

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.36089201 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.99527928 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.99527928 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.70650996 |
| 5 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.53093880 |
| 6 | protein neddylation (GO:0045116) | 4.52872066 |
| 7 | protein complex biogenesis (GO:0070271) | 4.27538871 |
| 8 | kynurenine metabolic process (GO:0070189) | 4.22103367 |
| 9 | respiratory electron transport chain (GO:0022904) | 4.04419516 |
| 10 | electron transport chain (GO:0022900) | 4.02647061 |
| 11 | tryptophan catabolic process (GO:0006569) | 4.02291493 |
| 12 | indole-containing compound catabolic process (GO:0042436) | 4.02291493 |
| 13 | indolalkylamine catabolic process (GO:0046218) | 4.02291493 |
| 14 | tryptophan metabolic process (GO:0006568) | 3.95529012 |
| 15 | base-excision repair, AP site formation (GO:0006285) | 3.94825985 |
| 16 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.89087357 |
| 17 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.85107608 |
| 18 | regulation of cilium movement (GO:0003352) | 3.80521613 |
| 19 | indolalkylamine metabolic process (GO:0006586) | 3.78643699 |
| 20 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.78107087 |
| 21 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.78107087 |
| 22 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.66695163 |
| 23 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.66695163 |
| 24 | NADH dehydrogenase complex assembly (GO:0010257) | 3.66695163 |
| 25 | ribosomal small subunit assembly (GO:0000028) | 3.65586106 |
| 26 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.60782975 |
| 27 | respiratory chain complex IV assembly (GO:0008535) | 3.59491432 |
| 28 | cytochrome complex assembly (GO:0017004) | 3.51003499 |
| 29 | protein-cofactor linkage (GO:0018065) | 3.49322980 |
| 30 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.47586889 |
| 31 | chaperone-mediated protein transport (GO:0072321) | 3.45408800 |
| 32 | maturation of 5.8S rRNA (GO:0000460) | 3.37818703 |
| 33 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.36339226 |
| 34 | mannosylation (GO:0097502) | 3.36282837 |
| 35 | piRNA metabolic process (GO:0034587) | 3.34525604 |
| 36 | oxidative phosphorylation (GO:0006119) | 3.26460893 |
| 37 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.26013421 |
| 38 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.25174459 |
| 39 | L-fucose catabolic process (GO:0042355) | 3.20435427 |
| 40 | fucose catabolic process (GO:0019317) | 3.20435427 |
| 41 | L-fucose metabolic process (GO:0042354) | 3.20435427 |
| 42 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.18082056 |
| 43 | ATP biosynthetic process (GO:0006754) | 3.14287420 |
| 44 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.07075953 |
| 45 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.05793224 |
| 46 | GPI anchor metabolic process (GO:0006505) | 3.03544487 |
| 47 | hydrogen ion transmembrane transport (GO:1902600) | 3.00020803 |
| 48 | GPI anchor biosynthetic process (GO:0006506) | 2.99942254 |
| 49 | rRNA catabolic process (GO:0016075) | 2.99828459 |
| 50 | spliceosomal complex assembly (GO:0000245) | 2.99384349 |
| 51 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.98220547 |
| 52 | aldehyde catabolic process (GO:0046185) | 2.97827259 |
| 53 | protein polyglutamylation (GO:0018095) | 2.95561869 |
| 54 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.93296088 |
| 55 | L-methionine salvage (GO:0071267) | 2.89966131 |
| 56 | L-methionine biosynthetic process (GO:0071265) | 2.89966131 |
| 57 | amino acid salvage (GO:0043102) | 2.89966131 |
| 58 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.89671911 |
| 59 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.89176214 |
| 60 | behavioral response to nicotine (GO:0035095) | 2.87990617 |
| 61 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.87804265 |
| 62 | termination of RNA polymerase III transcription (GO:0006386) | 2.87804265 |
| 63 | S-adenosylmethionine metabolic process (GO:0046500) | 2.87657592 |
| 64 | proton transport (GO:0015992) | 2.84085917 |
| 65 | amine catabolic process (GO:0009310) | 2.83772522 |
| 66 | cellular biogenic amine catabolic process (GO:0042402) | 2.83772522 |
