SNRNP48

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)6.75051408
2maturation of SSU-rRNA (GO:0030490)6.08567530
3nuclear pore complex assembly (GO:0051292)6.03659104
4viral transcription (GO:0019083)5.80669686
5ribosomal small subunit assembly (GO:0000028)5.75292793
6translational termination (GO:0006415)5.65666877
7nuclear pore organization (GO:0006999)5.45596447
8regulation of centriole replication (GO:0046599)5.09526708
9cotranslational protein targeting to membrane (GO:0006613)5.02444550
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.96807045
11protein targeting to ER (GO:0045047)4.92588630
12mitotic sister chromatid segregation (GO:0000070)4.78757980
13sister chromatid segregation (GO:0000819)4.74730579
14establishment of protein localization to endoplasmic reticulum (GO:0072599)4.72875941
15ribosomal large subunit biogenesis (GO:0042273)4.61739988
16protein localization to endoplasmic reticulum (GO:0070972)4.61081631
17translational elongation (GO:0006414)4.55069659
18mitotic sister chromatid cohesion (GO:0007064)4.45841693
19kinetochore organization (GO:0051383)4.45561278
20cellular protein complex disassembly (GO:0043624)4.38463007
21mitotic chromosome condensation (GO:0007076)4.38398228
22nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.37233550
23DNA unwinding involved in DNA replication (GO:0006268)4.36144081
24viral life cycle (GO:0019058)4.25045959
25pore complex assembly (GO:0046931)4.24357671
26protein localization to chromosome, centromeric region (GO:0071459)4.24029141
27kinetochore assembly (GO:0051382)4.22648486
28regulation of centrosome cycle (GO:0046605)4.22491815
29translational initiation (GO:0006413)4.22013579
30protein localization to kinetochore (GO:0034501)4.18949421
31regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.04392090
32regulation of centrosome duplication (GO:0010824)3.90127873
33proteasome assembly (GO:0043248)3.77736817
34mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.75314486
35regulation of mitotic spindle checkpoint (GO:1903504)3.74029843
36regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.74029843
37rRNA processing (GO:0006364)3.71807263
38ribonucleoprotein complex biogenesis (GO:0022613)3.69090320
39protein complex disassembly (GO:0043241)3.67623651
40mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.65685493
41rRNA metabolic process (GO:0016072)3.53978275
42telomere maintenance via semi-conservative replication (GO:0032201)3.52620144
43replication fork processing (GO:0031297)3.52492818
44mitotic metaphase plate congression (GO:0007080)3.48808326
45DNA topological change (GO:0006265)3.48571942
46nuclear-transcribed mRNA catabolic process (GO:0000956)3.47855864
47macromolecular complex disassembly (GO:0032984)3.46737828
48translation (GO:0006412)3.45839948
49regulation of DNA endoreduplication (GO:0032875)3.44121159
50ATP synthesis coupled proton transport (GO:0015986)3.35335892
51energy coupled proton transport, down electrochemical gradient (GO:0015985)3.35335892
52mesenchymal cell differentiation involved in kidney development (GO:0072161)3.35286065
53mesenchymal cell differentiation involved in renal system development (GO:2001012)3.35286065
54mRNA catabolic process (GO:0006402)3.35132753
55CENP-A containing nucleosome assembly (GO:0034080)3.33018448
56mitotic nuclear envelope disassembly (GO:0007077)3.32660996
57telomere maintenance via recombination (GO:0000722)3.30446070
58mitotic G2/M transition checkpoint (GO:0044818)3.27904386
59regulation of chromosome segregation (GO:0051983)3.21209172
60establishment of integrated proviral latency (GO:0075713)3.20232495
61spindle checkpoint (GO:0031577)3.19701031
62regulation of spindle checkpoint (GO:0090231)3.19574743
63formation of translation preinitiation complex (GO:0001731)3.18214353
64central nervous system myelination (GO:0022010)3.17830896
65axon ensheathment in central nervous system (GO:0032291)3.17830896
66chromosome segregation (GO:0007059)3.16171661
67negative regulation of chromosome segregation (GO:0051985)3.15500148
68mitotic recombination (GO:0006312)3.15200516
69RNA catabolic process (GO:0006401)3.14109092
70chromatin remodeling at centromere (GO:0031055)3.14059672
71regulation of RNA export from nucleus (GO:0046831)3.13522501
72histone exchange (GO:0043486)3.13300748
73protein targeting to membrane (GO:0006612)3.12292329
74mature B cell differentiation involved in immune response (GO:0002313)3.12036321
75negative regulation of epidermal cell differentiation (GO:0045605)3.11494402
76positive regulation of histone H3-K4 methylation (GO:0051571)3.11251341
77DNA strand elongation involved in DNA replication (GO:0006271)3.09937304
78nuclear envelope disassembly (GO:0051081)3.09297001
79membrane disassembly (GO:0030397)3.09297001
80negative regulation of mitotic sister chromatid separation (GO:2000816)3.09263763
81negative regulation of sister chromatid segregation (GO:0033046)3.09263763
82negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.09263763
83negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.09263763
84negative regulation of mitotic sister chromatid segregation (GO:0033048)3.09263763
85DNA replication initiation (GO:0006270)3.08283118
86sister chromatid cohesion (GO:0007062)3.07866147
87mitotic spindle checkpoint (GO:0071174)3.05840684
88DNA synthesis involved in DNA repair (GO:0000731)3.05305898
89protein neddylation (GO:0045116)3.05204377
90transcription-coupled nucleotide-excision repair (GO:0006283)3.05107739
91regulation of mitotic spindle organization (GO:0060236)3.04511438
92regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.04449727
93cellular component biogenesis (GO:0044085)3.03916863
