

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | retinal cone cell development (GO:0046549) | 4.97278711 |
| 2 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 4.53620941 |
| 3 | rhodopsin mediated signaling pathway (GO:0016056) | 4.27460324 |
| 4 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.15500137 |
| 5 | behavioral response to nicotine (GO:0035095) | 4.01673382 |
| 6 | viral mRNA export from host cell nucleus (GO:0046784) | 3.78968753 |
| 7 | kinetochore organization (GO:0051383) | 3.62510166 |
| 8 | presynaptic membrane assembly (GO:0097105) | 3.42760189 |
| 9 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.40629534 |
| 10 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.37552290 |
| 11 | nucleobase catabolic process (GO:0046113) | 3.33803767 |
| 12 | mitotic metaphase plate congression (GO:0007080) | 3.32019443 |
| 13 | nonmotile primary cilium assembly (GO:0035058) | 3.31857471 |
| 14 | kinetochore assembly (GO:0051382) | 3.29803984 |
| 15 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.28532279 |
| 16 | detection of light stimulus involved in visual perception (GO:0050908) | 3.28532279 |
| 17 | eye photoreceptor cell development (GO:0042462) | 3.28270880 |
| 18 | CENP-A containing nucleosome assembly (GO:0034080) | 3.24138286 |
| 19 | axonal fasciculation (GO:0007413) | 3.23515511 |
| 20 | auditory behavior (GO:0031223) | 3.23513058 |
| 21 | histone H2A acetylation (GO:0043968) | 3.22563076 |
| 22 | photoreceptor cell development (GO:0042461) | 3.20558216 |
| 23 | pyrimidine dimer repair (GO:0006290) | 3.19621893 |
| 24 | chromatin remodeling at centromere (GO:0031055) | 3.17395562 |
| 25 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.13146683 |
| 26 | head development (GO:0060322) | 3.12745330 |
| 27 | metaphase plate congression (GO:0051310) | 3.06312945 |
| 28 | hindbrain development (GO:0030902) | 3.02661083 |
| 29 | regulation of DNA damage checkpoint (GO:2000001) | 2.96714788 |
| 30 | protein prenylation (GO:0018342) | 2.95994916 |
| 31 | prenylation (GO:0097354) | 2.95994916 |
| 32 | presynaptic membrane organization (GO:0097090) | 2.95599547 |
| 33 | photoreceptor cell maintenance (GO:0045494) | 2.94469067 |
| 34 | neuron recognition (GO:0008038) | 2.93597385 |
| 35 | neural tube formation (GO:0001841) | 2.93228944 |
| 36 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.92815554 |
| 37 | protein heterotetramerization (GO:0051290) | 2.92515039 |
| 38 | limb bud formation (GO:0060174) | 2.91753118 |
| 39 | regulation of DNA endoreduplication (GO:0032875) | 2.90811367 |
| 40 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.90620420 |
| 41 | retinal ganglion cell axon guidance (GO:0031290) | 2.89909542 |
| 42 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.89800285 |
| 43 | somite rostral/caudal axis specification (GO:0032525) | 2.89035652 |
| 44 | spinal cord development (GO:0021510) | 2.86848126 |
| 45 | neuronal action potential propagation (GO:0019227) | 2.83466849 |
| 46 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.81044336 |
| 47 | olfactory bulb development (GO:0021772) | 2.80278604 |
| 48 | transmission of nerve impulse (GO:0019226) | 2.79675011 |
| 49 | behavioral response to ethanol (GO:0048149) | 2.79642819 |
| 50 | somite development (GO:0061053) | 2.78543363 |
| 51 | microtubule depolymerization (GO:0007019) | 2.78387615 |
| 52 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.76702427 |
| 53 | mechanosensory behavior (GO:0007638) | 2.76113981 |
| 54 | atrial cardiac muscle cell action potential (GO:0086014) | 2.72787586 |
| 55 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.72513924 |
| 56 | DNA replication-independent nucleosome organization (GO:0034724) | 2.72513924 |
| 57 | purine nucleobase biosynthetic process (GO:0009113) | 2.72257831 |
| 58 | mRNA splice site selection (GO:0006376) | 2.71144172 |
| 59 | tRNA methylation (GO:0030488) | 2.68976555 |
| 60 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.67804440 |
| 61 | sympathetic nervous system development (GO:0048485) | 2.66273021 |
| 62 | positive regulation of guanylate cyclase activity (GO:0031284) | 2.64441648 |
| 63 | spindle checkpoint (GO:0031577) | 2.63006658 |
| 64 | photoreceptor cell differentiation (GO:0046530) | 2.62273697 |
| 65 | eye photoreceptor cell differentiation (GO:0001754) | 2.62273697 |
| 66 | histone exchange (GO:0043486) | 2.61420804 |
| 67 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.61098689 |
| 68 | GMP metabolic process (GO:0046037) | 2.58396396 |
| 69 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.56361004 |
| 70 | regulation of telomere maintenance (GO:0032204) | 2.55151140 |
| 71 | histone H3-K4 methylation (GO:0051568) | 2.54536109 |
| 72 | synapse assembly (GO:0007416) | 2.54413918 |
| 73 | regulation of spindle organization (GO:0090224) | 2.53888156 |
| 74 | regulation of mRNA splicing, via spliceosome (GO:0048024) | 2.53583721 |
| 75 | spindle assembly checkpoint (GO:0071173) | 2.52935271 |
| 76 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.52794372 |
| 77 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.52308564 |
| 78 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.52308564 |
| 79 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.52308564 |
| 80 | negative regulation of sister chromatid segregation (GO:0033046) | 2.52308564 |
| 81 | protein localization to cilium (GO:0061512) | 2.50338977 |
| 82 | forebrain neuron differentiation (GO:0021879) | 2.49367262 |
| 83 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 2.49015359 |
| 84 | dendrite morphogenesis (GO:0048813) | 2.48362118 |
| 85 | establishment of chromosome localization (GO:0051303) | 2.47881069 |
| 86 | mitotic sister chromatid cohesion (GO:0007064) | 2.47703560 |
| 87 | dendritic spine morphogenesis (GO:0060997) | 2.47147744 |
| 88 | negative regulation of axon guidance (GO:1902668) | 2.46198518 |
| 89 | mitotic spindle assembly checkpoint (GO:0007094) | 2.45871269 |
| 90 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.44961602 |
| 91 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.44481833 |
| 92 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.43845350 |
| 93 | mannosylation (GO:0097502) | 2.42680324 |
| 94 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.42239748 |
| 95 | negative regulation of chromosome segregation (GO:0051985) | 2.42156214 |
| 96 | mitotic spindle checkpoint (GO:0071174) | 2.40988462 |
| 97 | adult walking behavior (GO:0007628) | 2.39754860 |
| 98 | negative regulation of astrocyte differentiation (GO:0048712) | 2.39535396 |
| 99 | postsynaptic membrane organization (GO:0001941) | 2.38868138 |
| 100 | establishment of mitochondrion localization (GO:0051654) | 2.38277168 |
| 101 | single strand break repair (GO:0000012) | 2.37978077 |
