SMPX

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a small protein that has no known functional domains. Mutations in this gene are a cause of X-linked deafness-4, and the encoded protein may play a role in the maintenance of inner ear cells subjected to mechanical stress. Alternatively spliced transcript variants have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1muscle filament sliding (GO:0030049)9.18938790
2actin-myosin filament sliding (GO:0033275)9.18938790
3sarcomere organization (GO:0045214)8.73438546
4cardiac myofibril assembly (GO:0055003)8.61448405
5negative regulation of potassium ion transmembrane transporter activity (GO:1901017)8.20189306
6myofibril assembly (GO:0030239)8.02029361
7actin-mediated cell contraction (GO:0070252)7.62976157
8negative regulation of potassium ion transmembrane transport (GO:1901380)7.15612160
9regulation of skeletal muscle contraction (GO:0014819)7.03453717
10cardiac muscle contraction (GO:0060048)6.73636136
11tricarboxylic acid cycle (GO:0006099)6.53283208
12cardiac muscle cell development (GO:0055013)6.41769284
13regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.39502628
14positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.36595152
15regulation of relaxation of muscle (GO:1901077)6.09811304
16plasma membrane repair (GO:0001778)6.08536455
17cardiac cell development (GO:0055006)6.03562829
18sarcoplasmic reticulum calcium ion transport (GO:0070296)5.95906564
19actomyosin structure organization (GO:0031032)5.87282029
20regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.82814149
21cardiac muscle hypertrophy (GO:0003300)5.80232392
22cardiac muscle tissue morphogenesis (GO:0055008)5.76918129
23* striated muscle contraction (GO:0006941)5.76584288
24heart process (GO:0003015)5.75770588
25heart contraction (GO:0060047)5.75770588
26regulation of sarcomere organization (GO:0060297)5.73180749
27actin filament-based movement (GO:0030048)5.68529434
28striated muscle hypertrophy (GO:0014897)5.56289410
29regulation of actin filament-based movement (GO:1903115)5.54249632
30regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.53563859
31regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.41324362
32muscle tissue morphogenesis (GO:0060415)5.28149944
33ventricular cardiac muscle cell action potential (GO:0086005)5.25260358
34ventricular cardiac muscle tissue morphogenesis (GO:0055010)5.21049864
35mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.19802901
36heart trabecula formation (GO:0060347)5.14912370
37regulation of cell communication by electrical coupling (GO:0010649)5.14410212
38adult heart development (GO:0007512)5.13128092
39regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.10788429
40carnitine shuttle (GO:0006853)5.10271327
41regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.07456814
42energy coupled proton transport, down electrochemical gradient (GO:0015985)5.04796538
43ATP synthesis coupled proton transport (GO:0015986)5.04796538
44regulation of acyl-CoA biosynthetic process (GO:0050812)5.02797955
45muscle hypertrophy (GO:0014896)4.93489992
46skeletal muscle contraction (GO:0003009)4.90762180
47regulation of striated muscle contraction (GO:0006942)4.89209215
48bundle of His cell to Purkinje myocyte communication (GO:0086069)4.80860552
49oxidative phosphorylation (GO:0006119)4.65541955
50regulation of cofactor metabolic process (GO:0051193)4.64944541
51regulation of coenzyme metabolic process (GO:0051196)4.64944541
52response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.62626372
53regulation of membrane repolarization (GO:0060306)4.50286878
54skeletal muscle fiber development (GO:0048741)4.48457292
55respiratory electron transport chain (GO:0022904)4.43135626
56fatty acid transmembrane transport (GO:1902001)4.42009800
57cardiac muscle hypertrophy in response to stress (GO:0014898)4.37243236
58muscle hypertrophy in response to stress (GO:0003299)4.37243236
59cardiac muscle adaptation (GO:0014887)4.37243236
60regulation of the force of heart contraction (GO:0002026)4.36565300
61electron transport chain (GO:0022900)4.31335612
62mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.29769004
63myotube cell development (GO:0014904)4.29538579
64cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.17207804
65negative regulation of cardiac muscle cell apoptotic process (GO:0010667)4.11379188
66striated muscle cell development (GO:0055002)4.05559056
67muscle cell cellular homeostasis (GO:0046716)4.04819660
68negative regulation of protein localization to cell surface (GO:2000009)3.98719098
69cell communication involved in cardiac conduction (GO:0086065)3.98546655
70striated muscle adaptation (GO:0014888)3.97710921
71skeletal muscle tissue development (GO:0007519)3.95273029
