Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 6.10097966 |
2 | nuclear pore organization (GO:0006999) | 5.94711449 |
3 | protein localization to kinetochore (GO:0034501) | 5.03753959 |
4 | establishment of integrated proviral latency (GO:0075713) | 4.89761344 |
5 | pore complex assembly (GO:0046931) | 4.66399170 |
6 | DNA unwinding involved in DNA replication (GO:0006268) | 4.47799245 |
7 | mitotic sister chromatid cohesion (GO:0007064) | 4.45664079 |
8 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.33372810 |
9 | mitotic chromosome condensation (GO:0007076) | 4.26196611 |
10 | mitotic metaphase plate congression (GO:0007080) | 4.23675638 |
11 | protein localization to chromosome, centromeric region (GO:0071459) | 4.21031884 |
12 | kinetochore organization (GO:0051383) | 4.09092109 |
13 | mitotic nuclear envelope disassembly (GO:0007077) | 4.07840188 |
14 | regulation of RNA export from nucleus (GO:0046831) | 3.93459776 |
15 | DNA replication initiation (GO:0006270) | 3.92003704 |
16 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.90710676 |
17 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.90710676 |
18 | non-recombinational repair (GO:0000726) | 3.89866853 |
19 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.89866853 |
20 | paraxial mesoderm development (GO:0048339) | 3.87756768 |
21 | metaphase plate congression (GO:0051310) | 3.85047963 |
22 | membrane disassembly (GO:0030397) | 3.84940555 |
23 | nuclear envelope disassembly (GO:0051081) | 3.84940555 |
24 | positive regulation of chromosome segregation (GO:0051984) | 3.82937306 |
25 | DNA ligation (GO:0006266) | 3.77851178 |
26 | regulation of histone H3-K9 methylation (GO:0051570) | 3.77165874 |
27 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.76133245 |
28 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.76133245 |
29 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.76133245 |
30 | sister chromatid segregation (GO:0000819) | 3.74288080 |
31 | regulation of spindle organization (GO:0090224) | 3.71688359 |
32 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.60971246 |
33 | establishment of viral latency (GO:0019043) | 3.60871059 |
34 | DNA replication checkpoint (GO:0000076) | 3.60601944 |
35 | regulation of helicase activity (GO:0051095) | 3.59054634 |
36 | DNA duplex unwinding (GO:0032508) | 3.59006360 |
37 | DNA geometric change (GO:0032392) | 3.57628466 |
38 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.55993866 |
39 | * chromatin remodeling at centromere (GO:0031055) | 3.55904537 |
40 | mitotic sister chromatid segregation (GO:0000070) | 3.55487852 |
41 | regulation of sister chromatid cohesion (GO:0007063) | 3.52811591 |
42 | meiotic chromosome segregation (GO:0045132) | 3.50798963 |
43 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.49889277 |
44 | dosage compensation (GO:0007549) | 3.43497824 |
45 | IMP biosynthetic process (GO:0006188) | 3.43148588 |
46 | ribosome assembly (GO:0042255) | 3.42293444 |
47 | * CENP-A containing nucleosome assembly (GO:0034080) | 3.39958522 |
48 | regulation of mitotic spindle organization (GO:0060236) | 3.39244614 |
49 | * DNA replication-independent nucleosome assembly (GO:0006336) | 3.39191559 |
50 | * DNA replication-independent nucleosome organization (GO:0034724) | 3.39191559 |
51 | protein localization to chromosome (GO:0034502) | 3.38124161 |
52 | establishment of chromosome localization (GO:0051303) | 3.37682556 |
53 | spindle checkpoint (GO:0031577) | 3.37490166 |
54 | negative regulation of histone methylation (GO:0031061) | 3.37366284 |
55 | regulation of centriole replication (GO:0046599) | 3.35635963 |
56 | DNA strand elongation (GO:0022616) | 3.32286039 |
57 | heterochromatin organization (GO:0070828) | 3.31435345 |
58 | mitotic recombination (GO:0006312) | 3.31406001 |
59 | regulation of centrosome cycle (GO:0046605) | 3.26265624 |
60 | regulation of chromosome segregation (GO:0051983) | 3.25278769 |
61 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.25169335 |
62 | regulation of DNA endoreduplication (GO:0032875) | 3.24975288 |
63 | DNA topological change (GO:0006265) | 3.23008030 |
64 | kinetochore assembly (GO:0051382) | 3.21201191 |
65 | mitotic spindle checkpoint (GO:0071174) | 3.20431767 |
66 | nucleobase biosynthetic process (GO:0046112) | 3.19058033 |
67 | * chromatin assembly or disassembly (GO:0006333) | 3.18927367 |
68 | IMP metabolic process (GO:0046040) | 3.18431376 |
69 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.17170436 |
70 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.17055583 |
71 | negative regulation of DNA recombination (GO:0045910) | 3.14891681 |
72 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.14073789 |
73 | telomere maintenance via recombination (GO:0000722) | 3.13431821 |
74 | spindle assembly checkpoint (GO:0071173) | 3.12974071 |
75 | protein K6-linked ubiquitination (GO:0085020) | 3.12705608 |
76 | * histone exchange (GO:0043486) | 3.12395027 |
77 | pre-miRNA processing (GO:0031054) | 3.12059429 |
78 | formation of translation preinitiation complex (GO:0001731) | 3.10032342 |
79 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.09838903 |
80 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.09817645 |
81 | histone H2A monoubiquitination (GO:0035518) | 3.09763885 |
82 | * chromatin assembly (GO:0031497) | 3.08916301 |
83 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.08358696 |
84 | regulation of sister chromatid segregation (GO:0033045) | 3.08358696 |
85 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.08358696 |
86 | negative regulation of chromosome segregation (GO:0051985) | 3.07229778 |