| 67 | hydrogen transport (GO:0006818) | 2.81846797 |
| 68 | ubiquinone biosynthetic process (GO:0006744) | 2.81138797 |
| 69 | proteasome assembly (GO:0043248) | 2.80653544 |
| 70 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.80476074 |
| 71 | GTP biosynthetic process (GO:0006183) | 2.78894936 |
| 72 | branched-chain amino acid catabolic process (GO:0009083) | 2.78165040 |
| 73 | positive regulation of prostaglandin secretion (GO:0032308) | 2.77934456 |
| 74 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.75975680 |
| 75 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.75975680 |
| 76 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.75975680 |
| 77 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.72503794 |
| 78 | tRNA processing (GO:0008033) | 2.70973961 |
| 79 | maturation of SSU-rRNA (GO:0030490) | 2.69986448 |
| 80 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.67723994 |
| 81 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.67723994 |
| 82 | mast cell activation involved in immune response (GO:0002279) | 2.63361977 |
| 83 | mast cell degranulation (GO:0043303) | 2.63361977 |
| 84 | regulation of microtubule-based movement (GO:0060632) | 2.62877975 |
| 85 | axoneme assembly (GO:0035082) | 2.62213540 |
| 86 | epithelial cilium movement (GO:0003351) | 2.61490178 |
| 87 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.59641059 |
| 88 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.57690491 |
| 89 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.57690491 |
| 90 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.57213850 |
| 91 | deoxyribonucleotide catabolic process (GO:0009264) | 2.57140746 |
| 92 | RNA phosphodiester bond hydrolysis (GO:0090501) | 2.55766062 |
| 93 | indole-containing compound metabolic process (GO:0042430) | 2.54991352 |
| 94 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.53071647 |
| 95 | cytidine metabolic process (GO:0046087) | 2.53071609 |
| 96 | cytidine catabolic process (GO:0006216) | 2.53071609 |
| 97 | cytidine deamination (GO:0009972) | 2.53071609 |
| 98 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.51808062 |
| 99 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.51808062 |
| 100 | isotype switching (GO:0045190) | 2.51808062 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.10183341 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.95045730 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.55691569 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.42580473 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.21848396 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.15029932 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.98145395 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.94605550 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.77563940 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.73389468 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.65171220 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.63222765 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.52462859 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.50893004 |
| 15 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.30877020 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.25664475 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.20048059 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.16362622 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.02891430 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.85100290 |
| 21 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.84218065 |
| 22 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.83671928 |
| 23 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.81287124 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.81182210 |
| 25 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.80994577 |
| 26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.68796220 |
| 27 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.65757112 |
| 28 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.65658009 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.60891680 |
| 30 | EWS_26573619_Chip-Seq_HEK293_Human | 1.60649977 |
| 31 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.60566151 |
