SMARCC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)4.84606426
2locomotory exploration behavior (GO:0035641)4.81662198
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.49028003
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.46217628
5layer formation in cerebral cortex (GO:0021819)4.37659222
6sodium ion export (GO:0071436)4.02906474
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.94812181
8vocalization behavior (GO:0071625)3.88268840
9synaptic vesicle docking involved in exocytosis (GO:0016081)3.70967014
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.63702503
11postsynaptic membrane organization (GO:0001941)3.61521950
12dendritic spine morphogenesis (GO:0060997)3.59990222
13synaptic vesicle exocytosis (GO:0016079)3.59748641
14glucocorticoid receptor signaling pathway (GO:0042921)3.54268527
15regulation of synaptic vesicle exocytosis (GO:2000300)3.48990982
16glutamate secretion (GO:0014047)3.48543537
17regulation of ARF protein signal transduction (GO:0032012)3.46805742
18regulation of glutamate receptor signaling pathway (GO:1900449)3.46753732
19dendrite morphogenesis (GO:0048813)3.45900339
20cellular potassium ion homeostasis (GO:0030007)3.44968253
21regulation of synapse structural plasticity (GO:0051823)3.43866394
22activation of protein kinase A activity (GO:0034199)3.41681868
23exploration behavior (GO:0035640)3.38177063
24cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.36017443
25cell communication by electrical coupling (GO:0010644)3.32738155
26positive regulation of CREB transcription factor activity (GO:0032793)3.27424728
27neurotransmitter secretion (GO:0007269)3.24364436
28cerebellar Purkinje cell differentiation (GO:0021702)3.22653811
29cytoskeletal anchoring at plasma membrane (GO:0007016)3.14850464
30establishment of nucleus localization (GO:0040023)3.09991464
31proline transport (GO:0015824)3.08184829
32protein localization to synapse (GO:0035418)3.06639051
33regulation of synaptic vesicle transport (GO:1902803)3.04983272
34regulation of neuronal synaptic plasticity (GO:0048168)3.04123013
35gamma-aminobutyric acid transport (GO:0015812)3.01627798
36ionotropic glutamate receptor signaling pathway (GO:0035235)3.01014029
37positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.00310136
38histone H3-K4 trimethylation (GO:0080182)2.99936612
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.95877726
40cerebellar Purkinje cell layer development (GO:0021680)2.95447455
41positive regulation of synapse maturation (GO:0090129)2.91332757
42glycine transport (GO:0015816)2.90028935
43regulation of long-term neuronal synaptic plasticity (GO:0048169)2.89419556
44cellular sodium ion homeostasis (GO:0006883)2.86438131
45neuromuscular process controlling balance (GO:0050885)2.85926873
46cytoplasmic mRNA processing body assembly (GO:0033962)2.85453141
47corticosteroid receptor signaling pathway (GO:0031958)2.84909740
48establishment of mitochondrion localization (GO:0051654)2.82490672
49axonal fasciculation (GO:0007413)2.81513723
50potassium ion import (GO:0010107)2.80792053
51regulation of axon extension involved in axon guidance (GO:0048841)2.80166686
52cell migration in hindbrain (GO:0021535)2.75731211
53neurotransmitter-gated ion channel clustering (GO:0072578)2.74496160
54neuron recognition (GO:0008038)2.74255202
55intracellular estrogen receptor signaling pathway (GO:0030520)2.72781707
56negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.72589897
57synaptic vesicle endocytosis (GO:0048488)2.71423995
58positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.71324285
59regulation of clathrin-mediated endocytosis (GO:2000369)2.71300645
60regulation of nucleobase-containing compound transport (GO:0032239)2.69658602
61long-term memory (GO:0007616)2.68065017
62regulation of RNA export from nucleus (GO:0046831)2.67397496
63presynaptic membrane assembly (GO:0097105)2.67304833
64potassium ion homeostasis (GO:0055075)2.67286493
65coronary vasculature morphogenesis (GO:0060977)2.66403844
66response to pheromone (GO:0019236)2.64110918
67presynaptic membrane organization (GO:0097090)2.63705784
68clathrin coat assembly (GO:0048268)2.63347809
69alanine transport (GO:0032328)2.62879365
70histone H3-K9 demethylation (GO:0033169)2.62057551
71histone lysine methylation (GO:0034968)2.60125329
72regulation of ARF GTPase activity (GO:0032312)2.59992393
73prepulse inhibition (GO:0060134)2.59051078
74membrane depolarization during action potential (GO:0086010)2.58660893
75histone H3-K4 methylation (GO:0051568)2.58284571
76regulation of histone H3-K27 methylation (GO:0061085)2.58247138
77synaptic transmission, glutamatergic (GO:0035249)2.57937013
78semaphorin-plexin signaling pathway (GO:0071526)2.57885544
79nerve growth factor signaling pathway (GO:0038180)2.57804580
80establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.57205181
81mitochondrion transport along microtubule (GO:0047497)2.57205181
82regulation of axon guidance (GO:1902667)2.55962546
83glutamate receptor signaling pathway (GO:0007215)2.55334668
84negative regulation of cytosolic calcium ion concentration (GO:0051481)2.55036833
85G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.54257727
86neuron cell-cell adhesion (GO:0007158)2.53322723
87cellular response to monoamine stimulus (GO:0071868)2.52468910
88cellular response to catecholamine stimulus (GO:0071870)2.52468910
89regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.51665164
90histone H3-K9 modification (GO:0061647)2.51413375
91regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.51301086
92regulation of dendritic spine morphogenesis (GO:0061001)2.51074729
93mating behavior (GO:0007617)2.50400696
94cell communication involved in cardiac conduction (GO:0086065)2.48850441
95vesicle transport along microtubule (GO:0047496)2.48323868
96insulin-like growth factor receptor signaling pathway (GO:0048009)2.48041799
97regulation of synapse maturation (GO:0090128)2.47291507
98regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.47140902
99camera-type eye morphogenesis (GO:0048593)2.46546779
100histone H3-K9 methylation (GO:0051567)2.46135638
101histone lysine demethylation (GO:0070076)2.45205230
102negative regulation of histone methylation (GO:0031061)2.44987403
103neurotransmitter transport (GO:0006836)2.42517959
104neuronal ion channel clustering (GO:0045161)2.42184834
105regulation of excitatory postsynaptic membrane potential (GO:0060079)2.42155982
106synapse assembly (GO:0007416)2.41226716
107astrocyte development (GO:0014002)2.39235030
108positive regulation of dendrite morphogenesis (GO:0050775)2.39094596
109membrane repolarization (GO:0086009)2.38867523
110cerebellar granule cell differentiation (GO:0021707)2.38398608
111negative regulation of cell size (GO:0045792)2.38334271
112pyrimidine nucleobase catabolic process (GO:0006208)2.38310120
113dendritic spine organization (GO:0097061)2.37289635
114histone demethylation (GO:0016577)2.37130318
115central nervous system projection neuron axonogenesis (GO:0021952)2.37014115
116auditory behavior (GO:0031223)2.36755359
117glial cell proliferation (GO:0014009)2.35005020
118suckling behavior (GO:0001967)2.34843458
119positive regulation of membrane potential (GO:0045838)2.34685198
120positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.33461902
121embryonic retina morphogenesis in camera-type eye (GO:0060059)2.33409720
122histone H3-K36 demethylation (GO:0070544)2.33020961
123innervation (GO:0060384)2.32696680
124negative regulation of erythrocyte differentiation (GO:0045647)2.31914229
125positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.31834901
126cell differentiation in hindbrain (GO:0021533)2.31662498
127response to auditory stimulus (GO:0010996)2.31441594
128regulation of postsynaptic membrane potential (GO:0060078)2.31288682
129membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.30476452
130positive regulation of gene expression, epigenetic (GO:0045815)2.30404087
131regulation of synaptic plasticity (GO:0048167)2.29589126
132organelle transport along microtubule (GO:0072384)2.29250721
133regulation of neurotransmitter levels (GO:0001505)2.28839179
134regulation of NFAT protein import into nucleus (GO:0051532)2.28461191
135positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.24993820
136retrograde transport, vesicle recycling within Golgi (GO:0000301)2.24737842
137response to catecholamine (GO:0071869)2.24702868
138response to monoamine (GO:0071867)2.24702868
139positive regulation of glycogen biosynthetic process (GO:0045725)2.24552287
140neuron-neuron synaptic transmission (GO:0007270)2.24183585
141protein targeting to Golgi (GO:0000042)2.24133310
142establishment of protein localization to Golgi (GO:0072600)2.23964747
143forebrain development (GO:0030900)2.23595238
144regulation of respiratory system process (GO:0044065)2.23417822
145neuronal action potential propagation (GO:0019227)2.22581036
146stress granule assembly (GO:0034063)2.20608947

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.16428987
2DROSHA_22980978_ChIP-Seq_HELA_Human2.66558965
3EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.49579150
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.32199468
5RNF2_18974828_ChIP-Seq_MESCs_Mouse2.23011162
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.23011162
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.21939659
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.18657676
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.12595265
10MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12281116
11* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.06075106