87 | DNA conformation change (GO:0071103) | 3.07199520 |
88 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.04657825 |
89 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.04117907 |
90 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.04117907 |
91 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.04117907 |
92 | negative regulation of sister chromatid segregation (GO:0033046) | 3.04117907 |
93 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.03997171 |
94 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.03865977 |
95 | mitotic spindle assembly checkpoint (GO:0007094) | 3.02896913 |
96 | nuclear envelope organization (GO:0006998) | 3.02671797 |
97 | * ATP-dependent chromatin remodeling (GO:0043044) | 3.01282610 |
98 | purine nucleobase biosynthetic process (GO:0009113) | 2.98418505 |
99 | protein complex localization (GO:0031503) | 2.97669919 |
100 | nucleosome disassembly (GO:0006337) | 2.97660844 |
101 | protein-DNA complex disassembly (GO:0032986) | 2.97660844 |
102 | negative regulation of DNA repair (GO:0045738) | 2.96173280 |
103 | chromosome segregation (GO:0007059) | 2.96047637 |
104 | sister chromatid cohesion (GO:0007062) | 2.94456659 |
105 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.94385550 |
106 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.91224879 |
107 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.91224879 |
108 | DNA damage response, detection of DNA damage (GO:0042769) | 2.91194590 |
109 | mRNA transport (GO:0051028) | 2.90426088 |
110 | regulation of centrosome duplication (GO:0010824) | 2.89996430 |
111 | DNA double-strand break processing (GO:0000729) | 2.89813213 |
112 | translesion synthesis (GO:0019985) | 2.89669280 |
113 | regulation of gene silencing by miRNA (GO:0060964) | 2.89157721 |
114 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.87537353 |
115 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.87537353 |
116 | negative regulation of fibroblast apoptotic process (GO:2000270) | 2.85620318 |
117 | negative regulation of RNA splicing (GO:0033119) | 2.85364980 |
118 | mitotic spindle organization (GO:0007052) | 2.81927986 |
119 | V(D)J recombination (GO:0033151) | 2.80609816 |
120 | RNA-dependent DNA replication (GO:0006278) | 2.77352644 |
121 | mitotic G2/M transition checkpoint (GO:0044818) | 2.76201419 |
122 | termination of RNA polymerase II transcription (GO:0006369) | 2.76096883 |
123 | negative regulation of mRNA processing (GO:0050686) | 2.74290485 |
124 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.72503277 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.33571884 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.51232779 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.62054800 |
4 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.49946429 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.39731138 |
6 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 3.02406959 |
7 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.64865064 |
8 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.63031969 |
9 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.61262430 |
10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.53340770 |
11 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.50388702 |
12 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.44375228 |
13 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.33634273 |
14 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.27640525 |
15 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.26210318 |
16 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.10314776 |
17 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.7860926 |
18 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.93153626 |
19 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.92643384 |
20 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.91233012 |
21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.90946603 |
22 | EWS_26573619_Chip-Seq_HEK293_Human | 1.89492984 |
23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.84835348 |
24 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.84793171 |
25 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.84718941 |
26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.84276030 |
27 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.83655118 |
28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.83285033 |
29 | * CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.82421819 |
30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.80969204 |
31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.79908619 |
32 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.79884045 |
33 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.69560982 |
34 | MYC_22102868_ChIP-Seq_BL_Human | 1.69092358 |
35 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.67088322 |
36 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.64644563 |
37 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.63274954 |
38 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.62816703 |
39 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.62273670 |
40 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.59964603 |
41 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.55354149 |
42 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.55237995 |
43 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.54272717 |
44 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.51922226 |
45 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.48455083 |
