

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 8.41805211 |
| 2 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 8.08821075 |
| 3 | signal complex assembly (GO:0007172) | 7.63709845 |
| 4 | maturation of 5.8S rRNA (GO:0000460) | 7.53510657 |
| 5 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) | 6.59052213 |
| 6 | positive regulation of translational initiation (GO:0045948) | 6.54323838 |
| 7 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 6.54109351 |
| 8 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 6.43475813 |
| 9 | secretory granule organization (GO:0033363) | 6.42502169 |
| 10 | regulation of mitochondrial translation (GO:0070129) | 6.11897783 |
| 11 | cytochrome complex assembly (GO:0017004) | 5.97686511 |
| 12 | megakaryocyte development (GO:0035855) | 5.94075707 |
| 13 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 5.20462872 |
| 14 | protein complex biogenesis (GO:0070271) | 4.79550962 |
| 15 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.63556734 |
| 16 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.63556734 |
| 17 | pseudouridine synthesis (GO:0001522) | 4.53103389 |
| 18 | negative regulation of translational initiation (GO:0045947) | 4.46998743 |
| 19 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 4.33055630 |
| 20 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.31140977 |
| 21 | DNA double-strand break processing (GO:0000729) | 4.25597427 |
| 22 | neural tube formation (GO:0001841) | 4.18921510 |
| 23 | platelet formation (GO:0030220) | 4.12038546 |
| 24 | limb bud formation (GO:0060174) | 4.11342370 |
| 25 | C4-dicarboxylate transport (GO:0015740) | 4.04276638 |
| 26 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.96036462 |
| 27 | regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) | 3.74674982 |
| 28 | peptidyl-histidine modification (GO:0018202) | 3.72476340 |
| 29 | regulation of translation in response to stress (GO:0043555) | 3.71981960 |
| 30 | respiratory chain complex IV assembly (GO:0008535) | 3.67082677 |
| 31 | neuronal action potential propagation (GO:0019227) | 3.57444780 |
| 32 | presynaptic membrane assembly (GO:0097105) | 3.56756579 |
| 33 | ribosomal small subunit biogenesis (GO:0042274) | 3.48566792 |
| 34 | negative regulation of mast cell activation (GO:0033004) | 3.46172969 |
| 35 | presynaptic membrane organization (GO:0097090) | 3.39646524 |
| 36 | negative regulation of membrane potential (GO:0045837) | 3.32146446 |
| 37 | replication fork processing (GO:0031297) | 3.28677474 |
| 38 | rRNA modification (GO:0000154) | 3.26216296 |
| 39 | platelet dense granule organization (GO:0060155) | 3.21324001 |
| 40 | piRNA metabolic process (GO:0034587) | 3.20488518 |
| 41 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902230) | 3.16247400 |
| 42 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.15336775 |
| 43 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.14128325 |
| 44 | ubiquinone biosynthetic process (GO:0006744) | 3.11802997 |
| 45 | chromatin remodeling at centromere (GO:0031055) | 3.08768745 |
| 46 | behavioral response to nicotine (GO:0035095) | 3.07807001 |
| 47 | ubiquinone metabolic process (GO:0006743) | 3.05948248 |
| 48 | olfactory bulb development (GO:0021772) | 3.02013471 |
| 49 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.01678311 |
| 50 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.93894111 |
| 51 | mechanosensory behavior (GO:0007638) | 2.92671744 |
| 52 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.88859328 |
| 53 | DNA replication-independent nucleosome organization (GO:0034724) | 2.88859328 |
| 54 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.87644487 |
| 55 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.87285807 |
| 56 | NADH dehydrogenase complex assembly (GO:0010257) | 2.87285807 |
| 57 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.87285807 |