| 102 | cerebral cortex cell migration (GO:0021795) | 2.37547969 |
| 103 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.37322292 |
| 104 | limb development (GO:0060173) | 2.37126779 |
| 105 | appendage development (GO:0048736) | 2.37126779 |
| 106 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.37068661 |
| 107 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.36745945 |
| 108 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.36745945 |
| 109 | regulation of sister chromatid segregation (GO:0033045) | 2.36745945 |
| 110 | gamma-aminobutyric acid transport (GO:0015812) | 2.35987575 |
| 111 | RNA capping (GO:0036260) | 2.35628804 |
| 112 | 7-methylguanosine RNA capping (GO:0009452) | 2.35628804 |
| 113 | protein localization to synapse (GO:0035418) | 2.35467247 |
| 114 | 7-methylguanosine mRNA capping (GO:0006370) | 2.35148013 |
| 115 | cilium organization (GO:0044782) | 2.34980180 |
| 116 | cilium assembly (GO:0042384) | 2.34879085 |
| 117 | negative regulation of DNA recombination (GO:0045910) | 2.33981330 |
| 118 | DNA topological change (GO:0006265) | 2.33571708 |
| 119 | mitotic recombination (GO:0006312) | 2.33469029 |
| 120 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.33027058 |
| 121 | central nervous system neuron axonogenesis (GO:0021955) | 2.32797096 |
| 122 | histone H3-K4 trimethylation (GO:0080182) | 2.32240477 |
| 123 | intraciliary transport (GO:0042073) | 2.32203647 |
| 124 | meiotic chromosome segregation (GO:0045132) | 2.31949812 |
| 125 | protein localization to microtubule cytoskeleton (GO:0072698) | 2.31841846 |
| 126 | positive regulation of DNA-templated transcription, elongation (GO:0032786) | 2.31224079 |
| 127 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.31123132 |
| 128 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.30573801 |
| 129 | cilium morphogenesis (GO:0060271) | 2.30521650 |
| 130 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.30127419 |
| 131 | regulation of guanylate cyclase activity (GO:0031282) | 2.29976777 |
| 132 | DNA demethylation (GO:0080111) | 2.29369476 |
| 133 | rRNA modification (GO:0000154) | 2.28811025 |
| 134 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.28796086 |
| 135 | startle response (GO:0001964) | 2.28421492 |
| 136 | ATP-dependent chromatin remodeling (GO:0043044) | 2.28133833 |
| 137 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.27500815 |
| 138 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.27500815 |
| 139 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.27397110 |
| 140 | regulation of growth hormone secretion (GO:0060123) | 2.27038196 |
| 141 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.26591419 |
| 142 | intra-S DNA damage checkpoint (GO:0031573) | 2.26499324 |
| 143 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.25998026 |
| 144 | neuromuscular synaptic transmission (GO:0007274) | 2.25806092 |
| 145 | telomere maintenance via recombination (GO:0000722) | 2.25642359 |
| 146 | rRNA methylation (GO:0031167) | 2.25132108 |
| 147 | regulation of RNA export from nucleus (GO:0046831) | 2.24770813 |
| 148 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.24613837 |
| 149 | hippocampus development (GO:0021766) | 2.23128353 |
| 150 | neuron cell-cell adhesion (GO:0007158) | 2.22468981 |
| 151 | regulation of neurotransmitter uptake (GO:0051580) | 2.20432818 |
| 152 | neuron migration (GO:0001764) | 2.20374676 |
| 153 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.20238572 |
| 154 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.20167483 |
| 155 | behavioral response to cocaine (GO:0048148) | 2.19858176 |
| 156 | negative regulation of appetite (GO:0032099) | 2.19599092 |
| 157 | negative regulation of response to food (GO:0032096) | 2.19599092 |
| 158 | behavioral fear response (GO:0001662) | 2.19415427 |
| 159 | behavioral defense response (GO:0002209) | 2.19415427 |
| 160 | negative regulation of neurotransmitter transport (GO:0051589) | 2.19347907 |
| 161 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.18579824 |
| 162 | negative chemotaxis (GO:0050919) | 2.17772771 |
| 163 | otic vesicle formation (GO:0030916) | 2.17492595 |
| 164 | resolution of meiotic recombination intermediates (GO:0000712) | 2.17168143 |
| 165 | epithelial cilium movement (GO:0003351) | 2.15431996 |
| 166 | glutamate receptor signaling pathway (GO:0007215) | 2.14847771 |
| 167 | reflex (GO:0060004) | 2.14044187 |
| 168 | synapsis (GO:0007129) | 2.13522067 |
| 169 | peristalsis (GO:0030432) | 2.12967132 |
| 170 | cell proliferation in forebrain (GO:0021846) | 2.12338053 |
| 171 | vocalization behavior (GO:0071625) | 2.11625465 |
| 172 | dendrite development (GO:0016358) | 2.11496059 |
| 173 | seminiferous tubule development (GO:0072520) | 2.11447008 |
| 174 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.11416027 |
| 175 | synapse organization (GO:0050808) | 2.10986795 |
| 176 | microtubule anchoring (GO:0034453) | 2.10641742 |
| 177 | retina layer formation (GO:0010842) | 2.10597754 |
| 178 | centriole replication (GO:0007099) | 2.10418289 |
| 179 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.09819877 |
| 180 | synaptic transmission, glutamatergic (GO:0035249) | 2.09721218 |
| 181 | neuron-neuron synaptic transmission (GO:0007270) | 2.09514073 |
| 182 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.08178480 |
| 183 | spinal cord motor neuron differentiation (GO:0021522) | 2.07091078 |
| 184 | regulation of meiosis I (GO:0060631) | 2.06949053 |
| 185 | positive regulation of mitochondrial fission (GO:0090141) | 2.06723194 |
| 186 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.06573392 |
| 187 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.06573392 |
| 188 | positive regulation of synapse assembly (GO:0051965) | 2.06258526 |
| 189 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.06073859 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.91483245 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.83021924 |
| 3 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.87118731 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.84253812 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.84174798 |
| 6 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.65185316 |
| 7 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.51164445 |
| 8 | FUS_26573619_Chip-Seq_HEK293_Human | 2.50326862 |
| 9 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.49179800 |
| 10 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.42198054 |
| 11 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.36527810 |
| 12 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.32250693 |
| 13 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.31116604 |