94regulation of mitotic metaphase/anaphase transition (GO:0030071)3.03494505
95regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.03494505
96regulation of sister chromatid segregation (GO:0033045)2.99692962
97regulation of mitotic sister chromatid separation (GO:0010965)2.99692962
98regulation of mitotic sister chromatid segregation (GO:0033047)2.99692962
99heterochromatin organization (GO:0070828)2.97221316
100mitotic spindle assembly checkpoint (GO:0007094)2.96237555
101DNA strand elongation (GO:0022616)2.96150927
102regulation of DNA damage checkpoint (GO:2000001)2.95913469
103DNA duplex unwinding (GO:0032508)2.95815189
104transcription elongation from RNA polymerase I promoter (GO:0006362)2.95447288
105positive regulation of chromosome segregation (GO:0051984)2.95332679
106spindle assembly checkpoint (GO:0071173)2.94529025
107telomere maintenance via telomerase (GO:0007004)2.94387552
108metaphase plate congression (GO:0051310)2.93686137
109nucleotide-excision repair, DNA gap filling (GO:0006297)2.92879080
110DNA deamination (GO:0045006)2.92789161
111DNA replication checkpoint (GO:0000076)2.92775652
112DNA ligation (GO:0006266)2.92581119
113DNA geometric change (GO:0032392)2.92043757
114positive regulation of mitotic sister chromatid separation (GO:1901970)2.91270902
115positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.91270902
116positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.91270902
117regulation of translational fidelity (GO:0006450)2.91136641
118purine nucleobase biosynthetic process (GO:0009113)2.90962379
119termination of RNA polymerase I transcription (GO:0006363)2.90680376
120centriole replication (GO:0007099)2.90320089
121exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.89636046
122meiotic chromosome segregation (GO:0045132)2.89383416
123nucleobase biosynthetic process (GO:0046112)2.87969936
124centrosome organization (GO:0051297)2.87237746
125establishment of chromosome localization (GO:0051303)2.86451703
126regulation of sister chromatid cohesion (GO:0007063)2.86425908
127termination of RNA polymerase III transcription (GO:0006386)2.86085318
128transcription elongation from RNA polymerase III promoter (GO:0006385)2.86085318
129attachment of spindle microtubules to kinetochore (GO:0008608)2.85864908
130RNA capping (GO:0036260)2.85277403
1317-methylguanosine RNA capping (GO:0009452)2.85277403
132inner cell mass cell proliferation (GO:0001833)2.84641355
133regulation of spindle organization (GO:0090224)2.84566355
134negative regulation of transcription by competitive promoter binding (GO:0010944)2.84300822
135radial glial cell differentiation (GO:0060019)2.84264528
136IMP biosynthetic process (GO:0006188)2.83653746
137chromosome condensation (GO:0030261)2.83237477
138nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.83158651
139protein localization to chromosome (GO:0034502)2.82052987
140folic acid-containing compound biosynthetic process (GO:0009396)2.80884505
141ncRNA 3-end processing (GO:0043628)2.80770381
1427-methylguanosine mRNA capping (GO:0006370)2.80690095
143respiratory electron transport chain (GO:0022904)2.78133532
144establishment of viral latency (GO:0019043)2.74991309
145mature B cell differentiation (GO:0002335)2.74404584
146ncRNA processing (GO:0034470)2.73382559
147electron transport chain (GO:0022900)2.72771685
148establishment of protein localization to mitochondrial membrane (GO:0090151)2.72347487
149GPI anchor biosynthetic process (GO:0006506)2.72314004
150DNA damage response, detection of DNA damage (GO:0042769)2.68810242
151mitochondrial respiratory chain complex I assembly (GO:0032981)2.68583235
152NADH dehydrogenase complex assembly (GO:0010257)2.68583235
153mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.68583235
154platelet dense granule organization (GO:0060155)2.68088046
155protein K6-linked ubiquitination (GO:0085020)2.65891003
156glucosamine-containing compound catabolic process (GO:1901072)2.65853361
157ribosome assembly (GO:0042255)2.65670027
158DNA replication-independent nucleosome organization (GO:0034724)2.65493098
159DNA replication-independent nucleosome assembly (GO:0006336)2.65493098
160transcription from RNA polymerase I promoter (GO:0006360)2.64770690
161nucleotide transmembrane transport (GO:1901679)2.58429138
162spliceosomal snRNP assembly (GO:0000387)2.58189339
163DNA replication-dependent nucleosome organization (GO:0034723)2.52730150
164DNA replication-dependent nucleosome assembly (GO:0006335)2.52730150
165pseudouridine synthesis (GO:0001522)2.52279570
166telomere maintenance via telomere lengthening (GO:0010833)2.51118367
167maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.49459330
168RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)2.49299592
169rRNA modification (GO:0000154)2.48406753
170regulation of helicase activity (GO:0051095)2.46675379
171positive regulation of protein homodimerization activity (GO:0090073)2.46178590

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.29230468
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.78303589
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.71995162
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.36248405
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.69888559
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.45600215
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.38327573
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.37937180
9BP1_19119308_ChIP-ChIP_Hs578T_Human3.29446760
10E2F4_17652178_ChIP-ChIP_JURKAT_Human3.24915775
11CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.15421882
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.09852356
