SNRPA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.26022186
2DNA strand elongation involved in DNA replication (GO:0006271)5.07410956
3DNA unwinding involved in DNA replication (GO:0006268)4.87454840
4DNA strand elongation (GO:0022616)4.83648890
5formation of translation preinitiation complex (GO:0001731)4.68907583
6telomere maintenance via semi-conservative replication (GO:0032201)4.67465694
7DNA replication initiation (GO:0006270)4.64544184
8ribosomal small subunit assembly (GO:0000028)4.61211046
9mitotic chromosome condensation (GO:0007076)4.53723975
10nucleobase biosynthetic process (GO:0046112)4.22185479
11heterochromatin organization (GO:0070828)4.22169478
12telomere maintenance via recombination (GO:0000722)4.05947896
13maturation of SSU-rRNA (GO:0030490)4.00785879
14DNA replication checkpoint (GO:0000076)3.99648934
15purine nucleobase biosynthetic process (GO:0009113)3.93111097
16viral transcription (GO:0019083)3.92516510
17mitotic recombination (GO:0006312)3.92258137
18IMP biosynthetic process (GO:0006188)3.90492375
19regulation of translational fidelity (GO:0006450)3.87076098
20protein localization to kinetochore (GO:0034501)3.82903805
21translational termination (GO:0006415)3.82713372
22ribosome biogenesis (GO:0042254)3.79953684
23folic acid-containing compound biosynthetic process (GO:0009396)3.77005396
24telomere maintenance via telomere lengthening (GO:0010833)3.74783620
25mitotic nuclear envelope disassembly (GO:0007077)3.71616833
26translational elongation (GO:0006414)3.66969209
27nuclear pore complex assembly (GO:0051292)3.62165926
28translational initiation (GO:0006413)3.59991666
29histone arginine methylation (GO:0034969)3.58835116
30sister chromatid segregation (GO:0000819)3.58658685
31proline biosynthetic process (GO:0006561)3.58032970
32ribonucleoprotein complex biogenesis (GO:0022613)3.56430812
33mitotic metaphase plate congression (GO:0007080)3.55141627
34nucleotide-excision repair, DNA gap filling (GO:0006297)3.53671120
35spliceosomal snRNP assembly (GO:0000387)3.49935851
36establishment of viral latency (GO:0019043)3.49923006
37DNA replication-dependent nucleosome organization (GO:0034723)3.46672920
38DNA replication-dependent nucleosome assembly (GO:0006335)3.46672920
39regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.44239033
40macromolecular complex disassembly (GO:0032984)3.42105722
41DNA topological change (GO:0006265)3.41097209
42L-serine metabolic process (GO:0006563)3.40399880
43nuclear envelope disassembly (GO:0051081)3.39684170
44membrane disassembly (GO:0030397)3.39684170
45IMP metabolic process (GO:0046040)3.38989121
46protein localization to chromosome, centromeric region (GO:0071459)3.37957181
47ribosomal small subunit biogenesis (GO:0042274)3.37435637
48ribosome assembly (GO:0042255)3.37262668
49ribosomal large subunit biogenesis (GO:0042273)3.37190191
50negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.36802055
51nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.36389288
52establishment of integrated proviral latency (GO:0075713)3.36034961
53SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.29797981
54chromatin assembly (GO:0031497)3.29453441
55negative regulation of mRNA metabolic process (GO:1903312)3.28834985
56CENP-A containing nucleosome assembly (GO:0034080)3.27761977
57nucleosome disassembly (GO:0006337)3.26170835
58protein-DNA complex disassembly (GO:0032986)3.26170835
59viral mRNA export from host cell nucleus (GO:0046784)3.25483617
60chromatin remodeling at centromere (GO:0031055)3.25411410
61rRNA processing (GO:0006364)3.24948141
62peptidyl-arginine methylation (GO:0018216)3.23072438
63peptidyl-arginine N-methylation (GO:0035246)3.23072438
64negative regulation of RNA splicing (GO:0033119)3.22567803
65pseudouridine synthesis (GO:0001522)3.22358557
66deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.21146857
67spliceosomal tri-snRNP complex assembly (GO:0000244)3.21109624
68metaphase plate congression (GO:0051310)3.17777293
69nucleobase-containing small molecule interconversion (GO:0015949)3.17612640
70protein targeting to ER (GO:0045047)3.17044786
71cotranslational protein targeting to membrane (GO:0006613)3.16839171
72DNA replication-independent nucleosome assembly (GO:0006336)3.16415146
73DNA replication-independent nucleosome organization (GO:0034724)3.16415146
74transcription-coupled nucleotide-excision repair (GO:0006283)3.15944427
75DNA duplex unwinding (GO:0032508)3.13685377
76rRNA metabolic process (GO:0016072)3.13521182
77somatic hypermutation of immunoglobulin genes (GO:0016446)3.12136315
78somatic diversification of immune receptors via somatic mutation (GO:0002566)3.12136315
79DNA geometric change (GO:0032392)3.11919966
80proteasome assembly (GO:0043248)3.11441628
81negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.10103543
