SNRNP70

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of erythrocyte differentiation (GO:0045647)5.46370443
2mannose metabolic process (GO:0006013)4.64582007
3pre-miRNA processing (GO:0031054)4.51374202
4peptidyl-lysine dimethylation (GO:0018027)4.02829110
5cytoskeletal anchoring at plasma membrane (GO:0007016)3.82457516
6negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.79663873
7positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.71337613
8sodium ion export (GO:0071436)3.70171482
9locomotory exploration behavior (GO:0035641)3.68240070
10negative regulation of histone methylation (GO:0031061)3.56674721
11positive regulation of histone deacetylation (GO:0031065)3.45541554
12histone H3-K4 trimethylation (GO:0080182)3.44386449
13positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.32444953
14histone H3-K4 methylation (GO:0051568)3.32209347
15positive regulation of RNA splicing (GO:0033120)3.30984194
16synaptic vesicle maturation (GO:0016188)3.28184939
17apoptotic process involved in morphogenesis (GO:0060561)3.20646174
18regulation of histone H3-K27 methylation (GO:0061085)3.20375825
19negative regulation of RNA splicing (GO:0033119)3.18894850
20regulation of short-term neuronal synaptic plasticity (GO:0048172)3.17876313
21layer formation in cerebral cortex (GO:0021819)3.17600483
22negative regulation of mRNA processing (GO:0050686)3.17369923
23establishment of nucleus localization (GO:0040023)3.16527493
24positive regulation of gamma-delta T cell activation (GO:0046645)3.14813126
25negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.13146370
26semaphorin-plexin signaling pathway (GO:0071526)3.12766336
27positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.09791479
28regulation of clathrin-mediated endocytosis (GO:2000369)3.08956724
29antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.08939414
30response to muramyl dipeptide (GO:0032495)3.08849079
31intracellular estrogen receptor signaling pathway (GO:0030520)3.08665274
32activation of Rac GTPase activity (GO:0032863)3.08408389
33mRNA splice site selection (GO:0006376)3.07753481
34cerebellar Purkinje cell differentiation (GO:0021702)3.07243410
35negative regulation of myotube differentiation (GO:0010832)3.06148228
36histone H4-K16 acetylation (GO:0043984)3.05717041
37regulation of translational termination (GO:0006449)3.05649272
38heterochromatin organization (GO:0070828)3.04311101
39stress granule assembly (GO:0034063)3.03315917
40cytoplasmic mRNA processing body assembly (GO:0033962)2.97479453
41histone H4 deacetylation (GO:0070933)2.97083218
423-UTR-mediated mRNA stabilization (GO:0070935)2.96014327
43regulation of glucose import in response to insulin stimulus (GO:2001273)2.95236316
44negative regulation of mRNA metabolic process (GO:1903312)2.94617412
45glucocorticoid receptor signaling pathway (GO:0042921)2.92493535
46adherens junction assembly (GO:0034333)2.90968221
47peptidyl-lysine trimethylation (GO:0018023)2.90575370
48activation of MAPKKK activity (GO:0000185)2.90009648
49antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.89579223
50RNA stabilization (GO:0043489)2.89448129
51mRNA stabilization (GO:0048255)2.89448129
52antigen processing and presentation of endogenous antigen (GO:0019883)2.88369188
53positive regulation of gene expression, epigenetic (GO:0045815)2.88038540
54regulation of ARF GTPase activity (GO:0032312)2.87231508
55chromatin silencing (GO:0006342)2.86896975
56positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.85996549
57positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.85082733
58NLS-bearing protein import into nucleus (GO:0006607)2.84987936
59histone lysine methylation (GO:0034968)2.84164422
60regulation of early endosome to late endosome transport (GO:2000641)2.83979942
61endothelial cell chemotaxis (GO:0035767)2.82108570
62mitotic G1 DNA damage checkpoint (GO:0031571)2.81148886
63regulation of extracellular matrix disassembly (GO:0010715)2.80145784
64regulation of ARF protein signal transduction (GO:0032012)2.79955184
65histone H3-K36 demethylation (GO:0070544)2.78883604
66spliceosomal tri-snRNP complex assembly (GO:0000244)2.77872815
67focal adhesion assembly (GO:0048041)2.77107554
68cell-substrate adherens junction assembly (GO:0007045)2.77107554
69negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.77100929
70negative regulation of cell killing (GO:0031342)2.77100929
71histone H3 deacetylation (GO:0070932)2.76953407
72regulation of chromatin binding (GO:0035561)2.76030164
73histone H4-K5 acetylation (GO:0043981)2.75218333
74histone H4-K8 acetylation (GO:0043982)2.75218333
75negative regulation of cell size (GO:0045792)2.73457619
76response to laminar fluid shear stress (GO:0034616)2.72352732
77cortical actin cytoskeleton organization (GO:0030866)2.72230915
78establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.71449998
79peptidyl-lysine methylation (GO:0018022)2.69538632
80positive regulation of synapse maturation (GO:0090129)2.68878013
81modulation by symbiont of host cellular process (GO:0044068)2.68392376
82regulation of type I interferon-mediated signaling pathway (GO:0060338)2.67812173
83peptidyl-tyrosine autophosphorylation (GO:0038083)2.66688305
84regulation of gamma-delta T cell activation (GO:0046643)2.65518646
85regulation of translational fidelity (GO:0006450)2.65152678
86nuclear pore complex assembly (GO:0051292)2.64758954
87maternal placenta development (GO:0001893)2.62928301
88regulation of mammary gland epithelial cell proliferation (GO:0033599)2.62591215
89positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.62471648
90negative regulation of fatty acid transport (GO:2000192)2.61385698