| 58 | resolution of meiotic recombination intermediates (GO:0000712) | 2.87200012 |
| 59 | kinetochore organization (GO:0051383) | 2.86929686 |
| 60 | histone exchange (GO:0043486) | 2.83390604 |
| 61 | CENP-A containing nucleosome assembly (GO:0034080) | 2.82260412 |
| 62 | intraciliary transport (GO:0042073) | 2.79565222 |
| 63 | positive regulation of macrophage differentiation (GO:0045651) | 2.79548937 |
| 64 | kinetochore assembly (GO:0051382) | 2.79159792 |
| 65 | regulation of signal transduction by p53 class mediator (GO:1901796) | 2.78689410 |
| 66 | regulation of activation of Janus kinase activity (GO:0010533) | 2.75918806 |
| 67 | protein-cofactor linkage (GO:0018065) | 2.73500825 |
| 68 | signal peptide processing (GO:0006465) | 2.71704699 |
| 69 | histone H2A acetylation (GO:0043968) | 2.71643199 |
| 70 | DNA packaging (GO:0006323) | 2.70241874 |
| 71 | microtubule depolymerization (GO:0007019) | 2.67392984 |
| 72 | T cell apoptotic process (GO:0070231) | 2.65890676 |
| 73 | regulation of timing of cell differentiation (GO:0048505) | 2.65840173 |
| 74 | retinal ganglion cell axon guidance (GO:0031290) | 2.63908550 |
| 75 | myeloid cell development (GO:0061515) | 2.63756893 |
| 76 | cell proliferation in forebrain (GO:0021846) | 2.61753455 |
| 77 | double-strand break repair via homologous recombination (GO:0000724) | 2.61731177 |
| 78 | recombinational repair (GO:0000725) | 2.61495494 |
| 79 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.59947415 |
| 80 | DNA damage response, detection of DNA damage (GO:0042769) | 2.59142614 |
| 81 | somite development (GO:0061053) | 2.58145377 |
| 82 | postsynaptic membrane organization (GO:0001941) | 2.54289166 |
| 83 | oligodendrocyte development (GO:0014003) | 2.53089709 |
| 84 | sympathetic nervous system development (GO:0048485) | 2.51610233 |
| 85 | cornea development in camera-type eye (GO:0061303) | 2.51315777 |
| 86 | otic vesicle formation (GO:0030916) | 2.50416631 |
| 87 | quinone biosynthetic process (GO:1901663) | 2.50366508 |
| 88 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.49823943 |
| 89 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.44807958 |
| 90 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.43910872 |
| 91 | protein kinase B signaling (GO:0043491) | 2.40544732 |
| 92 | epithelial cilium movement (GO:0003351) | 2.39466265 |
| 93 | gamma-aminobutyric acid transport (GO:0015812) | 2.39223650 |
| 94 | positive regulation of response to DNA damage stimulus (GO:2001022) | 2.39162887 |
| 95 | transmission of nerve impulse (GO:0019226) | 2.39133748 |
| 96 | plasma membrane fusion (GO:0045026) | 2.38580966 |
| 97 | protein K6-linked ubiquitination (GO:0085020) | 2.38069116 |
| 98 | translesion synthesis (GO:0019985) | 2.35480852 |
| 99 | regulation of development, heterochronic (GO:0040034) | 2.34378066 |
| 100 | RNA localization (GO:0006403) | 11.0796412 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 4.95490718 |
| 2 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.73555450 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.75307825 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.73659368 |
| 5 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.61343641 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.59286585 |
| 7 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.58334954 |
| 8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.58113261 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.55462049 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.46161931 |
| 11 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.24075020 |
| 12 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.15806331 |
| 13 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.13448635 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.12807248 |
| 15 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.04288663 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.01922032 |
