

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sphingosine metabolic process (GO:0006670) | 6.13814935 |
| 2 | protein neddylation (GO:0045116) | 5.79028355 |
| 3 | diol metabolic process (GO:0034311) | 5.73794265 |
| 4 | sphingoid metabolic process (GO:0046519) | 5.42239340 |
| 5 | DNA methylation involved in gamete generation (GO:0043046) | 5.36141906 |
| 6 | thrombin receptor signaling pathway (GO:0070493) | 4.95773571 |
| 7 | centriole replication (GO:0007099) | 4.78544243 |
| 8 | regulation of meiosis I (GO:0060631) | 4.72361182 |
| 9 | meiotic chromosome segregation (GO:0045132) | 4.61004182 |
| 10 | regulation of protein glycosylation (GO:0060049) | 4.32884194 |
| 11 | neutrophil activation involved in immune response (GO:0002283) | 4.05902445 |
| 12 | microtubule depolymerization (GO:0007019) | 4.00545855 |
| 13 | piRNA metabolic process (GO:0034587) | 3.99173569 |
| 14 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.69704675 |
| 15 | DNA deamination (GO:0045006) | 3.67799071 |
| 16 | protein-chromophore linkage (GO:0018298) | 3.65798354 |
| 17 | amine catabolic process (GO:0009310) | 3.64378532 |
| 18 | cellular biogenic amine catabolic process (GO:0042402) | 3.64378532 |
| 19 | DNA double-strand break processing (GO:0000729) | 3.63085463 |
| 20 | L-phenylalanine catabolic process (GO:0006559) | 3.63076217 |
| 21 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.63076217 |
| 22 | negative regulation of heart rate (GO:0010459) | 3.53422453 |
| 23 | sulfate transmembrane transport (GO:1902358) | 3.52656000 |
| 24 | regulation of platelet activation (GO:0010543) | 3.52032925 |
| 25 | regulation of platelet aggregation (GO:0090330) | 3.51875063 |
| 26 | positive regulation of mast cell activation (GO:0033005) | 3.51597833 |
| 27 | tyrosine metabolic process (GO:0006570) | 3.50998447 |
| 28 | positive regulation of developmental pigmentation (GO:0048087) | 3.49002461 |
| 29 | tachykinin receptor signaling pathway (GO:0007217) | 3.42557937 |
| 30 | indolalkylamine metabolic process (GO:0006586) | 3.42336067 |
| 31 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.37849859 |
| 32 | regulation of pigment cell differentiation (GO:0050932) | 3.30677872 |
| 33 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.30214332 |
| 34 | centriole assembly (GO:0098534) | 3.28335963 |
| 35 | sulfate transport (GO:0008272) | 3.27328106 |
| 36 | aromatic amino acid family catabolic process (GO:0009074) | 3.23316541 |
| 37 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 3.20789848 |
| 38 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.20340193 |
| 39 | blood coagulation, intrinsic pathway (GO:0007597) | 3.19517844 |
| 40 | rhodopsin mediated signaling pathway (GO:0016056) | 3.19192863 |
| 41 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.15163316 |
| 42 | lipopolysaccharide biosynthetic process (GO:0009103) | 3.13656919 |
| 43 | regulation of memory T cell differentiation (GO:0043380) | 3.10105243 |
| 44 | male meiosis (GO:0007140) | 3.09136003 |
| 45 | regulation of lipoprotein metabolic process (GO:0050746) | 3.08530956 |
| 46 | autophagic vacuole fusion (GO:0000046) | 3.06245117 |
| 47 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.05288782 |
| 48 | negative regulation of stress fiber assembly (GO:0051497) | 3.03552252 |
| 49 | negative regulation of norepinephrine secretion (GO:0010700) | 3.01657315 |
| 50 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 3.00194850 |
| 51 | positive regulation of T cell cytokine production (GO:0002726) | 2.97862777 |
| 52 | negative regulation of response to food (GO:0032096) | 2.91565722 |
| 53 | negative regulation of appetite (GO:0032099) | 2.91565722 |
| 54 | fatty acid elongation (GO:0030497) | 2.91098947 |
| 55 | sulfation (GO:0051923) | 2.88887417 |
| 56 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.88403528 |
| 57 | indole-containing compound catabolic process (GO:0042436) | 2.87974607 |
| 58 | indolalkylamine catabolic process (GO:0046218) | 2.87974607 |
| 59 | tryptophan catabolic process (GO:0006569) | 2.87974607 |
| 60 | negative regulation of platelet activation (GO:0010544) | 2.85847832 |
| 61 | glycerophospholipid catabolic process (GO:0046475) | 2.83299794 |
| 62 | platelet aggregation (GO:0070527) | 2.83125408 |
| 63 | lipopolysaccharide metabolic process (GO:0008653) | 2.82882772 |
