SMIM24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fusion of sperm to egg plasma membrane (GO:0007342)9.75186497
2cilium or flagellum-dependent cell motility (GO:0001539)9.30679695
3acrosome reaction (GO:0007340)8.71921697
4sperm-egg recognition (GO:0035036)8.66759453
5acrosome assembly (GO:0001675)8.51801779
6cell wall macromolecule metabolic process (GO:0044036)8.23733850
7cell wall macromolecule catabolic process (GO:0016998)8.23733850
8multicellular organism reproduction (GO:0032504)8.00436341
9axonemal dynein complex assembly (GO:0070286)7.95549706
10sperm capacitation (GO:0048240)7.94846657
11binding of sperm to zona pellucida (GO:0007339)7.91907420
12cell-cell recognition (GO:0009988)7.76938559
13spermatid development (GO:0007286)7.62158861
14motile cilium assembly (GO:0044458)7.31169047
15intestinal absorption (GO:0050892)7.31007846
16epithelial cilium movement (GO:0003351)7.24294825
17plasma membrane fusion (GO:0045026)7.22796723
18piRNA metabolic process (GO:0034587)7.08370168
19reproduction (GO:0000003)6.81939007
20angiotensin maturation (GO:0002003)6.61971983
21regulation of cilium movement (GO:0003352)6.55701686
22intestinal cholesterol absorption (GO:0030299)6.43526561
23organic cation transport (GO:0015695)6.35297101
24cilium movement (GO:0003341)6.03991989
25male meiosis (GO:0007140)6.01868562
26synaptonemal complex organization (GO:0070193)5.90713763
27synaptonemal complex assembly (GO:0007130)5.76855313
28epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.68078310
29single fertilization (GO:0007338)5.54164428
30regulation of guanylate cyclase activity (GO:0031282)5.35619455
31epoxygenase P450 pathway (GO:0019373)5.11955219
32NADH metabolic process (GO:0006734)4.95324748
33spermatogenesis (GO:0007283)4.91298878
34fertilization (GO:0009566)4.90851356
35male gamete generation (GO:0048232)4.89451533
36seminiferous tubule development (GO:0072520)4.85490870
37fat-soluble vitamin biosynthetic process (GO:0042362)4.83516182
38negative regulation of inclusion body assembly (GO:0090084)4.74753933
39peptide hormone processing (GO:0016486)4.70542394
40vitamin A metabolic process (GO:0006776)4.67682878
41regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.61563528
42male meiosis I (GO:0007141)4.52521265
43gamete generation (GO:0007276)4.46895413
44positive regulation of guanylate cyclase activity (GO:0031284)4.25565744
45cellular process involved in reproduction in multicellular organism (GO:0022412)4.22762979
46DNA methylation involved in gamete generation (GO:0043046)4.20447837
47germ cell development (GO:0007281)4.19782791
48lipoprotein transport (GO:0042953)4.14109077
49regulation of bile acid biosynthetic process (GO:0070857)4.11081749
50drug metabolic process (GO:0017144)4.08971407
51sulfate transmembrane transport (GO:1902358)4.03266541
52alditol metabolic process (GO:0019400)3.99654688
53chromosome organization involved in meiosis (GO:0070192)3.91634724
54glucose 6-phosphate metabolic process (GO:0051156)3.84190063
55regulation of inclusion body assembly (GO:0090083)3.69550891
56peptide catabolic process (GO:0043171)3.69071295
57carnitine transport (GO:0015879)3.68499154
58amino-acid betaine transport (GO:0015838)3.68499154
59hormone catabolic process (GO:0042447)3.66744224
60glycerol ether metabolic process (GO:0006662)3.66476226
61glycerol metabolic process (GO:0006071)3.65712470
62flavonoid metabolic process (GO:0009812)3.65652085
63positive regulation of lipoprotein lipase activity (GO:0051006)3.65556559
64positive regulation of triglyceride lipase activity (GO:0061365)3.65556559
65microtubule depolymerization (GO:0007019)3.61656554
66regulation of microtubule-based movement (GO:0060632)3.59735080
67chromosome condensation (GO:0030261)3.58374966
68meiosis I (GO:0007127)3.58001876
69adhesion of symbiont to host cell (GO:0044650)3.54307983
70virion attachment to host cell (GO:0019062)3.54307983
71meiotic nuclear division (GO:0007126)3.53687546
72multicellular organismal reproductive process (GO:0048609)3.52911756
73regulation of cGMP biosynthetic process (GO:0030826)3.52594355
74calcium ion-dependent exocytosis (GO:0017156)3.51264680
75fructose metabolic process (GO:0006000)3.50775591
76regulation of systemic arterial blood pressure by hormone (GO:0001990)3.46970601
77regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.46970601
78endocrine process (GO:0050886)3.46970601
79regulation of cellular extravasation (GO:0002691)3.46791673
80uronic acid metabolic process (GO:0006063)3.43215179
81glucuronate metabolic process (GO:0019585)3.43215179
82positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003573.40265726
83quinone biosynthetic process (GO:1901663)3.40138614
84vitamin biosynthetic process (GO:0009110)3.40089546
85drug catabolic process (GO:0042737)3.38923287
86DNA packaging (GO:0006323)3.38365226
87ventricular system development (GO:0021591)3.37216874
88regulation of triglyceride catabolic process (GO:0010896)3.37133474
89auditory receptor cell differentiation (GO:0042491)3.36708512
90ether metabolic process (GO:0018904)3.35238777
91L-ascorbic acid metabolic process (GO:0019852)3.30245430
92sulfate transport (GO:0008272)3.29636111
93transepithelial transport (GO:0070633)3.29414976
94exogenous drug catabolic process (GO:0042738)3.27254817
95cellular glucuronidation (GO:0052695)3.21681745
96carnitine transmembrane transport (GO:1902603)3.19513683
97cellular carbohydrate catabolic process (GO:0044275)3.19404338
98drug transmembrane transport (GO:0006855)3.19314273
99digestive system process (GO:0022600)3.19128187
100cell recognition (GO:0008037)3.16545230