82regulation of mammary gland epithelial cell proliferation (GO:0033599)3.09886451
83pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.09084339
84anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.08069969
85mitotic sister chromatid segregation (GO:0000070)3.07486668
86histone H2A acetylation (GO:0043968)3.06643703
87pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.05289757
88rRNA transcription (GO:0009303)3.05253778
89viral life cycle (GO:0019058)3.04296136
90kinetochore organization (GO:0051383)3.03879876
91cellular protein complex disassembly (GO:0043624)3.03836360
92spliceosomal complex assembly (GO:0000245)3.03017916
93regulation of nuclear cell cycle DNA replication (GO:0033262)3.02999100
94regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.01041445
95protein complex localization (GO:0031503)2.99964671
96* RNA splicing, via transesterification reactions (GO:0000375)2.99845001
97* mRNA splicing, via spliceosome (GO:0000398)2.99608542
98* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.99608542
99base-excision repair (GO:0006284)2.98174518
100establishment of protein localization to endoplasmic reticulum (GO:0072599)2.97742270
101kinetochore assembly (GO:0051382)2.97273006
102protein localization to endoplasmic reticulum (GO:0070972)2.96318899
103chromosome condensation (GO:0030261)2.94627312
104chromatin assembly or disassembly (GO:0006333)2.94576767
105positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.94195702
106nuclear pore organization (GO:0006999)2.93741941
107protein complex disassembly (GO:0043241)2.92227193
108peptidyl-arginine omega-N-methylation (GO:0035247)2.92142485
109establishment of chromosome localization (GO:0051303)2.91449356
110G1/S transition of mitotic cell cycle (GO:0000082)2.89934914
111cell cycle G1/S phase transition (GO:0044843)2.89934914
112translation (GO:0006412)2.89450881
113pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.89103302
114regulation of spindle organization (GO:0090224)2.88253412
115negative regulation of chromosome segregation (GO:0051985)2.86942149
116mRNA catabolic process (GO:0006402)2.86140226
117termination of RNA polymerase II transcription (GO:0006369)2.85984806
118rRNA modification (GO:0000154)2.85013240
119negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.84835095
120negative regulation of ligase activity (GO:0051352)2.84835095
121telomere organization (GO:0032200)2.84340637
122regulation of mitochondrial translation (GO:0070129)2.84083201
123telomere maintenance (GO:0000723)2.83710790
124postreplication repair (GO:0006301)2.83195785
125pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.83082978
126DNA ligation (GO:0006266)2.82756947
127nuclear-transcribed mRNA catabolic process (GO:0000956)2.82694282
128negative regulation of mRNA processing (GO:0050686)2.82528824
129RNA catabolic process (GO:0006401)2.82195543
130negative regulation of mitotic sister chromatid separation (GO:2000816)2.81698838
131negative regulation of mitotic sister chromatid segregation (GO:0033048)2.81698838
132negative regulation of sister chromatid segregation (GO:0033046)2.81698838
133protein targeting to membrane (GO:0006612)2.79213881
134protein maturation by protein folding (GO:0022417)2.79190325
135pentose metabolic process (GO:0019321)2.77802499
136DNA conformation change (GO:0071103)2.77206506
137regulation of translational termination (GO:0006449)2.76424042
138oxidative phosphorylation (GO:0006119)2.75899165
139nuclear envelope reassembly (GO:0031468)2.75062539
140mitotic nuclear envelope reassembly (GO:0007084)2.75062539

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.74574491
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.25156554
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.01913342
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.34957926
5* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.11065045
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.93475066
7* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88980329
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.81888403
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.80561869
10* EST1_17652178_ChIP-ChIP_JURKAT_Human2.76804096
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.74598891
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.71387277
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.69731358
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.55780528
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.52190029
16XRN2_22483619_ChIP-Seq_HELA_Human2.42752094
17* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.38043627
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.35354974
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.29942258
20MYC_22102868_ChIP-Seq_BL_Human2.09329575
