

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 9.84929529 |
| 2 | regulation of vitamin D biosynthetic process (GO:0060556) | 9.37038235 |
| 3 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 9.36757383 |
| 4 | negative regulation of metanephros development (GO:0072217) | 9.20002804 |
| 5 | negative regulation of interleukin-17 production (GO:0032700) | 8.08123010 |
| 6 | regulation of isotype switching to IgG isotypes (GO:0048302) | 8.04848752 |
| 7 | regulation of vitamin metabolic process (GO:0030656) | 7.70077206 |
| 8 | regulation of MHC class II biosynthetic process (GO:0045346) | 7.65130088 |
| 9 | positive regulation of chemokine biosynthetic process (GO:0045080) | 7.62190284 |
| 10 | negative regulation of neurological system process (GO:0031645) | 7.28463310 |
| 11 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 7.00616023 |
| 12 | positive regulation of isotype switching (GO:0045830) | 6.79737236 |
| 13 | positive regulation of DNA recombination (GO:0045911) | 6.16248559 |
| 14 | positive regulation of osteoclast differentiation (GO:0045672) | 5.89870327 |
| 15 | positive regulation of muscle cell apoptotic process (GO:0010661) | 5.80391980 |
| 16 | negative regulation of growth of symbiont in host (GO:0044130) | 5.72713144 |
| 17 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 5.72713144 |
| 18 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 5.72713144 |
| 19 | regulation of growth of symbiont in host (GO:0044126) | 5.72713144 |
| 20 | regulation of chemokine biosynthetic process (GO:0045073) | 5.65773864 |
| 21 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 5.56199931 |
| 22 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.55211566 |
| 23 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 5.42824053 |
| 24 | positive regulation of steroid biosynthetic process (GO:0010893) | 5.35100570 |
| 25 | regulation of smooth muscle cell apoptotic process (GO:0034391) | 5.29529049 |
| 26 | regulation of nephron tubule epithelial cell differentiation (GO:0072182) | 5.24313698 |
| 27 | negative regulation of kidney development (GO:0090185) | 5.23966170 |
| 28 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 4.98833634 |
| 29 | alpha-beta T cell activation involved in immune response (GO:0002287) | 4.98833634 |
| 30 | T cell differentiation involved in immune response (GO:0002292) | 4.98833634 |
| 31 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 4.96222860 |
| 32 | myeloid dendritic cell differentiation (GO:0043011) | 4.91696352 |
| 33 | defense response to protozoan (GO:0042832) | 4.86141064 |
| 34 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.82143106 |
| 35 | positive regulation of monooxygenase activity (GO:0032770) | 4.79563108 |
| 36 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 4.75691759 |
| 37 | regulation of epithelial cell differentiation involved in kidney development (GO:2000696) | 4.74367776 |
| 38 | positive regulation of interleukin-1 secretion (GO:0050716) | 4.66104919 |
| 39 | leukocyte apoptotic process (GO:0071887) | 4.61784855 |
| 40 | positive regulation of organelle assembly (GO:1902117) | 4.59914316 |
| 41 | regulation of interleukin-1 beta secretion (GO:0050706) | 4.56118487 |
| 42 | regulation of interleukin-17 production (GO:0032660) | 4.35288519 |
| 43 | myeloid dendritic cell activation (GO:0001773) | 4.33134036 |
| 44 | regulation of isotype switching (GO:0045191) | 4.32788141 |
| 45 | positive regulation of B cell mediated immunity (GO:0002714) | 4.28959425 |
| 46 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 4.28959425 |
| 47 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 4.22995532 |
| 48 | positive regulation of interleukin-12 production (GO:0032735) | 4.06847352 |
| 49 | regulation of interleukin-1 secretion (GO:0050704) | 4.00528262 |
| 50 | positive regulation of alcohol biosynthetic process (GO:1902932) | 3.97451783 |
| 51 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.95988988 |
| 52 | response to protozoan (GO:0001562) | 3.94246933 |
| 53 | positive regulation of phosphatase activity (GO:0010922) | 3.82342765 |
| 54 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.74370863 |
| 55 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.72552074 |
| 56 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.72552074 |
| 57 | isotype switching (GO:0045190) | 3.72552074 |
| 58 | regulation of metanephros development (GO:0072215) | 3.71248655 |
