Rank | Gene Set | Z-score |
---|---|---|
1 | pre-miRNA processing (GO:0031054) | 5.28124168 |
2 | regulation of translational termination (GO:0006449) | 4.62964026 |
3 | mannose metabolic process (GO:0006013) | 4.59520524 |
4 | nuclear pore complex assembly (GO:0051292) | 4.58126833 |
5 | nuclear pore organization (GO:0006999) | 4.43362828 |
6 | negative regulation of histone methylation (GO:0031061) | 4.41805934 |
7 | regulation of translational fidelity (GO:0006450) | 4.31328389 |
8 | apoptotic process involved in morphogenesis (GO:0060561) | 4.20847649 |
9 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 4.10590409 |
10 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.10321124 |
11 | activation of Rac GTPase activity (GO:0032863) | 3.92706267 |
12 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.83266963 |
13 | histone H4-K12 acetylation (GO:0043983) | 3.79757391 |
14 | DNA unwinding involved in DNA replication (GO:0006268) | 3.73097615 |
15 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.72529523 |
16 | mitotic sister chromatid cohesion (GO:0007064) | 3.71195716 |
17 | semaphorin-plexin signaling pathway (GO:0071526) | 3.68437653 |
18 | adherens junction assembly (GO:0034333) | 3.64237650 |
19 | protein localization to kinetochore (GO:0034501) | 3.63981907 |
20 | NLS-bearing protein import into nucleus (GO:0006607) | 3.62573067 |
21 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.62040849 |
22 | IMP biosynthetic process (GO:0006188) | 3.56372542 |
23 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.56304457 |
24 | focal adhesion assembly (GO:0048041) | 3.54520260 |
25 | cell-substrate adherens junction assembly (GO:0007045) | 3.54520260 |
26 | DNA duplex unwinding (GO:0032508) | 3.50760592 |
27 | peptidyl-lysine dimethylation (GO:0018027) | 3.49701003 |
28 | DNA geometric change (GO:0032392) | 3.48891596 |
29 | snRNA metabolic process (GO:0016073) | 3.47897586 |
30 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.46688480 |
31 | positive regulation of histone deacetylation (GO:0031065) | 3.43204236 |
32 | histone H4-K5 acetylation (GO:0043981) | 3.39003218 |
33 | histone H4-K8 acetylation (GO:0043982) | 3.39003218 |
34 | pore complex assembly (GO:0046931) | 3.36999933 |
35 | histone H2A monoubiquitination (GO:0035518) | 3.34809104 |
36 | heterochromatin organization (GO:0070828) | 3.34272280 |
37 | nucleobase biosynthetic process (GO:0046112) | 3.32920292 |
38 | histone H4-K16 acetylation (GO:0043984) | 3.32601721 |
39 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.32147107 |
40 | chromatin silencing (GO:0006342) | 3.32091436 |
41 | mitotic nuclear envelope disassembly (GO:0007077) | 3.29885918 |
42 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.29402886 |
43 | peptidyl-arginine methylation (GO:0018216) | 3.26163985 |
44 | peptidyl-arginine N-methylation (GO:0035246) | 3.26163985 |
45 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.24580546 |
46 | negative regulation of RNA splicing (GO:0033119) | 3.24256796 |
47 | regulation of histone H3-K9 methylation (GO:0051570) | 3.23963453 |
48 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.20329872 |
49 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.18591831 |
50 | nuclear envelope disassembly (GO:0051081) | 3.17565887 |
51 | membrane disassembly (GO:0030397) | 3.17565887 |
52 | histone H3-K4 methylation (GO:0051568) | 3.17323772 |
53 | maternal placenta development (GO:0001893) | 3.17298726 |
54 | dosage compensation (GO:0007549) | 3.16643088 |
55 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.16207115 |
56 | regulation of gene silencing by miRNA (GO:0060964) | 3.16207115 |
57 | regulation of gene silencing by RNA (GO:0060966) | 3.16207115 |
58 | regulation of ARF GTPase activity (GO:0032312) | 3.08332081 |
59 | negative regulation of mRNA metabolic process (GO:1903312) | 3.07608796 |
60 | regulation of RNA export from nucleus (GO:0046831) | 3.06442928 |
61 | negative regulation of mRNA processing (GO:0050686) | 3.03741158 |
62 | activation of MAPKKK activity (GO:0000185) | 3.01994151 |
63 | histone H3-K4 trimethylation (GO:0080182) | 3.01253609 |
64 | regulation of DNA damage checkpoint (GO:2000001) | 3.00799344 |
65 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.00456304 |
66 | sister chromatid segregation (GO:0000819) | 2.99859211 |
67 | snRNA processing (GO:0016180) | 2.98539254 |
68 | stress granule assembly (GO:0034063) | 2.98039158 |
69 | establishment of apical/basal cell polarity (GO:0035089) | 2.97728104 |
70 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.97708883 |
71 | regulation of chromatin binding (GO:0035561) | 2.96419019 |
72 | mitotic sister chromatid segregation (GO:0000070) | 2.95998962 |
73 | histone H4 acetylation (GO:0043967) | 2.92775288 |
74 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.92634098 |
75 | modulation by virus of host process (GO:0019054) | 2.90953712 |
76 | determination of adult lifespan (GO:0008340) | 2.90764971 |
77 | locomotory exploration behavior (GO:0035641) | 2.89802890 |
78 | negative regulation of viral release from host cell (GO:1902187) | 2.89318377 |
79 | modulation by symbiont of host cellular process (GO:0044068) | 2.88249347 |
80 | cell-substrate junction assembly (GO:0007044) | 2.87977770 |
81 | positive regulation of RNA splicing (GO:0033120) | 2.87850792 |
82 | histone lysine methylation (GO:0034968) | 2.87412478 |
83 | mRNA splice site selection (GO:0006376) | 2.86759054 |
84 | protein localization to chromosome, centromeric region (GO:0071459) | 2.86698706 |
85 | RNA stabilization (GO:0043489) | 2.84784903 |
86 | mRNA stabilization (GO:0048255) | 2.84784903 |
87 | histone methylation (GO:0016571) | 2.84277708 |
88 | proline biosynthetic process (GO:0006561) | 2.83071385 |
89 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.81795509 |
90 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 2.81576464 |
91 | gene silencing (GO:0016458) | 2.80730159 |
92 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 2.80251627 |
93 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.80169346 |
94 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.80015788 |
95 | apoptotic process involved in development (GO:1902742) | 2.79576379 |
96 | negative regulation of histone modification (GO:0031057) | 2.78896627 |
97 | regulation of mitotic spindle organization (GO:0060236) | 2.78647505 |