| 32 | FUS_26573619_Chip-Seq_HEK293_Human | 1.59218245 |
| 33 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.57556658 |
| 34 | AR_20517297_ChIP-Seq_VCAP_Human | 1.52668832 |
| 35 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.52389461 |
| 36 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.52389461 |
| 37 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.48767771 |
| 38 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.43973023 |
| 39 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.38160405 |
| 40 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.35236403 |
| 41 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.34720976 |
| 42 | GATA3_26560356_Chip-Seq_TH2_Human | 1.32257305 |
| 43 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.32241216 |
| 44 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31263644 |
| 45 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.30952233 |
| 46 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.30392589 |
| 47 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29425085 |
| 48 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.29270505 |
| 49 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.26757673 |
| 50 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.26733939 |
| 51 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.26277891 |
| 52 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.24422396 |
| 53 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.23636705 |
| 54 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.23286827 |
| 55 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.22310700 |
| 56 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.21604622 |
| 57 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.21393512 |
| 58 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.19397215 |
| 59 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18482247 |
| 60 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18429183 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18429183 |
| 62 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.17955068 |
| 63 | P300_19829295_ChIP-Seq_ESCs_Human | 1.17733467 |
| 64 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.17668612 |
| 65 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15593274 |
| 66 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.14622249 |
| 67 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.13599452 |
| 68 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.13294474 |
| 69 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.12869861 |
| 70 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.12869861 |
| 71 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.12499460 |
| 72 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.12029513 |
| 73 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.10104965 |
| 74 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.09768044 |
| 75 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.09002776 |
| 76 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08643878 |
| 77 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.07569592 |
| 78 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.06499409 |
| 79 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06011760 |
| 80 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.05977407 |
| 81 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.05108501 |
| 82 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.04442883 |
| 83 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03680084 |
| 84 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.03622415 |
| 85 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03172758 |
| 86 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.03080291 |
| 87 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02926894 |
| 88 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.01623392 |
| 89 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.01100107 |
| 90 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00597896 |
| 91 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00568790 |
| 92 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.00518599 |
| 93 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.98957939 |
| 94 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.98941468 |
