

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine deamination (GO:0009972) | 8.74573031 |
| 2 | cytidine metabolic process (GO:0046087) | 8.74573031 |
| 3 | cytidine catabolic process (GO:0006216) | 8.74573031 |
| 4 | DNA deamination (GO:0045006) | 8.64639540 |
| 5 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.81780394 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.75651125 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.30905072 |
| 8 | positive regulation of interleukin-8 secretion (GO:2000484) | 5.22652347 |
| 9 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 5.14135943 |
| 10 | cytolysis (GO:0019835) | 5.05265951 |
| 11 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.62680454 |
| 12 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 4.46671193 |
| 13 | eosinophil chemotaxis (GO:0048245) | 4.34679127 |
| 14 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.33926720 |
| 15 | negative regulation by host of viral transcription (GO:0043922) | 4.32890749 |
| 16 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.27769006 |
| 17 | DNA demethylation (GO:0080111) | 4.24339752 |
| 18 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.22745716 |
| 19 | positive regulation of interleukin-1 secretion (GO:0050716) | 4.20037902 |
| 20 | regulation of regulatory T cell differentiation (GO:0045589) | 4.14746694 |
| 21 | cellular response to interleukin-15 (GO:0071350) | 4.09780839 |
| 22 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.04804346 |
| 23 | regulation of interleukin-1 beta secretion (GO:0050706) | 4.03637621 |
| 24 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.02009663 |
| 25 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.02009663 |
| 26 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.95788923 |
| 27 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.93975333 |
| 28 | response to interleukin-15 (GO:0070672) | 3.93266397 |
| 29 | regulation of interleukin-8 secretion (GO:2000482) | 3.92181043 |
| 30 | negative regulation of T cell apoptotic process (GO:0070233) | 3.91962748 |
| 31 | eosinophil migration (GO:0072677) | 3.91798077 |
| 32 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.86028380 |
| 33 | termination of RNA polymerase III transcription (GO:0006386) | 3.86028380 |
| 34 | metallo-sulfur cluster assembly (GO:0031163) | 3.80347522 |
| 35 | iron-sulfur cluster assembly (GO:0016226) | 3.80347522 |
| 36 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.77748984 |
| 37 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.77665737 |
| 38 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.77665737 |
| 39 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.77665737 |
| 40 | actin nucleation (GO:0045010) | 3.72396668 |
| 41 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.70961591 |
| 42 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.68306988 |
| 43 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.68306988 |
| 44 | chaperone-mediated protein transport (GO:0072321) | 3.66131796 |
| 45 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.63200570 |
| 46 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.63200570 |
| 47 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.62987760 |
| 48 | proteasome assembly (GO:0043248) | 3.62715258 |
| 49 | DNA dealkylation (GO:0035510) | 3.60829096 |
| 50 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.60196385 |
| 51 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.60196385 |
| 52 | negative regulation of ligase activity (GO:0051352) | 3.56353044 |
| 53 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.56353044 |
| 54 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.54892713 |
| 55 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.54892713 |
| 56 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.54260855 |
| 57 | regulation of interleukin-1 secretion (GO:0050704) | 3.51868868 |
| 58 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.50889236 |
| 59 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.50156790 |
| 60 | positive regulation of interleukin-1 beta production (GO:0032731) | 3.43169813 |
| 61 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.41516881 |
| 62 | protein-cofactor linkage (GO:0018065) | 3.40884633 |
