SMIM13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)5.61448962
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.51009319
3sodium ion export (GO:0071436)5.50292990
4glutamate secretion (GO:0014047)5.47955620
5vocalization behavior (GO:0071625)5.46001796
6synaptic vesicle docking involved in exocytosis (GO:0016081)5.36669830
7regulation of synaptic vesicle exocytosis (GO:2000300)5.18741311
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.14441367
9neuronal action potential propagation (GO:0019227)5.14164688
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.06961990
11neuron cell-cell adhesion (GO:0007158)4.96776442
12synaptic vesicle maturation (GO:0016188)4.84813267
13regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.76747089
14protein localization to synapse (GO:0035418)4.73029764
15regulation of glutamate receptor signaling pathway (GO:1900449)4.70510107
16neurotransmitter-gated ion channel clustering (GO:0072578)4.62158924
17regulation of synaptic vesicle transport (GO:1902803)4.52956158
18presynaptic membrane assembly (GO:0097105)4.49464883
19locomotory exploration behavior (GO:0035641)4.48239786
20negative regulation of synaptic transmission, GABAergic (GO:0032229)4.41067236
21positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.40923716
22neurotransmitter secretion (GO:0007269)4.40415738
23ionotropic glutamate receptor signaling pathway (GO:0035235)4.33910535
24neuron-neuron synaptic transmission (GO:0007270)4.32048975
25positive regulation of dendritic spine morphogenesis (GO:0061003)4.23387908
26cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.21533065
27presynaptic membrane organization (GO:0097090)4.18909342
28gamma-aminobutyric acid signaling pathway (GO:0007214)4.16710060
29synaptic transmission, glutamatergic (GO:0035249)4.15343037
30gamma-aminobutyric acid transport (GO:0015812)4.05278806
31glutamate receptor signaling pathway (GO:0007215)3.97106453
32cell communication by electrical coupling (GO:0010644)3.96608290
33postsynaptic membrane organization (GO:0001941)3.93044010
34regulation of long-term neuronal synaptic plasticity (GO:0048169)3.91507918
35membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.88457171
36regulation of neuronal synaptic plasticity (GO:0048168)3.86420493
37long-term synaptic potentiation (GO:0060291)3.84147964
38positive regulation of dendritic spine development (GO:0060999)3.83278238
39regulation of excitatory postsynaptic membrane potential (GO:0060079)3.75258541
40exploration behavior (GO:0035640)3.64713447
41neurotransmitter transport (GO:0006836)3.63062454
42cellular sodium ion homeostasis (GO:0006883)3.58787578
43positive regulation of membrane potential (GO:0045838)3.58167848
44regulation of postsynaptic membrane potential (GO:0060078)3.56902513
45response to histamine (GO:0034776)3.56369002
46potassium ion homeostasis (GO:0055075)3.55483284
47regulation of neurotransmitter secretion (GO:0046928)3.54613559
48regulation of synaptic plasticity (GO:0048167)3.48704966
49regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.43966196
50positive regulation of neurotransmitter transport (GO:0051590)3.43837257
51establishment of mitochondrion localization (GO:0051654)3.42858051
52regulation of synaptic transmission, glutamatergic (GO:0051966)3.42007361
53cerebellar granule cell differentiation (GO:0021707)3.38916281
54negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.37322841
55neuromuscular process controlling balance (GO:0050885)3.36930112
56behavioral response to cocaine (GO:0048148)3.36375875
57neuron recognition (GO:0008038)3.36217007
58positive regulation of synapse maturation (GO:0090129)3.34556581
59long-term memory (GO:0007616)3.34436486
60regulation of neurotransmitter levels (GO:0001505)3.31644442
61regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.30830166
62regulation of neurotransmitter transport (GO:0051588)3.30290326
63establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.29937358
64mitochondrion transport along microtubule (GO:0047497)3.29937358
65potassium ion import (GO:0010107)3.28709681
66positive regulation of neurotransmitter secretion (GO:0001956)3.28238403
67mechanosensory behavior (GO:0007638)3.24978449
68startle response (GO:0001964)3.24919437
69ATP hydrolysis coupled proton transport (GO:0015991)3.24208886
70energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.24208886
71regulation of synapse structural plasticity (GO:0051823)3.23444953
72amino acid import (GO:0043090)3.22818040
73regulation of synapse maturation (GO:0090128)3.22687882
74synaptic vesicle endocytosis (GO:0048488)3.21971340
75transferrin transport (GO:0033572)3.21363061
76cerebellar Purkinje cell differentiation (GO:0021702)3.21284150
77proline transport (GO:0015824)3.20274705
78G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.19277330
79positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.18767200
80dendrite morphogenesis (GO:0048813)3.16679118
81neuromuscular process controlling posture (GO:0050884)3.15715218
82regulation of dendritic spine development (GO:0060998)3.14418096
83transmission of nerve impulse (GO:0019226)3.13697947
84regulation of female receptivity (GO:0045924)3.11353916
85L-amino acid import (GO:0043092)3.10861565
86positive regulation of synaptic transmission (GO:0050806)3.10439452
87cerebellar Purkinje cell layer development (GO:0021680)3.10184568
88membrane depolarization (GO:0051899)3.09407158
89regulation of synaptic transmission, GABAergic (GO:0032228)3.08809248
90regulation of voltage-gated calcium channel activity (GO:1901385)3.07194695
91G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.05975609
92negative regulation of dendrite morphogenesis (GO:0050774)3.05655395
93synaptic transmission (GO:0007268)3.05353501
94activation of protein kinase A activity (GO:0034199)3.03366241
95cell communication involved in cardiac conduction (GO:0086065)3.03002434
96positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.01491911
97negative regulation of neurotransmitter transport (GO:0051589)3.01177720
98positive regulation of synaptic transmission, GABAergic (GO:0032230)3.01040450
99regulation of vesicle fusion (GO:0031338)3.00983081
100membrane depolarization during action potential (GO:0086010)3.00929933
101neuronal ion channel clustering (GO:0045161)3.00122833
102learning (GO:0007612)3.00046998
103regulation of synaptic transmission (GO:0050804)2.99187727
104regulation of cAMP-dependent protein kinase activity (GO:2000479)2.99033824
105striatum development (GO:0021756)2.98944171
106long term synaptic depression (GO:0060292)2.98711983
107female mating behavior (GO:0060180)2.98557146
108trivalent inorganic cation transport (GO:0072512)2.98127813
109ferric iron transport (GO:0015682)2.98127813
110central nervous system projection neuron axonogenesis (GO:0021952)2.97592290
111mating behavior (GO:0007617)2.96819850
112regulation of dendritic spine morphogenesis (GO:0061001)2.96051429
113regulation of glutamate secretion (GO:0014048)2.95817446
114auditory behavior (GO:0031223)2.95543326
115positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.94785704
116positive regulation of synapse assembly (GO:0051965)2.92425586
117dendritic spine morphogenesis (GO:0060997)2.92395962
118cellular potassium ion homeostasis (GO:0030007)2.91518481
119central nervous system myelination (GO:0022010)2.90339291
120axon ensheathment in central nervous system (GO:0032291)2.90339291
121cytoskeletal anchoring at plasma membrane (GO:0007016)2.89871151
122axonal fasciculation (GO:0007413)2.89757867
123calcium ion-dependent exocytosis (GO:0017156)2.88538171
124adult walking behavior (GO:0007628)2.86645475
125membrane hyperpolarization (GO:0060081)2.86539055
126synapse assembly (GO:0007416)2.85656438
127cell migration in hindbrain (GO:0021535)2.85227929
128layer formation in cerebral cortex (GO:0021819)2.84233631
129behavioral defense response (GO:0002209)2.83835546
130negative regulation of inclusion body assembly (GO:0090084)2.82615172
131negative regulation of dendrite development (GO:2000171)2.79947169
132neuromuscular process (GO:0050905)2.71073384
133suckling behavior (GO:0001967)2.70614266
134regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.68404906
135regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.65349096
136membrane assembly (GO:0071709)2.64648329
137detection of calcium ion (GO:0005513)2.64532396
138regulation of dendrite morphogenesis (GO:0048814)2.63010133
139organelle transport along microtubule (GO:0072384)2.61817047
140regulation of synapse assembly (GO:0051963)2.60180578

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.32484736
2GBX2_23144817_ChIP-Seq_PC3_Human4.50689592
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.05436913
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.87945835
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.80681142
6RBPJ_22232070_ChIP-Seq_NCS_Mouse2.77287284
7TAF15_26573619_Chip-Seq_HEK293_Human2.72396066
8REST_21632747_ChIP-Seq_MESCs_Mouse2.63207245
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.47233407
10TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.42174714
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.37769743
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.37769743
13RARB_27405468_Chip-Seq_BRAIN_Mouse2.32153317
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.31009807
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.30971477
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.29658939
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.29573742
18JARID2_20075857_ChIP-Seq_MESCs_Mouse2.29538827
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.28014582