| 95 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.97349510 |
| 96 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.96383827 |
| 97 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.96201820 |
| 98 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.95018111 |
| 99 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.92475855 |
| 100 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.91697563 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.08165457 |
| 2 | MP0004147_increased_porphyrin_level | 2.99774049 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 2.93294272 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.87974596 |
| 5 | MP0005646_abnormal_pituitary_gland | 2.52786591 |
| 6 | MP0003195_calcinosis | 2.36128359 |
| 7 | MP0008875_abnormal_xenobiotic_pharmacok | 2.28665606 |
| 8 | MP0005084_abnormal_gallbladder_morpholo | 2.26354184 |
| 9 | MP0003787_abnormal_imprinting | 2.16077910 |
| 10 | MP0008872_abnormal_physiological_respon | 2.15877095 |
| 11 | MP0002876_abnormal_thyroid_physiology | 2.11370218 |
| 12 | MP0005671_abnormal_response_to | 2.04957771 |
| 13 | MP0008995_early_reproductive_senescence | 1.99052258 |
| 14 | MP0001835_abnormal_antigen_presentation | 1.97098733 |
| 15 | MP0005075_abnormal_melanosome_morpholog | 1.96345372 |
| 16 | MP0004885_abnormal_endolymph | 1.94234129 |
| 17 | MP0005645_abnormal_hypothalamus_physiol | 1.92052054 |
| 18 | MP0002837_dystrophic_cardiac_calcinosis | 1.91493058 |
| 19 | MP0008058_abnormal_DNA_repair | 1.90763731 |
| 20 | MP0002102_abnormal_ear_morphology | 1.89129708 |
| 21 | MP0005551_abnormal_eye_electrophysiolog | 1.86817798 |
| 22 | MP0003786_premature_aging | 1.83010894 |
| 23 | MP0002234_abnormal_pharynx_morphology | 1.77889493 |
| 24 | MP0008775_abnormal_heart_ventricle | 1.75456493 |
| 25 | MP0000372_irregular_coat_pigmentation | 1.73539140 |
| 26 | MP0003724_increased_susceptibility_to | 1.72695296 |
| 27 | MP0004145_abnormal_muscle_electrophysio | 1.72303150 |
| 28 | MP0006036_abnormal_mitochondrial_physio | 1.65428707 |
| 29 | MP0003011_delayed_dark_adaptation | 1.59253664 |
| 30 | MP0005253_abnormal_eye_physiology | 1.58118031 |
| 31 | MP0003646_muscle_fatigue | 1.56088093 |
| 32 | MP0006276_abnormal_autonomic_nervous | 1.49654470 |
| 33 | MP0002148_abnormal_hypersensitivity_rea | 1.48538186 |
| 34 | MP0009046_muscle_twitch | 1.46572997 |
| 35 | MP0002138_abnormal_hepatobiliary_system | 1.43830177 |
| 36 | MP0005389_reproductive_system_phenotype | 1.40653213 |
| 37 | MP0004142_abnormal_muscle_tone | 1.40253572 |
| 38 | MP0009764_decreased_sensitivity_to | 1.39211328 |
| 39 | MP0009379_abnormal_foot_pigmentation | 1.37133930 |
| 40 | MP0002272_abnormal_nervous_system | 1.37073257 |
| 41 | MP0002736_abnormal_nociception_after | 1.35975319 |
| 42 | MP0001986_abnormal_taste_sensitivity | 1.34864110 |
| 43 | MP0006054_spinal_hemorrhage | 1.34402879 |
| 44 | MP0002163_abnormal_gland_morphology | 1.28373158 |
| 45 | MP0003252_abnormal_bile_duct | 1.28273476 |
| 46 | MP0001919_abnormal_reproductive_system | 1.27794000 |
| 47 | MP0001968_abnormal_touch/_nociception | 1.26993988 |
| 48 | MP0003186_abnormal_redox_activity | 1.26280659 |
| 49 | MP0001764_abnormal_homeostasis | 1.26276098 |
| 50 | MP0002160_abnormal_reproductive_system | 1.14531182 |
| 51 | MP0002006_tumorigenesis | 1.14358502 |
| 52 | MP0001800_abnormal_humoral_immune | 1.11689927 |
| 53 | MP0001501_abnormal_sleep_pattern | 1.10263060 |
| 54 | MP0003806_abnormal_nucleotide_metabolis | 1.09894715 |
| 55 | MP0003866_abnormal_defecation | 1.07141185 |
| 56 | MP0009785_altered_susceptibility_to | 1.07030378 |
| 57 | MP0006035_abnormal_mitochondrial_morpho | 1.06482940 |
| 58 | MP0005000_abnormal_immune_tolerance | 1.05875163 |
| 59 | MP0000230_abnormal_systemic_arterial | 1.05588430 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 1.03738337 |
| 61 | MP0003878_abnormal_ear_physiology | 1.03738337 |
| 62 | MP0005367_renal/urinary_system_phenotyp | 1.02363456 |
| 63 | MP0000516_abnormal_urinary_system | 1.02363456 |
| 64 | MP0000631_abnormal_neuroendocrine_gland | 1.01862457 |
| 65 | MP0001905_abnormal_dopamine_level | 1.00681523 |
| 66 | MP0005167_abnormal_blood-brain_barrier | 1.00327996 |
| 67 | MP0005636_abnormal_mineral_homeostasis | 1.00103458 |
| 68 | MP0003880_abnormal_central_pattern | 0.99791142 |
| 69 | MP0002166_altered_tumor_susceptibility | 0.99653933 |
