SNN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)6.10591356
2synaptic vesicle maturation (GO:0016188)5.56050008
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.25449868
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.22927789
5layer formation in cerebral cortex (GO:0021819)4.97812825
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.92749530
7synaptic vesicle exocytosis (GO:0016079)4.87184533
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.81200341
9regulation of synapse structural plasticity (GO:0051823)4.75996239
10vocalization behavior (GO:0071625)4.72183136
11regulation of glutamate receptor signaling pathway (GO:1900449)4.67020028
12exploration behavior (GO:0035640)4.61746476
13regulation of synaptic vesicle exocytosis (GO:2000300)4.48475608
14dendritic spine morphogenesis (GO:0060997)4.36925838
15glutamate secretion (GO:0014047)4.36087221
16synaptic vesicle docking involved in exocytosis (GO:0016081)4.32302629
17protein localization to synapse (GO:0035418)4.21590432
18regulation of long-term neuronal synaptic plasticity (GO:0048169)4.19138039
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.12812804
20regulation of neuronal synaptic plasticity (GO:0048168)4.07214370
21G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)4.05339997
22regulation of synaptic vesicle transport (GO:1902803)3.93696463
23regulation of dendritic spine morphogenesis (GO:0061001)3.92038378
24neurotransmitter secretion (GO:0007269)3.81066420
25neuron cell-cell adhesion (GO:0007158)3.75288804
26prepulse inhibition (GO:0060134)3.60825757
27neuron recognition (GO:0008038)3.59402222
28negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.54843590
29negative regulation of cell killing (GO:0031342)3.54843590
30sodium ion export (GO:0071436)3.53546682
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.53198171
32neuromuscular process controlling balance (GO:0050885)3.52074903
33proline transport (GO:0015824)3.51617313
34activation of protein kinase A activity (GO:0034199)3.51491807
35glutamate receptor signaling pathway (GO:0007215)3.49190131
36long-term memory (GO:0007616)3.48828889
37neuronal action potential propagation (GO:0019227)3.48580701
38regulation of excitatory postsynaptic membrane potential (GO:0060079)3.47012842
39positive regulation of synapse maturation (GO:0090129)3.45716271
40synaptic transmission, glutamatergic (GO:0035249)3.43683708
41neutrophil activation involved in immune response (GO:0002283)3.43084740
42axonal fasciculation (GO:0007413)3.42378682
43dendrite morphogenesis (GO:0048813)3.42127329
44regulation of ARF protein signal transduction (GO:0032012)3.40493341
45membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.39080736
46positive regulation by symbiont of host defense response (GO:0052509)3.38651439
47modulation by symbiont of host defense response (GO:0052031)3.38651439
48modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.38651439
49modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.38651439
50positive regulation by organism of defense response of other organism involved in symbiotic interact3.38651439
51modulation by symbiont of host immune response (GO:0052553)3.38651439
52positive regulation of membrane potential (GO:0045838)3.37224506
53neurotransmitter-gated ion channel clustering (GO:0072578)3.37099997
54cerebellar granule cell differentiation (GO:0021707)3.33134719
55regulation of synaptic plasticity (GO:0048167)3.31136680
56adenosine receptor signaling pathway (GO:0001973)3.30469887
57L-amino acid import (GO:0043092)3.29537916
58cellular potassium ion homeostasis (GO:0030007)3.27996256
59neuron-neuron synaptic transmission (GO:0007270)3.26054167
60macrophage activation involved in immune response (GO:0002281)3.25642156
61regulation of postsynaptic membrane potential (GO:0060078)3.25365521
62negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.23447367
63regulation of dendritic spine development (GO:0060998)3.21985342
64positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.20254527
65cell migration in hindbrain (GO:0021535)3.17402592
66positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.16636470
67auditory behavior (GO:0031223)3.13282878
68long-term synaptic potentiation (GO:0060291)3.10743357
69clathrin coat assembly (GO:0048268)3.10092705
70gamma-aminobutyric acid transport (GO:0015812)3.09381118
71establishment of nucleus localization (GO:0040023)3.08818591
72response to auditory stimulus (GO:0010996)3.05193679
73positive regulation of synaptic transmission, GABAergic (GO:0032230)3.04481840
74dendritic spine organization (GO:0097061)3.03786524
75vesicle transport along microtubule (GO:0047496)3.01915963
76positive regulation of mast cell activation (GO:0033005)3.00993822
77regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.00958817
78positive regulation of dendritic spine morphogenesis (GO:0061003)2.99970655
79synaptic vesicle endocytosis (GO:0048488)2.98056144
80cell communication by electrical coupling (GO:0010644)2.97812035
81regulation of synaptic transmission, glutamatergic (GO:0051966)2.97461294
82neuronal ion channel clustering (GO:0045161)2.95702983
