SNRPF

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.99620747
2ribosomal small subunit assembly (GO:0000028)6.93716475
3viral transcription (GO:0019083)6.74338562
4translational termination (GO:0006415)6.52091195
5DNA deamination (GO:0045006)6.45017695
6ribosomal small subunit biogenesis (GO:0042274)6.23096491
7ATP synthesis coupled proton transport (GO:0015986)6.14990782
8energy coupled proton transport, down electrochemical gradient (GO:0015985)6.14990782
9chaperone-mediated protein transport (GO:0072321)5.91014062
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.75258044
11translational elongation (GO:0006414)5.69284800
12maturation of SSU-rRNA (GO:0030490)5.63032202
13cotranslational protein targeting to membrane (GO:0006613)5.62709039
14protein targeting to ER (GO:0045047)5.60989978
15establishment of protein localization to mitochondrial membrane (GO:0090151)5.57923938
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.34025911
17establishment of protein localization to endoplasmic reticulum (GO:0072599)5.32774141
18protein localization to endoplasmic reticulum (GO:0070972)5.28843958
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.15338979
20cellular protein complex disassembly (GO:0043624)5.12159691
21ribosomal large subunit biogenesis (GO:0042273)5.11926883
22translational initiation (GO:0006413)5.11118635
23viral life cycle (GO:0019058)5.07884166
24respiratory electron transport chain (GO:0022904)5.00063889
25electron transport chain (GO:0022900)4.88962212
26telomere maintenance via semi-conservative replication (GO:0032201)4.76360107
27DNA strand elongation involved in DNA replication (GO:0006271)4.66805094
28protein complex disassembly (GO:0043241)4.54338138
29DNA strand elongation (GO:0022616)4.45505015
30ribonucleoprotein complex biogenesis (GO:0022613)4.38347808
31macromolecular complex disassembly (GO:0032984)4.29731210
32regulation of mitochondrial translation (GO:0070129)4.27577104
33DNA replication initiation (GO:0006270)4.23840724
34translation (GO:0006412)4.20875852
35protein complex biogenesis (GO:0070271)4.20307339
36telomere maintenance via recombination (GO:0000722)4.15112689
37deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.14671919
38protein neddylation (GO:0045116)4.13100628
39mitochondrial respiratory chain complex assembly (GO:0033108)4.12874829
40nuclear-transcribed mRNA catabolic process (GO:0000956)4.02682083
41mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.01697677
42mitochondrial respiratory chain complex I assembly (GO:0032981)4.01697677
43NADH dehydrogenase complex assembly (GO:0010257)4.01697677
44proteasome assembly (GO:0043248)4.00201310
45DNA replication checkpoint (GO:0000076)3.96346974
46rRNA processing (GO:0006364)3.84039091
47CENP-A containing nucleosome assembly (GO:0034080)3.83936041
48mitotic recombination (GO:0006312)3.83483773
49mRNA catabolic process (GO:0006402)3.83159937
50chromatin remodeling at centromere (GO:0031055)3.78024439
51pseudouridine synthesis (GO:0001522)3.76731600
52telomere maintenance via telomere lengthening (GO:0010833)3.72147365
53spliceosomal complex assembly (GO:0000245)3.71245764
54formation of translation preinitiation complex (GO:0001731)3.69748725
55rRNA metabolic process (GO:0016072)3.69623184
56RNA catabolic process (GO:0006401)3.65623241
57exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.65200641
58* spliceosomal snRNP assembly (GO:0000387)3.63647177
59transcription elongation from RNA polymerase III promoter (GO:0006385)3.62922057
60termination of RNA polymerase III transcription (GO:0006386)3.62922057
61protein targeting to membrane (GO:0006612)3.62859584
62protein targeting to mitochondrion (GO:0006626)3.62233478
63establishment of integrated proviral latency (GO:0075713)3.55609820
64DNA damage response, detection of DNA damage (GO:0042769)3.52345225
65kinetochore organization (GO:0051383)3.52064478
66kinetochore assembly (GO:0051382)3.49105185
67cellular component biogenesis (GO:0044085)3.49021651
68nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.49016995
69nucleotide-excision repair, DNA gap filling (GO:0006297)3.45980121
70DNA unwinding involved in DNA replication (GO:0006268)3.44182834
71ribosome biogenesis (GO:0042254)3.44097170
72inner mitochondrial membrane organization (GO:0007007)3.42500975
73establishment of protein localization to mitochondrion (GO:0072655)3.39667238
74DNA replication-independent nucleosome organization (GO:0034724)3.37888345
75DNA replication-independent nucleosome assembly (GO:0006336)3.37888345
76protein localization to mitochondrion (GO:0070585)3.37229732
77ATP biosynthetic process (GO:0006754)3.36522020
78transcription-coupled nucleotide-excision repair (GO:0006283)3.31917451
79respiratory chain complex IV assembly (GO:0008535)3.29692613
80regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.22650848
81regulation of mitotic spindle checkpoint (GO:1903504)3.22650848
82negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.21537872
83mitotic metaphase plate congression (GO:0007080)3.19501472
84cytochrome complex assembly (GO:0017004)3.17705970
85purine nucleoside triphosphate biosynthetic process (GO:0009145)3.17072063
86purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.16746227
87negative regulation of RNA splicing (GO:0033119)3.13711965
88oxidative phosphorylation (GO:0006119)3.12433547
89deoxyribonucleotide biosynthetic process (GO:0009263)3.11279990
90viral mRNA export from host cell nucleus (GO:0046784)3.11238218
91rRNA modification (GO:0000154)3.10553715
92regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.09466046
93nucleobase biosynthetic process (GO:0046112)3.05880269
94peptidyl-histidine modification (GO:0018202)3.05117648
95pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.04095910
96anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.02344053
97hydrogen ion transmembrane transport (GO:1902600)3.02214649
98regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.00586389
99histone exchange (GO:0043486)2.97511200
100ribonucleoside triphosphate biosynthetic process (GO:0009201)2.96384738
101negative regulation of ligase activity (GO:0051352)2.96016760
102negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.96016760
103positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.95956336
1047-methylguanosine mRNA capping (GO:0006370)2.93200441
105DNA replication-dependent nucleosome assembly (GO:0006335)2.92645668
106DNA replication-dependent nucleosome organization (GO:0034723)2.92645668
107protein localization to kinetochore (GO:0034501)2.92502581
108pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.91925987
109intracellular protein transmembrane import (GO:0044743)2.91687040
110ribosome assembly (GO:0042255)2.91290464
1112-deoxyribonucleotide biosynthetic process (GO:0009265)2.91077122
112deoxyribose phosphate biosynthetic process (GO:0046385)2.91077122
113RNA capping (GO:0036260)2.89882943
1147-methylguanosine RNA capping (GO:0009452)2.89882943
115RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.89325847
116tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.89325847
117rRNA methylation (GO:0031167)2.89146274
118ncRNA processing (GO:0034470)2.89096698
119folic acid-containing compound biosynthetic process (GO:0009396)2.84664113
120negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.83770164
121* termination of RNA polymerase II transcription (GO:0006369)2.83685786
122pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.83487607
123* RNA splicing, via transesterification reactions (GO:0000375)2.82790131
124purine nucleobase biosynthetic process (GO:0009113)2.82049254
125* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.81279847
126* mRNA splicing, via spliceosome (GO:0000398)2.81279847
127regulation of double-strand break repair via homologous recombination (GO:0010569)2.81233020
128* DNA-templated transcription, termination (GO:0006353)2.81054646
129cell cycle G1/S phase transition (GO:0044843)2.78870910
130G1/S transition of mitotic cell cycle (GO:0000082)2.78870910
131DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.78766267
132metaphase plate congression (GO:0051310)2.77921206
133establishment of viral latency (GO:0019043)2.77313089
134regulation of nuclear cell cycle DNA replication (GO:0033262)2.76516003
135protein localization to chromosome, centromeric region (GO:0071459)2.76414684

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.34841213
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.73587685
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.03267991
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.64883233
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.43140767
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.43028895
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.34065727
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.26661303
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.19883215
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.16645184
11MYC_18358816_ChIP-ChIP_MESCs_Mouse3.13755446
12MYC_19079543_ChIP-ChIP_MESCs_Mouse3.13731396
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.96060298
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.94585044
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.94163686
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.90614787
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.87435993
18XRN2_22483619_ChIP-Seq_HELA_Human2.63690628
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.54537384
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.50199759
21* VDR_23849224_ChIP-Seq_CD4+_Human2.49109558
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.48670026
23* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.25947328
24NELFA_20434984_ChIP-Seq_ESCs_Mouse2.24822671
25DCP1A_22483619_ChIP-Seq_HELA_Human2.20339981
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.17501099
27E2F1_18555785_ChIP-Seq_MESCs_Mouse2.14890975
28TTF2_22483619_ChIP-Seq_HELA_Human2.12973085
29FOXP3_21729870_ChIP-Seq_TREG_Human2.10191859
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.01825844
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.01365006
32THAP11_20581084_ChIP-Seq_MESCs_Mouse1.96394015
33GABP_19822575_ChIP-Seq_HepG2_Human1.96351895
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.85798124