46 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.48029451 |
47 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.47996486 |
48 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.45985140 |
49 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.45568343 |
50 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.40987520 |
51 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.40330982 |
52 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.40330982 |
53 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.40330982 |
54 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.39918661 |
55 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.39722940 |
56 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.39457772 |
57 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.39269801 |
58 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.37005022 |
59 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.36727061 |
60 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.36090551 |
61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.34093409 |
62 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.33529049 |
63 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.31811014 |
64 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.28235146 |
65 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.24209940 |
66 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.23170885 |
67 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22889141 |
68 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.22713488 |
69 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.20793975 |
70 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.19304880 |
71 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.18314723 |
72 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.17589485 |
73 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.16858321 |
74 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.16658023 |
75 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.14559403 |
76 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.14481328 |
77 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.13489087 |
78 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.13305499 |
79 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.13157329 |
80 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.11203203 |
81 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09726662 |
82 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08436454 |
83 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.08297849 |
84 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.06995149 |
85 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.06360354 |
86 | * RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.06171775 |
87 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.05474447 |
88 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 1.03976174 |
89 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.03382094 |
90 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03304400 |
91 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.00214331 |
92 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.99163973 |
93 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.97347417 |
94 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.96889465 |
95 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.95747524 |
96 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.95670545 |
97 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.95554609 |
98 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.95360809 |
99 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.94958127 |
100 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.94762116 |
101 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.94255293 |
102 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.94128560 |
103 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.93797806 |
104 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.92506126 |
105 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.92155404 |
106 | P300_19829295_ChIP-Seq_ESCs_Human | 0.90706283 |
107 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.89824952 |
108 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.89725557 |
109 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.88764332 |
110 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.87980602 |
111 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.87827823 |
112 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.87672215 |
113 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.87584693 |
114 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.87091659 |
115 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.86388662 |
116 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.86351736 |
117 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.84743586 |
118 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.84255557 |
119 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.83596919 |
120 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.83574360 |
121 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.80920790 |
122 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.80104126 |
123 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.79825979 |
124 | MYB_26560356_Chip-Seq_TH1_Human | 0.79256111 |
125 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.79119455 |
126 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.77126052 |
127 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.76720798 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 4.29007947 |