98 | histone lysine demethylation (GO:0070076) | 2.78087047 |
99 | cellular protein complex localization (GO:0034629) | 2.77718778 |
100 | IMP metabolic process (GO:0046040) | 2.77418493 |
101 | negative regulation of cell size (GO:0045792) | 2.77163167 |
102 | COPI coating of Golgi vesicle (GO:0048205) | 2.77145580 |
103 | Golgi transport vesicle coating (GO:0048200) | 2.77145580 |
104 | regulation of DNA endoreduplication (GO:0032875) | 2.76672677 |
105 | regulation of early endosome to late endosome transport (GO:2000641) | 2.75768906 |
106 | protein retention in ER lumen (GO:0006621) | 2.75277932 |
107 | purine nucleobase biosynthetic process (GO:0009113) | 2.73374659 |
108 | histone demethylation (GO:0016577) | 2.73250656 |
109 | regulation of translational elongation (GO:0006448) | 2.72868289 |
110 | mitotic G1/S transition checkpoint (GO:0044819) | 2.72531162 |
111 | histone H3-K36 demethylation (GO:0070544) | 2.72479634 |
112 | corticosteroid receptor signaling pathway (GO:0031958) | 2.71477141 |
113 | mRNA transport (GO:0051028) | 2.70859790 |
114 | peptidyl-lysine trimethylation (GO:0018023) | 2.70547430 |
115 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.70063264 |
116 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.69513566 |
117 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.69460133 |
118 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.69338909 |
119 | regulation of intracellular estrogen receptor signaling pathway (GO:0033146) | 2.68988435 |
120 | mitotic chromosome condensation (GO:0007076) | 2.68237478 |
121 | negative regulation of chromatin modification (GO:1903309) | 2.67584358 |
122 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.67495740 |
123 | chromatin assembly (GO:0031497) | 2.67347158 |
124 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.67026171 |
125 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.66939084 |
126 | peptidyl-lysine methylation (GO:0018022) | 2.66664660 |
127 | G1 DNA damage checkpoint (GO:0044783) | 2.66377823 |
128 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.66369765 |
129 | negative regulation of cell killing (GO:0031342) | 2.66369765 |
130 | histone H4 deacetylation (GO:0070933) | 2.66222178 |
131 | protein localization to endosome (GO:0036010) | 2.64580775 |
132 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.63954658 |
133 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.63954658 |
134 | DNA replication initiation (GO:0006270) | 2.62587958 |
135 | histone arginine methylation (GO:0034969) | 2.62501642 |
136 | regulation of histone H3-K27 methylation (GO:0061085) | 2.62301724 |
137 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059) | 2.60831183 |
138 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.60708769 |
139 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.60318718 |
140 | nucleosome disassembly (GO:0006337) | 2.59819576 |
141 | protein-DNA complex disassembly (GO:0032986) | 2.59819576 |
142 | chromosome condensation (GO:0030261) | 2.59353589 |
143 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.57104378 |
144 | regulation of histone methylation (GO:0031060) | 2.56947797 |
145 | positive regulation of chromosome segregation (GO:0051984) | 2.56909821 |
146 | ear development (GO:0043583) | 2.55910870 |
147 | protein export from nucleus (GO:0006611) | 2.55638965 |
148 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.55586866 |
149 | positive regulation of protein deacetylation (GO:0090312) | 2.55436861 |
150 | thymic T cell selection (GO:0045061) | 2.53362179 |
151 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.53195348 |
152 | NIK/NF-kappaB signaling (GO:0038061) | 2.52768542 |
153 | protein complex localization (GO:0031503) | 2.52764844 |
154 | protein demethylation (GO:0006482) | 2.52422758 |
155 | protein dealkylation (GO:0008214) | 2.52422758 |
156 | cellular response to virus (GO:0098586) | 2.51775272 |
157 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.51336731 |
158 | atrioventricular valve morphogenesis (GO:0003181) | 2.50896334 |
159 | histone H3 deacetylation (GO:0070932) | 2.49443385 |
160 | rRNA transcription (GO:0009303) | 2.48843338 |
161 | response to muramyl dipeptide (GO:0032495) | 2.45609945 |
162 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.45583516 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.26318889 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.31555672 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 3.87831767 |
4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.76530279 |
5 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.78335459 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.75521644 |
7 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.65144496 |
8 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.60134830 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.58730930 |
10 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.57608167 |
11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.52141492 |
12 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.41933211 |
13 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.34984767 |
14 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.17595063 |
15 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 2.16734489 |
16 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.11464400 |
17 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.07374472 |
18 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.03951114 |
19 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.97564677 |
20 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.97462750 |
21 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.94444833 |
22 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.91785337 |
23 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.84163951 |
24 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.80500247 |
25 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.79006403 |
26 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.72986739 |
27 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.72494279 |
28 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.71582902 |
29 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.69754542 |
30 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.69573835 |