| 59 | positive regulation of interleukin-1 beta production (GO:0032731) | 3.68427326 |
| 60 | positive regulation of immunoglobulin production (GO:0002639) | 3.62828285 |
| 61 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 3.59463510 |
| 62 | regulation of response to interferon-gamma (GO:0060330) | 3.51537674 |
| 63 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 3.43467095 |
| 64 | regulation of centriole replication (GO:0046599) | 3.42753929 |
| 65 | protein import into nucleus, translocation (GO:0000060) | 3.42444068 |
| 66 | regulation of myelination (GO:0031641) | 3.40206917 |
| 67 | response to pheromone (GO:0019236) | 3.37766075 |
| 68 | maturation of 5.8S rRNA (GO:0000460) | 3.31388996 |
| 69 | positive regulation of interleukin-1 production (GO:0032732) | 3.24116622 |
| 70 | positive regulation of JAK-STAT cascade (GO:0046427) | 3.16662773 |
| 71 | alpha-beta T cell differentiation (GO:0046632) | 3.14178834 |
| 72 | cullin deneddylation (GO:0010388) | 3.14029515 |
| 73 | regulation of immunoglobulin production (GO:0002637) | 3.09228044 |
| 74 | regulation of the force of heart contraction (GO:0002026) | 3.06678707 |
| 75 | ether lipid metabolic process (GO:0046485) | 3.02668631 |
| 76 | regulation of tyrosine phosphorylation of STAT protein (GO:0042509) | 2.98516501 |
| 77 | DNA deamination (GO:0045006) | 2.95721829 |
| 78 | dendritic cell differentiation (GO:0097028) | 2.94165721 |
| 79 | protein deneddylation (GO:0000338) | 2.92246579 |
| 80 | regulation of immunoglobulin mediated immune response (GO:0002889) | 2.90396179 |
| 81 | positive regulation of myeloid leukocyte differentiation (GO:0002763) | 2.84623942 |
| 82 | positive regulation of steroid metabolic process (GO:0045940) | 2.84567112 |
| 83 | regulation of B cell mediated immunity (GO:0002712) | 2.81695421 |
| 84 | regulation of regulatory T cell differentiation (GO:0045589) | 2.81159469 |
| 85 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.80445604 |
| 86 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.75320619 |
| 87 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 2.73651762 |
| 88 | regulation of interleukin-12 production (GO:0032655) | 2.68517860 |
| 89 | negative regulation of smooth muscle cell proliferation (GO:0048662) | 2.67838887 |
| 90 | positive regulation of oxidoreductase activity (GO:0051353) | 2.67757087 |
| 91 | alpha-beta T cell activation (GO:0046631) | 2.66802440 |
| 92 | cornea development in camera-type eye (GO:0061303) | 2.64078607 |
| 93 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.61188491 |
| 94 | retinal cone cell development (GO:0046549) | 2.57011299 |
| 95 | aldehyde catabolic process (GO:0046185) | 2.54527261 |
| 96 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 12.2272594 |
| 97 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 12.2272594 |
| 98 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 11.5098516 |
| 99 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 10.0055645 |
| 100 | regulation of podosome assembly (GO:0071801) | 10.0009095 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.03199113 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.39744047 |
| 3 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 4.01093832 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.75827292 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.47019617 |
| 6 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 3.44480944 |
| 7 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.44160169 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.00613402 |
| 9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.98418025 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.90806038 |
| 11 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.70168579 |
| 12 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.65834759 |
| 13 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.37053770 |
| 14 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.35971667 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.19420943 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.13445171 |
| 17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.12000792 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.10819811 |
| 19 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 2.08510363 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.08496498 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.05578571 |
