

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 7.94103868 |
| 2 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 7.94103868 |
| 3 | NADH dehydrogenase complex assembly (GO:0010257) | 7.94103868 |
| 4 | mitochondrial calcium ion transport (GO:0006851) | 7.91436417 |
| 5 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 7.11921954 |
| 6 | protein complex biogenesis (GO:0070271) | 6.34293655 |
| 7 | mitochondrial respiratory chain complex assembly (GO:0033108) | 6.07577058 |
| 8 | cellular protein complex localization (GO:0034629) | 5.89847404 |
| 9 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.76762383 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.60276462 |
| 11 | ATP synthesis coupled proton transport (GO:0015986) | 5.60276462 |
| 12 | viral transcription (GO:0019083) | 5.59456085 |
| 13 | translational termination (GO:0006415) | 5.36157240 |
| 14 | neuron fate determination (GO:0048664) | 5.16100206 |
| 15 | ribosomal small subunit assembly (GO:0000028) | 5.10735924 |
| 16 | maturation of SSU-rRNA (GO:0030490) | 4.81007323 |
| 17 | microtubule depolymerization (GO:0007019) | 4.76375766 |
| 18 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.66601093 |
| 19 | cotranslational protein targeting to membrane (GO:0006613) | 4.65347722 |
| 20 | vitamin transmembrane transport (GO:0035461) | 4.64298015 |
| 21 | protein targeting to ER (GO:0045047) | 4.58481918 |
| 22 | hematopoietic stem cell proliferation (GO:0071425) | 4.56295556 |
| 23 | behavioral response to nicotine (GO:0035095) | 4.48795537 |
| 24 | sequestering of actin monomers (GO:0042989) | 4.45113508 |
| 25 | translational elongation (GO:0006414) | 4.43776288 |
| 26 | ribosomal small subunit biogenesis (GO:0042274) | 4.41602824 |
| 27 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.40729224 |
| 28 | cellular protein complex disassembly (GO:0043624) | 4.31860055 |
| 29 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.30797619 |
| 30 | protein localization to endoplasmic reticulum (GO:0070972) | 4.29949101 |
| 31 | protein localization to cilium (GO:0061512) | 4.29561173 |
| 32 | sulfur amino acid catabolic process (GO:0000098) | 4.28731428 |
| 33 | mitochondrial calcium ion homeostasis (GO:0051560) | 4.13781197 |
| 34 | nonmotile primary cilium assembly (GO:0035058) | 4.08591906 |
| 35 | respiratory electron transport chain (GO:0022904) | 3.97943515 |
| 36 | viral life cycle (GO:0019058) | 3.91607194 |
| 37 | electron transport chain (GO:0022900) | 3.91476859 |
| 38 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.91208457 |
| 39 | protein complex localization (GO:0031503) | 3.89600419 |
| 40 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.88483022 |
| 41 | mitotic sister chromatid segregation (GO:0000070) | 3.78848558 |
| 42 | GTP biosynthetic process (GO:0006183) | 3.72307501 |
| 43 | axonemal dynein complex assembly (GO:0070286) | 3.72162619 |
| 44 | protein complex disassembly (GO:0043241) | 3.71866751 |
| 45 | cysteine metabolic process (GO:0006534) | 3.70380870 |
| 46 | regulation of autophagic vacuole assembly (GO:2000785) | 3.54572163 |
| 47 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.49568682 |
| 48 | macromolecular complex disassembly (GO:0032984) | 3.41896596 |
| 49 | chaperone-mediated protein transport (GO:0072321) | 3.41119024 |
| 50 | kinetochore assembly (GO:0051382) | 3.39964150 |
| 51 | translational initiation (GO:0006413) | 3.37681298 |
| 52 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.37050628 |
| 53 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.33881275 |
| 54 | chromatin remodeling at centromere (GO:0031055) | 3.32454935 |
| 55 | epithelial cilium movement (GO:0003351) | 3.26549592 |
| 56 | ATP biosynthetic process (GO:0006754) | 3.21746677 |
| 57 | cilium movement (GO:0003341) | 3.21144095 |
| 58 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.19382864 |
| 59 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.19067409 |
| 60 | UTP biosynthetic process (GO:0006228) | 3.17600831 |
| 61 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.16052272 |
| 62 | sister chromatid segregation (GO:0000819) | 3.11628422 |
| 63 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.10547298 |
| 64 | CENP-A containing nucleosome assembly (GO:0034080) | 3.08277965 |