21EGR1_19374776_ChIP-ChIP_THP-1_Human2.04356625
22E2F1_18555785_ChIP-Seq_MESCs_Mouse2.02262384
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.01501405
24VDR_23849224_ChIP-Seq_CD4+_Human2.00943091
25* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.99565313
26GABP_19822575_ChIP-Seq_HepG2_Human1.89426168
27* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.88495770
28FOXP3_21729870_ChIP-Seq_TREG_Human1.86092646
29DCP1A_22483619_ChIP-Seq_HELA_Human1.85597390
30CIITA_25753668_ChIP-Seq_RAJI_Human1.84075928
31* ELF1_17652178_ChIP-ChIP_JURKAT_Human1.81501371
32* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80747053
33E2F1_21310950_ChIP-Seq_MCF-7_Human1.80528644
34AR_21909140_ChIP-Seq_LNCAP_Human1.79914710
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.78317033
36TTF2_22483619_ChIP-Seq_HELA_Human1.77904432
37NANOG_18555785_ChIP-Seq_MESCs_Mouse1.76872466
38* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.73317227
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.73296723
40TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.73212732
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68200496
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.64945740
43* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.62898503
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61804203
45* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.61204548
46* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.57751720
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48333312
48ZNF263_19887448_ChIP-Seq_K562_Human1.47914103
49POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.46121339
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.44917627
51KDM5A_27292631_Chip-Seq_BREAST_Human1.43156852
52VDR_21846776_ChIP-Seq_THP-1_Human1.41321496
53PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.40257670
54FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.35869293
55SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.35338949
56LXR_22292898_ChIP-Seq_THP-1_Human1.34909695
57ELK3_25401928_ChIP-Seq_HUVEC_Human1.34505567
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33561978
59FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.32819611
60POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32760385
61STAT3_1855785_ChIP-Seq_MESCs_Mouse1.32622327
62TP63_19390658_ChIP-ChIP_HaCaT_Human1.32402853
63SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.31876257
64* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.31009161
65* SRF_21415370_ChIP-Seq_HL-1_Mouse1.30279538
66* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.27855080
67ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.27375798
68KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.25844894
69ELK1_19687146_ChIP-ChIP_HELA_Human1.24384869
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.24307952
71DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.23388828
72SOX2_18555785_ChIP-Seq_MESCs_Mouse1.21194166
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20277169
74* TET1_21451524_ChIP-Seq_MESCs_Mouse1.17878275
75NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.17522156
76KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.16910352
77KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.16728321
78* TFEB_21752829_ChIP-Seq_HELA_Human1.15616894
79SRY_22984422_ChIP-ChIP_TESTIS_Rat1.15452182
80TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13660659
81E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11064017
82* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.09346913
83ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.08367084
84RACK7_27058665_Chip-Seq_MCF-7_Human1.08350160
85NCOR1_26117541_ChIP-Seq_K562_Human1.08015985
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.06680807
87P68_20966046_ChIP-Seq_HELA_Human1.06655774
88RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05685921
89MAF_26560356_Chip-Seq_TH1_Human1.03218956
90PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.02356382
91MAF_26560356_Chip-Seq_TH2_Human1.01155889
92DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00251169
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.99604047
94MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.99481554
95FOXP1_21924763_ChIP-Seq_HESCs_Human0.99137450
96CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98994455
97* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.98875365
98ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97379818
99ELF1_20517297_ChIP-Seq_JURKAT_Human0.97038125
100CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.96019410
101UTX_26944678_Chip-Seq_JUKART_Human0.95861399
102CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.95724357
103* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.95650945