| 17 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.99278238 |
| 18 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.97443080 |
| 19 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.94362002 |
| 20 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.87238261 |
| 21 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.86444679 |
| 22 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.85846637 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.85487200 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84384413 |
| 25 | FUS_26573619_Chip-Seq_HEK293_Human | 1.83835004 |
| 26 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.81281935 |
| 27 | P300_19829295_ChIP-Seq_ESCs_Human | 1.77206063 |
| 28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.74935087 |
| 29 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.70317557 |
| 30 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.69762942 |
| 31 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.67868333 |
| 32 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.65000467 |
| 33 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.63488463 |
| 34 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.61776448 |
| 35 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.57218367 |
| 36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.57100631 |
| 37 | TP53_16413492_ChIP-PET_HCT116_Human | 1.52910346 |
| 38 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.51790704 |
| 39 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.51271085 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.51227241 |
| 41 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.50783703 |
| 42 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.49353883 |
| 43 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.49136968 |
| 44 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.48746880 |
| 45 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.48736941 |
| 46 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48736941 |
| 47 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.48622789 |
| 48 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.47456383 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.47245536 |
| 50 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.46380072 |
| 51 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.43614275 |
| 52 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.39695909 |
| 53 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.38400450 |
| 54 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.34570121 |
| 55 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.32316340 |
| 56 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.31787572 |
| 57 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.31510826 |
| 58 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.30845367 |
| 59 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.30619301 |
| 60 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.30492231 |
| 61 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.30365433 |
| 62 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.29711125 |
| 63 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.27619165 |
| 64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27114903 |
| 65 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.26858977 |
| 66 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.23853093 |
| 67 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.23045241 |
| 68 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22492459 |
| 69 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21217990 |
| 70 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.20673597 |
| 71 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.20134977 |
| 72 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.19893558 |
| 73 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.19403777 |