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.01611276
13MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.97797049
14MYC_22102868_ChIP-Seq_BL_Human1.96087623
15EZH2_27294783_Chip-Seq_ESCs_Mouse1.90262743
16SUZ12_27294783_Chip-Seq_ESCs_Mouse1.89920839
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.89885077
18REST_21632747_ChIP-Seq_MESCs_Mouse1.87091751
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.86797167
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.86346337
21RNF2_27304074_Chip-Seq_ESCs_Mouse1.85634812
22KDM2B_26808549_Chip-Seq_K562_Human1.82859871
23IKZF1_21737484_ChIP-ChIP_HCT116_Human1.76803275
24EZH2_27304074_Chip-Seq_ESCs_Mouse1.74614532
25CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.69782320
26WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.67970092
27TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.67643169
28KDM2B_26808549_Chip-Seq_SUP-B15_Human1.65285557
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.64962280
30GBX2_23144817_ChIP-Seq_PC3_Human1.57562910
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.55833189
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.55482619
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.55159452
34EED_16625203_ChIP-ChIP_MESCs_Mouse1.54591587
35* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.53242280
36* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.50508699
37DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.50038505
38KDM2B_26808549_Chip-Seq_DND41_Human1.48908689
39NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.47111644
40WT1_25993318_ChIP-Seq_PODOCYTE_Human1.47000004
41RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.45816526
42DNAJC2_21179169_ChIP-ChIP_NT2_Human1.43935202
43ERG_21242973_ChIP-ChIP_JURKAT_Human1.42200225
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.39404504
45* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.38865407
46VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.38682456
47RBPJ_22232070_ChIP-Seq_NCS_Mouse1.38251053
48KDM2B_26808549_Chip-Seq_JURKAT_Human1.37045716
49ZFP281_27345836_Chip-Seq_ESCs_Mouse1.36133750
50EGR1_19374776_ChIP-ChIP_THP-1_Human1.34511792
51VDR_21846776_ChIP-Seq_THP-1_Human1.34082860
52GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.32523204
53TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.30354704
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.30258455
55ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.28720272
56THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.27759956
57LXR_22292898_ChIP-Seq_THP-1_Human1.27334831
58* RING1B_27294783_Chip-Seq_ESCs_Mouse1.25318243
59AR_21572438_ChIP-Seq_LNCaP_Human1.23231919
60AR_19668381_ChIP-Seq_PC3_Human1.21386267
61GATA1_19941827_ChIP-Seq_MEL_Mouse1.20938387
62PKCTHETA_26484144_Chip-Seq_BREAST_Human1.19325331
63CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.17705570
64* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.17689090
65CBX2_27304074_Chip-Seq_ESCs_Mouse1.17605444
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.16842300
67* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.14819770
68AHR_22903824_ChIP-Seq_MCF-7_Human1.13853566
69TP53_23651856_ChIP-Seq_MEFs_Mouse1.13406845
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.12539919
71RUNX1_27514584_Chip-Seq_MCF-7_Human1.11302216
72SOX2_21211035_ChIP-Seq_LN229_Gbm1.09859597
73KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.09819762
74ARNT_22903824_ChIP-Seq_MCF-7_Human1.09298772
75* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08307870
76SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07983217
77RING1B_27294783_Chip-Seq_NPCs_Mouse1.07282677
78ZNF274_21170338_ChIP-Seq_K562_Hela1.07135925
79NR3C1_23031785_ChIP-Seq_PC12_Mouse1.06845686
80RACK7_27058665_Chip-Seq_MCF-7_Human1.06535338
81ESR1_15608294_ChIP-ChIP_MCF-7_Human1.06286925
82PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.03799330
83FOXA2_19822575_ChIP-Seq_HepG2_Human1.03129778
84NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.02906652
85ELK4_26923725_Chip-Seq_MESODERM_Mouse1.01995645
86OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.01298695
87BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.00373772
88CIITA_25753668_ChIP-Seq_RAJI_Human1.00321502
89TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.99785181
90* TCF7_22412390_ChIP-Seq_EML_Mouse0.99767169
91YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99418081
92SMAD4_21741376_ChIP-Seq_HESCs_Human0.97794844
93CREB1_26743006_Chip-Seq_LNCaP_Human0.97428047
94SMAD4_21799915_ChIP-Seq_A2780_Human0.97405805
95TP53_20018659_ChIP-ChIP_R1E_Mouse0.97311319
96SOX9_24532713_ChIP-Seq_HFSC_Mouse0.97033351
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96926627
98SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.96867295