72regulation of calcium ion transmembrane transporter activity (GO:1901019)3.94604117
73regulation of calcium ion transmembrane transport (GO:1903169)3.94604117
74* muscle contraction (GO:0006936)3.92350716
75regulation of cardioblast differentiation (GO:0051890)3.87109701
76cardiac muscle cell action potential involved in contraction (GO:0086002)3.81139390
77cytidine metabolic process (GO:0046087)3.80519113
78cytidine catabolic process (GO:0006216)3.80519113
79cytidine deamination (GO:0009972)3.80519113
80response to inactivity (GO:0014854)3.80406459
81cardiac muscle cell action potential (GO:0086001)3.77155246
82glycogen catabolic process (GO:0005980)3.76869246
83negative regulation of striated muscle cell apoptotic process (GO:0010664)3.76609746
84ventricular cardiac muscle cell development (GO:0055015)3.76280857
85membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.76134915
86carnitine transmembrane transport (GO:1902603)3.74853188
87regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.74768697
88relaxation of muscle (GO:0090075)3.74715062
89regulation of ATP catabolic process (GO:1903289)3.73989859
90regulation of ATPase activity (GO:0043462)3.73989859
91pyrimidine ribonucleoside catabolic process (GO:0046133)3.73575819
92regulation of sulfur metabolic process (GO:0042762)3.73336258
93negative regulation of potassium ion transport (GO:0043267)3.72894400
94regulation of heart rate (GO:0002027)3.67796491
95skeletal muscle adaptation (GO:0043501)3.67190051
96* muscle system process (GO:0003012)3.67129223
97glucan biosynthetic process (GO:0009250)3.64909334
98glycogen biosynthetic process (GO:0005978)3.64909334
99regulation of muscle system process (GO:0090257)3.64693580
100regulation of cardiac muscle contraction (GO:0055117)3.63464025
101negative regulation of calcium ion transmembrane transport (GO:1903170)3.62032741
102negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.62032741
103cell communication by electrical coupling (GO:0010644)3.57546335
104creatine metabolic process (GO:0006600)3.55842354
105muscle cell fate commitment (GO:0042693)3.54164343
106glucan catabolic process (GO:0009251)3.52995667
107NADH metabolic process (GO:0006734)3.49668029
108muscle adaptation (GO:0043500)3.49457657
109positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.49267508
110relaxation of cardiac muscle (GO:0055119)3.48121719
111muscle cell development (GO:0055001)3.46951110
1122-oxoglutarate metabolic process (GO:0006103)3.41713804
113regulation of heart contraction (GO:0008016)3.41690814
114carnitine transport (GO:0015879)3.40862179
115amino-acid betaine transport (GO:0015838)3.40862179
116regulation of muscle contraction (GO:0006937)3.39404685
117regulation of cardiac muscle cell contraction (GO:0086004)3.38621796
118cardiac chamber formation (GO:0003207)3.38271567
119muscle organ development (GO:0007517)3.37365441
120muscle fiber development (GO:0048747)3.37305463
121muscle structure development (GO:0061061)3.36698129
122positive regulation of cation channel activity (GO:2001259)3.35457992
123cardiac conduction (GO:0061337)3.35319474
124skeletal muscle tissue regeneration (GO:0043403)3.35209541
125response to muscle activity (GO:0014850)3.32915937
126positive regulation of myotube differentiation (GO:0010831)3.32492717
127cellular polysaccharide catabolic process (GO:0044247)3.32135828
128striated muscle atrophy (GO:0014891)3.30692883
129negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.30644234
130regulation of myoblast differentiation (GO:0045661)3.26789960

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.27899419
2EP300_21415370_ChIP-Seq_HL-1_Mouse5.50593099
3ESRRB_18555785_ChIP-Seq_MESCs_Mouse5.28779118
4TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.30460421
5TBX20_22080862_ChIP-Seq_HEART_Mouse4.27453673
6TBX20_22328084_ChIP-Seq_HEART_Mouse4.27453673
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.99076814
8RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.86232697
9MEF2A_21415370_ChIP-Seq_HL-1_Mouse3.84590639
10ESR1_20079471_ChIP-ChIP_T-47D_Human3.74719094
11CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.53661653
12GATA4_21415370_ChIP-Seq_HL-1_Mouse2.87004437
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.77370525
14ZNF263_19887448_ChIP-Seq_K562_Human2.70147692
15RARG_19884340_ChIP-ChIP_MEFs_Mouse2.57394310
16NKX2-5_21415370_ChIP-Seq_HL-1_Mouse2.20991242
17EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.19595189
18GATA1_22025678_ChIP-Seq_K562_Human2.15791118
19CDX2_19796622_ChIP-Seq_MESCs_Mouse2.12426707
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.09160798
21ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.99301712
22PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.89362693
23PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.85603594
24CLOCK_20551151_ChIP-Seq_293T_Human1.82891435
25NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.78058045
26ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.67895628
27BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.63150008
28TRIM28_21343339_ChIP-Seq_HEK293_Human1.58836623
29GBX2_23144817_ChIP-Seq_PC3_Human1.51283627
30NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.45835188
31TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.44067971
32NFIB_24661679_ChIP-Seq_LUNG_Mouse1.43534527
33THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.43046742
34ISL1_27105846_Chip-Seq_CPCs_Mouse1.39317476
35ZNF274_21170338_ChIP-Seq_K562_Hela1.38724182
36EZH2_27294783_Chip-Seq_ESCs_Mouse1.33510461
37PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.26159125
38CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.25979773
39BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.25451284
40EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.25267705
41HIF1A_21447827_ChIP-Seq_MCF-7_Human1.24372232
42PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.22198885
43EZH2_27304074_Chip-Seq_ESCs_Mouse1.21574136
44EZH2_22144423_ChIP-Seq_EOC_Human1.18661037
45ESR2_21235772_ChIP-Seq_MCF-7_Human1.15060310
46WT1_19549856_ChIP-ChIP_CCG9911_Human1.12499656
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.12159235
48RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.11778166
49SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11551640
50RNF2_18974828_ChIP-Seq_MESCs_Mouse1.09612471
51EZH2_18974828_ChIP-Seq_MESCs_Mouse1.09612471
52SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.08897844
53AUTS2_25519132_ChIP-Seq_293T-REX_Human1.08221001
54EZH2_27294783_Chip-Seq_NPCs_Mouse1.08136447
55ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.07093951
56SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.06487055
57MTF2_20144788_ChIP-Seq_MESCs_Mouse1.06486022
58CRX_20693478_ChIP-Seq_RETINA_Mouse1.06048181
59SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.05777685
60SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04872560
61CJUN_26792858_Chip-Seq_BT549_Human1.04750120
62CTCF_27219007_Chip-Seq_Bcells_Human1.03467431
63CBX2_27304074_Chip-Seq_ESCs_Mouse1.03217568
64PPARA_22158963_ChIP-Seq_LIVER_Mouse1.02709908
65DROSHA_22980978_ChIP-Seq_HELA_Human1.02337708
66PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.01564241
67SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.01048562
68LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.00694029
69PCGF2_27294783_Chip-Seq_ESCs_Mouse0.99634455
70TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97922208
71ATF3_27146783_Chip-Seq_COLON_Human0.95254952
72* FOXH1_21741376_ChIP-Seq_ESCs_Human0.94222073
73PCGF2_27294783_Chip-Seq_NPCs_Mouse0.93654586
74LXR_22158963_ChIP-Seq_LIVER_Mouse0.93481713
75SPI1_20517297_ChIP-Seq_HL60_Human0.93312840
76FLI1_27457419_Chip-Seq_LIVER_Mouse0.92856613
77KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.92713515
78RARB_27405468_Chip-Seq_BRAIN_Mouse0.91825517
79SMC3_22415368_ChIP-Seq_MEFs_Mouse0.91292996
80BCAT_22108803_ChIP-Seq_LS180_Human0.90202872
81IGF1R_20145208_ChIP-Seq_DFB_Human0.89962554
82NR3C1_23031785_ChIP-Seq_PC12_Mouse0.89781827
83TP63_22573176_ChIP-Seq_HFKS_Human0.89722780
84OCT4_20526341_ChIP-Seq_ESCs_Human0.89373245
85OCT4_21477851_ChIP-Seq_ESCs_Mouse0.89010800
86CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.88873441
87JARID2_20075857_ChIP-Seq_MESCs_Mouse0.88812165
88NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.88511287
89GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.88267219
90TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.87352349
91TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.86600264
92* SMAD4_21799915_ChIP-Seq_A2780_Human0.86528795
93HTT_18923047_ChIP-ChIP_STHdh_Human0.86398483
94ESR1_21235772_ChIP-Seq_MCF-7_Human0.86281931
95GATA1_19941826_ChIP-Seq_K562_Human0.85872470
96ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.82857855
97CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.82401880
98FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.81306585
99GF1_26923725_Chip-Seq_HPCs_Mouse0.81203530
100SRF_21415370_ChIP-Seq_HL-1_Mouse0.80926312
101WT1_25993318_ChIP-Seq_PODOCYTE_Human0.80801190
102KDM2B_26808549_Chip-Seq_DND41_Human0.80244591
103RACK7_27058665_Chip-Seq_MCF-7_Human0.80076624
104RUNX1_27514584_Chip-Seq_MCF-7_Human0.79840857
105MYC_27129775_Chip-Seq_CORNEA_Mouse0.79827289
106STAT3_1855785_ChIP-Seq_MESCs_Mouse0.79455438
107GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.78806966
108STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.78140913
109SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.77624046