101drug transport (GO:0015893)3.14738224
102phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.11017308
103meiotic cell cycle (GO:0051321)3.10522826
104alkaloid metabolic process (GO:0009820)3.08087341
105glycolytic process (GO:0006096)3.07938160
106left/right pattern formation (GO:0060972)3.07310746
107diacylglycerol metabolic process (GO:0046339)3.05542590
1083-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.04344733
109purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.04344733
110drinking behavior (GO:0042756)3.04295872
111high-density lipoprotein particle remodeling (GO:0034375)3.04071799
112receptor guanylyl cyclase signaling pathway (GO:0007168)3.02694057
113polyol transport (GO:0015791)3.02492982
114regulation of systemic arterial blood pressure (GO:0003073)3.02415438
115arginine metabolic process (GO:0006525)3.01538436
116microtubule severing (GO:0051013)2.99487144
117interferon-gamma secretion (GO:0072643)2.99176102
118urate metabolic process (GO:0046415)2.99069640
119genitalia morphogenesis (GO:0035112)2.98649341
120purine deoxyribonucleotide catabolic process (GO:0009155)2.98532674
121quaternary ammonium group transport (GO:0015697)2.97502700
122triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.94110396
123bile acid and bile salt transport (GO:0015721)2.93641655
124phenol-containing compound catabolic process (GO:0019336)2.93547497
125modified amino acid transport (GO:0072337)2.93206631
126cobalamin metabolic process (GO:0009235)2.92143061
127digestion (GO:0007586)2.91469365
128erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.90155611
129L-phenylalanine catabolic process (GO:0006559)2.90155611
130regulation of B cell apoptotic process (GO:0002902)2.89430048
131vitamin transport (GO:0051180)2.89363850
132polyol catabolic process (GO:0046174)2.88347644
133antibacterial humoral response (GO:0019731)2.86843871
134adhesion of symbiont to host (GO:0044406)2.86835044
135actin filament depolymerization (GO:0030042)2.85568591
136cytochrome complex assembly (GO:0017004)2.85527170
137regulation of cholesterol esterification (GO:0010872)2.85091249
138sphingomyelin metabolic process (GO:0006684)2.84560886
139multicellular organismal development (GO:0007275)2.84422058
140phospholipid efflux (GO:0033700)2.83718358
141sulfur compound transport (GO:0072348)2.82969218
142regulation of cGMP metabolic process (GO:0030823)2.80897143
143protein-lipid complex remodeling (GO:0034368)2.80873848
144macromolecular complex remodeling (GO:0034367)2.80873848
145plasma lipoprotein particle remodeling (GO:0034369)2.80873848
146ethanol oxidation (GO:0006069)2.80345073
147oxaloacetate metabolic process (GO:0006107)2.80136670
148antimicrobial humoral response (GO:0019730)2.78501933
149fat-soluble vitamin metabolic process (GO:0006775)2.78375474
150short-chain fatty acid metabolic process (GO:0046459)2.78280212
151reverse cholesterol transport (GO:0043691)2.76613046
152urea cycle (GO:0000050)2.76349406
153mRNA modification (GO:0016556)2.75651141
154positive regulation of cGMP biosynthetic process (GO:0030828)2.75171248
155response to hydroperoxide (GO:0033194)2.74715271
156antigen processing and presentation of endogenous antigen (GO:0019883)2.74391956
157urea metabolic process (GO:0019627)2.72937091
158thrombin receptor signaling pathway (GO:0070493)2.71331304
159very-low-density lipoprotein particle assembly (GO:0034379)2.70990068
160cytidine metabolic process (GO:0046087)2.70787530
161cytidine catabolic process (GO:0006216)2.70787530
162cytidine deamination (GO:0009972)2.70787530
163respiratory chain complex IV assembly (GO:0008535)2.69321019
164peptide metabolic process (GO:0006518)2.69061655
165lipoprotein metabolic process (GO:0042157)2.67345273
166positive regulation of icosanoid secretion (GO:0032305)2.66127446
167regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.66123052
168L-fucose catabolic process (GO:0042355)2.65012049
169fucose catabolic process (GO:0019317)2.65012049
170L-fucose metabolic process (GO:0042354)2.65012049
171glutathione derivative metabolic process (GO:1901685)2.64099288
172glutathione derivative biosynthetic process (GO:1901687)2.64099288
173NAD metabolic process (GO:0019674)2.63906333
174nitrogen cycle metabolic process (GO:0071941)2.63427504
175leukotriene metabolic process (GO:0006691)2.61844765
176glutamine family amino acid biosynthetic process (GO:0009084)2.60271303
177glycoside metabolic process (GO:0016137)2.59706621
178positive regulation of respiratory burst (GO:0060267)2.58985655
179hydrogen peroxide catabolic process (GO:0042744)2.58004688
180glycolipid catabolic process (GO:0019377)2.57654620
181cGMP biosynthetic process (GO:0006182)2.56556729
182fatty acid catabolic process (GO:0009062)2.55789557
183quinone metabolic process (GO:1901661)2.55782468
184sperm motility (GO:0030317)10.4414623

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.56450765
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.52077269
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.50695882
4BP1_19119308_ChIP-ChIP_Hs578T_Human3.18161660
5TP63_17297297_ChIP-ChIP_HaCaT_Human2.94289792
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.91548311
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.83333263
8GATA1_22025678_ChIP-Seq_K562_Human2.46501873
9RXR_22158963_ChIP-Seq_LIVER_Mouse2.44279804
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.43832395
11PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.38473125
12VDR_22108803_ChIP-Seq_LS180_Human2.34595526
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.32403160
14GATA1_26923725_Chip-Seq_HPCs_Mouse2.29356218