31 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.69032285 |
32 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.69023582 |
33 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.67690373 |
34 | * KDM5A_27292631_Chip-Seq_BREAST_Human | 1.66464221 |
35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.66338964 |
36 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.63210608 |
37 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.62692347 |
38 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.62312256 |
39 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.61695826 |
40 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.59530012 |
41 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.55032776 |
42 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.52482485 |
43 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.51918287 |
44 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.50759514 |
45 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.49562073 |
46 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.49539580 |
47 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.48138623 |
48 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.47563626 |
49 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.46411534 |
50 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.42985420 |
51 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.42799373 |
52 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.42789404 |
53 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.42720991 |
54 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.42235614 |
55 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.42163046 |
56 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.40434855 |
57 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.39403848 |
58 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.38645592 |
59 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.37793581 |
60 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.37616890 |
61 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.37613088 |
62 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.33514068 |
63 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.32900096 |
64 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.31722221 |
65 | * ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.29886742 |
66 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.28772255 |
67 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.27772386 |
68 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.26854096 |
69 | MAF_26560356_Chip-Seq_TH1_Human | 1.26492724 |
70 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.26275987 |
71 | KDM2B_26808549_Chip-Seq_K562_Human | 1.24393446 |
72 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.24293584 |
73 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.24181864 |
74 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.22630138 |
75 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.21980382 |
76 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.21216903 |
77 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.20954302 |
78 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.20617149 |
79 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.18933418 |
80 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.18928738 |
81 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.18786652 |
82 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.18352386 |
83 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.18049409 |
84 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.17860998 |
85 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.17464669 |
86 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.16697123 |
87 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.16692407 |
88 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.16644293 |
89 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.16115264 |
90 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.15279997 |
91 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.14589996 |
92 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.14167616 |
93 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.12410957 |
94 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.12235630 |
95 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.11229267 |
96 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.11055226 |
97 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.11009271 |
98 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.10561911 |
99 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.08273823 |
100 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.08263400 |
101 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.07974783 |
102 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.07973262 |
103 | * P68_20966046_ChIP-Seq_HELA_Human | 1.07946509 |
104 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.07714925 |
105 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.06794598 |
106 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.06242473 |
107 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.06197054 |
108 | * RARA_24833708_ChIP-Seq_LIVER_Mouse | 1.06133385 |
109 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.05725129 |
110 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.05719160 |
111 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.04616865 |
112 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.03896540 |
113 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.03809872 |
114 | MYB_26560356_Chip-Seq_TH1_Human | 1.03763920 |
115 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.02583719 |
116 | * BCL6_27268052_Chip-Seq_Bcells_Human | 1.01702192 |
117 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.00823065 |
118 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.00195276 |
119 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.00171088 |
120 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.00070226 |
121 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99929923 |
122 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.99655216 |
123 | MAF_26560356_Chip-Seq_TH2_Human | 0.99498224 |
124 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.99332049 |
125 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.99320145 |