| 64 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.82320869 |
| 65 | tryptophan metabolic process (GO:0006568) | 2.82095513 |
| 66 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.79483312 |
| 67 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.79198094 |
| 68 | mast cell activation involved in immune response (GO:0002279) | 2.78131253 |
| 69 | mast cell degranulation (GO:0043303) | 2.78131253 |
| 70 | reciprocal DNA recombination (GO:0035825) | 2.77256201 |
| 71 | reciprocal meiotic recombination (GO:0007131) | 2.77256201 |
| 72 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.76879796 |
| 73 | L-phenylalanine metabolic process (GO:0006558) | 2.76879796 |
| 74 | platelet dense granule organization (GO:0060155) | 2.76082688 |
| 75 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.74661318 |
| 76 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.74368285 |
| 77 | aromatic amino acid family metabolic process (GO:0009072) | 2.73767386 |
| 78 | low-density lipoprotein particle remodeling (GO:0034374) | 2.72152974 |
| 79 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.72073588 |
| 80 | double-strand break repair via homologous recombination (GO:0000724) | 2.71932436 |
| 81 | recombinational repair (GO:0000725) | 2.71437061 |
| 82 | organelle membrane fusion (GO:0090174) | 2.71101490 |
| 83 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 2.69064181 |
| 84 | adenosine metabolic process (GO:0046085) | 2.68955842 |
| 85 | serotonin receptor signaling pathway (GO:0007210) | 2.68345867 |
| 86 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.68135593 |
| 87 | positive regulation of protein homodimerization activity (GO:0090073) | 2.66721869 |
| 88 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 2.64701310 |
| 89 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.61502578 |
| 90 | negative regulation of neural precursor cell proliferation (GO:2000178) | 2.61272712 |
| 91 | negative regulation of protein localization to cell surface (GO:2000009) | 2.60772904 |
| 92 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.59999322 |
| 93 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.58942143 |
| 94 | negative regulation of cell cycle G2/M phase transition (GO:1902750) | 2.58911739 |
| 95 | adaptation of signaling pathway (GO:0023058) | 2.57474518 |
| 96 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.57469238 |
| 97 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.56912422 |
| 98 | microtubule polymerization or depolymerization (GO:0031109) | 2.56829663 |
| 99 | regulation of triglyceride catabolic process (GO:0010896) | 2.56611479 |
| 100 | methionine biosynthetic process (GO:0009086) | 2.55814238 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.67257766 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.40151958 |
| 3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.10618309 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.87393278 |
| 5 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.50301569 |
| 6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.47738312 |
| 7 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.33578112 |
| 8 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.31096302 |
| 9 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.17041368 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.15935962 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.09608369 |
| 12 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.04453183 |
| 13 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.93621563 |
| 14 | EWS_26573619_Chip-Seq_HEK293_Human | 1.91391737 |
| 15 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.91028406 |
| 16 | P300_19829295_ChIP-Seq_ESCs_Human | 1.88742566 |
| 17 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.77145971 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.75782277 |
| 19 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.72097442 |
| 20 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.71995766 |
| 21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.71142481 |
| 22 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.70693991 |
| 23 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.60097031 |
| 24 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.60097031 |
| 25 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.57502507 |