104CTCF_18555785_ChIP-Seq_MESCs_Mouse0.95190149
105TCF3_18692474_ChIP-Seq_MEFs_Mouse0.93362805
106NOTCH1_21737748_ChIP-Seq_TLL_Human0.93290367
107OCT4_18692474_ChIP-Seq_MEFs_Mouse0.92332065
108TCF7_22412390_ChIP-Seq_EML_Mouse0.91580776
109SA1_27219007_Chip-Seq_ERYTHROID_Human0.91108584
110TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90641379
111* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.89920176
112SPI1_23547873_ChIP-Seq_NB4_Human0.89301400
113* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.88953723
114NANOG_21062744_ChIP-ChIP_HESCs_Human0.88431654
115* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86496242
116SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85408110
117ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.84697972
118HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.82049465
119E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.81726403
120NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.81533248
121MYC_18940864_ChIP-ChIP_HL60_Human0.80718646

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.20045249
2MP0004957_abnormal_blastocyst_morpholog4.30055303
3MP0010094_abnormal_chromosome_stability4.28703752
4MP0003111_abnormal_nucleus_morphology4.28495239
5MP0003077_abnormal_cell_cycle3.82553510
6MP0008057_abnormal_DNA_replication3.41945692
7MP0008058_abnormal_DNA_repair3.31454067
8MP0008007_abnormal_cellular_replicative3.23591150
9MP0002396_abnormal_hematopoietic_system2.55260556
10MP0008932_abnormal_embryonic_tissue2.53347465
11MP0003123_paternal_imprinting2.47539625
12MP0001730_embryonic_growth_arrest2.36162271
13MP0010352_gastrointestinal_tract_polyps2.33825136
14MP0000350_abnormal_cell_proliferation2.27922867
15MP0010030_abnormal_orbit_morphology2.17662505
16MP0003786_premature_aging2.09372259
17MP0005451_abnormal_body_composition2.00074660
18MP0002877_abnormal_melanocyte_morpholog1.89524620
19MP0004185_abnormal_adipocyte_glucose1.84855651
20MP0009379_abnormal_foot_pigmentation1.83329383
21MP0000490_abnormal_crypts_of1.79858949
22MP0001697_abnormal_embryo_size1.76702832
23MP0001672_abnormal_embryogenesis/_devel1.75783185
24MP0005380_embryogenesis_phenotype1.75783185
25MP0002080_prenatal_lethality1.66165282
26MP0008877_abnormal_DNA_methylation1.65837069
27MP0003984_embryonic_growth_retardation1.64568514
28MP0002088_abnormal_embryonic_growth/wei1.60330222
29MP0002085_abnormal_embryonic_tissue1.60116079
30MP0002653_abnormal_ependyma_morphology1.59737142
31MP0005397_hematopoietic_system_phenotyp1.58890448
32MP0001545_abnormal_hematopoietic_system1.58890448
33MP0000313_abnormal_cell_death1.56347085
34MP0004808_abnormal_hematopoietic_stem1.53556995
35MP0004197_abnormal_fetal_growth/weight/1.51195830
36MP0010307_abnormal_tumor_latency1.48579223
37MP0002084_abnormal_developmental_patter1.47046045
38MP0002019_abnormal_tumor_incidence1.46427587
39MP0004858_abnormal_nervous_system1.43628608
40MP0005501_abnormal_skin_physiology1.42309546
41MP0003567_abnormal_fetal_cardiomyocyte1.42103433
42MP0002086_abnormal_extraembryonic_tissu1.40065011
43MP0004133_heterotaxia1.39922648
44MP0009333_abnormal_splenocyte_physiolog1.38542076
45MP0003806_abnormal_nucleotide_metabolis1.36379200
46MP0006054_spinal_hemorrhage1.34043514
47MP0001293_anophthalmia1.33949565
48MP0001346_abnormal_lacrimal_gland1.31032817
49MP0003121_genomic_imprinting1.30903301
50MP0002163_abnormal_gland_morphology1.28045150
51MP0006292_abnormal_olfactory_placode1.25193258
52MP0003763_abnormal_thymus_physiology1.20265666
53MP0003890_abnormal_embryonic-extraembry1.18700856
54MP0003119_abnormal_digestive_system1.17807615
55MP0001661_extended_life_span1.14666704
56MP0003315_abnormal_perineum_morphology1.12401786
57MP0000703_abnormal_thymus_morphology1.12181667
58MP0002796_impaired_skin_barrier1.09168294
59MP0002160_abnormal_reproductive_system1.08943966
60MP0002722_abnormal_immune_system1.05118795
61MP0002398_abnormal_bone_marrow1.03797418
62MP0002697_abnormal_eye_size1.03016143
63MP0000358_abnormal_cell_content/1.02783732
64MP0000689_abnormal_spleen_morphology1.00474655
65MP0002132_abnormal_respiratory_system0.98958102
66MP0003186_abnormal_redox_activity0.98140498
67MP0009672_abnormal_birth_weight0.98010182
68MP0005076_abnormal_cell_differentiation0.96532916
69MP0002210_abnormal_sex_determination0.96425889
70MP0009697_abnormal_copulation0.96118468
71MP0009278_abnormal_bone_marrow0.95806263
72MP0000537_abnormal_urethra_morphology0.95400267
73MP0008260_abnormal_autophagy0.95389049
74MP0009053_abnormal_anal_canal0.95104897
75MP0000858_altered_metastatic_potential0.90243968
76MP0003718_maternal_effect0.89378740
77MP0008789_abnormal_olfactory_epithelium0.88545823
78MP0004233_abnormal_muscle_weight0.88002710
79MP0001145_abnormal_male_reproductive0.87914376
80MP0005023_abnormal_wound_healing0.84936135