2 | MP0010094_abnormal_chromosome_stability | 4.15315461 |
3 | MP0003693_abnormal_embryo_hatching | 4.04468179 |
4 | MP0003111_abnormal_nucleus_morphology | 3.66186772 |
5 | * MP0004957_abnormal_blastocyst_morpholog | 3.46184786 |
6 | MP0003077_abnormal_cell_cycle | 3.45204850 |
7 | MP0010352_gastrointestinal_tract_polyps | 2.84880407 |
8 | MP0008058_abnormal_DNA_repair | 2.75635992 |
9 | MP0008007_abnormal_cellular_replicative | 2.75571788 |
10 | MP0008877_abnormal_DNA_methylation | 2.64505746 |
11 | MP0003123_paternal_imprinting | 2.61987564 |
12 | MP0010307_abnormal_tumor_latency | 2.49339606 |
13 | * MP0001730_embryonic_growth_arrest | 2.19359463 |
14 | MP0000350_abnormal_cell_proliferation | 2.16999066 |
15 | MP0005076_abnormal_cell_differentiation | 1.96839701 |
16 | MP0002396_abnormal_hematopoietic_system | 1.94213897 |
17 | * MP0008932_abnormal_embryonic_tissue | 1.94078214 |
18 | MP0003121_genomic_imprinting | 1.91802240 |
19 | MP0003786_premature_aging | 1.79951877 |
20 | MP0002084_abnormal_developmental_patter | 1.76874078 |
21 | MP0003221_abnormal_cardiomyocyte_apopto | 1.75621157 |
22 | MP0004197_abnormal_fetal_growth/weight/ | 1.74946060 |
23 | * MP0005380_embryogenesis_phenotype | 1.74857953 |
24 | * MP0001672_abnormal_embryogenesis/_devel | 1.74857953 |
25 | MP0004808_abnormal_hematopoietic_stem | 1.70185989 |
26 | MP0001697_abnormal_embryo_size | 1.68417381 |
27 | MP0005394_taste/olfaction_phenotype | 1.67126706 |
28 | MP0005499_abnormal_olfactory_system | 1.67126706 |
29 | MP0001188_hyperpigmentation | 1.63622524 |
30 | MP0003984_embryonic_growth_retardation | 1.60630253 |
31 | MP0000490_abnormal_crypts_of | 1.60292894 |
32 | * MP0002085_abnormal_embryonic_tissue | 1.59628075 |
33 | MP0003890_abnormal_embryonic-extraembry | 1.58212081 |
34 | MP0002088_abnormal_embryonic_growth/wei | 1.57940108 |
35 | MP0002233_abnormal_nose_morphology | 1.57768635 |
36 | MP0008789_abnormal_olfactory_epithelium | 1.57141502 |
37 | * MP0002086_abnormal_extraembryonic_tissu | 1.55394977 |
38 | MP0005187_abnormal_penis_morphology | 1.49884085 |
39 | MP0009697_abnormal_copulation | 1.49795348 |
40 | MP0000537_abnormal_urethra_morphology | 1.49568050 |
41 | MP0003567_abnormal_fetal_cardiomyocyte | 1.49401231 |
42 | MP0003385_abnormal_body_wall | 1.48754346 |
43 | MP0001529_abnormal_vocalization | 1.48451923 |
44 | MP0001293_anophthalmia | 1.44893879 |
45 | MP0000778_abnormal_nervous_system | 1.43053517 |
46 | MP0001299_abnormal_eye_distance/ | 1.43029588 |
47 | * MP0002080_prenatal_lethality | 1.41580213 |
48 | MP0002009_preneoplasia | 1.34695475 |
49 | MP0002877_abnormal_melanocyte_morpholog | 1.34645878 |
50 | MP0003122_maternal_imprinting | 1.34211291 |
51 | MP0003861_abnormal_nervous_system | 1.33785400 |
52 | MP0003705_abnormal_hypodermis_morpholog | 1.32976654 |
53 | MP0006072_abnormal_retinal_apoptosis | 1.30111565 |
54 | MP0003937_abnormal_limbs/digits/tail_de | 1.27467597 |
55 | MP0003787_abnormal_imprinting | 1.25824832 |
56 | MP0002210_abnormal_sex_determination | 1.25197415 |
57 | MP0009053_abnormal_anal_canal | 1.22088509 |
58 | MP0010234_abnormal_vibrissa_follicle | 1.21897854 |
59 | MP0000049_abnormal_middle_ear | 1.18974269 |
60 | MP0005248_abnormal_Harderian_gland | 1.18387948 |
61 | * MP0000313_abnormal_cell_death | 1.16394917 |
62 | MP0002019_abnormal_tumor_incidence | 1.15919590 |
63 | MP0010030_abnormal_orbit_morphology | 1.14307039 |
64 | MP0000569_abnormal_digit_pigmentation | 1.13183539 |
65 | MP0000647_abnormal_sebaceous_gland | 1.10747351 |
66 | MP0002751_abnormal_autonomic_nervous | 1.10446021 |
67 | MP0003941_abnormal_skin_development | 1.09392637 |
68 | MP0001145_abnormal_male_reproductive | 1.09156417 |
69 | MP0002006_tumorigenesis | 1.05734114 |
70 | MP0009703_decreased_birth_body | 1.04355668 |
71 | MP0000428_abnormal_craniofacial_morphol | 1.01767471 |
72 | MP0005391_vision/eye_phenotype | 0.99995588 |
73 | MP0000733_abnormal_muscle_development | 0.99553149 |
74 | MP0000703_abnormal_thymus_morphology | 0.99214207 |
75 | MP0003763_abnormal_thymus_physiology | 0.99135497 |
76 | MP0001177_atelectasis | 0.98796426 |
77 | MP0000631_abnormal_neuroendocrine_gland | 0.97082534 |
78 | MP0002092_abnormal_eye_morphology | 0.96853882 |
79 | MP0000566_synostosis | 0.96839321 |
80 | MP0002166_altered_tumor_susceptibility | 0.95308337 |
81 | MP0001929_abnormal_gametogenesis | 0.94580683 |
82 | MP0006054_spinal_hemorrhage | 0.94261422 |
83 | MP0005397_hematopoietic_system_phenotyp | 0.94239804 |
84 | MP0001545_abnormal_hematopoietic_system | 0.94239804 |
85 | MP0000653_abnormal_sex_gland | 0.93456674 |
86 | MP0002081_perinatal_lethality | 0.93274578 |
87 | MP0003315_abnormal_perineum_morphology | 0.91965011 |
88 | MP0001915_intracranial_hemorrhage | 0.91465787 |
89 | MP0009672_abnormal_birth_weight | 0.91150462 |
90 | MP0003718_maternal_effect | 0.91079680 |
91 | MP0001286_abnormal_eye_development | 0.90944640 |
92 | MP0003566_abnormal_cell_adhesion | 0.90609680 |
93 | MP0000432_abnormal_head_morphology | 0.89614282 |
94 | MP0002697_abnormal_eye_size | 0.87307763 |
95 | MP0005623_abnormal_meninges_morphology | 0.86941296 |
96 | MP0001849_ear_inflammation | 0.85908867 |
97 | MP0002111_abnormal_tail_morphology | 0.84725850 |
98 | MP0004133_heterotaxia | 0.82125964 |
99 | MP0002398_abnormal_bone_marrow | 0.80964393 |
100 | MP0003119_abnormal_digestive_system | 0.80937144 |
101 | MP0002160_abnormal_reproductive_system | 0.79225052 |
102 | MP0001119_abnormal_female_reproductive | 0.78524268 |
103 | MP0002102_abnormal_ear_morphology | 0.78049012 |
104 | MP0003935_abnormal_craniofacial_develop | 0.77735456 |