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18136526
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.16517305
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.14456260
23EED_16625203_ChIP-ChIP_MESCs_Mouse2.07564064
24ZFP57_27257070_Chip-Seq_ESCs_Mouse2.04720807
25CTBP1_25329375_ChIP-Seq_LNCAP_Human2.03829752
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.03326955
27DROSHA_22980978_ChIP-Seq_HELA_Human2.02140376
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.00758404
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.00208956
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.94528718
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.91396562
32SMAD4_21799915_ChIP-Seq_A2780_Human1.89415439
33EZH2_27294783_Chip-Seq_ESCs_Mouse1.88670248
34RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.86818184
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.83229639
36EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.82617654
37P300_19829295_ChIP-Seq_ESCs_Human1.79425778
38AR_21572438_ChIP-Seq_LNCaP_Human1.79390960
39CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.76593042
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.74969089
41WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.74617230
42SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.74218492
43GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60777437
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.59223565
45RING1B_27294783_Chip-Seq_NPCs_Mouse1.58437998
46MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58092859
47VDR_22108803_ChIP-Seq_LS180_Human1.56997254
48FUS_26573619_Chip-Seq_HEK293_Human1.53368927
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52497417
50SMAD3_21741376_ChIP-Seq_EPCs_Human1.51520658
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51373626
52IKZF1_21737484_ChIP-ChIP_HCT116_Human1.50477737
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.50049623
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.46521747
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45088418
56AR_25329375_ChIP-Seq_VCAP_Human1.44060965
57SOX2_21211035_ChIP-Seq_LN229_Gbm1.41021551
58KDM2B_26808549_Chip-Seq_K562_Human1.40274036
59STAT3_23295773_ChIP-Seq_U87_Human1.39646667
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.36690658
61BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36688960
62ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.34693155
63ZFP281_18757296_ChIP-ChIP_E14_Mouse1.34003095
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.32549665
65CBX2_27304074_Chip-Seq_ESCs_Mouse1.32291397
66GATA1_26923725_Chip-Seq_HPCs_Mouse1.31311655
67TRIM28_21343339_ChIP-Seq_HEK293_Human1.29768361
68FOXM1_23109430_ChIP-Seq_U2OS_Human1.29678632
69ZFP281_27345836_Chip-Seq_ESCs_Mouse1.29462653
70WT1_19549856_ChIP-ChIP_CCG9911_Human1.28850305
71THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.27182408
72AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26576288
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.26184705
74TCF4_23295773_ChIP-Seq_U87_Human1.25165455
75ZNF274_21170338_ChIP-Seq_K562_Hela1.24358546
76ER_23166858_ChIP-Seq_MCF-7_Human1.24317901
77DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.23053903
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22804077
79BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.21496596
80RNF2_27304074_Chip-Seq_NSC_Mouse1.20246150
81PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.18301984
82EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.18184735
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.18062096
84P53_22127205_ChIP-Seq_FIBROBLAST_Human1.18019266
85EP300_21415370_ChIP-Seq_HL-1_Mouse1.17032783
86NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.16638317
87TP53_20018659_ChIP-ChIP_R1E_Mouse1.16310699
88PRDM14_20953172_ChIP-Seq_ESCs_Human1.14729079
89CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14512205
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.14351400
91RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14216435
92ERG_21242973_ChIP-ChIP_JURKAT_Human1.13621320
93JUN_21703547_ChIP-Seq_K562_Human1.11992960
94* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11929990
95NANOG_18555785_Chip-Seq_ESCs_Mouse1.11756766
96RUNX2_22187159_ChIP-Seq_PCA_Human1.11009694
97CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08773841
98TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08686222
99RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.08107620
100AR_19668381_ChIP-Seq_PC3_Human1.07968188
101AHR_22903824_ChIP-Seq_MCF-7_Human1.06435767
102POU3F1_26484290_ChIP-Seq_ESCss_Mouse1.04543470
103IGF1R_20145208_ChIP-Seq_DFB_Human1.04435065
104TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.03720550
105MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03248042