83neurotransmitter transport (GO:0006836)2.91779269
84regulation of Rap GTPase activity (GO:0032317)2.90577187
85positive regulation of neurotransmitter secretion (GO:0001956)2.90176565
86transmission of nerve impulse (GO:0019226)2.89623642
87response to peptidoglycan (GO:0032494)2.89488481
88regulation of neurotransmitter secretion (GO:0046928)2.88495211
89positive regulation of dendritic spine development (GO:0060999)2.87841328
90dopamine receptor signaling pathway (GO:0007212)2.87589140
91cerebellar Purkinje cell differentiation (GO:0021702)2.87534594
92signal complex assembly (GO:0007172)2.86028770
93positive regulation of gamma-delta T cell activation (GO:0046645)2.85705832
94positive regulation of neurotransmitter transport (GO:0051590)2.84864102
95central nervous system projection neuron axonogenesis (GO:0021952)2.84045060
96regulation of vesicle fusion (GO:0031338)2.83381055
97positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.83176432
98cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.83006566
99negative regulation of erythrocyte differentiation (GO:0045647)2.82965877
100membrane depolarization (GO:0051899)2.82210953
101pyrimidine nucleobase catabolic process (GO:0006208)2.81456355
102positive regulation of cellular amide metabolic process (GO:0034250)2.81400330
103microglial cell activation (GO:0001774)2.80649384
104mating behavior (GO:0007617)2.77867212
105postsynaptic membrane organization (GO:0001941)2.77812212
106central nervous system myelination (GO:0022010)2.76060135
107axon ensheathment in central nervous system (GO:0032291)2.76060135
108regulation of T-helper 2 cell differentiation (GO:0045628)2.75773258
109nerve growth factor signaling pathway (GO:0038180)2.75519648
110presynaptic membrane organization (GO:0097090)2.75357947
111leukocyte migration involved in inflammatory response (GO:0002523)2.75211412
112negative regulation of microtubule polymerization (GO:0031115)2.75152323
113behavioral defense response (GO:0002209)2.75081579
114behavioral fear response (GO:0001662)2.75081579
115regulation of neurotransmitter levels (GO:0001505)2.74488592
116negative regulation of synaptic transmission, GABAergic (GO:0032229)2.74329760
117negative regulation of interleukin-12 production (GO:0032695)2.74106526
118innervation (GO:0060384)2.73409178
119cytoskeletal anchoring at plasma membrane (GO:0007016)2.72668438
120positive regulation of Rap GTPase activity (GO:0032854)2.72281665
121membrane depolarization during action potential (GO:0086010)2.72072321
122adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.71476371
123organelle transport along microtubule (GO:0072384)2.70352206
124intraspecies interaction between organisms (GO:0051703)2.70184592
125social behavior (GO:0035176)2.70184592
126regulation of neurotransmitter transport (GO:0051588)2.68844175
127synapse assembly (GO:0007416)2.68353955
128regulation of ARF GTPase activity (GO:0032312)2.68124488
129learning (GO:0007612)2.67213985
130amino acid import (GO:0043090)2.64649189
131detection of other organism (GO:0098543)2.54723833
132response to muramyl dipeptide (GO:0032495)2.53809191
133neutrophil activation (GO:0042119)2.51329419
134granulocyte activation (GO:0036230)2.49693712
135regulation of regulated secretory pathway (GO:1903305)2.48786610
136positive regulation of mast cell activation involved in immune response (GO:0033008)2.45757844
137positive regulation of mast cell degranulation (GO:0043306)2.45757844
138macrophage activation (GO:0042116)2.44889778
139antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.43305814
140positive regulation of type 2 immune response (GO:0002830)2.43211547
141cellular response to nerve growth factor stimulus (GO:1990090)2.41873696
142response to nerve growth factor (GO:1990089)2.41873696
143regulation of mast cell degranulation (GO:0043304)2.38490776
144regulation of voltage-gated calcium channel activity (GO:1901385)2.37249863
145myeloid cell activation involved in immune response (GO:0002275)2.34897700
146presynaptic membrane assembly (GO:0097105)2.34334907
147establishment of mitochondrion localization (GO:0051654)2.32505614
148neuromuscular process controlling posture (GO:0050884)2.29856388
149negative regulation of amino acid transport (GO:0051956)2.29823742
150potassium ion import (GO:0010107)2.29742290
151detection of bacterium (GO:0016045)2.29479021

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.94732025
2JARID2_20064375_ChIP-Seq_MESCs_Mouse2.98507219
3RARB_27405468_Chip-Seq_BRAIN_Mouse2.90402192
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.88303862
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.75305949
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.72642414
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.72642414
8THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.62661956
9DROSHA_22980978_ChIP-Seq_HELA_Human2.59830703
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.51747021
11IKZF1_21737484_ChIP-ChIP_HCT116_Human2.47332727
12* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.44683180
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.42755310
14EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.41643984
