SNRPB2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)6.00494794
2ribosomal small subunit biogenesis (GO:0042274)5.91908341
3translational termination (GO:0006415)5.87022153
4ribosomal small subunit assembly (GO:0000028)5.62642105
5maturation of SSU-rRNA (GO:0030490)5.39028627
6mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.31425414
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.04326629
8respiratory electron transport chain (GO:0022904)5.03892284
9cotranslational protein targeting to membrane (GO:0006613)5.01676325
10ribosomal large subunit biogenesis (GO:0042273)4.96692456
11translational elongation (GO:0006414)4.96116502
12protein targeting to ER (GO:0045047)4.96043839
13electron transport chain (GO:0022900)4.93348270
14translational initiation (GO:0006413)4.74166750
15establishment of protein localization to endoplasmic reticulum (GO:0072599)4.72804258
16protein localization to endoplasmic reticulum (GO:0070972)4.71394529
17nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.67514712
18cellular protein complex disassembly (GO:0043624)4.65878499
19viral life cycle (GO:0019058)4.57573293
20proteasome assembly (GO:0043248)4.49677240
21protein complex biogenesis (GO:0070271)4.34498917
22mitochondrial respiratory chain complex assembly (GO:0033108)4.25843470
23mitochondrial respiratory chain complex I assembly (GO:0032981)4.11759092
24NADH dehydrogenase complex assembly (GO:0010257)4.11759092
25mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.11759092
26protein complex disassembly (GO:0043241)4.05941846
27CENP-A containing nucleosome assembly (GO:0034080)4.03609747
28ribonucleoprotein complex biogenesis (GO:0022613)3.97181340
29translation (GO:0006412)3.96290079
30establishment of integrated proviral latency (GO:0075713)3.92592598
31chromatin remodeling at centromere (GO:0031055)3.91899876
32DNA strand elongation involved in DNA replication (GO:0006271)3.87189456
33macromolecular complex disassembly (GO:0032984)3.86709374
34termination of RNA polymerase III transcription (GO:0006386)3.80868573
35transcription elongation from RNA polymerase III promoter (GO:0006385)3.80868573
36DNA replication initiation (GO:0006270)3.75011435
37telomere maintenance via semi-conservative replication (GO:0032201)3.74704637
38rRNA processing (GO:0006364)3.72094691
39spliceosomal snRNP assembly (GO:0000387)3.70749879
40GTP biosynthetic process (GO:0006183)3.69114331
41negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.67068874
42DNA strand elongation (GO:0022616)3.67066981
43regulation of mitochondrial translation (GO:0070129)3.62800495
44formation of translation preinitiation complex (GO:0001731)3.62753499
45nuclear-transcribed mRNA catabolic process (GO:0000956)3.61014373
46DNA replication checkpoint (GO:0000076)3.60904741
47kinetochore organization (GO:0051383)3.60870459
48rRNA metabolic process (GO:0016072)3.58080678
49protein neddylation (GO:0045116)3.56412657
50mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.55850993
517-methylguanosine mRNA capping (GO:0006370)3.51203848
52spliceosomal complex assembly (GO:0000245)3.49222059
537-methylguanosine RNA capping (GO:0009452)3.47746584
54RNA capping (GO:0036260)3.47746584
55respiratory chain complex IV assembly (GO:0008535)3.47013592
56telomere maintenance via recombination (GO:0000722)3.45981945
57rRNA modification (GO:0000154)3.45385280
58anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.44585195
59regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.44198270
60positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.44134994
61UTP biosynthetic process (GO:0006228)3.43766171
62mRNA catabolic process (GO:0006402)3.43422145
63establishment of protein localization to mitochondrial membrane (GO:0090151)3.43181996
64DNA damage response, detection of DNA damage (GO:0042769)3.43133179
65exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.41112417
66negative regulation of ligase activity (GO:0051352)3.38680965
67negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.38680965
68establishment of viral latency (GO:0019043)3.38678170
69DNA replication-independent nucleosome assembly (GO:0006336)3.38670038
70DNA replication-independent nucleosome organization (GO:0034724)3.38670038
71protein targeting to mitochondrion (GO:0006626)3.37995313
72energy coupled proton transport, down electrochemical gradient (GO:0015985)3.37741934
73ATP synthesis coupled proton transport (GO:0015986)3.37741934
74kinetochore assembly (GO:0051382)3.36882791
75nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.34009058
76establishment of protein localization to mitochondrion (GO:0072655)3.29495535
77ATP biosynthetic process (GO:0006754)3.28781865
78inner mitochondrial membrane organization (GO:0007007)3.28093661
79mitotic recombination (GO:0006312)3.27239093
80hydrogen ion transmembrane transport (GO:1902600)3.26862745
81histone exchange (GO:0043486)3.26484131