106TP53_18474530_ChIP-ChIP_U2OS_Human1.02409232
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01848521
108OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.01491353
109HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.00244011
110FLI1_27457419_Chip-Seq_LIVER_Mouse1.00045615
111RING1B_27294783_Chip-Seq_ESCs_Mouse0.98936198
112E2F1_18555785_Chip-Seq_ESCs_Mouse0.98457137
113ZNF217_24962896_ChIP-Seq_MCF-7_Human0.98429943
114TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.97779063
115LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97680438
116AR_21909140_ChIP-Seq_LNCAP_Human0.97352865
117YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97220833
118SALL1_21062744_ChIP-ChIP_HESCs_Human0.97115087
119CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96476068
120CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96312360
121NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95977393
122KDM2B_26808549_Chip-Seq_REH_Human0.95336819
123CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94236162
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94202300
125POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94202300
126P53_22387025_ChIP-Seq_ESCs_Mouse0.94013856
127TET1_21490601_ChIP-Seq_MESCs_Mouse0.93327259
128CLOCK_20551151_ChIP-Seq_293T_Human0.93104428
129CMYC_18555785_Chip-Seq_ESCs_Mouse0.92684463
130SOX9_26525672_Chip-Seq_HEART_Mouse0.92651811
131MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92218729
132ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91785681
133SMAD3_21741376_ChIP-Seq_ESCs_Human0.91748178
134EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91728900
135REST_19997604_ChIP-ChIP_NEURONS_Mouse0.91366087
136TP53_16413492_ChIP-PET_HCT116_Human0.90970330
137BCAT_22108803_ChIP-Seq_LS180_Human0.90453359
138MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89421181

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.73470122
2MP0003880_abnormal_central_pattern5.26206681
3MP0003635_abnormal_synaptic_transmissio4.03829296
4MP0004270_analgesia3.80923943
5MP0009745_abnormal_behavioral_response3.53905280
6MP0009046_muscle_twitch3.52785128
7MP0002064_seizures3.39076360
8MP0002063_abnormal_learning/memory/cond3.28315237
9MP0001968_abnormal_touch/_nociception3.23450465
10MP0002572_abnormal_emotion/affect_behav2.87550141
11MP0002272_abnormal_nervous_system2.83898239
12MP0002736_abnormal_nociception_after2.76375656
13MP0002734_abnormal_mechanical_nocicepti2.67451277
14MP0002822_catalepsy2.54594360
15MP0001486_abnormal_startle_reflex2.53613676
16MP0001501_abnormal_sleep_pattern2.36532424
17MP0002735_abnormal_chemical_nociception2.35625118
18MP0001440_abnormal_grooming_behavior2.18452395
19MP0005423_abnormal_somatic_nervous2.17770831
20MP0009780_abnormal_chondrocyte_physiolo2.16055918
21MP0002067_abnormal_sensory_capabilities2.15283659
22MP0003123_paternal_imprinting1.98659123
23MP0001970_abnormal_pain_threshold1.92076164
24MP0005646_abnormal_pituitary_gland1.91375844
25MP0002733_abnormal_thermal_nociception1.86190201
26MP0008569_lethality_at_weaning1.81704134
27MP0005386_behavior/neurological_phenoty1.80109399
28MP0004924_abnormal_behavior1.80109399
29MP0001529_abnormal_vocalization1.76597559
30MP0003329_amyloid_beta_deposits1.75067445
31MP0005623_abnormal_meninges_morphology1.73199488
32MP0003879_abnormal_hair_cell1.70293765
33MP0003787_abnormal_imprinting1.67068955
34MP0001984_abnormal_olfaction1.65560378
35MP0006276_abnormal_autonomic_nervous1.61194188
36MP0002184_abnormal_innervation1.59811758
37MP0002557_abnormal_social/conspecific_i1.57863727
38MP0004142_abnormal_muscle_tone1.56820257
39MP0004811_abnormal_neuron_physiology1.56075597
40MP0000778_abnormal_nervous_system1.55360901
41MP0001905_abnormal_dopamine_level1.50903479
42MP0002837_dystrophic_cardiac_calcinosis1.49110247
43MP0002066_abnormal_motor_capabilities/c1.43222250
44MP0002882_abnormal_neuron_morphology1.37250426
45MP0000955_abnormal_spinal_cord1.36796543
46MP0005551_abnormal_eye_electrophysiolog1.36538396
47MP0001188_hyperpigmentation1.33232025
48MP0002909_abnormal_adrenal_gland1.32849215
49MP0003633_abnormal_nervous_system1.31325379
50MP0001299_abnormal_eye_distance/1.24046314
51MP0003122_maternal_imprinting1.23586055
52MP0005187_abnormal_penis_morphology1.21935142
53MP0001502_abnormal_circadian_rhythm1.20711615
54MP0000751_myopathy1.20027841
55MP0002877_abnormal_melanocyte_morpholog1.19507950
56MP0002876_abnormal_thyroid_physiology1.18905470
57MP0004885_abnormal_endolymph1.18423864
58MP0002229_neurodegeneration1.16021681
59MP0003631_nervous_system_phenotype1.15622588
60MP0004858_abnormal_nervous_system1.13737087
61MP0005409_darkened_coat_color1.05977449
62MP0004145_abnormal_muscle_electrophysio1.03133849
63MP0003705_abnormal_hypodermis_morpholog1.03115519
64MP0000537_abnormal_urethra_morphology1.02922736
65MP0004742_abnormal_vestibular_system1.02133140