| 26 | STAT3_23295773_ChIP-Seq_U87_Human | 1.55623113 |
| 27 | TCF4_23295773_ChIP-Seq_U87_Human | 1.53105654 |
| 28 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.53040420 |
| 29 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.51469649 |
| 30 | GATA1_19941826_ChIP-Seq_K562_Human | 1.50963300 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.50321659 |
| 32 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.49842701 |
| 33 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.49782232 |
| 34 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.48520043 |
| 35 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.48435072 |
| 36 | GATA2_19941826_ChIP-Seq_K562_Human | 1.46586720 |
| 37 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.43766998 |
| 38 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.43418859 |
| 39 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.41478778 |
| 40 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.41307761 |
| 41 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.41307761 |
| 42 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.41132143 |
| 43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.38576139 |
| 44 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.37612208 |
| 45 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.36767714 |
| 46 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36094755 |
| 47 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.34117969 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.33977644 |
| 49 | AR_25329375_ChIP-Seq_VCAP_Human | 1.33638825 |
| 50 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.33259975 |
| 51 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30628287 |
| 52 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.28807678 |
| 53 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.26300692 |
| 54 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.25804783 |
| 55 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.24752633 |
| 56 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.23858492 |
| 57 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.23840268 |
| 58 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.22523931 |
| 59 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.21076798 |
| 60 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.20769991 |
| 61 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20166542 |
| 62 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.20119867 |
| 63 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.18321550 |
| 64 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.18021441 |
| 65 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.17731904 |
| 66 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.17526438 |
| 67 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.15657738 |
| 68 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.15464501 |
| 69 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.14639785 |
| 70 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.14043968 |
| 71 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.13476388 |
| 72 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.11891985 |
| 73 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.11525039 |
| 74 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.11425999 |
| 75 | AR_20517297_ChIP-Seq_VCAP_Human | 1.11230762 |
| 76 | GATA1_22025678_ChIP-Seq_K562_Human | 1.10993642 |
| 77 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.10457075 |
| 78 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.09160260 |
| 79 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.08293889 |
| 80 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.07373890 |
| 81 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.07373890 |
| 82 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.06701339 |
| 83 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.06258785 |
| 84 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.05662162 |
| 85 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.05628483 |
| 86 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05534165 |
| 87 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.05387221 |
| 88 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04959982 |
| 89 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.04959982 |
| 90 | CEBPB_22108803_ChIP-Seq_LS180_Human | 1.02449410 |