| 63 | positive regulation of cell killing (GO:0031343) | 3.39056840 |
| 64 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.35767062 |
| 65 | respiratory electron transport chain (GO:0022904) | 3.35589274 |
| 66 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.34016632 |
| 67 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.32662719 |
| 68 | rRNA modification (GO:0000154) | 3.30700494 |
| 69 | electron transport chain (GO:0022900) | 3.30429698 |
| 70 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.22759515 |
| 71 | negative regulation of metanephros development (GO:0072217) | 3.15259809 |
| 72 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.15250918 |
| 73 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.13235400 |
| 74 | macrophage chemotaxis (GO:0048246) | 3.13146907 |
| 75 | protein neddylation (GO:0045116) | 3.09425343 |
| 76 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.07254314 |
| 77 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.07013524 |
| 78 | positive regulation of cell cycle arrest (GO:0071158) | 3.04604149 |
| 79 | negative regulation of viral genome replication (GO:0045071) | 3.04590424 |
| 80 | protein complex biogenesis (GO:0070271) | 3.01421654 |
| 81 | ATP synthesis coupled proton transport (GO:0015986) | 3.00850340 |
| 82 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.00850340 |
| 83 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.96261411 |
| 84 | positive regulation of interleukin-1 production (GO:0032732) | 2.94962538 |
| 85 | positive regulation of interleukin-17 production (GO:0032740) | 2.93987013 |
| 86 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.93574109 |
| 87 | inner mitochondrial membrane organization (GO:0007007) | 2.93136680 |
| 88 | regulation of cell killing (GO:0031341) | 2.90234497 |
| 89 | positive thymic T cell selection (GO:0045059) | 2.88606277 |
| 90 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.87202296 |
| 91 | positive regulation of defense response to virus by host (GO:0002230) | 2.86567112 |
| 92 | negative regulation of viral transcription (GO:0032897) | 2.82515483 |
| 93 | positive regulation of ligase activity (GO:0051351) | 2.82418426 |
| 94 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.80819986 |
| 95 | myeloid dendritic cell activation (GO:0001773) | 2.80647366 |
| 96 | rRNA methylation (GO:0031167) | 2.80580394 |
| 97 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.80290383 |
| 98 | regulation of mitochondrial translation (GO:0070129) | 2.78301921 |
| 99 | regulation of cellular amine metabolic process (GO:0033238) | 2.78231321 |
| 100 | regulation of activation of Janus kinase activity (GO:0010533) | 2.74981829 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.13116652 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.31953997 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.21171179 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.19564236 |
| 5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.43256814 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.40810021 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.32014761 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.22150337 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.90170718 |
| 10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.80093674 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.65328422 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.64362934 |
| 13 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.56016227 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.36602930 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.27826390 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.14445604 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.07767815 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.06173442 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.04829127 |
| 20 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.03435425 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.98701235 |
| 22 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.92513023 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.88984380 |
| 24 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.84728952 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.77562716 |