| 70 | MP0002928_abnormal_bile_duct | 0.97760587 |
| 71 | MP0001542_abnormal_bone_strength | 0.97019806 |
| 72 | MP0005332_abnormal_amino_acid | 0.96556225 |
| 73 | MP0008789_abnormal_olfactory_epithelium | 0.95753899 |
| 74 | MP0003718_maternal_effect | 0.94277852 |
| 75 | MP0009745_abnormal_behavioral_response | 0.93777535 |
| 76 | MP0009333_abnormal_splenocyte_physiolog | 0.93501756 |
| 77 | MP0001293_anophthalmia | 0.92577655 |
| 78 | MP0001970_abnormal_pain_threshold | 0.92553538 |
| 79 | MP0010386_abnormal_urinary_bladder | 0.91262649 |
| 80 | MP0001529_abnormal_vocalization | 0.90438238 |
| 81 | MP0002723_abnormal_immune_serum | 0.90275196 |
| 82 | MP0001765_abnormal_ion_homeostasis | 0.89846821 |
| 83 | MP0002733_abnormal_thermal_nociception | 0.88917308 |
| 84 | MP0005085_abnormal_gallbladder_physiolo | 0.87412218 |
| 85 | MP0005410_abnormal_fertilization | 0.86708930 |
| 86 | MP0002452_abnormal_antigen_presenting | 0.86439786 |
| 87 | MP0002277_abnormal_respiratory_mucosa | 0.79681006 |
| 88 | MP0003121_genomic_imprinting | 0.79662567 |
| 89 | MP0003137_abnormal_impulse_conducting | 0.77049866 |
| 90 | MP0004215_abnormal_myocardial_fiber | 0.76735493 |
| 91 | MP0001485_abnormal_pinna_reflex | 0.75386977 |
| 92 | MP0001756_abnormal_urination | 0.75253352 |
| 93 | MP0001440_abnormal_grooming_behavior | 0.74732582 |
| 94 | MP0002572_abnormal_emotion/affect_behav | 0.73652436 |
| 95 | MP0001819_abnormal_immune_cell | 0.71995495 |
| 96 | MP0001984_abnormal_olfaction | 0.70601521 |
| 97 | MP0009780_abnormal_chondrocyte_physiolo | 0.70403585 |
| 98 | MP0002282_abnormal_trachea_morphology | 0.70147985 |
| 99 | MP0002751_abnormal_autonomic_nervous | 0.69638537 |
| 100 | MP0002420_abnormal_adaptive_immunity | 0.69561388 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.42651086 |
| 2 | Acute encephalopathy (HP:0006846) | 4.29048595 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.21732904 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.09907578 |
| 5 | Hepatocellular necrosis (HP:0001404) | 4.06339015 |
| 6 | Increased CSF lactate (HP:0002490) | 3.91562690 |
| 7 | Hepatic necrosis (HP:0002605) | 3.79197265 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.68641263 |
| 9 | Congenital, generalized hypertrichosis (HP:0004540) | 3.66038877 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.55024240 |
| 11 | Pancreatic cysts (HP:0001737) | 3.37690358 |
| 12 | Attenuation of retinal blood vessels (HP:0007843) | 3.23621556 |
| 13 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.20700344 |
| 14 | Nephronophthisis (HP:0000090) | 3.09509680 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 2.98879489 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 2.96999126 |
| 17 | Abnormality of midbrain morphology (HP:0002418) | 2.96999126 |
| 18 | Cerebral edema (HP:0002181) | 2.94203850 |
| 19 | Pancreatic fibrosis (HP:0100732) | 2.92258839 |
| 20 | Increased hepatocellular lipid droplets (HP:0006565) | 2.92044242 |
| 21 | Optic disc pallor (HP:0000543) | 2.89922279 |
| 22 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.86596650 |
| 23 | Absent/shortened dynein arms (HP:0200106) | 2.86596650 |
| 24 | Congenital stationary night blindness (HP:0007642) | 2.83070616 |
| 25 | Lactic acidosis (HP:0003128) | 2.80296037 |
| 26 | Abolished electroretinogram (ERG) (HP:0000550) | 2.78847180 |
| 27 | Increased serum lactate (HP:0002151) | 2.72997827 |
| 28 | Abnormality of the renal medulla (HP:0100957) | 2.68767292 |
| 29 | Abnormality of the renal cortex (HP:0011035) | 2.67122445 |
| 30 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.65593666 |
| 31 | Medial flaring of the eyebrow (HP:0010747) | 2.59107561 |
| 32 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.58910350 |
| 33 | True hermaphroditism (HP:0010459) | 2.56331501 |
| 34 | Increased intramyocellular lipid droplets (HP:0012240) | 2.53954537 |
| 35 | IgG deficiency (HP:0004315) | 2.52046766 |
| 36 | Hyperglycinuria (HP:0003108) | 2.50862694 |
| 37 | Constricted visual fields (HP:0001133) | 2.50562564 |
| 38 | Hyperglycinemia (HP:0002154) | 2.50304071 |
| 39 | Renal cortical cysts (HP:0000803) | 2.46444711 |
| 40 | Methylmalonic acidemia (HP:0002912) | 2.39762284 |
| 41 | Type II lissencephaly (HP:0007260) | 2.37051822 |