91modulation by virus of host process (GO:0019054)2.61165610
92protein localization to endosome (GO:0036010)2.60010635
93negative regulation of gene expression, epigenetic (GO:0045814)2.59926227
94histone methylation (GO:0016571)2.59844655
95synaptic vesicle docking involved in exocytosis (GO:0016081)2.58085033
96cellular potassium ion homeostasis (GO:0030007)2.57480377
97cell-cell junction maintenance (GO:0045217)2.57073011
98thymic T cell selection (GO:0045061)2.56567845
99epithelial cell differentiation involved in prostate gland development (GO:0060742)2.56257796
100cellular response to epidermal growth factor stimulus (GO:0071364)2.54895900
101neuromuscular process controlling balance (GO:0050885)2.53953477
102planar cell polarity pathway involved in neural tube closure (GO:0090179)2.53850590
103embryonic process involved in female pregnancy (GO:0060136)2.53685546
104histone H3-K9 demethylation (GO:0033169)2.53420635
105mitotic sister chromatid cohesion (GO:0007064)2.52258013
106nucleosome disassembly (GO:0006337)2.51168841
107protein-DNA complex disassembly (GO:0032986)2.51168841
108regulation of gamma-delta T cell differentiation (GO:0045586)2.49983804
109histone H4-K12 acetylation (GO:0043983)2.49595676
110insulin-like growth factor receptor signaling pathway (GO:0048009)2.49458550
111regulation of NFAT protein import into nucleus (GO:0051532)2.49140643
112positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.48930397
113positive thymic T cell selection (GO:0045059)2.48759808
114glial cell proliferation (GO:0014009)2.48675186
115stress fiber assembly (GO:0043149)2.47488572
116germinal center formation (GO:0002467)2.47463871
117regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.47407647
118alternative mRNA splicing, via spliceosome (GO:0000380)2.46771850
119regulation of monocyte differentiation (GO:0045655)2.46606127
120regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.45916284
121cellular response to virus (GO:0098586)2.45579555
122positive regulation of Rap GTPase activity (GO:0032854)2.45409480
123positive regulation of blood vessel endothelial cell migration (GO:0043536)2.45157331
124negative thymic T cell selection (GO:0045060)2.43330498
125mitotic G1/S transition checkpoint (GO:0044819)2.43153088
126gene silencing (GO:0016458)2.41815750
127cell volume homeostasis (GO:0006884)2.41735701
128regulation of histone H3-K4 methylation (GO:0051569)2.41339132
129histone lysine demethylation (GO:0070076)2.40938061
130positive regulation of Cdc42 GTPase activity (GO:0043089)2.40370508
131positive regulation of protein dephosphorylation (GO:0035307)2.39793585
132regulation of Rap GTPase activity (GO:0032317)2.39695366
133nuclear pore organization (GO:0006999)2.37759832
134regulation of RNA export from nucleus (GO:0046831)2.37252312
135histone H4 acetylation (GO:0043967)2.37053776
136cell communication by electrical coupling (GO:0010644)2.36678819
137negative regulation of translation, ncRNA-mediated (GO:0040033)2.35632101
138regulation of translation, ncRNA-mediated (GO:0045974)2.35632101
139negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.35632101
140negative regulation of nucleotide catabolic process (GO:0030812)2.34872914
141cell-substrate junction assembly (GO:0007044)2.34840510
142positive regulation of CREB transcription factor activity (GO:0032793)2.34746268
143cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.34710146
144T cell selection (GO:0045058)2.34149002
145NIK/NF-kappaB signaling (GO:0038061)2.33926522
146basement membrane organization (GO:0071711)2.33491000
147regulation of histone H3-K9 methylation (GO:0051570)2.33295272
148signal complex assembly (GO:0007172)2.32056623
149positive T cell selection (GO:0043368)2.31341389
150G1 DNA damage checkpoint (GO:0044783)2.31325694
151regulation of mRNA stability (GO:0043488)2.31157496
152negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.30924032
153corticosteroid receptor signaling pathway (GO:0031958)2.30601218
154activation of JUN kinase activity (GO:0007257)2.30360238
155regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.29417450
156regulation of nucleobase-containing compound transport (GO:0032239)2.29389311
157antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.29112617
158B cell receptor signaling pathway (GO:0050853)2.28609130
159detection of bacterium (GO:0016045)2.28466573
160cellular hyperosmotic response (GO:0071474)2.28087961
161barbed-end actin filament capping (GO:0051016)2.26380219
162histone demethylation (GO:0016577)2.25469220
163regulation of extracellular matrix organization (GO:1903053)2.22796609
164positive regulation of receptor recycling (GO:0001921)2.22226328
165atrioventricular valve morphogenesis (GO:0003181)2.22065830
166negative regulation of toll-like receptor signaling pathway (GO:0034122)2.21262133
167retrograde transport, endosome to Golgi (GO:0042147)2.20466712
168positive regulation of protein deacetylation (GO:0090312)2.20360906
169vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.19990717
170regulation of necroptotic process (GO:0060544)2.19943732

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human3.98764831
2MYC_22102868_ChIP-Seq_BL_Human3.77595651
3E2F7_22180533_ChIP-Seq_HELA_Human3.71566348
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.39897201
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.23124771
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.17847863
7KDM2B_26808549_Chip-Seq_DND41_Human2.96431670
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.68987996
9TCF7_22412390_ChIP-Seq_EML_Mouse2.60532340
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.59303671
11KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.59173611
12ZFP281_18757296_ChIP-ChIP_E14_Mouse2.58248842
13KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.54468432
14* ZFP281_27345836_Chip-Seq_ESCs_Mouse2.47694709
15* VDR_21846776_ChIP-Seq_THP-1_Human2.32681729
16KDM2B_26808549_Chip-Seq_K562_Human2.23196828
17RARG_19884340_ChIP-ChIP_MEFs_Mouse2.22913849
18KDM2B_26808549_Chip-Seq_JURKAT_Human2.20900569
19ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.16789820
20* DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.05617850
21NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.03873844
22LXR_22292898_ChIP-Seq_THP-1_Human2.00938739
23SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.99635533
24RARB_27405468_Chip-Seq_BRAIN_Mouse1.97029567
25ELK3_25401928_ChIP-Seq_HUVEC_Human1.94047332
26WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.93719839
27CIITA_25753668_ChIP-Seq_RAJI_Human1.89381788
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.83217710
29EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.81174759
30UTX_26944678_Chip-Seq_JUKART_Human1.79855655
31DROSHA_22980978_ChIP-Seq_HELA_Human1.71579291
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69663218
33PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.65110625
34TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.64820872
35P300_27058665_Chip-Seq_ZR-75-30cells_Human1.63560290
36ZNF263_19887448_ChIP-Seq_K562_Human1.61645947
37CREB1_26743006_Chip-Seq_LNCaP_Human1.61403060
38STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.59374565
39RACK7_27058665_Chip-Seq_MCF-7_Human1.57938719
40DNAJC2_21179169_ChIP-ChIP_NT2_Human1.56289516
41MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.55507676
42* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.55028378
43* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.53433070
44TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.53143504
45MAF_26560356_Chip-Seq_TH1_Human1.51501531
46GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.50995536
47TET1_21451524_ChIP-Seq_MESCs_Mouse1.49390131
48CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.48576958
49KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.48384363
50SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.48199309
51EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.47658686
52P68_20966046_ChIP-Seq_HELA_Human1.44210342
53E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.41522964
54IKZF1_21737484_ChIP-ChIP_HCT116_Human1.41464304
55TP63_17297297_ChIP-ChIP_HaCaT_Human1.41305502
56* RUNX1_22412390_ChIP-Seq_EML_Mouse1.40722673
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.38426043
58SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.38046030
59NCOR1_26117541_ChIP-Seq_K562_Human1.36096321
60SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.34511141
61CLOCK_20551151_ChIP-Seq_293T_Human1.32283881
62KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.30274421
63UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.29248828
64ERG_21242973_ChIP-ChIP_JURKAT_Human1.26280150
65BRD4_27068464_Chip-Seq_AML-cells_Mouse1.25687242
66* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.25225571
67RUNX1_27514584_Chip-Seq_MCF-7_Human1.24214986
68TP53_22127205_ChIP-Seq_IMR90_Human1.23667345
69ESR1_15608294_ChIP-ChIP_MCF-7_Human1.23371027
70ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.23259505
71FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.21995672
72SRY_22984422_ChIP-ChIP_TESTIS_Rat1.21209416
73* PKCTHETA_26484144_Chip-Seq_BREAST_Human1.20562755
74CTCF_27219007_Chip-Seq_ERYTHROID_Human1.19678403
75GATA1_19941827_ChIP-Seq_MEL_Mouse1.19456734
76MAF_26560356_Chip-Seq_TH2_Human1.19170380
77BCOR_27268052_Chip-Seq_Bcells_Human1.17685029
78SMC4_20622854_ChIP-Seq_HELA_Human1.17443015
79* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17180144
80KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.16868056
81MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.16770915
82RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.14624953
83CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.13745878
84ATF3_27146783_Chip-Seq_COLON_Human1.13177536
85ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.13036621
86GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12752640
87CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.11418420
88MYC_19079543_ChIP-ChIP_MESCs_Mouse1.10844828
89THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.10723232
90E2F4_17652178_ChIP-ChIP_JURKAT_Human1.10506337
91PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10026509
92VDR_24763502_ChIP-Seq_THP-1_Human1.08719865
93RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.08657839
94SA1_27219007_Chip-Seq_ERYTHROID_Human1.07763196
95SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06811309
96DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.05597873
97MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.05546737
98TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05501890
99NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05255748
100BCL6_27268052_Chip-Seq_Bcells_Human1.04919662
101TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03682888
102NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.03675178
103BP1_19119308_ChIP-ChIP_Hs578T_Human1.03547510
104SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.03113955
105PU.1_20513432_ChIP-Seq_Bcells_Mouse1.01251016
106SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.00989972
107POU5F1_16518401_ChIP-PET_MESCs_Mouse1.00763800
108ELF1_20517297_ChIP-Seq_JURKAT_Human1.00232878
109SCL_19346495_ChIP-Seq_HPC-7_Human0.99055138
110NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.98860901
111FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.97016227
112CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.96832708
113* TP63_22573176_ChIP-Seq_HFKS_Human0.96363993
114TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.95630039
115SPI1_23127762_ChIP-Seq_K562_Human0.95344800
116NANOG_21062744_ChIP-ChIP_HESCs_Human0.94271683
117GATA1_19941826_ChIP-Seq_K562_Human0.93750700
118OCT4_19829295_ChIP-Seq_ESCs_Human0.93626391
119* CHD1_26751641_Chip-Seq_LNCaP_Human0.93528818
120ESR2_21235772_ChIP-Seq_MCF-7_Human0.92410643
121CTCF_26484167_Chip-Seq_Bcells_Mouse0.92131704
122SA1_27219007_Chip-Seq_Bcells_Human0.91995893
123CTCF_21964334_ChIP-Seq_BJAB-B_Human0.91272274
124RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90705900
125CTCF_27219007_Chip-Seq_Bcells_Human0.89990063
126E2F1_21310950_ChIP-Seq_MCF-7_Human0.88590548
127VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.88557349
128CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.87513294
129PHF8_20622854_ChIP-Seq_HELA_Human0.87470957
130ISL1_27105846_Chip-Seq_CPCs_Mouse0.86791721
131RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.85176701
132MYB_26560356_Chip-Seq_TH1_Human0.84536519
133SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.83557592
134* KDM5A_27292631_Chip-Seq_BREAST_Human0.83503382
135WT1_25993318_ChIP-Seq_PODOCYTE_Human0.82907005

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.00762563
2MP0003705_abnormal_hypodermis_morpholog3.20225499
3MP0003172_abnormal_lysosome_physiology2.88664536
4MP0005076_abnormal_cell_differentiation2.87966616
5MP0005058_abnormal_lysosome_morphology2.83969577
6MP0003436_decreased_susceptibility_to2.73048298
7MP0008961_abnormal_basal_metabolism2.70760359
8MP0008260_abnormal_autophagy2.35689380
9MP0003283_abnormal_digestive_organ2.33125388
10MP0000569_abnormal_digit_pigmentation2.25778965
11MP0010234_abnormal_vibrissa_follicle2.22647767
12MP0003111_abnormal_nucleus_morphology2.21071118
13MP0003787_abnormal_imprinting2.14744799
14MP0005451_abnormal_body_composition2.10449922
15MP0010352_gastrointestinal_tract_polyps2.02495719
16MP0001348_abnormal_lacrimal_gland2.01893630
17MP0002249_abnormal_larynx_morphology1.97653341
18MP0003300_gastrointestinal_ulcer1.96240586
19MP0001849_ear_inflammation1.96170340
20MP0009278_abnormal_bone_marrow1.87445496
21MP0005409_darkened_coat_color1.86723204
22MP0002653_abnormal_ependyma_morphology1.84930635
23MP0000678_abnormal_parathyroid_gland1.84363375
24MP0000537_abnormal_urethra_morphology1.81441761
25MP0003279_aneurysm1.74041323
26MP0003123_paternal_imprinting1.70944962
27MP0003635_abnormal_synaptic_transmissio1.70527827
28MP0004947_skin_inflammation1.68438344
29MP0003329_amyloid_beta_deposits1.65475155
30MP0003690_abnormal_glial_cell1.65230179
31MP0000733_abnormal_muscle_development1.59496204
32MP0001958_emphysema1.56037190
33MP0001730_embryonic_growth_arrest1.53743665
34MP0004197_abnormal_fetal_growth/weight/1.53099065
35MP0003453_abnormal_keratinocyte_physiol1.52415638
36MP0008569_lethality_at_weaning1.51862803
37MP0002084_abnormal_developmental_patter1.51380962
38MP0003191_abnormal_cellular_cholesterol1.47503222
39MP0005423_abnormal_somatic_nervous1.46937768
40MP0003303_peritoneal_inflammation1.45165000
41MP0004885_abnormal_endolymph1.44889418
42MP0003045_fibrosis1.40758300
43MP0004185_abnormal_adipocyte_glucose1.39276623
44MP0000428_abnormal_craniofacial_morphol1.39203142
45MP0009840_abnormal_foam_cell1.38543338
46MP0000350_abnormal_cell_proliferation1.36274057
47MP0000858_altered_metastatic_potential1.34959151
48MP0000685_abnormal_immune_system1.34935985
49MP0003121_genomic_imprinting1.34062408
50MP0002085_abnormal_embryonic_tissue1.33897079
51MP0010307_abnormal_tumor_latency1.33257876
52MP0005187_abnormal_penis_morphology1.32135725
53MP0003566_abnormal_cell_adhesion1.31072457
54MP0003119_abnormal_digestive_system1.29938646
55MP0005623_abnormal_meninges_morphology1.28458941
56MP0009333_abnormal_splenocyte_physiolog1.27877149
57MP0003077_abnormal_cell_cycle1.27855492
58MP0000703_abnormal_thymus_morphology1.27406209
59MP0005380_embryogenesis_phenotype1.27141613
60MP0001672_abnormal_embryogenesis/_devel1.27141613
61MP0002877_abnormal_melanocyte_morpholog1.26887766
62MP0008770_decreased_survivor_rate1.25480249
63MP0001800_abnormal_humoral_immune1.25375288
64MP0005025_abnormal_response_to1.24707253
65MP0005000_abnormal_immune_tolerance1.23784896
66MP0002089_abnormal_postnatal_growth/wei1.23544900
67MP0001790_abnormal_immune_system1.23077071
68MP0005387_immune_system_phenotype1.23077071
69MP0002822_catalepsy1.22488397
70MP0002933_joint_inflammation1.22179288
71MP0004381_abnormal_hair_follicle1.22050121
72MP0004808_abnormal_hematopoietic_stem1.22037229
73MP0009780_abnormal_chondrocyte_physiolo1.21556927
74MP0002086_abnormal_extraembryonic_tissu1.21459427
75MP0003115_abnormal_respiratory_system1.20706841
76MP0003984_embryonic_growth_retardation1.18389324
77MP0002088_abnormal_embryonic_growth/wei1.18302312
78MP0002998_abnormal_bone_remodeling1.17870580
79MP0002419_abnormal_innate_immunity1.16102673
80MP0009384_cardiac_valve_regurgitation1.15850185
81MP0003861_abnormal_nervous_system1.15832552
82MP0002909_abnormal_adrenal_gland1.15827682
83MP0008438_abnormal_cutaneous_collagen1.15546957
84MP0000003_abnormal_adipose_tissue1.14508068
85MP0009672_abnormal_birth_weight1.13250236
86MP0010155_abnormal_intestine_physiology1.13173459
87MP0002234_abnormal_pharynx_morphology1.12218878
88MP0004233_abnormal_muscle_weight1.11328636
89MP0009703_decreased_birth_body1.11159020
90MP0001697_abnormal_embryo_size1.10735030
91MP0002398_abnormal_bone_marrow1.10452906
92MP0002080_prenatal_lethality1.10114534