| 74 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.18342594 |
| 75 | STAT3_23295773_ChIP-Seq_U87_Human | 1.18065179 |
| 76 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.17718869 |
| 77 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17234965 |
| 78 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.16220210 |
| 79 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.14448956 |
| 80 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12398095 |
| 81 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.11504969 |
| 82 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.09688858 |
| 83 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.09088918 |
| 84 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.07430780 |
| 85 | TCF4_23295773_ChIP-Seq_U87_Human | 1.07022046 |
| 86 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06949834 |
| 87 | AR_25329375_ChIP-Seq_VCAP_Human | 1.06406237 |
| 88 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.05979558 |
| 89 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05737018 |
| 90 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.05684378 |
| 91 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.03975299 |
| 92 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.03670470 |
| 93 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03439091 |
| 94 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.02524090 |
| 95 | KDM2B_26808549_Chip-Seq_REH_Human | 1.01713464 |
| 96 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.01682730 |
| 97 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.01014610 |
| 98 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.00208756 |
| 99 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.98645336 |
| 100 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.98300822 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 4.77066451 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.81482683 |
| 3 | MP0004145_abnormal_muscle_electrophysio | 2.73929457 |
| 4 | MP0003880_abnormal_central_pattern | 2.31081488 |
| 5 | MP0002163_abnormal_gland_morphology | 2.21464460 |
| 6 | MP0008789_abnormal_olfactory_epithelium | 2.17413842 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.14951035 |
| 8 | MP0002736_abnormal_nociception_after | 2.13841050 |
| 9 | MP0004885_abnormal_endolymph | 2.12801802 |
| 10 | MP0003787_abnormal_imprinting | 2.12307953 |
| 11 | MP0002938_white_spotting | 2.02291614 |
| 12 | MP0010094_abnormal_chromosome_stability | 1.95123143 |
| 13 | MP0002102_abnormal_ear_morphology | 1.80776344 |
| 14 | MP0000049_abnormal_middle_ear | 1.76217519 |
| 15 | MP0005187_abnormal_penis_morphology | 1.73881729 |
| 16 | MP0000778_abnormal_nervous_system | 1.68485097 |
| 17 | MP0008058_abnormal_DNA_repair | 1.64524770 |
| 18 | MP0005499_abnormal_olfactory_system | 1.64432896 |
| 19 | MP0005394_taste/olfaction_phenotype | 1.64432896 |
| 20 | MP0006035_abnormal_mitochondrial_morpho | 1.58748731 |
| 21 | MP0005248_abnormal_Harderian_gland | 1.57874476 |
| 22 | MP0005646_abnormal_pituitary_gland | 1.57508858 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.57040785 |
| 24 | MP0005253_abnormal_eye_physiology | 1.55830190 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.55550156 |
| 26 | MP0003121_genomic_imprinting | 1.52177678 |
| 27 | MP0008877_abnormal_DNA_methylation | 1.51938419 |
| 28 | MP0002751_abnormal_autonomic_nervous | 1.51420569 |
| 29 | MP0002277_abnormal_respiratory_mucosa | 1.50035623 |
| 30 | MP0003937_abnormal_limbs/digits/tail_de | 1.49884871 |
| 31 | MP0009250_abnormal_appendicular_skeleto | 1.49185524 |
| 32 | MP0000534_abnormal_ureter_morphology | 1.48896548 |
| 33 | MP0001529_abnormal_vocalization | 1.48264694 |
| 34 | MP0001486_abnormal_startle_reflex | 1.43831717 |
| 35 | MP0003755_abnormal_palate_morphology | 1.40340576 |
| 36 | MP0005174_abnormal_tail_pigmentation | 1.39962199 |
| 37 | MP0009046_muscle_twitch | 1.37278175 |