82protein localization to mitochondrion (GO:0070585)3.26447950
83transcription-coupled nucleotide-excision repair (GO:0006283)3.25982234
84RNA catabolic process (GO:0006401)3.25976817
85viral mRNA export from host cell nucleus (GO:0046784)3.25082536
86cytochrome complex assembly (GO:0017004)3.25068600
87mitotic metaphase plate congression (GO:0007080)3.24454976
88protein targeting to membrane (GO:0006612)3.22912089
89regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.22851404
90regulation of mitotic spindle checkpoint (GO:1903504)3.22851404
91sequestering of actin monomers (GO:0042989)3.22096433
92cellular component biogenesis (GO:0044085)3.21030358
93DNA deamination (GO:0045006)3.20965576
94pseudouridine synthesis (GO:0001522)3.20776203
95DNA unwinding involved in DNA replication (GO:0006268)3.19681013
96attachment of spindle microtubules to kinetochore (GO:0008608)3.19265629
97DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.18274970
98maturation of 5.8S rRNA (GO:0000460)3.17600469
99nucleotide-excision repair, DNA gap filling (GO:0006297)3.15582282
100signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.12819824
101intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.12819824
102RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.12316623
103tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.12316623
104guanosine-containing compound biosynthetic process (GO:1901070)3.09817129
105signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.09434094
106signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.09434094
107signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.09434094
108transcription elongation from RNA polymerase I promoter (GO:0006362)3.08550925
109water-soluble vitamin biosynthetic process (GO:0042364)3.07710248
110purine nucleoside triphosphate biosynthetic process (GO:0009145)3.07368653
111purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.05654512
112signal transduction involved in DNA damage checkpoint (GO:0072422)3.05312746
113signal transduction involved in DNA integrity checkpoint (GO:0072401)3.05312746
114protein localization to kinetochore (GO:0034501)3.05209780
115DNA double-strand break processing (GO:0000729)3.05171097
116histone mRNA metabolic process (GO:0008334)3.04329272
117signal transduction involved in cell cycle checkpoint (GO:0072395)3.04128626
118regulation of cellular amino acid metabolic process (GO:0006521)3.04092379
119telomere maintenance via telomere lengthening (GO:0010833)3.03200871
120positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.00988688
121termination of RNA polymerase I transcription (GO:0006363)2.99224686
122ribosome assembly (GO:0042255)2.98643933
123pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.94829727
124antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.91981739
125chaperone-mediated protein transport (GO:0072321)2.91134954
126positive regulation of ligase activity (GO:0051351)2.89929303
127ribosome biogenesis (GO:0042254)2.85910346
128DNA replication-dependent nucleosome assembly (GO:0006335)2.85374054

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.86162867
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.63176306
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.27054888
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.19818733
5* GABP_17652178_ChIP-ChIP_JURKAT_Human3.87127399
6* EST1_17652178_ChIP-ChIP_JURKAT_Human3.84844394
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.59298331
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.34003145
9* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.29859824
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.19270319
11MYC_19079543_ChIP-ChIP_MESCs_Mouse3.15863646
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.14686521
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.08159692
14* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.06079890
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.96290230
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.95611062
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.93416328
18MYC_18358816_ChIP-ChIP_MESCs_Mouse2.91378255
19CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.87071697
20FOXM1_23109430_ChIP-Seq_U2OS_Human2.77899637
21* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.77271118
22HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.73349187
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.72991560
24* VDR_23849224_ChIP-Seq_CD4+_Human2.66663627
25XRN2_22483619_ChIP-Seq_HELA_Human2.52172103
26ELK1_19687146_ChIP-ChIP_HELA_Human2.42570766
27DCP1A_22483619_ChIP-Seq_HELA_Human2.38007737
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.30825876
29TTF2_22483619_ChIP-Seq_HELA_Human2.30555007
30* FOXP3_21729870_ChIP-Seq_TREG_Human2.12612051
31E2F1_18555785_ChIP-Seq_MESCs_Mouse2.08133384
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.08105154