| 91 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.02207094 |
| 92 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.02188605 |
| 93 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01366359 |
| 94 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.01195073 |
| 95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.01159505 |
| 96 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.00723086 |
| 97 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.99595174 |
| 98 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.99379785 |
| 99 | NFYA_21822215_ChIP-Seq_K562_Human | 0.99277907 |
| 100 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98808660 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005464_abnormal_platelet_physiology | 5.29582080 |
| 2 | MP0002837_dystrophic_cardiac_calcinosis | 4.51715783 |
| 3 | MP0003136_yellow_coat_color | 4.46490562 |
| 4 | MP0005171_absent_coat_pigmentation | 3.96082565 |
| 5 | MP0004147_increased_porphyrin_level | 3.62141898 |
| 6 | MP0002653_abnormal_ependyma_morphology | 3.36799103 |
| 7 | MP0008004_abnormal_stomach_pH | 2.49549146 |
| 8 | MP0003045_fibrosis | 2.38361528 |
| 9 | MP0000569_abnormal_digit_pigmentation | 2.27291501 |
| 10 | MP0005410_abnormal_fertilization | 2.20527522 |
| 11 | MP0002736_abnormal_nociception_after | 2.15255469 |
| 12 | MP0003890_abnormal_embryonic-extraembry | 2.14162393 |
| 13 | MP0003646_muscle_fatigue | 2.08456654 |
| 14 | MP0005670_abnormal_white_adipose | 2.04051194 |
| 15 | MP0008872_abnormal_physiological_respon | 1.99165834 |
| 16 | MP0005646_abnormal_pituitary_gland | 1.92251611 |
| 17 | MP0002102_abnormal_ear_morphology | 1.87180120 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.81514767 |
| 19 | MP0005085_abnormal_gallbladder_physiolo | 1.78059643 |
| 20 | MP0005083_abnormal_biliary_tract | 1.74356818 |
| 21 | MP0003724_increased_susceptibility_to | 1.72352431 |
| 22 | MP0003195_calcinosis | 1.67297483 |
| 23 | MP0003879_abnormal_hair_cell | 1.65979791 |
| 24 | MP0003718_maternal_effect | 1.65186167 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.62814349 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.60782538 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.57065417 |
| 28 | MP0000465_gastrointestinal_hemorrhage | 1.56154134 |
| 29 | MP0005084_abnormal_gallbladder_morpholo | 1.51349366 |
| 30 | MP0008057_abnormal_DNA_replication | 1.48568280 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.45522629 |
| 32 | MP0008775_abnormal_heart_ventricle | 1.44597394 |
| 33 | MP0000230_abnormal_systemic_arterial | 1.43081461 |
| 34 | MP0005365_abnormal_bile_salt | 1.39727848 |
| 35 | MP0006276_abnormal_autonomic_nervous | 1.37486124 |
| 36 | MP0002138_abnormal_hepatobiliary_system | 1.31840929 |
| 37 | MP0003656_abnormal_erythrocyte_physiolo | 1.31276172 |
| 38 | MP0002938_white_spotting | 1.29733417 |
| 39 | MP0002095_abnormal_skin_pigmentation | 1.29214806 |
| 40 | MP0008875_abnormal_xenobiotic_pharmacok | 1.28471887 |
| 41 | MP0004381_abnormal_hair_follicle | 1.26242438 |
| 42 | MP0008058_abnormal_DNA_repair | 1.26197987 |
| 43 | MP0006054_spinal_hemorrhage | 1.26002695 |
| 44 | MP0004084_abnormal_cardiac_muscle | 1.25670799 |
| 45 | MP0005174_abnormal_tail_pigmentation | 1.22269539 |
| 46 | MP0004142_abnormal_muscle_tone | 1.14343583 |
| 47 | MP0003252_abnormal_bile_duct | 1.13098362 |
| 48 | MP0005167_abnormal_blood-brain_barrier | 1.12669991 |
| 49 | MP0009046_muscle_twitch | 1.11504539 |
| 50 | MP0004043_abnormal_pH_regulation | 1.09929521 |
| 51 | MP0000015_abnormal_ear_pigmentation | 1.09744904 |
| 52 | MP0010329_abnormal_lipoprotein_level | 1.08978083 |
| 53 | MP0002733_abnormal_thermal_nociception | 1.07322750 |
| 54 | MP0006036_abnormal_mitochondrial_physio | 1.07288210 |
| 55 | MP0002735_abnormal_chemical_nociception | 1.05239402 |
| 56 | MP0001501_abnormal_sleep_pattern | 1.03442093 |
| 57 | MP0002132_abnormal_respiratory_system | 1.01938115 |
| 58 | MP0001984_abnormal_olfaction | 1.00686958 |
| 59 | MP0004215_abnormal_myocardial_fiber | 1.00201811 |
| 60 | MP0005395_other_phenotype | 0.99854099 |
| 61 | MP0001929_abnormal_gametogenesis | 0.97954936 |
| 62 | MP0002876_abnormal_thyroid_physiology | 0.97538068 |
| 63 | MP0010094_abnormal_chromosome_stability | 0.96501749 |
| 64 | MP0003698_abnormal_male_reproductive | 0.95071962 |
