43TLK11.35270852
44ATM1.32012394
45PNCK1.29887968
46MAP3K81.25790022
47SCYL21.20700767
48CASK1.16638442
49MAP3K101.15767508
50CSNK1G21.15474263
51MELK1.14670885
52PKN21.14534321
53EIF2AK31.11763782
54WNK31.07521232
55VRK11.06209991
56PIM11.03801113
57CSNK1G31.02244258
58* CDK21.01998520
59TGFBR11.00395514
60LATS20.97193342
61YES10.92848701
62PLK20.91916191
63BRSK10.89231490
64CDK90.88340107
65STK240.85238250
66NUAK10.84933381
67CDK10.81900008
68RPS6KA50.79314536
69ERBB30.79262683
70PAK40.77541946
71DYRK20.76894108
72KSR10.74543189
73UHMK10.74085443
74MTOR0.73714839
75AURKA0.73390883
76CDK190.70676558
77CSNK1D0.67520037
78CHUK0.67467488
79FRK0.66190976
80DYRK1B0.66178455
81CSNK2A20.65929535
82CDK30.65452012
83MST40.63030413
84CAMK1G0.61021385
85CDK180.59063800
86MARK30.59000360
87FGFR10.57745678
88PRKDC0.57259367
89STK38L0.56587440
90CDK140.56327043
91CSNK1E0.54791905
92PBK0.54371456
93NME20.52622542
94FGFR30.51517005
95EIF2AK20.51230934
96PTK60.50342979
97CDK150.50123767
98SIK30.50119954
99EPHA30.48665160
100CDK11A0.48269063
101CSNK2A10.48069040
102LRRK20.47715108
103CLK10.47511949
104ERBB40.47498985
105MINK10.47317232
106TIE10.46124348
107PAK20.45585117
108* MAPK140.45274842
109TRPM70.44540150
110DYRK1A0.44202658
111JAK30.43933010
112BRAF0.41618327
113RPS6KB10.41605809
114NEK90.41530248
115FLT30.40784722
116CSNK1A1L0.40528108
117AKT30.38996157
118MAP4K10.38865465
119MAPK100.38308568
120TTN0.36654287
121CAMK1D0.36583045
122TESK20.36373425
123EGFR0.36364339
124CDK80.35953334
125PDGFRA0.35231469
126AKT10.33962872
127ICK0.33669609
128MAPK10.32633514
129GSK3B0.31079270
130CSNK1G10.29837301
131BMX0.29741233
132MET0.29371796
133TEC0.28656350
134BCR0.27424037
135FGFR20.26771178
136PDGFRB0.26174858

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.90160643
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.62472720
3Mismatch repair_Homo sapiens_hsa034303.58886397
4RNA transport_Homo sapiens_hsa030133.28937197
5Cell cycle_Homo sapiens_hsa041103.13573918
6Spliceosome_Homo sapiens_hsa030403.11437309
7Homologous recombination_Homo sapiens_hsa034402.61816120
8Non-homologous end-joining_Homo sapiens_hsa034502.59981428
9Nucleotide excision repair_Homo sapiens_hsa034202.48734629
10Fanconi anemia pathway_Homo sapiens_hsa034602.44861985
11Base excision repair_Homo sapiens_hsa034102.38700527
12One carbon pool by folate_Homo sapiens_hsa006702.38047055
13mRNA surveillance pathway_Homo sapiens_hsa030152.35344878
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.35258547
15RNA polymerase_Homo sapiens_hsa030202.27511757
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.08040888
17RNA degradation_Homo sapiens_hsa030182.07866998
18Basal transcription factors_Homo sapiens_hsa030222.03584520
19Steroid biosynthesis_Homo sapiens_hsa001001.99787159
20Systemic lupus erythematosus_Homo sapiens_hsa053221.87411279
21p53 signaling pathway_Homo sapiens_hsa041151.83765044
22Protein export_Homo sapiens_hsa030601.80379215
23Viral carcinogenesis_Homo sapiens_hsa052031.54245434
24Ribosome_Homo sapiens_hsa030101.52778585
25Pyrimidine metabolism_Homo sapiens_hsa002401.51603394
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.49349256
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.36857063
28MicroRNAs in cancer_Homo sapiens_hsa052061.35322056
29Antigen processing and presentation_Homo sapiens_hsa046121.31906002
30Epstein-Barr virus infection_Homo sapiens_hsa051691.28236106
31Herpes simplex infection_Homo sapiens_hsa051681.27953318
32Proteasome_Homo sapiens_hsa030501.25897236
33Propanoate metabolism_Homo sapiens_hsa006401.23596730
34Small cell lung cancer_Homo sapiens_hsa052221.15888468
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.15855388
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.13969199
37HTLV-I infection_Homo sapiens_hsa051661.12394648
38Oocyte meiosis_Homo sapiens_hsa041141.10981531
39TGF-beta signaling pathway_Homo sapiens_hsa043501.08041987
40Transcriptional misregulation in cancer_Homo sapiens_hsa052021.05726948
41Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99305627
42Biosynthesis of amino acids_Homo sapiens_hsa012300.98085934
43Chronic myeloid leukemia_Homo sapiens_hsa052200.91622350
44Thyroid cancer_Homo sapiens_hsa052160.90650655
45Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.89654636
46Adherens junction_Homo sapiens_hsa045200.87438692
47Selenocompound metabolism_Homo sapiens_hsa004500.87002903
48Colorectal cancer_Homo sapiens_hsa052100.85997716
49Alcoholism_Homo sapiens_hsa050340.84891281
50Hippo signaling pathway_Homo sapiens_hsa043900.82523092
51NF-kappa B signaling pathway_Homo sapiens_hsa040640.82395197
52Prostate cancer_Homo sapiens_hsa052150.80958164
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79810420
54Pyruvate metabolism_Homo sapiens_hsa006200.79214639