66MP0005645_abnormal_hypothalamus_physiol1.01033041
67MP0001348_abnormal_lacrimal_gland1.00571742
68MP0000013_abnormal_adipose_tissue0.99380491
69MP0000920_abnormal_myelination0.98909624
70MP0000569_abnormal_digit_pigmentation0.98130617
71MP0002638_abnormal_pupillary_reflex0.97189776
72MP0008872_abnormal_physiological_respon0.96517025
73MP0002152_abnormal_brain_morphology0.96437642
74MP0010386_abnormal_urinary_bladder0.96231206
75MP0003646_muscle_fatigue0.95028060
76MP0004484_altered_response_of0.93646375
77MP0001963_abnormal_hearing_physiology0.93498571
78MP0008874_decreased_physiological_sensi0.93381036
79MP0000534_abnormal_ureter_morphology0.93352946
80MP0001986_abnormal_taste_sensitivity0.92877670
81MP0003121_genomic_imprinting0.92279238
82MP0004215_abnormal_myocardial_fiber0.90512037
83MP0003861_abnormal_nervous_system0.90456470
84MP0004233_abnormal_muscle_weight0.88761093
85MP0002069_abnormal_eating/drinking_beha0.87475228
86MP0005535_abnormal_body_temperature0.87207201
87MP0003385_abnormal_body_wall0.86549485
88MP0004085_abnormal_heartbeat0.86322118
89MP0000579_abnormal_nail_morphology0.85029205
90MP0001346_abnormal_lacrimal_gland0.84772689
91MP0003942_abnormal_urinary_system0.84420113
92MP0004147_increased_porphyrin_level0.83828627
93MP0003632_abnormal_nervous_system0.83402195
94MP0005171_absent_coat_pigmentation0.83245132
95MP0004043_abnormal_pH_regulation0.80724687
96MP0003634_abnormal_glial_cell0.80412574
97MP0002081_perinatal_lethality0.79774854
98MP0000604_amyloidosis0.79013025
99MP0001177_atelectasis0.78055333
100MP0003690_abnormal_glial_cell0.77571313
101MP0002752_abnormal_somatic_nervous0.76889574
102MP0009672_abnormal_birth_weight0.76063444
103MP0002234_abnormal_pharynx_morphology0.71869419
104MP0010769_abnormal_survival0.70747952
105MP0003890_abnormal_embryonic-extraembry0.70698510
106MP0002090_abnormal_vision0.70206522
107MP0000747_muscle_weakness0.68163206
108MP0010768_mortality/aging0.68123253
109MP0004036_abnormal_muscle_relaxation0.67808846
110MP0001664_abnormal_digestion0.66810255
111MP0002160_abnormal_reproductive_system0.66469738
112MP0000631_abnormal_neuroendocrine_gland0.66420996
113MP0008877_abnormal_DNA_methylation0.65824947
114MP0005257_abnormal_intraocular_pressure0.65770681
115MP0001485_abnormal_pinna_reflex0.65329416
116MP0005499_abnormal_olfactory_system0.64978499
117MP0005394_taste/olfaction_phenotype0.64978499
118MP0005410_abnormal_fertilization0.63262989
119MP0001340_abnormal_eyelid_morphology0.62066541
120MP0000428_abnormal_craniofacial_morphol0.58939261
121MP0004130_abnormal_muscle_cell0.56263009
122MP0006035_abnormal_mitochondrial_morpho0.56155741
123MP0001943_abnormal_respiration0.55361423
124MP0009250_abnormal_appendicular_skeleto0.54583703
125MP0004087_abnormal_muscle_fiber0.54429559
126MP0003183_abnormal_peptide_metabolism0.50847467
127MP0005620_abnormal_muscle_contractility0.50773173
128MP0000026_abnormal_inner_ear0.50029417
129MP0003137_abnormal_impulse_conducting0.49936805
130MP0003956_abnormal_body_size0.49444091
131MP0002082_postnatal_lethality0.49158623
132MP0010770_preweaning_lethality0.49158623

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.64424245
2Atonic seizures (HP:0010819)6.06702940
3Epileptic encephalopathy (HP:0200134)5.87298293
4Myokymia (HP:0002411)5.66593533
5Focal seizures (HP:0007359)5.62155715
6Febrile seizures (HP:0002373)5.24431846
7Hyperventilation (HP:0002883)4.78746246
8Absence seizures (HP:0002121)4.72892064
9Dialeptic seizures (HP:0011146)4.35764830
10Visual hallucinations (HP:0002367)4.32358217
11Progressive cerebellar ataxia (HP:0002073)4.09476859
12Generalized tonic-clonic seizures (HP:0002069)3.95316437
13Broad-based gait (HP:0002136)3.68851044
14Gaze-evoked nystagmus (HP:0000640)3.42328967
15Pheochromocytoma (HP:0002666)3.38458895
16Impaired vibration sensation in the lower limbs (HP:0002166)3.24844741
17Poor eye contact (HP:0000817)3.24645478
18Neuroendocrine neoplasm (HP:0100634)3.04577440
19Dysdiadochokinesis (HP:0002075)3.01465425
20Abnormal social behavior (HP:0012433)2.98643657
21Impaired social interactions (HP:0000735)2.98643657
22Truncal ataxia (HP:0002078)2.89695536
23Urinary bladder sphincter dysfunction (HP:0002839)2.89641045
24Action tremor (HP:0002345)2.88730552
25Dysmetria (HP:0001310)2.84665127
26Abnormal eating behavior (HP:0100738)2.84125630
27Termporal pattern (HP:0011008)2.82161148
28Insidious onset (HP:0003587)2.82161148
29Ankle clonus (HP:0011448)2.81508900
30Epileptiform EEG discharges (HP:0011182)2.80683247
31Progressive inability to walk (HP:0002505)2.72300867
32Scanning speech (HP:0002168)2.71374879
33Anxiety (HP:0000739)2.66979925
34Gait imbalance (HP:0002141)2.66423766
35Supranuclear gaze palsy (HP:0000605)2.63839586
36Abnormality of binocular vision (HP:0011514)2.61292620
37Diplopia (HP:0000651)2.61292620
38Depression (HP:0000716)2.61208142