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.25299505
16EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.24059029
17SCL_19346495_ChIP-Seq_HPC-7_Human2.14620556
18SOX2_27498859_Chip-Seq_STOMACH_Mouse2.11866791
19CDX2_20551321_ChIP-Seq_CACO-2_Human2.06317424
20STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.00470460
21EZH2_22144423_ChIP-Seq_EOC_Human1.99334673
22SRY_22984422_ChIP-ChIP_TESTIS_Rat1.90478463
23FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.88988016
24GATA3_21867929_ChIP-Seq_CD8_Mouse1.82449134
25STAT1_17558387_ChIP-Seq_HELA_Human1.78090566
26GATA4_25053715_ChIP-Seq_YYC3_Human1.76490869
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.70346975
28KAP1_22055183_ChIP-Seq_ESCs_Mouse1.69060089
29CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.65149742
30RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.64824202
31CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.64305650
32CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.59241073
33SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57417133
34SOX2_22085726_ChIP-Seq_NPCs_Mouse1.56583138
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.55984902
36BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.52988473
37FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.51525865
38RAD21_21589869_ChIP-Seq_MESCs_Mouse1.50527496
39BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.47809008
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.46816888
41IRF8_21731497_ChIP-ChIP_J774_Mouse1.46592183
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46321603
43BCOR_27268052_Chip-Seq_Bcells_Human1.44666452
44AR_20517297_ChIP-Seq_VCAP_Human1.44139115
45NANOG_20526341_ChIP-Seq_ESCs_Human1.42741003
46LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.41143183
47BCL6_27268052_Chip-Seq_Bcells_Human1.39049054
48PPARA_22158963_ChIP-Seq_LIVER_Mouse1.38924804
49CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37901814
50MYB_26560356_Chip-Seq_TH2_Human1.37900236
51P53_21459846_ChIP-Seq_SAOS-2_Human1.35705774
52VDR_24763502_ChIP-Seq_THP-1_Human1.35197289
53RARA_24833708_ChIP-Seq_LIVER_Mouse1.34955073
54NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.34498595
55GATA6_25053715_ChIP-Seq_YYC3_Human1.34364728
56PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.33411384
57PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.32131501
58GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.30953189
59SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30775236
60PHF8_20622854_ChIP-Seq_HELA_Human1.30009333
61EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.29664862
62LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse1.29125310
63IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.28352260
64PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.27973803
65ETV2_25802403_ChIP-Seq_MESCs_Mouse1.27949909
66ELK4_26923725_Chip-Seq_MESODERM_Mouse1.27540562
67ERG_20517297_ChIP-Seq_VCAP_Human1.27315145
68SOX2_20726797_ChIP-Seq_SW620_Human1.27288882
69SRF_21415370_ChIP-Seq_HL-1_Mouse1.25962706
70ZNF274_21170338_ChIP-Seq_K562_Hela1.25278968
71HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.24680724
72CEBPB_22108803_ChIP-Seq_LS180_Human1.24163395
73SPI1_23547873_ChIP-Seq_NB4_Human1.24031090
74FOXA1_21572438_ChIP-Seq_LNCaP_Human1.23982656
75PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.22359538
76FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.21966633
77E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.21641310
78MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.21389048
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.21171524
80TAF2_19829295_ChIP-Seq_ESCs_Human1.20935456
81TET1_21451524_ChIP-Seq_MESCs_Mouse1.20854880
82CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20576104
83FOXA1_25552417_ChIP-Seq_VCAP_Human1.19976673
84SOX2_21211035_ChIP-Seq_LN229_Human1.19775296
85AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.18858574
86CTCF_20526341_ChIP-Seq_ESCs_Human1.17432160
87LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.17008878
88TAL1_26923725_Chip-Seq_HPCs_Mouse1.16501223
89STAT1_20625510_ChIP-Seq_HELA_Human1.16246338
90SPI1_26923725_Chip-Seq_HPCs_Mouse1.14531753
91CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13601985
92LXR_22158963_ChIP-Seq_LIVER_Mouse1.13318969
93CTCF_26484167_Chip-Seq_Bcells_Mouse1.12425818
94PCGF2_27294783_Chip-Seq_ESCs_Mouse1.12082990
95PCGF2_27294783_Chip-Seq_NPCs_Mouse1.11839329
96YY1_22570637_ChIP-Seq_MALME-3M_Human1.11824883
97RXRA_24833708_ChIP-Seq_LIVER_Mouse1.11560771
98JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.11542924
99ESET_19884257_ChIP-Seq_ESCs_Mouse1.11479461
100SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.10753765
101FLI1_27457419_Chip-Seq_LIVER_Mouse1.10581663
102IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.10351308
103LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.09998794
104GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.09795911
105FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09316877
106PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08523121
107GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.08377681
108SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.08242095
109EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07818115
110NCOR_22424771_ChIP-Seq_293T_Human1.07794318
111ELF1_20517297_ChIP-Seq_JURKAT_Human1.07147525
112HTT_18923047_ChIP-ChIP_STHdh_Human1.07077254
113WDR5_24793694_ChIP-Seq_LNCAP_Human1.04380925
114GATA3_26560356_Chip-Seq_TH2_Human1.04255612
115GATA3_21878914_ChIP-Seq_MCF-7_Human1.04138651