110ZFP281_18757296_ChIP-ChIP_E14_Mouse0.77199421
111RBPJ_22232070_ChIP-Seq_NCS_Mouse0.77044696
112NR3C1_21868756_ChIP-Seq_MCF10A_Human0.76948947
113TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.76880976
114TBX5_21415370_ChIP-Seq_HL-1_Mouse0.76007352
115SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.75729480
116SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.75528751
117TDRD3_21172665_ChIP-Seq_MCF-7_Human0.75406602
118RXR_22158963_ChIP-Seq_LIVER_Mouse0.74923320
119EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.73954818
120NFE2_27457419_Chip-Seq_LIVER_Mouse0.73622689
121PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.73602339
122KDM2B_26808549_Chip-Seq_SUP-B15_Human0.73480824
123PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.73065709
124ZFP57_27257070_Chip-Seq_ESCs_Mouse0.72738190
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.72649224
126AR_21572438_ChIP-Seq_LNCaP_Human0.72191060
127LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.71981555
128JARID2_20064375_ChIP-Seq_MESCs_Mouse0.71632499
129SMAD3_21741376_ChIP-Seq_HESCs_Human0.71553890
130SOX9_24532713_ChIP-Seq_HFSC_Mouse0.71517185
131SOX2_21211035_ChIP-Seq_LN229_Gbm0.71504867
132P63_26484246_Chip-Seq_KERATINOCYTES_Human0.71299051
133CTCF_21964334_Chip-Seq_Bcells_Human0.69701520
134VDR_22108803_ChIP-Seq_LS180_Human0.69170028
135CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.67944105
136SALL4_18804426_ChIP-ChIP_XEN_Mouse0.67301708
137NANOG_20526341_ChIP-Seq_ESCs_Human0.67268502
138GATA2_19941826_ChIP-Seq_K562_Human0.66944652
139MYC_19829295_ChIP-Seq_ESCs_Human0.66603975
140ELK3_25401928_ChIP-Seq_HUVEC_Human0.66338358
141SMC1_22415368_ChIP-Seq_MEFs_Mouse0.65818927
142YY1_22570637_ChIP-Seq_MALME-3M_Human0.64959689
143CTCF_21964334_ChIP-Seq_BJAB-B_Human0.63871681
144GATA2_21666600_ChIP-Seq_HMVEC_Human0.63351873
145NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.62152453
146NRF2_20460467_ChIP-Seq_MEFs_Mouse0.62152453
147CTNNB1_20460455_ChIP-Seq_HCT116_Human0.61672653
148SMAD4_21741376_ChIP-Seq_HESCs_Human0.60543743
149EGR1_19032775_ChIP-ChIP_M12_Human0.59723414
150GATA3_24758297_ChIP-Seq_MCF-7_Human0.59402959
151UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.59323517

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004084_abnormal_cardiac_muscle5.76561705
2MP0002837_dystrophic_cardiac_calcinosis5.56138881
3MP0003646_muscle_fatigue5.36156973
4MP0000751_myopathy5.15939128
5MP0000749_muscle_degeneration4.86490243
6MP0004036_abnormal_muscle_relaxation4.67040759
7MP0004215_abnormal_myocardial_fiber4.29930879
8MP0005330_cardiomyopathy3.90895817
9MP0004145_abnormal_muscle_electrophysio3.64638727
10MP0004087_abnormal_muscle_fiber3.35136085
11MP0002972_abnormal_cardiac_muscle3.17099285
12MP0005620_abnormal_muscle_contractility3.03863606
13MP0002106_abnormal_muscle_physiology3.00131109
14MP0000750_abnormal_muscle_regeneration2.85742878
15MP0008775_abnormal_heart_ventricle2.83573085
16MP0003137_abnormal_impulse_conducting2.70314211
17MP0010630_abnormal_cardiac_muscle2.60301101
18MP0002269_muscular_atrophy2.58964095
19MP0004130_abnormal_muscle_cell2.57266742
20MP0001544_abnormal_cardiovascular_syste2.50262416
21MP0005385_cardiovascular_system_phenoty2.50262416
22MP0000747_muscle_weakness2.49785558
23MP0005369_muscle_phenotype2.43270374
24MP0004484_altered_response_of2.38810814
25MP0000759_abnormal_skeletal_muscle2.34021010
26MP0006138_congestive_heart_failure2.24555530
27MP0003828_pulmonary_edema2.21844232
28MP0003221_abnormal_cardiomyocyte_apopto2.11648081
29MP0004233_abnormal_muscle_weight2.11578967
30MP0006036_abnormal_mitochondrial_physio1.99614584
31MP0003950_abnormal_plasma_membrane1.95941375
32MP0004085_abnormal_heartbeat1.93285315
33MP0002127_abnormal_cardiovascular_syste1.78590048
34MP0004510_myositis1.76852591
35MP0002332_abnormal_exercise_endurance1.63227323
36MP0003567_abnormal_fetal_cardiomyocyte1.54466881
37MP0004270_analgesia1.16988763
38MP0006035_abnormal_mitochondrial_morpho1.16414431
39MP0000266_abnormal_heart_morphology1.14691034
40MP0005666_abnormal_adipose_tissue1.13285489
41MP0002234_abnormal_pharynx_morphology1.09809349
42MP0001661_extended_life_span1.05822059
43MP0000733_abnormal_muscle_development1.04876156
44MP0002108_abnormal_muscle_morphology1.03096983
45MP0000343_altered_response_to0.98085834
46MP0005266_abnormal_metabolism0.88225984
47MP0005165_increased_susceptibility_to0.85262393
48MP0004185_abnormal_adipocyte_glucose0.83778607
49MP0005451_abnormal_body_composition0.82806426
50MP0003279_aneurysm0.81071331
51MP0003806_abnormal_nucleotide_metabolis0.78165325
52MP0002822_catalepsy0.76008769
53MP0005375_adipose_tissue_phenotype0.73868316
54MP0000230_abnormal_systemic_arterial0.72653577
55MP0003045_fibrosis0.72555531