99P300_27058665_Chip-Seq_ZR-75-30cells_Human0.96124409
100CTNNB1_20460455_ChIP-Seq_HCT116_Human0.95710400
101ESR2_21235772_ChIP-Seq_MCF-7_Human0.94843376
102CTCF_27219007_Chip-Seq_Bcells_Human0.94814052
103RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.94072564
104ISL1_27105846_Chip-Seq_CPCs_Mouse0.93764201
105SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92230220
106TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.91964625
107EP300_21415370_ChIP-Seq_HL-1_Mouse0.90314932
108RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.90291792
109TET1_21490601_ChIP-Seq_MESCs_Mouse0.88339236
110STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.87526056
111ESR1_20079471_ChIP-ChIP_T-47D_Human0.87334350
112NFIB_24661679_ChIP-Seq_LUNG_Mouse0.87163153
113SMC4_20622854_ChIP-Seq_HELA_Human0.86240339
114CTBP2_25329375_ChIP-Seq_LNCAP_Human0.86230334
115GATA1_19941826_ChIP-Seq_K562_Human0.85666659
116SMAD3_21741376_ChIP-Seq_ESCs_Human0.85552290
117PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.85215971
118PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.85122422
119TP53_16413492_ChIP-PET_HCT116_Human0.84240146
120CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.83866791
121STAT3_23295773_ChIP-Seq_U87_Human0.83453844

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.95553233
2MP0003635_abnormal_synaptic_transmissio3.42856443
3MP0009780_abnormal_chondrocyte_physiolo3.18335053
4MP0004270_analgesia2.94524998
5MP0000569_abnormal_digit_pigmentation2.94214182
6MP0002063_abnormal_learning/memory/cond2.59757145
7MP0002909_abnormal_adrenal_gland2.56408541
8MP0003880_abnormal_central_pattern2.44562457
9MP0008961_abnormal_basal_metabolism2.38842838
10MP0005423_abnormal_somatic_nervous2.38628928
11MP0009745_abnormal_behavioral_response2.32105385
12MP0005409_darkened_coat_color2.26352238
13MP0002064_seizures2.26279280
14MP0009046_muscle_twitch2.10797838
15MP0004858_abnormal_nervous_system1.99509326
16MP0008569_lethality_at_weaning1.98152796
17MP0002009_preneoplasia1.94705744
18MP0002572_abnormal_emotion/affect_behav1.89684352
19MP0001486_abnormal_startle_reflex1.85558385
20MP0003329_amyloid_beta_deposits1.84950442
21MP0004885_abnormal_endolymph1.83191304
22MP0002734_abnormal_mechanical_nocicepti1.79112141
23MP0000778_abnormal_nervous_system1.76668696
24MP0004811_abnormal_neuron_physiology1.71878891
25MP0003705_abnormal_hypodermis_morpholog1.66598506
26MP0002272_abnormal_nervous_system1.60901718
27MP0003283_abnormal_digestive_organ1.60132232
28MP0003787_abnormal_imprinting1.59571280
29MP0004130_abnormal_muscle_cell1.58861074
30MP0002877_abnormal_melanocyte_morpholog1.57540842
31MP0000751_myopathy1.57267579
32MP0001501_abnormal_sleep_pattern1.55228739
33MP0001968_abnormal_touch/_nociception1.55171460
34MP0000013_abnormal_adipose_tissue1.52443231
35MP0009278_abnormal_bone_marrow1.50417906
36MP0002249_abnormal_larynx_morphology1.50027860
37MP0000955_abnormal_spinal_cord1.47216957
38MP0002184_abnormal_innervation1.45526245
39MP0002557_abnormal_social/conspecific_i1.41373957
40MP0002822_catalepsy1.41032041
41MP0005503_abnormal_tendon_morphology1.40986401
42MP0002067_abnormal_sensory_capabilities1.37889957
43MP0002733_abnormal_thermal_nociception1.37679446
44MP0001440_abnormal_grooming_behavior1.34973776
45MP0010234_abnormal_vibrissa_follicle1.34272126
46MP0003633_abnormal_nervous_system1.33942652
47MP0003300_gastrointestinal_ulcer1.33260900
48MP0000003_abnormal_adipose_tissue1.33179086
49MP0002882_abnormal_neuron_morphology1.26756981
50MP0005187_abnormal_penis_morphology1.26326885
51MP0003122_maternal_imprinting1.25590701
52MP0003045_fibrosis1.24321825
53MP0001970_abnormal_pain_threshold1.23893927
54MP0003879_abnormal_hair_cell1.22565507
55MP0003172_abnormal_lysosome_physiology1.22253871
56MP0001958_emphysema1.20960931
57MP0005076_abnormal_cell_differentiation1.19568282
58MP0004924_abnormal_behavior1.18600687
59MP0005386_behavior/neurological_phenoty1.18600687
60MP0002837_dystrophic_cardiac_calcinosis1.18594732
61MP0003690_abnormal_glial_cell1.18338486
62MP0005645_abnormal_hypothalamus_physiol1.15947815
63MP0002396_abnormal_hematopoietic_system1.15703444
64MP0003115_abnormal_respiratory_system1.15364731
65MP0001502_abnormal_circadian_rhythm1.11804141
66MP0002066_abnormal_motor_capabilities/c1.11369849
67MP0005375_adipose_tissue_phenotype1.09765626
68MP0003091_abnormal_cell_migration1.08799651
69MP0001299_abnormal_eye_distance/1.08387909
70MP0002152_abnormal_brain_morphology1.08338401
71MP0004233_abnormal_muscle_weight1.05709184
72MP0002090_abnormal_vision1.04723419
73MP0003303_peritoneal_inflammation1.04618719
74MP0003632_abnormal_nervous_system1.02074570
75MP0000733_abnormal_muscle_development1.01299179
76MP0003385_abnormal_body_wall1.00814304
77MP0005670_abnormal_white_adipose0.99564377
78MP0004510_myositis0.99251589