| 38 | MP0009745_abnormal_behavioral_response | 1.34912103 |
| 39 | MP0010307_abnormal_tumor_latency | 1.34276311 |
| 40 | MP0002233_abnormal_nose_morphology | 1.33938496 |
| 41 | MP0005423_abnormal_somatic_nervous | 1.30753660 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.29054704 |
| 43 | MP0004147_increased_porphyrin_level | 1.26305760 |
| 44 | MP0002638_abnormal_pupillary_reflex | 1.25666831 |
| 45 | MP0005410_abnormal_fertilization | 1.23539272 |
| 46 | MP0006276_abnormal_autonomic_nervous | 1.23310922 |
| 47 | MP0003137_abnormal_impulse_conducting | 1.22148761 |
| 48 | MP0004957_abnormal_blastocyst_morpholog | 1.20730722 |
| 49 | MP0003011_delayed_dark_adaptation | 1.20406977 |
| 50 | MP0003315_abnormal_perineum_morphology | 1.19106936 |
| 51 | MP0000631_abnormal_neuroendocrine_gland | 1.19027642 |
| 52 | MP0002184_abnormal_innervation | 1.19002184 |
| 53 | MP0003195_calcinosis | 1.16445122 |
| 54 | MP0002095_abnormal_skin_pigmentation | 1.15258987 |
| 55 | MP0005367_renal/urinary_system_phenotyp | 1.14810371 |
| 56 | MP0000516_abnormal_urinary_system | 1.14810371 |
| 57 | MP0009697_abnormal_copulation | 1.13422388 |
| 58 | MP0002272_abnormal_nervous_system | 1.13028808 |
| 59 | MP0004142_abnormal_muscle_tone | 1.10519251 |
| 60 | MP0003119_abnormal_digestive_system | 1.10253153 |
| 61 | MP0005379_endocrine/exocrine_gland_phen | 1.10183981 |
| 62 | MP0000647_abnormal_sebaceous_gland | 1.09028567 |
| 63 | MP0002249_abnormal_larynx_morphology | 1.08648238 |
| 64 | MP0005503_abnormal_tendon_morphology | 1.08328891 |
| 65 | MP0003122_maternal_imprinting | 1.06878669 |
| 66 | MP0000462_abnormal_digestive_system | 1.05539566 |
| 67 | MP0008932_abnormal_embryonic_tissue | 1.04701959 |
| 68 | MP0002557_abnormal_social/conspecific_i | 1.04107848 |
| 69 | MP0002752_abnormal_somatic_nervous | 1.03987162 |
| 70 | MP0003635_abnormal_synaptic_transmissio | 1.01279795 |
| 71 | MP0002735_abnormal_chemical_nociception | 1.01011893 |
| 72 | MP0002822_catalepsy | 0.99744972 |
| 73 | MP0004215_abnormal_myocardial_fiber | 0.99110105 |
| 74 | MP0003718_maternal_effect | 0.97965528 |
| 75 | MP0002210_abnormal_sex_determination | 0.96360882 |
| 76 | MP0001485_abnormal_pinna_reflex | 0.96298971 |
| 77 | MP0001286_abnormal_eye_development | 0.95399842 |
| 78 | MP0002160_abnormal_reproductive_system | 0.94376534 |
| 79 | MP0003385_abnormal_body_wall | 0.94128023 |
| 80 | MP0000026_abnormal_inner_ear | 0.94056156 |
| 81 | MP0005084_abnormal_gallbladder_morpholo | 0.93936961 |
| 82 | MP0005391_vision/eye_phenotype | 0.93611477 |
| 83 | MP0003938_abnormal_ear_development | 0.92546957 |
| 84 | MP0005389_reproductive_system_phenotype | 0.92046185 |
| 85 | MP0005623_abnormal_meninges_morphology | 0.90572568 |
| 86 | MP0003567_abnormal_fetal_cardiomyocyte | 0.89349131 |
| 87 | MP0005195_abnormal_posterior_eye | 0.88497689 |
| 88 | MP0003111_abnormal_nucleus_morphology | 0.87811975 |
| 89 | MP0002234_abnormal_pharynx_morphology | 0.87262062 |
| 90 | MP0004133_heterotaxia | 0.86767647 |
| 91 | MP0003786_premature_aging | 0.86579413 |
| 92 | MP0003693_abnormal_embryo_hatching | 0.85665299 |
| 93 | MP0002734_abnormal_mechanical_nocicepti | 0.85625313 |
| 94 | MP0003861_abnormal_nervous_system | 0.83945892 |
| 95 | MP0003186_abnormal_redox_activity | 0.83787706 |
| 96 | MP0000579_abnormal_nail_morphology | 0.83504961 |
| 97 | MP0002064_seizures | 0.82359976 |
| 98 | MP0004043_abnormal_pH_regulation | 0.81952905 |
| 99 | MP0000428_abnormal_craniofacial_morphol | 0.81453024 |
| 100 | MP0001119_abnormal_female_reproductive | 0.80997682 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hyperventilation (HP:0002883) | 3.95985448 |
| 2 | Cerebral hypomyelination (HP:0006808) | 3.90822860 |
| 3 | Focal motor seizures (HP:0011153) | 3.38695901 |
| 4 | True hermaphroditism (HP:0010459) | 3.11022994 |
| 5 | 3-Methylglutaconic aciduria (HP:0003535) | 2.99786935 |
| 6 | Abnormality of midbrain morphology (HP:0002418) | 2.89888054 |