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.95205822
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.90682301
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.83107811
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.81551785
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.76704608
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.70162726
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.64598383
20VDR_23849224_ChIP-Seq_CD4+_Human2.53116609
21MYC_19030024_ChIP-ChIP_MESCs_Mouse2.52015560
22MYC_19079543_ChIP-ChIP_MESCs_Mouse2.51982603
23ELK1_19687146_ChIP-ChIP_HELA_Human2.50193591
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.48004021
25FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.39145325
26NOTCH1_21737748_ChIP-Seq_TLL_Human2.28477907
27MYC_18358816_ChIP-ChIP_MESCs_Mouse2.22403530
28FOXP3_21729870_ChIP-Seq_TREG_Human2.15411077
29DCP1A_22483619_ChIP-Seq_HELA_Human2.12328405
30TTF2_22483619_ChIP-Seq_HELA_Human2.07009288
31XRN2_22483619_ChIP-Seq_HELA_Human1.93994089
32EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.80782638
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.80228762
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.78031765
35NELFA_20434984_ChIP-Seq_ESCs_Mouse1.77251470
36* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.76624742
37E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74853750
38AR_21909140_ChIP-Seq_LNCAP_Human1.74722146
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.69237512
40PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.60749821
41MYC_18940864_ChIP-ChIP_HL60_Human1.59602032
42SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.57088690
43FOXM1_23109430_ChIP-Seq_U2OS_Human1.56128839
44IRF1_19129219_ChIP-ChIP_H3396_Human1.55456781
45SRF_21415370_ChIP-Seq_HL-1_Mouse1.52902117
46IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.51731670
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.48377430
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.47008851
49FUS_26573619_Chip-Seq_HEK293_Human1.41916968
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40176297
51YY1_21170310_ChIP-Seq_MESCs_Mouse1.39478123
52FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.39027068
53POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37814970
54E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.37625942
55* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.37549392
56CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.34148418
57RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33303821
58RBPJ_22232070_ChIP-Seq_NCS_Mouse1.32660711
59ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.32388197
60TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.32279101
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30324174
62FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.29910605
63EWS_26573619_Chip-Seq_HEK293_Human1.26957377
64MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.26026009
65POU5F1_16153702_ChIP-ChIP_HESCs_Human1.25900010
66PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.24836870
67E2F1_21310950_ChIP-Seq_MCF-7_Human1.24310406
68KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.23229265
69KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.23229265
70KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.23229265
71SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.22280119
72POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.21223119
73TP63_19390658_ChIP-ChIP_HaCaT_Human1.21118031
74ELK1_22589737_ChIP-Seq_MCF10A_Human1.20798477
75EGR1_19374776_ChIP-ChIP_THP-1_Human1.19777369
76KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.16435678
77IRF8_22096565_ChIP-ChIP_GC-B_Human1.14959225
78STAT4_19710469_ChIP-ChIP_TH1__Mouse1.13891926
79GABP_19822575_ChIP-Seq_HepG2_Human1.13630950
80MYCN_18555785_ChIP-Seq_MESCs_Mouse1.09642434
81CHD1_26751641_Chip-Seq_LNCaP_Human1.07458669
82TAF15_26573619_Chip-Seq_HEK293_Human1.04864172
83* SPI1_23547873_ChIP-Seq_NB4_Human1.03193617
84ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03104960
85PADI4_21655091_ChIP-ChIP_MCF-7_Human1.02033190
86* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99868855
87ESR1_15608294_ChIP-ChIP_MCF-7_Human0.99158224
88* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.99029576
89NANOG_18555785_ChIP-Seq_MESCs_Mouse0.97866978
90VDR_22108803_ChIP-Seq_LS180_Human0.94808464
91CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94662638
92RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.91013439
93SCL_19346495_ChIP-Seq_HPC-7_Human0.90657997
94FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.90463560
95CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89714044
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89442780
97* TFEB_21752829_ChIP-Seq_HELA_Human0.89065438
98IGF1R_20145208_ChIP-Seq_DFB_Human0.88507855
99CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88426803
100NANOG_16153702_ChIP-ChIP_HESCs_Human0.84359259
101CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.83657314
102PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.82491209
103HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.81995420
104SOX17_20123909_ChIP-Seq_XEN_Mouse0.81620145
105SALL1_21062744_ChIP-ChIP_HESCs_Human0.81161631
106PCGF2_27294783_Chip-Seq_ESCs_Mouse0.80831706
107FLI1_27457419_Chip-Seq_LIVER_Mouse0.80705249
108ZFP57_27257070_Chip-Seq_ESCs_Mouse0.80638874
109POU3F2_20337985_ChIP-ChIP_501MEL_Human0.79508989
110SOX2_18555785_ChIP-Seq_MESCs_Mouse0.78631376
111CIITA_25753668_ChIP-Seq_RAJI_Human0.77958715
112CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.76527770