79MP0002069_abnormal_eating/drinking_beha0.99118013
80MP0001943_abnormal_respiration0.98261834
81MP0000604_amyloidosis0.97284847
82MP0002234_abnormal_pharynx_morphology0.96317951
83MP0010769_abnormal_survival0.94642686
84MP0005551_abnormal_eye_electrophysiolog0.94173610
85MP0003631_nervous_system_phenotype0.94104036
86MP0002735_abnormal_chemical_nociception0.93077881
87MP0003075_altered_response_to0.92739290
88MP0002082_postnatal_lethality0.92707690
89MP0010770_preweaning_lethality0.92707690
90MP0005535_abnormal_body_temperature0.92332222
91MP0002089_abnormal_postnatal_growth/wei0.92021880
92MP0002108_abnormal_muscle_morphology0.91745917
93MP0004145_abnormal_muscle_electrophysio0.91101577
94MP0004085_abnormal_heartbeat0.90932325
95MP0001849_ear_inflammation0.90829493
96MP0005666_abnormal_adipose_tissue0.90813976
97MP0010768_mortality/aging0.90767569
98MP0003634_abnormal_glial_cell0.90666554
99MP0005167_abnormal_blood-brain_barrier0.90142482
100MP0001984_abnormal_olfaction0.90117087
101MP0003942_abnormal_urinary_system0.89805972
102MP0002081_perinatal_lethality0.87288868
103MP0004043_abnormal_pH_regulation0.86562432
104MP0004185_abnormal_adipocyte_glucose0.85828195
105MP0002116_abnormal_craniofacial_bone0.85269595
106MP0001177_atelectasis0.84850773
107MP0000534_abnormal_ureter_morphology0.84044248
108MP0005646_abnormal_pituitary_gland0.83707550
109MP0003948_abnormal_gas_homeostasis0.82980583
110MP0005623_abnormal_meninges_morphology0.82707536
111MP0003183_abnormal_peptide_metabolism0.82533133
112MP0002736_abnormal_nociception_after0.80806309
113MP0003137_abnormal_impulse_conducting0.80383046
114MP0002229_neurodegeneration0.79879336
115MP0000537_abnormal_urethra_morphology0.78330992
116MP0000747_muscle_weakness0.77478702
117MP0000566_synostosis0.77198369
118MP0005171_absent_coat_pigmentation0.75245134
119MP0002932_abnormal_joint_morphology0.73984778
120MP0002114_abnormal_axial_skeleton0.73793701
121MP0000428_abnormal_craniofacial_morphol0.73622261
122MP0004808_abnormal_hematopoietic_stem0.73069356
123MP0008874_decreased_physiological_sensi0.72731871
124MP0003938_abnormal_ear_development0.71985092
125MP0002078_abnormal_glucose_homeostasis0.71981123
126MP0002970_abnormal_white_adipose0.71746536
127MP0002752_abnormal_somatic_nervous0.71731949
128MP0003252_abnormal_bile_duct0.71182142
129MP0004087_abnormal_muscle_fiber0.70409035
130MP0005448_abnormal_energy_balance0.70151680
131MP0010329_abnormal_lipoprotein_level0.70058062
132MP0001348_abnormal_lacrimal_gland0.68945326
133MP0000631_abnormal_neuroendocrine_gland0.68479018
134MP0001944_abnormal_pancreas_morphology0.67416679
135MP0003861_abnormal_nervous_system0.62800256
136MP0002896_abnormal_bone_mineralization0.61956025

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)3.72932628
2Visual hallucinations (HP:0002367)3.41766467
3Hyperacusis (HP:0010780)3.38737217
4Supranuclear gaze palsy (HP:0000605)3.38095911
5Focal seizures (HP:0007359)3.33194766
6Action tremor (HP:0002345)3.30450618
7Insomnia (HP:0100785)3.21416794
8Macroorchidism (HP:0000053)3.09899412
9Genetic anticipation (HP:0003743)2.98642451
10Focal motor seizures (HP:0011153)2.98216826
11Elfin facies (HP:0004428)2.98010762
12Abnormality of the lower motor neuron (HP:0002366)2.96379440
13Abnormality of the fingertips (HP:0001211)2.95639490
14Progressive cerebellar ataxia (HP:0002073)2.83524546
15Papilledema (HP:0001085)2.73214296
16Hemiplegia (HP:0002301)2.71858279
17Ankle clonus (HP:0011448)2.62395881
18Broad face (HP:0000283)2.59829226
19Renovascular hypertension (HP:0100817)2.58516805
20Dysmetric saccades (HP:0000641)2.58512101
21Depression (HP:0000716)2.57941227
22Abnormal social behavior (HP:0012433)2.53446280
23Impaired social interactions (HP:0000735)2.53446280
24Abnormality of the ischium (HP:0003174)2.48661445
25Pointed chin (HP:0000307)2.41989933
26Overriding aorta (HP:0002623)2.39575434
27Heterotopia (HP:0002282)2.39112830
28Postural instability (HP:0002172)2.37378395
29Epileptic encephalopathy (HP:0200134)2.34620589
30Poor eye contact (HP:0000817)2.33842977
31Urinary bladder sphincter dysfunction (HP:0002839)2.33049417
32Shallow orbits (HP:0000586)2.30739109
33Agitation (HP:0000713)2.30182544
34Hypoplastic ischia (HP:0003175)2.29542254
35Long eyelashes (HP:0000527)2.28637380
36Impaired vibration sensation in the lower limbs (HP:0002166)2.27821905
37Enlarged penis (HP:0000040)2.27022870
38Neoplasm of the heart (HP:0100544)2.27001306
39Mild short stature (HP:0003502)2.25551975
40Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.25038451
41Vertebral arch anomaly (HP:0008438)2.23369102
42Cerebral aneurysm (HP:0004944)2.23362845
43Cerebral inclusion bodies (HP:0100314)2.22269574
44Bronchomalacia (HP:0002780)2.22158563
45Broad metatarsal (HP:0001783)2.21047748
46Mutism (HP:0002300)2.18297599