| 22 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.96745616 |
| 23 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.91634906 |
| 24 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.89795959 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.85766625 |
| 26 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.81014376 |
| 27 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.75320952 |
| 28 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.74764778 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.67844654 |
| 30 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.62665318 |
| 31 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.60189268 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.57730718 |
| 33 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.56836770 |
| 34 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.53384588 |
| 35 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.52495960 |
| 36 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.52208478 |
| 37 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.51037872 |
| 38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.48937583 |
| 39 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.48847722 |
| 40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.47818508 |
| 41 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.42041473 |
| 42 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.36970831 |
| 43 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.33855724 |
| 44 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.33855724 |
| 45 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.32501567 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.31728183 |
| 47 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.30398499 |
| 48 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29903675 |
| 49 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29104012 |
| 50 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28844626 |
| 51 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.27923181 |
| 52 | P300_19829295_ChIP-Seq_ESCs_Human | 1.26784040 |
| 53 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.22975595 |
| 54 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.21945944 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21436031 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21436031 |
| 57 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.20510107 |
| 58 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.20209318 |
| 59 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.19244621 |
| 60 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.17415393 |
| 61 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.15873980 |
| 62 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.14530620 |
| 63 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.13756516 |
| 64 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.09916794 |
| 65 | GATA1_22025678_ChIP-Seq_K562_Human | 1.08960017 |
| 66 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.08591373 |
| 67 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.07870401 |
| 68 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.06066538 |
| 69 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.04075770 |
| 70 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.03323726 |
| 71 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.03318366 |
| 72 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.02069676 |
| 73 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.00663105 |
| 74 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.00232144 |
| 75 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.00111581 |
| 76 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.99841972 |
| 77 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99633445 |
| 78 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.99369169 |
| 79 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98747300 |
| 80 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.98648948 |
| 81 | STAT3_23295773_ChIP-Seq_U87_Human | 0.98362892 |
| 82 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.97947042 |
| 83 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.97872378 |
| 84 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.97575447 |
| 85 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97330935 |