| 7 | Molar tooth sign on MRI (HP:0002419) | 2.89888054 |
| 8 | Chronic hepatic failure (HP:0100626) | 2.88608822 |
| 9 | Secondary amenorrhea (HP:0000869) | 2.87501218 |
| 10 | Delusions (HP:0000746) | 2.87486030 |
| 11 | Premature ovarian failure (HP:0008209) | 2.82765797 |
| 12 | Pancreatic cysts (HP:0001737) | 2.73709221 |
| 13 | Nephronophthisis (HP:0000090) | 2.73390642 |
| 14 | Concave nail (HP:0001598) | 2.70090177 |
| 15 | Acute necrotizing encephalopathy (HP:0006965) | 2.69474612 |
| 16 | Pancreatic fibrosis (HP:0100732) | 2.67843169 |
| 17 | Abnormality of chromosome stability (HP:0003220) | 2.66426375 |
| 18 | Intestinal atresia (HP:0011100) | 2.62451299 |
| 19 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.61815612 |
| 20 | Colon cancer (HP:0003003) | 2.57768120 |
| 21 | Volvulus (HP:0002580) | 2.56970646 |
| 22 | Astrocytoma (HP:0009592) | 2.55771880 |
| 23 | Abnormality of the astrocytes (HP:0100707) | 2.55771880 |
| 24 | Pendular nystagmus (HP:0012043) | 2.53800163 |
| 25 | Abnormality of the labia minora (HP:0012880) | 2.49297080 |
| 26 | Testicular atrophy (HP:0000029) | 2.49090509 |
| 27 | Dyschromatopsia (HP:0007641) | 2.47559820 |
| 28 | Small epiphyses (HP:0010585) | 2.46628525 |
| 29 | Hemiparesis (HP:0001269) | 2.41004573 |
| 30 | Hepatoblastoma (HP:0002884) | 2.40346458 |
| 31 | Meckel diverticulum (HP:0002245) | 2.39924354 |
| 32 | Abnormality of the renal medulla (HP:0100957) | 2.34071716 |
| 33 | Abnormality of the ileum (HP:0001549) | 2.33686908 |
| 34 | Abnormality of the renal cortex (HP:0011035) | 2.32291495 |
| 35 | Hemiplegia (HP:0002301) | 2.31709896 |
| 36 | Bifid tongue (HP:0010297) | 2.27953734 |
| 37 | Dyskinesia (HP:0100660) | 2.25999122 |
| 38 | Abolished electroretinogram (ERG) (HP:0000550) | 2.25304140 |
| 39 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.24724537 |
| 40 | Abnormal biliary tract physiology (HP:0012439) | 2.24000054 |
| 41 | Bile duct proliferation (HP:0001408) | 2.24000054 |
| 42 | Progressive macrocephaly (HP:0004481) | 2.23822818 |
| 43 | Triphalangeal thumb (HP:0001199) | 2.23793318 |
| 44 | Median cleft lip (HP:0000161) | 2.23517264 |
| 45 | Increased corneal curvature (HP:0100692) | 2.20797241 |
| 46 | Keratoconus (HP:0000563) | 2.20797241 |
| 47 | Glioma (HP:0009733) | 2.16316839 |
| 48 | Increased CSF lactate (HP:0002490) | 2.15130765 |
| 49 | Mitochondrial inheritance (HP:0001427) | 2.14865552 |
| 50 | Focal seizures (HP:0007359) | 2.14582720 |
| 51 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.14166135 |
| 52 | Acute encephalopathy (HP:0006846) | 2.13945929 |
| 53 | Congenital stationary night blindness (HP:0007642) | 2.13445522 |
| 54 | Patellar aplasia (HP:0006443) | 2.10897308 |
| 55 | Medial flaring of the eyebrow (HP:0010747) | 2.07470368 |
| 56 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.05631158 |
| 57 | Morphological abnormality of the inner ear (HP:0011390) | 2.05609959 |
| 58 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.03923435 |
| 59 | Ectopic kidney (HP:0000086) | 2.02807918 |
| 60 | Abnormal lung lobation (HP:0002101) | 2.02661344 |
| 61 | Hyperglycinemia (HP:0002154) | 2.01996824 |
| 62 | Short tibia (HP:0005736) | 2.01265712 |
| 63 | CNS hypomyelination (HP:0003429) | 1.98336928 |
| 64 | Irregular epiphyses (HP:0010582) | 1.97694923 |
| 65 | Oligodactyly (hands) (HP:0001180) | 1.97652146 |
| 66 | Gastrointestinal atresia (HP:0002589) | 1.97106026 |
| 67 | Megalencephaly (HP:0001355) | 1.96974718 |
| 68 | Carpal bone hypoplasia (HP:0001498) | 1.96372270 |
| 69 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.95914049 |
| 70 | Abnormality of cochlea (HP:0000375) | 1.92972552 |
| 71 | Abnormal number of incisors (HP:0011064) | 1.92354125 |
| 72 | Preaxial hand polydactyly (HP:0001177) | 1.92237875 |
| 73 | Postnatal microcephaly (HP:0005484) | 1.92226285 |
| 74 | Renal hypoplasia (HP:0000089) | 1.91500982 |