116FLI1_21867929_ChIP-Seq_CD8_Mouse1.03654674
117GATA2_19941826_ChIP-Seq_K562_Human1.02996921
118CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.02945470
119MYB_26560356_Chip-Seq_TH1_Human1.02852137
120FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.02734021
121PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.02678568
122VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.02453159
123GATA1_19941826_ChIP-Seq_K562_Human1.02451812
124HNF4A_19822575_ChIP-Seq_HepG2_Human1.02210383
125MYC_19829295_ChIP-Seq_ESCs_Human1.01562037
126GATA3_21867929_ChIP-Seq_TH1_Mouse1.01401739
127GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01099474
128FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.00908956
129P300_27268052_Chip-Seq_Bcells_Human1.00158061
130RUNX1_27514584_Chip-Seq_MCF-7_Human0.99852435
131TP63_22573176_ChIP-Seq_HFKS_Human0.99695104
132GATA3_27048872_Chip-Seq_THYMUS_Human0.99472293
133E2F1_20622854_ChIP-Seq_HELA_Human0.98935529
134CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98856473
135GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.98605726
136CDX2_22108803_ChIP-Seq_LS180_Human0.98167968
137NFE2_27457419_Chip-Seq_LIVER_Mouse0.98105287
138RUNX1_26923725_Chip-Seq_HPCs_Mouse0.97813608
139BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97779749
140CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.97209993
141VDR_21846776_ChIP-Seq_THP-1_Human0.96497867
142EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.96429408
143E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.95917903
144ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.95420102
145GATA1_19941827_ChIP-Seq_MEL86_Mouse0.95394026
146TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94979588
147FOXA1_27270436_Chip-Seq_PROSTATE_Human0.94677809
148FOXA1_25329375_ChIP-Seq_VCAP_Human0.94677809
149TP53_22573176_ChIP-Seq_HFKS_Human0.94674723
150ERA_21632823_ChIP-Seq_H3396_Human0.94196976
151RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.94160961
152RAC3_21632823_ChIP-Seq_H3396_Human0.93990679
153TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.92781872
154GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91903362
155SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.91853547
156SA1_27219007_Chip-Seq_Bcells_Human0.91834888
157CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91513218
158CTCF_18555785_ChIP-Seq_MESCs_Mouse0.89717862
159EGR1_23403033_ChIP-Seq_LIVER_Mouse0.87526641
160KDM2B_26808549_Chip-Seq_REH_Human0.86463419

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis6.91127871
2MP0001666_abnormal_nutrient_absorption4.23057696
3MP0003698_abnormal_male_reproductive3.68084846
4MP0001929_abnormal_gametogenesis3.40411159
5MP0004264_abnormal_extraembryonic_tissu2.88229109
6MP0003183_abnormal_peptide_metabolism2.79772105
7MP0002139_abnormal_hepatobiliary_system2.72102632
8MP0009840_abnormal_foam_cell2.46220805
9MP0010234_abnormal_vibrissa_follicle2.42483968
10MP0003866_abnormal_defecation2.35886031
11MP0000462_abnormal_digestive_system2.26624527
12MP0008877_abnormal_DNA_methylation2.21822367
13MP0003252_abnormal_bile_duct2.20004565
14MP0008875_abnormal_xenobiotic_pharmacok2.19326392
15MP0003878_abnormal_ear_physiology2.18399026
16MP0005377_hearing/vestibular/ear_phenot2.18399026
17MP0004019_abnormal_vitamin_homeostasis2.17081569
18MP0002396_abnormal_hematopoietic_system2.13140857
19MP0002210_abnormal_sex_determination2.06767681
20MP0001873_stomach_inflammation2.02235498
21MP0005410_abnormal_fertilization10.3823458
22MP0002161_abnormal_fertility/fecundity1.92079581
23MP0001145_abnormal_male_reproductive1.86268878
24MP0005085_abnormal_gallbladder_physiolo1.85810544
25MP0004043_abnormal_pH_regulation1.81617257
26MP0001765_abnormal_ion_homeostasis1.72140062
27MP0005645_abnormal_hypothalamus_physiol1.67986818
28MP0010329_abnormal_lipoprotein_level1.65891800
29MP0000013_abnormal_adipose_tissue1.61906498
30MP0010155_abnormal_intestine_physiology1.57791049
31MP0000653_abnormal_sex_gland1.56497621
32MP0005084_abnormal_gallbladder_morpholo1.53227947
33MP0001663_abnormal_digestive_system1.51687434
34MP0000490_abnormal_crypts_of1.50725632
35MP0001664_abnormal_digestion1.43526548
36MP0005381_digestive/alimentary_phenotyp1.42243405
37MP0002653_abnormal_ependyma_morphology1.37902123
38MP0004147_increased_porphyrin_level1.35297472
39MP0005365_abnormal_bile_salt1.34783291
40MP0002822_catalepsy1.34471631
41MP0005535_abnormal_body_temperature1.34132350
42MP0005636_abnormal_mineral_homeostasis1.34114018
43MP0002837_dystrophic_cardiac_calcinosis1.30432092
44MP0009643_abnormal_urine_homeostasis1.27722840
45MP0003195_calcinosis1.25711152
46MP0005646_abnormal_pituitary_gland1.25133090
47MP0003300_gastrointestinal_ulcer1.25094435
48MP0001501_abnormal_sleep_pattern1.24082853
49MP0005075_abnormal_melanosome_morpholog1.18650868
50MP0000477_abnormal_intestine_morphology1.15277802
51MP0000537_abnormal_urethra_morphology1.13198204
52MP0002138_abnormal_hepatobiliary_system1.12116503
53MP0005220_abnormal_exocrine_pancreas1.10767833
54MP0002693_abnormal_pancreas_physiology1.09252374
55MP0009697_abnormal_copulation1.08250553
56MP0006054_spinal_hemorrhage1.08150455
57MP0005332_abnormal_amino_acid1.08088820
58MP0001764_abnormal_homeostasis1.07695060
59MP0000230_abnormal_systemic_arterial1.07350535
60MP0005670_abnormal_white_adipose1.03392949
61MP0008004_abnormal_stomach_pH1.03193770
62MP0002166_altered_tumor_susceptibility1.02793560
63MP0002078_abnormal_glucose_homeostasis1.02134828
64MP0003868_abnormal_feces_composition1.01559346
65MP0009379_abnormal_foot_pigmentation1.01371578
66MP0005174_abnormal_tail_pigmentation1.00802216