81MP0002089_abnormal_postnatal_growth/wei0.84512500
82MP0005666_abnormal_adipose_tissue0.84098850
83MP0002111_abnormal_tail_morphology0.83693605
84MP0002429_abnormal_blood_cell0.81629793
85MP0000566_synostosis0.81047905
86MP0001881_abnormal_mammary_gland0.80746229
87MP0000049_abnormal_middle_ear0.79936128
88MP0005384_cellular_phenotype0.79426822
89MP0003705_abnormal_hypodermis_morpholog0.77715062
90MP0001915_intracranial_hemorrhage0.76843149
91MP0001727_abnormal_embryo_implantation0.76775873
92MP0000477_abnormal_intestine_morphology0.74672274
93MP0002009_preneoplasia0.74161067
94MP0003385_abnormal_body_wall0.73469594
95MP0001853_heart_inflammation0.73110228
96MP0005058_abnormal_lysosome_morphology0.72216738
97MP0005623_abnormal_meninges_morphology0.71345000
98MP0001119_abnormal_female_reproductive0.71343285
99MP0002938_white_spotting0.70669941
100MP0000653_abnormal_sex_gland0.70287508
101MP0005389_reproductive_system_phenotype0.70024170
102MP0009703_decreased_birth_body0.69884156
103MP0000678_abnormal_parathyroid_gland0.69014030
104MP0001873_stomach_inflammation0.68736617
105MP0003221_abnormal_cardiomyocyte_apopto0.68113157
106MP0002249_abnormal_larynx_morphology0.67416228
107MP0004264_abnormal_extraembryonic_tissu0.66957873
108MP0003566_abnormal_cell_adhesion0.66470756
109MP0005621_abnormal_cell_physiology0.66322013
110MP0001286_abnormal_eye_development0.65103055
111MP0002932_abnormal_joint_morphology0.64701673
112MP0001348_abnormal_lacrimal_gland0.64690623
113MP0006035_abnormal_mitochondrial_morpho0.64488458
114MP0003942_abnormal_urinary_system0.63353707
115MP0001849_ear_inflammation0.63342189
116MP0001929_abnormal_gametogenesis0.62524146
117MP0000716_abnormal_immune_system0.62503306
118MP0002092_abnormal_eye_morphology0.61584632
119MP0000428_abnormal_craniofacial_morphol0.61490013
120MP0006036_abnormal_mitochondrial_physio0.61413337
121MP0009931_abnormal_skin_appearance0.60635821
122MP0005075_abnormal_melanosome_morpholog0.58708210
123MP0005394_taste/olfaction_phenotype0.58539791
124MP0005499_abnormal_olfactory_system0.58539791
125MP0008770_decreased_survivor_rate0.56266774

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.46868008
2Abnormality of cells of the erythroid lineage (HP:0012130)4.21445308
3Abnormal number of erythroid precursors (HP:0012131)4.20457730
4Reticulocytopenia (HP:0001896)3.94441118
5Degeneration of anterior horn cells (HP:0002398)3.94410428
6Abnormality of the anterior horn cell (HP:0006802)3.94410428
7Selective tooth agenesis (HP:0001592)3.71637233
8Colon cancer (HP:0003003)3.71467175
9Oral leukoplakia (HP:0002745)3.68153946
10Breast hypoplasia (HP:0003187)3.60427227
11Microvesicular hepatic steatosis (HP:0001414)3.57087822
12Aplastic anemia (HP:0001915)3.54990285
13Ependymoma (HP:0002888)3.37068110
14Patellar aplasia (HP:0006443)3.36983853
15Medulloblastoma (HP:0002885)3.34730368
16Aplasia/Hypoplasia of the patella (HP:0006498)3.16161444
17Progressive muscle weakness (HP:0003323)3.11996286
18Cholecystitis (HP:0001082)2.97613575
19Abnormal gallbladder physiology (HP:0012438)2.97613575
20Broad distal phalanx of finger (HP:0009836)2.96138024
21Carpal bone hypoplasia (HP:0001498)2.95408957
22Rough bone trabeculation (HP:0100670)2.89503147
23Abnormal number of incisors (HP:0011064)2.82903006
24Microretrognathia (HP:0000308)2.75473744
25Trismus (HP:0000211)2.71557103
26Ragged-red muscle fibers (HP:0003200)2.68277002
27Meckel diverticulum (HP:0002245)2.66625875
28Agnosia (HP:0010524)2.66518824
29Multiple enchondromatosis (HP:0005701)2.65187277
30Abnormality of the ileum (HP:0001549)2.61555247
31Chromsome breakage (HP:0040012)2.61482739
32Pallor (HP:0000980)2.60934767
33Macrocytic anemia (HP:0001972)2.60786309
34Absent thumb (HP:0009777)2.57783239
35Neoplasm of the pancreas (HP:0002894)2.48905196
36Atrophy/Degeneration involving motor neurons (HP:0007373)2.48485938
37Cerebral hypomyelination (HP:0006808)2.48349546
3811 pairs of ribs (HP:0000878)2.48040494
39Chromosomal breakage induced by crosslinking agents (HP:0003221)2.44639293
40Truncus arteriosus (HP:0001660)2.43352938
41Premature graying of hair (HP:0002216)2.42594063
42Basal cell carcinoma (HP:0002671)2.40974365
43Thrombocytosis (HP:0001894)2.37664748
44Slender long bone (HP:0003100)2.35008729
45Rhabdomyosarcoma (HP:0002859)2.34936240
46Atresia of the external auditory canal (HP:0000413)2.34035622
47Abnormality of the preputium (HP:0100587)2.32631902
48Hypertensive crisis (HP:0100735)2.30155479
49Myelodysplasia (HP:0002863)2.25639541
50Abnormality of cochlea (HP:0000375)2.25588734
51Progressive external ophthalmoplegia (HP:0000590)2.25077968
52Abnormality of glycolysis (HP:0004366)2.23674388
53Aplasia/Hypoplasia of the uvula (HP:0010293)2.22183981
54Aplasia/Hypoplasia of the sacrum (HP:0008517)2.21514309