35ELK1_19687146_ChIP-ChIP_HELA_Human1.85066729
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.80017006
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.74547902
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.74089726
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.73186723
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.69183366
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.67710250
42SRF_21415370_ChIP-Seq_HL-1_Mouse1.67531881
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.66836183
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.59185940
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.57578121
46ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.57566834
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.55565717
48AR_21909140_ChIP-Seq_LNCAP_Human1.51955099
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.51492590
50CIITA_25753668_ChIP-Seq_RAJI_Human1.50678144
51ERG_20887958_ChIP-Seq_HPC-7_Mouse1.49786819
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47934867
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.46918969
54E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.45347202
55* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.43645986
56EWS_26573619_Chip-Seq_HEK293_Human1.41563337
57YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41504140
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.40518559
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37820876
60HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.36420503
61SOX2_16153702_ChIP-ChIP_HESCs_Human1.36237100
62MYC_22102868_ChIP-Seq_BL_Human1.34797593
63NANOG_16153702_ChIP-ChIP_HESCs_Human1.31197969
64SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.30046551
65MYC_18940864_ChIP-ChIP_HL60_Human1.28650665
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.28237740
67KDM5A_27292631_Chip-Seq_BREAST_Human1.26993961
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.23404639
69FUS_26573619_Chip-Seq_HEK293_Human1.22842883
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.19489314
71ELK1_22589737_ChIP-Seq_MCF10A_Human1.19487909
72VDR_21846776_ChIP-Seq_THP-1_Human1.19328042
73KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.15759593
74CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.13999491
75SPI1_23547873_ChIP-Seq_NB4_Human1.12025169
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.11715379
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10880259
78GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.10649881
79* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.10127284
80ZNF274_21170338_ChIP-Seq_K562_Hela1.10104571
81VDR_22108803_ChIP-Seq_LS180_Human1.09536125
82TP63_19390658_ChIP-ChIP_HaCaT_Human1.08116531
83* HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.07240344
84DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04270211
85BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.00263063
86* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99697955
87EGR1_19374776_ChIP-ChIP_THP-1_Human0.98118736
88PADI4_21655091_ChIP-ChIP_MCF-7_Human0.98069615
89KLF4_18555785_ChIP-Seq_MESCs_Mouse0.97483235
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96671797
91TFEB_21752829_ChIP-Seq_HELA_Human0.96006592
92STAT3_1855785_ChIP-Seq_MESCs_Mouse0.92465933
93SOX2_18555785_ChIP-Seq_MESCs_Mouse0.91660856
94IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.91492531
95HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90190382
96TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88014666
97CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87449696
98CTCF_18555785_ChIP-Seq_MESCs_Mouse0.84171687
99SALL1_21062744_ChIP-ChIP_HESCs_Human0.83741684
100SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82421190
101FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82005206
102RBPJ_22232070_ChIP-Seq_NCS_Mouse0.81835211
103SOX17_20123909_ChIP-Seq_XEN_Mouse0.81259120
104SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.80474756
105KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.80241964
106* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.76348072
107NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.76047912
108SOX2_18692474_ChIP-Seq_MEFs_Mouse0.75933901
109DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.75517787
110GATA1_22383799_ChIP-Seq_G1ME_Mouse0.75447371
111* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.75321646
112ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.74426570
113* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.73817828
114IGF1R_20145208_ChIP-Seq_DFB_Human0.73633509
115POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.73608662
116KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.72808884
117IRF1_19129219_ChIP-ChIP_H3396_Human0.72526471
118KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.72517241
119KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.72517241
120KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.72517241
121SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.71983863
122CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71146564
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.70994178
124FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.70443709
125TP53_22573176_ChIP-Seq_HFKS_Human0.70251310
126NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.69984581

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.51298971
2MP0004957_abnormal_blastocyst_morpholog4.27060334
3MP0010094_abnormal_chromosome_stability4.06237995
4MP0003111_abnormal_nucleus_morphology3.82706386
5MP0003077_abnormal_cell_cycle3.65950037
6MP0009379_abnormal_foot_pigmentation3.52217889
7MP0008057_abnormal_DNA_replication3.34251906
8MP0008058_abnormal_DNA_repair3.21905956
9MP0008007_abnormal_cellular_replicative2.84010696
10MP0008932_abnormal_embryonic_tissue2.77487384
11MP0002396_abnormal_hematopoietic_system2.55654449
12MP0003786_premature_aging2.16449823
13MP0000490_abnormal_crypts_of2.15600720
14MP0001529_abnormal_vocalization1.99944176
15MP0006292_abnormal_olfactory_placode1.81842982
16MP0006072_abnormal_retinal_apoptosis1.80606974
17MP0003763_abnormal_thymus_physiology1.79478594
18MP0000350_abnormal_cell_proliferation1.78036211
19MP0009333_abnormal_splenocyte_physiolog1.75157991
20MP0002132_abnormal_respiratory_system1.67583608
21MP0009697_abnormal_copulation1.64898612
22MP0006054_spinal_hemorrhage1.60300365
23MP0003123_paternal_imprinting1.59778802
24MP0005174_abnormal_tail_pigmentation1.56439102
25MP0001730_embryonic_growth_arrest1.54413738
26MP0005397_hematopoietic_system_phenotyp1.50447434
27MP0001545_abnormal_hematopoietic_system1.50447434
28MP0004808_abnormal_hematopoietic_stem1.50365779
29MP0003937_abnormal_limbs/digits/tail_de1.49228085
30MP0000313_abnormal_cell_death1.48404936
31MP0003890_abnormal_embryonic-extraembry1.48180540
32MP0003136_yellow_coat_color1.47949823
33MP0002019_abnormal_tumor_incidence1.44877359
34MP0008877_abnormal_DNA_methylation1.39998458
35MP0003718_maternal_effect1.36924485
36MP0005075_abnormal_melanosome_morpholog1.36172236
37MP0002398_abnormal_bone_marrow1.35997628
38MP0003186_abnormal_redox_activity1.35357893
39MP0003315_abnormal_perineum_morphology1.34249668
40MP0001286_abnormal_eye_development1.33959079
41MP0000703_abnormal_thymus_morphology1.33611244
42MP0010030_abnormal_orbit_morphology1.32926323
43MP0005499_abnormal_olfactory_system1.32371096
44MP0005394_taste/olfaction_phenotype1.32371096
45MP0000631_abnormal_neuroendocrine_gland1.32179845
46MP0002697_abnormal_eye_size1.29457732
47MP0002722_abnormal_immune_system1.26888064
48MP0002736_abnormal_nociception_after1.22298502
49MP0000858_altered_metastatic_potential1.21657157
50MP0001697_abnormal_embryo_size1.20561351
51MP0001853_heart_inflammation1.20394538
52MP0000689_abnormal_spleen_morphology1.20269010
53MP0002234_abnormal_pharynx_morphology1.19725134
54MP0001485_abnormal_pinna_reflex1.19519916
55MP0003121_genomic_imprinting1.19360389
56MP0005084_abnormal_gallbladder_morpholo1.17188693
57MP0002080_prenatal_lethality1.16439392
58MP0002102_abnormal_ear_morphology1.15335372
59MP0005671_abnormal_response_to1.14076813
60MP0002210_abnormal_sex_determination1.13882043
61MP0003938_abnormal_ear_development1.13786997
62MP0002233_abnormal_nose_morphology1.12673782
63MP0003119_abnormal_digestive_system1.09221233
64MP0002095_abnormal_skin_pigmentation1.09096545
65MP0002429_abnormal_blood_cell1.08890490
66MP0001835_abnormal_antigen_presentation1.08598848
67MP0002837_dystrophic_cardiac_calcinosis1.05403404
68MP0002160_abnormal_reproductive_system1.05060375
69MP0003567_abnormal_fetal_cardiomyocyte1.04630738
70MP0003011_delayed_dark_adaptation1.02912777
71MP0005408_hypopigmentation1.02536065
72MP0005380_embryogenesis_phenotype1.01364779
73MP0001672_abnormal_embryogenesis/_devel1.01364779
74MP0002085_abnormal_embryonic_tissue1.00422770
75MP0004147_increased_porphyrin_level1.00327645
76MP0000716_abnormal_immune_system1.00273214
77MP0002938_white_spotting1.00112029
78MP0009785_altered_susceptibility_to0.98564463
79MP0004142_abnormal_muscle_tone0.96922578
80MP0002111_abnormal_tail_morphology0.95950763
81MP0006036_abnormal_mitochondrial_physio0.95261848
82MP0003941_abnormal_skin_development0.94583688
83MP0010352_gastrointestinal_tract_polyps0.94389857
84MP0001145_abnormal_male_reproductive0.94368747
85MP0000049_abnormal_middle_ear0.94317899
86MP0002653_abnormal_ependyma_morphology0.94134836
87MP0001293_anophthalmia0.93854824
88MP0000685_abnormal_immune_system0.93214529
89MP0001346_abnormal_lacrimal_gland0.92393186
90MP0002420_abnormal_adaptive_immunity0.91143239
91MP0001819_abnormal_immune_cell0.89306081
92MP0000566_synostosis0.88859131
93MP0002163_abnormal_gland_morphology0.88576815
94MP0003880_abnormal_central_pattern0.87906770
95MP0004381_abnormal_hair_follicle0.87584095
96MP0000465_gastrointestinal_hemorrhage0.86124839
97MP0001800_abnormal_humoral_immune0.85917541
98MP0003984_embryonic_growth_retardation0.85903434
99MP0005389_reproductive_system_phenotype0.85242939
100MP0003724_increased_susceptibility_to0.84479070
101MP0005025_abnormal_response_to0.84397949
102MP0008789_abnormal_olfactory_epithelium0.84121810
103MP0002405_respiratory_system_inflammati0.82980636
104MP0003806_abnormal_nucleotide_metabolis0.82950778
105MP0002148_abnormal_hypersensitivity_rea0.82869129