| 65 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.07260583 |
| 66 | cellular component biogenesis (GO:0044085) | 3.06115052 |
| 67 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.05904200 |
| 68 | hydrogen ion transmembrane transport (GO:1902600) | 3.05707018 |
| 69 | DNA strand elongation (GO:0022616) | 3.03916800 |
| 70 | protein targeting to membrane (GO:0006612) | 3.03615595 |
| 71 | kinetochore organization (GO:0051383) | 3.03400414 |
| 72 | mRNA catabolic process (GO:0006402) | 2.97709231 |
| 73 | midbrain development (GO:0030901) | 2.93873333 |
| 74 | platelet dense granule organization (GO:0060155) | 2.92071430 |
| 75 | regulation of vacuole organization (GO:0044088) | 2.84429214 |
| 76 | UTP metabolic process (GO:0046051) | 2.83004723 |
| 77 | microtubule polymerization or depolymerization (GO:0031109) | 2.80104122 |
| 78 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.79540965 |
| 79 | translation (GO:0006412) | 2.79171248 |
| 80 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.74482557 |
| 81 | intraciliary transport (GO:0042073) | 2.74087662 |
| 82 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.69406229 |
| 83 | proton transport (GO:0015992) | 2.68717332 |
| 84 | homocysteine metabolic process (GO:0050667) | 2.66722161 |
| 85 | serine family amino acid biosynthetic process (GO:0009070) | 2.65993469 |
| 86 | telomere maintenance via recombination (GO:0000722) | 2.63690996 |
| 87 | RNA catabolic process (GO:0006401) | 2.63435387 |
| 88 | hydrogen transport (GO:0006818) | 2.61808174 |
| 89 | termination of RNA polymerase III transcription (GO:0006386) | 2.59063220 |
| 90 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.59063220 |
| 91 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.57720153 |
| 92 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.57614902 |
| 93 | L-fucose catabolic process (GO:0042355) | 2.57230998 |
| 94 | fucose catabolic process (GO:0019317) | 2.57230998 |
| 95 | L-fucose metabolic process (GO:0042354) | 2.57230998 |
| 96 | DNA damage response, detection of DNA damage (GO:0042769) | 2.56912137 |
| 97 | positive regulation of embryonic development (GO:0040019) | 2.54013472 |
| 98 | positive regulation of gastrulation (GO:2000543) | 2.52683145 |
| 99 | mitochondrial transport (GO:0006839) | 2.50975263 |
| 100 | DNA integration (GO:0015074) | 2.50966079 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.87861220 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.88016246 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.07579397 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.65033794 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.24576073 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.11681667 |
| 7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.00086736 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.90870718 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.87305568 |
| 10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.79463435 |
| 11 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.75942378 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.31566110 |
| 13 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.26455420 |
| 14 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.21632164 |
| 15 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.17489411 |
| 16 | EWS_26573619_Chip-Seq_HEK293_Human | 2.14577847 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.13724171 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.11919651 |
| 19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.10656874 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.04203553 |
| 21 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.02615768 |
| 22 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.01982110 |
| 23 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.01020746 |
| 24 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.00902463 |
| 25 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.00463317 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96845375 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.95447811 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.94239312 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.87051143 |
| 30 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.80782489 |