55Tracheoesophageal fistula (HP:0002575)2.19303045
56Abnormality of chromosome stability (HP:0003220)2.19242489
57Type I transferrin isoform profile (HP:0003642)2.17713689
58Aplasia/Hypoplasia of the thymus (HP:0010515)2.16506142
59Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.15822410
60Optic nerve coloboma (HP:0000588)2.15374391
61Duodenal stenosis (HP:0100867)2.14666765
62Small intestinal stenosis (HP:0012848)2.14666765
63Bone marrow hypocellularity (HP:0005528)2.13167413
64Reticulocytosis (HP:0001923)2.12851034
65Increased nuchal translucency (HP:0010880)2.11310023
66Absent radius (HP:0003974)2.11307767
67Premature ovarian failure (HP:0008209)2.10849454
68Abnormality of the umbilical cord (HP:0010881)2.10154384
69Abnormal lung lobation (HP:0002101)2.08845441
70Insomnia (HP:0100785)2.08677655
71Spinal muscular atrophy (HP:0007269)2.08168641
72Missing ribs (HP:0000921)2.05837217
73Spastic diplegia (HP:0001264)2.01977819
74Cellular immunodeficiency (HP:0005374)2.01150866
75Deep palmar crease (HP:0006191)2.01046240
76Proximal placement of thumb (HP:0009623)2.00846834
77Overlapping toe (HP:0001845)1.99998566
78Abnormality of the astrocytes (HP:0100707)1.99562632
79Astrocytoma (HP:0009592)1.99562632
80Seborrheic dermatitis (HP:0001051)1.98560755
81Impulsivity (HP:0100710)1.98215781
82Cleft eyelid (HP:0000625)1.97792193
83Short 4th metacarpal (HP:0010044)1.97774211
84Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.97774211
85Preauricular skin tag (HP:0000384)1.96904605
86Aplasia involving forearm bones (HP:0009822)1.95904006
87Absent forearm bone (HP:0003953)1.95904006
88Deviation of the thumb (HP:0009603)1.95743692
89Abnormal trabecular bone morphology (HP:0100671)1.95691951
90Amaurosis fugax (HP:0100576)1.94622507
91Duplication of thumb phalanx (HP:0009942)1.94338825
92Neoplasm of striated muscle (HP:0009728)1.93613741
93Glioma (HP:0009733)1.92285677
94Abnormality of the fetal cardiovascular system (HP:0010948)1.91989462
95Abnormal umbilical cord blood vessels (HP:0011403)1.91989462
96Single umbilical artery (HP:0001195)1.91989462
97Supernumerary spleens (HP:0009799)1.91783209
98Long palpebral fissure (HP:0000637)1.90814067
99Rib fusion (HP:0000902)1.90479317
100Abdominal situs inversus (HP:0003363)1.89543133
101Abnormality of abdominal situs (HP:0011620)1.89543133
102Hyperthyroidism (HP:0000836)1.85862730
103Horseshoe kidney (HP:0000085)1.85069983
104Decreased activity of mitochondrial respiratory chain (HP:0008972)1.85041137
105Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.85041137
106Renal duplication (HP:0000075)1.84935079
107Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.84817303
108Absent epiphyses (HP:0010577)1.84817303
109Tongue fasciculations (HP:0001308)1.84664529
110Abnormality of the calcaneus (HP:0008364)1.84365560
111Testicular atrophy (HP:0000029)1.83883384
112Premature skin wrinkling (HP:0100678)1.83447174
113Skin tags (HP:0010609)1.83292145
114Sloping forehead (HP:0000340)1.82743331
115Triphalangeal thumb (HP:0001199)1.82728862
116Overriding aorta (HP:0002623)1.81475124
117Hyperacusis (HP:0010780)1.81180256
118Adenoma sebaceum (HP:0009720)1.81090507
119Angiofibromas (HP:0010615)1.81090507
120Neoplasm of the oral cavity (HP:0100649)1.80817692
121Abnormality of reticulocytes (HP:0004312)1.80775765
122Abnormality of the duodenum (HP:0002246)1.80607418
123Hypoplasia of the capital femoral epiphysis (HP:0003090)1.80082171
124Glossoptosis (HP:0000162)1.79584755
125Lymphoma (HP:0002665)1.78456191
126Achilles tendon contracture (HP:0001771)1.78431513
127Pancytopenia (HP:0001876)1.78046079
128Aplasia/Hypoplasia of the sternum (HP:0006714)1.77465176
129Squamous cell carcinoma (HP:0002860)1.76973609
130Neoplasm of the colon (HP:0100273)1.76761133
131Prominent metopic ridge (HP:0005487)1.76349415
132Increased serum pyruvate (HP:0003542)1.75937987
133Increased intramyocellular lipid droplets (HP:0012240)1.75752789
134Disproportionate tall stature (HP:0001519)1.75008601
135High anterior hairline (HP:0009890)1.73937099
136Pseudobulbar signs (HP:0002200)1.73184044
137Poikiloderma (HP:0001029)1.72611909
138Poor head control (HP:0002421)1.71618432
139Biconcave vertebral bodies (HP:0004586)1.71194951
140Myopathic facies (HP:0002058)1.71133027
141Partial duplication of thumb phalanx (HP:0009944)1.70862649
142Hypoplasia of the radius (HP:0002984)1.70168728
143Septate vagina (HP:0001153)1.70016186
144Abnormally folded helix (HP:0008544)1.68512259
145Increased muscle lipid content (HP:0009058)1.65394478
146Hypoparathyroidism (HP:0000829)1.64954101
147Orthostatic hypotension (HP:0001278)1.63930187
148Gout (HP:0001997)1.63151486
149Tetralogy of Fallot (HP:0001636)1.62754118
150Short middle phalanx of the 5th finger (HP:0004220)1.62707015
151Nonimmune hydrops fetalis (HP:0001790)1.62501906