| 86 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.96434183 |
| 87 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.95536847 |
| 88 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.94977637 |
| 89 | TCF4_23295773_ChIP-Seq_U87_Human | 0.94042030 |
| 90 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.93964235 |
| 91 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.93911802 |
| 92 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.92925966 |
| 93 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.92906458 |
| 94 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.91051314 |
| 95 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.89177035 |
| 96 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.88882376 |
| 97 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.88788795 |
| 98 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.88667610 |
| 99 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.88526852 |
| 100 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.88469636 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001873_stomach_inflammation | 7.94358981 |
| 2 | MP0004782_abnormal_surfactant_physiolog | 6.98506448 |
| 3 | MP0001835_abnormal_antigen_presentation | 6.10064268 |
| 4 | MP0010307_abnormal_tumor_latency | 4.81202829 |
| 5 | MP0001958_emphysema | 4.75218698 |
| 6 | MP0005671_abnormal_response_to | 3.89545161 |
| 7 | MP0009333_abnormal_splenocyte_physiolog | 3.39393459 |
| 8 | MP0009785_altered_susceptibility_to | 3.03311119 |
| 9 | MP0002405_respiratory_system_inflammati | 2.88043234 |
| 10 | MP0003436_decreased_susceptibility_to | 2.52873351 |
| 11 | MP0005387_immune_system_phenotype | 2.19623637 |
| 12 | MP0001790_abnormal_immune_system | 2.19623637 |
| 13 | MP0003186_abnormal_redox_activity | 2.19425838 |
| 14 | MP0002148_abnormal_hypersensitivity_rea | 2.18901675 |
| 15 | MP0009780_abnormal_chondrocyte_physiolo | 2.13611471 |
| 16 | MP0000685_abnormal_immune_system | 2.12821688 |
| 17 | MP0003950_abnormal_plasma_membrane | 2.03692136 |
| 18 | MP0005000_abnormal_immune_tolerance | 1.83497808 |
| 19 | MP0002933_joint_inflammation | 1.59399638 |
| 20 | MP0001800_abnormal_humoral_immune | 1.55512583 |
| 21 | MP0001881_abnormal_mammary_gland | 1.52127736 |
| 22 | MP0008877_abnormal_DNA_methylation | 1.46956693 |
| 23 | MP0005501_abnormal_skin_physiology | 1.42554164 |
| 24 | MP0001663_abnormal_digestive_system | 1.38603872 |
| 25 | MP0010155_abnormal_intestine_physiology | 1.38095577 |
| 26 | MP0003195_calcinosis | 1.26197581 |
| 27 | MP0005166_decreased_susceptibility_to | 1.23762597 |
| 28 | MP0005310_abnormal_salivary_gland | 1.17742339 |
| 29 | MP0008058_abnormal_DNA_repair | 1.15087839 |
| 30 | MP0000427_abnormal_hair_cycle | 1.14705657 |
| 31 | MP0009765_abnormal_xenobiotic_induced | 1.11470332 |
| 32 | MP0006035_abnormal_mitochondrial_morpho | 1.08444811 |
| 33 | MP0008569_lethality_at_weaning | 1.06003035 |
| 34 | MP0003806_abnormal_nucleotide_metabolis | 1.02815811 |
| 35 | MP0003448_altered_tumor_morphology | 1.02810853 |
| 36 | MP0005646_abnormal_pituitary_gland | 1.00558063 |
| 37 | MP0008775_abnormal_heart_ventricle | 1.00346170 |
| 38 | MP0004142_abnormal_muscle_tone | 0.96780929 |
| 39 | MP0006054_spinal_hemorrhage | 0.96613097 |
| 40 | MP0001533_abnormal_skeleton_physiology | 0.93126871 |
| 41 | MP0000569_abnormal_digit_pigmentation | 0.92986738 |
| 42 | MP0002138_abnormal_hepatobiliary_system | 0.91943250 |
| 43 | MP0010094_abnormal_chromosome_stability | 0.87143423 |
| 44 | MP0004133_heterotaxia | 0.86956068 |
| 45 | MP0002693_abnormal_pancreas_physiology | 0.85258941 |
| 46 | MP0006072_abnormal_retinal_apoptosis | 0.84565016 |
| 47 | MP0004147_increased_porphyrin_level | 0.84324435 |
| 48 | MP0005381_digestive/alimentary_phenotyp | 0.83856916 |
| 49 | MP0002234_abnormal_pharynx_morphology | 0.83820851 |
| 50 | MP0008872_abnormal_physiological_respon | 0.83645311 |
| 51 | MP0008875_abnormal_xenobiotic_pharmacok | 0.82805135 |
| 52 | MP0003567_abnormal_fetal_cardiomyocyte | 0.80528430 |
| 53 | MP0001501_abnormal_sleep_pattern | 0.80018967 |
| 54 | MP0001293_anophthalmia | 0.79884896 |
| 55 | MP0000689_abnormal_spleen_morphology | 0.77284564 |
| 56 | MP0008770_decreased_survivor_rate | 0.77260608 |
| 57 | MP0005551_abnormal_eye_electrophysiolog | 0.77074573 |
| 58 | MP0009764_decreased_sensitivity_to | 0.74872564 |
| 59 | MP0001119_abnormal_female_reproductive | 0.74753074 |