| 31 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.77740658 |
| 32 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.75666149 |
| 33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.74972514 |
| 34 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.74413034 |
| 35 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.71200598 |
| 36 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.68932533 |
| 37 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.67387649 |
| 38 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.63424131 |
| 39 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.54382859 |
| 40 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.47987858 |
| 41 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.44343080 |
| 42 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.44142879 |
| 43 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.38995714 |
| 44 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.38194886 |
| 45 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.38194886 |
| 46 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.37601337 |
| 47 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.35865029 |
| 48 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.34748021 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.34731551 |
| 50 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.32736399 |
| 51 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.30388727 |
| 52 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.23791913 |
| 53 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.22089407 |
| 54 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.22068243 |
| 55 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.20154598 |
| 56 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.18274738 |
| 57 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.18164094 |
| 58 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.17568739 |
| 59 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16729136 |
| 60 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.16330979 |
| 61 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.16163100 |
| 62 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14863545 |
| 63 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.13728447 |
| 64 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.11988116 |
| 65 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.09367315 |
| 66 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.08472680 |
| 67 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.07324402 |
| 68 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.04531965 |
| 69 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.03515137 |
| 70 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.02602877 |
| 71 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.00603219 |
| 72 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.00476313 |
| 73 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.00217674 |
| 74 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.99843981 |
| 75 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.99389159 |
| 76 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.96833704 |
| 77 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.96245268 |
| 78 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.95234349 |
| 79 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.93428875 |
| 80 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.92016972 |
| 81 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.91494192 |
| 82 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.87968442 |
| 83 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.87535619 |
| 84 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.87466879 |
| 85 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.86827658 |
| 86 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.86675563 |
| 87 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.86611397 |
| 88 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.84901822 |
| 89 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.83421677 |
| 90 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.83084026 |
| 91 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.82425435 |
| 92 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.80516271 |