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38339863
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38064466
17REST_21632747_ChIP-Seq_MESCs_Mouse2.37988802
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.32682241
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.28182795
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26307990
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.24972294
22GBX2_23144817_ChIP-Seq_PC3_Human2.24244671
23BP1_19119308_ChIP-ChIP_Hs578T_Human2.20381911
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.18215330
25MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.02770089
26REST_18959480_ChIP-ChIP_MESCs_Mouse1.98637844
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.93441208
28AR_21572438_ChIP-Seq_LNCaP_Human1.85604853
29IRF8_21731497_ChIP-ChIP_J774_Mouse1.84398807
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.82635407
31WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.79691107
32KDM2B_26808549_Chip-Seq_SUP-B15_Human1.78143270
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77247736
34KDM2B_26808549_Chip-Seq_K562_Human1.70494148
35ZFP281_18757296_ChIP-ChIP_E14_Mouse1.69448188
36CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.60806128
37VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.57661537
38* IRF8_27001747_Chip-Seq_BMDM_Mouse1.55505512
39MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.55404973
40SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.54685576
41ZFP281_27345836_Chip-Seq_ESCs_Mouse1.49245213
42TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.48468165
43DNAJC2_21179169_ChIP-ChIP_NT2_Human1.47997354
44SMAD_19615063_ChIP-ChIP_OVARY_Human1.46785683
45* RING1B_27294783_Chip-Seq_ESCs_Mouse1.46282417
46* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.44586734
47KDM2B_26808549_Chip-Seq_DND41_Human1.44047056
48SPI1_23127762_ChIP-Seq_K562_Human1.42485381
49RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.41633162
50WT1_25993318_ChIP-Seq_PODOCYTE_Human1.39385322
51* GATA1_19941827_ChIP-Seq_MEL_Mouse1.36739918
52SCL_19346495_ChIP-Seq_HPC-7_Human1.36449555
53GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.34422897
54* RING1B_27294783_Chip-Seq_NPCs_Mouse1.32663549
55TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32457445
56KDM2B_26808549_Chip-Seq_JURKAT_Human1.30508926
57ERG_21242973_ChIP-ChIP_JURKAT_Human1.28210530
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.26887861
59DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.25442768
60STAT6_21828071_ChIP-Seq_BEAS2B_Human1.24826059
61* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.24523512
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.24194383
63LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.22291221
64GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.21976273
65RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.21680913
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20992964
67PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.20883077
68NR3C1_23031785_ChIP-Seq_PC12_Mouse1.20483903
69TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.19803695
70SOX2_21211035_ChIP-Seq_LN229_Gbm1.17785165
71AR_19668381_ChIP-Seq_PC3_Human1.17610114
72ZNF274_21170338_ChIP-Seq_K562_Hela1.16597569
73CTBP2_25329375_ChIP-Seq_LNCAP_Human1.15186343
74VDR_24763502_ChIP-Seq_THP-1_Human1.13264679
75VDR_21846776_ChIP-Seq_THP-1_Human1.12317572
76NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.11816169
77CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11648774
78EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.11214335
79SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10838383
80NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.10771822
81* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.10592120
82BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.10002860
83SMAD4_21799915_ChIP-Seq_A2780_Human1.09654505
84P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08491632
85SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08272028
86RUNX_20019798_ChIP-Seq_JUKART_Human1.08129460
87ARNT_22903824_ChIP-Seq_MCF-7_Human1.07708852
88KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07634733
89AHR_22903824_ChIP-Seq_MCF-7_Human1.05781207
90ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04494585
91* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04377100
92MYB_21317192_ChIP-Seq_ERMYB_Mouse1.03333222
93* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.03058554
94IRF8_22096565_ChIP-ChIP_GC-B_Human1.02463000
95Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.01456762
96YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98757769
97FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.98705914
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98347535
99ESR2_21235772_ChIP-Seq_MCF-7_Human0.98098088
100NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95851154
101CTCF_27219007_Chip-Seq_Bcells_Human0.95739156
102PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95460819
103SMAD3_21741376_ChIP-Seq_EPCs_Human0.95026385
104MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.94484080