106MP0002088_abnormal_embryonic_growth/wei0.82835959
107MP0002452_abnormal_antigen_presenting0.82808020
108MP0000358_abnormal_cell_content/0.82807575
109MP0005391_vision/eye_phenotype0.81650994
110MP0000653_abnormal_sex_gland0.81431173
111MP0003878_abnormal_ear_physiology0.81028986
112MP0005377_hearing/vestibular/ear_phenot0.81028986
113MP0000372_irregular_coat_pigmentation0.80779477
114MP0002723_abnormal_immune_serum0.80438683
115MP0009672_abnormal_birth_weight0.80248065
116MP0008995_early_reproductive_senescence0.80148190
117MP0003755_abnormal_palate_morphology0.79283933
118MP0001929_abnormal_gametogenesis0.79149153
119MP0005253_abnormal_eye_physiology0.78451395
120MP0001984_abnormal_olfaction0.78088648
121MP0005000_abnormal_immune_tolerance0.77760831
122MP0003122_maternal_imprinting0.77087953
123MP0003656_abnormal_erythrocyte_physiolo0.76998942
124MP0001119_abnormal_female_reproductive0.75749754
125MP0009250_abnormal_appendicular_skeleto0.75697018
126MP0006035_abnormal_mitochondrial_morpho0.75693837
127MP0002751_abnormal_autonomic_nervous0.75578524
128MP0001188_hyperpigmentation0.75051340
129MP0005551_abnormal_eye_electrophysiolog0.74762605
130MP0003861_abnormal_nervous_system0.74679784
131MP0004133_heterotaxia0.74349322
132MP0002084_abnormal_developmental_patter0.74305393
133MP0002277_abnormal_respiratory_mucosa0.73803552
134MP0002090_abnormal_vision0.73267082
135MP0002086_abnormal_extraembryonic_tissu0.73209893
136MP0001919_abnormal_reproductive_system0.72731184
137MP0003698_abnormal_male_reproductive0.72662132
138MP0010307_abnormal_tumor_latency0.71458069
139MP0002006_tumorigenesis0.69793502
140MP0005195_abnormal_posterior_eye0.69621446
141MP0002638_abnormal_pupillary_reflex0.69404933
142MP0001764_abnormal_homeostasis0.68792638
143MP0000579_abnormal_nail_morphology0.68469624
144MP0001968_abnormal_touch/_nociception0.66664988
145MP0008872_abnormal_physiological_respon0.66653485
146MP0000537_abnormal_urethra_morphology0.66383544

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)7.32893750
2Abnormal number of erythroid precursors (HP:0012131)7.11434886
3Reticulocytopenia (HP:0001896)6.44118236
4Macrocytic anemia (HP:0001972)4.67193481
5Pallor (HP:0000980)4.64666689
6Aplastic anemia (HP:0001915)4.27761735
7Birth length less than 3rd percentile (HP:0003561)4.03546936
8Cerebral edema (HP:0002181)3.77156799
9Oral leukoplakia (HP:0002745)3.70566855
10Aplasia/Hypoplasia of the sacrum (HP:0008517)3.39252961
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.24540144
12Decreased activity of mitochondrial respiratory chain (HP:0008972)3.24540144
13Breast hypoplasia (HP:0003187)3.19665125
14Septo-optic dysplasia (HP:0100842)3.05874271
15Absent thumb (HP:0009777)2.95865212
1611 pairs of ribs (HP:0000878)2.94265737
17Chromsome breakage (HP:0040012)2.93190997
18Abnormality of the heme biosynthetic pathway (HP:0010472)2.90245470
19Mitochondrial inheritance (HP:0001427)2.89190672
20Increased hepatocellular lipid droplets (HP:0006565)2.87866499
21Leukodystrophy (HP:0002415)2.86426604
22Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.83290521
23Type I transferrin isoform profile (HP:0003642)2.80509337
24Hepatocellular necrosis (HP:0001404)2.78991494
25Abnormality of the preputium (HP:0100587)2.78817887
26Respiratory failure (HP:0002878)2.77380516
27Chromosomal breakage induced by crosslinking agents (HP:0003221)2.77033785
28Congenital, generalized hypertrichosis (HP:0004540)2.76292900
29Meckel diverticulum (HP:0002245)2.75777345
30Thrombocytosis (HP:0001894)2.73347144
31Acute necrotizing encephalopathy (HP:0006965)2.72598903
32Rough bone trabeculation (HP:0100670)2.72560758
33Patellar aplasia (HP:0006443)2.72334474
34Lactic acidosis (HP:0003128)2.70498280
35Colon cancer (HP:0003003)2.69170842
36Exertional dyspnea (HP:0002875)2.65450769
37Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.64126352
38Abnormality of the ileum (HP:0001549)2.64046116
39Abnormality of the labia minora (HP:0012880)2.62060493
40Aplasia/Hypoplasia of the patella (HP:0006498)2.60207959
41Increased CSF lactate (HP:0002490)2.59136524
42Microretrognathia (HP:0000308)2.58102983
43Triphalangeal thumb (HP:0001199)2.56858202
44Optic disc pallor (HP:0000543)2.55309288
45Premature graying of hair (HP:0002216)2.55072723
46Carpal bone hypoplasia (HP:0001498)2.49533839
47Increased serum lactate (HP:0002151)2.49495324
48Abnormal mitochondria in muscle tissue (HP:0008316)2.48385812
493-Methylglutaconic aciduria (HP:0003535)2.47813444
50Trismus (HP:0000211)2.46091292
51Lipid accumulation in hepatocytes (HP:0006561)2.44126617
52Abnormality of chromosome stability (HP:0003220)2.43738992
53Increased muscle lipid content (HP:0009058)2.40860025
54Selective tooth agenesis (HP:0001592)2.38228938
55Pancytopenia (HP:0001876)2.37404127
56Myelodysplasia (HP:0002863)2.35930924
57Hepatic necrosis (HP:0002605)2.31525248
58Abnormality of the anterior horn cell (HP:0006802)2.31217425
59Degeneration of anterior horn cells (HP:0002398)2.31217425
60Cleft eyelid (HP:0000625)2.30791568
61Abnormality of reticulocytes (HP:0004312)2.30360715
62Aplasia/Hypoplasia of the uvula (HP:0010293)2.30348016
63Cerebral hypomyelination (HP:0006808)2.30231349