93MP0004858_abnormal_nervous_system1.09603848
94MP0004811_abnormal_neuron_physiology1.07251142
95MP0001533_abnormal_skeleton_physiology1.07079145
96MP0002925_abnormal_cardiovascular_devel1.05795471
97MP0002420_abnormal_adaptive_immunity1.05564059
98MP0001819_abnormal_immune_cell1.04856754
99MP0010094_abnormal_chromosome_stability1.04397448
100MP0005397_hematopoietic_system_phenotyp1.03755605
101MP0001545_abnormal_hematopoietic_system1.03755605
102MP0001835_abnormal_antigen_presentation1.03541603
103MP0003935_abnormal_craniofacial_develop1.03525390
104MP0001873_stomach_inflammation1.02933767
105MP0000767_abnormal_smooth_muscle1.02407183
106MP0009046_muscle_twitch1.01832625
107MP0005375_adipose_tissue_phenotype1.01384513
108MP0000604_amyloidosis1.00001697
109MP0002063_abnormal_learning/memory/cond0.98710546
110MP0002723_abnormal_immune_serum0.98692525
111MP0005023_abnormal_wound_healing0.97974052
112MP0000955_abnormal_spinal_cord0.97731777
113MP0010630_abnormal_cardiac_muscle0.97194888
114MP0000751_myopathy0.97114496
115MP0000716_abnormal_immune_system0.95490027
116MP0002152_abnormal_brain_morphology0.95099441
117MP0004145_abnormal_muscle_electrophysio0.94901370
118MP0002452_abnormal_antigen_presenting0.94610686
119MP0010030_abnormal_orbit_morphology0.94438974
120MP0003183_abnormal_peptide_metabolism0.92347254
121MP0004130_abnormal_muscle_cell0.92332805
122MP0006138_congestive_heart_failure0.91411961
123MP0005621_abnormal_cell_physiology0.90953381
124MP0002396_abnormal_hematopoietic_system0.90733369
125MP0004087_abnormal_muscle_fiber0.90368598
126MP0003763_abnormal_thymus_physiology0.90030190
127MP0000747_muscle_weakness0.89888860
128MP0001784_abnormal_fluid_regulation0.86765615
129MP0005360_urolithiasis0.86619607
130MP0003634_abnormal_glial_cell0.86400599
131MP0003866_abnormal_defecation0.86315554
132MP0002405_respiratory_system_inflammati0.86312124
133MP0004957_abnormal_blastocyst_morpholog0.86287616
134MP0000534_abnormal_ureter_morphology0.86174479
135MP0003693_abnormal_embryo_hatching0.85928878
136MP0003075_altered_response_to0.85422906
137MP0002429_abnormal_blood_cell0.84342329
138MP0001851_eye_inflammation0.83551203
139MP0002796_impaired_skin_barrier0.83124202
140MP0002064_seizures0.82497525
141MP0002722_abnormal_immune_system0.82392699
142MP0005670_abnormal_white_adipose0.81936777
143MP0002697_abnormal_eye_size0.81428762
144MP0004510_myositis0.81419470
145MP0003385_abnormal_body_wall0.81121164
146MP0001853_heart_inflammation0.81075092
147MP0009745_abnormal_behavioral_response0.80981405
148MP0000759_abnormal_skeletal_muscle0.80564992
149MP0005464_abnormal_platelet_physiology0.80381787
150MP0005666_abnormal_adipose_tissue0.79398318
151MP0000266_abnormal_heart_morphology0.78622036
152MP0003879_abnormal_hair_cell0.78424332
153MP0001299_abnormal_eye_distance/0.77895568
154MP0003091_abnormal_cell_migration0.77745744
155MP0008874_decreased_physiological_sensi0.76900833
156MP0002092_abnormal_eye_morphology0.75759162
157MP0002081_perinatal_lethality0.75406741
158MP0008877_abnormal_DNA_methylation0.74750370
159MP0000467_abnormal_esophagus_morphology0.74439734
160MP0003122_maternal_imprinting0.73835616
161MP0010769_abnormal_survival0.72886916
162MP0000681_abnormal_thyroid_gland0.72027885
163MP0003890_abnormal_embryonic-extraembry0.72025880
164MP0010678_abnormal_skin_adnexa0.71892592
165MP0002269_muscular_atrophy0.71359476
166MP0002970_abnormal_white_adipose0.70455553
167MP0010768_mortality/aging0.70085035
168MP0004270_analgesia0.69199588
169MP0005390_skeleton_phenotype0.69090298

Predicted human phenotypes

RankGene SetZ-score
1Obstructive sleep apnea (HP:0002870)4.50510343
2Hyperacusis (HP:0010780)4.15837437
3Broad face (HP:0000283)3.44326394
4Cerebral aneurysm (HP:0004944)3.31877873
5Insomnia (HP:0100785)3.22752488
6Elfin facies (HP:0004428)3.16982546
7Abnormality of the lower motor neuron (HP:0002366)3.11830887
8Shallow orbits (HP:0000586)2.99909194
9Pointed chin (HP:0000307)2.98595211
10Renovascular hypertension (HP:0100817)2.87088431
11Macroorchidism (HP:0000053)2.85836880
12Renal duplication (HP:0000075)2.79461384
13Abnormality of the fingertips (HP:0001211)2.78226967
14Overriding aorta (HP:0002623)2.77393570
15Ependymoma (HP:0002888)2.76483772
16Eczematoid dermatitis (HP:0000976)2.72880292
17Protrusio acetabuli (HP:0003179)2.63487119
18Dysmetric saccades (HP:0000641)2.62691371
19Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.58423446
20Short 4th metacarpal (HP:0010044)2.58423446
21Colitis (HP:0002583)2.57937316
22Thin bony cortex (HP:0002753)2.56641268
23Increased nuchal translucency (HP:0010880)2.53505898
24Cellulitis (HP:0100658)2.50928579
25Abnormality of the astrocytes (HP:0100707)2.50337221
26Astrocytoma (HP:0009592)2.50337221
27Heterotopia (HP:0002282)2.49601648
28Neoplasm of the heart (HP:0100544)2.46658527
29Hemiplegia (HP:0002301)2.44610195
30Cervical subluxation (HP:0003308)2.38878172
31Distal upper limb amyotrophy (HP:0007149)2.37325663
32Upper limb amyotrophy (HP:0009129)2.37325663
33Stridor (HP:0010307)2.37073948
34Biconcave vertebral bodies (HP:0004586)2.35872118
35Pseudobulbar signs (HP:0002200)2.34830965
36Bowel diverticulosis (HP:0005222)2.34324900
37Annular pancreas (HP:0001734)2.31393964
38Disproportionate tall stature (HP:0001519)2.31105667
39Increased connective tissue (HP:0009025)2.30324805
40Increased IgE level (HP:0003212)2.29636824
41Obsessive-compulsive behavior (HP:0000722)2.27480449
42Supranuclear gaze palsy (HP:0000605)2.24635584
43Flat cornea (HP:0007720)2.22604968
44Mitral regurgitation (HP:0001653)2.22581204
45Ankyloglossia (HP:0010296)2.21871401
46Metaphyseal cupping (HP:0003021)2.20653986
47Emphysema (HP:0002097)2.20554005