| 42 | Decreased central vision (HP:0007663) | 2.37017083 |
| 43 | Sclerocornea (HP:0000647) | 2.34955804 |
| 44 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.33744600 |
| 45 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.33744600 |
| 46 | Respiratory failure (HP:0002878) | 2.31602389 |
| 47 | Abnormality of the prostate (HP:0008775) | 2.31240615 |
| 48 | Renal Fanconi syndrome (HP:0001994) | 2.30364378 |
| 49 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.27778426 |
| 50 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.27778426 |
| 51 | Lethargy (HP:0001254) | 2.24145887 |
| 52 | Increased muscle lipid content (HP:0009058) | 2.23468479 |
| 53 | Stomach cancer (HP:0012126) | 2.22261897 |
| 54 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.19541479 |
| 55 | Hypoproteinemia (HP:0003075) | 2.17492995 |
| 56 | Abnormality of B cell number (HP:0010975) | 2.16757259 |
| 57 | Testicular atrophy (HP:0000029) | 2.16472596 |
| 58 | Hypothermia (HP:0002045) | 2.15165135 |
| 59 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.13245646 |
| 60 | Methylmalonic aciduria (HP:0012120) | 2.08380091 |
| 61 | Polydipsia (HP:0001959) | 2.03434246 |
| 62 | Abnormal drinking behavior (HP:0030082) | 2.03434246 |
| 63 | CNS demyelination (HP:0007305) | 2.01202052 |
| 64 | Delayed CNS myelination (HP:0002188) | 2.00421373 |
| 65 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.00257702 |
| 66 | Abnormality of glycine metabolism (HP:0010895) | 2.00257702 |
| 67 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.96400618 |
| 68 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.95980570 |
| 69 | Hypoplasia of the uterus (HP:0000013) | 1.94502486 |
| 70 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.91747195 |
| 71 | Exercise intolerance (HP:0003546) | 1.91411739 |
| 72 | Colon cancer (HP:0003003) | 1.90077118 |
| 73 | Exertional dyspnea (HP:0002875) | 1.87985447 |
| 74 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.87389140 |
| 75 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.87389140 |
| 76 | Abnormal protein glycosylation (HP:0012346) | 1.87389140 |
| 77 | Abnormal glycosylation (HP:0012345) | 1.87389140 |
| 78 | Asplenia (HP:0001746) | 1.85602144 |
| 79 | Abnormal ciliary motility (HP:0012262) | 1.84365079 |
| 80 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.82643563 |
| 81 | Ketosis (HP:0001946) | 1.81977419 |
| 82 | Bile duct proliferation (HP:0001408) | 1.81287506 |
| 83 | Abnormal biliary tract physiology (HP:0012439) | 1.81287506 |
| 84 | Dicarboxylic aciduria (HP:0003215) | 1.81223090 |
| 85 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.81223090 |
| 86 | Cerebral palsy (HP:0100021) | 1.81076998 |
| 87 | Abnormality of urine glucose concentration (HP:0011016) | 1.80086458 |
| 88 | Glycosuria (HP:0003076) | 1.80086458 |
| 89 | Severe combined immunodeficiency (HP:0004430) | 1.79842490 |
| 90 | Abnormal number of erythroid precursors (HP:0012131) | 1.79535335 |
| 91 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.79126338 |
| 92 | Congenital hepatic fibrosis (HP:0002612) | 1.79040080 |
| 93 | Abnormality of serum amino acid levels (HP:0003112) | 1.78286236 |
| 94 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.77534437 |
| 95 | Absent thumb (HP:0009777) | 1.77103003 |
| 96 | Type I transferrin isoform profile (HP:0003642) | 1.74365936 |
| 97 | Emotional lability (HP:0000712) | 1.72821755 |
| 98 | Cystic liver disease (HP:0006706) | 1.71725413 |
| 99 | Progressive microcephaly (HP:0000253) | 1.71599215 |
| 100 | Leukodystrophy (HP:0002415) | 1.71485742 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 3.27283122 |
| 2 | TLK1 | 2.94886960 |
| 3 | MAP4K2 | 2.69292194 |
| 4 | STK16 | 2.68825258 |
| 5 | NUAK1 | 2.55706614 |
| 6 | FRK | 2.55090814 |
| 7 | BCKDK | 2.54530350 |
| 8 | TAOK3 | 2.45950980 |
| 9 | CDK19 | 2.38991621 |
| 10 | VRK2 | 2.38535378 |
| 11 | TIE1 | 2.36817601 |
| 12 | GRK1 | 2.18322118 |
| 13 | ADRBK2 | 2.09535102 |
| 14 | TXK | 2.09055131 |
| 15 | MAP3K12 | 1.96104219 |
| 16 | KIT | 1.90601613 |
| 17 | BMPR1B | 1.76650184 |
| 18 | NEK1 | 1.72826101 |
| 19 | WNK4 | 1.67231939 |
| 20 | CSNK1G3 | 1.50172504 |
| 21 | TRPM7 | 1.48376643 |
| 22 | CAMKK2 | 1.44221939 |
| 23 | PINK1 | 1.41646484 |
| 24 | EIF2AK3 | 1.37173518 |
| 25 | CSNK1G2 | 1.37062881 |
| 26 | KDR | 1.33655972 |
| 27 | PHKG1 | 1.32728618 |