64Abnormality of renal resorption (HP:0011038)2.30118663
65Microvesicular hepatic steatosis (HP:0001414)2.29593129
66Methylmalonic acidemia (HP:0002912)2.29299120
67Hyperglycinemia (HP:0002154)2.27444419
68Depressed nasal ridge (HP:0000457)2.17966683
69Absent septum pellucidum (HP:0001331)2.17960342
70Bone marrow hypocellularity (HP:0005528)2.17914758
71Respiratory difficulties (HP:0002880)2.17824386
72Horseshoe kidney (HP:0000085)2.17783198
73Hypoplasia of the radius (HP:0002984)2.14924056
74Lethargy (HP:0001254)2.14271431
75Sparse eyelashes (HP:0000653)2.12980434
76Cellular immunodeficiency (HP:0005374)2.12611989
77Pancreatic cysts (HP:0001737)2.12011372
78Pancreatic fibrosis (HP:0100732)2.10246637
79Muscle fiber atrophy (HP:0100295)2.09485580
80Reduced antithrombin III activity (HP:0001976)2.07872271
81Megaloblastic anemia (HP:0001889)2.06684748
82IgM deficiency (HP:0002850)2.05983281
83Secondary amenorrhea (HP:0000869)2.05281310
84Duodenal stenosis (HP:0100867)2.04194980
85Small intestinal stenosis (HP:0012848)2.04194980
86Increased intramyocellular lipid droplets (HP:0012240)2.04054998
87Absent radius (HP:0003974)2.03458092
88Poor head control (HP:0002421)2.02248150
89Progressive macrocephaly (HP:0004481)2.02000636
90Renal Fanconi syndrome (HP:0001994)2.01078299
91Exercise intolerance (HP:0003546)2.00453670
92Abnormality of midbrain morphology (HP:0002418)1.99963587
93Molar tooth sign on MRI (HP:0002419)1.99963587
94Multiple enchondromatosis (HP:0005701)1.99912051
95Pulmonary fibrosis (HP:0002206)1.99489429
96Pendular nystagmus (HP:0012043)1.99467363
97Abnormal lung lobation (HP:0002101)1.98890023
98Abnormality of methionine metabolism (HP:0010901)1.98860227
99Abnormal number of incisors (HP:0011064)1.98663177
100Abnormal protein glycosylation (HP:0012346)1.97169440
101Abnormal glycosylation (HP:0012345)1.97169440
102Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.97169440
103Abnormal protein N-linked glycosylation (HP:0012347)1.97169440
104Asplenia (HP:0001746)1.96297553
105Methylmalonic aciduria (HP:0012120)1.95908648
106Tracheoesophageal fistula (HP:0002575)1.94562324
107Acute encephalopathy (HP:0006846)1.94370844
108Hyperphosphaturia (HP:0003109)1.94162930
109Abnormality of serum amino acid levels (HP:0003112)1.93079922
110Neoplasm of the pancreas (HP:0002894)1.92151276
111Abnormal trabecular bone morphology (HP:0100671)1.91891385
112Abnormality of the septum pellucidum (HP:0007375)1.91850583
113Stenosis of the external auditory canal (HP:0000402)1.90338447
114Medulloblastoma (HP:0002885)1.89845062
115Abnormality of urine glucose concentration (HP:0011016)1.88775213
116Glycosuria (HP:0003076)1.88775213
117Lymphoma (HP:0002665)1.88487664
118Aplasia involving forearm bones (HP:0009822)1.88288508
119Absent forearm bone (HP:0003953)1.88288508
120Maternal diabetes (HP:0009800)1.86842747
121Progressive muscle weakness (HP:0003323)1.86517922
122Bilateral microphthalmos (HP:0007633)1.85981600
123Petechiae (HP:0000967)1.85289518
124Absent rod-and cone-mediated responses on ERG (HP:0007688)1.85261105
125Atresia of the external auditory canal (HP:0000413)1.84006855
126X-linked dominant inheritance (HP:0001423)1.83055641
127Partial duplication of thumb phalanx (HP:0009944)1.82909362
128Abnormal hemoglobin (HP:0011902)1.82663851
129True hermaphroditism (HP:0010459)1.82341208
130CNS demyelination (HP:0007305)1.81850854
131Supernumerary spleens (HP:0009799)1.81447955
132Severe visual impairment (HP:0001141)1.81024512
133Type 2 muscle fiber atrophy (HP:0003554)1.80372985
134Optic nerve coloboma (HP:0000588)1.79492405
135Rib fusion (HP:0000902)1.78500477
136Sclerocornea (HP:0000647)1.77760282
137Esophageal atresia (HP:0002032)1.75784652
138Abnormality of aspartate family amino acid metabolism (HP:0010899)1.73409276
139Partial duplication of the phalanx of hand (HP:0009999)1.72267786
140Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.72076694
141Hypoplasia of the pons (HP:0012110)1.71929467
142Anophthalmia (HP:0000528)1.69289066
143Abnormality of alanine metabolism (HP:0010916)1.68827839
144Hyperalaninemia (HP:0003348)1.68827839
145Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.68827839
146Optic nerve hypoplasia (HP:0000609)1.66566947

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.77435564
2BUB14.45778452
3WEE13.85086470
4NME23.84823790
5STK163.25488296
6EIF2AK13.00917469
7TLK13.00090803
8CDC72.99184979
9SRPK12.96526817
10VRK12.66286556
11TESK22.45114684
12PLK42.29554481
13EIF2AK31.98461493
14ACVR1B1.97157872
15DYRK31.96729959
16TAF11.93603393
17PIM21.91857614
18BRSK21.91776162
19MKNK11.89449808
20NUAK11.80012069
21NEK21.73597229
22MKNK21.70722272
23WNK31.69352010
24PLK11.56571218
25CDK71.56245795
26TSSK61.55922954
27RPS6KA41.54671959
28TTK1.50496848
29KDR1.48349412
30AURKB1.46999046
31RPS6KB21.43582859
32CDK81.34734632
33ATR1.34270804
34BMPR1B1.29216630
35IRAK41.23925048
36CDK191.21972742
37PBK1.21866659
38AURKA1.20311604
39NME11.13405799
40SCYL21.12082666
41IRAK31.10023760
42MAP3K101.09352027
43PNCK1.09204886
44PASK1.07825435
45BRSK11.03434268
46TESK11.02986285
47CHEK21.02160916
48LRRK21.01368429
49MAP4K10.99743922
50MAP3K110.96455915
51PDK20.95309848
52BLK0.94129460