67MP0000465_gastrointestinal_hemorrhage1.00364853
68MP0003787_abnormal_imprinting0.99635267
69MP0000538_abnormal_urinary_bladder0.98457381
70MP0002796_impaired_skin_barrier0.97261466
71MP0004782_abnormal_surfactant_physiolog0.93937100
72MP0002909_abnormal_adrenal_gland0.93788634
73MP0003172_abnormal_lysosome_physiology0.92409804
74MP0010352_gastrointestinal_tract_polyps0.89665285
75MP0005379_endocrine/exocrine_gland_phen0.89461450
76MP0002136_abnormal_kidney_physiology0.84716808
77MP0003638_abnormal_response/metabolism_0.83736129
78MP0003724_increased_susceptibility_to0.82719114
79MP0001188_hyperpigmentation0.82553388
80MP0001986_abnormal_taste_sensitivity0.82339934
81MP0001944_abnormal_pancreas_morphology0.81133765
82MP0002971_abnormal_brown_adipose0.80409159
83MP0005448_abnormal_energy_balance0.79579422
84MP0005409_darkened_coat_color0.77865044
85MP0001905_abnormal_dopamine_level0.77130852
86MP0002160_abnormal_reproductive_system0.76915208
87MP0003953_abnormal_hormone_level0.76307115
88MP0002006_tumorigenesis0.76149058
89MP0000681_abnormal_thyroid_gland0.76075576
90MP0003283_abnormal_digestive_organ0.75950426
91MP0005367_renal/urinary_system_phenotyp0.74819860
92MP0000516_abnormal_urinary_system0.74819860
93MP0003303_peritoneal_inflammation0.73565568
94MP0002118_abnormal_lipid_homeostasis0.71672302
95MP0004947_skin_inflammation0.70154846
96MP0009764_decreased_sensitivity_to0.70040814
97MP0003191_abnormal_cellular_cholesterol0.69511772
98MP0003315_abnormal_perineum_morphology0.68512101
99MP0000609_abnormal_liver_physiology0.68438216
100MP0009780_abnormal_chondrocyte_physiolo0.68228206
101MP0005319_abnormal_enzyme/_coenzyme0.68059647
102MP0005058_abnormal_lysosome_morphology0.67939209
103MP0005387_immune_system_phenotype0.67401968
104MP0001790_abnormal_immune_system0.67401968
105MP0002089_abnormal_postnatal_growth/wei0.67188206
106MP0003879_abnormal_hair_cell0.64169297
107MP0003646_muscle_fatigue0.63771450
108MP0003806_abnormal_nucleotide_metabolis0.61315272
109MP0003693_abnormal_embryo_hatching0.60418651
110MP0005397_hematopoietic_system_phenotyp0.58994988
111MP0001545_abnormal_hematopoietic_system0.58994988
112MP0005501_abnormal_skin_physiology0.57895604
113MP0002876_abnormal_thyroid_physiology0.57618729
114MP0009785_altered_susceptibility_to0.57293658
115MP0005584_abnormal_enzyme/coenzyme_acti0.56812397
116MP0008872_abnormal_physiological_respon0.56451596
117MP0001849_ear_inflammation0.55500426
118MP0006036_abnormal_mitochondrial_physio0.55217290
119MP0002148_abnormal_hypersensitivity_rea0.55129544
120MP0005464_abnormal_platelet_physiology0.54369667
121MP0009642_abnormal_blood_homeostasis0.54206664
122MP0005451_abnormal_body_composition0.52815379
123MP0001845_abnormal_inflammatory_respons0.52366266
124MP0005025_abnormal_response_to0.51909323
125MP0002254_reproductive_system_inflammat0.50631593
126MP0009115_abnormal_fat_cell0.50484610
127MP0008469_abnormal_protein_level0.49903463
128MP0000470_abnormal_stomach_morphology0.49217624
129MP0005167_abnormal_blood-brain_barrier0.48784797
130MP0000678_abnormal_parathyroid_gland0.48421550
131MP0005266_abnormal_metabolism0.44951473
132MP0003718_maternal_effect0.42852866
133MP0001756_abnormal_urination0.41966487
134MP0002405_respiratory_system_inflammati0.40293298
135MP0002132_abnormal_respiratory_system0.39732673
136MP0001216_abnormal_epidermal_layer0.36256979
137MP0005166_decreased_susceptibility_to0.35057955
138MP0003436_decreased_susceptibility_to0.34030386
139MP0005666_abnormal_adipose_tissue0.33404763
140MP0000598_abnormal_liver_morphology0.33182837
141MP0001835_abnormal_antigen_presentation0.32906705

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)7.09861320
2Abnormal respiratory motile cilium morphology (HP:0005938)6.88726289
3Abnormal respiratory epithelium morphology (HP:0012253)6.88726289
4Rhinitis (HP:0012384)6.05290235
5Chronic bronchitis (HP:0004469)5.90733322
6Nasal polyposis (HP:0100582)5.90717676
7Infertility (HP:0000789)5.67171842
8Abnormal ciliary motility (HP:0012262)5.43074656
9Abnormality of the nasal mucosa (HP:0000433)4.93855487
10Ileus (HP:0002595)4.37229873
11Bronchiectasis (HP:0002110)4.14201527
12Male infertility (HP:0003251)4.10274817
13Bronchitis (HP:0012387)4.09937154
14Abnormality of glutamine family amino acid metabolism (HP:0010902)3.93835779
15Acanthocytosis (HP:0001927)3.70151325
16Malnutrition (HP:0004395)3.68503177
17Abnormality of vitamin metabolism (HP:0100508)3.54375262
18Autoimmune thrombocytopenia (HP:0001973)3.34255138
19Dicarboxylic aciduria (HP:0003215)3.27908955
20Abnormality of dicarboxylic acid metabolism (HP:0010995)3.27908955
21Abnormal spermatogenesis (HP:0008669)3.19812180
22Abnormality of glycine metabolism (HP:0010895)2.99529082
23Abnormality of serine family amino acid metabolism (HP:0010894)2.99529082
24Hypobetalipoproteinemia (HP:0003563)2.92568532
25Nephronophthisis (HP:0000090)2.91740350
26Recurrent bronchitis (HP:0002837)2.89406376
27Recurrent otitis media (HP:0000403)2.89096827
28Recurrent sinusitis (HP:0011108)2.86733316
29Abnormality of renal excretion (HP:0011036)2.76764598
30Nausea (HP:0002018)2.75687748
31Elevated erythrocyte sedimentation rate (HP:0003565)2.74194865
32Decreased circulating renin level (HP:0003351)2.69910078
33Abnormality of proline metabolism (HP:0010907)2.68794717
34Hydroxyprolinuria (HP:0003080)2.68794717
35Hepatic necrosis (HP:0002605)2.68545912
36Confusion (HP:0001289)2.66991081
37Agammaglobulinemia (HP:0004432)2.64224464
38Autoimmune hemolytic anemia (HP:0001890)2.61437994
39Cerebral palsy (HP:0100021)2.60356502
40Metabolic acidosis (HP:0001942)2.60253375