39Abnormality of the corticospinal tract (HP:0002492)2.60198141
40Inability to walk (HP:0002540)2.59093345
41Abnormal hair whorl (HP:0010721)2.58776101
42Drooling (HP:0002307)2.58609174
43Excessive salivation (HP:0003781)2.58609174
44Amblyopia (HP:0000646)2.58603111
45EEG with generalized epileptiform discharges (HP:0011198)2.54899238
46Tetraplegia (HP:0002445)2.54371091
47Insomnia (HP:0100785)2.53204412
48Degeneration of the lateral corticospinal tracts (HP:0002314)2.51573570
49Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.51573570
50Urinary urgency (HP:0000012)2.47755412
51Spastic gait (HP:0002064)2.47711050
52Fetal akinesia sequence (HP:0001989)2.44534853
53Hypsarrhythmia (HP:0002521)2.41963864
54Dysmetric saccades (HP:0000641)2.41430912
55Impaired vibratory sensation (HP:0002495)2.38409847
56Congenital primary aphakia (HP:0007707)2.37431120
57Obstructive sleep apnea (HP:0002870)2.37109210
58Generalized myoclonic seizures (HP:0002123)2.36823516
59Absent speech (HP:0001344)2.35739150
60Blue irides (HP:0000635)2.35442522
61Medial flaring of the eyebrow (HP:0010747)2.31826285
62Postural instability (HP:0002172)2.30320761
63Polyphagia (HP:0002591)2.29709755
64Status epilepticus (HP:0002133)2.27203269
65Genetic anticipation (HP:0003743)2.25139834
66Nephrogenic diabetes insipidus (HP:0009806)2.24811475
67Bradykinesia (HP:0002067)2.22752084
68Impaired smooth pursuit (HP:0007772)2.22630847
69Cerebral inclusion bodies (HP:0100314)2.21246215
70Protruding tongue (HP:0010808)2.20991697
71Neurofibrillary tangles (HP:0002185)2.13415801
72Resting tremor (HP:0002322)2.12546663
73Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.10772343
74Acute necrotizing encephalopathy (HP:0006965)2.08749112
75Abnormal mitochondria in muscle tissue (HP:0008316)2.08585924
76Limb dystonia (HP:0002451)2.08356776
77Abnormality of the left ventricular outflow tract (HP:0011103)2.07950371
78Subaortic stenosis (HP:0001682)2.07950371
79Lower limb muscle weakness (HP:0007340)2.07527973
80Specific learning disability (HP:0001328)2.06110901
81Increased serum pyruvate (HP:0003542)2.04975568
82Abnormality of glycolysis (HP:0004366)2.04975568
83Hemiparesis (HP:0001269)2.04803830
84Torticollis (HP:0000473)2.04692542
85Poor suck (HP:0002033)2.04328829
86Delusions (HP:0000746)2.03209715
87Focal dystonia (HP:0004373)2.01888260
88Abnormality of the lower motor neuron (HP:0002366)2.01114157
89Bundle branch block (HP:0011710)1.98309231
90Neoplasm of the peripheral nervous system (HP:0100007)1.98106312
91Progressive macrocephaly (HP:0004481)1.96752362
92Mutism (HP:0002300)1.96356645
93Apathy (HP:0000741)1.96113448
94Incomplete penetrance (HP:0003829)1.93258639
95Gait ataxia (HP:0002066)1.92384797
96Sensory axonal neuropathy (HP:0003390)1.92217477
97Abnormality of ocular smooth pursuit (HP:0000617)1.91490018
98Morphological abnormality of the pyramidal tract (HP:0002062)1.90640373
99Stereotypic behavior (HP:0000733)1.90313274
100Aplasia involving bones of the extremities (HP:0009825)1.87561072
101Aplasia involving bones of the upper limbs (HP:0009823)1.87561072
102Aplasia of the phalanges of the hand (HP:0009802)1.87561072
103Intention tremor (HP:0002080)1.86072503
104Genital tract atresia (HP:0001827)1.85626271
105Lower limb amyotrophy (HP:0007210)1.85394229
106Vaginal atresia (HP:0000148)1.84986112
107Oligomenorrhea (HP:0000876)1.84236379
108Clonus (HP:0002169)1.83380046
109Hyperparathyroidism (HP:0000843)1.83322313
110Neuronal loss in central nervous system (HP:0002529)1.82922894
111Craniofacial dystonia (HP:0012179)1.81169565
112Hyperthyroidism (HP:0000836)1.80321087
113Akinesia (HP:0002304)1.79922186
114Annular pancreas (HP:0001734)1.79733351
115Poor coordination (HP:0002370)1.78662499
116Heterotopia (HP:0002282)1.78136319
117Dynein arm defect of respiratory motile cilia (HP:0012255)1.77926457
118Absent/shortened dynein arms (HP:0200106)1.77926457
119Spastic tetraparesis (HP:0001285)1.77827242
120Failure to thrive in infancy (HP:0001531)1.77503412
121Megalencephaly (HP:0001355)1.74910567
122Cerebral hypomyelination (HP:0006808)1.71899102
123Hammertoe (HP:0001765)1.70525883
124Papilledema (HP:0001085)1.68930471
125Spastic paraplegia (HP:0001258)1.68686562
126Sleep apnea (HP:0010535)1.67007921
127Diminished motivation (HP:0000745)1.64027513
128Paraplegia (HP:0010550)1.62593925
129Sacral dimple (HP:0000960)1.61929248
130Rigidity (HP:0002063)1.61106703
131Choreoathetosis (HP:0001266)1.59664571
132Relative macrocephaly (HP:0004482)1.56721063
133Atrioventricular block (HP:0001678)1.55678159
134Distal sensory impairment (HP:0002936)1.55661007
135Ankyloglossia (HP:0010296)1.55562991
136Turricephaly (HP:0000262)1.54946008

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.45202239
2NTRK33.82740977
3EPHA43.77256962
4MAP3K43.42043665
5MAP2K73.37821682
6MAP3K122.90353941
7MAP3K92.67354010