152Centrally nucleated skeletal muscle fibers (HP:0003687)1.62200789
153Unilateral renal agenesis (HP:0000122)1.61493747
154Ulnar bowing (HP:0003031)1.61376775
155Abnormality of the tricuspid valve (HP:0001702)1.61310422
156Rectal prolapse (HP:0002035)1.61033445
157Cholelithiasis (HP:0001081)1.58310490
158Secondary amenorrhea (HP:0000869)1.56628128

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.47881827
2SMG14.31076109
3VRK24.13285878
4CDC73.80987278
5WEE13.65604061
6EIF2AK12.65081688
7TESK22.57428814
8NEK22.54755383
9NEK12.36686482
10SRPK12.10825757
11TSSK62.05548805
12CDK71.96894779
13PASK1.95620708
14EEF2K1.93552927
15STK161.89309077
16ACVR1B1.87339571
17TTK1.85932605
18PLK11.80120459
19MAP3K101.79373830
20DYRK31.78915708
21IRAK31.77926854
22NME21.77575573
23PLK41.73444707
24RPS6KB21.72404193
25VRK11.69127740
26ATR1.67215807
27PIM21.65776687
28PAK41.61509836
29CDK121.61347057
30RPS6KA41.59556656
31BRSK21.58936441
32SCYL21.57401394
33TAF11.53681208
34MKNK11.53013926
35AURKB1.50468309
36TESK11.49880565
37PRPF4B1.48108166
38TGFBR11.46730505
39KDR1.40331384
40EIF2AK31.38156529
41CDK41.34679191
42AURKA1.29081784
43MAP3K81.26823985
44BRSK11.26343154
45PBK1.24429288
46PLK31.23682775
47MAP3K111.20879685
48STK101.20291014
49CHEK21.20185563
50PKN21.15539260
51CHEK11.11178290
52ERN11.09234877
53TAOK21.07111150
54FLT31.05810232
55MAP4K11.03305084
56CDK81.02387955
57TLK11.01477466
58TRIB31.00146414
59EPHA20.99577236
60BCKDK0.99265222
61LRRK20.95623860
62ARAF0.94139397
63MKNK20.93829998
64SIK10.92793842
65MAPKAPK30.92321539
66STK40.88872456
67NME10.87159431
68PIM10.85297942
69CDK20.82313288
70CCNB10.82006516
71PAK10.81287669
72MAP2K30.77779361
73ILK0.76740632
74BRD40.70465243
75ATM0.69270654
76CLK10.68385388
77PRKCI0.68106175
78CSNK2A20.66144863
79CDK90.65839225
80CSNK2A10.64978795
81BMX0.63027510
82BTK0.62817716
83ALK0.60396889
84BRAF0.59225624
85FGFR40.59088836
86LIMK10.58110550
87AKT20.57319623
88DAPK30.54693318
89CDK11A0.54492411
90ZAK0.54013095
91CDK60.53827511
92DAPK10.53727219
93MTOR0.52114740
94CDK10.50974113
95GRK60.46315605
96CDK150.46087275
97ZAP700.45422934
98LATS20.44565724
99ICK0.40716554
100MAPKAPK50.40282057
101TAOK10.40087694
102CDK180.40022922
103DYRK20.39537481
104CDK140.39400006
105CDK190.38593407
106PTK60.37490435
107KSR20.36450318
108IRAK40.35395812
109MAPK110.34077611
110MATK0.32790369
111RAF10.32405385
112RPS6KA60.31675190
113RPS6KC10.31448000
114RPS6KL10.31448000
115MAPKAPK20.30500929
116CHUK0.28483116
117CSF1R0.28456011
118PAK20.28032773
119TEC0.27968869
120RPS6KA10.27849307
121EIF2AK20.27655655
122MAP2K20.26471160
123RPS6KA50.25354477

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.28072727
2Mismatch repair_Homo sapiens_hsa034304.42555267
3Ribosome_Homo sapiens_hsa030103.60287524
4Base excision repair_Homo sapiens_hsa034103.45412683
5* Spliceosome_Homo sapiens_hsa030403.36798365
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.35292583
7Proteasome_Homo sapiens_hsa030503.28651370
8RNA polymerase_Homo sapiens_hsa030203.09604119
9RNA transport_Homo sapiens_hsa030132.96851034
10Homologous recombination_Homo sapiens_hsa034402.94322165
11Nucleotide excision repair_Homo sapiens_hsa034202.83953541
12One carbon pool by folate_Homo sapiens_hsa006702.63882109
13Cell cycle_Homo sapiens_hsa041102.62979926
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.51826524
15Pyrimidine metabolism_Homo sapiens_hsa002402.48784347
16Fanconi anemia pathway_Homo sapiens_hsa034601.98050960
17RNA degradation_Homo sapiens_hsa030181.80162216
18Non-homologous end-joining_Homo sapiens_hsa034501.80064557
19mRNA surveillance pathway_Homo sapiens_hsa030151.63862633
20Basal transcription factors_Homo sapiens_hsa030221.59512062
21p53 signaling pathway_Homo sapiens_hsa041151.48942367
22Purine metabolism_Homo sapiens_hsa002301.25614285
23Epstein-Barr virus infection_Homo sapiens_hsa051691.19383151
24Biosynthesis of amino acids_Homo sapiens_hsa012301.11502226
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.08532016
26Sulfur relay system_Homo sapiens_hsa041221.08502233
27Cysteine and methionine metabolism_Homo sapiens_hsa002700.97578711
28Cyanoamino acid metabolism_Homo sapiens_hsa004600.96169883
29Folate biosynthesis_Homo sapiens_hsa007900.96057638
30Pentose phosphate pathway_Homo sapiens_hsa000300.94982826
31Herpes simplex infection_Homo sapiens_hsa051680.93962074
32Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88372026
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.86965295
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.86301537
35Vitamin B6 metabolism_Homo sapiens_hsa007500.85531885
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85404844
37Antigen processing and presentation_Homo sapiens_hsa046120.83810590
38Viral carcinogenesis_Homo sapiens_hsa052030.83170724
39HTLV-I infection_Homo sapiens_hsa051660.80877073