105 | MP0010678_abnormal_skin_adnexa | 0.76793247 |
106 | MP0005389_reproductive_system_phenotype | 0.75998347 |
107 | MP0002152_abnormal_brain_morphology | 0.75511329 |
108 | MP0004811_abnormal_neuron_physiology | 0.75431430 |
109 | MP0003942_abnormal_urinary_system | 0.74708950 |
110 | MP0003136_yellow_coat_color | 0.74566098 |
111 | MP0009278_abnormal_bone_marrow | 0.74489013 |
112 | MP0008995_early_reproductive_senescence | 0.74416795 |
113 | MP0000516_abnormal_urinary_system | 0.73965086 |
114 | MP0005367_renal/urinary_system_phenotyp | 0.73965086 |
115 | MP0002254_reproductive_system_inflammat | 0.73203495 |
116 | MP0005621_abnormal_cell_physiology | 0.72775730 |
117 | MP0002925_abnormal_cardiovascular_devel | 0.72751988 |
118 | MP0000955_abnormal_spinal_cord | 0.72624457 |
119 | MP0003755_abnormal_palate_morphology | 0.70804884 |
120 | MP0003115_abnormal_respiratory_system | 0.70364021 |
121 | MP0002722_abnormal_immune_system | 0.69690950 |
122 | MP0000383_abnormal_hair_follicle | 0.69528469 |
123 | MP0009333_abnormal_splenocyte_physiolog | 0.68783572 |
124 | MP0003448_altered_tumor_morphology | 0.68363650 |
125 | MP0005023_abnormal_wound_healing | 0.68214159 |
126 | MP0005384_cellular_phenotype | 0.66998328 |
127 | MP0001340_abnormal_eyelid_morphology | 0.66255201 |
128 | MP0000477_abnormal_intestine_morphology | 0.65917927 |
129 | MP0002177_abnormal_outer_ear | 0.65622946 |
130 | MP0002234_abnormal_pharynx_morphology | 0.64486545 |
131 | MP0002114_abnormal_axial_skeleton | 0.64113141 |
132 | MP0006292_abnormal_olfactory_placode | 0.63374704 |
133 | MP0002938_white_spotting | 0.62372596 |
134 | MP0000858_altered_metastatic_potential | 0.60880592 |
135 | MP0000689_abnormal_spleen_morphology | 0.60761861 |
136 | MP0003936_abnormal_reproductive_system | 0.60578604 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromsome breakage (HP:0040012) | 4.30552925 |
2 | Cortical dysplasia (HP:0002539) | 4.02502285 |
3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.84542307 |
4 | Volvulus (HP:0002580) | 3.71042711 |
5 | Abnormality of chromosome stability (HP:0003220) | 3.58181506 |
6 | Hepatoblastoma (HP:0002884) | 3.57247778 |
7 | Birth length less than 3rd percentile (HP:0003561) | 3.51583613 |
8 | Colon cancer (HP:0003003) | 3.13821128 |
9 | Medulloblastoma (HP:0002885) | 3.12733809 |
10 | Selective tooth agenesis (HP:0001592) | 3.11667561 |
11 | Ependymoma (HP:0002888) | 3.02148937 |
12 | Meckel diverticulum (HP:0002245) | 2.95187259 |
13 | Abnormality of the labia minora (HP:0012880) | 2.86388195 |
14 | Ectopic kidney (HP:0000086) | 2.84249784 |
15 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.82796160 |
16 | Deviation of the thumb (HP:0009603) | 2.81975581 |
17 | Abnormality of the preputium (HP:0100587) | 2.80694033 |
18 | Proximal placement of thumb (HP:0009623) | 2.78374563 |
19 | Abnormality of the ileum (HP:0001549) | 2.74591574 |
20 | 11 pairs of ribs (HP:0000878) | 2.71607603 |
21 | Rhabdomyosarcoma (HP:0002859) | 2.71346886 |
22 | Impulsivity (HP:0100710) | 2.65896149 |
23 | Increased nuchal translucency (HP:0010880) | 2.64477271 |
24 | Patellar aplasia (HP:0006443) | 2.61649860 |
25 | Myelodysplasia (HP:0002863) | 2.59299374 |
26 | Biliary tract neoplasm (HP:0100574) | 2.55488970 |
27 | Duodenal stenosis (HP:0100867) | 2.53327794 |
28 | Small intestinal stenosis (HP:0012848) | 2.53327794 |
29 | Missing ribs (HP:0000921) | 2.50785210 |
30 | Intestinal atresia (HP:0011100) | 2.46512909 |
31 | Breast hypoplasia (HP:0003187) | 2.43354624 |
32 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.42955790 |
33 | Agnosia (HP:0010524) | 2.40998420 |
34 | Abnormality of the astrocytes (HP:0100707) | 2.38004835 |
35 | Astrocytoma (HP:0009592) | 2.38004835 |
36 | Reticulocytopenia (HP:0001896) | 2.36947656 |
37 | Thyroid carcinoma (HP:0002890) | 2.36385879 |
38 | Neoplasm of the oral cavity (HP:0100649) | 2.30963704 |
39 | Shoulder girdle muscle weakness (HP:0003547) | 2.29116749 |
40 | Basal cell carcinoma (HP:0002671) | 2.26181714 |
41 | Absent radius (HP:0003974) | 2.22622631 |
42 | Amaurosis fugax (HP:0100576) | 2.21826757 |
43 | Transitional cell carcinoma of the bladder (HP:0006740) | 2.20771632 |
44 | Glioma (HP:0009733) | 2.18562953 |
45 | High anterior hairline (HP:0009890) | 2.18265558 |
46 | Abnormality of the carotid arteries (HP:0005344) | 2.17189164 |
47 | Prominent nose (HP:0000448) | 2.16363784 |
48 | Embryonal neoplasm (HP:0002898) | 2.14997112 |
49 | Facial hemangioma (HP:0000329) | 2.14438768 |
50 | Uterine leiomyosarcoma (HP:0002891) | 2.13422685 |
51 | Leiomyosarcoma (HP:0100243) | 2.13422685 |
52 | Insidious onset (HP:0003587) | 2.13234743 |
53 | Termporal pattern (HP:0011008) | 2.13234743 |
54 | Sloping forehead (HP:0000340) | 2.13036575 |
55 | Cutaneous melanoma (HP:0012056) | 2.12526435 |
56 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.10590198 |
57 | Supernumerary spleens (HP:0009799) | 2.10541395 |
58 | Gastrointestinal carcinoma (HP:0002672) | 2.10377904 |
59 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.10377904 |
60 | Abnormality of the duodenum (HP:0002246) | 2.08833504 |
61 | Atresia of the external auditory canal (HP:0000413) | 2.08221556 |
62 | Short 4th metacarpal (HP:0010044) | 2.07270341 |
63 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.07270341 |
64 | Acute myeloid leukemia (HP:0004808) | 2.06678121 |
65 | Neoplasm of the pancreas (HP:0002894) | 2.06081530 |
66 | Aplasia involving forearm bones (HP:0009822) | 2.05612018 |
67 | Absent forearm bone (HP:0003953) | 2.05612018 |
68 | Cafe-au-lait spot (HP:0000957) | 2.05532430 |
69 | Degeneration of anterior horn cells (HP:0002398) | 2.04793118 |