126 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.99300857 |
127 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.99179352 |
128 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.98518165 |
129 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.98126801 |
130 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.97826060 |
131 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.96209351 |
132 | ATF3_27146783_Chip-Seq_COLON_Human | 0.95233533 |
133 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.94979330 |
134 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 0.94691057 |
135 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93415911 |
136 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.92948531 |
137 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.91890151 |
138 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.90607002 |
139 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90381020 |
140 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.87923273 |
141 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 0.87731944 |
142 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.87205194 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003111_abnormal_nucleus_morphology | 3.51610319 |
2 | MP0003693_abnormal_embryo_hatching | 3.39286366 |
3 | MP0000569_abnormal_digit_pigmentation | 3.22369539 |
4 | MP0004859_abnormal_synaptic_plasticity | 3.19491063 |
5 | MP0010094_abnormal_chromosome_stability | 3.15971471 |
6 | MP0003123_paternal_imprinting | 2.83418778 |
7 | MP0005451_abnormal_body_composition | 2.83369466 |
8 | MP0004957_abnormal_blastocyst_morpholog | 2.79454518 |
9 | MP0003787_abnormal_imprinting | 2.72144748 |
10 | MP0008057_abnormal_DNA_replication | 2.70996942 |
11 | MP0000678_abnormal_parathyroid_gland | 2.69881879 |
12 | MP0003077_abnormal_cell_cycle | 2.68550074 |
13 | MP0001348_abnormal_lacrimal_gland | 2.57084008 |
14 | MP0002249_abnormal_larynx_morphology | 2.44722014 |
15 | MP0010352_gastrointestinal_tract_polyps | 2.38931878 |
16 | MP0008260_abnormal_autophagy | 2.38113140 |
17 | MP0005076_abnormal_cell_differentiation | 2.37015263 |
18 | MP0004185_abnormal_adipocyte_glucose | 2.25372160 |
19 | MP0001730_embryonic_growth_arrest | 2.24771509 |
20 | MP0008877_abnormal_DNA_methylation | 2.24292738 |
21 | MP0010307_abnormal_tumor_latency | 2.22160008 |
22 | MP0000350_abnormal_cell_proliferation | 2.06161257 |
23 | MP0002396_abnormal_hematopoietic_system | 2.04677138 |
24 | MP0005058_abnormal_lysosome_morphology | 2.02668300 |
25 | MP0008961_abnormal_basal_metabolism | 1.96565026 |
26 | MP0003121_genomic_imprinting | 1.95379425 |
27 | MP0001672_abnormal_embryogenesis/_devel | 1.83054661 |
28 | MP0005380_embryogenesis_phenotype | 1.83054661 |
29 | MP0004197_abnormal_fetal_growth/weight/ | 1.78649424 |
30 | MP0000537_abnormal_urethra_morphology | 1.78591742 |
31 | MP0003453_abnormal_keratinocyte_physiol | 1.78234578 |
32 | MP0008058_abnormal_DNA_repair | 1.76796829 |
33 | MP0003984_embryonic_growth_retardation | 1.75573620 |
34 | MP0003705_abnormal_hypodermis_morpholog | 1.73821851 |
35 | MP0002088_abnormal_embryonic_growth/wei | 1.70757720 |
36 | MP0002084_abnormal_developmental_patter | 1.69274490 |
37 | MP0003763_abnormal_thymus_physiology | 1.64022403 |
38 | MP0001873_stomach_inflammation | 1.63109654 |
39 | MP0002080_prenatal_lethality | 1.61105652 |
40 | MP0004233_abnormal_muscle_weight | 1.60228849 |
41 | MP0001697_abnormal_embryo_size | 1.59806790 |
42 | MP0002085_abnormal_embryonic_tissue | 1.57420710 |
43 | MP0002086_abnormal_extraembryonic_tissu | 1.56534628 |
44 | MP0003890_abnormal_embryonic-extraembry | 1.56323181 |
45 | MP0004808_abnormal_hematopoietic_stem | 1.55747934 |
46 | MP0005623_abnormal_meninges_morphology | 1.54878551 |
47 | MP0009333_abnormal_splenocyte_physiolog | 1.52694388 |
48 | MP0000703_abnormal_thymus_morphology | 1.47666370 |
49 | MP0005409_darkened_coat_color | 1.46380349 |
50 | MP0003635_abnormal_synaptic_transmissio | 1.41877817 |
51 | MP0003436_decreased_susceptibility_to | 1.40006638 |
52 | MP0003283_abnormal_digestive_organ | 1.38775787 |
53 | MP0009672_abnormal_birth_weight | 1.38368572 |
54 | MP0008007_abnormal_cellular_replicative | 1.35129469 |
55 | MP0002653_abnormal_ependyma_morphology | 1.32765750 |
56 | MP0003119_abnormal_digestive_system | 1.28286193 |
57 | MP0005666_abnormal_adipose_tissue | 1.28209193 |
58 | MP0002796_impaired_skin_barrier | 1.27304881 |
59 | MP0010030_abnormal_orbit_morphology | 1.27223634 |
60 | MP0009703_decreased_birth_body | 1.24631183 |
61 | MP0005501_abnormal_skin_physiology | 1.23619769 |
62 | MP0003091_abnormal_cell_migration | 1.22224001 |
63 | MP0001849_ear_inflammation | 1.20241407 |
64 | MP0004381_abnormal_hair_follicle | 1.19963822 |
65 | MP0000003_abnormal_adipose_tissue | 1.19134164 |
66 | MP0004947_skin_inflammation | 1.17109751 |
67 | MP0003172_abnormal_lysosome_physiology | 1.16713566 |
68 | MP0003300_gastrointestinal_ulcer | 1.15285253 |
69 | MP0003303_peritoneal_inflammation | 1.14375559 |
70 | MP0009053_abnormal_anal_canal | 1.13207335 |
71 | MP0000428_abnormal_craniofacial_morphol | 1.12332443 |
72 | MP0001346_abnormal_lacrimal_gland | 1.11916878 |
73 | MP0001661_extended_life_span | 1.11712156 |
74 | MP0000313_abnormal_cell_death | 1.10417361 |
75 | MP0010234_abnormal_vibrissa_follicle | 1.10099034 |
76 | MP0003566_abnormal_cell_adhesion | 1.08670001 |
77 | MP0006292_abnormal_olfactory_placode | 1.07627596 |
78 | MP0000858_altered_metastatic_potential | 1.05598340 |
79 | MP0003942_abnormal_urinary_system | 1.04654565 |
80 | MP0008932_abnormal_embryonic_tissue | 1.04435751 |
81 | MP0009278_abnormal_bone_marrow | 1.04410360 |
82 | MP0002398_abnormal_bone_marrow | 1.03395076 |
83 | MP0005621_abnormal_cell_physiology | 1.02339805 |
84 | MP0009840_abnormal_foam_cell | 1.01214695 |
85 | MP0000733_abnormal_muscle_development | 1.00239171 |
86 | MP0004811_abnormal_neuron_physiology | 0.99791954 |
87 | MP0010630_abnormal_cardiac_muscle | 0.99407827 |
88 | MP0008770_decreased_survivor_rate | 0.98532263 |
89 | MP0005257_abnormal_intraocular_pressure | 0.98207612 |
90 | MP0009384_cardiac_valve_regurgitation | 0.96194498 |
91 | MP0008569_lethality_at_weaning | 0.94978963 |
92 | MP0005384_cellular_phenotype | 0.94644430 |
93 | MP0002089_abnormal_postnatal_growth/wei | 0.92916216 |
94 | MP0003861_abnormal_nervous_system | 0.91950973 |