8DAPK22.63644564
9CDK192.49955725
10MINK12.33900559
11MAP2K42.28978407
12PLK22.23098893
13MARK12.20152741
14DAPK11.94634111
15RIPK41.85685865
16OXSR11.79152158
17PRPF4B1.63942998
18AKT31.63017292
19SCYL21.59762338
20PAK61.56627078
21NTRK21.53547563
22GRK51.53335836
23CCNB11.47240289
24ICK1.43319424
25PNCK1.41804236
26PRKD31.36669295
27PDK31.36269587
28PDK41.36269587
29NTRK11.35161494
30PBK1.34817636
31ARAF1.34284766
32CDK51.32783798
33RIPK11.27602859
34PRKCG1.27594347
35KSR21.25427004
36CAMKK11.21437201
37SGK2231.20580589
38SGK4941.20580589
39TSSK61.16357911
40KSR11.13474928
41CAMK2A1.12476095
42MAPK131.11794901
43TNIK1.07502951
44CAMKK21.07170351
45SGK21.06445748
46BMPR21.02630476
47CAMK2B1.01721248
48NME10.99807646
49STK390.93030057
50PTK2B0.90163415
51PDGFRA0.89079078
52WEE10.86668697
53FES0.85395796
54CDK180.83586201
55DMPK0.80895133
56UHMK10.80351737
57PRKCE0.79430303
58CDK140.78876818
59PDK20.78714102
60ALK0.78250850
61CDK150.77562012
62LATS10.76484395
63STK380.74877664
64BCR0.74866291
65MAPK100.74708383
66SGK30.72819307
67MKNK20.68953949
68PRKCH0.68546030
69CSNK1G20.68317903
70PINK10.66787742
71MOS0.66553526
72PHKG10.66130947
73PHKG20.66130947
74SIK30.66127083
75LIMK10.65912651
76CDK11A0.65092089
77SGK10.64374702
78BRSK10.64223267
79BRAF0.63682302
80STK110.62599136
81CAMK2D0.62443846
82PDK10.61705950
83CAMK10.61635967
84MAP3K20.60832101
85PDPK10.60202611
86CAMK2G0.57845369
87MAPKAPK50.55656991
88ERBB40.55507554
89PTK20.54860091
90FGR0.54144259
91WNK10.53570808
92MUSK0.52092896
93DYRK1A0.52054076
94RET0.51841001
95CAMK40.51810123
96DAPK30.51710976
97MAP3K60.50882579
98MARK20.50844819
99RPS6KB10.49519461
100CAMK1G0.49213570
101NEK10.48229241
102PAK30.47029303
103TYRO30.46265330
104CSNK1E0.46057596
105MAP3K130.45739333
106NEK60.45284808
107LATS20.45050516
108GRK70.45049625
109WNK30.44402968
110RAF10.44204364
111TNK20.43474715
112ERBB30.43204650
113MAPK120.42052983
114ADRBK10.41683108
115SIK20.41650919
116MAP3K10.40800232
117ROCK20.39698541
118RPS6KA30.38761703
119ADRBK20.37606122
120MAP2K10.37573911
121FER0.36102082
122PKN10.35286922
123TTN0.34916839
124MKNK10.33780528
125PAK20.32707172
126AKT20.30870579
127TTK0.30002186
128BRD40.29921287
129PRKCZ0.29771283
130EEF2K0.28546586

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.02388010
2Synaptic vesicle cycle_Homo sapiens_hsa047213.90740862
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.83716738
4GABAergic synapse_Homo sapiens_hsa047272.78763097
5Collecting duct acid secretion_Homo sapiens_hsa049662.77646995
6Olfactory transduction_Homo sapiens_hsa047402.60570638
7Morphine addiction_Homo sapiens_hsa050322.55623903
8Circadian entrainment_Homo sapiens_hsa047132.53405882
9Long-term potentiation_Homo sapiens_hsa047202.52688860
10Glutamatergic synapse_Homo sapiens_hsa047242.41109211
11Amphetamine addiction_Homo sapiens_hsa050312.40873513
12Dopaminergic synapse_Homo sapiens_hsa047282.14089860
13Salivary secretion_Homo sapiens_hsa049701.99524534
14Taste transduction_Homo sapiens_hsa047421.88060458
15Insulin secretion_Homo sapiens_hsa049111.83789199
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.77087018
17Phototransduction_Homo sapiens_hsa047441.76568889
18Serotonergic synapse_Homo sapiens_hsa047261.70579244
19Vibrio cholerae infection_Homo sapiens_hsa051101.65696251
20Renin secretion_Homo sapiens_hsa049241.63370702
21Gastric acid secretion_Homo sapiens_hsa049711.61585069
22Cholinergic synapse_Homo sapiens_hsa047251.60737458
23Long-term depression_Homo sapiens_hsa047301.58153345
24Calcium signaling pathway_Homo sapiens_hsa040201.51331600
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.47066708
26Prion diseases_Homo sapiens_hsa050201.46690786
27Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.46488759
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.44676760
29Oxytocin signaling pathway_Homo sapiens_hsa049211.42668248
30Cocaine addiction_Homo sapiens_hsa050301.42456502
31Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.40128304
32Oxidative phosphorylation_Homo sapiens_hsa001901.37936140
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.35158650
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28772742
35Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.27555664
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18407948
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.17060565
38GnRH signaling pathway_Homo sapiens_hsa049121.09486529
39Gap junction_Homo sapiens_hsa045401.07954322
40Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.05871860
41cAMP signaling pathway_Homo sapiens_hsa040241.05789439
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05447998
43Cardiac muscle contraction_Homo sapiens_hsa042601.03698870
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01860069
45Alzheimers disease_Homo sapiens_hsa050101.00488443