| 28 | PHKG2 | 1.32728618 |
| 29 | MST4 | 1.32299981 |
| 30 | WNK3 | 1.30831868 |
| 31 | VRK1 | 1.28726173 |
| 32 | MAPKAPK3 | 1.26996088 |
| 33 | CSNK1A1L | 1.26735970 |
| 34 | CSNK1G1 | 1.20313346 |
| 35 | OXSR1 | 1.14908912 |
| 36 | TEC | 1.13134079 |
| 37 | DAPK1 | 1.10016220 |
| 38 | MAP2K7 | 1.08140743 |
| 39 | RPS6KA5 | 1.07247594 |
| 40 | GRK6 | 1.03170835 |
| 41 | IKBKB | 1.01146770 |
| 42 | ITK | 1.00978212 |
| 43 | BMPR2 | 0.99877352 |
| 44 | ERBB3 | 0.95987840 |
| 45 | MKNK1 | 0.91368832 |
| 46 | FLT3 | 0.89543730 |
| 47 | MAP3K4 | 0.87085554 |
| 48 | MAPKAPK5 | 0.86860495 |
| 49 | MYLK | 0.86249316 |
| 50 | INSRR | 0.85876807 |
| 51 | EPHA3 | 0.83934801 |
| 52 | PLK4 | 0.83623734 |
| 53 | DAPK2 | 0.82783372 |
| 54 | NME2 | 0.82681213 |
| 55 | MAPK13 | 0.81421347 |
| 56 | LIMK1 | 0.79353770 |
| 57 | PLK3 | 0.79260425 |
| 58 | PLK2 | 0.76880269 |
| 59 | TRIM28 | 0.74161544 |
| 60 | MAP4K1 | 0.71464525 |
| 61 | MATK | 0.67806357 |
| 62 | GRK7 | 0.67244056 |
| 63 | STK39 | 0.66878755 |
| 64 | ACVR1B | 0.66173816 |
| 65 | SYK | 0.66106013 |
| 66 | MAP2K2 | 0.63873393 |
| 67 | BTK | 0.57467893 |
| 68 | DYRK2 | 0.55380566 |
| 69 | SCYL2 | 0.54304324 |
| 70 | ABL2 | 0.52812835 |
| 71 | FES | 0.52789694 |
| 72 | RPS6KA4 | 0.52230862 |
| 73 | CAMKK1 | 0.49247774 |
| 74 | PASK | 0.49165652 |
| 75 | IGF1R | 0.48425479 |
| 76 | LYN | 0.48123007 |
| 77 | BRSK2 | 0.47638289 |
| 78 | BUB1 | 0.46976834 |
| 79 | CSF1R | 0.45866707 |
| 80 | EIF2AK1 | 0.45559945 |
| 81 | GRK5 | 0.44189459 |
| 82 | CDK8 | 0.43571118 |
| 83 | PRKCE | 0.43548015 |
| 84 | ADRBK1 | 0.42915638 |
| 85 | ATR | 0.42616907 |
| 86 | MUSK | 0.41465945 |
| 87 | PRKCQ | 0.40058334 |
| 88 | FER | 0.39599263 |
| 89 | TAF1 | 0.38106503 |
| 90 | PIK3CA | 0.37819034 |
| 91 | IKBKE | 0.37602793 |
| 92 | DAPK3 | 0.37590966 |
| 93 | CSNK1A1 | 0.37311071 |
| 94 | MAP3K14 | 0.36670636 |
| 95 | LCK | 0.36630625 |
| 96 | ABL1 | 0.35778805 |
| 97 | CSNK2A1 | 0.35702430 |
| 98 | ILK | 0.35417567 |
| 99 | JAK3 | 0.34606189 |
| 100 | CSNK2A2 | 0.33951329 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.67028534 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.54702879 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.13769443 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.96576362 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.64585012 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.56537930 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.49963365 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.38107963 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.37531310 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.34958174 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.22263362 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.21848730 |
| 13 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.06443800 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 2.02841971 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 1.99349749 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.88272394 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.85492729 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79116915 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.78637046 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.68971860 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.57441082 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.56005932 |
| 23 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.55645270 |
| 24 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.50399242 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.46754465 |
| 26 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.45380690 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.44518080 |
| 28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.39847645 |
| 29 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.39546427 |
| 30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.39163517 |
| 31 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.31126438 |
| 32 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.22295678 |
| 33 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.21602566 |
| 34 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.21340150 |
| 35 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.19261260 |