95 | MP0002063_abnormal_learning/memory/cond | 0.91662096 |
96 | MP0002019_abnormal_tumor_incidence | 0.90031726 |
97 | MP0005397_hematopoietic_system_phenotyp | 0.89146407 |
98 | MP0001545_abnormal_hematopoietic_system | 0.89146407 |
99 | MP0000371_diluted_coat_color | 0.87614170 |
100 | MP0004264_abnormal_extraembryonic_tissu | 0.87111048 |
101 | MP0002254_reproductive_system_inflammat | 0.86507124 |
102 | MP0000490_abnormal_crypts_of | 0.85983203 |
103 | MP0002722_abnormal_immune_system | 0.85857716 |
104 | MP0002822_catalepsy | 0.85213064 |
105 | MP0005394_taste/olfaction_phenotype | 0.85031416 |
106 | MP0005499_abnormal_olfactory_system | 0.85031416 |
107 | MP0009046_muscle_twitch | 0.84965510 |
108 | MP0009931_abnormal_skin_appearance | 0.84869404 |
109 | MP0002909_abnormal_adrenal_gland | 0.84681390 |
110 | MP0002060_abnormal_skin_morphology | 0.84035423 |
111 | MP0003115_abnormal_respiratory_system | 0.83514263 |
112 | MP0000013_abnormal_adipose_tissue | 0.82674993 |
113 | MP0002092_abnormal_eye_morphology | 0.80757410 |
114 | MP0001293_anophthalmia | 0.80575622 |
115 | MP0003786_premature_aging | 0.79836990 |
116 | MP0009780_abnormal_chondrocyte_physiolo | 0.79154880 |
117 | MP0002116_abnormal_craniofacial_bone | 0.78819454 |
118 | MP0001216_abnormal_epidermal_layer | 0.77719892 |
119 | MP0003122_maternal_imprinting | 0.77318271 |
120 | MP0002925_abnormal_cardiovascular_devel | 0.76633248 |
121 | MP0000579_abnormal_nail_morphology | 0.75884079 |
122 | MP0003866_abnormal_defecation | 0.75375067 |
123 | MP0003567_abnormal_fetal_cardiomyocyte | 0.74620575 |
124 | MP0000467_abnormal_esophagus_morphology | 0.74527409 |
125 | MP0000759_abnormal_skeletal_muscle | 0.74148974 |
126 | MP0002111_abnormal_tail_morphology | 0.74104341 |
127 | MP0002269_muscular_atrophy | 0.74027307 |
128 | MP0000681_abnormal_thyroid_gland | 0.73831766 |
129 | MP0000685_abnormal_immune_system | 0.73642804 |
130 | MP0002152_abnormal_brain_morphology | 0.73564527 |
131 | MP0003045_fibrosis | 0.73478735 |
132 | MP0000566_synostosis | 0.72801344 |
133 | MP0002932_abnormal_joint_morphology | 0.72341450 |
134 | MP0000266_abnormal_heart_morphology | 0.70596590 |
135 | MP0000689_abnormal_spleen_morphology | 0.70259933 |
136 | MP0004510_myositis | 0.70112258 |
137 | MP0002877_abnormal_melanocyte_morpholog | 0.69174194 |
138 | MP0005375_adipose_tissue_phenotype | 0.68710104 |
139 | MP0010768_mortality/aging | 0.65648880 |
140 | MP0010769_abnormal_survival | 0.65396446 |
141 | MP0003935_abnormal_craniofacial_develop | 0.64874451 |
142 | MP0004858_abnormal_nervous_system | 0.64340054 |
143 | MP0002210_abnormal_sex_determination | 0.63981096 |
144 | MP0000358_abnormal_cell_content/ | 0.63356961 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 4.52916970 |
2 | Astrocytoma (HP:0009592) | 3.70321415 |
3 | Abnormality of the astrocytes (HP:0100707) | 3.70321415 |
4 | Ulnar bowing (HP:0003031) | 3.46517227 |
5 | Hyperacusis (HP:0010780) | 3.44565679 |
6 | Obstructive sleep apnea (HP:0002870) | 3.28486785 |
7 | Abnormality of the lower motor neuron (HP:0002366) | 3.25344351 |
8 | Volvulus (HP:0002580) | 3.08471129 |
9 | Glioma (HP:0009733) | 3.00104195 |
10 | Abnormality of the aortic arch (HP:0012303) | 2.96600724 |
11 | Broad distal phalanx of finger (HP:0009836) | 2.92525280 |
12 | Broad face (HP:0000283) | 2.90704720 |
13 | Abnormality of the fingertips (HP:0001211) | 2.87116137 |
14 | Neoplasm of the heart (HP:0100544) | 2.86214963 |
15 | Medulloblastoma (HP:0002885) | 2.79339040 |
16 | Thin bony cortex (HP:0002753) | 2.77457665 |
17 | Long palpebral fissure (HP:0000637) | 2.72953187 |
18 | Increased nuchal translucency (HP:0010880) | 2.64691630 |
19 | Pointed chin (HP:0000307) | 2.58899857 |
20 | Neoplasm of striated muscle (HP:0009728) | 2.57369526 |
21 | Heterotopia (HP:0002282) | 2.55644043 |
22 | Urethral obstruction (HP:0000796) | 2.55478052 |
23 | Disproportionate tall stature (HP:0001519) | 2.55105176 |
24 | Elfin facies (HP:0004428) | 2.54101391 |
25 | Prominent nose (HP:0000448) | 2.52152275 |
26 | Abnormality of the labia minora (HP:0012880) | 2.49917478 |
27 | Basal cell carcinoma (HP:0002671) | 2.49104133 |
28 | Neoplasm of the oral cavity (HP:0100649) | 2.48085602 |
29 | Anal stenosis (HP:0002025) | 2.44630200 |
30 | Stridor (HP:0010307) | 2.43537349 |
31 | Atelectasis (HP:0100750) | 2.40538796 |
32 | Hand muscle atrophy (HP:0009130) | 2.39149389 |
33 | Achilles tendon contracture (HP:0001771) | 2.39006429 |
34 | Impaired smooth pursuit (HP:0007772) | 2.36851304 |
35 | Dysmetric saccades (HP:0000641) | 2.36748472 |
36 | Increased connective tissue (HP:0009025) | 2.35923851 |
37 | Insomnia (HP:0100785) | 2.34666532 |
38 | Distal lower limb amyotrophy (HP:0008944) | 2.34637812 |
39 | Fragile skin (HP:0001030) | 2.34245372 |
40 | Renovascular hypertension (HP:0100817) | 2.33717820 |
41 | Obsessive-compulsive behavior (HP:0000722) | 2.33176535 |
42 | Truncus arteriosus (HP:0001660) | 2.33125607 |
43 | Progressive muscle weakness (HP:0003323) | 2.33108290 |
44 | Abnormality of the thoracic spine (HP:0100711) | 2.32847694 |
45 | Long eyelashes (HP:0000527) | 2.32697626 |
46 | Cerebral aneurysm (HP:0004944) | 2.32529335 |
47 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.31348472 |
48 | Short 4th metacarpal (HP:0010044) | 2.31348472 |
49 | Urinary urgency (HP:0000012) | 2.30728064 |
50 | Distal upper limb amyotrophy (HP:0007149) | 2.29081574 |
51 | Upper limb amyotrophy (HP:0009129) | 2.29081574 |
52 | Spinal muscular atrophy (HP:0007269) | 2.27814282 |
53 | Patellar dislocation (HP:0002999) | 2.24568729 |
54 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.18183767 |
55 | Turricephaly (HP:0000262) | 2.15311223 |
56 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.14488254 |
57 | Proximal placement of thumb (HP:0009623) | 2.13359631 |
58 | Abnormality of the Achilles tendon (HP:0005109) | 2.11873580 |
59 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.11164937 |
60 | Renal duplication (HP:0000075) | 2.11042170 |
61 | Flat acetabular roof (HP:0003180) | 2.10879485 |
62 | Deviation of the thumb (HP:0009603) | 2.10720083 |
63 | Mitral regurgitation (HP:0001653) | 2.10494600 |
64 | Progressive external ophthalmoplegia (HP:0000590) | 2.10442466 |
65 | Bowed forearm bones (HP:0003956) | 2.08089115 |
66 | Bowing of the arm (HP:0006488) | 2.08089115 |