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.99667482
47Thyroid hormone signaling pathway_Homo sapiens_hsa049190.95682373
48ErbB signaling pathway_Homo sapiens_hsa040120.90478000
49cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90256994
50Parkinsons disease_Homo sapiens_hsa050120.90155663
51Hippo signaling pathway_Homo sapiens_hsa043900.89115543
52Axon guidance_Homo sapiens_hsa043600.88918496
53Estrogen signaling pathway_Homo sapiens_hsa049150.86343247
54Type II diabetes mellitus_Homo sapiens_hsa049300.83821422
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.83202564
56Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.82674168
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.79030047
58Wnt signaling pathway_Homo sapiens_hsa043100.75959762
59Glioma_Homo sapiens_hsa052140.75863353
60Melanogenesis_Homo sapiens_hsa049160.72332343
61Endometrial cancer_Homo sapiens_hsa052130.72227108
62Rheumatoid arthritis_Homo sapiens_hsa053230.72153190
63Pyruvate metabolism_Homo sapiens_hsa006200.68662191
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.66455293
65Pancreatic secretion_Homo sapiens_hsa049720.66348314
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.65641668
67Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65252517
68SNARE interactions in vesicular transport_Homo sapiens_hsa041300.63355527
69Oocyte meiosis_Homo sapiens_hsa041140.63103273
70Longevity regulating pathway - mammal_Homo sapiens_hsa042110.61466977
71Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61188100
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.59750951
73MAPK signaling pathway_Homo sapiens_hsa040100.58540177
74Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.55893287
75mTOR signaling pathway_Homo sapiens_hsa041500.55530534
76Butanoate metabolism_Homo sapiens_hsa006500.55096424
77Adherens junction_Homo sapiens_hsa045200.54856479
78Glucagon signaling pathway_Homo sapiens_hsa049220.54674900
79Type I diabetes mellitus_Homo sapiens_hsa049400.54632610
80Thyroid hormone synthesis_Homo sapiens_hsa049180.54119270
81Huntingtons disease_Homo sapiens_hsa050160.53739458
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52241745
83Dilated cardiomyopathy_Homo sapiens_hsa054140.52137646
84Chronic myeloid leukemia_Homo sapiens_hsa052200.50895232
85Ras signaling pathway_Homo sapiens_hsa040140.50568409
86Proteoglycans in cancer_Homo sapiens_hsa052050.50411314
87mRNA surveillance pathway_Homo sapiens_hsa030150.50061283
88Central carbon metabolism in cancer_Homo sapiens_hsa052300.49954296
89Dorso-ventral axis formation_Homo sapiens_hsa043200.49803007
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47580970
91Focal adhesion_Homo sapiens_hsa045100.47338215
92Phagosome_Homo sapiens_hsa041450.46963660
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46878007
94Tight junction_Homo sapiens_hsa045300.46588229
95Inositol phosphate metabolism_Homo sapiens_hsa005620.46116536
96Circadian rhythm_Homo sapiens_hsa047100.44447981
97Vitamin B6 metabolism_Homo sapiens_hsa007500.43394242
98Colorectal cancer_Homo sapiens_hsa052100.43298342
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.42980502
100AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.42483196
101Prolactin signaling pathway_Homo sapiens_hsa049170.41871747
102AMPK signaling pathway_Homo sapiens_hsa041520.41547952
103Non-small cell lung cancer_Homo sapiens_hsa052230.41511768
104MicroRNAs in cancer_Homo sapiens_hsa052060.41398355
105Choline metabolism in cancer_Homo sapiens_hsa052310.40372788
106Melanoma_Homo sapiens_hsa052180.39756715
107Hedgehog signaling pathway_Homo sapiens_hsa043400.39327933
108Fatty acid biosynthesis_Homo sapiens_hsa000610.38691163
109Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38205411
110Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37535765
111Fatty acid elongation_Homo sapiens_hsa000620.36343975
112Alcoholism_Homo sapiens_hsa050340.32516128
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.31884500
114Rap1 signaling pathway_Homo sapiens_hsa040150.31002592
115Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.29990363
116Endocytosis_Homo sapiens_hsa041440.28408520
117Neurotrophin signaling pathway_Homo sapiens_hsa047220.26661838
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.26422243
119Renal cell carcinoma_Homo sapiens_hsa052110.26193075
120Bile secretion_Homo sapiens_hsa049760.25302859
121Insulin signaling pathway_Homo sapiens_hsa049100.25010996
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.24799764
123Ovarian steroidogenesis_Homo sapiens_hsa049130.23219406
124African trypanosomiasis_Homo sapiens_hsa051430.23165641
125VEGF signaling pathway_Homo sapiens_hsa043700.23094508
126Arginine biosynthesis_Homo sapiens_hsa002200.22658966
127Regulation of autophagy_Homo sapiens_hsa041400.22163655

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