| 65 | MP0001835_abnormal_antigen_presentation | 0.94632850 |
| 66 | MP0001970_abnormal_pain_threshold | 0.93520877 |
| 67 | MP0009764_decreased_sensitivity_to | 0.92767766 |
| 68 | MP0003137_abnormal_impulse_conducting | 0.92426242 |
| 69 | MP0005253_abnormal_eye_physiology | 0.92214231 |
| 70 | MP0002210_abnormal_sex_determination | 0.85962600 |
| 71 | MP0006035_abnormal_mitochondrial_morpho | 0.84787457 |
| 72 | MP0003638_abnormal_response/metabolism_ | 0.82459793 |
| 73 | MP0002148_abnormal_hypersensitivity_rea | 0.82357735 |
| 74 | MP0002272_abnormal_nervous_system | 0.80628478 |
| 75 | MP0002398_abnormal_bone_marrow | 0.79873435 |
| 76 | MP0005397_hematopoietic_system_phenotyp | 0.79116817 |
| 77 | MP0001545_abnormal_hematopoietic_system | 0.79116817 |
| 78 | MP0005389_reproductive_system_phenotype | 0.78242015 |
| 79 | MP0001661_extended_life_span | 0.78071930 |
| 80 | MP0009697_abnormal_copulation | 0.78058743 |
| 81 | MP0000383_abnormal_hair_follicle | 0.77840517 |
| 82 | MP0000427_abnormal_hair_cycle | 0.77694264 |
| 83 | MP0002160_abnormal_reproductive_system | 0.76616770 |
| 84 | MP0006292_abnormal_olfactory_placode | 0.76542636 |
| 85 | MP0000689_abnormal_spleen_morphology | 0.75742198 |
| 86 | MP0000653_abnormal_sex_gland | 0.73434166 |
| 87 | MP0002168_other_aberrant_phenotype | 0.71817938 |
| 88 | MP0004130_abnormal_muscle_cell | 0.71472049 |
| 89 | MP0009765_abnormal_xenobiotic_induced | 0.71035764 |
| 90 | MP0009763_increased_sensitivity_to | 0.70705448 |
| 91 | MP0004036_abnormal_muscle_relaxation | 0.68534389 |
| 92 | MP0004085_abnormal_heartbeat | 0.67559398 |
| 93 | MP0008995_early_reproductive_senescence | 0.66708781 |
| 94 | MP0001145_abnormal_male_reproductive | 0.65723925 |
| 95 | MP0005535_abnormal_body_temperature | 0.64795112 |
| 96 | MP0001764_abnormal_homeostasis | 0.64763798 |
| 97 | MP0005671_abnormal_response_to | 0.62343092 |
| 98 | MP0001800_abnormal_humoral_immune | 0.61789328 |
| 99 | MP0003186_abnormal_redox_activity | 0.60841973 |
| 100 | MP0002118_abnormal_lipid_homeostasis | 0.60641974 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Prolonged bleeding time (HP:0003010) | 6.42661679 |
| 2 | Petechiae (HP:0000967) | 6.21797144 |
| 3 | Menorrhagia (HP:0000132) | 5.36790834 |
| 4 | Increased mean platelet volume (HP:0011877) | 5.20920604 |
| 5 | Acanthocytosis (HP:0001927) | 5.07448169 |
| 6 | Purpura (HP:0000979) | 4.83767375 |
| 7 | Abnormal platelet volume (HP:0011876) | 4.79212652 |
| 8 | Poikilocytosis (HP:0004447) | 4.42041991 |
| 9 | Epistaxis (HP:0000421) | 4.28470971 |
| 10 | Amelogenesis imperfecta (HP:0000705) | 3.53588224 |
| 11 | Spontaneous hematomas (HP:0007420) | 3.53336874 |
| 12 | Pancreatic cysts (HP:0001737) | 3.40769358 |
| 13 | Gingival bleeding (HP:0000225) | 3.33265324 |
| 14 | Hyperlipoproteinemia (HP:0010980) | 3.13031774 |
| 15 | Focal motor seizures (HP:0011153) | 3.07890841 |
| 16 | Impaired platelet aggregation (HP:0003540) | 3.03079420 |
| 17 | Abnormal platelet function (HP:0011869) | 3.03079420 |
| 18 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.02801424 |
| 19 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.01632547 |
| 20 | Type II lissencephaly (HP:0007260) | 2.99835018 |
| 21 | Abnormality of the renal cortex (HP:0011035) | 2.91337971 |
| 22 | Pancreatic fibrosis (HP:0100732) | 2.78066203 |
| 23 | 3-Methylglutaconic aciduria (HP:0003535) | 2.77030156 |
| 24 | Conjunctival telangiectasia (HP:0000524) | 2.73403370 |
| 25 | Dyschromatopsia (HP:0007641) | 2.72429241 |
| 26 | Hyperthyroidism (HP:0000836) | 2.68163553 |
| 27 | Aplastic anemia (HP:0001915) | 2.67357259 |
| 28 | Decreased central vision (HP:0007663) | 2.54008658 |
| 29 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.53422421 |
| 30 | Abnormality of DNA repair (HP:0003254) | 2.47575773 |
| 31 | Congenital stationary night blindness (HP:0007642) | 2.41880989 |
| 32 | Hypoplastic iliac wings (HP:0002866) | 2.40984818 |
| 33 | Attenuation of retinal blood vessels (HP:0007843) | 2.39900624 |
| 34 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.38977177 |
| 35 | Abnormality of the renal medulla (HP:0100957) | 2.34166877 |
| 36 | Abnormal pupillary function (HP:0007686) | 2.27413531 |
| 37 | Tinnitus (HP:0000360) | 2.22665304 |
| 38 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.20820491 |
| 39 | Pendular nystagmus (HP:0012043) | 2.19674450 |