| 26 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.77116440 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.74069007 |
| 28 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.73678191 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69065195 |
| 30 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.67809671 |
| 31 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.66568613 |
| 32 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.62352341 |
| 33 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59284146 |
| 34 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56403230 |
| 35 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.54185870 |
| 36 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.48347540 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.48334461 |
| 38 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.43633367 |
| 39 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.41525291 |
| 40 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.37794399 |
| 41 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.34550406 |
| 42 | MYB_26560356_Chip-Seq_TH2_Human | 1.34008179 |
| 43 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.24494176 |
| 44 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.24206321 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.23597762 |
| 46 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.23314860 |
| 47 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.21523268 |
| 48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.16757402 |
| 49 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.15085413 |
| 50 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.14322022 |
| 51 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.11472236 |
| 52 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.11006239 |
| 53 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.10837907 |
| 54 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.10468249 |
| 55 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.10436541 |
| 56 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.09478704 |
| 57 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.09312494 |
| 58 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08896373 |
| 59 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.08729283 |
| 60 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08037845 |
| 61 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.07770566 |
| 62 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.07283913 |
| 63 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.04691582 |
| 64 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.02910635 |
| 65 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02123109 |
| 66 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.01162848 |
| 67 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.00566038 |
| 68 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.00566038 |
| 69 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.00206593 |
| 70 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.99999926 |
| 71 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99820151 |
| 72 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.97941856 |
| 73 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.97298754 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 0.96863941 |
| 75 | GATA3_26560356_Chip-Seq_TH2_Human | 0.96712988 |
| 76 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.96678280 |
| 77 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.96185240 |
| 78 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.94118433 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.93010556 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.93010556 |
| 81 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.92930978 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.92394163 |
| 83 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.92318448 |
| 84 | P300_19829295_ChIP-Seq_ESCs_Human | 0.92035085 |
| 85 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.91696335 |
| 86 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.91278925 |
| 87 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91029019 |
| 88 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.90638168 |
| 89 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.90509573 |