41Abnormality of aromatic amino acid family metabolism (HP:0004338)2.58322139
42Hyperammonemia (HP:0001987)2.57705671
43Abnormal urine output (HP:0012590)2.55104060
44Azoospermia (HP:0000027)2.52650256
45Generalized aminoaciduria (HP:0002909)2.51958070
46Thrombocytosis (HP:0001894)2.50826044
47Alkalosis (HP:0001948)2.50059208
48Petechiae (HP:0000967)2.49984313
49Widely patent fontanelles and sutures (HP:0004492)2.49879839
50Systemic lupus erythematosus (HP:0002725)2.45980609
51Gonadotropin excess (HP:0000837)2.45679155
52Lethargy (HP:0001254)2.44752514
53Hepatocellular necrosis (HP:0001404)2.44607992
54Abnormality of chloride homeostasis (HP:0011422)2.44419541
55Abnormality of aspartate family amino acid metabolism (HP:0010899)2.44145684
56Abnormality of the renal medulla (HP:0100957)2.39228899
57Cholecystitis (HP:0001082)2.39060269
58Abnormal gallbladder physiology (HP:0012438)2.39060269
59Impulsivity (HP:0100710)2.37625077
60Methylmalonic aciduria (HP:0012120)2.37270941
61Chronic diarrhea (HP:0002028)2.37268712
62Abnormal urine phosphate concentration (HP:0012599)2.36397471
63Megaloblastic anemia (HP:0001889)2.35650611
64Abnormality of magnesium homeostasis (HP:0004921)2.31848849
65Ketosis (HP:0001946)2.28016570
66Cupped ribs (HP:0000887)2.27655372
67Increased CSF protein (HP:0002922)2.27072269
68Abdominal distention (HP:0003270)2.22628104
69Panhypogammaglobulinemia (HP:0003139)2.20978796
70Hypothermia (HP:0002045)2.19090624
71Ketoacidosis (HP:0001993)2.18628930
72Tubular atrophy (HP:0000092)2.17573675
73Potter facies (HP:0002009)2.16742217
74Facial shape deformation (HP:0011334)2.16742217
75Glycosuria (HP:0003076)2.14886045
76Abnormality of urine glucose concentration (HP:0011016)2.14886045
77Hypoglycemic coma (HP:0001325)2.12931151
78Gout (HP:0001997)2.12595872
79Abnormality of fatty-acid metabolism (HP:0004359)2.11815274
80Mitochondrial inheritance (HP:0001427)2.10872651
81Abnormal drinking behavior (HP:0030082)2.09702589
82Polydipsia (HP:0001959)2.09702589
83Steatorrhea (HP:0002570)2.09588945
84Abnormality of renin-angiotensin system (HP:0000847)2.09320697
85Conjugated hyperbilirubinemia (HP:0002908)2.07461398
86Xanthomatosis (HP:0000991)2.07163609
87Vacuolated lymphocytes (HP:0001922)2.07095463
88Increased muscle lipid content (HP:0009058)2.03623193
89Poikilocytosis (HP:0004447)2.00968320
90Spastic tetraparesis (HP:0001285)2.00040765
91Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.4579187
92Absent/shortened dynein arms (HP:0200106)10.0518338
93Dynein arm defect of respiratory motile cilia (HP:0012255)10.0518338
94Abnormality of T cell physiology (HP:0011840)1.96905189
95Abnormal glucose tolerance (HP:0001952)1.94252030
96Tubulointerstitial nephritis (HP:0001970)1.94129676
97Hyperactive renin-angiotensin system (HP:0000841)1.94102619
98Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.92794913
99Decreased activity of mitochondrial respiratory chain (HP:0008972)1.92794913
100Tubulointerstitial abnormality (HP:0001969)1.92603595
101Increased intramyocellular lipid droplets (HP:0012240)1.91100170
102Abnormality of small intestinal villus morphology (HP:0011472)1.90815639
103Villous atrophy (HP:0011473)1.90815639
104Proximal tubulopathy (HP:0000114)1.89791950
105Abnormality of the vitamin B12 metabolism (HP:0004341)1.88992572
106Acute lymphatic leukemia (HP:0006721)1.88386137
107Vomiting (HP:0002013)1.88044092
108Skin rash (HP:0000988)1.87351726
109Hypotension (HP:0002615)1.87200298
110Hypophosphatemia (HP:0002148)1.87087685
111Abnormality of the prostate (HP:0008775)1.86991928
112Right ventricular cardiomyopathy (HP:0011663)1.86393790
113Abnormal delayed hypersensitivity skin test (HP:0002963)1.86238958
114Hyperglycinuria (HP:0003108)1.85806591
115Posterior subcapsular cataract (HP:0007787)1.85668545
116Hypercholesterolemia (HP:0003124)1.85156539
117Acute encephalopathy (HP:0006846)1.84792799
118Growth hormone excess (HP:0000845)1.83749803
119Polyuria (HP:0000103)1.83671379
120Pancreatitis (HP:0001733)1.83585881
121Irritability (HP:0000737)1.83296322
122Hypomagnesemia (HP:0002917)1.83211025
123Pigmentary retinal degeneration (HP:0001146)1.82914365
124Macrocytic anemia (HP:0001972)1.82521429
125Abnormality of purine metabolism (HP:0004352)1.82112194
126Delayed CNS myelination (HP:0002188)1.81711227
127Palpitations (HP:0001962)1.81610449
128Cerebral edema (HP:0002181)1.81389209
129Tubulointerstitial fibrosis (HP:0005576)1.80911921
130Hypoalbuminemia (HP:0003073)1.80209694
131Abnormal albumin level (HP:0012116)1.80209694
132B lymphocytopenia (HP:0010976)1.78073320
133Abnormality of B cell number (HP:0010975)1.78073320
134Dehydration (HP:0001944)1.77656144
135Chronic obstructive pulmonary disease (HP:0006510)1.75236344
136Obstructive lung disease (HP:0006536)1.75236344
137Increased CSF lactate (HP:0002490)1.75088718
138Abnormal mitochondria in muscle tissue (HP:0008316)1.74973427
139Fat malabsorption (HP:0002630)1.74176955
140Abnormality of vitamin B metabolism (HP:0004340)1.73092756
141Increased IgE level (HP:0003212)1.72216311
142Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.65688832
143Gastrointestinal dysmotility (HP:0002579)1.65595840
144Abnormality of the renal cortex (HP:0011035)1.61909075
145Congenital sensorineural hearing impairment (HP:0008527)1.61793883
146Flat acetabular roof (HP:0003180)1.61054013
147Metabolic alkalosis (HP:0200114)1.59070622
148Bundle branch block (HP:0011710)1.58154483
149Nephrolithiasis (HP:0000787)1.57982080
150Wide cranial sutures (HP:0010537)1.54820522
151Mesangial abnormality (HP:0001966)1.54561500
152Hyperphosphaturia (HP:0003109)1.53276631