| 36 | Mismatch repair_Homo sapiens_hsa03430 | 1.18778077 |
| 37 | Basal transcription factors_Homo sapiens_hsa03022 | 1.18106714 |
| 38 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.17988542 |
| 39 | Base excision repair_Homo sapiens_hsa03410 | 1.15460390 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.12598380 |
| 41 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.11607744 |
| 42 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.07761179 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 1.05749368 |
| 44 | DNA replication_Homo sapiens_hsa03030 | 1.04267566 |
| 45 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.03252151 |
| 46 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.97696758 |
| 47 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.95875730 |
| 48 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.94025729 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.92867237 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.90608496 |
| 51 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.87675928 |
| 52 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.86889153 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84747947 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.81932136 |
| 55 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.81641457 |
| 56 | Spliceosome_Homo sapiens_hsa03040 | 0.80548746 |
| 57 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.79879711 |
| 58 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.79019759 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.78010848 |
| 60 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.76564396 |
| 61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.75385412 |
| 62 | Viral myocarditis_Homo sapiens_hsa05416 | 0.74262112 |
| 63 | Olfactory transduction_Homo sapiens_hsa04740 | 0.73740607 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72037599 |
| 65 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.69557212 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68976422 |
| 67 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.68953496 |
| 68 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.67386763 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.66782095 |
| 70 | RNA transport_Homo sapiens_hsa03013 | 0.66751354 |
| 71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.66725305 |
| 72 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.62603138 |
| 73 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.62262528 |
| 74 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56699360 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.54919366 |
| 76 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.54301280 |
| 77 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53506693 |
| 78 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.52091915 |
| 79 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.51986162 |
| 80 | Leishmaniasis_Homo sapiens_hsa05140 | 0.51781224 |
| 81 | Retinol metabolism_Homo sapiens_hsa00830 | 0.51416051 |
| 82 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.51317297 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49957407 |
| 84 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.47801475 |
| 85 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.46760633 |
| 86 | Salivary secretion_Homo sapiens_hsa04970 | 0.39946146 |
| 87 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.39881654 |
| 88 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.39186755 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.38306132 |
| 90 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.37769141 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.33089080 |
| 92 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.32912201 |
| 93 | Taste transduction_Homo sapiens_hsa04742 | 0.32846680 |
| 94 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.32110769 |
| 95 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.31512650 |
| 96 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.30898622 |
| 97 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.27876719 |
| 98 | Sulfur relay system_Homo sapiens_hsa04122 | 0.26963309 |
| 99 | Nicotine addiction_Homo sapiens_hsa05033 | 0.25101713 |
| 100 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.23302169 |