| 75 | Renal cortical cysts (HP:0000803) | 1.90086239 |
| 76 | Septo-optic dysplasia (HP:0100842) | 1.87836298 |
| 77 | Adactyly (HP:0009776) | 1.85574808 |
| 78 | CNS demyelination (HP:0007305) | 1.84680209 |
| 79 | Tubular atrophy (HP:0000092) | 1.84357298 |
| 80 | Clubbing of toes (HP:0100760) | 1.82613306 |
| 81 | Narrow forehead (HP:0000341) | 1.81963414 |
| 82 | Abnormality of the preputium (HP:0100587) | 1.81663673 |
| 83 | Absent phalangeal crease (HP:0006109) | 1.81185596 |
| 84 | Postaxial hand polydactyly (HP:0001162) | 1.81174832 |
| 85 | Congenital primary aphakia (HP:0007707) | 1.80079622 |
| 86 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.80066698 |
| 87 | Sclerocornea (HP:0000647) | 1.78711326 |
| 88 | Sloping forehead (HP:0000340) | 1.78520208 |
| 89 | Postaxial foot polydactyly (HP:0001830) | 1.78373777 |
| 90 | Genital tract atresia (HP:0001827) | 1.77179001 |
| 91 | Agitation (HP:0000713) | 1.76618820 |
| 92 | Abnormality of the antihelix (HP:0009738) | 1.74901671 |
| 93 | Optic nerve hypoplasia (HP:0000609) | 1.74566780 |
| 94 | Abnormality of the duodenum (HP:0002246) | 1.74522468 |
| 95 | Unsteady gait (HP:0002317) | 1.73055897 |
| 96 | Gait imbalance (HP:0002141) | 1.72975225 |
| 97 | IgM deficiency (HP:0002850) | 1.72717035 |
| 98 | Anencephaly (HP:0002323) | 1.70519178 |
| 99 | Male pseudohermaphroditism (HP:0000037) | 1.70210851 |
| 100 | Abnormality of the carotid arteries (HP:0005344) | 1.69948560 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK1 | 9.64897480 |
| 2 | PRKCI | 2.90388996 |
| 3 | WNK3 | 2.52552984 |
| 4 | STK38L | 2.38575692 |
| 5 | BMPR2 | 2.37635766 |
| 6 | MARK1 | 2.26170133 |
| 7 | NEK1 | 2.08143591 |
| 8 | EIF2AK3 | 1.97998300 |
| 9 | FRK | 1.95034807 |
| 10 | MAP4K2 | 1.91802004 |
| 11 | MAPK13 | 1.87070331 |
| 12 | NUAK1 | 1.82277473 |
| 13 | CASK | 1.73250969 |
| 14 | BMPR1B | 1.67846569 |
| 15 | WEE1 | 1.64046695 |
| 16 | CDC7 | 1.62832798 |
| 17 | TNIK | 1.57289827 |
| 18 | PRKCG | 1.56256313 |
| 19 | CDK8 | 1.54122005 |
| 20 | MAP4K1 | 1.51608196 |
| 21 | BUB1 | 1.47364696 |
| 22 | MKNK2 | 1.42277692 |
| 23 | YES1 | 1.39952876 |
| 24 | PLK4 | 1.39325267 |
| 25 | CCNB1 | 1.36627062 |
| 26 | PKN1 | 1.36182840 |
| 27 | MAP3K4 | 1.29768377 |
| 28 | PRKCE | 1.28948210 |
| 29 | STK39 | 1.23689807 |
| 30 | BRSK1 | 1.13938765 |
| 31 | ADRBK2 | 1.09806233 |
| 32 | DMPK | 1.07489662 |
| 33 | BRSK2 | 1.05659097 |
| 34 | GRK1 | 0.99193866 |
| 35 | PLK3 | 0.96203900 |
| 36 | LIMK1 | 0.95325077 |
| 37 | MKNK1 | 0.94490562 |
| 38 | TRIM28 | 0.93278783 |
| 39 | WNK4 | 0.93054247 |
| 40 | PDPK1 | 0.92283624 |
| 41 | PLK2 | 0.89327968 |
| 42 | ZAK | 0.85929364 |
| 43 | SRPK1 | 0.85266769 |
| 44 | DYRK2 | 0.84651663 |
| 45 | PASK | 0.84314883 |
| 46 | NTRK2 | 0.80838736 |
| 47 | EIF2AK1 | 0.76677730 |
| 48 | PRKCZ | 0.76339703 |
| 49 | DAPK3 | 0.74109595 |
| 50 | INSRR | 0.74014886 |
| 51 | EPHA4 | 0.73446546 |
| 52 | PLK1 | 0.71417244 |
| 53 | CSNK1G2 | 0.71230025 |
| 54 | MAPKAPK3 | 0.71149674 |
| 55 | MAP2K7 | 0.67693195 |
| 56 | CSNK1G1 | 0.64298165 |
| 57 | PINK1 | 0.63873164 |
| 58 | CDK3 | 0.58399595 |
| 59 | CSNK1G3 | 0.58265021 |
| 60 | PRKD3 | 0.58132600 |
| 61 | STK24 | 0.56372049 |
| 62 | EPHB2 | 0.55959930 |
| 63 | TTK | 0.55588804 |
| 64 | ROCK1 | 0.54534013 |
| 65 | ATR | 0.51828954 |
| 66 | PDK2 | 0.46295731 |
| 67 | ACVR1B | 0.45983810 |
| 68 | PRKCB | 0.45944038 |
| 69 | PRKCD | 0.44928142 |
| 70 | PBK | 0.41085902 |
| 71 | CSNK2A1 | 0.40258064 |
| 72 | TGFBR1 | 0.39849662 |
| 73 | STK4 | 0.39350989 |
| 74 | VRK1 | 0.38304005 |
| 75 | ATM | 0.38228045 |
| 76 | EIF2AK2 | 0.38203372 |
| 77 | CLK1 | 0.38172671 |
| 78 | MINK1 | 0.37792053 |
| 79 | STK3 | 0.36900266 |
| 80 | PTK2B | 0.36717164 |
| 81 | PNCK | 0.36506100 |
| 82 | FGR | 0.35005245 |
| 83 | CHEK2 | 0.34757137 |
| 84 | CAMKK2 | 0.34566534 |
| 85 | TIE1 | 0.33415835 |
| 86 | CSNK1A1 | 0.32499829 |
| 87 | CSNK2A2 | 0.31906315 |
| 88 | CSNK1A1L | 0.31538490 |