| 60 | MP0001502_abnormal_circadian_rhythm | 0.74198832 |
| 61 | MP0001853_heart_inflammation | 0.74050214 |
| 62 | MP0003252_abnormal_bile_duct | 0.73327335 |
| 63 | MP0002136_abnormal_kidney_physiology | 0.73275920 |
| 64 | MP0002254_reproductive_system_inflammat | 0.73051474 |
| 65 | MP0000358_abnormal_cell_content/ | 0.69997818 |
| 66 | MP0002452_abnormal_antigen_presenting | 0.69831912 |
| 67 | MP0002722_abnormal_immune_system | 0.69445304 |
| 68 | MP0000383_abnormal_hair_follicle | 0.68958371 |
| 69 | MP0005365_abnormal_bile_salt | 0.68211199 |
| 70 | MP0009697_abnormal_copulation | 0.67571737 |
| 71 | MP0003122_maternal_imprinting | 0.66344183 |
| 72 | MP0002420_abnormal_adaptive_immunity | 0.65612305 |
| 73 | MP0002723_abnormal_immune_serum | 0.64211326 |
| 74 | MP0001819_abnormal_immune_cell | 0.63377617 |
| 75 | MP0002419_abnormal_innate_immunity | 0.62392536 |
| 76 | MP0002166_altered_tumor_susceptibility | 0.60837545 |
| 77 | MP0006036_abnormal_mitochondrial_physio | 0.60230400 |
| 78 | MP0002019_abnormal_tumor_incidence | 0.59866843 |
| 79 | MP0010771_integument_phenotype | 0.59201645 |
| 80 | MP0003890_abnormal_embryonic-extraembry | 0.57590899 |
| 81 | MP0006292_abnormal_olfactory_placode | 0.56041274 |
| 82 | MP0002210_abnormal_sex_determination | 0.55544682 |
| 83 | MP0004197_abnormal_fetal_growth/weight/ | 0.55260608 |
| 84 | MP0002837_dystrophic_cardiac_calcinosis | 0.54089754 |
| 85 | MP0005390_skeleton_phenotype | 0.53991150 |
| 86 | MP0005319_abnormal_enzyme/_coenzyme | 0.53037264 |
| 87 | MP0001845_abnormal_inflammatory_respons | 0.52698638 |
| 88 | MP0008873_increased_physiological_sensi | 0.50066280 |
| 89 | MP0005084_abnormal_gallbladder_morpholo | 0.49098037 |
| 90 | MP0003936_abnormal_reproductive_system | 0.48051852 |
| 91 | MP0000627_abnormal_mammary_gland | 0.46973057 |
| 92 | MP0000653_abnormal_sex_gland | 0.46219449 |
| 93 | MP0001756_abnormal_urination | 0.45847457 |
| 94 | MP0005083_abnormal_biliary_tract | 0.45713687 |
| 95 | MP0001175_abnormal_lung_morphology | 0.44928710 |
| 96 | MP0005388_respiratory_system_phenotype | 0.44586238 |
| 97 | MP0002133_abnormal_respiratory_system | 0.44586238 |
| 98 | MP0001764_abnormal_homeostasis | 0.44250245 |
| 99 | MP0008438_abnormal_cutaneous_collagen | 0.43534427 |
| 100 | MP0005253_abnormal_eye_physiology | 0.42909671 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 4.98619409 |
| 2 | IgA deficiency (HP:0002720) | 4.61573883 |
| 3 | Type 2 muscle fiber atrophy (HP:0003554) | 4.47425062 |
| 4 | Abnormality of the pons (HP:0007361) | 3.90443489 |
| 5 | Muscle fiber atrophy (HP:0100295) | 3.87904235 |
| 6 | Glucose intolerance (HP:0000833) | 3.70063536 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.57783012 |
| 8 | Attenuation of retinal blood vessels (HP:0007843) | 3.56732608 |
| 9 | Hypoplasia of the pons (HP:0012110) | 3.48428133 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.47457327 |
| 11 | Aplasia/hypoplasia of the humerus (HP:0006507) | 3.33308799 |
| 12 | Acute encephalopathy (HP:0006846) | 3.32889291 |
| 13 | Carpal bone hypoplasia (HP:0001498) | 3.20473983 |
| 14 | Short humerus (HP:0005792) | 3.18729926 |
| 15 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.04125524 |
| 16 | Biconcave vertebral bodies (HP:0004586) | 3.01418459 |
| 17 | Prolonged partial thromboplastin time (HP:0003645) | 2.92860346 |
| 18 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.92830148 |
| 19 | Increased CSF lactate (HP:0002490) | 2.91272401 |
| 20 | Mitochondrial inheritance (HP:0001427) | 2.88122824 |
| 21 | Abnormality of T cells (HP:0002843) | 2.86319964 |
| 22 | IgG deficiency (HP:0004315) | 2.83241071 |
| 23 | Central scotoma (HP:0000603) | 2.79636796 |
| 24 | Chronic diarrhea (HP:0002028) | 2.75223406 |
| 25 | Abnormal glucose tolerance (HP:0001952) | 2.72090933 |
| 26 | T lymphocytopenia (HP:0005403) | 2.66450149 |
| 27 | Increased IgM level (HP:0003496) | 2.65131157 |
| 28 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.64571743 |
| 29 | Aplastic anemia (HP:0001915) | 2.62712752 |
| 30 | Oligomenorrhea (HP:0000876) | 2.62293056 |
| 31 | Abnormality of T cell number (HP:0011839) | 2.56545585 |
| 32 | Asplenia (HP:0001746) | 2.52083094 |
| 33 | Abnormality of T cell physiology (HP:0011840) | 2.51883502 |
| 34 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.47554687 |
| 35 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.47492140 |
| 36 | Alkalosis (HP:0001948) | 2.41298438 |