70 | Abnormality of the anterior horn cell (HP:0006802) | 2.04793118 |
71 | Absent thumb (HP:0009777) | 2.02768593 |
72 | Abnormality of the fingertips (HP:0001211) | 2.02438199 |
73 | Spastic diplegia (HP:0001264) | 2.01884890 |
74 | Long eyelashes (HP:0000527) | 2.01262189 |
75 | Bladder carcinoma (HP:0002862) | 2.00682094 |
76 | Bladder neoplasm (HP:0009725) | 2.00682094 |
77 | Embryonal renal neoplasm (HP:0011794) | 2.00600689 |
78 | Abnormal lung lobation (HP:0002101) | 1.99952463 |
79 | Septo-optic dysplasia (HP:0100842) | 1.99704549 |
80 | Abnormal number of incisors (HP:0011064) | 1.98171183 |
81 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.97931789 |
82 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.97931789 |
83 | Pelvic girdle muscle weakness (HP:0003749) | 1.96995228 |
84 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.94232257 |
85 | Neoplasm of the small intestine (HP:0100833) | 1.93578722 |
86 | Neoplasm of striated muscle (HP:0009728) | 1.92958069 |
87 | Sandal gap (HP:0001852) | 1.92457564 |
88 | Squamous cell carcinoma (HP:0002860) | 1.90714610 |
89 | Abnormality of chromosome segregation (HP:0002916) | 1.88652960 |
90 | Neoplasm of the adrenal cortex (HP:0100641) | 1.85691878 |
91 | Deep philtrum (HP:0002002) | 1.85158180 |
92 | Abnormal hair whorl (HP:0010721) | 1.84623292 |
93 | Clubbing of toes (HP:0100760) | 1.84087421 |
94 | Ovarian neoplasm (HP:0100615) | 1.82480288 |
95 | Bone marrow hypocellularity (HP:0005528) | 1.81453898 |
96 | Supernumerary ribs (HP:0005815) | 1.80173551 |
97 | Tracheoesophageal fistula (HP:0002575) | 1.77282103 |
98 | Breast carcinoma (HP:0003002) | 1.75200158 |
99 | Duplicated collecting system (HP:0000081) | 1.75171005 |
100 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.74524307 |
101 | Abnormality of the septum pellucidum (HP:0007375) | 1.74010889 |
102 | Blepharitis (HP:0000498) | 1.73924897 |
103 | Abnormality of the antihelix (HP:0009738) | 1.73857301 |
104 | Carpal bone hypoplasia (HP:0001498) | 1.73122926 |
105 | Short thumb (HP:0009778) | 1.73055971 |
106 | Abnormal biliary tract morphology (HP:0012440) | 1.72928158 |
107 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.72387626 |
108 | Trigonocephaly (HP:0000243) | 1.71414499 |
109 | High pitched voice (HP:0001620) | 1.71288694 |
110 | Horseshoe kidney (HP:0000085) | 1.70907723 |
111 | Neoplasm of the colon (HP:0100273) | 1.70652849 |
112 | Overlapping toe (HP:0001845) | 1.70443618 |
113 | Generalized hypotonia (HP:0001290) | 1.70384958 |
114 | Papillary thyroid carcinoma (HP:0002895) | 1.69541375 |
115 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.69362691 |
116 | Cutaneous syndactyly (HP:0012725) | 1.69159508 |
117 | Multiple enchondromatosis (HP:0005701) | 1.69114381 |
118 | Abnormality of the calcaneus (HP:0008364) | 1.68848069 |
119 | Cutis marmorata (HP:0000965) | 1.68486013 |
120 | Uterine neoplasm (HP:0010784) | 1.68455006 |
121 | Arteriovenous malformation (HP:0100026) | 1.67769098 |
122 | Duplication of thumb phalanx (HP:0009942) | 1.67731208 |
123 | Triphalangeal thumb (HP:0001199) | 1.67627384 |
124 | Partial agenesis of the corpus callosum (HP:0001338) | 1.67201574 |
125 | Truncal obesity (HP:0001956) | 1.67082823 |
126 | Oral leukoplakia (HP:0002745) | 1.66902764 |
127 | Micropenis (HP:0000054) | 1.66827701 |
128 | Subacute progressive viral hepatitis (HP:0006572) | 1.66681428 |
129 | Gastrointestinal atresia (HP:0002589) | 1.66490812 |
130 | Stenosis of the external auditory canal (HP:0000402) | 1.66015159 |
131 | Cystic hygroma (HP:0000476) | 1.65970910 |
132 | Bifid tongue (HP:0010297) | 1.65305029 |
133 | Absent eyebrow (HP:0002223) | 1.64973444 |
134 | Skull defect (HP:0001362) | 1.64860655 |
135 | Genital tract atresia (HP:0001827) | 1.64620052 |
136 | Spinal cord lesions (HP:0100561) | 1.64131438 |
137 | Syringomyelia (HP:0003396) | 1.64131438 |
138 | Low anterior hairline (HP:0000294) | 1.63721398 |
139 | Vaginal atresia (HP:0000148) | 1.63326404 |
140 | Cutaneous finger syndactyly (HP:0010554) | 1.63244098 |
141 | Abnormality of DNA repair (HP:0003254) | 1.62664158 |
142 | Drooling (HP:0002307) | 1.62522297 |
143 | Obsessive-compulsive behavior (HP:0000722) | 1.61959949 |
144 | Broad foot (HP:0001769) | 1.59054398 |
145 | Facial cleft (HP:0002006) | 1.56236784 |
146 | Hyperglycinemia (HP:0002154) | 1.56137159 |
147 | Omphalocele (HP:0001539) | 1.55441025 |
148 | Esophageal atresia (HP:0002032) | 1.52914831 |
149 | Renal hypoplasia (HP:0000089) | 1.50632208 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 4.70549630 |
2 | CDK12 | 3.72106291 |
3 | WEE1 | 3.60406951 |
4 | NEK2 | 2.86787614 |
5 | SRPK1 | 2.75796199 |
6 | MKNK1 | 2.73998700 |
7 | TRIM28 | 2.54886746 |
8 | BUB1 | 2.51599837 |
9 | TTK | 2.34644805 |
10 | MKNK2 | 2.29106089 |
11 | MAP3K4 | 2.20650385 |
12 | BRSK2 | 2.12517376 |
13 | TSSK6 | 2.03981899 |
14 | ACVR1B | 1.95253151 |
15 | EIF2AK1 | 1.95155452 |
16 | PLK1 | 1.88117091 |
17 | ATR | 1.84395086 |
18 | RPS6KB2 | 1.83725379 |
19 | PLK3 | 1.81316631 |
20 | AURKB | 1.75742888 |
21 | PASK | 1.73768430 |
22 | CDK7 | 1.68234965 |
23 | LATS1 | 1.66909340 |
24 | EEF2K | 1.66580050 |
25 | BRD4 | 1.64069013 |
26 | PLK4 | 1.62505651 |
27 | TAF1 | 1.59470625 |
28 | TNIK | 1.56148743 |
29 | CHEK1 | 1.54670461 |
30 | CDK4 | 1.54592084 |
31 | RPS6KA4 | 1.54550423 |
32 | EPHA2 | 1.51707904 |
33 | DYRK3 | 1.49583495 |
34 | STK10 | 1.49471152 |
35 | STK3 | 1.47599927 |
36 | NEK1 | 1.45823093 |
37 | CHEK2 | 1.45251360 |
38 | MAP2K7 | 1.41255348 |
39 | CDK6 | 1.39962097 |
40 | STK4 | 1.38796916 |
41 | ZAK | 1.36909132 |