| 14 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.23371661 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.21085613 |
| 16 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.18420858 |
| 17 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.14612288 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.13862865 |
| 19 | VDR_22108803_ChIP-Seq_LS180_Human | 2.13320865 |
| 20 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.10586879 |
| 21 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.04295730 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 2.03415066 |
| 23 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.99887768 |
| 24 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.97392641 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.97255691 |
| 26 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.88265842 |
| 27 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.80826472 |
| 28 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.80184418 |
| 29 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.79361961 |
| 30 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.74972170 |
| 31 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.74296980 |
| 32 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.73016937 |
| 33 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.72506742 |
| 34 | STAT3_23295773_ChIP-Seq_U87_Human | 1.65029461 |
| 35 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.64432961 |
| 36 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.60176474 |
| 37 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.60001648 |
| 38 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.58206411 |
| 39 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.57754505 |
| 40 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.56385137 |
| 41 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.56279479 |
| 42 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.54738177 |
| 43 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54400794 |
| 44 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.53574225 |
| 45 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.52587047 |
| 46 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.50295050 |
| 47 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.49218287 |
| 48 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.46964585 |
| 49 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.45154858 |
| 50 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.44467925 |
| 51 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.44367021 |
| 52 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.44201695 |
| 53 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.43849396 |
| 54 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.43416748 |
| 55 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.41999707 |
| 56 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.40966312 |
| 57 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.39580692 |
| 58 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.39569564 |
| 59 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.39052512 |
| 60 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.38696817 |
| 61 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.37753559 |
| 62 | AR_25329375_ChIP-Seq_VCAP_Human | 1.36605627 |
| 63 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.36302757 |
| 64 | P300_19829295_ChIP-Seq_ESCs_Human | 1.35291600 |
| 65 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.35071326 |
| 66 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.34834795 |
| 67 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.34251105 |
| 68 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.33939759 |
| 69 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.33183372 |
| 70 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32390083 |
| 71 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.32390083 |
| 72 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.31942992 |
| 73 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.31430549 |
| 74 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.30892955 |
| 75 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.30514244 |
| 76 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.29844000 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.28458816 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.28458816 |
| 79 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.28416298 |
| 80 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.27960417 |
| 81 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.26704864 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.26251715 |
| 83 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.23230443 |
| 84 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.22817823 |
| 85 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.22533008 |
| 86 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.22236794 |
| 87 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.21481154 |
| 88 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21347550 |
| 89 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 1.20721610 |
| 90 | TP53_16413492_ChIP-PET_HCT116_Human | 1.20660059 |
| 91 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.19891072 |
| 92 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17236578 |
| 93 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.17024505 |
| 94 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.16883034 |
| 95 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.16791708 |
| 96 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16582828 |
| 97 | * SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.16480126 |
| 98 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.15829123 |
| 99 | JUN_21703547_ChIP-Seq_K562_Human | 1.15424076 |
| 100 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.14365127 |
| 101 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.13546757 |
| 102 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.12469443 |
| 103 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.12109143 |
| 104 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.11892261 |
| 105 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.11371838 |
| 106 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.11031710 |
| 107 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.09956504 |
| 108 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.08993698 |
| 109 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.08692255 |
| 110 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.08651265 |
| 111 | * TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.08040642 |
| 112 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.07403000 |