48Centrally nucleated skeletal muscle fibers (HP:0003687)2.16838149
49Trigonocephaly (HP:0000243)2.14283340
50Gastrointestinal inflammation (HP:0004386)2.12024550
51J-shaped sella turcica (HP:0002680)2.11842835
52Vertebral arch anomaly (HP:0008438)2.09998508
53Neurofibrillary tangles (HP:0002185)2.09781499
54Hand muscle atrophy (HP:0009130)2.09190239
55Enlarged penis (HP:0000040)2.08686927
56Supernumerary ribs (HP:0005815)2.08149204
57Hemorrhage of the eye (HP:0011885)2.08004579
58Cerebral inclusion bodies (HP:0100314)2.07781293
59Polygenic inheritance (HP:0010982)2.05509342
60Long eyelashes (HP:0000527)2.05150245
61Abnormality of oral frenula (HP:0000190)2.04341880
62Increased variability in muscle fiber diameter (HP:0003557)2.04050316
63Abnormality of the 4th metacarpal (HP:0010012)2.03727402
64Gastrointestinal stroma tumor (HP:0100723)2.03160215
65Abnormality of the diencephalon (HP:0010662)2.02023211
66Glioma (HP:0009733)2.01231673
67Flat acetabular roof (HP:0003180)1.99080204
68Anal stenosis (HP:0002025)1.98307465
69Action tremor (HP:0002345)1.97345116
70Segmental peripheral demyelination/remyelination (HP:0003481)1.96534177
71Basal cell carcinoma (HP:0002671)1.96408798
72Bronchomalacia (HP:0002780)1.94946010
73Narrow palate (HP:0000189)1.94375555
74Urethral obstruction (HP:0000796)1.94367880
75Genetic anticipation (HP:0003743)1.94336842
76Deep venous thrombosis (HP:0002625)1.93987303
77Broad palm (HP:0001169)1.93860071
78Abnormality of the thoracic spine (HP:0100711)1.93589025
79Dysostosis multiplex (HP:0000943)1.93289797
80Broad metatarsal (HP:0001783)1.91852065
81Bladder diverticulum (HP:0000015)1.91687010
82Dislocated radial head (HP:0003083)1.91549860
83Impaired smooth pursuit (HP:0007772)1.90200085
84Neuronal loss in central nervous system (HP:0002529)1.88788093
85Neoplasm of the oral cavity (HP:0100649)1.88614055
86Resting tremor (HP:0002322)1.86404230
87Spinal canal stenosis (HP:0003416)1.86183863
88Thin ribs (HP:0000883)1.86141044
89Gingivitis (HP:0000230)1.85802630
90Nuclear cataract (HP:0100018)1.84749404
91Ulnar bowing (HP:0003031)1.83279467
92Aneurysm (HP:0002617)1.83187940
93Skin tags (HP:0010609)1.83141553
94Broad thumb (HP:0011304)1.81717479
95Lymphangioma (HP:0100764)1.81439172
96Spinal cord lesions (HP:0100561)1.81252116
97Syringomyelia (HP:0003396)1.81252116
98Arnold-Chiari malformation (HP:0002308)1.81092234
99Onion bulb formation (HP:0003383)1.80255601
100Milia (HP:0001056)1.79784530
101Inflammation of the large intestine (HP:0002037)1.79713331
102Ankle clonus (HP:0011448)1.78765016
103Supernumerary bones of the axial skeleton (HP:0009144)1.77962643
104Abnormality of ocular smooth pursuit (HP:0000617)1.77435478
105Abnormality of the Achilles tendon (HP:0005109)1.76463853
106Abnormality of the radial head (HP:0003995)1.76442289
107Sacral dimple (HP:0000960)1.75506337
108Short phalanx of the thumb (HP:0009660)1.74573983
109Aqueductal stenosis (HP:0002410)1.74318661
110Abnormality of skeletal muscle fiber size (HP:0012084)1.74036539
111Difficulty climbing stairs (HP:0003551)1.73856013
112Interstitial pulmonary disease (HP:0006530)1.73564972
113Premature rupture of membranes (HP:0001788)1.72744207
114Myopathic facies (HP:0002058)1.72708086
115Mitral valve prolapse (HP:0001634)1.72647498
116Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.72398578
117Slow saccadic eye movements (HP:0000514)1.70508335
118Thoracic kyphosis (HP:0002942)1.69451763
119Sandal gap (HP:0001852)1.68506593
120Abnormality of complement system (HP:0005339)1.67548749
121Gastrointestinal carcinoma (HP:0002672)1.67179241
122Malignant gastrointestinal tract tumors (HP:0006749)1.67179241
123Mildly elevated creatine phosphokinase (HP:0008180)1.67029244
124Vertebral compression fractures (HP:0002953)1.66915941
125Lower limb amyotrophy (HP:0007210)1.66417260
126Atelectasis (HP:0100750)1.65587345
127Malnutrition (HP:0004395)1.64332090
128High pitched voice (HP:0001620)1.64226557
129Distal lower limb muscle weakness (HP:0009053)1.63929213
130Systemic lupus erythematosus (HP:0002725)1.62991484
131Deviation of the hallux (HP:0010051)1.62953720
132Agammaglobulinemia (HP:0004432)1.62931313
133Aortic aneurysm (HP:0004942)1.62658100
134Increased density of long bones (HP:0006392)1.62571469
135Deep palmar crease (HP:0006191)1.61931292
136Hypercortisolism (HP:0001578)1.61922933
137Impaired social interactions (HP:0000735)1.61868690
138Abnormal social behavior (HP:0012433)1.61868690
139Mediastinal lymphadenopathy (HP:0100721)1.61644891
140Prominent nose (HP:0000448)1.61100973
141Genu recurvatum (HP:0002816)1.60988041
142Germ cell neoplasia (HP:0100728)1.60875634
143Mucopolysacchariduria (HP:0008155)1.60282401
144Urinary glycosaminoglycan excretion (HP:0003541)1.60282401
145Focal seizures (HP:0007359)1.59982487
146Medulloblastoma (HP:0002885)1.59834600
147Achilles tendon contracture (HP:0001771)1.59666396
148Broad distal phalanx of finger (HP:0009836)1.59665880
149Fragile skin (HP:0001030)1.59535750
150Neoplasm of striated muscle (HP:0009728)1.59419862
151Megalocornea (HP:0000485)1.59397328
152Easy fatigability (HP:0003388)1.59317419
153Exercise-induced myalgia (HP:0003738)1.58897583
154Blue sclerae (HP:0000592)1.58606714
155Difficulty running (HP:0009046)1.57957096
156Hallux valgus (HP:0001822)1.57410004
157Bowel incontinence (HP:0002607)1.57101709
158Spina bifida occulta (HP:0003298)1.57094113
159Long palpebral fissure (HP:0000637)1.57093306
160Attention deficit hyperactivity disorder (HP:0007018)1.56622113
161Precocious puberty (HP:0000826)1.56248789
162Joint stiffness (HP:0001387)1.56146093
163Ventricular fibrillation (HP:0001663)1.55639048
164Acute lymphatic leukemia (HP:0006721)1.55088360
165Volvulus (HP:0002580)1.54326086