| 90 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90480326 |
| 91 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88757079 |
| 92 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88192201 |
| 93 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87423283 |
| 94 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.86897203 |
| 95 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86354544 |
| 96 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.86161534 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.85551566 |
| 98 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.85527360 |
| 99 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.84503598 |
| 100 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.84253057 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.27512465 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.90511667 |
| 3 | MP0009785_altered_susceptibility_to | 3.83271207 |
| 4 | MP0001873_stomach_inflammation | 3.16625880 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 3.04450713 |
| 6 | MP0005377_hearing/vestibular/ear_phenot | 2.85558013 |
| 7 | MP0003878_abnormal_ear_physiology | 2.85558013 |
| 8 | MP0006082_CNS_inflammation | 2.74910858 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.43632002 |
| 10 | MP0003866_abnormal_defecation | 2.41243393 |
| 11 | MP0004782_abnormal_surfactant_physiolog | 2.40834369 |
| 12 | MP0010307_abnormal_tumor_latency | 2.33176438 |
| 13 | MP0002148_abnormal_hypersensitivity_rea | 2.29464744 |
| 14 | MP0003448_altered_tumor_morphology | 2.26209968 |
| 15 | MP0002138_abnormal_hepatobiliary_system | 2.10350529 |
| 16 | MP0006036_abnormal_mitochondrial_physio | 2.04250459 |
| 17 | MP0001800_abnormal_humoral_immune | 2.01515193 |
| 18 | MP0002876_abnormal_thyroid_physiology | 1.95493443 |
| 19 | MP0005387_immune_system_phenotype | 1.92165677 |
| 20 | MP0001790_abnormal_immune_system | 1.92165677 |
| 21 | MP0001958_emphysema | 1.87800149 |
| 22 | MP0003786_premature_aging | 1.83605282 |
| 23 | MP0006035_abnormal_mitochondrial_morpho | 1.81780362 |
| 24 | MP0010155_abnormal_intestine_physiology | 1.81222663 |
| 25 | MP0005310_abnormal_salivary_gland | 1.80695733 |
| 26 | MP0004145_abnormal_muscle_electrophysio | 1.75504189 |
| 27 | MP0002405_respiratory_system_inflammati | 1.69641866 |
| 28 | MP0002420_abnormal_adaptive_immunity | 1.64430685 |
| 29 | MP0002723_abnormal_immune_serum | 1.60922461 |
| 30 | MP0005025_abnormal_response_to | 1.60131691 |
| 31 | MP0001661_extended_life_span | 1.58889970 |
| 32 | MP0001819_abnormal_immune_cell | 1.56906826 |
| 33 | MP0004147_increased_porphyrin_level | 1.50998161 |
| 34 | MP0002006_tumorigenesis | 1.39983504 |
| 35 | MP0003763_abnormal_thymus_physiology | 1.37424880 |
| 36 | MP0001485_abnormal_pinna_reflex | 1.37217892 |
| 37 | MP0008875_abnormal_xenobiotic_pharmacok | 1.33634660 |
| 38 | MP0002166_altered_tumor_susceptibility | 1.31194051 |
| 39 | MP0002452_abnormal_antigen_presenting | 1.29714164 |
| 40 | MP0008877_abnormal_DNA_methylation | 1.28884396 |
| 41 | MP0001986_abnormal_taste_sensitivity | 1.24131258 |
| 42 | MP0000716_abnormal_immune_system | 1.23751041 |
| 43 | MP0005410_abnormal_fertilization | 1.21952731 |
| 44 | MP0003045_fibrosis | 1.17372779 |
| 45 | MP0003186_abnormal_redox_activity | 1.17363856 |
| 46 | MP0002822_catalepsy | 1.17064947 |
| 47 | MP0005075_abnormal_melanosome_morpholog | 1.15520696 |
| 48 | MP0002398_abnormal_bone_marrow | 1.15086490 |
| 49 | MP0001845_abnormal_inflammatory_respons | 1.14738702 |
| 50 | MP0002722_abnormal_immune_system | 1.14711099 |
| 51 | MP0000689_abnormal_spleen_morphology | 1.09722934 |
| 52 | MP0002429_abnormal_blood_cell | 1.03696274 |
| 53 | MP0003195_calcinosis | 1.02646190 |
| 54 | MP0002693_abnormal_pancreas_physiology | 1.02109605 |
| 55 | MP0002277_abnormal_respiratory_mucosa | 1.00838947 |
| 56 | MP0003137_abnormal_impulse_conducting | 1.00709021 |
| 57 | MP0001881_abnormal_mammary_gland | 0.99821389 |
| 58 | MP0008873_increased_physiological_sensi | 0.99566603 |
| 59 | MP0008469_abnormal_protein_level | 0.99196998 |
| 60 | MP0004142_abnormal_muscle_tone | 0.96311479 |
| 61 | MP0009765_abnormal_xenobiotic_induced | 0.96111193 |
| 62 | MP0003567_abnormal_fetal_cardiomyocyte | 0.95887511 |
| 63 | MP0002933_joint_inflammation | 0.93131442 |