| 113 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.06538729 |
| 114 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.06530002 |
| 115 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.06502214 |
| 116 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.06369745 |
| 117 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.05976826 |
| 118 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.05923062 |
| 119 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.05923062 |
| 120 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05289910 |
| 121 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.05042710 |
| 122 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.04881037 |
| 123 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.04851468 |
| 124 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04456572 |
| 125 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.03695494 |
| 126 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.03133076 |
| 127 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.02969166 |
| 128 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.02819466 |
| 129 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.02073155 |
| 130 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.01995922 |
| 131 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01658310 |
| 132 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01284275 |
| 133 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.01255427 |
| 134 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.99788602 |
| 135 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.99722240 |
| 136 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.98759832 |
| 137 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.98699946 |
| 138 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.97863329 |
| 139 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.97388120 |
| 140 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.96016473 |
| 141 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.95838319 |
| 142 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.95117091 |
| 143 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.94726680 |
| 144 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94291946 |
| 145 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.94228408 |
| 146 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.93828653 |
| 147 | TCF4_23295773_ChIP-Seq_U87_Human | 0.93278216 |
| 148 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.93122748 |
| 149 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.92626636 |
| 150 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.92432458 |
| 151 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.91987608 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 2.97720401 |
| 2 | MP0005551_abnormal_eye_electrophysiolog | 2.94967321 |
| 3 | MP0001986_abnormal_taste_sensitivity | 2.86928189 |
| 4 | MP0008057_abnormal_DNA_replication | 2.65133598 |
| 5 | MP0003787_abnormal_imprinting | 2.59588306 |
| 6 | MP0008058_abnormal_DNA_repair | 2.52112991 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.47622343 |
| 8 | MP0003880_abnormal_central_pattern | 2.37738185 |
| 9 | MP0001188_hyperpigmentation | 2.35893130 |
| 10 | MP0005646_abnormal_pituitary_gland | 2.32392295 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 2.20224620 |
| 12 | MP0005253_abnormal_eye_physiology | 2.17574346 |
| 13 | MP0010094_abnormal_chromosome_stability | 2.14136006 |
| 14 | MP0002638_abnormal_pupillary_reflex | 2.09733555 |
| 15 | MP0000566_synostosis | 2.07895741 |
| 16 | MP0003121_genomic_imprinting | 2.06433141 |
| 17 | MP0002822_catalepsy | 2.06416853 |
| 18 | MP0008789_abnormal_olfactory_epithelium | 2.04823545 |
| 19 | MP0005499_abnormal_olfactory_system | 2.02843049 |
| 20 | MP0005394_taste/olfaction_phenotype | 2.02843049 |
| 21 | MP0005423_abnormal_somatic_nervous | 1.93100587 |
| 22 | MP0004859_abnormal_synaptic_plasticity | 1.92213941 |
| 23 | MP0001984_abnormal_olfaction | 1.90213834 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.85001401 |
| 25 | MP0008877_abnormal_DNA_methylation | 1.83079931 |
| 26 | MP0003111_abnormal_nucleus_morphology | 1.81913138 |
| 27 | MP0005187_abnormal_penis_morphology | 1.68147365 |
| 28 | MP0002735_abnormal_chemical_nociception | 1.67216484 |
| 29 | MP0006276_abnormal_autonomic_nervous | 1.65224662 |
| 30 | MP0009046_muscle_twitch | 1.63519050 |
| 31 | MP0002938_white_spotting | 1.62656113 |
| 32 | MP0003077_abnormal_cell_cycle | 1.61912754 |
| 33 | MP0004133_heterotaxia | 1.58417712 |
| 34 | MP0000015_abnormal_ear_pigmentation | 1.51699682 |
| 35 | MP0000049_abnormal_middle_ear | 1.47723640 |
| 36 | MP0002160_abnormal_reproductive_system | 1.44889689 |
| 37 | MP0000569_abnormal_digit_pigmentation | 1.44151337 |
| 38 | MP0004957_abnormal_blastocyst_morpholog | 1.42121594 |
| 39 | MP0001968_abnormal_touch/_nociception | 1.41453306 |
| 40 | MP0000631_abnormal_neuroendocrine_gland | 1.40443472 |
| 41 | MP0004885_abnormal_endolymph | 1.36546827 |
| 42 | MP0003123_paternal_imprinting | 1.34830702 |
| 43 | MP0005409_darkened_coat_color | 1.31748471 |
| 44 | MP0009697_abnormal_copulation | 1.30137075 |
| 45 | MP0008932_abnormal_embryonic_tissue | 1.26169354 |
| 46 | MP0005386_behavior/neurological_phenoty | 1.25236645 |
| 47 | MP0004924_abnormal_behavior | 1.25236645 |
| 48 | MP0005171_absent_coat_pigmentation | 1.24880509 |
| 49 | MP0005391_vision/eye_phenotype | 1.24413826 |
| 50 | MP0004215_abnormal_myocardial_fiber | 1.24393354 |
| 51 | MP0000955_abnormal_spinal_cord | 1.23353213 |
| 52 | MP0002163_abnormal_gland_morphology | 1.23042780 |
| 53 | MP0000778_abnormal_nervous_system | 1.21221218 |
| 54 | MP0002064_seizures | 1.21201486 |
| 55 | MP0004142_abnormal_muscle_tone | 1.20868423 |
| 56 | MP0001486_abnormal_startle_reflex | 1.18747900 |
| 57 | MP0005195_abnormal_posterior_eye | 1.15919341 |
| 58 | MP0002234_abnormal_pharynx_morphology | 1.15147815 |
| 59 | MP0005645_abnormal_hypothalamus_physiol | 1.14194845 |
| 60 | MP0003937_abnormal_limbs/digits/tail_de | 1.14136376 |
| 61 | MP0003938_abnormal_ear_development | 1.13255352 |
| 62 | MP0003136_yellow_coat_color | 1.12205643 |
| 63 | MP0003122_maternal_imprinting | 1.11624678 |
| 64 | MP0000427_abnormal_hair_cycle | 1.11463792 |
| 65 | MP0002837_dystrophic_cardiac_calcinosis | 1.10832080 |
| 66 | MP0008007_abnormal_cellular_replicative | 1.09726863 |
| 67 | MP0002736_abnormal_nociception_after | 1.09371724 |
| 68 | MP0002102_abnormal_ear_morphology | 1.08928421 |
| 69 | MP0002177_abnormal_outer_ear | 1.06987054 |
| 70 | MP0002127_abnormal_cardiovascular_syste | 1.06729464 |
| 71 | MP0002184_abnormal_innervation | 1.06264697 |
| 72 | MP0004811_abnormal_neuron_physiology | 1.05622569 |
| 73 | MP0002095_abnormal_skin_pigmentation | 1.05266170 |