33* ELF1_17652178_ChIP-ChIP_JURKAT_Human2.03277476
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.01266060
35THAP11_20581084_ChIP-Seq_MESCs_Mouse1.91505862
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.89947887
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79167067
38* GABP_19822575_ChIP-Seq_HepG2_Human1.76016777
39ZNF274_21170338_ChIP-Seq_K562_Hela1.75559238
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.73179929
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.69694084
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.67463150
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66419865
44AR_21909140_ChIP-Seq_LNCAP_Human1.65776156
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.65270426
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.63868373
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62695218
48VDR_22108803_ChIP-Seq_LS180_Human1.59228488
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55960363
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.55089470
51PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52834387
52MYC_18940864_ChIP-ChIP_HL60_Human1.49539073
53NANOG_18555785_ChIP-Seq_MESCs_Mouse1.49130269
54RBPJ_22232070_ChIP-Seq_NCS_Mouse1.48083392
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.47773637
56FLI1_27457419_Chip-Seq_LIVER_Mouse1.45984647
57KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.36095965
58TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35964261
59* ELK1_22589737_ChIP-Seq_MCF10A_Human1.34480335
60PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.31923228
61* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.25657751
62PADI4_21655091_ChIP-ChIP_MCF-7_Human1.25048207
63KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.23548639
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.23343851
65ZFX_18555785_ChIP-Seq_MESCs_Mouse1.22748161
66ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21737994
67FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.21105921
68CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.18318090
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.17382147
70PCGF2_27294783_Chip-Seq_ESCs_Mouse1.14069937
71IRF1_19129219_ChIP-ChIP_H3396_Human1.13694733
72POU5F1_16153702_ChIP-ChIP_HESCs_Human1.09241346
73TAF15_26573619_Chip-Seq_HEK293_Human1.07551591
74* HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.07223514
75KDM5A_27292631_Chip-Seq_BREAST_Human1.06765768
76SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.00978127
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.00853334
78SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.00565803
79CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99828412
80MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.99784064
81POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99777385
82P300_19829295_ChIP-Seq_ESCs_Human0.99720375
83TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99184530
84FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.97369220
85CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97249566
86CIITA_25753668_ChIP-Seq_RAJI_Human0.96827107
87E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96561457
88SALL1_21062744_ChIP-ChIP_HESCs_Human0.94820948
89CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.92624727
90DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.92109438
91IGF1R_20145208_ChIP-Seq_DFB_Human0.91374281
92* SOX17_20123909_ChIP-Seq_XEN_Mouse0.91315104
93ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90523958
94SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.90485973
95CTBP1_25329375_ChIP-Seq_LNCAP_Human0.89380846
96NOTCH1_21737748_ChIP-Seq_TLL_Human0.88622132
97SOX2_16153702_ChIP-ChIP_HESCs_Human0.87692666
98EWS_26573619_Chip-Seq_HEK293_Human0.85297978
99BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.84781715
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84060943
101SPI1_23547873_ChIP-Seq_NB4_Human0.83438006
102NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.83110345
103FUS_26573619_Chip-Seq_HEK293_Human0.82566285
104* TP53_22573176_ChIP-Seq_HFKS_Human0.80819401
105TFEB_21752829_ChIP-Seq_HELA_Human0.80302811
106POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.78404964
107PCGF2_27294783_Chip-Seq_NPCs_Mouse0.78250938
108TCF3_18692474_ChIP-Seq_MEFs_Mouse0.77613553
109FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.76368658
110RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.76054200
111GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75838691
112KLF4_18555785_ChIP-Seq_MESCs_Mouse0.73353798
113NFE2_27457419_Chip-Seq_LIVER_Mouse0.73289206
114NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.71854745
115SOX2_18692474_ChIP-Seq_MEFs_Mouse0.71434729
116NANOG_16153702_ChIP-ChIP_HESCs_Human0.69666077
117* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.68843588
118* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.67271860