42 | ALK | 1.36854401 |
43 | TLK1 | 1.35270852 |
44 | ATM | 1.32012394 |
45 | PNCK | 1.29887968 |
46 | MAP3K8 | 1.25790022 |
47 | SCYL2 | 1.20700767 |
48 | CASK | 1.16638442 |
49 | MAP3K10 | 1.15767508 |
50 | CSNK1G2 | 1.15474263 |
51 | MELK | 1.14670885 |
52 | PKN2 | 1.14534321 |
53 | EIF2AK3 | 1.11763782 |
54 | WNK3 | 1.07521232 |
55 | VRK1 | 1.06209991 |
56 | PIM1 | 1.03801113 |
57 | CSNK1G3 | 1.02244258 |
58 | * CDK2 | 1.01998520 |
59 | TGFBR1 | 1.00395514 |
60 | LATS2 | 0.97193342 |
61 | YES1 | 0.92848701 |
62 | PLK2 | 0.91916191 |
63 | BRSK1 | 0.89231490 |
64 | CDK9 | 0.88340107 |
65 | STK24 | 0.85238250 |
66 | NUAK1 | 0.84933381 |
67 | CDK1 | 0.81900008 |
68 | RPS6KA5 | 0.79314536 |
69 | ERBB3 | 0.79262683 |
70 | PAK4 | 0.77541946 |
71 | DYRK2 | 0.76894108 |
72 | KSR1 | 0.74543189 |
73 | UHMK1 | 0.74085443 |
74 | MTOR | 0.73714839 |
75 | AURKA | 0.73390883 |
76 | CDK19 | 0.70676558 |
77 | CSNK1D | 0.67520037 |
78 | CHUK | 0.67467488 |
79 | FRK | 0.66190976 |
80 | DYRK1B | 0.66178455 |
81 | CSNK2A2 | 0.65929535 |
82 | CDK3 | 0.65452012 |
83 | MST4 | 0.63030413 |
84 | CAMK1G | 0.61021385 |
85 | CDK18 | 0.59063800 |
86 | MARK3 | 0.59000360 |
87 | FGFR1 | 0.57745678 |
88 | PRKDC | 0.57259367 |
89 | STK38L | 0.56587440 |
90 | CDK14 | 0.56327043 |
91 | CSNK1E | 0.54791905 |
92 | PBK | 0.54371456 |
93 | NME2 | 0.52622542 |
94 | FGFR3 | 0.51517005 |
95 | EIF2AK2 | 0.51230934 |
96 | PTK6 | 0.50342979 |
97 | CDK15 | 0.50123767 |
98 | SIK3 | 0.50119954 |
99 | EPHA3 | 0.48665160 |
100 | CDK11A | 0.48269063 |
101 | CSNK2A1 | 0.48069040 |
102 | LRRK2 | 0.47715108 |
103 | CLK1 | 0.47511949 |
104 | ERBB4 | 0.47498985 |
105 | MINK1 | 0.47317232 |
106 | TIE1 | 0.46124348 |
107 | PAK2 | 0.45585117 |
108 | * MAPK14 | 0.45274842 |
109 | TRPM7 | 0.44540150 |
110 | DYRK1A | 0.44202658 |
111 | JAK3 | 0.43933010 |
112 | BRAF | 0.41618327 |
113 | RPS6KB1 | 0.41605809 |
114 | NEK9 | 0.41530248 |
115 | FLT3 | 0.40784722 |
116 | CSNK1A1L | 0.40528108 |
117 | AKT3 | 0.38996157 |
118 | MAP4K1 | 0.38865465 |
119 | MAPK10 | 0.38308568 |
120 | TTN | 0.36654287 |
121 | CAMK1D | 0.36583045 |
122 | TESK2 | 0.36373425 |
123 | EGFR | 0.36364339 |
124 | CDK8 | 0.35953334 |
125 | PDGFRA | 0.35231469 |
126 | AKT1 | 0.33962872 |
127 | ICK | 0.33669609 |
128 | MAPK1 | 0.32633514 |
129 | GSK3B | 0.31079270 |
130 | CSNK1G1 | 0.29837301 |
131 | BMX | 0.29741233 |
132 | MET | 0.29371796 |
133 | TEC | 0.28656350 |
134 | BCR | 0.27424037 |
135 | FGFR2 | 0.26771178 |
136 | PDGFRB | 0.26174858 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.90160643 |
2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.62472720 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.58886397 |
4 | RNA transport_Homo sapiens_hsa03013 | 3.28937197 |
5 | Cell cycle_Homo sapiens_hsa04110 | 3.13573918 |
6 | Spliceosome_Homo sapiens_hsa03040 | 3.11437309 |
7 | Homologous recombination_Homo sapiens_hsa03440 | 2.61816120 |
8 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.59981428 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.48734629 |
10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.44861985 |
11 | Base excision repair_Homo sapiens_hsa03410 | 2.38700527 |
12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.38047055 |
13 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.35344878 |
14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.35258547 |
15 | RNA polymerase_Homo sapiens_hsa03020 | 2.27511757 |
16 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.08040888 |
17 | RNA degradation_Homo sapiens_hsa03018 | 2.07866998 |
18 | Basal transcription factors_Homo sapiens_hsa03022 | 2.03584520 |
19 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.99787159 |
20 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.87411279 |
21 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.83765044 |
22 | Protein export_Homo sapiens_hsa03060 | 1.80379215 |
23 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.54245434 |
24 | Ribosome_Homo sapiens_hsa03010 | 1.52778585 |
25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.51603394 |
26 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.49349256 |
27 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.36857063 |
28 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.35322056 |
29 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.31906002 |
30 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.28236106 |
31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.27953318 |
32 | Proteasome_Homo sapiens_hsa03050 | 1.25897236 |
33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.23596730 |
34 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.15888468 |
35 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15855388 |
36 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.13969199 |
37 | HTLV-I infection_Homo sapiens_hsa05166 | 1.12394648 |
38 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.10981531 |
39 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.08041987 |
40 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.05726948 |
41 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.99305627 |
42 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.98085934 |
43 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.91622350 |
44 | Thyroid cancer_Homo sapiens_hsa05216 | 0.90650655 |
45 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.89654636 |
46 | Adherens junction_Homo sapiens_hsa04520 | 0.87438692 |
47 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.87002903 |
48 | Colorectal cancer_Homo sapiens_hsa05210 | 0.85997716 |
49 | Alcoholism_Homo sapiens_hsa05034 | 0.84891281 |