| 37 | Chronic sinusitis (HP:0011109) | 2.40500726 |
| 38 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.36880050 |
| 39 | Posterior subcapsular cataract (HP:0007787) | 2.32566314 |
| 40 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.31779040 |
| 41 | Absent epiphyses (HP:0010577) | 2.28607334 |
| 42 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.28607334 |
| 43 | Abnormality of the costochondral junction (HP:0000919) | 2.27793280 |
| 44 | Irregular vertebral endplates (HP:0003301) | 2.27720233 |
| 45 | Increased serum pyruvate (HP:0003542) | 2.22246818 |
| 46 | Short 1st metacarpal (HP:0010034) | 2.21244854 |
| 47 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.21244854 |
| 48 | Neonatal respiratory distress (HP:0002643) | 2.20293674 |
| 49 | Horizontal nystagmus (HP:0000666) | 2.20191911 |
| 50 | Cerebral edema (HP:0002181) | 2.17731898 |
| 51 | Hepatocellular necrosis (HP:0001404) | 2.14189532 |
| 52 | Inability to walk (HP:0002540) | 2.12756442 |
| 53 | Cerebral hypomyelination (HP:0006808) | 2.12542301 |
| 54 | Thyroiditis (HP:0100646) | 2.12473946 |
| 55 | Pancreatic cysts (HP:0001737) | 2.09784319 |
| 56 | Prominent metopic ridge (HP:0005487) | 2.09085006 |
| 57 | Progressive microcephaly (HP:0000253) | 2.03357743 |
| 58 | Delayed epiphyseal ossification (HP:0002663) | 2.02472707 |
| 59 | Abnormality of the prostate (HP:0008775) | 2.00347090 |
| 60 | Scotoma (HP:0000575) | 1.98804954 |
| 61 | Constricted visual fields (HP:0001133) | 1.94716374 |
| 62 | Duplicated collecting system (HP:0000081) | 1.93506741 |
| 63 | Hepatic necrosis (HP:0002605) | 1.92996113 |
| 64 | Abnormality of the 1st metacarpal (HP:0010009) | 1.92830243 |
| 65 | Abolished electroretinogram (ERG) (HP:0000550) | 1.92766640 |
| 66 | Poor head control (HP:0002421) | 1.92203549 |
| 67 | Irregular epiphyses (HP:0010582) | 1.91909431 |
| 68 | Abnormality of the metopic suture (HP:0005556) | 1.91575851 |
| 69 | Increased serum lactate (HP:0002151) | 1.91492398 |
| 70 | Abnormality of the vertebral endplates (HP:0005106) | 1.91178917 |
| 71 | Metabolic alkalosis (HP:0200114) | 1.90542117 |
| 72 | Thyroid-stimulating hormone excess (HP:0002925) | 1.89695965 |
| 73 | Abnormality of the labia minora (HP:0012880) | 1.89616305 |
| 74 | Autoimmune hemolytic anemia (HP:0001890) | 1.88544039 |
| 75 | Type I transferrin isoform profile (HP:0003642) | 1.87184443 |
| 76 | Congenital stationary night blindness (HP:0007642) | 1.85782261 |
| 77 | Optic disc pallor (HP:0000543) | 1.85284286 |
| 78 | Congenital, generalized hypertrichosis (HP:0004540) | 1.84660640 |
| 79 | Polyuria (HP:0000103) | 1.83947285 |
| 80 | Renal salt wasting (HP:0000127) | 1.83614343 |
| 81 | Enlarged epiphyses (HP:0010580) | 1.82313471 |
| 82 | Recurrent fungal infections (HP:0002841) | 1.81698402 |
| 83 | Abnormality of DNA repair (HP:0003254) | 1.81612945 |
| 84 | Disproportionate short-trunk short stature (HP:0003521) | 1.80109373 |
| 85 | Neutropenia (HP:0001875) | 1.79869280 |
| 86 | Abnormality of the renal collecting system (HP:0004742) | 1.76580889 |
| 87 | Dyschromatopsia (HP:0007641) | 1.74913793 |
| 88 | Flattened epiphyses (HP:0003071) | 1.74216194 |
| 89 | Small hand (HP:0200055) | 1.74128529 |
| 90 | True hermaphroditism (HP:0010459) | 1.72891127 |
| 91 | Joint swelling (HP:0001386) | 1.71970565 |
| 92 | Hypokalemic alkalosis (HP:0001949) | 1.69810756 |
| 93 | Molar tooth sign on MRI (HP:0002419) | 1.69624878 |
| 94 | Abnormality of midbrain morphology (HP:0002418) | 1.69624878 |
| 95 | Small epiphyses (HP:0010585) | 1.69011627 |
| 96 | Keratoconjunctivitis (HP:0001096) | 1.68561105 |
| 97 | Keratoconus (HP:0000563) | 1.68370526 |
| 98 | Increased corneal curvature (HP:0100692) | 1.68370526 |
| 99 | Metaphyseal irregularity (HP:0003025) | 1.67912523 |
| 100 | Hypoproteinemia (HP:0003075) | 1.67580055 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.69002036 |
| 2 | EIF2AK3 | 5.16325723 |
| 3 | NME1 | 4.39672078 |
| 4 | FRK | 4.02737472 |
| 5 | EIF2AK1 | 3.53356595 |
| 6 | MST4 | 2.73267891 |
| 7 | FLT3 | 2.44715843 |
| 8 | ADRBK2 | 2.17349187 |
| 9 | BMPR1B | 2.12683281 |
| 10 | TSSK6 | 2.08337834 |
| 11 | ACVR1B | 2.01678584 |
| 12 | CAMKK2 | 1.88743905 |
| 13 | SRPK1 | 1.84841119 |
| 14 | WNK1 | 1.82686953 |
| 15 | BUB1 | 1.79296271 |
| 16 | GRK1 | 1.78657115 |
| 17 | TLK1 | 1.71151487 |
| 18 | PDK2 | 1.70803512 |
| 19 | TNIK | 1.65254538 |
| 20 | VRK2 | 1.64408566 |