113NANOG_21062744_ChIP-ChIP_HESCs_Human0.76255082
114TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.76190563
115BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.75447350
116KLF4_18555785_ChIP-Seq_MESCs_Mouse0.73758459
117FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.73753823
118MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.73173664
119ELF5_23300383_ChIP-Seq_T47D_Human0.73088259
120GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.73026945
121PKCTHETA_26484144_Chip-Seq_BREAST_Human0.70751712
122CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.70383848
123HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.68992833
124GATA1_22025678_ChIP-Seq_K562_Human0.67909221
125CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.67573960
126ZNF274_21170338_ChIP-Seq_K562_Hela0.66734274
127KDM5A_27292631_Chip-Seq_BREAST_Human0.66094518
128NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.66060105

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.81952550
2MP0008057_abnormal_DNA_replication4.01953911
3MP0004381_abnormal_hair_follicle3.37056989
4MP0003693_abnormal_embryo_hatching3.22212586
5MP0010094_abnormal_chromosome_stability2.87508441
6MP0005075_abnormal_melanosome_morpholog2.83339149
7MP0008058_abnormal_DNA_repair2.53270466
8MP0005409_darkened_coat_color2.49621485
9MP0008932_abnormal_embryonic_tissue2.47872718
10MP0003136_yellow_coat_color2.33590276
11MP0005174_abnormal_tail_pigmentation2.31357184
12MP0004133_heterotaxia2.29268491
13MP0003077_abnormal_cell_cycle2.23274241
14MP0004957_abnormal_blastocyst_morpholog2.23262232
15MP0002102_abnormal_ear_morphology2.16987685
16MP0003567_abnormal_fetal_cardiomyocyte1.98761871
17MP0003111_abnormal_nucleus_morphology1.92094240
18MP0002396_abnormal_hematopoietic_system1.89985235
19MP0002009_preneoplasia1.88978864
20MP0005671_abnormal_response_to1.85210383
21MP0001697_abnormal_embryo_size1.79657300
22MP0001188_hyperpigmentation1.79635588
23MP0004233_abnormal_muscle_weight1.77329643
24MP0006292_abnormal_olfactory_placode1.72376006
25MP0003011_delayed_dark_adaptation1.69329455
26MP0005084_abnormal_gallbladder_morpholo1.65604860
27MP0003763_abnormal_thymus_physiology1.64516875
28MP0000015_abnormal_ear_pigmentation1.63804401
29MP0001672_abnormal_embryogenesis/_devel1.63082556
30MP0005380_embryogenesis_phenotype1.63082556
31MP0003724_increased_susceptibility_to1.62863870
32MP0001293_anophthalmia1.62471712
33MP0001730_embryonic_growth_arrest1.62094392
34MP0001986_abnormal_taste_sensitivity1.61863350
35MP0003984_embryonic_growth_retardation1.59231832
36MP0002938_white_spotting1.55407504
37MP0002088_abnormal_embryonic_growth/wei1.55368721
38MP0010307_abnormal_tumor_latency1.54825936
39MP0003718_maternal_effect1.53013648
40MP0002638_abnormal_pupillary_reflex1.51149937
41MP0003123_paternal_imprinting1.51005548
42MP0002160_abnormal_reproductive_system1.44528468
43MP0002084_abnormal_developmental_patter1.44277518
44MP0002166_altered_tumor_susceptibility1.41815709
45MP0002877_abnormal_melanocyte_morpholog1.39535496
46MP0002095_abnormal_skin_pigmentation1.38689725
47MP0004185_abnormal_adipocyte_glucose1.37565089
48MP0001529_abnormal_vocalization1.37161007
49MP0002132_abnormal_respiratory_system1.36134732
50MP0002163_abnormal_gland_morphology1.34495057
51MP0005408_hypopigmentation1.34179792
52MP0008007_abnormal_cellular_replicative1.33128400
53MP0001661_extended_life_span1.31311143
54MP0008789_abnormal_olfactory_epithelium1.30696023
55MP0006035_abnormal_mitochondrial_morpho1.29962674
56MP0009333_abnormal_splenocyte_physiolog1.29289547
57MP0000920_abnormal_myelination1.29097360
58MP0001286_abnormal_eye_development1.27809511
59MP0004197_abnormal_fetal_growth/weight/1.26786865
60MP0009697_abnormal_copulation1.25499731
61MP0002080_prenatal_lethality1.25470939
62MP0001835_abnormal_antigen_presentation1.23956688
63MP0000428_abnormal_craniofacial_morphol1.23548609
64MP0001905_abnormal_dopamine_level1.22643698
65MP0002086_abnormal_extraembryonic_tissu1.22601751
66MP0002085_abnormal_embryonic_tissue1.21650649
67MP0005187_abnormal_penis_morphology1.20704855
68MP0003786_premature_aging1.20521413
69MP0008877_abnormal_DNA_methylation1.20247566
70MP0003221_abnormal_cardiomyocyte_apopto1.19284313
71MP0003937_abnormal_limbs/digits/tail_de1.19203593
72MP0002277_abnormal_respiratory_mucosa1.18163149
73MP0001800_abnormal_humoral_immune1.16354189
74MP0002006_tumorigenesis1.14358813
75MP0002234_abnormal_pharynx_morphology1.13433831
76MP0002398_abnormal_bone_marrow1.13139592
77MP0000383_abnormal_hair_follicle1.12647668
78MP0006036_abnormal_mitochondrial_physio1.11289633
79MP0002722_abnormal_immune_system1.11262806
80MP0002697_abnormal_eye_size1.10578720
81MP0000703_abnormal_thymus_morphology1.08910277
82MP0005000_abnormal_immune_tolerance1.08407246
83MP0002092_abnormal_eye_morphology1.07934915
84MP0002148_abnormal_hypersensitivity_rea1.07025047
85MP0002420_abnormal_adaptive_immunity1.05717888
86MP0000462_abnormal_digestive_system1.05379008
87MP0001853_heart_inflammation1.05329677
88MP0003950_abnormal_plasma_membrane1.05064294
89MP0002751_abnormal_autonomic_nervous1.04454359
90MP0001819_abnormal_immune_cell1.02823840
91MP0005389_reproductive_system_phenotype1.02384376
92MP0004808_abnormal_hematopoietic_stem1.01470517
93MP0001929_abnormal_gametogenesis1.01444980
94MP0001485_abnormal_pinna_reflex1.01273450
95MP0002723_abnormal_immune_serum1.00760975
96MP0000689_abnormal_spleen_morphology1.00447667
97MP0003938_abnormal_ear_development0.99438110
98MP0000465_gastrointestinal_hemorrhage0.98836056
99MP0002452_abnormal_antigen_presenting0.98237412
100MP0005076_abnormal_cell_differentiation0.98012652
101MP0005379_endocrine/exocrine_gland_phen0.97503103