166Dilatation of the ascending aorta (HP:0005111)1.53332287
167Broad phalanges of the hand (HP:0009768)1.53202285
168Turricephaly (HP:0000262)1.53170251
169Hypertriglyceridemia (HP:0002155)1.52858102
170Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.52524202
171Distal lower limb amyotrophy (HP:0008944)1.49309892
172Fibroma (HP:0010614)1.48668095
173Fibrous tissue neoplasm (HP:0012316)1.48184107
174Bundle branch block (HP:0011710)1.47741182
175Uterine leiomyosarcoma (HP:0002891)1.47428975
176Leiomyosarcoma (HP:0100243)1.47428975

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K3.69486089
2TRIB33.57624422
3PRPF4B3.32177577
4CDK123.16929355
5PKN23.03896394
6MAP3K102.98357502
7SMG12.83666185
8SIK22.77671809
9ALK2.38160911
10RIPK12.21459479
11CAMK1G2.02486557
12ICK1.84087095
13TYRO31.81080736
14BRD41.70889587
15RIPK41.67196682
16NEK21.66185186
17PTK61.65535825
18MAP2K31.62275404
19PDGFRA1.59229425
20TAOK11.54698728
21TTN1.54429928
22MAP3K91.52518067
23PNCK1.51801984
24CAMK1D1.49278220
25CDC42BPA1.49029914
26SIK11.48996506
27STK381.48835131
28BMX1.43347762
29CDC71.38235386
30PAK61.35875616
31PRKD31.35304891
32MTOR1.35277881
33CAMKK11.30381858
34MAP3K71.27879555
35TYK21.18540018
36MAP4K11.18453305
37NTRK31.16100979
38RPS6KB21.14039107
39PRKCH1.11392717
40KSR21.11262959
41MARK21.10921065
42NEK11.06313043
43DAPK21.05206567
44ZAP701.03643254
45NTRK21.01666708
46LRRK21.01369632
47IRAK31.00996068
48MAP3K111.00500850
49NME20.99474725
50PAK40.97419913
51PDGFRB0.96034632
52MAPK120.95920876
53DMPK0.95544913
54MAP3K10.93282579
55TBK10.93071412
56BLK0.91014939
57WNK10.90243699
58CDK60.89940095
59MAPK110.89920243
60PDPK10.89178066
61MARK10.88841753
62LATS10.88771237
63JAK30.87837301
64MAP3K140.87148574
65TNK20.86392091
66CDK40.85260889
67RET0.84885390
68MAP3K60.84516686
69ERN10.82534178
70DDR20.82225494
71SIK30.81401191
72CHEK10.81147553
73STK100.80818375
74PRKD20.78767326
75FGFR20.78667214
76PAK20.77630686
77TTK0.77332800
78NTRK10.76764257
79STK110.76678904
80FGFR10.75190156
81IRAK40.74522631
82RPS6KL10.73988583
83RPS6KC10.73988583
84LATS20.73652203
85SGK30.71677760
86SCYL20.70410940
87BTK0.70280936
88PTK20.68165715
89GRK60.68035591
90UHMK10.68031769
91* CDK20.67796502
92EPHA40.67403209
93CSK0.66155331
94CSNK1E0.65892225
95FGFR40.64970450
96PDK10.64686210
97MAP2K20.64593385
98TAOK20.64124083
99PRKDC0.63415862
100MAP3K30.62645105
101MAP3K80.62253709
102CAMK40.61897727
103ATR0.60166235
104HCK0.59872457
105MAPK150.59294936
106KSR10.59150617
107ARAF0.58933527
108PRKD10.58882889
109ERBB20.58704418
110HIPK20.58444708
111MAPK70.57826349
112MAP2K60.57216736
113MAP3K40.56237360
114MAP3K130.54237987
115MAPK100.54207522
116RPS6KA60.53171391
117FES0.53097536
118EPHB10.52827127
119* MAPK80.52401625
120FGFR30.52087232
121CSNK1D0.50377620
122ITK0.50056945
123DYRK1B0.49674581
124MAPK140.49468251
125ATM0.49226148
126* GSK3B0.48490771
127* CDK10.47109239
128CAMK10.46836748
129AKT20.45927836
130RPS6KA30.44333011
131MST1R0.41220056
132IKBKE0.41215746
133IRAK20.39985450
134JAK20.39932028
135LMTK20.39871381
136MAPK90.39516144
137CDK50.39400853
138RPS6KA20.38544702
139JAK10.37961020
140TESK10.33341364
141RPS6KA10.32937535
142MAPK40.32597390

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005112.59812315
2Lysine degradation_Homo sapiens_hsa003101.74069718
3mTOR signaling pathway_Homo sapiens_hsa041501.63879220
4Long-term potentiation_Homo sapiens_hsa047201.58304826
5Chronic myeloid leukemia_Homo sapiens_hsa052201.56746782
6mRNA surveillance pathway_Homo sapiens_hsa030151.51909410
7Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.49986124
8Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.49753103
9Type II diabetes mellitus_Homo sapiens_hsa049301.47917786
10Notch signaling pathway_Homo sapiens_hsa043301.47060571
11Osteoclast differentiation_Homo sapiens_hsa043801.41659209
12Thyroid hormone signaling pathway_Homo sapiens_hsa049191.39527117
13Aldosterone synthesis and secretion_Homo sapiens_hsa049251.38843625
14Prion diseases_Homo sapiens_hsa050201.38688484
15Non-small cell lung cancer_Homo sapiens_hsa052231.37257851
16Phosphatidylinositol signaling system_Homo sapiens_hsa040701.37242150
17Glioma_Homo sapiens_hsa052141.36172266
18Estrogen signaling pathway_Homo sapiens_hsa049151.33547637
19Gastric acid secretion_Homo sapiens_hsa049711.31249668
20Endometrial cancer_Homo sapiens_hsa052131.28030770
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.27107931
22Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.24140471
23Leishmaniasis_Homo sapiens_hsa051401.20989862
24Circadian entrainment_Homo sapiens_hsa047131.20579821
25Neurotrophin signaling pathway_Homo sapiens_hsa047221.20027491
26Nitrogen metabolism_Homo sapiens_hsa009101.18260478
27Proteoglycans in cancer_Homo sapiens_hsa052051.18192034
28Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.17175007
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.17047242
30Dorso-ventral axis formation_Homo sapiens_hsa043201.16714538
31Glutamatergic synapse_Homo sapiens_hsa047241.16582078
32Oxytocin signaling pathway_Homo sapiens_hsa049211.15153087
33Basal cell carcinoma_Homo sapiens_hsa052171.15120856
34VEGF signaling pathway_Homo sapiens_hsa043701.14638507
35GnRH signaling pathway_Homo sapiens_hsa049121.14515972
36Salivary secretion_Homo sapiens_hsa049701.13701322
37Colorectal cancer_Homo sapiens_hsa052101.12393756
38T cell receptor signaling pathway_Homo sapiens_hsa046601.11461025
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.11223776
40Olfactory transduction_Homo sapiens_hsa047401.10920292
41Glycosaminoglycan degradation_Homo sapiens_hsa005311.10182639
42MicroRNAs in cancer_Homo sapiens_hsa052061.08406243