55Purine metabolism_Homo sapiens_hsa002300.78343078
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.77949930
57Hepatitis B_Homo sapiens_hsa051610.75616432
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.74569104
59Viral myocarditis_Homo sapiens_hsa054160.73379338
60NOD-like receptor signaling pathway_Homo sapiens_hsa046210.72258835
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71563816
62Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.71207926
63Legionellosis_Homo sapiens_hsa051340.70953002
64Measles_Homo sapiens_hsa051620.70471203
65Basal cell carcinoma_Homo sapiens_hsa052170.69641727
66Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.68932523
67Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66179226
68Notch signaling pathway_Homo sapiens_hsa043300.66112273
69mTOR signaling pathway_Homo sapiens_hsa041500.66000332
70Carbon metabolism_Homo sapiens_hsa012000.65746117
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.65154134
72Axon guidance_Homo sapiens_hsa043600.63507622
73Apoptosis_Homo sapiens_hsa042100.63217253
74Pancreatic cancer_Homo sapiens_hsa052120.61850083
75Pathways in cancer_Homo sapiens_hsa052000.60089504
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59952469
77Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58733143
78Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.57855655
79Primary immunodeficiency_Homo sapiens_hsa053400.57426372
80Proteoglycans in cancer_Homo sapiens_hsa052050.55803744
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.54482010
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.54248948
83Influenza A_Homo sapiens_hsa051640.52840575
84Non-small cell lung cancer_Homo sapiens_hsa052230.50095970
85FoxO signaling pathway_Homo sapiens_hsa040680.49778637
86Tight junction_Homo sapiens_hsa045300.48985825
87Lysine degradation_Homo sapiens_hsa003100.48706222
88Leukocyte transendothelial migration_Homo sapiens_hsa046700.47307509
89Endometrial cancer_Homo sapiens_hsa052130.46620821
90Shigellosis_Homo sapiens_hsa051310.45895836
91Folate biosynthesis_Homo sapiens_hsa007900.45008365
92Wnt signaling pathway_Homo sapiens_hsa043100.44725956
93Acute myeloid leukemia_Homo sapiens_hsa052210.44527279
94T cell receptor signaling pathway_Homo sapiens_hsa046600.44014644
95Toxoplasmosis_Homo sapiens_hsa051450.42965093
96Hematopoietic cell lineage_Homo sapiens_hsa046400.42733809
97Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.42094131
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41618310
99Jak-STAT signaling pathway_Homo sapiens_hsa046300.41187219
100Bladder cancer_Homo sapiens_hsa052190.39143896
101Circadian rhythm_Homo sapiens_hsa047100.39108386
102Hedgehog signaling pathway_Homo sapiens_hsa043400.38589659
103Melanoma_Homo sapiens_hsa052180.38588097
104B cell receptor signaling pathway_Homo sapiens_hsa046620.38469972
105PI3K-Akt signaling pathway_Homo sapiens_hsa041510.38282104
106Focal adhesion_Homo sapiens_hsa045100.37713136
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.37534738
108Gap junction_Homo sapiens_hsa045400.37466015
109Melanogenesis_Homo sapiens_hsa049160.37382465
110HIF-1 signaling pathway_Homo sapiens_hsa040660.35922711
111AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35771391
112ECM-receptor interaction_Homo sapiens_hsa045120.35311794
113Leishmaniasis_Homo sapiens_hsa051400.34858801
114Intestinal immune network for IgA production_Homo sapiens_hsa046720.33370209
115Renal cell carcinoma_Homo sapiens_hsa052110.33083128
116Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32760692
117Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32672825
118TNF signaling pathway_Homo sapiens_hsa046680.32186244
119Fatty acid elongation_Homo sapiens_hsa000620.30949643
120ErbB signaling pathway_Homo sapiens_hsa040120.30814457
121Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.29574992
122Dorso-ventral axis formation_Homo sapiens_hsa043200.29179575
123Regulation of actin cytoskeleton_Homo sapiens_hsa048100.29050428
124Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28676534
125Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.28325911
126Graft-versus-host disease_Homo sapiens_hsa053320.27479733
127Allograft rejection_Homo sapiens_hsa053300.25905448
128Pentose phosphate pathway_Homo sapiens_hsa000300.25677990
129Vitamin B6 metabolism_Homo sapiens_hsa007500.24856551
130RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.24339704
131Fatty acid metabolism_Homo sapiens_hsa012120.23513211
132AMPK signaling pathway_Homo sapiens_hsa041520.19955409
133Glioma_Homo sapiens_hsa052140.19341593
134Inositol phosphate metabolism_Homo sapiens_hsa005620.19102176
135Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.18847008

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