47Truncal ataxia (HP:0002078)2.17653796
48Urethral obstruction (HP:0000796)2.17569525
49Dysdiadochokinesis (HP:0002075)2.17522372
50Urinary urgency (HP:0000012)2.15671701
51Torticollis (HP:0000473)2.15035197
52Drooling (HP:0002307)2.13781125
53Excessive salivation (HP:0003781)2.13781125
54Ventricular fibrillation (HP:0001663)2.13703930
55Protrusio acetabuli (HP:0003179)2.13497460
56Morphological abnormality of the middle ear (HP:0008609)2.12395534
57Abnormality of the aortic arch (HP:0012303)2.11383980
58Megalencephaly (HP:0001355)2.11227226
59Absence seizures (HP:0002121)2.07961156
60Neonatal short-limb short stature (HP:0008921)2.06384164
61Megalocornea (HP:0000485)2.05401066
62Renal duplication (HP:0000075)2.03508137
63Impaired smooth pursuit (HP:0007772)2.02114087
64Truncal obesity (HP:0001956)2.01902678
65Insidious onset (HP:0003587)2.01766719
66Termporal pattern (HP:0011008)2.01766719
67Intention tremor (HP:0002080)2.01033639
68Lymphangioma (HP:0100764)2.00925330
69Generalized tonic-clonic seizures (HP:0002069)2.00598035
70Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.99397103
71Neurofibrillary tangles (HP:0002185)1.99350849
72Wide anterior fontanel (HP:0000260)1.98509033
73Precocious puberty (HP:0000826)1.97882234
74Dysmetria (HP:0001310)1.97433163
75Turricephaly (HP:0000262)1.96762888
76Distal upper limb amyotrophy (HP:0007149)1.96377243
77Upper limb amyotrophy (HP:0009129)1.96377243
78Abnormal eating behavior (HP:0100738)1.96001678
79Bundle branch block (HP:0011710)1.95400280
80Hemiparesis (HP:0001269)1.95326803
81Hammertoe (HP:0001765)1.95091246
82Obsessive-compulsive behavior (HP:0000722)1.94162091
83Flat cornea (HP:0007720)1.93637997
84Peripheral hypomyelination (HP:0007182)1.92985803
85Broad-based gait (HP:0002136)1.92153773
86Protruding tongue (HP:0010808)1.88095713
87Anxiety (HP:0000739)1.87937685
88Spastic gait (HP:0002064)1.87374265
89Bowel diverticulosis (HP:0005222)1.85623698
90Atonic seizures (HP:0010819)1.85505769
91Abnormality of ocular smooth pursuit (HP:0000617)1.85409109
92Spina bifida occulta (HP:0003298)1.84681226
93Tented upper lip vermilion (HP:0010804)1.84492241
94Abnormality of chromosome segregation (HP:0002916)1.84432478
95Febrile seizures (HP:0002373)1.83934086
96Mitral valve prolapse (HP:0001634)1.83920313
97Trigonocephaly (HP:0000243)1.83887214
98Genu recurvatum (HP:0002816)1.83485942
99Germ cell neoplasia (HP:0100728)1.82816165
100Hand muscle atrophy (HP:0009130)1.81886602
101Stereotypic behavior (HP:0000733)1.81717143
102Apathy (HP:0000741)1.81570599
103High anterior hairline (HP:0009890)1.81404400
104Patellar dislocation (HP:0002999)1.81150594
105Neuronal loss in central nervous system (HP:0002529)1.80607987
106Hyperventilation (HP:0002883)1.80534420
107Focal dystonia (HP:0004373)1.79856304
108Hypercortisolism (HP:0001578)1.79590306
109Sleep apnea (HP:0010535)1.78793724
110Prolonged QT interval (HP:0001657)1.78559102
111Bladder diverticulum (HP:0000015)1.77860893
112Amyotrophic lateral sclerosis (HP:0007354)1.77596816
113Long toe (HP:0010511)1.77386043
114Difficulty running (HP:0009046)1.76764429
115Lower limb muscle weakness (HP:0007340)1.76740747
116Inappropriate behavior (HP:0000719)1.76548145
117Gaze-evoked nystagmus (HP:0000640)1.76366052
118Tracheomalacia (HP:0002779)1.74339661
119Obstructive sleep apnea (HP:0002870)1.74019567
120Hypoventilation (HP:0002791)1.73209291
121Buphthalmos (HP:0000557)1.72880219
122Diplopia (HP:0000651)1.72490544
123Abnormality of binocular vision (HP:0011514)1.72490544
124Abnormality of the radial head (HP:0003995)1.72092997
125Thick eyebrow (HP:0000574)1.72000114
126Dialeptic seizures (HP:0011146)1.71390109
127Sacral dimple (HP:0000960)1.71219037
128Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.71012634
129Aqueductal stenosis (HP:0002410)1.70444183
130EEG with generalized epileptiform discharges (HP:0011198)1.70428266
131Ankyloglossia (HP:0010296)1.70133298
132Narrow palate (HP:0000189)1.69761932
133Biconcave vertebral bodies (HP:0004586)1.69546245
134Hypsarrhythmia (HP:0002521)1.69263925
135Postural tremor (HP:0002174)1.69200263
136Central scotoma (HP:0000603)1.68615591
137Laryngomalacia (HP:0001601)1.67866796
138Lower limb amyotrophy (HP:0007210)1.67443832
139Increased nuchal translucency (HP:0010880)1.66320348
140Tapered finger (HP:0001182)1.66127334
141Dislocated radial head (HP:0003083)1.64931482
142Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.63669366
143Hypopigmentation of the fundus (HP:0007894)1.61501063
144Decreased motor nerve conduction velocity (HP:0003431)1.60616463
145Ulnar bowing (HP:0003031)1.60555452
146Vascular tortuosity (HP:0004948)1.60248402
147Open mouth (HP:0000194)1.60101930
148Arterial tortuosity (HP:0005116)1.59717818
149Smooth philtrum (HP:0000319)1.58939583
150Overgrowth (HP:0001548)1.57919005
151Atelectasis (HP:0100750)1.57108609