53CDK40.92438692
54MAP3K80.92156201
55TEC0.91835499
56PAK40.90640964
57BCKDK0.89231606
58EIF2AK20.87745140
59PIM10.85628616
60TRIM280.83449650
61MAP4K20.82080743
62PLK30.80645363
63MST40.79331327
64RPS6KA50.78375058
65CCNB10.77365808
66BTK0.76897768
67ZAK0.76836258
68TGFBR10.76574764
69STK40.76492930
70CSNK2A10.76366324
71STK100.75976844
72GRK10.75478619
73CSNK2A20.73909631
74DYRK20.73493038
75BRAF0.72829238
76CLK10.71987856
77MAPKAPK30.71175623
78ADRBK20.70450040
79CHEK10.69422910
80INSRR0.69183031
81CSNK1G10.67081159
82CSNK1E0.66382798
83ILK0.65805227
84STK30.64772690
85ALK0.63857867
86LIMK10.62302144
87PAK10.62252614
88OXSR10.60834978
89ABL20.59296755
90PRKCG0.59189973
91FLT30.57439315
92ATM0.57013277
93WNK40.55868338
94MAP2K70.55010675
95MAP3K40.54983482
96CSNK1G20.54975543
97CSNK1G30.54972929
98KIT0.54927189
99CDK30.54825194
100YES10.54376764
101STK240.53297438
102MAP3K120.52967023
103CDK20.52150700
104CASK0.51104225
105TXK0.50924765
106STK38L0.49342170
107NLK0.49247456
108NEK10.45301534
109TNIK0.45175344
110IKBKB0.43990731
111LYN0.42047157
112PRKCI0.40911633
113PLK20.40808695
114FGFR10.40788242
115ZAP700.40702586
116STK390.39797271
117IRAK10.39510224
118MUSK0.38691115
119EPHB20.35443660
120PRKDC0.35239598
121CDK10.34477705
122TYK20.33820323
123CSNK1A10.33451772
124TAOK20.33094300
125JAK30.32216577
126IRAK20.32040229
127EEF2K0.30342630
128EPHA20.28471739
129TIE10.28099326
130NEK90.27848462
131CSNK1A1L0.25680215
132MAP2K30.25499190
133DAPK30.25431899
134MAPKAPK50.25069253
135MAPKAPK20.24934634
136ERBB40.24414817
137AKT20.23211012
138LCK0.18983480
139CDK60.18896766

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.73190763
2DNA replication_Homo sapiens_hsa030304.78859198
3Mismatch repair_Homo sapiens_hsa034303.77874554
4RNA polymerase_Homo sapiens_hsa030203.55400869
5Proteasome_Homo sapiens_hsa030503.40416670
6* Spliceosome_Homo sapiens_hsa030403.30371627
7Homologous recombination_Homo sapiens_hsa034403.05541037
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.99890609
9Base excision repair_Homo sapiens_hsa034102.85235053
10Pyrimidine metabolism_Homo sapiens_hsa002402.77255892
11Nucleotide excision repair_Homo sapiens_hsa034202.73455464
12RNA transport_Homo sapiens_hsa030132.36739082
13Fanconi anemia pathway_Homo sapiens_hsa034602.09044664
14One carbon pool by folate_Homo sapiens_hsa006702.06466103
15Cell cycle_Homo sapiens_hsa041102.05731636
16Protein export_Homo sapiens_hsa030601.96006864
17RNA degradation_Homo sapiens_hsa030181.89463954
18Basal transcription factors_Homo sapiens_hsa030221.84006226
19Non-homologous end-joining_Homo sapiens_hsa034501.74942817
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.73529735
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.67402723
22Parkinsons disease_Homo sapiens_hsa050121.63980732
23Oxidative phosphorylation_Homo sapiens_hsa001901.61951637
24Huntingtons disease_Homo sapiens_hsa050161.45014773
25Purine metabolism_Homo sapiens_hsa002301.43344004
26p53 signaling pathway_Homo sapiens_hsa041151.31720057
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.25634587
28mRNA surveillance pathway_Homo sapiens_hsa030151.22226748
29Sulfur relay system_Homo sapiens_hsa041221.17205665
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.14299011
31Systemic lupus erythematosus_Homo sapiens_hsa053221.09822671
32Pyruvate metabolism_Homo sapiens_hsa006201.06188895
33Epstein-Barr virus infection_Homo sapiens_hsa051691.01799353
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.01510072
35Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.00248183
36Folate biosynthesis_Homo sapiens_hsa007900.97203992
37Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.96687111
38Herpes simplex infection_Homo sapiens_hsa051680.96256309
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.93750554
40Alzheimers disease_Homo sapiens_hsa050100.91600470
41Antigen processing and presentation_Homo sapiens_hsa046120.90852315
42Propanoate metabolism_Homo sapiens_hsa006400.89453458
43Primary immunodeficiency_Homo sapiens_hsa053400.80318536
44Fatty acid elongation_Homo sapiens_hsa000620.74073084
45Vitamin B6 metabolism_Homo sapiens_hsa007500.71072727
46Steroid biosynthesis_Homo sapiens_hsa001000.70979468
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.65993718
48Pentose phosphate pathway_Homo sapiens_hsa000300.65746905
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.64171274
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63221436
51N-Glycan biosynthesis_Homo sapiens_hsa005100.61192885
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60616188
53Vitamin digestion and absorption_Homo sapiens_hsa049770.58474292
54Cyanoamino acid metabolism_Homo sapiens_hsa004600.57654417
55Viral carcinogenesis_Homo sapiens_hsa052030.57546429
56HTLV-I infection_Homo sapiens_hsa051660.56866636
57Glutathione metabolism_Homo sapiens_hsa004800.56753775
58Thyroid cancer_Homo sapiens_hsa052160.55417273
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55329959
60Cysteine and methionine metabolism_Homo sapiens_hsa002700.55066228
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.54087039
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.51736037