119NANOG_21062744_ChIP-ChIP_HESCs_Human0.65876556
120DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.65785871
121SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.65672941
122* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.65161640
123TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.64260046

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.63450901
2MP0009379_abnormal_foot_pigmentation4.21613231
3MP0010094_abnormal_chromosome_stability3.77836611
4MP0004957_abnormal_blastocyst_morpholog3.77680270
5MP0008057_abnormal_DNA_replication3.66334039
6MP0003077_abnormal_cell_cycle3.15104634
7MP0003111_abnormal_nucleus_morphology3.14034873
8MP0008932_abnormal_embryonic_tissue2.96796497
9MP0008058_abnormal_DNA_repair2.67836821
10MP0003718_maternal_effect2.25312982
11MP0003806_abnormal_nucleotide_metabolis2.21707245
12MP0003136_yellow_coat_color2.16408224
13MP0003315_abnormal_perineum_morphology2.09292661
14MP0008007_abnormal_cellular_replicative1.98514847
15MP0003941_abnormal_skin_development1.93311086
16MP0006292_abnormal_olfactory_placode1.90654971
17MP0003786_premature_aging1.90059555
18MP0002102_abnormal_ear_morphology1.85952824
19MP0003123_paternal_imprinting1.82826155
20MP0001529_abnormal_vocalization1.70664157
21MP0008877_abnormal_DNA_methylation1.67643445
22MP0005084_abnormal_gallbladder_morpholo1.63633718
23MP0000350_abnormal_cell_proliferation1.56993728
24MP0009697_abnormal_copulation1.55299648
25MP0002938_white_spotting1.54527341
26MP0006035_abnormal_mitochondrial_morpho1.52221593
27MP0005408_hypopigmentation1.50259049
28MP0003938_abnormal_ear_development1.48216973
29MP0006036_abnormal_mitochondrial_physio1.46350535
30MP0001730_embryonic_growth_arrest1.46277053
31MP0002396_abnormal_hematopoietic_system1.42269217
32MP0004142_abnormal_muscle_tone1.40435628
33MP0000490_abnormal_crypts_of1.39178610
34MP0001188_hyperpigmentation1.35405888
35MP0009333_abnormal_splenocyte_physiolog1.34574518
36MP0000537_abnormal_urethra_morphology1.33748384
37MP0003937_abnormal_limbs/digits/tail_de1.29615633
38MP0000631_abnormal_neuroendocrine_gland1.29065607
39MP0003011_delayed_dark_adaptation1.28067894
40MP0002736_abnormal_nociception_after1.26519066
41MP0002163_abnormal_gland_morphology1.25767684
42MP0010030_abnormal_orbit_morphology1.24586591
43MP0005499_abnormal_olfactory_system1.24492034
44MP0005394_taste/olfaction_phenotype1.24492034
45MP0005253_abnormal_eye_physiology1.24350034
46MP0002210_abnormal_sex_determination1.20740951
47MP0003121_genomic_imprinting1.20193868
48MP0008995_early_reproductive_senescence1.18720618
49MP0002234_abnormal_pharynx_morphology1.18542946
50MP0002233_abnormal_nose_morphology1.17581296
51MP0002751_abnormal_autonomic_nervous1.17494061
52MP0004381_abnormal_hair_follicle1.16720317
53MP0002277_abnormal_respiratory_mucosa1.16292786
54MP0001697_abnormal_embryo_size1.16240643
55MP0005409_darkened_coat_color1.14845714
56MP0000372_irregular_coat_pigmentation1.14434108
57MP0003880_abnormal_central_pattern1.14028192
58MP0005174_abnormal_tail_pigmentation1.13992848
59MP0002697_abnormal_eye_size1.11118405
60MP0002132_abnormal_respiratory_system1.10273364
61MP0000313_abnormal_cell_death1.10070407
62MP0002095_abnormal_skin_pigmentation1.08819332
63MP0008789_abnormal_olfactory_epithelium1.07554745
64MP0002085_abnormal_embryonic_tissue1.06948127
65MP0000049_abnormal_middle_ear1.06467073
66MP0003119_abnormal_digestive_system1.06351344
67MP0001984_abnormal_olfaction1.05301763
68MP0002282_abnormal_trachea_morphology1.05049523
69MP0001293_anophthalmia1.04324925
70MP0005391_vision/eye_phenotype1.03963146
71MP0005075_abnormal_melanosome_morpholog1.00560080
72MP0001905_abnormal_dopamine_level1.00208549
73MP0003567_abnormal_fetal_cardiomyocyte0.99736806
74MP0001145_abnormal_male_reproductive0.98521648
75MP0003122_maternal_imprinting0.97610868
76MP0002638_abnormal_pupillary_reflex0.97330619
77MP0001286_abnormal_eye_development0.95378390
78MP0002009_preneoplasia0.95179526
79MP0005551_abnormal_eye_electrophysiolog0.94929367
80MP0002080_prenatal_lethality0.94027478
81MP0001929_abnormal_gametogenesis0.93949513
82MP0002019_abnormal_tumor_incidence0.93717620
83MP0005171_absent_coat_pigmentation0.92773547
84MP0002837_dystrophic_cardiac_calcinosis0.92622757
85MP0000653_abnormal_sex_gland0.92381046
86MP0001727_abnormal_embryo_implantation0.90729314
87MP0005380_embryogenesis_phenotype0.89277787
88MP0001672_abnormal_embryogenesis/_devel0.89277787
89MP0005195_abnormal_posterior_eye0.88777849
90MP0001485_abnormal_pinna_reflex0.88705438
91MP0003890_abnormal_embryonic-extraembry0.88189168
92MP0002160_abnormal_reproductive_system0.88077880
93MP0008872_abnormal_physiological_respon0.88012775
94MP0003186_abnormal_redox_activity0.86769632
95MP0000778_abnormal_nervous_system0.86685561
96MP0001324_abnormal_eye_pigmentation0.86423567
97MP0005389_reproductive_system_phenotype0.84333451
98MP0000647_abnormal_sebaceous_gland0.83332029