| 40 | Chromsome breakage (HP:0040012) | 2.18928997 |
| 41 | Ileus (HP:0002595) | 2.17000822 |
| 42 | Nephronophthisis (HP:0000090) | 2.15869652 |
| 43 | Parakeratosis (HP:0001036) | 2.14527660 |
| 44 | Ectopic kidney (HP:0000086) | 2.10681738 |
| 45 | True hermaphroditism (HP:0010459) | 2.10298941 |
| 46 | Duplicated collecting system (HP:0000081) | 2.09391136 |
| 47 | Abnormality of lateral ventricle (HP:0030047) | 2.08923825 |
| 48 | Pancytopenia (HP:0001876) | 2.00713222 |
| 49 | Renal cortical cysts (HP:0000803) | 2.00680175 |
| 50 | Autoimmune hemolytic anemia (HP:0001890) | 2.00578706 |
| 51 | Lissencephaly (HP:0001339) | 1.97701014 |
| 52 | Albinism (HP:0001022) | 1.97295189 |
| 53 | Abnormality of the renal collecting system (HP:0004742) | 1.96897984 |
| 54 | Dialeptic seizures (HP:0011146) | 1.96445103 |
| 55 | Abnormality of alanine metabolism (HP:0010916) | 1.96340347 |
| 56 | Hyperalaninemia (HP:0003348) | 1.96340347 |
| 57 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.96340347 |
| 58 | Abnormal auditory evoked potentials (HP:0006958) | 1.94859253 |
| 59 | Abolished electroretinogram (ERG) (HP:0000550) | 1.93731341 |
| 60 | Thyroid-stimulating hormone excess (HP:0002925) | 1.92770777 |
| 61 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.91358814 |
| 62 | Bruising susceptibility (HP:0000978) | 1.89429514 |
| 63 | Birth length less than 3rd percentile (HP:0003561) | 1.85361598 |
| 64 | Truncus arteriosus (HP:0001660) | 1.84776995 |
| 65 | Abnormality of chromosome stability (HP:0003220) | 1.84104820 |
| 66 | Upper limb muscle weakness (HP:0003484) | 1.82522266 |
| 67 | Gaze-evoked nystagmus (HP:0000640) | 1.81083108 |
| 68 | Cerebellar dysplasia (HP:0007033) | 1.79622087 |
| 69 | Colon cancer (HP:0003003) | 1.77697536 |
| 70 | Abnormality of midbrain morphology (HP:0002418) | 1.76735538 |
| 71 | Molar tooth sign on MRI (HP:0002419) | 1.76735538 |
| 72 | Stomatitis (HP:0010280) | 1.75986273 |
| 73 | Enlarged kidneys (HP:0000105) | 1.71905718 |
| 74 | Generalized aminoaciduria (HP:0002909) | 1.69113466 |
| 75 | Meckel diverticulum (HP:0002245) | 1.68114545 |
| 76 | Paralysis (HP:0003470) | 1.67748032 |
| 77 | Central scotoma (HP:0000603) | 1.67475709 |
| 78 | Cystic liver disease (HP:0006706) | 1.67058269 |
| 79 | Hematochezia (HP:0002573) | 1.66838236 |
| 80 | Polydipsia (HP:0001959) | 1.64153798 |
| 81 | Abnormal drinking behavior (HP:0030082) | 1.64153798 |
| 82 | Abnormality of the ileum (HP:0001549) | 1.63973454 |
| 83 | Biliary tract neoplasm (HP:0100574) | 1.62821642 |
| 84 | Hyperventilation (HP:0002883) | 1.61976718 |
| 85 | Difficulty walking (HP:0002355) | 1.59509961 |
| 86 | Febrile seizures (HP:0002373) | 1.59079250 |
| 87 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.58775410 |
| 88 | Clubbing of toes (HP:0100760) | 1.58661866 |
| 89 | Neoplasm of the small intestine (HP:0100833) | 1.57685832 |
| 90 | Portal hypertension (HP:0001409) | 1.57378124 |
| 91 | Abnormal ciliary motility (HP:0012262) | 1.57004026 |
| 92 | Hypomagnesemia (HP:0002917) | 1.56767324 |
| 93 | Hypoplasia of the pons (HP:0012110) | 1.56215965 |
| 94 | IgG deficiency (HP:0004315) | 1.56203453 |
| 95 | Methylmalonic aciduria (HP:0012120) | 1.55391184 |
| 96 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.55100342 |
| 97 | Pachygyria (HP:0001302) | 1.54487592 |
| 98 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.54139882 |
| 99 | Absent/shortened dynein arms (HP:0200106) | 1.54139882 |
| 100 | Abnormality of homocysteine metabolism (HP:0010919) | 1.52472748 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | LATS1 | 4.45629315 |
| 2 | FRK | 4.17952761 |
| 3 | STK38L | 3.82184970 |
| 4 | MST4 | 3.44719999 |
| 5 | BMPR1B | 2.96283889 |
| 6 | TAOK3 | 2.80333055 |
| 7 | RIPK4 | 2.50457556 |
| 8 | ZAK | 2.47321088 |
| 9 | ACVR1B | 2.46827664 |
| 10 | STK3 | 2.42040807 |
| 11 | EIF2AK1 | 2.38522960 |
| 12 | PIK3CG | 2.34455066 |
| 13 | TEC | 2.28543322 |
| 14 | ADRBK2 | 2.23254990 |
| 15 | BMX | 1.76545902 |
| 16 | TXK | 1.74148228 |
| 17 | NUAK1 | 1.71595341 |
| 18 | TNIK | 1.66446089 |
| 19 | LATS2 | 1.66166149 |
| 20 | NLK | 1.62844972 |
| 21 | PTK2B | 1.58213765 |
| 22 | MAP4K2 | 1.53714096 |
| 23 | MAPK13 | 1.49012849 |
| 24 | BTK | 1.43517128 |
| 25 | MYLK | 1.35145300 |
| 26 | TRIM28 | 1.33032438 |
| 27 | GRK5 | 1.27082953 |
| 28 | BMPR2 | 1.18449705 |