63Legionellosis_Homo sapiens_hsa051340.51192763
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50885290
65Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50847252
66Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49457177
67Measles_Homo sapiens_hsa051620.48651463
68Oocyte meiosis_Homo sapiens_hsa041140.47780991
69Butanoate metabolism_Homo sapiens_hsa006500.46174542
70Phototransduction_Homo sapiens_hsa047440.45600883
71Hematopoietic cell lineage_Homo sapiens_hsa046400.45019908
72Maturity onset diabetes of the young_Homo sapiens_hsa049500.43841015
73Transcriptional misregulation in cancer_Homo sapiens_hsa052020.41950846
74Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.40858611
75Carbon metabolism_Homo sapiens_hsa012000.40758371
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40390603
77Peroxisome_Homo sapiens_hsa041460.40167572
78Apoptosis_Homo sapiens_hsa042100.38852077
79Alcoholism_Homo sapiens_hsa050340.37756260
80NF-kappa B signaling pathway_Homo sapiens_hsa040640.37599378
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.36866453
82RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.36856362
83Arachidonic acid metabolism_Homo sapiens_hsa005900.36370742
84Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36169448
85Hedgehog signaling pathway_Homo sapiens_hsa043400.35505501
86Chemical carcinogenesis_Homo sapiens_hsa052040.35042588
87Intestinal immune network for IgA production_Homo sapiens_hsa046720.35007692
88Allograft rejection_Homo sapiens_hsa053300.34835961
89Metabolic pathways_Homo sapiens_hsa011000.34356953
90Graft-versus-host disease_Homo sapiens_hsa053320.33969311
91Shigellosis_Homo sapiens_hsa051310.33892629
92Retinol metabolism_Homo sapiens_hsa008300.33285638
932-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.33094202
94Tryptophan metabolism_Homo sapiens_hsa003800.32447196
95Asthma_Homo sapiens_hsa053100.31674935
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.31185224
97Caffeine metabolism_Homo sapiens_hsa002320.30883749
98NOD-like receptor signaling pathway_Homo sapiens_hsa046210.30055765
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29833450
100Collecting duct acid secretion_Homo sapiens_hsa049660.29789430
101Small cell lung cancer_Homo sapiens_hsa052220.29778878
102Nitrogen metabolism_Homo sapiens_hsa009100.29422178
103Hepatitis B_Homo sapiens_hsa051610.28677273
104Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.28119319
105Selenocompound metabolism_Homo sapiens_hsa004500.27654565
106Sulfur metabolism_Homo sapiens_hsa009200.27186695
107beta-Alanine metabolism_Homo sapiens_hsa004100.27058997
108Nicotine addiction_Homo sapiens_hsa050330.26593170
109Arginine and proline metabolism_Homo sapiens_hsa003300.26107838
110Acute myeloid leukemia_Homo sapiens_hsa052210.24300501
111Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.24269619
112Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.23936789
113Cardiac muscle contraction_Homo sapiens_hsa042600.23816665
114Wnt signaling pathway_Homo sapiens_hsa043100.23677279
115Tyrosine metabolism_Homo sapiens_hsa003500.22992351
116Fatty acid degradation_Homo sapiens_hsa000710.21275060
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.21147752
118Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.20627320
119Notch signaling pathway_Homo sapiens_hsa043300.20605104
120Biosynthesis of amino acids_Homo sapiens_hsa012300.20458855
121MicroRNAs in cancer_Homo sapiens_hsa052060.19927751
122Basal cell carcinoma_Homo sapiens_hsa052170.19920496
123Leishmaniasis_Homo sapiens_hsa051400.19890183
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.19246246
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.18442843
126Other glycan degradation_Homo sapiens_hsa005110.18428977
127Influenza A_Homo sapiens_hsa051640.18410982
128Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.17606094
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.17204315
130Fat digestion and absorption_Homo sapiens_hsa049750.16883997
131Olfactory transduction_Homo sapiens_hsa047400.15517155
132Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.14744088
133TGF-beta signaling pathway_Homo sapiens_hsa043500.14363016
134Jak-STAT signaling pathway_Homo sapiens_hsa046300.14156999
135Linoleic acid metabolism_Homo sapiens_hsa005910.13634715
136Autoimmune thyroid disease_Homo sapiens_hsa053200.13158345
137Bladder cancer_Homo sapiens_hsa052190.12985811
138Hippo signaling pathway_Homo sapiens_hsa043900.12701462
139Galactose metabolism_Homo sapiens_hsa000520.12564163
140Steroid hormone biosynthesis_Homo sapiens_hsa001400.11297582
141Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.10940732
142Pathways in cancer_Homo sapiens_hsa052000.10576519
143Primary bile acid biosynthesis_Homo sapiens_hsa001200.10295245
144Colorectal cancer_Homo sapiens_hsa052100.09841314
145Renin-angiotensin system_Homo sapiens_hsa046140.09656202
146Regulation of autophagy_Homo sapiens_hsa041400.08867160
147Fatty acid metabolism_Homo sapiens_hsa012120.08539243
148Pertussis_Homo sapiens_hsa051330.07243819
149Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.05178088

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