| 74 | MP0002734_abnormal_mechanical_nocicepti | 1.03136728 |
| 75 | MP0001485_abnormal_pinna_reflex | 1.03046059 |
| 76 | MP0001324_abnormal_eye_pigmentation | 1.03034371 |
| 77 | MP0003567_abnormal_fetal_cardiomyocyte | 1.02953278 |
| 78 | MP0002653_abnormal_ependyma_morphology | 1.02777984 |
| 79 | MP0003763_abnormal_thymus_physiology | 1.02116766 |
| 80 | MP0002752_abnormal_somatic_nervous | 1.01704202 |
| 81 | MP0003941_abnormal_skin_development | 1.01196885 |
| 82 | MP0003011_delayed_dark_adaptation | 1.00962476 |
| 83 | MP0005379_endocrine/exocrine_gland_phen | 1.00828869 |
| 84 | MP0001529_abnormal_vocalization | 1.00541432 |
| 85 | MP0003183_abnormal_peptide_metabolism | 1.00053119 |
| 86 | MP0000372_irregular_coat_pigmentation | 0.99727042 |
| 87 | MP0001293_anophthalmia | 0.97658653 |
| 88 | MP0009780_abnormal_chondrocyte_physiolo | 0.97185504 |
| 89 | MP0010030_abnormal_orbit_morphology | 0.96307389 |
| 90 | MP0002557_abnormal_social/conspecific_i | 0.95917399 |
| 91 | MP0000678_abnormal_parathyroid_gland | 0.94026851 |
| 92 | MP0000534_abnormal_ureter_morphology | 0.93747787 |
| 93 | MP0003861_abnormal_nervous_system | 0.93660093 |
| 94 | MP0004147_increased_porphyrin_level | 0.93394229 |
| 95 | MP0001299_abnormal_eye_distance/ | 0.93139031 |
| 96 | MP0003890_abnormal_embryonic-extraembry | 0.91757920 |
| 97 | MP0003385_abnormal_body_wall | 0.90615695 |
| 98 | MP0002751_abnormal_autonomic_nervous | 0.90609606 |
| 99 | MP0008995_early_reproductive_senescence | 0.90409211 |
| 100 | MP0005389_reproductive_system_phenotype | 0.89579988 |
| 101 | MP0003718_maternal_effect | 0.89481044 |
| 102 | MP0003942_abnormal_urinary_system | 0.88965710 |
| 103 | MP0002009_preneoplasia | 0.88502665 |
| 104 | MP0001286_abnormal_eye_development | 0.87311335 |
| 105 | MP0002067_abnormal_sensory_capabilities | 0.87242931 |
| 106 | MP0001346_abnormal_lacrimal_gland | 0.87113415 |
| 107 | MP0005248_abnormal_Harderian_gland | 0.86877938 |
| 108 | MP0003635_abnormal_synaptic_transmissio | 0.86655310 |
| 109 | MP0002882_abnormal_neuron_morphology | 0.86519722 |
| 110 | MP0000026_abnormal_inner_ear | 0.86093273 |
| 111 | MP0002909_abnormal_adrenal_gland | 0.86075715 |
| 112 | MP0002210_abnormal_sex_determination | 0.85737396 |
| 113 | MP0001970_abnormal_pain_threshold | 0.85253253 |
| 114 | MP0002572_abnormal_emotion/affect_behav | 0.82554801 |
| 115 | MP0004085_abnormal_heartbeat | 0.82061873 |
| 116 | MP0009250_abnormal_appendicular_skeleto | 0.82024586 |
| 117 | MP0002249_abnormal_larynx_morphology | 0.81735671 |
| 118 | MP0002063_abnormal_learning/memory/cond | 0.81542007 |
| 119 | MP0002272_abnormal_nervous_system | 0.81433820 |
| 120 | MP0009745_abnormal_behavioral_response | 0.81122482 |
| 121 | MP0003755_abnormal_palate_morphology | 0.80959799 |
| 122 | MP0002733_abnormal_thermal_nociception | 0.80653603 |
| 123 | MP0002928_abnormal_bile_duct | 0.79952221 |
| 124 | MP0001440_abnormal_grooming_behavior | 0.79554235 |
| 125 | MP0001177_atelectasis | 0.79079464 |
| 126 | MP0000647_abnormal_sebaceous_gland | 0.78073729 |
| 127 | MP0003119_abnormal_digestive_system | 0.77808219 |
| 128 | MP0002085_abnormal_embryonic_tissue | 0.77375406 |
| 129 | MP0000350_abnormal_cell_proliferation | 0.75825523 |
| 130 | MP0009384_cardiac_valve_regurgitation | 0.74191480 |
| 131 | MP0003943_abnormal_hepatobiliary_system | 0.73942816 |
| 132 | MP0003935_abnormal_craniofacial_develop | 0.72952062 |
| 133 | MP0002233_abnormal_nose_morphology | 0.72897040 |
| 134 | MP0004270_analgesia | 0.71422519 |
| 135 | MP0002152_abnormal_brain_morphology | 0.71022026 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Congenital stationary night blindness (HP:0007642) | 7.14977035 |
| 2 | Attenuation of retinal blood vessels (HP:0007843) | 3.40208567 |
| 3 | Drooling (HP:0002307) | 3.29540401 |
| 4 | Medial flaring of the eyebrow (HP:0010747) | 3.24365443 |
| 5 | True hermaphroditism (HP:0010459) | 3.15960835 |
| 6 | Gait imbalance (HP:0002141) | 3.12406564 |
| 7 | Congenital primary aphakia (HP:0007707) | 3.11023263 |
| 8 | Abnormality of the columella (HP:0009929) | 3.04192226 |
| 9 | Abnormality of the labia minora (HP:0012880) | 3.02613956 |
| 10 | Pancreatic fibrosis (HP:0100732) | 2.98767958 |
| 11 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.95888905 |
| 12 | Hyperventilation (HP:0002883) | 2.95660024 |
| 13 | Excessive salivation (HP:0003781) | 2.95130018 |
| 14 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.92206045 |
| 15 | Birth length less than 3rd percentile (HP:0003561) | 2.92135906 |
| 16 | Nephrogenic diabetes insipidus (HP:0009806) | 2.91379699 |
| 17 | Nephronophthisis (HP:0000090) | 2.82388309 |
| 18 | Decreased central vision (HP:0007663) | 2.72149576 |
| 19 | Cortical dysplasia (HP:0002539) | 2.68913864 |
| 20 | Broad-based gait (HP:0002136) | 2.62093112 |
| 21 | Selective tooth agenesis (HP:0001592) | 2.58125423 |
| 22 | Poor coordination (HP:0002370) | 2.55626103 |
| 23 | Patellar aplasia (HP:0006443) | 2.49670602 |
| 24 | Genital tract atresia (HP:0001827) | 2.48602829 |
| 25 | Focal motor seizures (HP:0011153) | 2.47266357 |
| 26 | Abnormality of the renal medulla (HP:0100957) | 2.45948178 |
| 27 | Genetic anticipation (HP:0003743) | 2.44728479 |
| 28 | Long nose (HP:0003189) | 2.41626966 |
| 29 | Vaginal atresia (HP:0000148) | 2.39672431 |
| 30 | Preaxial hand polydactyly (HP:0001177) | 2.36110050 |
| 31 | Hepatoblastoma (HP:0002884) | 2.30868000 |
| 32 | Short middle phalanx of the 5th finger (HP:0004220) | 2.30525174 |
| 33 | Colon cancer (HP:0003003) | 2.29928650 |
| 34 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.28409285 |
| 35 | Lissencephaly (HP:0001339) | 2.28320593 |
| 36 | Specific learning disability (HP:0001328) | 2.27782827 |
| 37 | Atonic seizures (HP:0010819) | 2.27227959 |
| 38 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.26240248 |
| 39 | Supernumerary spleens (HP:0009799) | 2.26082368 |
| 40 | Exotropia (HP:0000577) | 2.22358428 |
| 41 | Renal cortical cysts (HP:0000803) | 2.19901760 |
| 42 | Embryonal renal neoplasm (HP:0011794) | 2.19388332 |
| 43 | Abnormality of the renal cortex (HP:0011035) | 2.17107634 |
| 44 | Cystic liver disease (HP:0006706) | 2.14512229 |
| 45 | Gaze-evoked nystagmus (HP:0000640) | 2.14126718 |
| 46 | Progressive cerebellar ataxia (HP:0002073) | 2.12557402 |
| 47 | Febrile seizures (HP:0002373) | 2.11362922 |
| 48 | Septo-optic dysplasia (HP:0100842) | 2.11103783 |
| 49 | Mixed hearing impairment (HP:0000410) | 2.10278830 |
| 50 | Pachygyria (HP:0001302) | 2.10218741 |
| 51 | Flat capital femoral epiphysis (HP:0003370) | 2.09273866 |
| 52 | Volvulus (HP:0002580) | 2.07984000 |
| 53 | Abnormal sex determination (HP:0012244) | 2.07479388 |
| 54 | Sex reversal (HP:0012245) | 2.07479388 |
| 55 | Median cleft lip (HP:0000161) | 2.07009350 |