67 | Macroorchidism (HP:0000053) | 2.07098547 |
68 | Metaphyseal cupping (HP:0003021) | 2.06360541 |
69 | Resting tremor (HP:0002322) | 2.06234299 |
70 | Abnormal number of incisors (HP:0011064) | 2.04162094 |
71 | Overriding aorta (HP:0002623) | 2.02907259 |
72 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.02769393 |
73 | Abnormality of the radial head (HP:0003995) | 2.01176614 |
74 | Hemiplegia (HP:0002301) | 1.99854417 |
75 | High anterior hairline (HP:0009890) | 1.96858991 |
76 | Skin tags (HP:0010609) | 1.96846533 |
77 | Cafe-au-lait spot (HP:0000957) | 1.95984542 |
78 | Broad palm (HP:0001169) | 1.95414635 |
79 | Short nail (HP:0001799) | 1.93822495 |
80 | Neoplasm of the adrenal cortex (HP:0100641) | 1.93174272 |
81 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.91992976 |
82 | Hyperthyroidism (HP:0000836) | 1.90989177 |
83 | Nasal polyposis (HP:0100582) | 1.90953255 |
84 | Attention deficit hyperactivity disorder (HP:0007018) | 1.90111170 |
85 | Self-mutilation (HP:0000742) | 1.89461260 |
86 | Bowel incontinence (HP:0002607) | 1.89190237 |
87 | Abnormality of the columella (HP:0009929) | 1.88185810 |
88 | Annular pancreas (HP:0001734) | 1.87918061 |
89 | Colitis (HP:0002583) | 1.87576521 |
90 | Squamous cell carcinoma (HP:0002860) | 1.86295676 |
91 | Sandal gap (HP:0001852) | 1.84923843 |
92 | Selective tooth agenesis (HP:0001592) | 1.84698204 |
93 | Bowel diverticulosis (HP:0005222) | 1.84481951 |
94 | Persistence of primary teeth (HP:0006335) | 1.84104568 |
95 | Thoracic kyphosis (HP:0002942) | 1.83809086 |
96 | Rhabdomyosarcoma (HP:0002859) | 1.82939068 |
97 | Flared metaphyses (HP:0003015) | 1.82840822 |
98 | Ankle clonus (HP:0011448) | 1.82399164 |
99 | Biconcave vertebral bodies (HP:0004586) | 1.81992651 |
100 | Hypopigmentation of the fundus (HP:0007894) | 1.81883298 |
101 | Vertebral arch anomaly (HP:0008438) | 1.81294976 |
102 | Angiofibromas (HP:0010615) | 1.80414192 |
103 | Adenoma sebaceum (HP:0009720) | 1.80414192 |
104 | Narrow palate (HP:0000189) | 1.79847202 |
105 | Precocious puberty (HP:0000826) | 1.79756554 |
106 | Ragged-red muscle fibers (HP:0003200) | 1.78955607 |
107 | Lymphangioma (HP:0100764) | 1.78480298 |
108 | Spina bifida occulta (HP:0003298) | 1.77711112 |
109 | Abnormal large intestine physiology (HP:0012700) | 1.77630543 |
110 | Premature skin wrinkling (HP:0100678) | 1.76631499 |
111 | Reticulocytosis (HP:0001923) | 1.76551245 |
112 | Amaurosis fugax (HP:0100576) | 1.76070859 |
113 | Spinal cord lesions (HP:0100561) | 1.75294832 |
114 | Syringomyelia (HP:0003396) | 1.75294832 |
115 | Hypertensive crisis (HP:0100735) | 1.74741972 |
116 | Abnormal vertebral ossification (HP:0100569) | 1.73223374 |
117 | Thin ribs (HP:0000883) | 1.72146159 |
118 | Genetic anticipation (HP:0003743) | 1.72075337 |
119 | Broad thumb (HP:0011304) | 1.71826297 |
120 | Hypoparathyroidism (HP:0000829) | 1.70844618 |
121 | Truncal obesity (HP:0001956) | 1.70643595 |
122 | Trismus (HP:0000211) | 1.70498943 |
123 | Ankyloglossia (HP:0010296) | 1.70335587 |
124 | Trigonocephaly (HP:0000243) | 1.70210557 |
125 | Pelvic girdle muscle weakness (HP:0003749) | 1.70116402 |
126 | Visual hallucinations (HP:0002367) | 1.69944224 |
127 | Supernumerary ribs (HP:0005815) | 1.69660780 |
128 | Seborrheic dermatitis (HP:0001051) | 1.69439109 |
129 | Shallow orbits (HP:0000586) | 1.69051292 |
130 | Abnormality of the diencephalon (HP:0010662) | 1.68113618 |
131 | Aneurysm (HP:0002617) | 1.68078359 |
132 | Microvesicular hepatic steatosis (HP:0001414) | 1.67922906 |
133 | Skull defect (HP:0001362) | 1.67898043 |
134 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.67852700 |
135 | Abnormality of the nasal mucosa (HP:0000433) | 1.67636968 |
136 | Missing ribs (HP:0000921) | 1.67175393 |
137 | Spastic gait (HP:0002064) | 1.67050581 |
138 | Difficulty climbing stairs (HP:0003551) | 1.65626794 |
139 | Pseudobulbar signs (HP:0002200) | 1.65590656 |
140 | Chromsome breakage (HP:0040012) | 1.64511424 |
141 | Hemorrhage of the eye (HP:0011885) | 1.64143890 |
142 | Abnormality of the humeroradial joint (HP:0100744) | 1.62937057 |
143 | Lower limb amyotrophy (HP:0007210) | 1.62925735 |
144 | Emphysema (HP:0002097) | 1.62793178 |
145 | Arnold-Chiari malformation (HP:0002308) | 1.62208326 |
146 | Germ cell neoplasia (HP:0100728) | 1.62146442 |
147 | Sacral dimple (HP:0000960) | 1.61827945 |
148 | Bronchomalacia (HP:0002780) | 1.61686857 |
149 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.61608329 |
150 | Gastrointestinal carcinoma (HP:0002672) | 1.61608329 |
151 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.61242716 |
152 | Impulsivity (HP:0100710) | 1.61182587 |
153 | Increased density of long bones (HP:0006392) | 1.61009639 |
154 | Broad phalanges of the hand (HP:0009768) | 1.60833835 |
155 | Protrusio acetabuli (HP:0003179) | 1.60614192 |
156 | Smooth philtrum (HP:0000319) | 1.60416657 |
157 | 11 pairs of ribs (HP:0000878) | 1.58692477 |
158 | Preauricular skin tag (HP:0000384) | 1.58578191 |
159 | Facial hemangioma (HP:0000329) | 1.58529969 |
160 | Cervical subluxation (HP:0003308) | 1.58151747 |
161 | J-shaped sella turcica (HP:0002680) | 1.57828430 |
162 | High pitched voice (HP:0001620) | 1.57574188 |
163 | Genu recurvatum (HP:0002816) | 1.57277920 |
164 | Sparse lateral eyebrow (HP:0005338) | 1.56806419 |
165 | Atrophic scars (HP:0001075) | 1.56512979 |
166 | Malignant neoplasm of the central nervous system (HP:0100836) | 1.56255662 |
167 | Deep palmar crease (HP:0006191) | 1.56188553 |
168 | Abnormality of the carotid arteries (HP:0005344) | 1.55972398 |
169 | Focal seizures (HP:0007359) | 1.55785358 |
170 | Dislocated radial head (HP:0003083) | 1.54950130 |
171 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.54168411 |
172 | Birth length less than 3rd percentile (HP:0003561) | 1.53472085 |
173 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.53373600 |
174 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.53324898 |
175 | Fibroma (HP:0010614) | 1.52812439 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SMG1 | 4.44158542 |
2 | CDK12 | 4.05838052 |
3 | EEF2K | 3.08782180 |
4 | CDC7 | 2.78971630 |
5 | PRPF4B | 2.78806427 |
6 | RIPK1 | 2.77182440 |
7 | TRIB3 | 2.52383209 |
8 | PKN2 | 2.47497249 |
9 | SIK2 | 2.39553547 |
10 | NEK2 | 2.36735930 |
11 | TAOK2 | 2.34274639 |
12 | IRAK3 | 2.31135886 |