99MP0002084_abnormal_developmental_patter0.83072698
100MP0000015_abnormal_ear_pigmentation0.83012755
101MP0000566_synostosis0.81496837
102MP0004133_heterotaxia0.80772869
103MP0006072_abnormal_retinal_apoptosis0.79566831
104MP0001119_abnormal_female_reproductive0.79488715
105MP0000358_abnormal_cell_content/0.79313424
106MP0009250_abnormal_appendicular_skeleto0.78352580
107MP0003763_abnormal_thymus_physiology0.78075809
108MP0000703_abnormal_thymus_morphology0.77963534
109MP0002090_abnormal_vision0.76891979
110MP0004742_abnormal_vestibular_system0.74921793
111MP0002752_abnormal_somatic_nervous0.74178433
112MP0002398_abnormal_bone_marrow0.74141702
113MP0002177_abnormal_outer_ear0.73143176
114MP0005379_endocrine/exocrine_gland_phen0.72428813
115MP0005671_abnormal_response_to0.72101320
116MP0004808_abnormal_hematopoietic_stem0.71120152
117MP0003755_abnormal_palate_morphology0.70763956
118MP0008260_abnormal_autophagy0.70198085
119MP0003984_embryonic_growth_retardation0.69725622
120MP0002148_abnormal_hypersensitivity_rea0.69280029
121MP0002111_abnormal_tail_morphology0.69166459
122MP0002092_abnormal_eye_morphology0.68992642
123MP0002272_abnormal_nervous_system0.68984487
124MP0002088_abnormal_embryonic_growth/wei0.67441012
125MP0002722_abnormal_immune_system0.67357609
126MP0002653_abnormal_ependyma_morphology0.66035289
127MP0006276_abnormal_autonomic_nervous0.65660860
128MP0000465_gastrointestinal_hemorrhage0.65345923
129MP0004197_abnormal_fetal_growth/weight/0.65136302
130MP0001919_abnormal_reproductive_system0.62295608
131MP0003861_abnormal_nervous_system0.61867586
132MP0002429_abnormal_blood_cell0.60374281
133MP0003724_increased_susceptibility_to0.60138639
134MP0009785_altered_susceptibility_to0.59005626

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.60186564
2Reticulocytopenia (HP:0001896)5.16797345
3Abnormal number of erythroid precursors (HP:0012131)4.97675350
4Birth length less than 3rd percentile (HP:0003561)4.26367766
5Macrocytic anemia (HP:0001972)3.97339311
6Pallor (HP:0000980)3.73234411
7Increased hepatocellular lipid droplets (HP:0006565)3.66013670
8Breast hypoplasia (HP:0003187)3.60718405
9Cerebral edema (HP:0002181)3.45553647
10Acute necrotizing encephalopathy (HP:0006965)3.25060029
11Mitochondrial inheritance (HP:0001427)3.15304511
12Cerebral hypomyelination (HP:0006808)3.13315742
13Chromsome breakage (HP:0040012)3.11022881
14Chromosomal breakage induced by crosslinking agents (HP:0003221)3.01824210
15Septo-optic dysplasia (HP:0100842)2.97900524
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.96022372
17Lipid accumulation in hepatocytes (HP:0006561)2.91046699
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.85695540
19Oral leukoplakia (HP:0002745)2.85529701
203-Methylglutaconic aciduria (HP:0003535)2.85415299
21Exertional dyspnea (HP:0002875)2.78281246
22Methylmalonic acidemia (HP:0002912)2.75472666
23Aplastic anemia (HP:0001915)2.74413874
24Patellar aplasia (HP:0006443)2.73989501
25Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.73456967
26Decreased activity of mitochondrial respiratory chain (HP:0008972)2.73456967
27Renal Fanconi syndrome (HP:0001994)2.73009317
28Abnormal mitochondria in muscle tissue (HP:0008316)2.72007772
29Increased CSF lactate (HP:0002490)2.70995115
30Aplasia/Hypoplasia of the sacrum (HP:0008517)2.70488255
31Rough bone trabeculation (HP:0100670)2.67994525
32Progressive macrocephaly (HP:0004481)2.67503488
33Aplasia/Hypoplasia of the patella (HP:0006498)2.67345843
34Lactic acidosis (HP:0003128)2.66247709
35Hepatocellular necrosis (HP:0001404)2.60502401
36Abnormality of the preputium (HP:0100587)2.58762007
37Absent radius (HP:0003974)2.56932892
38Triphalangeal thumb (HP:0001199)2.51260594
39Colon cancer (HP:0003003)2.50084189
40Aplasia involving forearm bones (HP:0009822)2.48511126
41Absent forearm bone (HP:0003953)2.48511126
42Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.47303082
43Absent thumb (HP:0009777)2.43230924
44Meckel diverticulum (HP:0002245)2.42022721
45Abnormality of renal resorption (HP:0011038)2.40970680
46Stenosis of the external auditory canal (HP:0000402)2.37861952
47Abnormality of chromosome stability (HP:0003220)2.32003137
48Methylmalonic aciduria (HP:0012120)2.29740154
49Respiratory difficulties (HP:0002880)2.28667066
50Abnormality of the ileum (HP:0001549)2.28466106
51Increased muscle lipid content (HP:0009058)2.28065675
52Horseshoe kidney (HP:0000085)2.27676142
53Cleft eyelid (HP:0000625)2.27553485
54Secondary amenorrhea (HP:0000869)2.25912425
55Premature graying of hair (HP:0002216)2.25367389
56Increased serum lactate (HP:0002151)2.19160322
57Acute encephalopathy (HP:0006846)2.18194068
58Absent septum pellucidum (HP:0001331)2.17994895
59Carpal bone hypoplasia (HP:0001498)2.17359931
60Supernumerary spleens (HP:0009799)2.17342591
61Molar tooth sign on MRI (HP:0002419)2.17002123
62Abnormality of midbrain morphology (HP:0002418)2.17002123