| 56 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.05817886 |
| 57 | Pigmentary retinal degeneration (HP:0001146) | 2.05397172 |
| 58 | Postaxial foot polydactyly (HP:0001830) | 2.03175363 |
| 59 | Focal seizures (HP:0007359) | 2.03046953 |
| 60 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.02537400 |
| 61 | Pancreatic cysts (HP:0001737) | 2.02110414 |
| 62 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.01864487 |
| 63 | Papillary thyroid carcinoma (HP:0002895) | 2.01081497 |
| 64 | Renal dysplasia (HP:0000110) | 2.00085559 |
| 65 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.99788904 |
| 66 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.98617511 |
| 67 | Abnormal hair whorl (HP:0010721) | 1.97071592 |
| 68 | Chorioretinal atrophy (HP:0000533) | 1.96957205 |
| 69 | Morphological abnormality of the middle ear (HP:0008609) | 1.94481707 |
| 70 | Oligodactyly (hands) (HP:0001180) | 1.94233493 |
| 71 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.93508297 |
| 72 | Postaxial hand polydactyly (HP:0001162) | 1.93220903 |
| 73 | Pendular nystagmus (HP:0012043) | 1.93093514 |
| 74 | Protruding tongue (HP:0010808) | 1.93076096 |
| 75 | Epileptic encephalopathy (HP:0200134) | 1.92855698 |
| 76 | Abnormality of the preputium (HP:0100587) | 1.91192449 |
| 77 | Hemiparesis (HP:0001269) | 1.91073286 |
| 78 | Abnormality of the renal collecting system (HP:0004742) | 1.89369391 |
| 79 | Sclerocornea (HP:0000647) | 1.87865206 |
| 80 | Slow-growing hair (HP:0002217) | 1.87383122 |
| 81 | Abnormality of hair growth rate (HP:0011363) | 1.87383122 |
| 82 | Short foot (HP:0001773) | 1.87029471 |
| 83 | Type II lissencephaly (HP:0007260) | 1.85592848 |
| 84 | Progressive inability to walk (HP:0002505) | 1.83927355 |
| 85 | Abnormality of chromosome segregation (HP:0002916) | 1.83869571 |
| 86 | Abnormal lung lobation (HP:0002101) | 1.83508089 |
| 87 | Chromsome breakage (HP:0040012) | 1.83506338 |
| 88 | Short tibia (HP:0005736) | 1.81734910 |
| 89 | Dyschromatopsia (HP:0007641) | 1.81195608 |
| 90 | Hypoplastic left heart (HP:0004383) | 1.80801702 |
| 91 | Meckel diverticulum (HP:0002245) | 1.79857088 |
| 92 | Aqueductal stenosis (HP:0002410) | 1.79101899 |
| 93 | Cutaneous finger syndactyly (HP:0010554) | 1.78957747 |
| 94 | Chronic hepatic failure (HP:0100626) | 1.78887704 |
| 95 | Intestinal atresia (HP:0011100) | 1.78044583 |
| 96 | Type II diabetes mellitus (HP:0005978) | 1.78005532 |
| 97 | Inability to walk (HP:0002540) | 1.77824206 |
| 98 | Midline defect of the nose (HP:0004122) | 1.77472202 |
| 99 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.77392317 |
| 100 | Abnormality of the incisor (HP:0000676) | 1.77269832 |
| 101 | Lip pit (HP:0100267) | 1.76907545 |
| 102 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.76735220 |
| 103 | Agitation (HP:0000713) | 1.76254956 |
| 104 | Renal hypoplasia (HP:0000089) | 1.76135619 |
| 105 | Medulloblastoma (HP:0002885) | 1.75440450 |
| 106 | Aganglionic megacolon (HP:0002251) | 1.75232557 |
| 107 | Abnormality of midbrain morphology (HP:0002418) | 1.75179432 |
| 108 | Molar tooth sign on MRI (HP:0002419) | 1.75179432 |
| 109 | Abnormality of the septum pellucidum (HP:0007375) | 1.74843345 |
| 110 | Abnormal number of incisors (HP:0011064) | 1.74595408 |
| 111 | Photophobia (HP:0000613) | 1.74541057 |
| 112 | Abnormality of the ileum (HP:0001549) | 1.74534256 |
| 113 | Rib fusion (HP:0000902) | 1.73627237 |
| 114 | Male pseudohermaphroditism (HP:0000037) | 1.73100088 |
| 115 | Cutaneous syndactyly (HP:0012725) | 1.71851478 |
| 116 | Absent speech (HP:0001344) | 1.71791715 |
| 117 | Hyperglycinemia (HP:0002154) | 1.71053067 |
| 118 | Intellectual disability, moderate (HP:0002342) | 1.70580140 |
| 119 | Increased corneal curvature (HP:0100692) | 1.70493911 |
| 120 | Keratoconus (HP:0000563) | 1.70493911 |
| 121 | Adrenal hypoplasia (HP:0000835) | 1.70411095 |
| 122 | Abnormality of the lacrimal duct (HP:0011481) | 1.69947416 |
| 123 | Abnormality of incisor morphology (HP:0011063) | 1.69823551 |
| 124 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.69693283 |
| 125 | Polymicrogyria (HP:0002126) | 1.69522288 |
| 126 | Type I transferrin isoform profile (HP:0003642) | 1.69024908 |
| 127 | Hypothermia (HP:0002045) | 1.68879990 |
| 128 | Abnormality of the nasolacrimal system (HP:0000614) | 1.68391746 |
| 129 | Tubulointerstitial nephritis (HP:0001970) | 1.67579845 |
| 130 | Abnormality of chromosome stability (HP:0003220) | 1.67092240 |
| 131 | Choroideremia (HP:0001139) | 1.66935117 |
| 132 | Absent septum pellucidum (HP:0001331) | 1.66231583 |
| 133 | Narrow forehead (HP:0000341) | 1.65501330 |
| 134 | Scrotal hypoplasia (HP:0000046) | 1.63745784 |
| 135 | Abnormality of the corticospinal tract (HP:0002492) | 1.63560189 |
| 136 | Labial hypoplasia (HP:0000066) | 1.63521601 |
| 137 | Impulsivity (HP:0100710) | 1.62990459 |
| 138 | Anencephaly (HP:0002323) | 1.62634446 |
| 139 | Small hand (HP:0200055) | 1.62489281 |
| 140 | Micropenis (HP:0000054) | 1.62122602 |
| 141 | Nasolacrimal duct obstruction (HP:0000579) | 1.61814018 |
| 142 | Broad foot (HP:0001769) | 1.61804261 |
| 143 | Dialeptic seizures (HP:0011146) | 1.60287238 |
| 144 | Growth hormone deficiency (HP:0000824) | 1.60208511 |
| 145 | Decreased testicular size (HP:0008734) | 1.60026382 |
| 146 | Retinal dysplasia (HP:0007973) | 1.60020271 |
| 147 | Broad alveolar ridges (HP:0000187) | 1.59848913 |
| 148 | Pelvic girdle muscle weakness (HP:0003749) | 1.59749807 |
| 149 | Vitreoretinal degeneration (HP:0000655) | 1.59402462 |
| 150 | Neoplasm of the adrenal cortex (HP:0100641) | 1.59286816 |
| 151 | Optic nerve hypoplasia (HP:0000609) | 1.59050177 |
| 152 | Fair hair (HP:0002286) | 1.57713065 |
| 153 | Methylmalonic acidemia (HP:0002912) | 1.56810355 |
| 154 | Astigmatism (HP:0000483) | 1.56642691 |
| 155 | Cerebellar dysplasia (HP:0007033) | 1.55533689 |
| 156 | Occipital encephalocele (HP:0002085) | 1.55461863 |
| 157 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.55242912 |
| 158 | Short 4th metacarpal (HP:0010044) | 1.55242912 |
| 159 | Tented upper lip vermilion (HP:0010804) | 1.54177421 |
| 160 | Dandy-Walker malformation (HP:0001305) | 1.53742013 |
| 161 | Anophthalmia (HP:0000528) | 1.53089403 |
| 162 | Congenital hepatic fibrosis (HP:0002612) | 1.52744589 |
| 163 | Hyperglycinuria (HP:0003108) | 1.52050026 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CCNB1 | 3.31216637 |
| 2 | SRPK1 | 3.18498149 |
| 3 | MKNK2 | 2.89662595 |
| 4 | NEK1 | 2.79402302 |
| 5 | CDC7 | 2.60587272 |
| 6 | TNIK | 2.37968438 |
| 7 | ZAK | 2.27649755 |
| 8 | MKNK1 | 2.25862286 |
| 9 | CASK | 2.25406621 |
| 10 | MAPK13 | 2.22281104 |
| 11 | NEK2 | 2.21213459 |
| 12 | NEK6 | 2.02131696 |
| 13 | CDK3 | 1.95606290 |