| 21 | PLK3 | 1.62269649 |
| 22 | TNK2 | 1.59732138 |
| 23 | PKN2 | 1.46743491 |
| 24 | EIF2AK2 | 1.45033674 |
| 25 | PRKD3 | 1.43702383 |
| 26 | VRK1 | 1.29325341 |
| 27 | FGFR1 | 1.15429632 |
| 28 | TAOK3 | 1.13971595 |
| 29 | MAP4K2 | 1.13187427 |
| 30 | ZAK | 1.13158806 |
| 31 | WNK3 | 1.12339669 |
| 32 | AKT3 | 1.10562920 |
| 33 | INSRR | 0.99766058 |
| 34 | DDR2 | 0.98511942 |
| 35 | MAP2K6 | 0.98505944 |
| 36 | MAP3K7 | 0.92050113 |
| 37 | NUAK1 | 0.90543615 |
| 38 | ALK | 0.90228864 |
| 39 | PAK3 | 0.88068945 |
| 40 | NLK | 0.87533437 |
| 41 | PLK2 | 0.86414749 |
| 42 | PLK1 | 0.79107499 |
| 43 | TGFBR1 | 0.78853657 |
| 44 | KIT | 0.76825779 |
| 45 | MKNK1 | 0.76805304 |
| 46 | PIK3CG | 0.76702634 |
| 47 | NEK6 | 0.73197622 |
| 48 | MKNK2 | 0.69084909 |
| 49 | STK38 | 0.66835051 |
| 50 | ADRBK1 | 0.64527828 |
| 51 | ERBB3 | 0.64136510 |
| 52 | MAPK13 | 0.64006310 |
| 53 | STK10 | 0.63953287 |
| 54 | TRIM28 | 0.63110506 |
| 55 | MAP4K1 | 0.62261548 |
| 56 | CDK6 | 0.58010296 |
| 57 | TIE1 | 0.56626062 |
| 58 | IKBKB | 0.55275843 |
| 59 | STK39 | 0.51948856 |
| 60 | PDGFRB | 0.49886143 |
| 61 | OXSR1 | 0.48513381 |
| 62 | UHMK1 | 0.47454494 |
| 63 | MAP3K12 | 0.46558172 |
| 64 | FGFR2 | 0.45177740 |
| 65 | SYK | 0.45166081 |
| 66 | STK38L | 0.45106041 |
| 67 | CHUK | 0.45004449 |
| 68 | MUSK | 0.43842856 |
| 69 | PINK1 | 0.43209388 |
| 70 | PHKG2 | 0.42079375 |
| 71 | PHKG1 | 0.42079375 |
| 72 | STK4 | 0.40257607 |
| 73 | JAK3 | 0.39159890 |
| 74 | WNK4 | 0.38586096 |
| 75 | PIK3CA | 0.35942053 |
| 76 | LCK | 0.35922201 |
| 77 | ATM | 0.35486489 |
| 78 | LATS1 | 0.33910930 |
| 79 | PRKCE | 0.33723837 |
| 80 | PTK2B | 0.32504139 |
| 81 | PRKCI | 0.31178949 |
| 82 | TYK2 | 0.30604050 |
| 83 | PNCK | 0.30110399 |
| 84 | BRSK2 | 0.30097959 |
| 85 | PRKCG | 0.28883287 |
| 86 | PRKCA | 0.28784414 |
| 87 | MAP3K4 | 0.28635712 |
| 88 | RPS6KA5 | 0.27354758 |
| 89 | PRKCH | 0.25675048 |
| 90 | CAMKK1 | 0.25529537 |
| 91 | JAK2 | 0.25419755 |
| 92 | PRKCB | 0.25214212 |
| 93 | BCKDK | 0.24608997 |
| 94 | PRKACA | 0.23872604 |
| 95 | STK11 | 0.22493232 |
| 96 | DAPK2 | 0.22292686 |
| 97 | WEE1 | 0.20289853 |
| 98 | OBSCN | 0.20013369 |
| 99 | EPHA4 | 0.19319253 |
| 100 | GRK6 | 0.18695796 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 7.31430144 |
| 2 | Regulation of autophagy_Homo sapiens_hsa04140 | 3.62799037 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.17794168 |
| 4 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 3.12275360 |
| 5 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.81203706 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.78048516 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.77097555 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.71957713 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.37873950 |
| 10 | African trypanosomiasis_Homo sapiens_hsa05143 | 2.35860295 |
| 11 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.99357166 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.95275497 |
| 13 | Malaria_Homo sapiens_hsa05144 | 1.87411057 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.78300556 |
| 15 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.75317179 |
| 16 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.74825711 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.63757957 |
| 18 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.56972879 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.43098349 |
| 20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.42348470 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.41415939 |
| 22 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.39902599 |
| 23 | Salmonella infection_Homo sapiens_hsa05132 | 1.37512922 |
| 24 | Amoebiasis_Homo sapiens_hsa05146 | 1.33467767 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.32522391 |
| 26 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.30397503 |
| 27 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.29397010 |
| 28 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.27435026 |
| 29 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.16857769 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.16516420 |
| 31 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.12983638 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.09599065 |
| 33 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.08793544 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.00489595 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.97277067 |