152Deeply set eye (HP:0000490)1.56937936
153Thin ribs (HP:0000883)1.55292964
154Broad palm (HP:0001169)1.55074192
155Hypoplasia of the iris (HP:0007676)1.54323269
156EMG: neuropathic changes (HP:0003445)1.53792724
157Attention deficit hyperactivity disorder (HP:0007018)1.53660004

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.61476025
2MARK13.28077753
3TRIB33.06081876
4MAP3K92.55800599
5NTRK32.53993173
6PRKD32.48392129
7BRD42.38342460
8SIK22.38288346
9CAMK1G2.26541801
10RIPK12.15058424
11PAK62.14645113
12DAPK22.06572657
13CAMKK12.04337102
14MAP3K42.00532955
15NTRK21.95977469
16CASK1.95034246
17MINK11.78531549
18EPHA41.76139437
19SIK11.74275403
20PKN21.73007018
21CAMK1D1.56037255
22NTRK11.50398077
23ICK1.47987429
24TYRO31.43540603
25TAOK11.42090797
26KSR21.40831359
27PRKCH1.40258086
28PDGFRA1.39744700
29STK381.36129916
30MAP3K101.32983406
31FGFR41.28666591
32PRPF4B1.27883678
33KSR11.23934865
34PTK61.23678546
35MAP2K41.23458687
36CDK51.21025190
37MAP3K131.20872393
38PHKG11.20156817
39PHKG21.20156817
40RET1.19257232
41EEF2K1.18075424
42MARK21.16653443
43LMTK21.13914046
44DMPK1.10233632
45FGFR21.10159893
46UHMK11.09586858
47SGK31.08142856
48ALK1.08077993
49MAP3K71.03916149
50CDC42BPA1.03534699
51TNK21.01514858
52EPHA30.99377230
53STK110.98755785
54ERN10.98219470
55PAK30.95885998
56MAP3K20.95043712
57SMG10.92771762
58INSRR0.89842100
59TNIK0.89467819
60WNK10.87849073
61DDR20.87196926
62FES0.85716968
63MAP2K70.81698068
64CAMK10.80591428
65MAPK130.79855401
66ERBB20.79358614
67MAP3K60.75995587
68SGK2230.72420989
69SGK4940.72420989
70CAMKK20.70680646
71RIPK40.68617320
72HIPK20.67560030
73SCYL20.67255326
74PDPK10.66995575
75PDGFRB0.66995320
76EPHB20.66469757
77CAMK40.66395370
78PDK10.66229260
79PRKCZ0.65342607
80BMX0.64689485
81RPS6KA20.63612943
82SGK20.62743785
83PRKD10.62175908
84MTOR0.61977221
85SIK30.61566519
86PNCK0.61380331
87FYN0.60888278
88PTK20.60054286
89PRKD20.59912756
90PRKCG0.59338765
91FGFR30.58946170
92* MAPK80.58669617
93CAMK2B0.58472446
94MAPK120.58071762
95CDK90.58049564
96LATS20.57942642
97SGK10.57250049
98* GSK3B0.56983573
99DAPK10.55838984
100MAPK110.55807563
101CDK150.55103688
102PRKAA10.54796339
103PTK2B0.54705564
104JAK10.54703525
105MAP2K20.54570372
106TTN0.53783153
107CDK180.53187440
108EPHB10.53105146
109ERBB30.52812518
110CSNK1G20.52529657
111* RPS6KA30.52392657
112DYRK1B0.50123414
113DYRK1A0.49617618
114ROCK10.49399085
115FER0.48587746
116NEK60.48040402
117CDK140.47679768
118MAP3K10.47520295
119CDK11A0.45779548
120MAPK100.45362254
121CDK20.45217030
122PAK20.44551632
123MAPK90.43743284
124ROCK20.43330907
125MET0.42298579
126MAPK140.40953337
127MAPK10.40406611
128NEK20.39952778
129* CDK10.39815144

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.31714018
2Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.99815120
3Synaptic vesicle cycle_Homo sapiens_hsa047211.92880792
4Circadian entrainment_Homo sapiens_hsa047131.92378698
5Nicotine addiction_Homo sapiens_hsa050331.88257441
6GABAergic synapse_Homo sapiens_hsa047271.87058929
7Olfactory transduction_Homo sapiens_hsa047401.76448265
8Glutamatergic synapse_Homo sapiens_hsa047241.73676568
9Long-term potentiation_Homo sapiens_hsa047201.72586552
10Aldosterone synthesis and secretion_Homo sapiens_hsa049251.72392297
11Type II diabetes mellitus_Homo sapiens_hsa049301.72075121
12Insulin secretion_Homo sapiens_hsa049111.71341054
13Morphine addiction_Homo sapiens_hsa050321.63616531
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.59468863
15Gastric acid secretion_Homo sapiens_hsa049711.56456793
16Notch signaling pathway_Homo sapiens_hsa043301.55809233
17Salivary secretion_Homo sapiens_hsa049701.55635465
18Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.51908445
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.49704264
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.48862372
21Amphetamine addiction_Homo sapiens_hsa050311.48197399
22Dopaminergic synapse_Homo sapiens_hsa047281.48126059
23Cholinergic synapse_Homo sapiens_hsa047251.47048266
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.42485667
25Renin secretion_Homo sapiens_hsa049241.36825295
26Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.31102102
27Cocaine addiction_Homo sapiens_hsa050301.28514879
28Oxytocin signaling pathway_Homo sapiens_hsa049211.26537758
29Glioma_Homo sapiens_hsa052141.24400777
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.22782956
31Estrogen signaling pathway_Homo sapiens_hsa049151.22523425
32Acute myeloid leukemia_Homo sapiens_hsa052211.20687903
33GnRH signaling pathway_Homo sapiens_hsa049121.14962483
34Dorso-ventral axis formation_Homo sapiens_hsa043201.09819048
35cAMP signaling pathway_Homo sapiens_hsa040241.09666452
36Gap junction_Homo sapiens_hsa045401.09621947
37Axon guidance_Homo sapiens_hsa043601.06988991