| 14 | NTRK3 | 1.82072202 |
| 15 | TRIM28 | 1.78021916 |
| 16 | BRD4 | 1.77465722 |
| 17 | AKT3 | 1.72835083 |
| 18 | YES1 | 1.69084961 |
| 19 | STK39 | 1.59685419 |
| 20 | MAP2K7 | 1.59185992 |
| 21 | BUB1 | 1.53721961 |
| 22 | WEE1 | 1.49653985 |
| 23 | PLK3 | 1.48542958 |
| 24 | CDK8 | 1.47404246 |
| 25 | MAP3K4 | 1.46972253 |
| 26 | MAP4K2 | 1.46558886 |
| 27 | WNK4 | 1.46340280 |
| 28 | TTK | 1.44696473 |
| 29 | PLK4 | 1.44230467 |
| 30 | PINK1 | 1.43261897 |
| 31 | DYRK3 | 1.42199634 |
| 32 | EPHA4 | 1.40653009 |
| 33 | PNCK | 1.38995811 |
| 34 | VRK1 | 1.38740684 |
| 35 | EIF2AK3 | 1.38341240 |
| 36 | CHEK2 | 1.36719886 |
| 37 | NTRK2 | 1.33881932 |
| 38 | ERBB3 | 1.32802744 |
| 39 | LATS1 | 1.23432509 |
| 40 | ATR | 1.21917052 |
| 41 | TLK1 | 1.21345339 |
| 42 | FRK | 1.20896408 |
| 43 | PLK1 | 1.16739806 |
| 44 | GRK1 | 1.15356494 |
| 45 | PRPF4B | 1.14727572 |
| 46 | PAK3 | 1.14380965 |
| 47 | SIK3 | 1.12640764 |
| 48 | BCR | 1.12542214 |
| 49 | MARK1 | 1.12209606 |
| 50 | SGK2 | 1.11841691 |
| 51 | BMPR1B | 1.06641816 |
| 52 | PBK | 1.05475925 |
| 53 | DYRK2 | 1.04892941 |
| 54 | EIF2AK2 | 1.03987754 |
| 55 | SIK2 | 1.03083086 |
| 56 | RPS6KA4 | 1.01665448 |
| 57 | MAP2K4 | 1.01417884 |
| 58 | INSRR | 0.99945686 |
| 59 | CSNK1G1 | 0.97565000 |
| 60 | STK38L | 0.97011889 |
| 61 | MAPK7 | 0.95997231 |
| 62 | CAMKK2 | 0.92716468 |
| 63 | MAP3K12 | 0.91231065 |
| 64 | OXSR1 | 0.91201908 |
| 65 | CSNK1A1L | 0.90995540 |
| 66 | NUAK1 | 0.90204076 |
| 67 | PRKCG | 0.90073420 |
| 68 | PIK3CA | 0.89481639 |
| 69 | OBSCN | 0.89187097 |
| 70 | DYRK1A | 0.89046695 |
| 71 | UHMK1 | 0.86712895 |
| 72 | CDK19 | 0.83780137 |
| 73 | TXK | 0.83660198 |
| 74 | AURKB | 0.83284935 |
| 75 | RPS6KA5 | 0.83242992 |
| 76 | AURKA | 0.82685910 |
| 77 | NTRK1 | 0.81429103 |
| 78 | BRAF | 0.80975031 |
| 79 | FGFR2 | 0.80104366 |
| 80 | IRAK1 | 0.79608877 |
| 81 | ACVR1B | 0.76731440 |
| 82 | IRAK2 | 0.76308608 |
| 83 | STK16 | 0.75690384 |
| 84 | CHEK1 | 0.75318651 |
| 85 | CAMK1G | 0.74532133 |
| 86 | WNK1 | 0.74503264 |
| 87 | WNK3 | 0.73829340 |
| 88 | ADRBK2 | 0.73227478 |
| 89 | STK3 | 0.71226709 |
| 90 | BRSK2 | 0.70585292 |
| 91 | TAOK2 | 0.70266603 |
| 92 | EPHB2 | 0.67899312 |
| 93 | RPS6KB1 | 0.67651744 |
| 94 | SGK494 | 0.67266237 |
| 95 | SGK223 | 0.67266237 |
| 96 | ATM | 0.66162323 |
| 97 | FLT3 | 0.65813997 |
| 98 | CDK7 | 0.64634487 |
| 99 | TGFBR1 | 0.62810726 |
| 100 | PLK2 | 0.62695516 |
| 101 | CDK1 | 0.62340309 |
| 102 | CDK5 | 0.62206922 |
| 103 | DAPK2 | 0.61622471 |
| 104 | ERBB2 | 0.58759281 |
| 105 | DYRK1B | 0.58624336 |
| 106 | PAK6 | 0.57617640 |
| 107 | BMPR2 | 0.56915572 |
| 108 | TSSK6 | 0.56051067 |
| 109 | PRKD3 | 0.55365364 |
| 110 | NLK | 0.55298921 |
| 111 | CAMK2A | 0.54720778 |
| 112 | TYRO3 | 0.50175445 |
| 113 | PRKCI | 0.49946856 |
| 114 | MELK | 0.49566662 |
| 115 | EPHA3 | 0.48752292 |
| 116 | CDK2 | 0.47995057 |
| 117 | PRKCE | 0.47770194 |
| 118 | NEK9 | 0.47676145 |
| 119 | CSNK1G3 | 0.47261718 |
| 120 | STK11 | 0.46690535 |
| 121 | PHKG2 | 0.46183293 |
| 122 | PHKG1 | 0.46183293 |
| 123 | CSNK2A1 | 0.45693985 |
| 124 | CSNK1E | 0.44785916 |
| 125 | SGK1 | 0.44584001 |
| 126 | PRKAA1 | 0.43132371 |
| 127 | GSK3B | 0.42360998 |
| 128 | MAP3K6 | 0.42225561 |
| 129 | TIE1 | 0.41819505 |
| 130 | ADRBK1 | 0.41534006 |
| 131 | MINK1 | 0.41430914 |
| 132 | TNK2 | 0.39940966 |
| 133 | MAPK14 | 0.39314851 |
| 134 | PKN1 | 0.38291243 |
| 135 | MARK3 | 0.37780221 |
| 136 | CSNK2A2 | 0.37755475 |
| 137 | CSNK1G2 | 0.36865666 |
| 138 | CAMK4 | 0.36465733 |
| 139 | CAMK2B | 0.35840460 |
| 140 | KSR1 | 0.35533766 |
| 141 | MAPK12 | 0.35199155 |
| 142 | PRKACA | 0.34565535 |
| 143 | CAMK1D | 0.34180824 |
| 144 | MAPK8 | 0.33930165 |
| 145 | CSNK1D | 0.33872595 |
| 146 | FGFR1 | 0.33491490 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phototransduction_Homo sapiens_hsa04744 | 5.26064097 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 2.45138748 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 2.40984756 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.37972222 |
| 5 | Spliceosome_Homo sapiens_hsa03040 | 2.37093238 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.24387229 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.23318907 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.21247185 |
| 9 | Cell cycle_Homo sapiens_hsa04110 | 2.12749061 |
| 10 | DNA replication_Homo sapiens_hsa03030 | 2.11185825 |
| 11 | Nicotine addiction_Homo sapiens_hsa05033 | 2.08927259 |
| 12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.01911333 |
| 13 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.00386547 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.92948833 |
| 15 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.92489016 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 1.85043256 |
| 17 | RNA transport_Homo sapiens_hsa03013 | 1.84651891 |
| 18 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.80317859 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.77633823 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.74396837 |
| 21 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.62627984 |
| 22 | Protein export_Homo sapiens_hsa03060 | 1.56487090 |
| 23 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.51233491 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.50724362 |
| 25 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.35909715 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.29621482 |
| 27 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.29015979 |
| 28 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.28853026 |
| 29 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.27920129 |
| 30 | Proteasome_Homo sapiens_hsa03050 | 1.26341930 |
| 31 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.22914177 |
| 32 | Circadian rhythm_Homo sapiens_hsa04710 | 1.21955241 |
| 33 | Olfactory transduction_Homo sapiens_hsa04740 | 1.19790116 |
| 34 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.18606400 |
| 35 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.18307528 |
| 36 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.17865474 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.14700342 |
| 38 | Alcoholism_Homo sapiens_hsa05034 | 1.13362412 |
| 39 | Morphine addiction_Homo sapiens_hsa05032 | 1.11933293 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.11293612 |
| 41 | GABAergic synapse_Homo sapiens_hsa04727 | 1.08956595 |
| 42 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.06890210 |
| 43 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.04940892 |
| 44 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.03228716 |
| 45 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.02601243 |
| 46 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.02549923 |