| 29 | PLK2 | 1.16747873 |
| 30 | WNK3 | 1.13006385 |
| 31 | MAP3K2 | 1.11047181 |
| 32 | MAP2K2 | 1.09154161 |
| 33 | DAPK2 | 1.08826609 |
| 34 | BRSK2 | 1.07008840 |
| 35 | STK38 | 1.04600191 |
| 36 | ADRBK1 | 1.02156398 |
| 37 | GRK1 | 1.00403717 |
| 38 | MAPKAPK3 | 0.99707759 |
| 39 | SYK | 0.98854257 |
| 40 | MAP3K4 | 0.96039878 |
| 41 | TAF1 | 0.90940615 |
| 42 | TNK2 | 0.86147973 |
| 43 | TGFBR1 | 0.85585126 |
| 44 | NTRK3 | 0.81769626 |
| 45 | WNK4 | 0.80518731 |
| 46 | FER | 0.76984909 |
| 47 | OXSR1 | 0.75259011 |
| 48 | INSRR | 0.75199268 |
| 49 | IKBKB | 0.74712062 |
| 50 | ERBB3 | 0.68896077 |
| 51 | LMTK2 | 0.68782731 |
| 52 | NEK2 | 0.66228232 |
| 53 | ITK | 0.66136433 |
| 54 | GRK6 | 0.65861550 |
| 55 | PINK1 | 0.62572999 |
| 56 | CSF1R | 0.62378416 |
| 57 | STK39 | 0.62135148 |
| 58 | MAP2K1 | 0.60251436 |
| 59 | PLK4 | 0.58458728 |
| 60 | PLK3 | 0.58067614 |
| 61 | MELK | 0.57754630 |
| 62 | DYRK2 | 0.54716514 |
| 63 | CDK8 | 0.53170705 |
| 64 | TTK | 0.52540614 |
| 65 | HCK | 0.50770041 |
| 66 | TLK1 | 0.49341489 |
| 67 | ZAP70 | 0.47555094 |
| 68 | EIF2AK3 | 0.47167434 |
| 69 | PRKD1 | 0.46362422 |
| 70 | PRKAA2 | 0.45293374 |
| 71 | ATR | 0.44951649 |
| 72 | PNCK | 0.44607473 |
| 73 | MATK | 0.43437329 |
| 74 | LYN | 0.42986472 |
| 75 | CSNK1A1L | 0.40681449 |
| 76 | CDK3 | 0.39971669 |
| 77 | PDPK1 | 0.36778283 |
| 78 | PKN1 | 0.36365276 |
| 79 | PAK1 | 0.36322788 |
| 80 | PRKCE | 0.35900459 |
| 81 | PDK2 | 0.35732308 |
| 82 | CSNK1D | 0.35266271 |
| 83 | TRPM7 | 0.34562521 |
| 84 | PLK1 | 0.33700311 |
| 85 | CAMKK2 | 0.32580288 |
| 86 | PIM1 | 0.31249194 |
| 87 | VRK1 | 0.31051434 |
| 88 | PRKACG | 0.30807513 |
| 89 | MAP2K6 | 0.30200048 |
| 90 | CCNB1 | 0.29778503 |
| 91 | PAK3 | 0.29759618 |
| 92 | IRAK1 | 0.29299144 |
| 93 | PRKG1 | 0.28239827 |
| 94 | ABL1 | 0.27791245 |
| 95 | FES | 0.27402095 |
| 96 | PRKACA | 0.26358684 |
| 97 | ATM | 0.25771531 |
| 98 | MAPKAPK5 | 0.25411834 |
| 99 | CAMK2A | 0.24204084 |
| 100 | IGF1R | 0.24090611 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phototransduction_Homo sapiens_hsa04744 | 3.59275198 |
| 2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.29519158 |
| 3 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 3.09970848 |
| 4 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.05476139 |
| 5 | Platelet activation_Homo sapiens_hsa04611 | 2.88299355 |
| 6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.71715204 |
| 7 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.42400223 |
| 8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.37157565 |
| 9 | Olfactory transduction_Homo sapiens_hsa04740 | 2.35021702 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.24724617 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.21876657 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.21435829 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 2.20371410 |
| 14 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.89357385 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.85962041 |
| 16 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.81153655 |
| 17 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.79753796 |
| 18 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.72029737 |
| 19 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.69843771 |
| 20 | Morphine addiction_Homo sapiens_hsa05032 | 1.65812845 |
| 21 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.64286739 |
| 22 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.63961413 |
| 23 | ABC transporters_Homo sapiens_hsa02010 | 1.61683235 |
| 24 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.60671222 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.58558474 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.57853034 |
| 27 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.57696961 |
| 28 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.53672287 |
| 29 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.45895388 |
| 30 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.43804968 |
| 31 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.42421566 |
| 32 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.36378856 |
| 33 | Taste transduction_Homo sapiens_hsa04742 | 1.32831841 |
| 34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.24273211 |
| 35 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.17512312 |