102MP0001790_abnormal_immune_system0.96618746
103MP0005387_immune_system_phenotype0.96618746
104MP0000716_abnormal_immune_system0.96384623
105MP0003943_abnormal_hepatobiliary_system0.95431827
106MP0009785_altered_susceptibility_to0.95240189
107MP0002177_abnormal_outer_ear0.93756688
108MP0009672_abnormal_birth_weight0.93418433
109MP0000490_abnormal_crypts_of0.93218053
110MP0000613_abnormal_salivary_gland0.92328786
111MP0003787_abnormal_imprinting0.92017560
112MP0001145_abnormal_male_reproductive0.91863468
113MP0003806_abnormal_nucleotide_metabolis0.91369756
114MP0004142_abnormal_muscle_tone0.90286310
115MP0002249_abnormal_larynx_morphology0.89716421
116MP0005025_abnormal_response_to0.89061061
117MP0000372_irregular_coat_pigmentation0.88860223
118MP0000049_abnormal_middle_ear0.87171855
119MP0003880_abnormal_central_pattern0.86468402
120MP0000653_abnormal_sex_gland0.86312555
121MP0002429_abnormal_blood_cell0.86129432
122MP0002210_abnormal_sex_determination0.85865558
123MP0003890_abnormal_embryonic-extraembry0.85763142
124MP0010678_abnormal_skin_adnexa0.84954293
125MP0001919_abnormal_reproductive_system0.84898174
126MP0009703_decreased_birth_body0.83419304
127MP0002405_respiratory_system_inflammati0.81803559
128MP0010352_gastrointestinal_tract_polyps0.80836949
129MP0003121_genomic_imprinting0.80528451
130MP0006072_abnormal_retinal_apoptosis0.79754330
131MP0003315_abnormal_perineum_morphology0.79453886
132MP0009250_abnormal_appendicular_skeleto0.79161577
133MP0008995_early_reproductive_senescence0.79031450
134MP0005499_abnormal_olfactory_system0.77837232
135MP0005394_taste/olfaction_phenotype0.77837232
136MP0004147_increased_porphyrin_level0.77333628
137MP0002233_abnormal_nose_morphology0.76532986
138MP0000685_abnormal_immune_system0.76066969
139MP0002419_abnormal_innate_immunity0.75942665
140MP0000358_abnormal_cell_content/0.75449902
141MP0002019_abnormal_tumor_incidence0.74148458
142MP0002933_joint_inflammation0.73602605
143MP0000647_abnormal_sebaceous_gland0.71970208
144MP0003122_maternal_imprinting0.71560506
145MP0000350_abnormal_cell_proliferation0.71306129
146MP0000537_abnormal_urethra_morphology0.71047280
147MP0001324_abnormal_eye_pigmentation0.69829655
148MP0005266_abnormal_metabolism0.69807997
149MP0003942_abnormal_urinary_system0.69568025
150MP0000313_abnormal_cell_death0.68809292
151MP0002111_abnormal_tail_morphology0.66489869
152MP0006276_abnormal_autonomic_nervous0.66187717
153MP0000026_abnormal_inner_ear0.66111546
154MP0005391_vision/eye_phenotype0.64803391
155MP0001119_abnormal_female_reproductive0.64287370
156MP0003186_abnormal_redox_activity0.64030803
157MP0000566_synostosis0.63372320
158MP0003119_abnormal_digestive_system0.62925533
159MP0003755_abnormal_palate_morphology0.62876414
160MP0010630_abnormal_cardiac_muscle0.61502239
161MP0003698_abnormal_male_reproductive0.58715623
162MP0001186_pigmentation_phenotype0.58652128
163MP0003646_muscle_fatigue0.57945170

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.26947241
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.01672345
3Chromsome breakage (HP:0040012)4.00193745
4Aplastic anemia (HP:0001915)3.81309519
5Abnormality of cells of the erythroid lineage (HP:0012130)3.67012097
6Macrocytic anemia (HP:0001972)3.41601995
7Abnormality of the preputium (HP:0100587)3.34523883
83-Methylglutaconic aciduria (HP:0003535)3.30027798
9Abnormal number of erythroid precursors (HP:0012131)3.27802221
10Volvulus (HP:0002580)3.25204942
11Increased hepatocellular lipid droplets (HP:0006565)3.17763271
12Abnormal hemoglobin (HP:0011902)3.06010773
13Abnormality of chromosome stability (HP:0003220)3.00201735
14Acute necrotizing encephalopathy (HP:0006965)2.92327305
15Renal Fanconi syndrome (HP:0001994)2.89955794
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.88611185
17Pallor (HP:0000980)2.87851494
18Mitochondrial inheritance (HP:0001427)2.84039749
19Increased nuchal translucency (HP:0010880)2.81068654
20Meckel diverticulum (HP:0002245)2.81054059
21Asplenia (HP:0001746)2.78272824
22Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.71367684
23Aplasia/Hypoplasia of the sacrum (HP:0008517)2.70305978
24Ectopic kidney (HP:0000086)2.68294584
25Medulloblastoma (HP:0002885)2.68146393
26Parakeratosis (HP:0001036)2.67247808
27Abnormality of the ileum (HP:0001549)2.67217168
28Stenosis of the external auditory canal (HP:0000402)2.65976340
29Exertional dyspnea (HP:0002875)2.63931155
30Abnormality of the carotid arteries (HP:0005344)2.60304188
31Birth length less than 3rd percentile (HP:0003561)2.58393085
32Lipid accumulation in hepatocytes (HP:0006561)2.58248654
33Abnormality of the left ventricular outflow tract (HP:0011103)2.57572292
34Subaortic stenosis (HP:0001682)2.57572292
35Aplasia/Hypoplasia of the uvula (HP:0010293)2.56349266
36Triphalangeal thumb (HP:0001199)2.49680618
37Rough bone trabeculation (HP:0100670)2.47713973
38Nephroblastoma (Wilms tumor) (HP:0002667)2.45313041
39Aplasia/Hypoplasia of the spleen (HP:0010451)2.43901804
40Breast hypoplasia (HP:0003187)2.43414217
4111 pairs of ribs (HP:0000878)2.40442151
42Sloping forehead (HP:0000340)2.38185875
43Abnormal mitochondria in muscle tissue (HP:0008316)2.37008229
44Overlapping toe (HP:0001845)2.36877517
45Increased CSF lactate (HP:0002490)2.34690926
46Absent radius (HP:0003974)2.34097876
47Short thumb (HP:0009778)2.33978805
48Abnormality of cochlea (HP:0000375)2.30320317
49Progressive muscle weakness (HP:0003323)2.29698557
50Duodenal stenosis (HP:0100867)2.28821822
51Small intestinal stenosis (HP:0012848)2.28821822
52Irregular epiphyses (HP:0010582)2.28594846
53Abnormal lung lobation (HP:0002101)2.28115216
54Absent thumb (HP:0009777)2.25580263