56MP0005670_abnormal_white_adipose0.71852800
57MP0002128_abnormal_blood_circulation0.71825894
58MP0003566_abnormal_cell_adhesion0.68346170
59MP0002971_abnormal_brown_adipose0.67739003
60MP0010368_abnormal_lymphatic_system0.67109316
61MP0004272_abnormal_basement_membrane0.64242780
62MP0004043_abnormal_pH_regulation0.60929897
63MP0003705_abnormal_hypodermis_morpholog0.60606526
64MP0005377_hearing/vestibular/ear_phenot0.60480468
65MP0003878_abnormal_ear_physiology0.60480468
66MP0000013_abnormal_adipose_tissue0.58220268
67MP0009384_cardiac_valve_regurgitation0.57460056
68MP0005275_abnormal_skin_tensile0.56885866
69MP0004147_increased_porphyrin_level0.54589136
70MP0008569_lethality_at_weaning0.52966073
71MP0005623_abnormal_meninges_morphology0.51854551
72MP0001299_abnormal_eye_distance/0.50480159
73MP0000767_abnormal_smooth_muscle0.48425766
74MP0002925_abnormal_cardiovascular_devel0.46470990
75MP0001879_abnormal_lymphatic_vessel0.45197045
76MP0003984_embryonic_growth_retardation0.43488212
77MP0002088_abnormal_embryonic_growth/wei0.43307668
78MP0000372_irregular_coat_pigmentation0.43142057
79MP0009780_abnormal_chondrocyte_physiolo0.42369235
80MP0002638_abnormal_pupillary_reflex0.42157567
81MP0001784_abnormal_fluid_regulation0.40928743
82MP0000003_abnormal_adipose_tissue0.40024257
83MP0005319_abnormal_enzyme/_coenzyme0.40002238
84MP0002078_abnormal_glucose_homeostasis0.37369764
85MP0008438_abnormal_cutaneous_collagen0.36633752
86MP0001614_abnormal_blood_vessel0.34245281
87MP0005167_abnormal_blood-brain_barrier0.33011208
88MP0001727_abnormal_embryo_implantation0.32595652
89MP0003948_abnormal_gas_homeostasis0.32289616
90MP0005187_abnormal_penis_morphology0.30481571
91MP0003879_abnormal_hair_cell0.29369503
92MP0003122_maternal_imprinting0.28863148
93MP0002909_abnormal_adrenal_gland0.28124240
94MP0008961_abnormal_basal_metabolism0.27806171
95MP0000762_abnormal_tongue_morphology0.26256674
96MP0004142_abnormal_muscle_tone0.26006580
97MP0003941_abnormal_skin_development0.25990018
98MP0004134_abnormal_chest_morphology0.25402688
99MP0009250_abnormal_appendicular_skeleto0.25288721
100MP0005584_abnormal_enzyme/coenzyme_acti0.23903909
101MP0005423_abnormal_somatic_nervous0.23650114
102MP0001984_abnormal_olfaction0.23548434
103MP0005380_embryogenesis_phenotype0.22573507
104MP0001672_abnormal_embryogenesis/_devel0.22573507
105MP0005332_abnormal_amino_acid0.22184517
106MP0005503_abnormal_tendon_morphology0.20876997
107MP0005535_abnormal_body_temperature0.20740094
108MP0008874_decreased_physiological_sensi0.20489963
109MP0002114_abnormal_axial_skeleton0.19934554
110MP0003123_paternal_imprinting0.19619715
111MP0004924_abnormal_behavior0.19402537
112MP0005386_behavior/neurological_phenoty0.19402537
113MP0010030_abnormal_orbit_morphology0.18735127
114MP0005595_abnormal_vascular_smooth0.18590611
115MP0005334_abnormal_fat_pad0.18085580
116MP0005452_abnormal_adipose_tissue0.18050239
117MP0003385_abnormal_body_wall0.17775344
118MP0005166_decreased_susceptibility_to0.17680923
119MP0009672_abnormal_birth_weight0.17042014
120MP0001485_abnormal_pinna_reflex0.16628739
121MP0002066_abnormal_motor_capabilities/c0.16622560
122MP0005376_homeostasis/metabolism_phenot0.16544834
123MP0002734_abnormal_mechanical_nocicepti0.16441207
124MP0005388_respiratory_system_phenotype0.16311297
125MP0002133_abnormal_respiratory_system0.16311297
126MP0003195_calcinosis0.15689476

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)7.11258505
2Exercise-induced muscle cramps (HP:0003710)6.98321931
3Exercise-induced myalgia (HP:0003738)6.88755709
4Calf muscle hypertrophy (HP:0008981)6.77977210
5Muscle hypertrophy of the lower extremities (HP:0008968)6.48587840
6Ventricular tachycardia (HP:0004756)5.82908919
7Subaortic stenosis (HP:0001682)5.34510325
8Abnormality of the left ventricular outflow tract (HP:0011103)5.34510325
9Muscle fiber splitting (HP:0003555)5.34409054
10Abnormality of the calf musculature (HP:0001430)5.30713565
11Hyporeflexia of lower limbs (HP:0002600)5.19779347
12Muscle fiber inclusion bodies (HP:0100299)5.14290355
13Atrial fibrillation (HP:0005110)5.11329525
14Myoglobinuria (HP:0002913)5.07113982
15Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.02770398
16Primary atrial arrhythmia (HP:0001692)4.76454974
17Lipoatrophy (HP:0100578)4.72304173
18Type 1 muscle fiber predominance (HP:0003803)4.64202934
19Supraventricular tachycardia (HP:0004755)4.60758880
20EMG: myopathic abnormalities (HP:0003458)4.57911615
21Nemaline bodies (HP:0003798)4.57212600
22Supraventricular arrhythmia (HP:0005115)4.50939145
23Right ventricular cardiomyopathy (HP:0011663)4.26266739
24Rhabdomyolysis (HP:0003201)4.09431312
25Syncope (HP:0001279)4.03606905
26Asymmetric septal hypertrophy (HP:0001670)4.02090214
27Dilated cardiomyopathy (HP:0001644)3.95839975