| 93 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.80389597 |
| 94 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.80317972 |
| 95 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.80181276 |
| 96 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.80120178 |
| 97 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.79627520 |
| 98 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.79457788 |
| 99 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.78548568 |
| 100 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.77473175 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.18737724 |
| 2 | MP0010030_abnormal_orbit_morphology | 5.75788542 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.66391535 |
| 4 | MP0000566_synostosis | 3.34307123 |
| 5 | MP0002938_white_spotting | 3.25908591 |
| 6 | MP0003136_yellow_coat_color | 3.19557516 |
| 7 | MP0002653_abnormal_ependyma_morphology | 3.10815763 |
| 8 | MP0001293_anophthalmia | 2.89360937 |
| 9 | MP0004142_abnormal_muscle_tone | 2.74556252 |
| 10 | MP0001346_abnormal_lacrimal_gland | 2.45018309 |
| 11 | MP0001529_abnormal_vocalization | 2.44054859 |
| 12 | MP0002009_preneoplasia | 2.38819709 |
| 13 | MP0002234_abnormal_pharynx_morphology | 2.32264971 |
| 14 | MP0000049_abnormal_middle_ear | 2.31286395 |
| 15 | MP0003283_abnormal_digestive_organ | 2.21936893 |
| 16 | MP0002249_abnormal_larynx_morphology | 2.14822419 |
| 17 | MP0000372_irregular_coat_pigmentation | 2.10478090 |
| 18 | MP0008789_abnormal_olfactory_epithelium | 2.02812135 |
| 19 | MP0003693_abnormal_embryo_hatching | 1.86388064 |
| 20 | MP0003937_abnormal_limbs/digits/tail_de | 1.77491243 |
| 21 | MP0005174_abnormal_tail_pigmentation | 1.59651973 |
| 22 | MP0005645_abnormal_hypothalamus_physiol | 1.57135055 |
| 23 | MP0002697_abnormal_eye_size | 1.55815379 |
| 24 | MP0004742_abnormal_vestibular_system | 1.44062958 |
| 25 | MP0001485_abnormal_pinna_reflex | 1.41385392 |
| 26 | MP0005377_hearing/vestibular/ear_phenot | 1.38974434 |
| 27 | MP0003878_abnormal_ear_physiology | 1.38974434 |
| 28 | MP0005394_taste/olfaction_phenotype | 1.37850707 |
| 29 | MP0005499_abnormal_olfactory_system | 1.37850707 |
| 30 | MP0009053_abnormal_anal_canal | 1.37707833 |
| 31 | MP0003806_abnormal_nucleotide_metabolis | 1.33421931 |
| 32 | MP0002233_abnormal_nose_morphology | 1.32902526 |
| 33 | MP0006035_abnormal_mitochondrial_morpho | 1.31948668 |
| 34 | MP0006276_abnormal_autonomic_nervous | 1.30544573 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.28429900 |
| 36 | MP0001764_abnormal_homeostasis | 1.26491097 |
| 37 | MP0002102_abnormal_ear_morphology | 1.24985577 |
| 38 | MP0003880_abnormal_central_pattern | 1.24870343 |
| 39 | MP0003938_abnormal_ear_development | 1.24275930 |
| 40 | MP0000026_abnormal_inner_ear | 1.24135254 |
| 41 | MP0001286_abnormal_eye_development | 1.24096554 |
| 42 | MP0002822_catalepsy | 1.23961639 |
| 43 | MP0005253_abnormal_eye_physiology | 1.18941206 |
| 44 | MP0005391_vision/eye_phenotype | 1.14204738 |
| 45 | MP0003718_maternal_effect | 1.13348731 |
| 46 | MP0003942_abnormal_urinary_system | 1.12452666 |
| 47 | MP0004885_abnormal_endolymph | 1.12343330 |
| 48 | MP0004133_heterotaxia | 1.12117238 |
| 49 | MP0009250_abnormal_appendicular_skeleto | 1.11266385 |
| 50 | MP0002277_abnormal_respiratory_mucosa | 1.11008105 |
| 51 | MP0003755_abnormal_palate_morphology | 1.09213023 |
| 52 | MP0004043_abnormal_pH_regulation | 1.08399981 |
| 53 | MP0002095_abnormal_skin_pigmentation | 1.05584533 |
| 54 | MP0008875_abnormal_xenobiotic_pharmacok | 1.04217641 |
| 55 | MP0000631_abnormal_neuroendocrine_gland | 1.01654689 |
| 56 | MP0005248_abnormal_Harderian_gland | 1.01568865 |
| 57 | MP0009046_muscle_twitch | 1.00804299 |
| 58 | MP0005409_darkened_coat_color | 0.98349072 |
| 59 | MP0005408_hypopigmentation | 0.97662067 |
| 60 | MP0001873_stomach_inflammation | 0.96406436 |
| 61 | MP0005195_abnormal_posterior_eye | 0.94744804 |
| 62 | MP0000778_abnormal_nervous_system | 0.94026341 |
| 63 | MP0003315_abnormal_perineum_morphology | 0.93677716 |
| 64 | MP0001905_abnormal_dopamine_level | 0.93443666 |
| 65 | MP0008877_abnormal_DNA_methylation | 0.92120918 |
| 66 | MP0003567_abnormal_fetal_cardiomyocyte | 0.91507982 |
| 67 | MP0001348_abnormal_lacrimal_gland | 0.89434193 |
| 68 | MP0000647_abnormal_sebaceous_gland | 0.88221905 |