63Duplicated collecting system (HP:0000081)2.16429173
64True hermaphroditism (HP:0010459)2.14403726
65Lethargy (HP:0001254)2.12560745
66Increased serum pyruvate (HP:0003542)2.11584382
67Abnormality of glycolysis (HP:0004366)2.11584382
68Aplasia/Hypoplasia of the uvula (HP:0010293)2.11503417
69Congenital, generalized hypertrichosis (HP:0004540)2.10397858
70Hyperglycinemia (HP:0002154)2.08821050
71Abnormal trabecular bone morphology (HP:0100671)2.08285554
72Abnormal lung lobation (HP:0002101)2.07470002
73Glossoptosis (HP:0000162)2.07382767
74Irregular epiphyses (HP:0010582)2.07244902
75Abnormality of methionine metabolism (HP:0010901)2.07160792
76Bilateral microphthalmos (HP:0007633)2.02527395
77Hypoplasia of the radius (HP:0002984)2.02039702
78Asplenia (HP:0001746)2.00178731
79Medial flaring of the eyebrow (HP:0010747)1.99124608
80Abnormality of serum amino acid levels (HP:0003112)1.97837484
81Adrenal hypoplasia (HP:0000835)1.97607370
82Parakeratosis (HP:0001036)1.96052675
83X-linked dominant inheritance (HP:0001423)1.95055007
84Increased intramyocellular lipid droplets (HP:0012240)1.94895405
85Glycosuria (HP:0003076)1.93102432
86Abnormality of urine glucose concentration (HP:0011016)1.93102432
87Bone marrow hypocellularity (HP:0005528)1.92946897
88Pendular nystagmus (HP:0012043)1.92601624
89Hyperphosphaturia (HP:0003109)1.92391605
90Small intestinal stenosis (HP:0012848)1.91857871
91Duodenal stenosis (HP:0100867)1.91857871
92Abnormal number of incisors (HP:0011064)1.91739034
93Hypoplasia of the capital femoral epiphysis (HP:0003090)1.90413836
94Exercise intolerance (HP:0003546)1.90340806
95Short thumb (HP:0009778)1.89797122
96Abnormality of the labia minora (HP:0012880)1.88842665
97Abnormality of alanine metabolism (HP:0010916)1.88735850
98Hyperalaninemia (HP:0003348)1.88735850
99Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.88735850
100Anophthalmia (HP:0000528)1.88594997
101Atresia of the external auditory canal (HP:0000413)1.87329997
102Amniotic constriction ring (HP:0009775)1.87071467
103Abnormality of placental membranes (HP:0011409)1.87071467
104Abnormal hemoglobin (HP:0011902)1.86915354
105Abnormality of aspartate family amino acid metabolism (HP:0010899)1.86521646
106Hepatic necrosis (HP:0002605)1.86260741
107Pancreatic cysts (HP:0001737)1.82956266
108Sclerocornea (HP:0000647)1.82362575
109Abnormality of the septum pellucidum (HP:0007375)1.81873561
110Sparse lateral eyebrow (HP:0005338)1.81661588
111Degeneration of anterior horn cells (HP:0002398)1.81484422
112Abnormality of the anterior horn cell (HP:0006802)1.81484422
113CNS demyelination (HP:0007305)1.80854250
114Myelodysplasia (HP:0002863)1.79912625
11511 pairs of ribs (HP:0000878)1.78716202
116Respiratory failure (HP:0002878)1.78699887
117Pancytopenia (HP:0001876)1.77994187
118Leukodystrophy (HP:0002415)1.77353805
119Type I transferrin isoform profile (HP:0003642)1.77265588
120Depressed nasal ridge (HP:0000457)1.76907081
121Aplasia/Hypoplasia of the spleen (HP:0010451)1.76802338
122Abnormality of the renal collecting system (HP:0004742)1.76756153
123Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.75152551
124Generalized aminoaciduria (HP:0002909)1.74591150
125Selective tooth agenesis (HP:0001592)1.74481617
126Nephronophthisis (HP:0000090)1.73873465
127Megaloblastic anemia (HP:0001889)1.73730279
128Premature ovarian failure (HP:0008209)1.73558249
129Optic nerve hypoplasia (HP:0000609)1.73143437
130CNS hypomyelination (HP:0003429)1.72510656
131Trismus (HP:0000211)1.72154912
132Microvesicular hepatic steatosis (HP:0001414)1.71112584
133Oligodactyly (hands) (HP:0001180)1.70687010
134Pancreatic fibrosis (HP:0100732)1.70536545
135Hypoplasia of the pons (HP:0012110)1.70010185
136Abnormality of the pons (HP:0007361)1.69419814
137Tracheoesophageal fistula (HP:0002575)1.69060828
138Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.68718995
139Optic disc pallor (HP:0000543)1.67618898
140Absent epiphyses (HP:0010577)1.67193450
141Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.67193450
142Hypothermia (HP:0002045)1.67150919

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.34953472
2VRK24.19284535
3WEE13.72182710
4NME23.47021798
5EIF2AK13.32775403
6STK163.14513954
7SRPK13.02407662
8VRK12.68016677
9CDC72.65561839
10TLK12.60334397
11TRIM282.54610937
12MKNK12.51538130
13WNK32.35254182
14PBK2.26594358
15MKNK22.21434787
16NEK12.03807111
17PLK42.00029981
18EIF2AK31.98770562
19TESK21.82217970
20NUAK11.75058903
21ACVR1B1.74893748
22TAF11.68420220
23MST41.67513281
24TSSK61.66629554
25PLK11.56480280
26PNCK1.55820135
27DYRK31.54533719
28CASK1.53444281
29TTK1.49601525
30PLK31.39204860
31STK391.38933499
32MAP4K21.36499683
33NEK21.35219609
34AURKA1.31867746
35AURKB1.30212401
36BCR1.29225187
37BRSK21.28627005
38DYRK21.28182390
39LIMK11.22206711
40CHEK21.20929675
41PIM21.18422644
42NME11.16761231
43CDK71.14016115
44EIF2AK21.08230365
45INSRR1.08115506