153Severe combined immunodeficiency (HP:0004430)1.52023866
154Hypolipoproteinemia (HP:0010981)1.51952264
155Flattened epiphyses (HP:0003071)1.51826051
156Fatigue (HP:0012378)1.50646839
157Increased purine levels (HP:0004368)1.46604459
158Hyperuricemia (HP:0002149)1.46604459
159Stage 5 chronic kidney disease (HP:0003774)1.45691522
160Short femoral neck (HP:0100864)1.44532079
161Vascular calcification (HP:0004934)1.44385578
162Combined immunodeficiency (HP:0005387)1.39315223
163Rhabdomyolysis (HP:0003201)1.38843652
164Hemorrhage of the eye (HP:0011885)1.37352186
165Abnormality of midbrain morphology (HP:0002418)1.36311015
166Molar tooth sign on MRI (HP:0002419)1.36311015
167Abnormality of nucleobase metabolism (HP:0010932)1.35776511
168Dyschromatopsia (HP:0007641)1.34471325

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK46.82505019
2PDK36.82505019
3TESK15.84952043
4ACVR1B4.53644693
5PDK24.47005428
6PRKD33.58409895
7ICK3.53251418
8WNK42.93092627
9LMTK22.76780211
10FRK2.76208810
11BCKDK2.64165496
12FLT32.54645918
13VRK22.40672125
14MST1R2.36027743
15MST42.29879755
16STK392.17798517
17MAP4K22.05387849
18PRKG21.97370687
19DAPK21.84477512
20TNK21.84470590
21PTK2B1.62970917
22NEK21.59877848
23DYRK1B1.52026057
24GRK61.47978320
25ITK1.43390378
26MAP2K21.34558170
27KDR1.32491981
28MAP2K61.32249890
29SYK1.29910141
30STK381.25145996
31NME21.18838478
32BMPR21.18235296
33FES1.17282507
34SCYL21.16847530
35ADRBK21.16440520
36NLK1.11528376
37NME11.07716926
38TESK21.06913535
39MAP3K101.06167211
40PDK11.03930435
41TTK1.01788116
42MAPK151.01036278
43JAK30.99357873
44TRPM70.96999436
45DAPK10.96892448
46MAP4K10.96181093
47RIPK40.94841418
48RIPK10.94389664
49TAOK30.94344000
50CDK190.92887290
51INSRR0.90154215
52EIF2AK30.88960661
53ERN10.86212495
54PIK3CG0.84762669
55MAP3K120.84039765
56IKBKB0.83758544
57PTK60.82491997
58NUAK10.80722767
59RPS6KB20.80638862
60PHKG10.78296840
61PHKG20.78296840
62LYN0.77983586
63MAPKAPK30.77017487
64PASK0.76652915
65MAP2K30.76181822
66EEF2K0.74524343
67PAK40.69226669
68STK100.69153408
69TXK0.66952477
70PDPK10.66031315
71LCK0.65126840
72TBK10.64951451
73WNK10.64817609
74TNIK0.64220949
75TAOK10.62828465
76STK30.62181242
77MAPKAPK50.62019214
78MYLK0.60883038
79FER0.59847544
80FGFR30.59336251
81ZAK0.58801835
82HIPK20.56398844
83CCNB10.55082878
84PIM20.54072817
85MATK0.53954634
86MAP3K20.53393878
87VRK10.51991941
88EPHB20.51248192
89DYRK30.50226271
90MAP3K110.49733277
91MKNK10.49556549
92EPHA20.47476488
93ABL20.46360212
94PAK10.46176532
95TYRO30.43769419
96BMPR1B0.43606104
97STK160.40926658
98STK38L0.40432827
99CHEK20.38389999
100CAMK2D0.38019594
101EPHA30.37626108
102ZAP700.36875524
103PRKACG0.36677373
104STK240.36104720
105TAF10.35953162
106OXSR10.35304746
107WNK30.35169585
108IRAK40.34523043
109MAP3K10.34445956
110MET0.34373305
111TLK10.34357958
112PNCK0.34184650
113IRAK10.33080029
114RPS6KA50.33074011
115PRKCE0.31394805
116BRSK20.30972794
117CSNK1A10.30103610
118PRKCI0.29388170
119PRKAA10.28784476
120MAPK30.28588109
121EPHB10.27134890
122PBK0.26650044
123MUSK0.26480302
124WEE10.25621096
125BTK0.25488828
126PRKAA20.25371660
127MAP3K30.24627397
128MAP3K80.23406207
129CSK0.23269564
130BRAF0.23163087
131AURKB0.21844511
132PIK3CA0.17597688
133PIM10.17461138
134PAK20.17313816
135PRKCD0.16462706
136TYK20.16371677
137MAPK110.14753332
138TEC0.14716815
139MAP3K70.14592377
140PRKCQ0.14183178
141PTK20.13666631
142CHEK10.11875192
143ATR0.11469817
144AKT30.11243924
145IKBKE0.10393252
146PINK10.10035027
147RPS6KB10.09434208
148BLK0.08523200
149PRKCA0.08457472
150GRK10.08364626
151ERBB20.07845565
152KIT0.07476347
153CSF1R0.06871144
154LRRK20.06292775

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049755.24936076
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.44049617
3Mineral absorption_Homo sapiens_hsa049783.66773323
4Renin-angiotensin system_Homo sapiens_hsa046143.65833876
5Vitamin digestion and absorption_Homo sapiens_hsa049773.36353909
6Carbohydrate digestion and absorption_Homo sapiens_hsa049732.96036106
7Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.62619679
8Fructose and mannose metabolism_Homo sapiens_hsa000512.49243103
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.39631003
10Pyruvate metabolism_Homo sapiens_hsa006202.39075489
11Sulfur metabolism_Homo sapiens_hsa009202.25205805
12Galactose metabolism_Homo sapiens_hsa000522.14581293
13Protein digestion and absorption_Homo sapiens_hsa049742.05440542
14Asthma_Homo sapiens_hsa053102.00054618
15Glycerolipid metabolism_Homo sapiens_hsa005611.99276385
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.95716218
17Caffeine metabolism_Homo sapiens_hsa002321.94483488
18Starch and sucrose metabolism_Homo sapiens_hsa005001.78350745
19Glutathione metabolism_Homo sapiens_hsa004801.78292783
20Pentose phosphate pathway_Homo sapiens_hsa000301.76004285
21Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.68841052
22Linoleic acid metabolism_Homo sapiens_hsa005911.67713690
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.66493985
24Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.63789737
25Folate biosynthesis_Homo sapiens_hsa007901.62941509
26PPAR signaling pathway_Homo sapiens_hsa033201.61575616
27Type I diabetes mellitus_Homo sapiens_hsa049401.60802466
28Pentose and glucuronate interconversions_Homo sapiens_hsa000401.60648951
29Bile secretion_Homo sapiens_hsa049761.59129235
30Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.54963168
31Fatty acid degradation_Homo sapiens_hsa000711.54775194
32Fatty acid biosynthesis_Homo sapiens_hsa000611.52685867
33Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.47072393