| 69 | MP0002092_abnormal_eye_morphology | 0.85160844 |
| 70 | MP0003959_abnormal_lean_body | 0.84882033 |
| 71 | MP0002736_abnormal_nociception_after | 0.82321348 |
| 72 | MP0001324_abnormal_eye_pigmentation | 0.81211141 |
| 73 | MP0002909_abnormal_adrenal_gland | 0.78093212 |
| 74 | MP0003011_delayed_dark_adaptation | 0.77153314 |
| 75 | MP0002752_abnormal_somatic_nervous | 0.76702534 |
| 76 | MP0002282_abnormal_trachea_morphology | 0.73616508 |
| 77 | MP0001340_abnormal_eyelid_morphology | 0.72685007 |
| 78 | MP0003111_abnormal_nucleus_morphology | 0.71834787 |
| 79 | MP0005646_abnormal_pituitary_gland | 0.71040772 |
| 80 | MP0009745_abnormal_behavioral_response | 0.69818891 |
| 81 | MP0004145_abnormal_muscle_electrophysio | 0.68708003 |
| 82 | MP0003861_abnormal_nervous_system | 0.68686674 |
| 83 | MP0002210_abnormal_sex_determination | 0.66994897 |
| 84 | MP0002876_abnormal_thyroid_physiology | 0.66683258 |
| 85 | MP0003119_abnormal_digestive_system | 0.66523893 |
| 86 | MP0008872_abnormal_physiological_respon | 0.64839762 |
| 87 | MP0002109_abnormal_limb_morphology | 0.63017520 |
| 88 | MP0005187_abnormal_penis_morphology | 0.63013768 |
| 89 | MP0001727_abnormal_embryo_implantation | 0.61596362 |
| 90 | MP0001663_abnormal_digestive_system | 0.61459449 |
| 91 | MP0002116_abnormal_craniofacial_bone | 0.61222549 |
| 92 | MP0003890_abnormal_embryonic-extraembry | 0.61093417 |
| 93 | MP0001186_pigmentation_phenotype | 0.60545263 |
| 94 | MP0002075_abnormal_coat/hair_pigmentati | 0.60304198 |
| 95 | MP0002111_abnormal_tail_morphology | 0.58855332 |
| 96 | MP0003122_maternal_imprinting | 0.58237463 |
| 97 | MP0010094_abnormal_chromosome_stability | 0.57907485 |
| 98 | MP0001929_abnormal_gametogenesis | 0.55451269 |
| 99 | MP0002572_abnormal_emotion/affect_behav | 0.54462907 |
| 100 | MP0003698_abnormal_male_reproductive | 0.53800661 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 4.67265335 |
| 2 | Hypoplasia of the pons (HP:0012110) | 4.48203298 |
| 3 | Abnormality of the pons (HP:0007361) | 4.16732765 |
| 4 | Missing ribs (HP:0000921) | 3.91507119 |
| 5 | Pheochromocytoma (HP:0002666) | 3.81334123 |
| 6 | 11 pairs of ribs (HP:0000878) | 3.78350759 |
| 7 | Concave nail (HP:0001598) | 3.68394358 |
| 8 | Abnormality of alanine metabolism (HP:0010916) | 3.65253480 |
| 9 | Hyperalaninemia (HP:0003348) | 3.65253480 |
| 10 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.65253480 |
| 11 | Pancreatic cysts (HP:0001737) | 3.58381952 |
| 12 | Mesomelia (HP:0003027) | 3.51335125 |
| 13 | Rib fusion (HP:0000902) | 3.50417301 |
| 14 | Abnormal ciliary motility (HP:0012262) | 3.48018976 |
| 15 | Abnormal number of erythroid precursors (HP:0012131) | 3.29746187 |
| 16 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.28348531 |
| 17 | Short 4th metacarpal (HP:0010044) | 3.28348531 |
| 18 | Abnormality of the 4th metacarpal (HP:0010012) | 3.25922457 |
| 19 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.25084995 |
| 20 | Acute encephalopathy (HP:0006846) | 3.22000405 |
| 21 | Septo-optic dysplasia (HP:0100842) | 3.19779002 |
| 22 | Neuroendocrine neoplasm (HP:0100634) | 3.14565068 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 3.12505060 |
| 24 | Molar tooth sign on MRI (HP:0002419) | 3.12505060 |
| 25 | Anophthalmia (HP:0000528) | 3.10171584 |
| 26 | Confusion (HP:0001289) | 3.02549554 |
| 27 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.02535601 |
| 28 | Chorioretinal atrophy (HP:0000533) | 3.01596239 |
| 29 | Short middle phalanx of the 5th finger (HP:0004220) | 2.94726919 |
| 30 | Sclerocornea (HP:0000647) | 2.88203575 |
| 31 | Acute necrotizing encephalopathy (HP:0006965) | 2.85446386 |
| 32 | Macrocytic anemia (HP:0001972) | 2.81982730 |
| 33 | Mitochondrial inheritance (HP:0001427) | 2.78700088 |
| 34 | Cutaneous finger syndactyly (HP:0010554) | 2.70765087 |
| 35 | Reticulocytopenia (HP:0001896) | 2.61898569 |
| 36 | Pancreatic fibrosis (HP:0100732) | 2.60789569 |
| 37 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.58696329 |
| 38 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.58117897 |
| 39 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.49696302 |
| 40 | Medial flaring of the eyebrow (HP:0010747) | 2.45253684 |
| 41 | 3-Methylglutaconic aciduria (HP:0003535) | 2.38874505 |