| 36 | GABAergic synapse_Homo sapiens_hsa04727 | 1.16778829 |
| 37 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.15882212 |
| 38 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.14737045 |
| 39 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.14273047 |
| 40 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.11395141 |
| 41 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.93318260 |
| 42 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.92922960 |
| 43 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.90018346 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.89520481 |
| 45 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.89264502 |
| 46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.88060644 |
| 47 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.87921949 |
| 48 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.86541297 |
| 49 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.85205618 |
| 50 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.84578379 |
| 51 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.84242883 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.83780297 |
| 53 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.82926415 |
| 54 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.82063943 |
| 55 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.80494027 |
| 56 | RNA polymerase_Homo sapiens_hsa03020 | 0.80107181 |
| 57 | Circadian entrainment_Homo sapiens_hsa04713 | 0.80065662 |
| 58 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.79378474 |
| 59 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.78632252 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.78604200 |
| 61 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.77280612 |
| 62 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.74764748 |
| 63 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.66722248 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.65912563 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65807716 |
| 66 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.62550149 |
| 67 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.61304446 |
| 68 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.60667977 |
| 69 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58694982 |
| 70 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.58527896 |
| 71 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.58157772 |
| 72 | Asthma_Homo sapiens_hsa05310 | 0.56163709 |
| 73 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.52535003 |
| 74 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.52452570 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51448640 |
| 76 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51413097 |
| 77 | Parkinsons disease_Homo sapiens_hsa05012 | 0.50186083 |
| 78 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.48115835 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47685043 |
| 80 | Peroxisome_Homo sapiens_hsa04146 | 0.46968112 |
| 81 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.44959013 |
| 82 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.44303087 |
| 83 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.42914962 |
| 84 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.39497602 |
| 85 | Gap junction_Homo sapiens_hsa04540 | 0.38245659 |
| 86 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.38115696 |
| 87 | Long-term depression_Homo sapiens_hsa04730 | 0.35684638 |
| 88 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.34986362 |
| 89 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.33510258 |
| 90 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.32939190 |
| 91 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.30006838 |
| 92 | Salivary secretion_Homo sapiens_hsa04970 | 0.29994680 |
| 93 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.28550487 |
| 94 | Cell cycle_Homo sapiens_hsa04110 | 0.27642146 |
| 95 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.27040541 |
| 96 | Alcoholism_Homo sapiens_hsa05034 | 0.25446736 |
| 97 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.23615232 |
| 98 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.23106343 |
| 99 | RNA degradation_Homo sapiens_hsa03018 | 0.23022666 |
| 100 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.22960362 |