28Palpitations (HP:0001962)3.89970996
29Ventricular arrhythmia (HP:0004308)3.80248184
30Increased connective tissue (HP:0009025)3.75447973
31Prolonged QT interval (HP:0001657)3.75291686
32Difficulty running (HP:0009046)3.72500804
33Bundle branch block (HP:0011710)3.56436142
34Myotonia (HP:0002486)3.48231852
35Calcaneovalgus deformity (HP:0001848)3.40731348
36Distal arthrogryposis (HP:0005684)3.28563618
37Muscle stiffness (HP:0003552)3.23003827
38Neck muscle weakness (HP:0000467)3.16985537
39Ventricular fibrillation (HP:0001663)3.09704252
40Abnormal mitochondria in muscle tissue (HP:0008316)3.01119330
41Heart block (HP:0012722)3.00580890
42Deformed tarsal bones (HP:0008119)3.00514810
43Acute necrotizing encephalopathy (HP:0006965)3.00486579
44Distal lower limb muscle weakness (HP:0009053)2.84665300
45Abnormal atrioventricular conduction (HP:0005150)2.82639722
46Malignant hyperthermia (HP:0002047)2.81266962
47Round ear (HP:0100830)2.79672712
48Areflexia of lower limbs (HP:0002522)2.78618615
49Difficulty climbing stairs (HP:0003551)2.75632300
50Atrioventricular block (HP:0001678)2.74902292
51Myopathic facies (HP:0002058)2.73264142
52Abnormal EKG (HP:0003115)2.73237703
53Abnormality of skeletal muscle fiber size (HP:0012084)2.72594287
54Hepatic necrosis (HP:0002605)2.72412788
55Left ventricular hypertrophy (HP:0001712)2.69517422
56Rimmed vacuoles (HP:0003805)2.68635753
57Increased variability in muscle fiber diameter (HP:0003557)2.65603582
58Ragged-red muscle fibers (HP:0003200)2.63379789
59Conjunctival hamartoma (HP:0100780)2.62822192
60Abnormal finger flexion creases (HP:0006143)2.62242340
61Distal lower limb amyotrophy (HP:0008944)2.55249365
62Bulbar palsy (HP:0001283)2.54800942
63Fetal akinesia sequence (HP:0001989)2.54377916
64Weak cry (HP:0001612)2.53128146
65Acute encephalopathy (HP:0006846)2.51981525
66Progressive macrocephaly (HP:0004481)2.48479434
67Generalized muscle weakness (HP:0003324)2.42522848
68Palmoplantar keratoderma (HP:0000982)2.41164719
69Exercise intolerance (HP:0003546)2.39579252
70Abnormality of the neuromuscular junction (HP:0003398)2.38406268
71Fatigable weakness (HP:0003473)2.38406268
72Centrally nucleated skeletal muscle fibers (HP:0003687)2.37719351
73Mitochondrial inheritance (HP:0001427)2.37194233
74Hip contracture (HP:0003273)2.35641443
75EMG: neuropathic changes (HP:0003445)2.34505825
76Hepatocellular necrosis (HP:0001404)2.32221692
77Increased CSF lactate (HP:0002490)2.31635464
78Hypoglycemic coma (HP:0001325)2.31246299
79Ulnar deviation of the wrist (HP:0003049)2.29719913
80Abnormality of glycolysis (HP:0004366)2.25832903
81Increased serum pyruvate (HP:0003542)2.25832903
82Pheochromocytoma (HP:0002666)2.25020900
83Mildly elevated creatine phosphokinase (HP:0008180)2.22834682
84Cerebral edema (HP:0002181)2.21064022
85Ketoacidosis (HP:0001993)2.13198894
86Gowers sign (HP:0003391)2.12921729
87Popliteal pterygium (HP:0009756)2.12078384
88Abnormality of alanine metabolism (HP:0010916)2.09780402
89Hyperalaninemia (HP:0003348)2.09780402
90Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.09780402
91Hypoplastic ischia (HP:0003175)2.08877992
92Increased muscle lipid content (HP:0009058)2.07459458
93Limb-girdle muscle atrophy (HP:0003797)2.04367410
94Neuroendocrine neoplasm (HP:0100634)2.03861669
95Muscular dystrophy (HP:0003560)2.01390419
96Abnormality of the foot musculature (HP:0001436)2.01142117
97Abnormality of dicarboxylic acid metabolism (HP:0010995)2.00698596
98Dicarboxylic aciduria (HP:0003215)2.00698596
99Lactic acidosis (HP:0003128)2.00250347
100Neoplasm of the adrenal gland (HP:0100631)1.98494573
101Slender build (HP:0001533)1.98057233
102Proximal amyotrophy (HP:0007126)1.97867241
103Waddling gait (HP:0002515)1.97502934
104Type 2 muscle fiber atrophy (HP:0003554)1.96650843
105Lower limb amyotrophy (HP:0007210)1.94917285
106Progressive muscle weakness (HP:0003323)1.94445614
107Abnormality of the shoulder girdle musculature (HP:0001435)1.94112761
108Scapular winging (HP:0003691)1.93935732
109Respiratory insufficiency due to muscle weakness (HP:0002747)1.93186629
110Abnormality of fatty-acid metabolism (HP:0004359)1.92495260
111Facial diplegia (HP:0001349)1.92425228
112Increased intramyocellular lipid droplets (HP:0012240)1.90630900
113Frequent falls (HP:0002359)1.90080714
114Hamartoma of the eye (HP:0010568)1.89490557
115Double outlet right ventricle (HP:0001719)1.88979620
116Congenital malformation of the right heart (HP:0011723)1.88979620
117Spinal rigidity (HP:0003306)1.88706357
118Respiratory failure (HP:0002878)1.88233009
119Abnormality of the calcaneus (HP:0008364)1.88150540
120Foot dorsiflexor weakness (HP:0009027)1.84599187
121Hyperkalemia (HP:0002153)1.84232903
122Absent phalangeal crease (HP:0006109)1.82398403