| 64 | MP0005551_abnormal_eye_electrophysiolog | 0.92839049 |
| 65 | MP0001905_abnormal_dopamine_level | 0.92815528 |
| 66 | MP0006072_abnormal_retinal_apoptosis | 0.92683009 |
| 67 | MP0004957_abnormal_blastocyst_morpholog | 0.91258146 |
| 68 | MP0000703_abnormal_thymus_morphology | 0.90738891 |
| 69 | MP0005645_abnormal_hypothalamus_physiol | 0.88047215 |
| 70 | MP0008872_abnormal_physiological_respon | 0.87103979 |
| 71 | MP0006276_abnormal_autonomic_nervous | 0.85628660 |
| 72 | MP0002102_abnormal_ear_morphology | 0.85152568 |
| 73 | MP0001853_heart_inflammation | 0.85004743 |
| 74 | MP0002419_abnormal_innate_immunity | 0.84784278 |
| 75 | MP0009764_decreased_sensitivity_to | 0.84687938 |
| 76 | MP0004885_abnormal_endolymph | 0.84475866 |
| 77 | MP0005174_abnormal_tail_pigmentation | 0.82800040 |
| 78 | MP0005636_abnormal_mineral_homeostasis | 0.82688233 |
| 79 | MP0009763_increased_sensitivity_to | 0.81466166 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.81446930 |
| 81 | MP0002095_abnormal_skin_pigmentation | 0.80775113 |
| 82 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.79818119 |
| 83 | MP0009745_abnormal_behavioral_response | 0.76368654 |
| 84 | MP0000358_abnormal_cell_content/ | 0.75676662 |
| 85 | MP0008770_decreased_survivor_rate | 0.75635131 |
| 86 | MP0005319_abnormal_enzyme/_coenzyme | 0.75206350 |
| 87 | MP0001529_abnormal_vocalization | 0.74912803 |
| 88 | MP0004134_abnormal_chest_morphology | 0.74469907 |
| 89 | MP0002163_abnormal_gland_morphology | 0.72287914 |
| 90 | MP0005084_abnormal_gallbladder_morpholo | 0.69475188 |
| 91 | MP0003111_abnormal_nucleus_morphology | 0.68708587 |
| 92 | MP0003718_maternal_effect | 0.66398029 |
| 93 | MP0001984_abnormal_olfaction | 0.65579168 |
| 94 | MP0002019_abnormal_tumor_incidence | 0.63204455 |
| 95 | MP0001764_abnormal_homeostasis | 0.62776870 |
| 96 | MP0001119_abnormal_female_reproductive | 0.62600443 |
| 97 | MP0001919_abnormal_reproductive_system | 0.62190849 |
| 98 | MP0000569_abnormal_digit_pigmentation | 0.61122550 |
| 99 | MP0003011_delayed_dark_adaptation | 0.60779412 |
| 100 | MP0003936_abnormal_reproductive_system | 0.60502560 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 4.75034549 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.72281105 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.60116126 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.30798659 |
| 5 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.26447857 |
| 6 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.26447857 |
| 7 | Hypoproteinemia (HP:0003075) | 4.07039578 |
| 8 | Hepatocellular necrosis (HP:0001404) | 4.01657333 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.94510676 |
| 10 | Hepatic necrosis (HP:0002605) | 3.92979344 |
| 11 | Abnormal biliary tract physiology (HP:0012439) | 3.86604392 |
| 12 | Bile duct proliferation (HP:0001408) | 3.86604392 |
| 13 | Acute encephalopathy (HP:0006846) | 3.86071106 |
| 14 | Aplastic anemia (HP:0001915) | 3.86034981 |
| 15 | Increased intramyocellular lipid droplets (HP:0012240) | 3.85047331 |
| 16 | Increased CSF lactate (HP:0002490) | 3.81977297 |
| 17 | Cerebral edema (HP:0002181) | 3.67518519 |
| 18 | T lymphocytopenia (HP:0005403) | 3.44520717 |
| 19 | Pancreatic cysts (HP:0001737) | 3.42252199 |
| 20 | True hermaphroditism (HP:0010459) | 3.31233328 |
| 21 | Increased hepatocellular lipid droplets (HP:0006565) | 3.29684134 |
| 22 | Pancreatic fibrosis (HP:0100732) | 3.22303476 |
| 23 | Abnormality of T cell number (HP:0011839) | 3.20699698 |
| 24 | Zonular cataract (HP:0010920) | 3.17397256 |
| 25 | Renal Fanconi syndrome (HP:0001994) | 3.14232454 |
| 26 | Increased muscle lipid content (HP:0009058) | 3.05658321 |
| 27 | Increased serum lactate (HP:0002151) | 2.97664171 |
| 28 | Abnormality of midbrain morphology (HP:0002418) | 2.96532237 |
| 29 | Molar tooth sign on MRI (HP:0002419) | 2.96532237 |
| 30 | Lipid accumulation in hepatocytes (HP:0006561) | 2.84260550 |
| 31 | Generalized aminoaciduria (HP:0002909) | 2.84195224 |
| 32 | Abnormality of the prostate (HP:0008775) | 2.84031426 |
| 33 | Hemiplegia (HP:0002301) | 2.81629018 |
| 34 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.79561966 |
| 35 | Optic disc pallor (HP:0000543) | 2.69949144 |
| 36 | Lactic acidosis (HP:0003128) | 2.63271690 |