46CDK191.07258500
47CLK11.00752300
48SCYL20.99096699
49ATR0.92472531
50MAP3K40.92309747
51IRAK40.92200407
52BMPR1B0.90567205
53RPS6KB20.87173487
54PASK0.86759908
55MAP2K70.86639371
56YES10.83896116
57CCNB10.81118677
58RPS6KA40.80058491
59CSNK2A10.79822939
60CSNK1G20.79792304
61TGFBR10.79590391
62TNIK0.77888677
63GRK10.77151004
64CSNK2A20.76802595
65CHEK10.75238009
66WNK40.74706178
67TAOK30.74621069
68RPS6KA50.74086396
69STK40.73888401
70CSNK1G30.72349035
71OXSR10.72174261
72STK38L0.70857151
73MAP3K120.70197866
74BRAF0.68980248
75PAK10.68410775
76PDK20.64780053
77MUSK0.64065583
78CDK80.63412002
79MAP3K80.61747376
80PIM10.61562350
81ARAF0.61527895
82KDR0.60771660
83PRKCG0.58537197
84ABL20.58500089
85BRSK10.58261500
86MELK0.57427112
87BMPR20.56996522
88CDK30.56041848
89CSNK1E0.55297190
90CSNK1G10.54143167
91TEC0.54000455
92BCKDK0.53913797
93STK100.53470439
94STK30.53274986
95PINK10.52922419
96ATM0.52684179
97MAP3K110.52274289
98FGFR10.50392211
99MINK10.49962741
100EPHA20.49578320
101NLK0.47697683
102LRRK20.47586807
103ALK0.45486632
104CDK20.44803974
105ZAK0.44708500
106ERBB40.44676609
107TESK10.42885439
108CDK40.42637121
109ADRBK20.41630752
110SIK30.40923571
111MAPKAPK50.40549838
112PAK40.39999034
113CDK10.39820992
114TXK0.38321753
115IRAK20.38169127
116CDK140.37190381
117MAPK130.36617840
118PLK20.36584776
119PRKCI0.34923514
120GRK70.34302423
121ILK0.32827472
122EPHB20.31460687
123CDK11A0.30580897
124LYN0.30398689
125BTK0.30353265
126DAPK30.30174570
127CSNK1A10.30044959
128PRKACB0.30000941
129NEK90.29973733
130CSNK1A1L0.29507908
131DYRK1A0.29412234
132ERBB30.29219218
133STK240.29160962
134CDK180.26389508
135PAK30.26259930

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.36917914
2Proteasome_Homo sapiens_hsa030504.11212497
3DNA replication_Homo sapiens_hsa030303.84138585
4RNA polymerase_Homo sapiens_hsa030203.78109173
5Mismatch repair_Homo sapiens_hsa034303.25982697
6* Spliceosome_Homo sapiens_hsa030403.19963638
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.11767549
8Homologous recombination_Homo sapiens_hsa034402.61863836
9Nucleotide excision repair_Homo sapiens_hsa034202.48370928
10Pyrimidine metabolism_Homo sapiens_hsa002402.47386642
11RNA transport_Homo sapiens_hsa030132.44991715
12Oxidative phosphorylation_Homo sapiens_hsa001902.41960715
13Basal transcription factors_Homo sapiens_hsa030222.33087053
14Base excision repair_Homo sapiens_hsa034102.27822130
15Parkinsons disease_Homo sapiens_hsa050122.15489674
16Cell cycle_Homo sapiens_hsa041102.10704477
17Protein export_Homo sapiens_hsa030602.08070680
18Fanconi anemia pathway_Homo sapiens_hsa034602.04958515
19Non-homologous end-joining_Homo sapiens_hsa034501.98307323
20Huntingtons disease_Homo sapiens_hsa050161.89685105
21RNA degradation_Homo sapiens_hsa030181.77072027
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.54190756
23Alzheimers disease_Homo sapiens_hsa050101.41098688
24Purine metabolism_Homo sapiens_hsa002301.38305604
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.32606315
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.30367815
27One carbon pool by folate_Homo sapiens_hsa006701.30229741
28mRNA surveillance pathway_Homo sapiens_hsa030151.28441531
29Epstein-Barr virus infection_Homo sapiens_hsa051691.23106123
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.19120762
31p53 signaling pathway_Homo sapiens_hsa041151.19046547
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.16733221
33Systemic lupus erythematosus_Homo sapiens_hsa053221.06491781
34Propanoate metabolism_Homo sapiens_hsa006401.02339830
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.00619775
36Pyruvate metabolism_Homo sapiens_hsa006200.93406063
37Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.93402088
38Selenocompound metabolism_Homo sapiens_hsa004500.84029967
39Oocyte meiosis_Homo sapiens_hsa041140.75867411
40Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75110131
41Herpes simplex infection_Homo sapiens_hsa051680.73442306
42Graft-versus-host disease_Homo sapiens_hsa053320.71197050
43Folate biosynthesis_Homo sapiens_hsa007900.69707072
44Allograft rejection_Homo sapiens_hsa053300.69192489
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.67190032
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61094570
47Viral carcinogenesis_Homo sapiens_hsa052030.60860338
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60187488
49Collecting duct acid secretion_Homo sapiens_hsa049660.59451667
50Antigen processing and presentation_Homo sapiens_hsa046120.58113584
51Sulfur relay system_Homo sapiens_hsa041220.57898632
52Ether lipid metabolism_Homo sapiens_hsa005650.55954007
53Asthma_Homo sapiens_hsa053100.54488247
54Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53751508
55Glutathione metabolism_Homo sapiens_hsa004800.53386005
56Autoimmune thyroid disease_Homo sapiens_hsa053200.51802397
57Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51726106