55Fibular aplasia (HP:0002990)2.23952067
56Duplicated collecting system (HP:0000081)2.23611601
57Embryonal renal neoplasm (HP:0011794)2.22767007
58Progressive macrocephaly (HP:0004481)2.22401492
59Type I transferrin isoform profile (HP:0003642)2.22273693
60Hepatocellular necrosis (HP:0001404)2.20639039
61Cerebral hypomyelination (HP:0006808)2.19223768
62Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.16263288
63Abnormality of alanine metabolism (HP:0010916)2.16263288
64Hyperalaninemia (HP:0003348)2.16263288
65Aplasia involving forearm bones (HP:0009822)2.13917528
66Absent forearm bone (HP:0003953)2.13917528
67Fibular hypoplasia (HP:0003038)2.13876529
68Abnormality of the parietal bone (HP:0002696)2.13461302
69Myelodysplasia (HP:0002863)2.12593569
70Supernumerary spleens (HP:0009799)2.11604074
71Overfolded helix (HP:0000396)2.09109113
72Acute encephalopathy (HP:0006846)2.08506158
73Microvesicular hepatic steatosis (HP:0001414)2.06386267
74Renal cortical cysts (HP:0000803)2.05783089
75Hypoplasia of the radius (HP:0002984)2.04640990
76Anal stenosis (HP:0002025)2.02657208
77Partial duplication of thumb phalanx (HP:0009944)2.00928644
78Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.00800983
79Glossoptosis (HP:0000162)1.99837587
80Increased serum pyruvate (HP:0003542)1.98820819
81Pancreatic islet-cell hyperplasia (HP:0004510)1.97502374
82Abnormal number of incisors (HP:0011064)1.96760911
83Hypobetalipoproteinemia (HP:0003563)1.94226694
84Progressive external ophthalmoplegia (HP:0000590)1.92717023
85Multiple enchondromatosis (HP:0005701)1.92653123
86Absent rod-and cone-mediated responses on ERG (HP:0007688)1.91702293
87Abnormal trabecular bone morphology (HP:0100671)1.91623831
88Abnormality of the renal collecting system (HP:0004742)1.91456069
89Abnormality of glycolysis (HP:0004366)1.90995950
90Abnormality of the duodenum (HP:0002246)1.90119684
91Abnormality of the heme biosynthetic pathway (HP:0010472)1.89854383
92Acute myeloid leukemia (HP:0004808)1.89599529
93Clubbing of toes (HP:0100760)1.89516760
94Reduced antithrombin III activity (HP:0001976)1.89513350
95Short middle phalanx of the 5th finger (HP:0004220)1.88260942
96Partial agenesis of the corpus callosum (HP:0001338)1.87771200
97Hypoglycemic seizures (HP:0002173)1.87298757
98Abnormality of the pons (HP:0007361)1.87082574
99Colon cancer (HP:0003003)1.85984237
100Sensory axonal neuropathy (HP:0003390)1.85793311
101Anomalous pulmonary venous return (HP:0010772)1.84700371
102Patchy hypopigmentation of hair (HP:0011365)1.84192340
103Hypothermia (HP:0002045)1.83879156
104Cutaneous melanoma (HP:0012056)1.81615304
105Bone marrow hypocellularity (HP:0005528)1.81168992
106Pancytopenia (HP:0001876)1.80804328
107Oligohydramnios (HP:0001562)1.80237428
108Metaphyseal dysplasia (HP:0100255)1.79879682
109Cortical dysplasia (HP:0002539)1.79707048
110Neoplasm of the colon (HP:0100273)1.78931685
111Premature graying of hair (HP:0002216)1.78913417
112Microtia (HP:0008551)1.78685967
113Papillary thyroid carcinoma (HP:0002895)1.78025328
114Missing ribs (HP:0000921)1.77584341
115Severe combined immunodeficiency (HP:0004430)1.77419234
116Pancreatic cysts (HP:0001737)1.77128857
117IgM deficiency (HP:0002850)1.76747758
118Abnormality of DNA repair (HP:0003254)1.76207436
119Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.75518070
120Abnormally folded helix (HP:0008544)1.74623553
121Cerebellar dysplasia (HP:0007033)1.74483453
122Abnormality of methionine metabolism (HP:0010901)1.73515363
123Asymmetry of the thorax (HP:0001555)1.73461073
124Leukodystrophy (HP:0002415)1.73073315
125Cerebral edema (HP:0002181)1.72124342
126Decreased activity of mitochondrial respiratory chain (HP:0008972)1.71908989
127Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.71908989
128Exercise intolerance (HP:0003546)1.71617180
129White forelock (HP:0002211)1.71335383
130Abnormality of renal resorption (HP:0011038)1.70940277
131Abnormality of the labia minora (HP:0012880)1.70838324
132Horseshoe kidney (HP:0000085)1.70439426
133True hermaphroditism (HP:0010459)1.70239384
134Partial duplication of the phalanx of hand (HP:0009999)1.70154679
135Hypoplasia of the pons (HP:0012110)1.69942125
136Congenital malformation of the right heart (HP:0011723)1.69833904
137Double outlet right ventricle (HP:0001719)1.69833904
138Hypoplastic pelvis (HP:0008839)1.69634233
139Abnormality of the phalanges of the 2nd finger (HP:0009541)1.69556453
140Arteriovenous malformation (HP:0100026)1.69555158
141Rhabdomyosarcoma (HP:0002859)1.68244332
142Embryonal neoplasm (HP:0002898)1.68182826
143Cafe-au-lait spot (HP:0000957)1.66776377
144Facial hemangioma (HP:0000329)1.66736031
145Glioma (HP:0009733)1.66279696
146Capillary hemangiomas (HP:0005306)1.63689849
147Bilateral microphthalmos (HP:0007633)1.63182360
148Intestinal atresia (HP:0011100)1.62802190
149Pseudobulbar signs (HP:0002200)1.62018775
150Median cleft lip (HP:0000161)1.60098996
151Morphological abnormality of the inner ear (HP:0011390)1.60037369
152Abnormality of the nasal septum (HP:0000419)1.58760606
153Sandal gap (HP:0001852)1.57704398
154Premature ovarian failure (HP:0008209)1.56698664
155Choanal atresia (HP:0000453)1.55749666
156Septate vagina (HP:0001153)1.54308208
157Increased serum lactate (HP:0002151)1.54217595
158Proximal placement of thumb (HP:0009623)1.53943195
159Bifid tongue (HP:0010297)1.51465762
160Aplasia/Hypoplasia of the sternum (HP:0006714)1.50859630
161Thyroid carcinoma (HP:0002890)1.49408693
162Squamous cell carcinoma (HP:0002860)1.48928179
163Abnormality of the septum pellucidum (HP:0007375)1.48875609

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK43.36409964
2TLK13.12307812
3NME23.05911138
4MKNK22.91825893