| 37 | Exercise intolerance (HP:0003546) | 2.61626190 |
| 38 | IgG deficiency (HP:0004315) | 2.60429106 |
| 39 | Exertional dyspnea (HP:0002875) | 2.51573792 |
| 40 | Increased IgM level (HP:0003496) | 2.48913839 |
| 41 | Abnormality of T cells (HP:0002843) | 2.39014132 |
| 42 | Abnormal albumin level (HP:0012116) | 2.37711752 |
| 43 | Hypoalbuminemia (HP:0003073) | 2.37711752 |
| 44 | Renal cortical cysts (HP:0000803) | 2.36726413 |
| 45 | Gastrointestinal infarctions (HP:0005244) | 2.28658062 |
| 46 | Leukodystrophy (HP:0002415) | 2.28237998 |
| 47 | Respiratory failure (HP:0002878) | 2.27033983 |
| 48 | Microvesicular hepatic steatosis (HP:0001414) | 2.23109362 |
| 49 | CNS demyelination (HP:0007305) | 2.20812588 |
| 50 | Palpitations (HP:0001962) | 2.19600777 |
| 51 | Hypoglycemic seizures (HP:0002173) | 2.17900993 |
| 52 | Hypothermia (HP:0002045) | 2.16133472 |
| 53 | Autoimmune hemolytic anemia (HP:0001890) | 2.13337114 |
| 54 | Encephalitis (HP:0002383) | 2.03538302 |
| 55 | Hemoptysis (HP:0002105) | 2.02795882 |
| 56 | Cerebral hypomyelination (HP:0006808) | 2.02254995 |
| 57 | Hypoglycemic coma (HP:0001325) | 2.00921676 |
| 58 | Amaurosis fugax (HP:0100576) | 2.00438362 |
| 59 | Abolished electroretinogram (ERG) (HP:0000550) | 1.99371728 |
| 60 | Sclerocornea (HP:0000647) | 1.99166023 |
| 61 | Emotional lability (HP:0000712) | 1.99003272 |
| 62 | Gangrene (HP:0100758) | 1.97442210 |
| 63 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.96571512 |
| 64 | Postaxial foot polydactyly (HP:0001830) | 1.95638338 |
| 65 | Cerebral hemorrhage (HP:0001342) | 1.94867302 |
| 66 | Cystic liver disease (HP:0006706) | 1.94750036 |
| 67 | Lethargy (HP:0001254) | 1.94613611 |
| 68 | Meningitis (HP:0001287) | 1.91936599 |
| 69 | Chronic diarrhea (HP:0002028) | 1.89078742 |
| 70 | Hyponatremia (HP:0002902) | 1.87326978 |
| 71 | Panhypogammaglobulinemia (HP:0003139) | 1.87128467 |
| 72 | Short tibia (HP:0005736) | 1.86309675 |
| 73 | Abnormality of DNA repair (HP:0003254) | 1.85983843 |
| 74 | Tetraplegia (HP:0002445) | 1.84245164 |
| 75 | Type I transferrin isoform profile (HP:0003642) | 1.84103257 |
| 76 | Thyroiditis (HP:0100646) | 1.83773042 |
| 77 | Stomatitis (HP:0010280) | 1.82135960 |
| 78 | Chest pain (HP:0100749) | 1.81848309 |
| 79 | Abnormality of renal resorption (HP:0011038) | 1.80386090 |
| 80 | Severe combined immunodeficiency (HP:0004430) | 1.79598046 |
| 81 | Hypoplasia of the thymus (HP:0000778) | 1.79242596 |
| 82 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.79193205 |
| 83 | Glycosuria (HP:0003076) | 1.79025760 |
| 84 | Abnormality of urine glucose concentration (HP:0011016) | 1.79025760 |
| 85 | Carpal bone hypoplasia (HP:0001498) | 1.77840683 |
| 86 | Type 2 muscle fiber atrophy (HP:0003554) | 1.75629489 |
| 87 | Spastic paraparesis (HP:0002313) | 1.73384915 |
| 88 | Pancytopenia (HP:0001876) | 1.72069456 |
| 89 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.70118215 |
| 90 | Joint swelling (HP:0001386) | 1.69778379 |
| 91 | Male pseudohermaphroditism (HP:0000037) | 1.69725136 |
| 92 | Ketosis (HP:0001946) | 1.69104833 |
| 93 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.69007919 |
| 94 | X-linked dominant inheritance (HP:0001423) | 1.68757118 |
| 95 | Constricted visual fields (HP:0001133) | 1.68119465 |
| 96 | Bifid tongue (HP:0010297) | 1.65881471 |
| 97 | Periodontitis (HP:0000704) | 1.61514220 |
| 98 | Nephronophthisis (HP:0000090) | 1.61136658 |
| 99 | Pendular nystagmus (HP:0012043) | 1.58836716 |
| 100 | Clitoromegaly (HP:0000057) | 1.57739340 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.73180625 |
| 2 | ZAK | 4.69677871 |
| 3 | BUB1 | 3.97679164 |
| 4 | EIF2AK3 | 3.82091608 |
| 5 | KDR | 3.51740238 |
| 6 | STK16 | 3.40127197 |
| 7 | MST4 | 3.38062887 |
| 8 | TRIM28 | 3.30274780 |
| 9 | BCKDK | 3.26487224 |
| 10 | ITK | 2.84396613 |
| 11 | EIF2AK1 | 2.44851799 |
| 12 | VRK2 | 2.33534844 |
| 13 | TLK1 | 2.13406355 |
| 14 | PIK3CA | 1.85642417 |
| 15 | VRK1 | 1.81480584 |
| 16 | PIK3CG | 1.77767738 |
| 17 | ADRBK2 | 1.74998512 |
| 18 | NUAK1 | 1.72206090 |
| 19 | TESK2 | 1.67631076 |
| 20 | MAP3K12 | 1.53529896 |
| 21 | JAK3 | 1.47285210 |
| 22 | NME1 | 1.40310297 |
| 23 | GRK1 | 1.35402227 |
| 24 | FRK | 1.26268574 |
| 25 | INSRR | 1.24360578 |
| 26 | WNK4 | 1.24169372 |
| 27 | BMPR1B | 1.18221073 |