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51687080
59Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50872397
60Peroxisome_Homo sapiens_hsa041460.50720426
61Arachidonic acid metabolism_Homo sapiens_hsa005900.50697040
62Butanoate metabolism_Homo sapiens_hsa006500.50482787
63Primary immunodeficiency_Homo sapiens_hsa053400.50086338
64Cardiac muscle contraction_Homo sapiens_hsa042600.48835321
65Alcoholism_Homo sapiens_hsa050340.46374707
66Nicotine addiction_Homo sapiens_hsa050330.45821079
67Sulfur metabolism_Homo sapiens_hsa009200.45262030
68Intestinal immune network for IgA production_Homo sapiens_hsa046720.44932157
69Maturity onset diabetes of the young_Homo sapiens_hsa049500.44793807
70SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44376643
71HTLV-I infection_Homo sapiens_hsa051660.44145164
72NOD-like receptor signaling pathway_Homo sapiens_hsa046210.44023213
73Vitamin digestion and absorption_Homo sapiens_hsa049770.43874062
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43081137
75Hematopoietic cell lineage_Homo sapiens_hsa046400.41797331
76Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41211125
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.40722995
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.40554480
79Chemical carcinogenesis_Homo sapiens_hsa052040.40185194
80TGF-beta signaling pathway_Homo sapiens_hsa043500.37518518
81Shigellosis_Homo sapiens_hsa051310.36580038
82Tryptophan metabolism_Homo sapiens_hsa003800.36453363
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35807186
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.34804501
85Vitamin B6 metabolism_Homo sapiens_hsa007500.34681407
86Linoleic acid metabolism_Homo sapiens_hsa005910.34637338
87Caffeine metabolism_Homo sapiens_hsa002320.33667402
88Nitrogen metabolism_Homo sapiens_hsa009100.33616945
89Sphingolipid metabolism_Homo sapiens_hsa006000.33278304
90Rheumatoid arthritis_Homo sapiens_hsa053230.33119803
91Legionellosis_Homo sapiens_hsa051340.33030751
92NF-kappa B signaling pathway_Homo sapiens_hsa040640.31958738
93Measles_Homo sapiens_hsa051620.31917247
94Metabolic pathways_Homo sapiens_hsa011000.31686906
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.31229212
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.31007348
97Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.30455531
98Hedgehog signaling pathway_Homo sapiens_hsa043400.30344155
99Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29755331
100Malaria_Homo sapiens_hsa051440.29753778
101Basal cell carcinoma_Homo sapiens_hsa052170.29701921
102MicroRNAs in cancer_Homo sapiens_hsa052060.28584019
103Steroid biosynthesis_Homo sapiens_hsa001000.27979724
104Carbon metabolism_Homo sapiens_hsa012000.27962698
105Primary bile acid biosynthesis_Homo sapiens_hsa001200.26975479
106Pentose phosphate pathway_Homo sapiens_hsa000300.26851648
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.25256075
108Retinol metabolism_Homo sapiens_hsa008300.25102541
109Type I diabetes mellitus_Homo sapiens_hsa049400.23085972
110Biosynthesis of amino acids_Homo sapiens_hsa012300.22749721
111Phagosome_Homo sapiens_hsa041450.22546360
112Regulation of autophagy_Homo sapiens_hsa041400.21809516
113Small cell lung cancer_Homo sapiens_hsa052220.20933541
114Apoptosis_Homo sapiens_hsa042100.20515645
1152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.20333359
116Hepatitis B_Homo sapiens_hsa051610.19744775
117Thyroid cancer_Homo sapiens_hsa052160.19673143
118Hippo signaling pathway_Homo sapiens_hsa043900.19543513
119RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.19132687
120Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.18507965
121Vibrio cholerae infection_Homo sapiens_hsa051100.17668825
122Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.17274018
123Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.16842144
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.16797246
125beta-Alanine metabolism_Homo sapiens_hsa004100.16649015
126Pathways in cancer_Homo sapiens_hsa052000.16362588
127Colorectal cancer_Homo sapiens_hsa052100.16119599
128Taste transduction_Homo sapiens_hsa047420.15428028
129Phototransduction_Homo sapiens_hsa047440.15381386
130Prostate cancer_Homo sapiens_hsa052150.14949617
131Fatty acid elongation_Homo sapiens_hsa000620.14498576
132Tyrosine metabolism_Homo sapiens_hsa003500.13757098
133alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.13040628
134Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.13034684
135Cysteine and methionine metabolism_Homo sapiens_hsa002700.12883417
136Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.12709067
137Wnt signaling pathway_Homo sapiens_hsa043100.12375316
138Steroid hormone biosynthesis_Homo sapiens_hsa001400.11774152
139N-Glycan biosynthesis_Homo sapiens_hsa005100.11592477
140Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.11192972

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