| 36 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.96806259 |
| 37 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.94682930 |
| 38 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.94398491 |
| 39 | Parkinsons disease_Homo sapiens_hsa05012 | 0.93430933 |
| 40 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.90357404 |
| 41 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.89249438 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 0.88292745 |
| 43 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.85918543 |
| 44 | Measles_Homo sapiens_hsa05162 | 0.84184342 |
| 45 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.84029672 |
| 46 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.83155964 |
| 47 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82407547 |
| 48 | RNA degradation_Homo sapiens_hsa03018 | 0.80519315 |
| 49 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.80283133 |
| 50 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.78576973 |
| 51 | Asthma_Homo sapiens_hsa05310 | 0.77287257 |
| 52 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.72746386 |
| 53 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.71015895 |
| 54 | Huntingtons disease_Homo sapiens_hsa05016 | 0.70550855 |
| 55 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.69116696 |
| 56 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.66626368 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.64776687 |
| 58 | Taste transduction_Homo sapiens_hsa04742 | 0.61861429 |
| 59 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.58657053 |
| 60 | Leishmaniasis_Homo sapiens_hsa05140 | 0.56387609 |
| 61 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.54903916 |
| 62 | RNA transport_Homo sapiens_hsa03013 | 0.54032172 |
| 63 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.52966199 |
| 64 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.51972447 |
| 65 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51203128 |
| 66 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.49662020 |
| 67 | Ribosome_Homo sapiens_hsa03010 | 0.48864907 |
| 68 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.48823587 |
| 69 | Mismatch repair_Homo sapiens_hsa03430 | 0.47960519 |
| 70 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.47513485 |
| 71 | Spliceosome_Homo sapiens_hsa03040 | 0.46390240 |
| 72 | Phototransduction_Homo sapiens_hsa04744 | 0.46190659 |
| 73 | Purine metabolism_Homo sapiens_hsa00230 | 0.45947724 |
| 74 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.45051268 |
| 75 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.42433933 |
| 76 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.42382618 |
| 77 | ABC transporters_Homo sapiens_hsa02010 | 0.39798324 |
| 78 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.37137856 |
| 79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36993077 |
| 80 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.36916453 |
| 81 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.35717368 |
| 82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34766021 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34196504 |
| 84 | Mineral absorption_Homo sapiens_hsa04978 | 0.32438887 |
| 85 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.31757795 |
| 86 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.31627460 |
| 87 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.31455448 |
| 88 | Olfactory transduction_Homo sapiens_hsa04740 | 0.31241541 |
| 89 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.29882075 |
| 90 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.28927888 |
| 91 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.28689563 |
| 92 | Alzheimers disease_Homo sapiens_hsa05010 | 0.25905790 |
| 93 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.25252235 |
| 94 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.24784908 |
| 95 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.24516675 |
| 96 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.23160635 |
| 97 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.23160262 |
| 98 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.22569880 |
| 99 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.21565979 |
| 100 | Metabolic pathways_Homo sapiens_hsa01100 | 0.21545086 |