5NEK12.84494927
6STK162.78008739
7EIF2AK12.61114215
8MKNK12.42256216
9VRK12.32471636
10TAF12.20955016
11WEE12.20535373
12SRPK12.18034073
13BUB12.17488460
14NEK22.04269436
15TXK1.92336453
16TNIK1.86090765
17MST41.78558289
18NUAK11.76846032
19PBK1.72518440
20NLK1.69283522
21STK391.68359868
22CDC71.66862715
23PASK1.56249486
24EIF2AK31.55433438
25BRD41.54654423
26IRAK31.50465711
27TSSK61.44717243
28MAP4K11.37978330
29PNCK1.37420890
30BCR1.37403921
31STK31.36711523
32BRSK21.36485179
33TEC1.34902304
34ZAK1.32570099
35CASK1.27667626
36PLK21.27202048
37CDK71.24417519
38ERBB31.20764444
39BLK1.18933387
40TTK1.15500378
41LATS11.14630851
42CLK11.12275344
43IRAK21.11879919
44BRSK11.11204339
45MAP3K141.09667265
46NEK61.09108515
47OXSR11.03548849
48PIM21.01365054
49PDK21.00777605
50EEF2K0.99568357
51MAPKAPK50.97863475
52PLK30.97271687
53RPS6KA40.95027921
54MAPK150.93788456
55TRIM280.89511237
56KIT0.88448883
57TESK20.86113253
58EIF2AK20.85992669
59VRK20.85838615
60STK40.84004081
61ATR0.83878719
62CAMK1G0.83667657
63IRAK10.83569236
64CHEK20.83039829
65YES10.82536964
66PLK10.81267058
67ADRBK20.80800601
68AURKB0.80790000
69ACVR1B0.80316785
70GRK70.78654927
71WNK40.78487806
72MAP3K100.76444023
73PLK40.75574315
74DYRK30.75210283
75CSNK1G30.74649261
76CSNK1G10.74192115
77LCK0.73925690
78BMPR20.73337383
79NME10.71878524
80BTK0.69788358
81BMPR1B0.69664429
82CDK40.68938695
83RPS6KB20.68857877
84CSNK2A20.68611168
85DYRK20.67964057
86DMPK0.66521539
87RPS6KA50.66468158
88CSNK1A1L0.64441641
89CAMK1D0.63878016
90PIK3CA0.63610856
91CDK80.63577316
92GRK60.63159528
93FGFR10.62488559
94CSNK2A10.61931904
95GRK10.61534253
96SCYL20.61303026
97CDK190.60959842
98PIM10.60717367
99IKBKB0.59817153
100STK100.59394270
101MAP3K20.56955662
102PKN10.56347721
103IKBKE0.56079371
104FES0.55087501
105ATM0.54567211
106CDK90.54480987
107CHEK10.54303986
108RPS6KB10.54246190
109LYN0.53512872
110CSK0.52714479
111CDK60.50858350
112TRPM70.50638115
113PRKCQ0.49567577
114WNK10.48024860
115CAMK2B0.46695392
116CCNB10.46442337
117CDK120.46379273
118MAPK130.44864244
119MST1R0.44726936
120PRKDC0.43544601
121ALK0.43280835
122CSNK1E0.43118112
123ITK0.42850343
124MAP3K120.42278389
125GSK3A0.42154228
126CDK30.41938243
127AURKA0.41712601
128STK240.41528095
129AKT30.41062756
130MARK30.39656968
131FLT30.38783380
132MAP3K80.38577608
133STK38L0.38533007
134CDK10.38290034
135OBSCN0.37216107
136UHMK10.37201014
137ICK0.37084019
138TIE10.37032372
139CDK20.36494296
140MAPK140.35330973
141AKT20.35256202
142MAP2K20.33674730
143KSR10.33624690
144ADRBK10.31854550
145ILK0.31761630
146MELK0.31325470
147RAF10.31152848
148MAP2K10.30606757
149MAP2K40.30381383
150ERBB40.29065386

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.08610774
2RNA polymerase_Homo sapiens_hsa030203.48682289
3DNA replication_Homo sapiens_hsa030303.30145550
4Mismatch repair_Homo sapiens_hsa034303.30093797
5Fanconi anemia pathway_Homo sapiens_hsa034603.07859189
6Homologous recombination_Homo sapiens_hsa034402.92143112
7Spliceosome_Homo sapiens_hsa030402.84113985
8Oxidative phosphorylation_Homo sapiens_hsa001902.79589963
9Protein export_Homo sapiens_hsa030602.75035906
10Proteasome_Homo sapiens_hsa030502.66388314
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.59235510
12Non-homologous end-joining_Homo sapiens_hsa034502.44988690
13Parkinsons disease_Homo sapiens_hsa050122.37070925
14Nucleotide excision repair_Homo sapiens_hsa034202.22940559
15Pyrimidine metabolism_Homo sapiens_hsa002402.02844747
16Basal transcription factors_Homo sapiens_hsa030222.00886098
17RNA transport_Homo sapiens_hsa030131.97510869
18Base excision repair_Homo sapiens_hsa034101.85507203
19Huntingtons disease_Homo sapiens_hsa050161.82865819
20RNA degradation_Homo sapiens_hsa030181.76258522
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.74778965
22Selenocompound metabolism_Homo sapiens_hsa004501.72649591
23Alzheimers disease_Homo sapiens_hsa050101.60138428
24Cysteine and methionine metabolism_Homo sapiens_hsa002701.55025426
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.54018921
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.44382166
27Cell cycle_Homo sapiens_hsa041101.43827515
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.43344248
29Primary immunodeficiency_Homo sapiens_hsa053401.39762056
30Graft-versus-host disease_Homo sapiens_hsa053321.31498848
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.29064488
32Propanoate metabolism_Homo sapiens_hsa006401.27501537
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.18443070
34Pyruvate metabolism_Homo sapiens_hsa006201.17496061
35Systemic lupus erythematosus_Homo sapiens_hsa053221.15872274
36mRNA surveillance pathway_Homo sapiens_hsa030151.14031587
37Purine metabolism_Homo sapiens_hsa002301.13271580
38Steroid biosynthesis_Homo sapiens_hsa001001.11848270
39Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.10880697
40p53 signaling pathway_Homo sapiens_hsa041151.07617415
41Sphingolipid metabolism_Homo sapiens_hsa006001.04546309
42Allograft rejection_Homo sapiens_hsa053301.03837194
43One carbon pool by folate_Homo sapiens_hsa006701.02544491
44Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01491084
45Hematopoietic cell lineage_Homo sapiens_hsa046401.01023773
46Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.97369191
47NF-kappa B signaling pathway_Homo sapiens_hsa040640.96625855
48Autoimmune thyroid disease_Homo sapiens_hsa053200.91141168
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90122947
50Folate biosynthesis_Homo sapiens_hsa007900.88311306
51Lysine degradation_Homo sapiens_hsa003100.87489912
52Intestinal immune network for IgA production_Homo sapiens_hsa046720.87146909