105RUNX1_22412390_ChIP-Seq_EML_Mouse0.94348753
106AR_25329375_ChIP-Seq_VCAP_Human0.94270618
107DPY_21335234_ChIP-Seq_ESCs_Mouse0.93488880
108OCT4_19829295_ChIP-Seq_ESCs_Human0.92085980
109RXR_22108803_ChIP-Seq_LS180_Human0.91692023
110SMAD3_21741376_ChIP-Seq_ESCs_Human0.91691590
111GATA1_19941827_ChIP-Seq_MEL86_Mouse0.91494957
112* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.89848855
113OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.89774722
114GATA1_19941826_ChIP-Seq_K562_Human0.89205362
115SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.89007469
116VDR_24787735_ChIP-Seq_THP-1_Human0.88655745
117PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.88086868
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.87944026
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87605795
120POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87605795
121KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.87583633
122* LXR_22292898_ChIP-Seq_THP-1_Human0.87558306
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87447984
124ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.87111089
125STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.86880184
126STAT3_23295773_ChIP-Seq_U87_Human0.86822750
127P300_19829295_ChIP-Seq_ESCs_Human0.86340062
128SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86325347
129TP53_16413492_ChIP-PET_HCT116_Human0.86130740
130SMAD3_21741376_ChIP-Seq_HESCs_Human0.86011968
131* TCF7_22412390_ChIP-Seq_EML_Mouse0.85715876
132MYC_22102868_ChIP-Seq_BL_Human0.85545488
133SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.85168946
134TAF15_26573619_Chip-Seq_HEK293_Human0.84802753
135GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.84490053
136ELK4_26923725_Chip-Seq_MESODERM_Mouse0.84236167
137STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.84186710
138TET1_21490601_ChIP-Seq_MESCs_Mouse0.83901144
139SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83792575
140NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.83765777
141PRDM14_20953172_ChIP-Seq_ESCs_Human0.83277400
142* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.81902574
143PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81261847
144* KLF4_19829295_ChIP-Seq_ESCs_Human0.81103515
145SMC4_20622854_ChIP-Seq_HELA_Human0.79975402

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.03788627
2MP0003880_abnormal_central_pattern4.51354811
3MP0003635_abnormal_synaptic_transmissio4.17577271
4MP0004270_analgesia3.49102054
5MP0002063_abnormal_learning/memory/cond3.37840961
6MP0009745_abnormal_behavioral_response3.24979719
7MP0003724_increased_susceptibility_to3.12771127
8MP0002064_seizures2.95822582
9MP0002822_catalepsy2.79051873
10MP0005423_abnormal_somatic_nervous2.77188724
11MP0001968_abnormal_touch/_nociception2.65521450
12MP0002572_abnormal_emotion/affect_behav2.54931107
13MP0009046_muscle_twitch2.40912219
14MP0001486_abnormal_startle_reflex2.31020449
15MP0000778_abnormal_nervous_system2.26302108
16MP0005464_abnormal_platelet_physiology2.20925916
17MP0003436_decreased_susceptibility_to2.20429149
18MP0002734_abnormal_mechanical_nocicepti2.17983958
19MP0002909_abnormal_adrenal_gland2.10929944
20MP0002272_abnormal_nervous_system2.06946366
21MP0004858_abnormal_nervous_system2.03147069
22MP0004811_abnormal_neuron_physiology2.00666464
23MP0009780_abnormal_chondrocyte_physiolo1.99862723
24MP0008569_lethality_at_weaning1.98354314
25MP0002736_abnormal_nociception_after1.90931131
26MP0002733_abnormal_thermal_nociception1.88393094
27MP0000569_abnormal_digit_pigmentation1.87521921
28MP0001440_abnormal_grooming_behavior1.83146522
29MP0008004_abnormal_stomach_pH1.79893860
30MP0001501_abnormal_sleep_pattern1.75127965
31MP0002067_abnormal_sensory_capabilities1.74710477
32MP0003329_amyloid_beta_deposits1.73759738
33MP0002184_abnormal_innervation1.73419838
34MP0002735_abnormal_chemical_nociception1.71099042
35MP0004885_abnormal_endolymph1.70982898
36MP0002653_abnormal_ependyma_morphology1.70925674
37MP0003787_abnormal_imprinting1.69956085
38MP0001970_abnormal_pain_threshold1.68800932
39MP0002557_abnormal_social/conspecific_i1.66493924
40MP0000955_abnormal_spinal_cord1.63761083
41MP0008961_abnormal_basal_metabolism1.59940856
42MP0005000_abnormal_immune_tolerance1.58640400
43MP0010234_abnormal_vibrissa_follicle1.51958616
44MP0002419_abnormal_innate_immunity1.51593000
45MP0005386_behavior/neurological_phenoty1.51006421
46MP0004924_abnormal_behavior1.51006421
47MP0005671_abnormal_response_to1.49792362
48MP0006082_CNS_inflammation1.49634775
49MP0003879_abnormal_hair_cell1.47915996
50MP0001790_abnormal_immune_system1.47793849
51MP0005387_immune_system_phenotype1.47793849
52MP0001835_abnormal_antigen_presentation1.46097584
53MP0003303_peritoneal_inflammation1.43643281
54MP0002148_abnormal_hypersensitivity_rea1.40059188
55MP0004510_myositis1.36954079
56MP0002882_abnormal_neuron_morphology1.36093298
57MP0002066_abnormal_motor_capabilities/c1.35875815
58MP0005025_abnormal_response_to1.33892535
59MP0005058_abnormal_lysosome_morphology1.30031036
60MP0001800_abnormal_humoral_immune1.29706814
61MP0003633_abnormal_nervous_system1.28976554
62MP0002152_abnormal_brain_morphology1.26418298