13 | ALK | 2.23674342 |
14 | MAP3K10 | 2.18956189 |
15 | BRD4 | 2.05360133 |
16 | TSSK6 | 2.02942936 |
17 | INSRR | 1.97351171 |
18 | ERN1 | 1.96442503 |
19 | NEK1 | 1.87274745 |
20 | NME2 | 1.84151288 |
21 | MAP3K9 | 1.71761861 |
22 | PRKD3 | 1.64963126 |
23 | MAP4K1 | 1.58310202 |
24 | PNCK | 1.56229922 |
25 | MAP3K7 | 1.52044444 |
26 | SCYL2 | 1.50975368 |
27 | CAMK1G | 1.50473212 |
28 | CDK4 | 1.48994911 |
29 | TAOK1 | 1.47202505 |
30 | ICK | 1.44478376 |
31 | NTRK3 | 1.44357181 |
32 | MTOR | 1.44304616 |
33 | FGFR4 | 1.39881995 |
34 | MAP2K3 | 1.35567398 |
35 | CHEK1 | 1.34168727 |
36 | STK38 | 1.32360891 |
37 | ATR | 1.30658905 |
38 | TYRO3 | 1.29871956 |
39 | WEE1 | 1.26919331 |
40 | CAMK1D | 1.25232825 |
41 | TTK | 1.22290200 |
42 | MARK2 | 1.20189687 |
43 | MST1R | 1.17911898 |
44 | MAP3K11 | 1.09200299 |
45 | NME1 | 1.03588732 |
46 | PASK | 1.02514246 |
47 | MAP3K4 | 1.01061144 |
48 | CDC42BPA | 1.00310913 |
49 | CDK2 | 1.00256006 |
50 | DAPK2 | 1.00152717 |
51 | IRAK2 | 0.98800580 |
52 | TTN | 0.96330085 |
53 | RPS6KB2 | 0.96231442 |
54 | DAPK1 | 0.95899328 |
55 | CAMKK1 | 0.93805556 |
56 | HIPK2 | 0.89510976 |
57 | CDK7 | 0.88283992 |
58 | IRAK4 | 0.87137777 |
59 | RIPK4 | 0.86075963 |
60 | MAPK11 | 0.85543125 |
61 | ATM | 0.84800772 |
62 | PAK6 | 0.82778321 |
63 | CDK6 | 0.82674760 |
64 | GRK6 | 0.82656427 |
65 | PLK1 | 0.82481129 |
66 | CSNK1E | 0.79593294 |
67 | MAP2K6 | 0.78506057 |
68 | CHEK2 | 0.78015025 |
69 | PTK6 | 0.77389816 |
70 | KSR2 | 0.76037527 |
71 | RPS6KL1 | 0.75191310 |
72 | RPS6KC1 | 0.75191310 |
73 | BRSK1 | 0.74477576 |
74 | PRKCH | 0.73300967 |
75 | PRKDC | 0.72781332 |
76 | CAMK4 | 0.72003209 |
77 | ZAP70 | 0.71498357 |
78 | PDGFRA | 0.70824526 |
79 | CDK9 | 0.70783350 |
80 | SIK1 | 0.70562627 |
81 | MAP3K8 | 0.70522467 |
82 | SGK3 | 0.70498816 |
83 | MKNK2 | 0.70408067 |
84 | PTK2 | 0.70058053 |
85 | PDPK1 | 0.67582362 |
86 | CDK1 | 0.67550639 |
87 | MAPK15 | 0.65846489 |
88 | NTRK2 | 0.64960296 |
89 | STK10 | 0.63749868 |
90 | AURKA | 0.63341943 |
91 | PRKCI | 0.62982953 |
92 | MAP3K1 | 0.62413124 |
93 | PRKD2 | 0.62053617 |
94 | LATS2 | 0.61089882 |
95 | * MAPK14 | 0.60787995 |
96 | MAPK10 | 0.59954980 |
97 | KSR1 | 0.59602896 |
98 | SRPK1 | 0.59491613 |
99 | * GSK3B | 0.58328776 |
100 | CSNK1D | 0.57988768 |
101 | AURKB | 0.57603012 |
102 | PAK2 | 0.57147033 |
103 | MAP3K14 | 0.56912778 |
104 | EPHA2 | 0.56591777 |
105 | MAP2K2 | 0.56467938 |
106 | RPS6KA6 | 0.55079376 |
107 | MAP3K6 | 0.54967234 |
108 | MAP3K13 | 0.54074582 |
109 | BMX | 0.53987436 |
110 | TBK1 | 0.53836100 |
111 | JAK3 | 0.53772700 |
112 | SIK3 | 0.53496131 |
113 | RPS6KA2 | 0.53219155 |
114 | STK11 | 0.53199170 |
115 | FGFR1 | 0.52446230 |
116 | CAMK1 | 0.51951438 |
117 | MAPK8 | 0.51828336 |
118 | AKT3 | 0.51315110 |
119 | EPHB1 | 0.50046342 |
120 | PIM2 | 0.48586845 |
121 | PLK3 | 0.48175796 |
122 | FES | 0.47871570 |
123 | RPS6KA1 | 0.47777221 |
124 | BUB1 | 0.46403196 |
125 | PIM1 | 0.44863748 |
126 | RPS6KA3 | 0.44554806 |
127 | MARK3 | 0.43600832 |
128 | EPHA4 | 0.43444275 |
129 | TNK2 | 0.43186023 |
130 | CHUK | 0.42781834 |
131 | ARAF | 0.41935283 |
132 | RAF1 | 0.41671772 |
133 | BRAF | 0.41619771 |
134 | MELK | 0.41373975 |
135 | MAPK1 | 0.40313694 |
136 | RPS6KA4 | 0.38890949 |
137 | HCK | 0.38634749 |
138 | PAK4 | 0.38556856 |
139 | TYK2 | 0.38515963 |
140 | MAPK12 | 0.38123179 |
141 | MAP3K3 | 0.37634319 |
142 | PDK1 | 0.35038817 |
143 | RET | 0.33655794 |
144 | BTK | 0.33610024 |
145 | CDK8 | 0.32304842 |
146 | AKT2 | 0.32290363 |
147 | LRRK2 | 0.31363216 |
148 | MET | 0.30322284 |
149 | AKT1 | 0.29777406 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.27769871 |
2 | RNA transport_Homo sapiens_hsa03013 | 2.12102977 |
3 | Other glycan degradation_Homo sapiens_hsa00511 | 2.07514521 |
4 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.06210017 |
5 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.02361685 |
6 | DNA replication_Homo sapiens_hsa03030 | 1.95865417 |
7 | Spliceosome_Homo sapiens_hsa03040 | 1.88900588 |
8 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.85368799 |
9 | Bladder cancer_Homo sapiens_hsa05219 | 1.85233812 |
10 | Mismatch repair_Homo sapiens_hsa03430 | 1.81349102 |
11 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.80338251 |
12 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.57997315 |
13 | Sulfur relay system_Homo sapiens_hsa04122 | 1.51112532 |
14 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.50856246 |
15 | Cell cycle_Homo sapiens_hsa04110 | 1.48687657 |
16 | Lysine degradation_Homo sapiens_hsa00310 | 1.46345134 |
17 | Long-term potentiation_Homo sapiens_hsa04720 | 1.44714035 |
18 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.42744794 |
19 | Olfactory transduction_Homo sapiens_hsa04740 | 1.42536047 |
20 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.36206623 |
21 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.31289159 |
22 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.31057373 |
23 | Base excision repair_Homo sapiens_hsa03410 | 1.30053208 |
24 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.28866597 |
25 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.27601049 |
26 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.20507685 |
27 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.19473205 |
28 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.19304596 |
29 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.17688643 |
30 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.15355055 |
31 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.14272090 |
32 | Insulin secretion_Homo sapiens_hsa04911 | 1.14129395 |
33 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.13302497 |
34 | Apoptosis_Homo sapiens_hsa04210 | 1.08240477 |
35 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.07494493 |
36 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.07332957 |
37 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.07215522 |
38 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.06975005 |
39 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.06914221 |
40 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.06776685 |
41 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.03926646 |
42 | Hepatitis C_Homo sapiens_hsa05160 | 1.03687081 |
43 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.02856797 |