53Biosynthesis of amino acids_Homo sapiens_hsa012300.87001255
54Oocyte meiosis_Homo sapiens_hsa041140.86009138
55Butanoate metabolism_Homo sapiens_hsa006500.82069851
56Epstein-Barr virus infection_Homo sapiens_hsa051690.79572837
57Basal cell carcinoma_Homo sapiens_hsa052170.77676098
58Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77451256
59Arachidonic acid metabolism_Homo sapiens_hsa005900.76551935
60Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.73838872
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.70050144
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69497706
63Ether lipid metabolism_Homo sapiens_hsa005650.69326424
64Linoleic acid metabolism_Homo sapiens_hsa005910.69318363
65Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68844863
66Glutathione metabolism_Homo sapiens_hsa004800.67914721
67Measles_Homo sapiens_hsa051620.67075090
68Antigen processing and presentation_Homo sapiens_hsa046120.66030546
69Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.65246654
70Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.65115096
71Herpes simplex infection_Homo sapiens_hsa051680.64969266
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.64311465
73Fatty acid biosynthesis_Homo sapiens_hsa000610.64078215
74Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.63293267
75N-Glycan biosynthesis_Homo sapiens_hsa005100.63181787
76Carbon metabolism_Homo sapiens_hsa012000.61589378
77Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.60637596
78Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60441348
79Sulfur relay system_Homo sapiens_hsa041220.60028718
80Fatty acid metabolism_Homo sapiens_hsa012120.58877220
81Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58390636
82Fatty acid elongation_Homo sapiens_hsa000620.57033513
83Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53122847
84MicroRNAs in cancer_Homo sapiens_hsa052060.52776724
85Asthma_Homo sapiens_hsa053100.50569564
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48412106
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47811832
88Nitrogen metabolism_Homo sapiens_hsa009100.47326703
89Phototransduction_Homo sapiens_hsa047440.47192888
90Prostate cancer_Homo sapiens_hsa052150.46806875
91Rheumatoid arthritis_Homo sapiens_hsa053230.46453172
92Metabolic pathways_Homo sapiens_hsa011000.45860761
93Maturity onset diabetes of the young_Homo sapiens_hsa049500.45597712
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.44405929
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44038196
96Hippo signaling pathway_Homo sapiens_hsa043900.43875730
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43041558
98Cardiac muscle contraction_Homo sapiens_hsa042600.42067892
99Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42029248
100Hedgehog signaling pathway_Homo sapiens_hsa043400.41690926
101Fatty acid degradation_Homo sapiens_hsa000710.41325349
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40201355
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40057214
104Malaria_Homo sapiens_hsa051440.40043139
105Alcoholism_Homo sapiens_hsa050340.39878731
106Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.39670539
107NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38437831
108Colorectal cancer_Homo sapiens_hsa052100.36686107
109T cell receptor signaling pathway_Homo sapiens_hsa046600.36375631
110Retinol metabolism_Homo sapiens_hsa008300.36147291
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34495049
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34309284
1132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.34295996
114RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34164120
115Viral carcinogenesis_Homo sapiens_hsa052030.33421969
116Adherens junction_Homo sapiens_hsa045200.30557507
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.30147334
118Melanoma_Homo sapiens_hsa052180.30044551
119Drug metabolism - other enzymes_Homo sapiens_hsa009830.29895299
120Type I diabetes mellitus_Homo sapiens_hsa049400.29685207
121Leishmaniasis_Homo sapiens_hsa051400.28100808
122Small cell lung cancer_Homo sapiens_hsa052220.27808939
123Arginine biosynthesis_Homo sapiens_hsa002200.27686926
124Non-small cell lung cancer_Homo sapiens_hsa052230.27617733
125Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.27352073
126Histidine metabolism_Homo sapiens_hsa003400.27161384
127alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26276844
128ECM-receptor interaction_Homo sapiens_hsa045120.25541423
129Arginine and proline metabolism_Homo sapiens_hsa003300.24177180
130Peroxisome_Homo sapiens_hsa041460.23948679
131FoxO signaling pathway_Homo sapiens_hsa040680.23215494
132mTOR signaling pathway_Homo sapiens_hsa041500.22591477
133Vitamin B6 metabolism_Homo sapiens_hsa007500.19727519
134Jak-STAT signaling pathway_Homo sapiens_hsa046300.17865097
135Bladder cancer_Homo sapiens_hsa052190.16458110
136African trypanosomiasis_Homo sapiens_hsa051430.16233881
137Thyroid cancer_Homo sapiens_hsa052160.15968621
138Fat digestion and absorption_Homo sapiens_hsa049750.15200413
139Pertussis_Homo sapiens_hsa051330.14412153
140PI3K-Akt signaling pathway_Homo sapiens_hsa041510.13605667
141Serotonergic synapse_Homo sapiens_hsa047260.13496794
142Steroid hormone biosynthesis_Homo sapiens_hsa001400.13429642
143TGF-beta signaling pathway_Homo sapiens_hsa043500.13224988
144Pathways in cancer_Homo sapiens_hsa052000.12778960
145Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.12164438
146Wnt signaling pathway_Homo sapiens_hsa043100.11990542
147HTLV-I infection_Homo sapiens_hsa051660.11903472
148Cyanoamino acid metabolism_Homo sapiens_hsa004600.11584319

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