| 42 | Congenital, generalized hypertrichosis (HP:0004540) | 2.38594725 |
| 43 | Type I transferrin isoform profile (HP:0003642) | 2.33626775 |
| 44 | Maternal diabetes (HP:0009800) | 2.32702723 |
| 45 | True hermaphroditism (HP:0010459) | 2.32509075 |
| 46 | Bifid tongue (HP:0010297) | 2.31241203 |
| 47 | Hepatocellular necrosis (HP:0001404) | 2.29187098 |
| 48 | Congenital stationary night blindness (HP:0007642) | 2.29096199 |
| 49 | Type II lissencephaly (HP:0007260) | 2.26130130 |
| 50 | Increased CSF lactate (HP:0002490) | 2.22655002 |
| 51 | Pendular nystagmus (HP:0012043) | 2.21624492 |
| 52 | Poor coordination (HP:0002370) | 2.20571949 |
| 53 | Vaginal atresia (HP:0000148) | 2.16981762 |
| 54 | High anterior hairline (HP:0009890) | 2.15060054 |
| 55 | Mutism (HP:0002300) | 2.14251286 |
| 56 | Abnormality of the parietal bone (HP:0002696) | 2.14028669 |
| 57 | Abnormality of abdominal situs (HP:0011620) | 2.13487780 |
| 58 | Abdominal situs inversus (HP:0003363) | 2.13487780 |
| 59 | Cutaneous syndactyly (HP:0012725) | 2.12315094 |
| 60 | Progressive macrocephaly (HP:0004481) | 2.11622522 |
| 61 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.10995907 |
| 62 | Congenital primary aphakia (HP:0007707) | 2.10219021 |
| 63 | Nephronophthisis (HP:0000090) | 2.07665781 |
| 64 | Optic disc pallor (HP:0000543) | 2.07533970 |
| 65 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.06985060 |
| 66 | Gait imbalance (HP:0002141) | 2.06872992 |
| 67 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.06852363 |
| 68 | Anencephaly (HP:0002323) | 2.06539288 |
| 69 | Genital tract atresia (HP:0001827) | 2.02018021 |
| 70 | Brushfield spots (HP:0001088) | 1.99054443 |
| 71 | Abnormal lung lobation (HP:0002101) | 1.97418358 |
| 72 | Hepatic necrosis (HP:0002605) | 1.95802684 |
| 73 | Absent septum pellucidum (HP:0001331) | 1.95640296 |
| 74 | Cerebral edema (HP:0002181) | 1.95573183 |
| 75 | Focal motor seizures (HP:0011153) | 1.91152312 |
| 76 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.91003249 |
| 77 | Retinal dysplasia (HP:0007973) | 1.90465427 |
| 78 | Chronic hepatic failure (HP:0100626) | 1.88562854 |
| 79 | Bilateral microphthalmos (HP:0007633) | 1.88428067 |
| 80 | Partial duplication of the phalanx of hand (HP:0009999) | 1.86348644 |
| 81 | Paraparesis (HP:0002385) | 1.86307022 |
| 82 | Nephrogenic diabetes insipidus (HP:0009806) | 1.84940997 |
| 83 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.83983244 |
| 84 | Birth length less than 3rd percentile (HP:0003561) | 1.83864833 |
| 85 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.83676760 |
| 86 | Hyperglycinemia (HP:0002154) | 1.82277624 |
| 87 | Abnormality of the diencephalon (HP:0010662) | 1.81959790 |
| 88 | Multicystic kidney dysplasia (HP:0000003) | 1.80919454 |
| 89 | Abolished electroretinogram (ERG) (HP:0000550) | 1.80196129 |
| 90 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.79753035 |
| 91 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.79753035 |
| 92 | Partial agenesis of the corpus callosum (HP:0001338) | 1.79504515 |
| 93 | Lipid accumulation in hepatocytes (HP:0006561) | 1.77781953 |
| 94 | Lactic acidosis (HP:0003128) | 1.77641996 |
| 95 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.76573039 |
| 96 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.76573039 |
| 97 | Occipital encephalocele (HP:0002085) | 1.76391894 |
| 98 | Lissencephaly (HP:0001339) | 1.76088103 |
| 99 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.74098876 |
| 100 | Abnormal glycosylation (HP:0012345) | 1.74098876 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 7.99509780 |
| 2 | BUB1 | 3.68086016 |
| 3 | WEE1 | 3.57387319 |
| 4 | VRK1 | 3.33181929 |
| 5 | INSRR | 3.24940666 |
| 6 | TAF1 | 2.75502598 |
| 7 | BLK | 2.68569532 |
| 8 | NEK2 | 2.44882972 |
| 9 | NME1 | 2.23768731 |
| 10 | EPHB2 | 2.20707968 |
| 11 | STK3 | 2.17246896 |
| 12 | EIF2AK3 | 1.99372785 |
| 13 | YES1 | 1.89864991 |
| 14 | CCNB1 | 1.85982604 |
| 15 | TLK1 | 1.81887481 |
| 16 | BRSK2 | 1.81525356 |
| 17 | BCKDK | 1.62301391 |
| 18 | CHEK2 | 1.57764177 |
| 19 | KIT | 1.39007423 |
| 20 | STK16 | 1.38955078 |
| 21 | MAP2K7 | 1.38007202 |
| 22 | MAP3K12 | 1.36941057 |
| 23 | EIF2AK2 | 1.28076870 |
| 24 | TYRO3 | 1.23340601 |
| 25 | MAPKAPK5 | 1.15633990 |
| 26 | MAP3K4 | 1.15468660 |
| 27 | PNCK | 1.14171164 |