| 28 | OXSR1 | 1.07966751 |
| 29 | MAP2K6 | 1.01240601 |
| 30 | PLK3 | 1.01136554 |
| 31 | SRPK1 | 0.98681864 |
| 32 | MAP3K5 | 0.96963674 |
| 33 | TEC | 0.95804078 |
| 34 | TIE1 | 0.87783581 |
| 35 | EIF2AK2 | 0.87219517 |
| 36 | SYK | 0.86346814 |
| 37 | LIMK1 | 0.86109459 |
| 38 | LCK | 0.80132109 |
| 39 | BMPR2 | 0.79664889 |
| 40 | ERBB3 | 0.77607633 |
| 41 | MYLK | 0.76778128 |
| 42 | GRK5 | 0.73331299 |
| 43 | PIM2 | 0.73281566 |
| 44 | GRK7 | 0.70542130 |
| 45 | DYRK2 | 0.68002318 |
| 46 | TESK1 | 0.67398285 |
| 47 | DAPK3 | 0.66097062 |
| 48 | CSNK1G3 | 0.64201540 |
| 49 | STK39 | 0.63914268 |
| 50 | PINK1 | 0.63777604 |
| 51 | MAP4K1 | 0.62825930 |
| 52 | TAOK3 | 0.58436178 |
| 53 | PRKCQ | 0.57916783 |
| 54 | CAMK2D | 0.56746818 |
| 55 | MAP2K7 | 0.55009342 |
| 56 | LYN | 0.53798775 |
| 57 | ZAP70 | 0.53506908 |
| 58 | DAPK1 | 0.52719572 |
| 59 | FES | 0.52123587 |
| 60 | TTK | 0.51365617 |
| 61 | PHKG1 | 0.51278569 |
| 62 | PHKG2 | 0.51278569 |
| 63 | TSSK6 | 0.48974756 |
| 64 | NTRK3 | 0.47771862 |
| 65 | MINK1 | 0.46600160 |
| 66 | BTK | 0.45642118 |
| 67 | CSNK1A1 | 0.45015124 |
| 68 | IGF1R | 0.44758766 |
| 69 | CDC7 | 0.44668238 |
| 70 | CSNK1G1 | 0.43495439 |
| 71 | CSNK1A1L | 0.42923235 |
| 72 | CSK | 0.40873488 |
| 73 | CSNK1G2 | 0.40013718 |
| 74 | PLK2 | 0.39240453 |
| 75 | JAK2 | 0.39064529 |
| 76 | WNK3 | 0.38780555 |
| 77 | PRKCA | 0.38563868 |
| 78 | PIM1 | 0.37555485 |
| 79 | PRKCE | 0.36178813 |
| 80 | AURKA | 0.36064223 |
| 81 | ROCK1 | 0.35700076 |
| 82 | FYN | 0.35037438 |
| 83 | PNCK | 0.34573662 |
| 84 | ALK | 0.32147188 |
| 85 | CSNK2A1 | 0.32134502 |
| 86 | MAP4K2 | 0.31560739 |
| 87 | RPS6KA5 | 0.31314904 |
| 88 | CAMK2G | 0.30417758 |
| 89 | CAMK2A | 0.30231985 |
| 90 | OBSCN | 0.28606989 |
| 91 | ATR | 0.28434695 |
| 92 | ADRBK1 | 0.27905954 |
| 93 | PAK1 | 0.25934120 |
| 94 | PLK1 | 0.25611011 |
| 95 | FGFR2 | 0.25516450 |
| 96 | PRKCH | 0.24467852 |
| 97 | WNK1 | 0.24420009 |
| 98 | FLT3 | 0.23575611 |
| 99 | PRKCB | 0.22733891 |
| 100 | CAMK1G | 0.22411019 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.51860943 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 4.04570037 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.84314041 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.62367697 |
| 5 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.47012640 |
| 6 | Protein export_Homo sapiens_hsa03060 | 3.22370114 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.15647689 |
| 8 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.93558756 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.76897967 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.69093024 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.22673484 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.01124433 |
| 13 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.96258200 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.88273505 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.85962181 |
| 16 | Salmonella infection_Homo sapiens_hsa05132 | 1.77573367 |
| 17 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.69031907 |
| 18 | Alzheimers disease_Homo sapiens_hsa05010 | 1.52758689 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.47197307 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.43697510 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.43415733 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.38540010 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.38364424 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.27892389 |
| 25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.27773835 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.24181608 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.23655306 |
| 28 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.23601635 |
| 29 | Homologous recombination_Homo sapiens_hsa03440 | 1.15798243 |
| 30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.15740046 |
| 31 | Ribosome_Homo sapiens_hsa03010 | 1.07776268 |
| 32 | DNA replication_Homo sapiens_hsa03030 | 1.05485412 |
| 33 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.04146936 |
| 34 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.03048505 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.01921561 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.01710035 |