| 47 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.00904917 |
| 48 | Circadian entrainment_Homo sapiens_hsa04713 | 0.99390584 |
| 49 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.98163597 |
| 50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.97924561 |
| 51 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.97551149 |
| 52 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.95967564 |
| 53 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.94407071 |
| 54 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.92213154 |
| 55 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.91739321 |
| 56 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.90264369 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89625138 |
| 58 | Long-term potentiation_Homo sapiens_hsa04720 | 0.88287027 |
| 59 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.86509283 |
| 60 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.84766529 |
| 61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.84428347 |
| 62 | Taste transduction_Homo sapiens_hsa04742 | 0.83911362 |
| 63 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.81259284 |
| 64 | Insulin secretion_Homo sapiens_hsa04911 | 0.79898552 |
| 65 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.79501717 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.76754044 |
| 67 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.75995539 |
| 68 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.75869065 |
| 69 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.73719279 |
| 70 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.73710575 |
| 71 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.73488373 |
| 72 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.71131902 |
| 73 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.70189856 |
| 74 | Peroxisome_Homo sapiens_hsa04146 | 0.69339025 |
| 75 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.68182104 |
| 76 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.67457879 |
| 77 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.66454497 |
| 78 | ABC transporters_Homo sapiens_hsa02010 | 0.66431343 |
| 79 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.65177260 |
| 80 | Axon guidance_Homo sapiens_hsa04360 | 0.64013323 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.63398866 |
| 82 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.62922991 |
| 83 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.62802685 |
| 84 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62016322 |
| 85 | Endometrial cancer_Homo sapiens_hsa05213 | 0.61607576 |
| 86 | Colorectal cancer_Homo sapiens_hsa05210 | 0.60960997 |
| 87 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.60483151 |
| 88 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.60186630 |
| 89 | Melanoma_Homo sapiens_hsa05218 | 0.59643567 |
| 90 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.58272915 |
| 91 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.57685526 |
| 92 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.57330658 |
| 93 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.57311916 |
| 94 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.56852977 |
| 95 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.56659379 |
| 96 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.56324595 |
| 97 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.56041208 |
| 98 | Renin secretion_Homo sapiens_hsa04924 | 0.55296738 |
| 99 | HTLV-I infection_Homo sapiens_hsa05166 | 0.55143086 |
| 100 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.55036508 |
| 101 | Salivary secretion_Homo sapiens_hsa04970 | 0.54236255 |
| 102 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.53425000 |
| 103 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.53368783 |
| 104 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.53030011 |
| 105 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.52855126 |
| 106 | Huntingtons disease_Homo sapiens_hsa05016 | 0.51560837 |
| 107 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.51551837 |
| 108 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51077301 |
| 109 | Tight junction_Homo sapiens_hsa04530 | 0.50800727 |
| 110 | Adherens junction_Homo sapiens_hsa04520 | 0.50619205 |
| 111 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.50178804 |
| 112 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.49706832 |
| 113 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.49500154 |
| 114 | Gap junction_Homo sapiens_hsa04540 | 0.49364200 |
| 115 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.48165149 |
| 116 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.48041629 |
| 117 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.46876691 |
| 118 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.46831689 |
| 119 | Prostate cancer_Homo sapiens_hsa05215 | 0.46153225 |
| 120 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.45659432 |
| 121 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.45161030 |
| 122 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.44513651 |
| 123 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.43919961 |
| 124 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.43773850 |
| 125 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.43710353 |
| 126 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43466184 |
| 127 | Long-term depression_Homo sapiens_hsa04730 | 0.42874242 |
| 128 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.41914521 |
| 129 | Melanogenesis_Homo sapiens_hsa04916 | 0.41326174 |
| 130 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41253742 |
| 131 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.40031204 |
| 132 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39357056 |
| 133 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.38812427 |
| 134 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.37825490 |
| 135 | Pathways in cancer_Homo sapiens_hsa05200 | 0.36952911 |
| 136 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.36448392 |
| 137 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.35701769 |
| 138 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.35151494 |
| 139 | Hepatitis B_Homo sapiens_hsa05161 | 0.35056641 |
| 140 | Allograft rejection_Homo sapiens_hsa05330 | 0.34718800 |
| 141 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.34599865 |
| 142 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.34477014 |
| 143 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.34412968 |
| 144 | Cocaine addiction_Homo sapiens_hsa05030 | 0.33216458 |
| 145 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.31707668 |
| 146 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.31554388 |