34Cyanoamino acid metabolism_Homo sapiens_hsa004601.42923873
35Propanoate metabolism_Homo sapiens_hsa006401.40351491
36Histidine metabolism_Homo sapiens_hsa003401.33705657
37Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.33206191
38Allograft rejection_Homo sapiens_hsa053301.30620096
39Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.29270380
40Carbon metabolism_Homo sapiens_hsa012001.25774697
41Selenocompound metabolism_Homo sapiens_hsa004501.23304958
42Autoimmune thyroid disease_Homo sapiens_hsa053201.13975939
43Sphingolipid metabolism_Homo sapiens_hsa006001.13469427
44Glycerophospholipid metabolism_Homo sapiens_hsa005641.10453695
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.10428854
46Graft-versus-host disease_Homo sapiens_hsa053321.05550495
47Arachidonic acid metabolism_Homo sapiens_hsa005901.05293506
48Fatty acid elongation_Homo sapiens_hsa000620.94937671
49Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.93574689
50Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.90266858
51ABC transporters_Homo sapiens_hsa020100.87141945
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.85882842
53Tryptophan metabolism_Homo sapiens_hsa003800.81286954
54Chemical carcinogenesis_Homo sapiens_hsa052040.80892270
55Staphylococcus aureus infection_Homo sapiens_hsa051500.78137202
56Fatty acid metabolism_Homo sapiens_hsa012120.76340164
57Phenylalanine metabolism_Homo sapiens_hsa003600.75689669
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74981421
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73976288
60Vitamin B6 metabolism_Homo sapiens_hsa007500.72436076
61Huntingtons disease_Homo sapiens_hsa050160.71125527
62Thyroid hormone synthesis_Homo sapiens_hsa049180.70380886
63Tyrosine metabolism_Homo sapiens_hsa003500.70249250
64Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.69180262
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67976096
66Pancreatic secretion_Homo sapiens_hsa049720.67501236
67Ether lipid metabolism_Homo sapiens_hsa005650.66260853
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65054719
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.64152594
70Biosynthesis of amino acids_Homo sapiens_hsa012300.64069285
71Arginine and proline metabolism_Homo sapiens_hsa003300.62871542
72Glucagon signaling pathway_Homo sapiens_hsa049220.62496009
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.59565416
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53421432
75Metabolic pathways_Homo sapiens_hsa011000.52607945
76Purine metabolism_Homo sapiens_hsa002300.51869674
77Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.51534404
78Legionellosis_Homo sapiens_hsa051340.51092032
79Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.50665704
80Leishmaniasis_Homo sapiens_hsa051400.48336156
81Dorso-ventral axis formation_Homo sapiens_hsa043200.47951828
82Retinol metabolism_Homo sapiens_hsa008300.47899213
83Peroxisome_Homo sapiens_hsa041460.47387043
84Drug metabolism - other enzymes_Homo sapiens_hsa009830.47129626
85Antigen processing and presentation_Homo sapiens_hsa046120.46229398
86Ribosome_Homo sapiens_hsa030100.45777377
87Other glycan degradation_Homo sapiens_hsa005110.45639831
88Insulin secretion_Homo sapiens_hsa049110.43867031
89Base excision repair_Homo sapiens_hsa034100.41803914
90Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.41709304
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.41290436
92Intestinal immune network for IgA production_Homo sapiens_hsa046720.40492090
93Hematopoietic cell lineage_Homo sapiens_hsa046400.39804217
94N-Glycan biosynthesis_Homo sapiens_hsa005100.39556923
95Salmonella infection_Homo sapiens_hsa051320.36300804
96Basal transcription factors_Homo sapiens_hsa030220.34711679
97beta-Alanine metabolism_Homo sapiens_hsa004100.32550660
98Cardiac muscle contraction_Homo sapiens_hsa042600.31659222
99Glycosaminoglycan degradation_Homo sapiens_hsa005310.26493040
1002-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.23500793
101Rheumatoid arthritis_Homo sapiens_hsa053230.23142499
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.21725318
103Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.21537128
104Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.20725953
105Renin secretion_Homo sapiens_hsa049240.20658533
106Influenza A_Homo sapiens_hsa051640.20613185
107Gastric acid secretion_Homo sapiens_hsa049710.19705042
108Oxidative phosphorylation_Homo sapiens_hsa001900.18511226
109Tight junction_Homo sapiens_hsa045300.17462450
110Alzheimers disease_Homo sapiens_hsa050100.17441700
111Parkinsons disease_Homo sapiens_hsa050120.16228228
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.16116272
113Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.15846038
114African trypanosomiasis_Homo sapiens_hsa051430.15248029
115Pyrimidine metabolism_Homo sapiens_hsa002400.14915580
116Arginine biosynthesis_Homo sapiens_hsa002200.14533960
117Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.13211822
118Fanconi anemia pathway_Homo sapiens_hsa034600.09734187
119Inositol phosphate metabolism_Homo sapiens_hsa005620.08840605
120VEGF signaling pathway_Homo sapiens_hsa043700.07396048
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.07222604
122Adipocytokine signaling pathway_Homo sapiens_hsa049200.06908157
123Steroid hormone biosynthesis_Homo sapiens_hsa001400.06540664
124Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.04437475
125Butanoate metabolism_Homo sapiens_hsa006500.03579002
126Sulfur relay system_Homo sapiens_hsa041220.03171768
127Primary immunodeficiency_Homo sapiens_hsa053400.02406202

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