| 37 | Viral myocarditis_Homo sapiens_hsa05416 | 0.99655333 |
| 38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.99038204 |
| 39 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.92619337 |
| 40 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.82000870 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 0.78951864 |
| 42 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.78443917 |
| 43 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.76034916 |
| 44 | Measles_Homo sapiens_hsa05162 | 0.75666053 |
| 45 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.75442149 |
| 46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.73789916 |
| 47 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.73170871 |
| 48 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.72982711 |
| 49 | Spliceosome_Homo sapiens_hsa03040 | 0.69779204 |
| 50 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.69675504 |
| 51 | Malaria_Homo sapiens_hsa05144 | 0.68232824 |
| 52 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.66304266 |
| 53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.65506645 |
| 54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.63897800 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.62580610 |
| 56 | Phototransduction_Homo sapiens_hsa04744 | 0.61940907 |
| 57 | RNA degradation_Homo sapiens_hsa03018 | 0.61195331 |
| 58 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59742162 |
| 59 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.57881277 |
| 60 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.57382585 |
| 61 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.53702291 |
| 62 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.53145516 |
| 63 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.52790047 |
| 64 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52047071 |
| 65 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.51280915 |
| 66 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51067401 |
| 67 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.51027737 |
| 68 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.50745387 |
| 69 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.47880456 |
| 70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.47759049 |
| 71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47060286 |
| 72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.46541917 |
| 73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.45062999 |
| 74 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.44358226 |
| 75 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.44060311 |
| 76 | RNA transport_Homo sapiens_hsa03013 | 0.43293564 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.40328069 |
| 78 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.39162927 |
| 79 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.38509042 |
| 80 | Olfactory transduction_Homo sapiens_hsa04740 | 0.37478470 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.37225236 |
| 82 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.35753464 |
| 83 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.35131451 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.34490315 |
| 85 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.32929711 |
| 86 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.30819104 |
| 87 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.27754012 |
| 88 | Mineral absorption_Homo sapiens_hsa04978 | 0.27446140 |
| 89 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.26195477 |
| 90 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.22332262 |
| 91 | HTLV-I infection_Homo sapiens_hsa05166 | 0.21594610 |
| 92 | Alcoholism_Homo sapiens_hsa05034 | 0.18685525 |
| 93 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.18376261 |
| 94 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.17967345 |
| 95 | Shigellosis_Homo sapiens_hsa05131 | 0.17397478 |
| 96 | Leishmaniasis_Homo sapiens_hsa05140 | 0.15978733 |
| 97 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.15895727 |
| 98 | Base excision repair_Homo sapiens_hsa03410 | 0.15482945 |
| 99 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.14763160 |
| 100 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.14249874 |