123Muscle fiber atrophy (HP:0100295)1.78303945
124Steppage gait (HP:0003376)1.77795197
125Aplasia of the musculature (HP:0100854)1.64824919
126Limited hip movement (HP:0008800)1.64772401
127Limb-girdle muscle weakness (HP:0003325)1.60558873
128Hypoplastic heart (HP:0001961)1.56796780
129Abnormality of the musculature of the pelvis (HP:0001469)1.48902615

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN7.30631562
2TTN5.44249647
3PHKG23.81090623
4PHKG13.81090623
5PDK33.45607694
6PDK43.45607694
7MYLK3.43170233
8STK243.31142793
9PKN22.83707544
10DMPK2.77349398
11NEK12.71929738
12LMTK22.50587533
13PIK3CA2.31925932
14TRIB32.30182942
15PDK22.09546434
16MUSK2.03487702
17BCKDK2.01902508
18PINK11.76610365
19ZAK1.57477231
20TIE11.55746362
21ILK1.44473764
22MAP2K31.40183759
23PIK3CG1.30847717
24NME11.29234267
25MAP3K71.28874068
26STK38L1.25867139
27MARK11.22881085
28MAPK121.16101370
29TRPM71.11558226
30CDC42BPA1.09483745
31PAK30.97367454
32GRK70.94867573
33CAMK2D0.94035530
34WNK40.92111382
35LIMK10.91786135
36MAPKAPK30.91322803
37PRKD10.89151847
38ROCK10.88046360
39CCNB10.84399383
40EEF2K0.82120297
41MAP3K30.80237718
42FLT30.79687407
43PRKAA10.79621282
44PRKAA20.78521254
45MAP3K50.74111858
46DAPK30.72448790
47MOS0.71036505
48STK40.63269577
49INSRR0.62714366
50STK390.59503751
51NEK90.58747874
52MAPK40.56143575
53WNK10.54985952
54ERBB30.54097791
55RIPK10.53774258
56PKN10.53690693
57MAP2K40.53146435
58CAMK2B0.51826516
59CAMK40.51631149
60TAOK20.49296563
61AKT20.48896272
62PTK2B0.48701383
63NME20.47889350
64DYRK1B0.47521681
65CAMK10.46164543
66PRKACB0.45491307
67CAMK2A0.44870501
68MAP2K60.41486609
69CAMK2G0.41225790
70KSR20.40955460
71STK380.39597358
72ROCK20.39540735
73MAP3K100.39003486
74PRKD30.35717314
75MAP3K130.34134805
76PDGFRA0.34067301
77PRKACA0.33187835
78SGK30.31519553
79KDR0.30778991
80RPS6KC10.30729963
81RPS6KL10.30729963
82MAP3K60.29766810
83TGFBR20.29253873
84LATS10.28870604
85PTK60.27672995
86EPHA30.24958185
87SGK20.24945345
88SIK10.24612472
89PRKACG0.24367136
90MARK30.24285997
91PDPK10.23130997
92MAPK100.23001107
93PDK10.22887515
94RPS6KA60.22764549
95PRKG10.21918202
96MAP3K110.20769377
97MAPK110.20457580
98RPS6KB20.18866133
99ICK0.17896181
100RPS6KA10.17269495
101MARK20.16973129
102MAP3K10.16898061
103PRKCE0.16448121
104FGFR10.16050581
105PRPF4B0.15254018
106LATS20.15223930
107EPHB10.14962976
108ARAF0.14927656
109RPS6KB10.14002991
110EPHB20.13754471
111MAPK70.12679662
112SGK10.12516463
113ZAP700.12251316
114LRRK20.12196912
115RPS6KA30.11593403
116RAF10.10256524
117PRKCQ0.10028766
118MAP3K120.09933781
119DAPK20.09859886
120STK30.09619637
121STK110.09095367
122MAPKAPK20.09076958
123MAP2K10.08820123
124FER0.07385699
125PRKG20.07190360
126MTOR0.06793781

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000206.21288754
2Cardiac muscle contraction_Homo sapiens_hsa042604.76109651
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.10995119
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.83797541
5Dilated cardiomyopathy_Homo sapiens_hsa054143.72346261
6Parkinsons disease_Homo sapiens_hsa050123.66525719
7Oxidative phosphorylation_Homo sapiens_hsa001903.47003387
8Propanoate metabolism_Homo sapiens_hsa006403.06566929
9Alzheimers disease_Homo sapiens_hsa050102.65442867
10Carbon metabolism_Homo sapiens_hsa012002.58128858
11Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.57138961
12Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.55198014
13Fatty acid degradation_Homo sapiens_hsa000712.51209203
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.37158869
15Huntingtons disease_Homo sapiens_hsa050162.33715021
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.04407565
17Fatty acid metabolism_Homo sapiens_hsa012121.90172158
18Pyruvate metabolism_Homo sapiens_hsa006201.87645795
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.86105961
20Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.66743831
21Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.55990453
22Viral myocarditis_Homo sapiens_hsa054161.46441621
23Biosynthesis of amino acids_Homo sapiens_hsa012301.29722287
24Fatty acid elongation_Homo sapiens_hsa000621.22750486
25Glucagon signaling pathway_Homo sapiens_hsa049221.22273262
26Starch and sucrose metabolism_Homo sapiens_hsa005001.22162193
27cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11037105
28Insulin resistance_Homo sapiens_hsa049311.10008223
29Butanoate metabolism_Homo sapiens_hsa006501.03141508
30Insulin signaling pathway_Homo sapiens_hsa049101.01899439
31Adipocytokine signaling pathway_Homo sapiens_hsa049200.91304009
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.88698174
33HIF-1 signaling pathway_Homo sapiens_hsa040660.86160815
34Oxytocin signaling pathway_Homo sapiens_hsa049210.82790534
35Calcium signaling pathway_Homo sapiens_hsa040200.82317489