44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.02480206 |
45 | Colorectal cancer_Homo sapiens_hsa05210 | 1.00619089 |
46 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.00464500 |
47 | Glioma_Homo sapiens_hsa05214 | 1.00206089 |
48 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.99099471 |
49 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.98575869 |
50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.97621003 |
51 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.97327464 |
52 | Endometrial cancer_Homo sapiens_hsa05213 | 0.95400813 |
53 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.95392251 |
54 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.94237147 |
55 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.94038124 |
56 | Prion diseases_Homo sapiens_hsa05020 | 0.94011915 |
57 | Influenza A_Homo sapiens_hsa05164 | 0.93434368 |
58 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.92851936 |
59 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.92312498 |
60 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.91153876 |
61 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.90825936 |
62 | HTLV-I infection_Homo sapiens_hsa05166 | 0.90638528 |
63 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.90388811 |
64 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.90212063 |
65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.90119416 |
66 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.89859315 |
67 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.89777427 |
68 | Circadian entrainment_Homo sapiens_hsa04713 | 0.89248763 |
69 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.87052509 |
70 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.85529905 |
71 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.84596044 |
72 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.83960943 |
73 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.83523775 |
74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.83240645 |
75 | Insulin resistance_Homo sapiens_hsa04931 | 0.82058561 |
76 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.81293270 |
77 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.80721588 |
78 | RNA degradation_Homo sapiens_hsa03018 | 0.79529529 |
79 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.78829922 |
80 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.78051934 |
81 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.77422852 |
82 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.76559740 |
83 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.76344985 |
84 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.76103127 |
85 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.75780179 |
86 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.75288222 |
87 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.75275932 |
88 | Galactose metabolism_Homo sapiens_hsa00052 | 0.74728717 |
89 | Adherens junction_Homo sapiens_hsa04520 | 0.74386575 |
90 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.73216007 |
91 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.73205014 |
92 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.72345572 |
93 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.70745012 |
94 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.70295748 |
95 | Focal adhesion_Homo sapiens_hsa04510 | 0.70264882 |
96 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.70254700 |
97 | Prostate cancer_Homo sapiens_hsa05215 | 0.70145580 |
98 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.69550535 |
99 | Morphine addiction_Homo sapiens_hsa05032 | 0.69223625 |
100 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.69023544 |
101 | Homologous recombination_Homo sapiens_hsa03440 | 0.68397800 |
102 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.68368454 |
103 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.67958986 |
104 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.65136184 |
105 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.64850146 |
106 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.64157344 |
107 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.64002454 |
108 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.63934304 |
109 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.63480426 |
110 | Measles_Homo sapiens_hsa05162 | 0.63372892 |
111 | Salivary secretion_Homo sapiens_hsa04970 | 0.63304919 |
112 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.62682624 |
113 | Thyroid cancer_Homo sapiens_hsa05216 | 0.62425901 |
114 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.61977652 |
115 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.61725557 |
116 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60528651 |
117 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.60333085 |
118 | Cocaine addiction_Homo sapiens_hsa05030 | 0.59678876 |
119 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.59614709 |
120 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.59300326 |
121 | Hepatitis B_Homo sapiens_hsa05161 | 0.58624228 |
122 | Gap junction_Homo sapiens_hsa04540 | 0.58331481 |
123 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.58255604 |
124 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.57896034 |
125 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.57322519 |
126 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.57314533 |
127 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.57289934 |
128 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.57043389 |
129 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.56696946 |
130 | Endocytosis_Homo sapiens_hsa04144 | 0.56301551 |
131 | Shigellosis_Homo sapiens_hsa05131 | 0.55879325 |
132 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.55710072 |
133 | GABAergic synapse_Homo sapiens_hsa04727 | 0.54875506 |
134 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.54192609 |
135 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.53488870 |
136 | Pathways in cancer_Homo sapiens_hsa05200 | 0.52337167 |
137 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.48052623 |
138 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.47765985 |
139 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.46158400 |
140 | Leishmaniasis_Homo sapiens_hsa05140 | 0.43741222 |