| 28 | PLK4 | 1.13296538 |
| 29 | MAP3K9 | 1.13094204 |
| 30 | ZAK | 1.11466611 |
| 31 | CDC7 | 1.09627682 |
| 32 | GRK1 | 1.09435248 |
| 33 | NUAK1 | 1.08067859 |
| 34 | MAPKAPK3 | 1.05982326 |
| 35 | PDGFRB | 1.05619696 |
| 36 | CLK1 | 1.04343384 |
| 37 | CAMK1 | 1.02480783 |
| 38 | ADRBK2 | 0.99217619 |
| 39 | SYK | 0.97915316 |
| 40 | BMPR1B | 0.97043150 |
| 41 | WNK3 | 0.95934111 |
| 42 | EPHA4 | 0.91794390 |
| 43 | DYRK2 | 0.91386961 |
| 44 | CAMK4 | 0.89812612 |
| 45 | MAP2K4 | 0.89322530 |
| 46 | PIM1 | 0.85955284 |
| 47 | PLK3 | 0.84537653 |
| 48 | RPS6KA6 | 0.82977188 |
| 49 | UHMK1 | 0.82366320 |
| 50 | WNK4 | 0.82163914 |
| 51 | RPS6KA5 | 0.75286193 |
| 52 | PLK1 | 0.71776787 |
| 53 | TAOK2 | 0.69449319 |
| 54 | BRSK1 | 0.68472665 |
| 55 | ATR | 0.65719749 |
| 56 | DYRK1B | 0.65060099 |
| 57 | TAOK3 | 0.64727349 |
| 58 | STK24 | 0.59727597 |
| 59 | RPS6KL1 | 0.57125469 |
| 60 | RPS6KC1 | 0.57125469 |
| 61 | LRRK2 | 0.57065350 |
| 62 | SIK1 | 0.56227955 |
| 63 | PRKCG | 0.54541809 |
| 64 | CDK7 | 0.53213119 |
| 65 | MAP3K11 | 0.48614943 |
| 66 | AURKA | 0.48114437 |
| 67 | MOS | 0.47774713 |
| 68 | CASK | 0.47013268 |
| 69 | CDK3 | 0.45736377 |
| 70 | MAP3K8 | 0.45559269 |
| 71 | CSNK2A1 | 0.45046139 |
| 72 | MKNK1 | 0.43434346 |
| 73 | CSNK1A1 | 0.40831984 |
| 74 | MAPK15 | 0.40720218 |
| 75 | AURKB | 0.40490716 |
| 76 | FES | 0.39018473 |
| 77 | ERBB3 | 0.38805954 |
| 78 | PRKCH | 0.38449652 |
| 79 | MAP3K10 | 0.37504848 |
| 80 | FRK | 0.35534970 |
| 81 | PRKCZ | 0.35481790 |
| 82 | PINK1 | 0.35057155 |
| 83 | DYRK3 | 0.35050033 |
| 84 | HIPK2 | 0.32678959 |
| 85 | CSNK2A2 | 0.32387006 |
| 86 | MAP4K2 | 0.30393800 |
| 87 | TXK | 0.30310743 |
| 88 | TNIK | 0.28676983 |
| 89 | DAPK3 | 0.22993418 |
| 90 | TTK | 0.22163780 |
| 91 | INSR | 0.21623366 |
| 92 | TRPM7 | 0.21040269 |
| 93 | NTRK2 | 0.20689224 |
| 94 | MAPK7 | 0.20040535 |
| 95 | PTK2B | 0.19228831 |
| 96 | MAP3K7 | 0.18726777 |
| 97 | CDK1 | 0.18611512 |
| 98 | NTRK3 | 0.16896832 |
| 99 | CAMK2A | 0.16579897 |
| 100 | ERN1 | 0.16542472 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.90430448 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.16368149 |
| 3 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 3.70764938 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.47002935 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 3.07151138 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.82960109 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.78069396 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.54225890 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.46030062 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.41480468 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.40323611 |
| 12 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.30573863 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.24569382 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 2.21738861 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.21445945 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.15783491 |
| 17 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 2.10044045 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.04622561 |
| 19 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.97923417 |
| 20 | Protein export_Homo sapiens_hsa03060 | 1.91564969 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.81551161 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.74413353 |
| 23 | Sulfur relay system_Homo sapiens_hsa04122 | 1.70997415 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.61543967 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.51708081 |
| 26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.51263509 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.36143469 |
| 28 | Spliceosome_Homo sapiens_hsa03040 | 1.31036909 |
| 29 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.29595043 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.23382482 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.18086837 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.09619649 |
| 33 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.05447587 |
| 34 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.00933324 |
| 35 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.99274412 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.98286838 |