43ErbB signaling pathway_Homo sapiens_hsa040121.08384514
44Phospholipase D signaling pathway_Homo sapiens_hsa040721.07190721
45Toll-like receptor signaling pathway_Homo sapiens_hsa046201.05760480
46Cyanoamino acid metabolism_Homo sapiens_hsa004601.03729723
47Toxoplasmosis_Homo sapiens_hsa051451.03426090
48Longevity regulating pathway - mammal_Homo sapiens_hsa042111.03075951
49B cell receptor signaling pathway_Homo sapiens_hsa046621.00707618
50Cholinergic synapse_Homo sapiens_hsa047251.00110919
51Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99284878
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.98522917
53Acute myeloid leukemia_Homo sapiens_hsa052210.97863403
54Oocyte meiosis_Homo sapiens_hsa041140.97421044
55Hippo signaling pathway_Homo sapiens_hsa043900.97003413
56Amphetamine addiction_Homo sapiens_hsa050310.96548778
57Dopaminergic synapse_Homo sapiens_hsa047280.96529935
58Insulin secretion_Homo sapiens_hsa049110.96356565
59Renal cell carcinoma_Homo sapiens_hsa052110.95299389
60Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.95101965
61Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.94257358
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.92856736
63Gap junction_Homo sapiens_hsa045400.91609321
64Dilated cardiomyopathy_Homo sapiens_hsa054140.91554417
65Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.91536809
66Hepatitis B_Homo sapiens_hsa051610.91419452
67Adherens junction_Homo sapiens_hsa045200.91046642
68Small cell lung cancer_Homo sapiens_hsa052220.90953723
69Hepatitis C_Homo sapiens_hsa051600.90808517
70Primary immunodeficiency_Homo sapiens_hsa053400.90633272
71Influenza A_Homo sapiens_hsa051640.90529477
72Melanogenesis_Homo sapiens_hsa049160.90090865
73Morphine addiction_Homo sapiens_hsa050320.89685279
74HTLV-I infection_Homo sapiens_hsa051660.89262332
75GABAergic synapse_Homo sapiens_hsa047270.89117208
76Adipocytokine signaling pathway_Homo sapiens_hsa049200.88993143
77cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88742433
78Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.88719735
79TNF signaling pathway_Homo sapiens_hsa046680.88460320
80Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.88026072
81* Spliceosome_Homo sapiens_hsa030400.87487241
82Choline metabolism in cancer_Homo sapiens_hsa052310.87260121
83Focal adhesion_Homo sapiens_hsa045100.86350489
84Long-term depression_Homo sapiens_hsa047300.85315423
85MAPK signaling pathway_Homo sapiens_hsa040100.84121852
86Rap1 signaling pathway_Homo sapiens_hsa040150.83916924
87Pancreatic cancer_Homo sapiens_hsa052120.83848862
88Amoebiasis_Homo sapiens_hsa051460.83140438
89Thyroid cancer_Homo sapiens_hsa052160.82925642
90AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82463283
91Bladder cancer_Homo sapiens_hsa052190.82319004
92Hedgehog signaling pathway_Homo sapiens_hsa043400.82236826
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.81793001
94Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81260346
95Tuberculosis_Homo sapiens_hsa051520.81178205
96Nicotine addiction_Homo sapiens_hsa050330.80873903
97cAMP signaling pathway_Homo sapiens_hsa040240.80609981
98AMPK signaling pathway_Homo sapiens_hsa041520.80244264
99Fructose and mannose metabolism_Homo sapiens_hsa000510.79959342
100Synaptic vesicle cycle_Homo sapiens_hsa047210.79900530
101Wnt signaling pathway_Homo sapiens_hsa043100.79576153
102Staphylococcus aureus infection_Homo sapiens_hsa051500.78641587
103Prostate cancer_Homo sapiens_hsa052150.78585351
104Insulin signaling pathway_Homo sapiens_hsa049100.78410530
105Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.77657539
106Insulin resistance_Homo sapiens_hsa049310.76930269
107Platelet activation_Homo sapiens_hsa046110.76616279
108Inositol phosphate metabolism_Homo sapiens_hsa005620.76565314
109Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.75539565
110Chemokine signaling pathway_Homo sapiens_hsa040620.75406947
111Apoptosis_Homo sapiens_hsa042100.75350575
112RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.75087863
113Axon guidance_Homo sapiens_hsa043600.74848815
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.74760914
115Cocaine addiction_Homo sapiens_hsa050300.74718768
116Renin secretion_Homo sapiens_hsa049240.74541578
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.73662253
118Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.72740931
119Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.72565861
120Tight junction_Homo sapiens_hsa045300.71733340
121Pancreatic secretion_Homo sapiens_hsa049720.71372795
122Prolactin signaling pathway_Homo sapiens_hsa049170.70859593
123Herpes simplex infection_Homo sapiens_hsa051680.70579290
124Endocytosis_Homo sapiens_hsa041440.70415639
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70178427
126FoxO signaling pathway_Homo sapiens_hsa040680.69159978
127Leukocyte transendothelial migration_Homo sapiens_hsa046700.69076356
128RNA transport_Homo sapiens_hsa030130.68309941
129HIF-1 signaling pathway_Homo sapiens_hsa040660.67333738
130Thyroid hormone synthesis_Homo sapiens_hsa049180.67049596
131Pertussis_Homo sapiens_hsa051330.65425137
132Viral myocarditis_Homo sapiens_hsa054160.64533544
133Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61640160
134Viral carcinogenesis_Homo sapiens_hsa052030.60434861
135Measles_Homo sapiens_hsa051620.59630573
136Glycerophospholipid metabolism_Homo sapiens_hsa005640.56250596
137Pentose phosphate pathway_Homo sapiens_hsa000300.55174977
138Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.53827501
139Glucagon signaling pathway_Homo sapiens_hsa049220.50286188
140Malaria_Homo sapiens_hsa051440.48435487

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