40Thyroid cancer_Homo sapiens_hsa052160.80668463
41Selenocompound metabolism_Homo sapiens_hsa004500.80605731
42Drug metabolism - other enzymes_Homo sapiens_hsa009830.78746656
43Pyruvate metabolism_Homo sapiens_hsa006200.78184455
44Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76282692
45Systemic lupus erythematosus_Homo sapiens_hsa053220.75103110
46Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.74311872
47Oocyte meiosis_Homo sapiens_hsa041140.72765326
48Pancreatic cancer_Homo sapiens_hsa052120.71414275
49Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70468165
50Carbon metabolism_Homo sapiens_hsa012000.67162630
51Legionellosis_Homo sapiens_hsa051340.66638962
52Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.65948367
53N-Glycan biosynthesis_Homo sapiens_hsa005100.61954467
54Oxidative phosphorylation_Homo sapiens_hsa001900.59315101
55Notch signaling pathway_Homo sapiens_hsa043300.55428349
56Basal cell carcinoma_Homo sapiens_hsa052170.54117023
57Lysine degradation_Homo sapiens_hsa003100.53915965
58Fatty acid elongation_Homo sapiens_hsa000620.53810660
59Galactose metabolism_Homo sapiens_hsa000520.53375563
60Protein export_Homo sapiens_hsa030600.53299180
61Small cell lung cancer_Homo sapiens_hsa052220.52794946
62Glutathione metabolism_Homo sapiens_hsa004800.51319608
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50680172
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49784287
65Fructose and mannose metabolism_Homo sapiens_hsa000510.49161712
66Apoptosis_Homo sapiens_hsa042100.48848364
67Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48303558
68Shigellosis_Homo sapiens_hsa051310.48259797
69Bladder cancer_Homo sapiens_hsa052190.48234575
70MicroRNAs in cancer_Homo sapiens_hsa052060.48171947
71Primary immunodeficiency_Homo sapiens_hsa053400.47728042
72Huntingtons disease_Homo sapiens_hsa050160.47345247
73Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46837767
74Hippo signaling pathway_Homo sapiens_hsa043900.46386551
75Colorectal cancer_Homo sapiens_hsa052100.44883148
76B cell receptor signaling pathway_Homo sapiens_hsa046620.42103035
77Other glycan degradation_Homo sapiens_hsa005110.41955645
78Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.41299537
79Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.41035408
80Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.40734647
81Chronic myeloid leukemia_Homo sapiens_hsa052200.40300522
82Acute myeloid leukemia_Homo sapiens_hsa052210.39340172
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36658166
84TGF-beta signaling pathway_Homo sapiens_hsa043500.36571500
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.35971845
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.35147487
87Hepatitis B_Homo sapiens_hsa051610.33923626
88Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.31623051
89Prostate cancer_Homo sapiens_hsa052150.31185004
90Measles_Homo sapiens_hsa051620.31116002
91Prion diseases_Homo sapiens_hsa050200.31000299
92HIF-1 signaling pathway_Homo sapiens_hsa040660.29590363
93VEGF signaling pathway_Homo sapiens_hsa043700.29006542
94Alzheimers disease_Homo sapiens_hsa050100.28866347
95Hedgehog signaling pathway_Homo sapiens_hsa043400.28501965
96Parkinsons disease_Homo sapiens_hsa050120.27284495
97Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.24786416
98Pathways in cancer_Homo sapiens_hsa052000.24669009
99Alcoholism_Homo sapiens_hsa050340.22614650
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22277890
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.22062410
102Influenza A_Homo sapiens_hsa051640.20735768
103NF-kappa B signaling pathway_Homo sapiens_hsa040640.20530974
104Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.18977683
105Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.18726241
106Adherens junction_Homo sapiens_hsa045200.18721103
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.17654117
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.16880954
109Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.16858802
110Viral myocarditis_Homo sapiens_hsa054160.16163102
111Metabolic pathways_Homo sapiens_hsa011000.15368106
112mTOR signaling pathway_Homo sapiens_hsa041500.15069020
113Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.13362992
114Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.12420591
115Renin-angiotensin system_Homo sapiens_hsa046140.11014561
116Non-small cell lung cancer_Homo sapiens_hsa052230.10928116
117Endometrial cancer_Homo sapiens_hsa052130.10169413
118Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.10035516
119Leishmaniasis_Homo sapiens_hsa051400.09771185
120Arginine and proline metabolism_Homo sapiens_hsa003300.09713200
121Wnt signaling pathway_Homo sapiens_hsa043100.08956562

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