63MP0002723_abnormal_immune_serum1.25492457
64MP0009764_decreased_sensitivity_to1.20067622
65MP0005623_abnormal_meninges_morphology1.18917256
66MP0009278_abnormal_bone_marrow1.18272218
67MP0002452_abnormal_antigen_presenting1.16770256
68MP0001984_abnormal_olfaction1.16547717
69MP0001533_abnormal_skeleton_physiology1.16081456
70MP0009785_altered_susceptibility_to1.14301768
71MP0002420_abnormal_adaptive_immunity1.12918138
72MP0003123_paternal_imprinting1.12823309
73MP0003183_abnormal_peptide_metabolism1.12446209
74MP0001819_abnormal_immune_cell1.11258478
75MP0005645_abnormal_hypothalamus_physiol1.10337867
76MP0000343_altered_response_to1.10104583
77MP0001348_abnormal_lacrimal_gland1.08297896
78MP0008874_decreased_physiological_sensi1.07880593
79MP0003631_nervous_system_phenotype1.04269899
80MP0006276_abnormal_autonomic_nervous1.03041459
81MP0003075_altered_response_to0.98331831
82MP0000013_abnormal_adipose_tissue0.97490231
83MP0003828_pulmonary_edema0.94823833
84MP0003122_maternal_imprinting0.92698829
85MP0005646_abnormal_pituitary_gland0.92206823
86MP0000465_gastrointestinal_hemorrhage0.91294828
87MP0004947_skin_inflammation0.90215397
88MP0001502_abnormal_circadian_rhythm0.89318356
89MP0002069_abnormal_eating/drinking_beha0.87730070
90MP0000685_abnormal_immune_system0.86717825
91MP0001177_atelectasis0.86687775
92MP0003634_abnormal_glial_cell0.86130960
93MP0000751_myopathy0.86083761
94MP0003690_abnormal_glial_cell0.85880204
95MP0001905_abnormal_dopamine_level0.85257141
96MP0008260_abnormal_autophagy0.84978549
97MP0005394_taste/olfaction_phenotype0.84570759
98MP0005499_abnormal_olfactory_system0.84570759
99MP0004233_abnormal_muscle_weight0.84098775
100MP0003861_abnormal_nervous_system0.83646455
101MP0000604_amyloidosis0.83542973
102MP0001529_abnormal_vocalization0.83451003
103MP0002998_abnormal_bone_remodeling0.81490888
104MP0005167_abnormal_blood-brain_barrier0.77385022
105MP0003283_abnormal_digestive_organ0.76027392
106MP0002332_abnormal_exercise_endurance0.74589093
107MP0004085_abnormal_heartbeat0.72621919
108MP0000716_abnormal_immune_system0.72525540
109MP0004142_abnormal_muscle_tone0.71969553
110MP0004130_abnormal_muscle_cell0.70778390
111MP0000920_abnormal_myelination0.70474672
112MP0005187_abnormal_penis_morphology0.69722137
113MP0010155_abnormal_intestine_physiology0.69195862
114MP0002398_abnormal_bone_marrow0.69072825
115MP0005310_abnormal_salivary_gland0.67940574
116MP0000631_abnormal_neuroendocrine_gland0.67619720
117MP0001845_abnormal_inflammatory_respons0.66994881
118MP0002234_abnormal_pharynx_morphology0.65699153
119MP0008872_abnormal_physiological_respon0.65650834
120MP0001943_abnormal_respiration0.64808377
121MP0004484_altered_response_of0.63802737
122MP0003091_abnormal_cell_migration0.63406593
123MP0004742_abnormal_vestibular_system0.63255428
124MP0005409_darkened_coat_color0.62543676
125MP0003632_abnormal_nervous_system0.62537673
126MP0003172_abnormal_lysosome_physiology0.61307621
127MP0005535_abnormal_body_temperature0.59377220
128MP0002229_neurodegeneration0.57965473
129MP0002090_abnormal_vision0.57488500
130MP0010769_abnormal_survival0.57280190
131MP0001963_abnormal_hearing_physiology0.55578420
132MP0003137_abnormal_impulse_conducting0.55537398
133MP0002752_abnormal_somatic_nervous0.54930167
134MP0003045_fibrosis0.54918000
135MP0002082_postnatal_lethality0.53176698
136MP0010770_preweaning_lethality0.53176698
137MP0010768_mortality/aging0.52669914
138MP0005166_decreased_susceptibility_to0.51444463
139MP0003300_gastrointestinal_ulcer0.51335523

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.85778417
2Focal motor seizures (HP:0011153)5.34751214
3Focal seizures (HP:0007359)4.56049909
4Visual hallucinations (HP:0002367)4.17890206
5Prolonged bleeding time (HP:0003010)3.93308451
6Supranuclear gaze palsy (HP:0000605)3.81013164
7Eczematoid dermatitis (HP:0000976)3.75990038
8Purpura (HP:0000979)3.71935160
9Abnormality of macrophages (HP:0004311)3.56323910
10Mutism (HP:0002300)3.53874978
11Recurrent bacterial skin infections (HP:0005406)3.50156823
12Papilledema (HP:0001085)3.47392396
13Retrobulbar optic neuritis (HP:0100654)3.44040836
14Optic neuritis (HP:0100653)3.44040836
15Action tremor (HP:0002345)3.38444601
16Orchitis (HP:0100796)3.28150033
17Epileptic encephalopathy (HP:0200134)3.28127580
18Ankle clonus (HP:0011448)3.27701777
19Recurrent abscess formation (HP:0002722)3.15082512
20Petechiae (HP:0000967)3.12955388
21Stomatitis (HP:0010280)3.08863497
22Atonic seizures (HP:0010819)3.07249615
23Poor eye contact (HP:0000817)3.05709710
24Impaired vibration sensation in the lower limbs (HP:0002166)3.04525640
25Urinary urgency (HP:0000012)3.00919344
26Agammaglobulinemia (HP:0004432)2.99833294
27Absence seizures (HP:0002121)2.99697513
28Progressive cerebellar ataxia (HP:0002073)2.97238658
29Myositis (HP:0100614)2.97175234
30Megalencephaly (HP:0001355)2.92601466
31Abnormal platelet volume (HP:0011876)2.90051972
32Urinary bladder sphincter dysfunction (HP:0002839)2.89567480
33Broad-based gait (HP:0002136)2.86683538
34Depression (HP:0000716)2.86672765
35Abnormal social behavior (HP:0012433)2.84226999
36Impaired social interactions (HP:0000735)2.84226999