38Phosphatidylinositol signaling system_Homo sapiens_hsa040701.06529683
39Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.05162006
40cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03658210
41Long-term depression_Homo sapiens_hsa047301.02875439
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01954202
43Bile secretion_Homo sapiens_hsa049761.00442866
44mTOR signaling pathway_Homo sapiens_hsa041500.98072245
45Adherens junction_Homo sapiens_hsa045200.96029242
46Thyroid hormone signaling pathway_Homo sapiens_hsa049190.95571846
47Endometrial cancer_Homo sapiens_hsa052130.94848677
48Dilated cardiomyopathy_Homo sapiens_hsa054140.94353233
49Taste transduction_Homo sapiens_hsa047420.94344409
50Neurotrophin signaling pathway_Homo sapiens_hsa047220.93657207
51Calcium signaling pathway_Homo sapiens_hsa040200.93424816
52ErbB signaling pathway_Homo sapiens_hsa040120.92361856
53B cell receptor signaling pathway_Homo sapiens_hsa046620.92180136
54MicroRNAs in cancer_Homo sapiens_hsa052060.91386959
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.90929441
56Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90727171
57Pancreatic secretion_Homo sapiens_hsa049720.89886378
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.88548278
59Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.86375082
60Longevity regulating pathway - mammal_Homo sapiens_hsa042110.86053816
61Melanogenesis_Homo sapiens_hsa049160.85400601
62Lysine degradation_Homo sapiens_hsa003100.83715219
63Insulin resistance_Homo sapiens_hsa049310.83056261
64Thyroid hormone synthesis_Homo sapiens_hsa049180.82460778
65Glucagon signaling pathway_Homo sapiens_hsa049220.82182653
66Insulin signaling pathway_Homo sapiens_hsa049100.81942145
67Non-small cell lung cancer_Homo sapiens_hsa052230.81126433
68Prostate cancer_Homo sapiens_hsa052150.80608667
69VEGF signaling pathway_Homo sapiens_hsa043700.80472752
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.77381497
71mRNA surveillance pathway_Homo sapiens_hsa030150.75714943
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.74554904
73Circadian rhythm_Homo sapiens_hsa047100.74160889
74Thyroid cancer_Homo sapiens_hsa052160.72412234
75Choline metabolism in cancer_Homo sapiens_hsa052310.72379280
76Chronic myeloid leukemia_Homo sapiens_hsa052200.72183290
77Renal cell carcinoma_Homo sapiens_hsa052110.71656798
78T cell receptor signaling pathway_Homo sapiens_hsa046600.71648499
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71053303
80Serotonergic synapse_Homo sapiens_hsa047260.70756737
81Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.69088135
82FoxO signaling pathway_Homo sapiens_hsa040680.67782711
83Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.67588412
84Tight junction_Homo sapiens_hsa045300.67423714
85AMPK signaling pathway_Homo sapiens_hsa041520.67247852
86Fatty acid biosynthesis_Homo sapiens_hsa000610.66535901
87Arginine biosynthesis_Homo sapiens_hsa002200.65476254
88MAPK signaling pathway_Homo sapiens_hsa040100.64765425
89Endocytosis_Homo sapiens_hsa041440.63732430
90Adipocytokine signaling pathway_Homo sapiens_hsa049200.63265398
91Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.62796350
92Hippo signaling pathway_Homo sapiens_hsa043900.61899535
93Rap1 signaling pathway_Homo sapiens_hsa040150.61072889
94ECM-receptor interaction_Homo sapiens_hsa045120.58777379
95Proteoglycans in cancer_Homo sapiens_hsa052050.57420042
96Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.56139198
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.55660146
98Prolactin signaling pathway_Homo sapiens_hsa049170.55621813
99Central carbon metabolism in cancer_Homo sapiens_hsa052300.55070309
100Colorectal cancer_Homo sapiens_hsa052100.54358987
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.53992726
102Inositol phosphate metabolism_Homo sapiens_hsa005620.53468386
103Focal adhesion_Homo sapiens_hsa045100.52829521
104Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52817632
105ABC transporters_Homo sapiens_hsa020100.52673473
106Platelet activation_Homo sapiens_hsa046110.52452871
107Chemokine signaling pathway_Homo sapiens_hsa040620.49956754
108PPAR signaling pathway_Homo sapiens_hsa033200.47562532
109Pancreatic cancer_Homo sapiens_hsa052120.46292825
110Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45821846
111Phototransduction_Homo sapiens_hsa047440.44921343
112Butanoate metabolism_Homo sapiens_hsa006500.44376434
113Ras signaling pathway_Homo sapiens_hsa040140.44161831
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43680864
115Wnt signaling pathway_Homo sapiens_hsa043100.43368582
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43299347
117Prion diseases_Homo sapiens_hsa050200.41831355
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.41512844

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