| 37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.98015108 |
| 38 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.97794515 |
| 39 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.96994387 |
| 40 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.95923611 |
| 41 | Nicotine addiction_Homo sapiens_hsa05033 | 0.87654135 |
| 42 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.86361989 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.85742390 |
| 44 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.85503637 |
| 45 | Alcoholism_Homo sapiens_hsa05034 | 0.84856824 |
| 46 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.82810396 |
| 47 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.82486636 |
| 48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.80996794 |
| 49 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.79795473 |
| 50 | Cell cycle_Homo sapiens_hsa04110 | 0.79758593 |
| 51 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.77210433 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.74756413 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74631126 |
| 54 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73413656 |
| 55 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.72106390 |
| 56 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.67243434 |
| 57 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.67042592 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.64493292 |
| 59 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.63493815 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63372081 |
| 61 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.63280463 |
| 62 | RNA transport_Homo sapiens_hsa03013 | 0.57879953 |
| 63 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.57108949 |
| 64 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.52847386 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52167992 |
| 66 | Melanogenesis_Homo sapiens_hsa04916 | 0.50571486 |
| 67 | Taste transduction_Homo sapiens_hsa04742 | 0.46997768 |
| 68 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.44072998 |
| 69 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.44013118 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.42013657 |
| 71 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.41425852 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40049993 |
| 73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.37653238 |
| 74 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.37186276 |
| 75 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.35332544 |
| 76 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.33780064 |
| 77 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.32498625 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.31852669 |
| 79 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.27308224 |
| 80 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.24506692 |
| 81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.23480186 |
| 82 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.23236179 |
| 83 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.22834426 |
| 84 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.21801233 |
| 85 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.19616271 |
| 86 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.18760991 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.17886979 |
| 88 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.17697191 |
| 89 | Mineral absorption_Homo sapiens_hsa04978 | 0.16581941 |
| 90 | Axon guidance_Homo sapiens_hsa04360 | 0.16453030 |
| 91 | Olfactory transduction_Homo sapiens_hsa04740 | 0.12424108 |
| 92 | Lysine degradation_Homo sapiens_hsa00310 | 0.10867656 |
| 93 | HTLV-I infection_Homo sapiens_hsa05166 | 0.10420040 |
| 94 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.09681815 |
| 95 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.09476777 |
| 96 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.09126632 |
| 97 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.08953851 |
| 98 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.06808846 |
| 99 | Cocaine addiction_Homo sapiens_hsa05030 | 0.06586227 |
| 100 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.05899982 |