37Febrile seizures (HP:0002373)2.80888512
38Spontaneous hematomas (HP:0007420)2.79068035
39Truncal ataxia (HP:0002078)2.77182392
40Peripheral hypomyelination (HP:0007182)2.76719106
41Pointed chin (HP:0000307)2.74188167
42Amblyopia (HP:0000646)2.71874903
43Postural instability (HP:0002172)2.68255108
44Dialeptic seizures (HP:0011146)2.68056007
45Insidious onset (HP:0003587)2.64739899
46Termporal pattern (HP:0011008)2.64739899
47Recurrent gram-negative bacterial infections (HP:0005420)2.63893783
48Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.62164810
49Disinhibition (HP:0000734)2.61893281
50Stereotypic behavior (HP:0000733)2.61160159
51Epistaxis (HP:0000421)2.59947697
52Generalized tonic-clonic seizures (HP:0002069)2.59841876
53Increased mean platelet volume (HP:0011877)2.59822597
54Menorrhagia (HP:0000132)2.59528289
55Abnormal eating behavior (HP:0100738)2.57357255
56Mediastinal lymphadenopathy (HP:0100721)2.55456068
57Ankyloglossia (HP:0010296)2.52493517
58Drooling (HP:0002307)2.51685159
59Excessive salivation (HP:0003781)2.51685159
60Gingival bleeding (HP:0000225)2.51405328
61Insomnia (HP:0100785)2.49298999
62Chronic obstructive pulmonary disease (HP:0006510)2.48832353
63Obstructive lung disease (HP:0006536)2.48832353
64Apathy (HP:0000741)2.47832636
65Inappropriate behavior (HP:0000719)2.43358902
66Cerebral inclusion bodies (HP:0100314)2.41971063
67Hyperacusis (HP:0010780)2.41054502
68Increased cerebral lipofuscin (HP:0011813)2.40412073
69Keratoconjunctivitis sicca (HP:0001097)2.39890904
70Progressive inability to walk (HP:0002505)2.37434119
71Verrucae (HP:0200043)2.36696033
72Papilloma (HP:0012740)2.36696033
73Abnormality of the lower motor neuron (HP:0002366)2.35495488
74Dysmetria (HP:0001310)2.32699281
75Torticollis (HP:0000473)2.32526187
76Spastic gait (HP:0002064)2.31415351
77Annular pancreas (HP:0001734)2.28786047
78Anxiety (HP:0000739)2.28700072
79Memory impairment (HP:0002354)2.27941538
80Abnormality of binocular vision (HP:0011514)2.26541445
81Diplopia (HP:0000651)2.26541445
82Diminished motivation (HP:0000745)2.26345984
83Amyotrophic lateral sclerosis (HP:0007354)2.25935540
84Genetic anticipation (HP:0003743)2.25153210
85Hemiplegia (HP:0002301)2.25047187
86Dysdiadochokinesis (HP:0002075)2.24537859
87Impaired smooth pursuit (HP:0007772)2.22295248
88Vertebral arch anomaly (HP:0008438)2.21962906
89Episodic fever (HP:0001954)2.21543085
90Hemiparesis (HP:0001269)2.19497906
91Resting tremor (HP:0002322)2.16731352
92Neurofibrillary tangles (HP:0002185)2.15012938
93Meningitis (HP:0001287)2.14726648
94Keratoconjunctivitis (HP:0001096)2.14399028
95Vertigo (HP:0002321)2.13228786
96Aqueductal stenosis (HP:0002410)2.10853687
97Intention tremor (HP:0002080)2.08763129
98Hyperventilation (HP:0002883)2.07923359
99Lower limb asymmetry (HP:0100559)2.07328619
100Focal dystonia (HP:0004373)2.06658622
101Macroorchidism (HP:0000053)2.05897645
102Encephalitis (HP:0002383)2.05600285
103Gaze-evoked nystagmus (HP:0000640)2.05331924
104Lower limb muscle weakness (HP:0007340)2.05271898
105Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.05219670
106Abnormality of the corticospinal tract (HP:0002492)2.04463077
107Amyloidosis (HP:0011034)2.03534638
108Increased IgM level (HP:0003496)2.02357960
109Elfin facies (HP:0004428)2.00815161
110Anomalous pulmonary venous return (HP:0010772)2.00617812
111Bradykinesia (HP:0002067)2.00505070
112Dysmetric saccades (HP:0000641)1.98191020
113Lower limb amyotrophy (HP:0007210)1.97690754
114Vasculitis (HP:0002633)1.96694565
115Neuronal loss in central nervous system (HP:0002529)1.96629249
116Rapidly progressive (HP:0003678)1.94754814
117Sleep apnea (HP:0010535)1.94299048
118Abnormality of ocular smooth pursuit (HP:0000617)1.92204450
119Elevated erythrocyte sedimentation rate (HP:0003565)1.91205585
120Cellulitis (HP:0100658)1.90958479
121Abnormality of glycolipid metabolism (HP:0010969)1.90770310
122Abnormality of liposaccharide metabolism (HP:0010968)1.90770310
123Abnormality of glycosphingolipid metabolism (HP:0004343)1.90770310
124Abnormality of oral frenula (HP:0000190)1.89572950
125Ventricular fibrillation (HP:0001663)1.88996565
126Dysostosis multiplex (HP:0000943)1.88988605
127Obstructive sleep apnea (HP:0002870)1.88609482
128Dementia (HP:0000726)1.87202536
129Craniofacial dystonia (HP:0012179)1.84655461
130Colitis (HP:0002583)1.84615851
131Polyphagia (HP:0002591)1.84558145
132Generalized hypotonia (HP:0001290)1.82728315
133Loss of speech (HP:0002371)1.80469457
134Scanning speech (HP:0002168)1.80236830
135Abnormality of salivation (HP:0100755)1.79754923
136Recurrent skin infections (HP:0001581)1.79467482
137Neoplasm of the heart (HP:0100544)1.77125560
138Urticaria (HP:0001025)1.76119518
139Rigidity (HP:0002063)1.75116643
140Muscle fiber splitting (HP:0003555)1.74904540
141Impaired vibratory sensation (HP:0002495)1.73638414
142Obsessive-compulsive behavior (HP:0000722)1.71444944
143Bowel incontinence (HP:0002607)1.71163252
144Limb dystonia (HP:0002451)1.69058423
145Arterial tortuosity (HP:0005116)1.68011993
146Buphthalmos (HP:0000557)1.67117574
147Agitation (HP:0000713)1.66231191
148Epileptiform EEG discharges (HP:0011182)1.65722203