36Galactose metabolism_Homo sapiens_hsa000520.81018203
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79959288
38Tight junction_Homo sapiens_hsa045300.79789655
39PPAR signaling pathway_Homo sapiens_hsa033200.78866872
40Focal adhesion_Homo sapiens_hsa045100.76816477
41Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.75327867
42AMPK signaling pathway_Homo sapiens_hsa041520.72407868
43Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.71272758
44Nitrogen metabolism_Homo sapiens_hsa009100.68877160
45Long-term potentiation_Homo sapiens_hsa047200.68046998
46Central carbon metabolism in cancer_Homo sapiens_hsa052300.66327421
47Vascular smooth muscle contraction_Homo sapiens_hsa042700.65570499
48Fructose and mannose metabolism_Homo sapiens_hsa000510.63342807
49Salivary secretion_Homo sapiens_hsa049700.59981633
50beta-Alanine metabolism_Homo sapiens_hsa004100.57779787
51Circadian rhythm_Homo sapiens_hsa047100.53272986
52Arginine and proline metabolism_Homo sapiens_hsa003300.52015719
53Lysine degradation_Homo sapiens_hsa003100.48172089
54Phenylalanine metabolism_Homo sapiens_hsa003600.48010779
55Tryptophan metabolism_Homo sapiens_hsa003800.47105376
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40989812
57Arginine biosynthesis_Homo sapiens_hsa002200.39684135
58Longevity regulating pathway - mammal_Homo sapiens_hsa042110.39557563
59Peroxisome_Homo sapiens_hsa041460.37918846
60Adherens junction_Homo sapiens_hsa045200.36111034
61Long-term depression_Homo sapiens_hsa047300.35556224
62Type II diabetes mellitus_Homo sapiens_hsa049300.35507790
63ECM-receptor interaction_Homo sapiens_hsa045120.35418961
64Renin secretion_Homo sapiens_hsa049240.34671562
65Amphetamine addiction_Homo sapiens_hsa050310.34245933
66Fatty acid biosynthesis_Homo sapiens_hsa000610.33100075
67Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32135937
68Gastric acid secretion_Homo sapiens_hsa049710.31778060
69Metabolic pathways_Homo sapiens_hsa011000.29309456
70Leukocyte transendothelial migration_Homo sapiens_hsa046700.27065206
71cAMP signaling pathway_Homo sapiens_hsa040240.26305979
72GABAergic synapse_Homo sapiens_hsa047270.26236482
73Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.25851017
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.25779919
75Amoebiasis_Homo sapiens_hsa051460.24458562
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.24187314
77Proteoglycans in cancer_Homo sapiens_hsa052050.22363972
78Insulin secretion_Homo sapiens_hsa049110.22176446
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.21890424
80Regulation of actin cytoskeleton_Homo sapiens_hsa048100.20080853
81Regulation of autophagy_Homo sapiens_hsa041400.19552202
82Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.19401759
83Pentose phosphate pathway_Homo sapiens_hsa000300.17865501
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.17728578
85Tyrosine metabolism_Homo sapiens_hsa003500.17575041
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.17507827
87mTOR signaling pathway_Homo sapiens_hsa041500.17435678
88FoxO signaling pathway_Homo sapiens_hsa040680.16969748
89Olfactory transduction_Homo sapiens_hsa047400.16861148
90Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.14974291
91GnRH signaling pathway_Homo sapiens_hsa049120.14821801
92Dopaminergic synapse_Homo sapiens_hsa047280.12133868
93Circadian entrainment_Homo sapiens_hsa047130.11167882
94Platelet activation_Homo sapiens_hsa046110.11048789
95Aldosterone synthesis and secretion_Homo sapiens_hsa049250.10413426
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.09534855
97Glycerophospholipid metabolism_Homo sapiens_hsa005640.08897716
98Renal cell carcinoma_Homo sapiens_hsa052110.08793035
99Fat digestion and absorption_Homo sapiens_hsa049750.08714037
100Sulfur metabolism_Homo sapiens_hsa009200.06483786
101VEGF signaling pathway_Homo sapiens_hsa043700.05923210
102Ovarian steroidogenesis_Homo sapiens_hsa049130.02787236
103MAPK signaling pathway_Homo sapiens_hsa040100.00805417
104PI3K-Akt signaling pathway_Homo sapiens_hsa04151-0.0641231
105Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964-0.0526102
106Melanogenesis_Homo sapiens_hsa04916-0.0514510
107Bile secretion_Homo sapiens_hsa04976-0.0499683
108AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933-0.0368421
109Cholinergic synapse_Homo sapiens_hsa04725-0.0313296
110Glycerolipid metabolism_Homo sapiens_hsa00561-0.0297424
111Toxoplasmosis_Homo sapiens_hsa05145-0.0264544
112Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961-0.0125090
113Small cell lung cancer_Homo sapiens_hsa05222-0.0122554
114Pancreatic secretion_Homo sapiens_hsa04972-0.0115138
115Gap junction_Homo sapiens_hsa04540-0.0066045

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