50 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.82523092 |
51 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.82395197 |
52 | Prostate cancer_Homo sapiens_hsa05215 | 0.80958164 |
53 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.79810420 |
54 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.79214639 |
55 | Purine metabolism_Homo sapiens_hsa00230 | 0.78343078 |
56 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.77949930 |
57 | Hepatitis B_Homo sapiens_hsa05161 | 0.75616432 |
58 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.74569104 |
59 | Viral myocarditis_Homo sapiens_hsa05416 | 0.73379338 |
60 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.72258835 |
61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.71563816 |
62 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.71207926 |
63 | Legionellosis_Homo sapiens_hsa05134 | 0.70953002 |
64 | Measles_Homo sapiens_hsa05162 | 0.70471203 |
65 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.69641727 |
66 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.68932523 |
67 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.66179226 |
68 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.66112273 |
69 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.66000332 |
70 | Carbon metabolism_Homo sapiens_hsa01200 | 0.65746117 |
71 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.65154134 |
72 | Axon guidance_Homo sapiens_hsa04360 | 0.63507622 |
73 | Apoptosis_Homo sapiens_hsa04210 | 0.63217253 |
74 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.61850083 |
75 | Pathways in cancer_Homo sapiens_hsa05200 | 0.60089504 |
76 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.59952469 |
77 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.58733143 |
78 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.57855655 |
79 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.57426372 |
80 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.55803744 |
81 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.54482010 |
82 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.54248948 |
83 | Influenza A_Homo sapiens_hsa05164 | 0.52840575 |
84 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.50095970 |
85 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.49778637 |
86 | Tight junction_Homo sapiens_hsa04530 | 0.48985825 |
87 | Lysine degradation_Homo sapiens_hsa00310 | 0.48706222 |
88 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.47307509 |
89 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46620821 |
90 | Shigellosis_Homo sapiens_hsa05131 | 0.45895836 |
91 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.45008365 |
92 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.44725956 |
93 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.44527279 |
94 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.44014644 |
95 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.42965093 |
96 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.42733809 |
97 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.42094131 |
98 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.41618310 |
99 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.41187219 |
100 | Bladder cancer_Homo sapiens_hsa05219 | 0.39143896 |
101 | Circadian rhythm_Homo sapiens_hsa04710 | 0.39108386 |
102 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.38589659 |
103 | Melanoma_Homo sapiens_hsa05218 | 0.38588097 |
104 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.38469972 |
105 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.38282104 |
106 | Focal adhesion_Homo sapiens_hsa04510 | 0.37713136 |
107 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.37534738 |
108 | Gap junction_Homo sapiens_hsa04540 | 0.37466015 |
109 | Melanogenesis_Homo sapiens_hsa04916 | 0.37382465 |
110 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.35922711 |
111 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.35771391 |
112 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.35311794 |
113 | Leishmaniasis_Homo sapiens_hsa05140 | 0.34858801 |
114 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.33370209 |
115 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.33083128 |
116 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.32760692 |
117 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.32672825 |
118 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.32186244 |
119 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.30949643 |
120 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.30814457 |
121 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.29574992 |
122 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.29179575 |
123 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.29050428 |
124 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.28676534 |
125 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.28325911 |
126 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.27479733 |
127 | Allograft rejection_Homo sapiens_hsa05330 | 0.25905448 |
128 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.25677990 |
129 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.24856551 |
130 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.24339704 |
131 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.23513211 |
132 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.19955409 |
133 | Glioma_Homo sapiens_hsa05214 | 0.19341593 |
134 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.19102176 |
135 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.18847008 |