149Sporadic (HP:0003745)1.63732079
150EEG with generalized epileptiform discharges (HP:0011198)1.63666958

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K94.27609867
2EPHA43.95007607
3MARK13.74715956
4NTRK33.43295980
5RIPK42.73841681
6SIK22.59499264
7MINK12.45669068
8KSR22.34820069
9MAP3K42.31875014
10DAPK22.20107998
11PAK62.19669493
12NTRK22.03720316
13KSR12.01269008
14CASK1.99341254
15CAMKK11.94834748
16PRKD31.94694900
17MAP3K111.83373731
18MAP3K131.77144120
19BLK1.74211505
20MAP3K101.66632720
21NTRK11.56753499
22CDK51.48631192
23CSK1.48442597
24TRIB31.47337495
25TYRO31.47228856
26MAP2K71.46955450
27MAPK131.41410805
28IRAK41.39159421
29FES1.37428965
30BMPR21.33146943
31MAP2K41.26246451
32IRAK21.26038829
33MATK1.21951101
34RET1.20104150
35MAP4K11.18489861
36UHMK11.14306614
37DAPK11.13126394
38MAP3K21.12652646
39TAOK11.10581916
40GRK61.09963843
41TAOK21.09507081
42STK111.08489409
43CAMK1G1.07288922
44ALK1.06865392
45DYRK1B1.06037863
46PKN11.04008610
47MAP2K31.02244647
48PLK21.00317041
49PHKG20.98404775
50PHKG10.98404775
51PNCK0.98357790
52SIK30.98015503
53MARK20.95672101
54FGFR20.94966183
55EEF2K0.94364227
56JAK20.93817231
57BTK0.93163280
58MAP3K10.89273407
59MAP3K120.88323563
60LATS20.87414631
61STK380.86791387
62ZAP700.86640416
63BMX0.86483074
64CDK190.84335354
65DYRK20.84197368
66PRKCH0.84184336
67DMPK0.83226535
68CDK140.81983951
69CDK150.81821539
70PAK30.81816818
71CDK180.81138779
72RAF10.78357808
73ARAF0.77609851
74GRK50.77030994
75SCYL20.76482097
76RIPK10.76412185
77DDR20.74477441
78TYK20.73536322
79PDK10.72440251
80LMTK20.71735154
81PRKCG0.71516238
82CDK11A0.71434998
83PKN20.70789018
84DYRK1A0.67959786
85CSNK1G20.66525885
86LYN0.65795802
87SYK0.65356648
88WNK10.64654750
89EPHB10.64177898
90MAP3K70.64161142
91PTK2B0.64158969
92CAMK10.64064569
93PRPF4B0.63309583
94PRKCZ0.63126981
95CAMKK20.63019427
96SGK30.62292827
97FYN0.61577614
98SGK10.60063874
99SGK4940.58805163
100SGK2230.58805163
101MAP2K10.58633054
102PDPK10.58043146
103JAK10.58007596
104IKBKE0.56751252
105FGR0.54990262
106MOS0.54656313
107CDC42BPA0.54489096
108MAPK120.54447522
109IRAK30.52905489
110MAPK40.52862136
111PDGFRA0.52463491
112EPHA30.50434647
113MAP3K140.50022400
114TBK10.49901022
115TNIK0.49016533
116EPHB20.48340984
117YES10.47702746
118ICK0.47440341
119MAP3K30.46406535
120LCK0.45326203
121MAP3K50.45129477
122CAMK2A0.45054307
123PRKD10.44472330
124ERBB30.44460948
125LRRK20.42539515
126PRKD20.41961495
127MAPK100.41413255
128ROCK20.40600170
129RPS6KA30.40141824
130TNK20.39506804
131HCK0.38188441
132SGK20.37476995
133FGFR30.35855650
134CAMK40.35463446
135RPS6KA20.35181081
136CSF1R0.33930924
137HIPK20.31994864

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047402.50178323
2Nicotine addiction_Homo sapiens_hsa050332.45964017
3Long-term potentiation_Homo sapiens_hsa047202.36529584
4Synaptic vesicle cycle_Homo sapiens_hsa047212.28183163
5Circadian entrainment_Homo sapiens_hsa047132.25058877
6Glutamatergic synapse_Homo sapiens_hsa047242.14711144
7Morphine addiction_Homo sapiens_hsa050322.08478352
8GABAergic synapse_Homo sapiens_hsa047272.04195691
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.03036930
10Amphetamine addiction_Homo sapiens_hsa050312.01527721
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.99172654
12Dopaminergic synapse_Homo sapiens_hsa047281.93607912
13Salivary secretion_Homo sapiens_hsa049701.81158522
14Gastric acid secretion_Homo sapiens_hsa049711.78770241
15Cholinergic synapse_Homo sapiens_hsa047251.78583948
16Aldosterone synthesis and secretion_Homo sapiens_hsa049251.67084589
17Oxytocin signaling pathway_Homo sapiens_hsa049211.61730080
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60546447
19Renin secretion_Homo sapiens_hsa049241.59534624
20Toll-like receptor signaling pathway_Homo sapiens_hsa046201.58438759
21Glioma_Homo sapiens_hsa052141.56798906
22Leishmaniasis_Homo sapiens_hsa051401.53472080
23B cell receptor signaling pathway_Homo sapiens_hsa046621.49944226
24GnRH signaling pathway_Homo sapiens_hsa049121.47408835
25Insulin secretion_Homo sapiens_hsa049111.47190387
26Cocaine addiction_Homo sapiens_hsa050301.43570800
27Long-term depression_Homo sapiens_hsa047301.43060024
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41859547
29Gap junction_Homo sapiens_hsa045401.37202847
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.36131956
31Tuberculosis_Homo sapiens_hsa051521.34806440
32Estrogen signaling pathway_Homo sapiens_hsa049151.29316292
33Calcium signaling pathway_Homo sapiens_hsa040201.27065314
34Axon guidance_Homo sapiens_hsa043601.26890871
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25848247
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.24851663
37ErbB signaling pathway_Homo sapiens_hsa040121.20400623
38Staphylococcus aureus infection_Homo sapiens_hsa051501.19713855
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.17736184
40Taste transduction_Homo sapiens_hsa047421.17667877
41Type II diabetes mellitus_Homo sapiens_hsa049301.17340962
42Serotonergic synapse_Homo sapiens_hsa047261.15341715
43cAMP signaling pathway_Homo sapiens_hsa040241.12096219
44VEGF signaling pathway_Homo sapiens_hsa043701.10754927
45Malaria_Homo sapiens_hsa051441.09685189
46Non-small cell lung cancer_Homo sapiens_hsa052231.09599963
47Phospholipase D signaling pathway_Homo sapiens_hsa040721.09153966
48Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.07949152
49Salmonella infection_Homo sapiens_hsa051321.07299713
50Phagosome_Homo sapiens_hsa041451.06362782
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04004452
52NOD-like receptor signaling pathway_Homo sapiens_hsa046211.02551967
53Notch signaling pathway_Homo sapiens_hsa043301.01405785
54Melanogenesis_Homo sapiens_hsa049161.00904791
55Dorso-ventral axis formation_Homo sapiens_hsa043201.00830906
56Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.99708338
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.96460176
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93721622
59Rheumatoid arthritis_Homo sapiens_hsa053230.93475509
60Endometrial cancer_Homo sapiens_hsa052130.93031112
61Choline metabolism in cancer_Homo sapiens_hsa052310.92021287
62MAPK signaling pathway_Homo sapiens_hsa040100.91868498
63mTOR signaling pathway_Homo sapiens_hsa041500.91755212
64Allograft rejection_Homo sapiens_hsa053300.89709393
65Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89589606
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.89312124
67Chemokine signaling pathway_Homo sapiens_hsa040620.85069217
68Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.85037507
69Renal cell carcinoma_Homo sapiens_hsa052110.83789687
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83614596
71Oocyte meiosis_Homo sapiens_hsa041140.83509441
72Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83116027
73Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.83057912
74Prion diseases_Homo sapiens_hsa050200.82155222
75Nitrogen metabolism_Homo sapiens_hsa009100.82137327
76TNF signaling pathway_Homo sapiens_hsa046680.81990370
77Colorectal cancer_Homo sapiens_hsa052100.81324346
78Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80736750
79Graft-versus-host disease_Homo sapiens_hsa053320.80166265
80Toxoplasmosis_Homo sapiens_hsa051450.76137682
81Rap1 signaling pathway_Homo sapiens_hsa040150.76134567
82Endocytosis_Homo sapiens_hsa041440.74074013
83Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73921418
84Chronic myeloid leukemia_Homo sapiens_hsa052200.73890651
85Pertussis_Homo sapiens_hsa051330.73495247
86Acute myeloid leukemia_Homo sapiens_hsa052210.73013863
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.72926351
88Vascular smooth muscle contraction_Homo sapiens_hsa042700.72273527
89Leukocyte transendothelial migration_Homo sapiens_hsa046700.70197981
90NF-kappa B signaling pathway_Homo sapiens_hsa040640.69600809
91Dilated cardiomyopathy_Homo sapiens_hsa054140.69377272
92Alcoholism_Homo sapiens_hsa050340.69215317
93Autoimmune thyroid disease_Homo sapiens_hsa053200.69012338
94Shigellosis_Homo sapiens_hsa051310.67268138
95Hematopoietic cell lineage_Homo sapiens_hsa046400.66853336
96Thyroid hormone synthesis_Homo sapiens_hsa049180.66822796
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66490508
98Pancreatic cancer_Homo sapiens_hsa052120.66466036
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66325642
100Ras signaling pathway_Homo sapiens_hsa040140.65352047
101Type I diabetes mellitus_Homo sapiens_hsa049400.65299085
102Platelet activation_Homo sapiens_hsa046110.64733018
103Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.64372598
104Influenza A_Homo sapiens_hsa051640.64197661
105Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.63438841
106T cell receptor signaling pathway_Homo sapiens_hsa046600.63308837
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61861414
108Lysosome_Homo sapiens_hsa041420.61591975
109Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.61574297
110Pancreatic secretion_Homo sapiens_hsa049720.61568254
111Inositol phosphate metabolism_Homo sapiens_hsa005620.60454683
112Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60412455
113Legionellosis_Homo sapiens_hsa051340.60375364
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.60316682
115Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59766943
116Osteoclast differentiation_Homo sapiens_hsa043800.59125013
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.59110319
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.58475774
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.58445659
120Insulin signaling pathway_Homo sapiens_hsa049100.55771344
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54260613
122Glucagon signaling pathway_Homo sapiens_hsa049220.54219921
123Collecting duct acid secretion_Homo sapiens_hsa049660.54088387
124Wnt signaling pathway_Homo sapiens_hsa043100.53938371
125Prolactin signaling pathway_Homo sapiens_hsa049170.51949553
126African trypanosomiasis_Homo sapiens_hsa051430.50183927
127Proteoglycans in cancer_Homo sapiens_hsa052050.47822191
128Regulation of actin cytoskeleton_Homo sapiens_hsa048100.47655918
129Cardiac muscle contraction_Homo sapiens_hsa042600.47130330
130Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.46922941
131Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46080385

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