| 89 | AURKB | 0.29797038 |
| 90 | CSNK1D | 0.29521023 |
| 91 | CHEK1 | 0.29151656 |
| 92 | BCR | 0.28991220 |
| 93 | CDC42BPA | 0.28850730 |
| 94 | RPS6KA5 | 0.27938806 |
| 95 | OXSR1 | 0.27662386 |
| 96 | CDK18 | 0.27231162 |
| 97 | PRKCQ | 0.26902572 |
| 98 | CDK15 | 0.26040829 |
| 99 | PRKACA | 0.25264212 |
| 100 | PAK3 | 0.25181146 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sulfur relay system_Homo sapiens_hsa04122 | 3.45370391 |
| 2 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.38728075 |
| 3 | Tyrosine metabolism_Homo sapiens_hsa00350 | 3.33042575 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.31787680 |
| 5 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.64126524 |
| 6 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.52368014 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.45405273 |
| 8 | RNA degradation_Homo sapiens_hsa03018 | 2.27523948 |
| 9 | Lysine degradation_Homo sapiens_hsa00310 | 2.21758785 |
| 10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.18216730 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.12262893 |
| 12 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.92192082 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 1.91850926 |
| 14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.67245085 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.66656227 |
| 16 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.64740116 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.63535569 |
| 18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.59356019 |
| 19 | Olfactory transduction_Homo sapiens_hsa04740 | 1.56863323 |
| 20 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.54654928 |
| 21 | RNA polymerase_Homo sapiens_hsa03020 | 1.54204632 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.54149196 |
| 23 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.50248457 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.43296010 |
| 25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.43137388 |
| 26 | Proteasome_Homo sapiens_hsa03050 | 1.41966088 |
| 27 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.31802463 |
| 28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.30300735 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.30221928 |
| 30 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.29838172 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.27279915 |
| 32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.24305265 |
| 33 | Basal transcription factors_Homo sapiens_hsa03022 | 1.19175826 |
| 34 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.18937701 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.17692980 |
| 36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.16772257 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.16254635 |
| 38 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15930990 |
| 39 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.08956272 |
| 40 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.08908868 |
| 41 | Alzheimers disease_Homo sapiens_hsa05010 | 1.08386352 |
| 42 | Cell cycle_Homo sapiens_hsa04110 | 1.06477852 |
| 43 | Spliceosome_Homo sapiens_hsa03040 | 1.03614194 |
| 44 | Axon guidance_Homo sapiens_hsa04360 | 1.02719808 |
| 45 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.00687835 |
| 46 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.99386238 |
| 47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.92739707 |
| 48 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.87957693 |
| 49 | Retinol metabolism_Homo sapiens_hsa00830 | 0.86050773 |
| 50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.85831844 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.83228039 |
| 52 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.82751590 |
| 53 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.82642675 |
| 54 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.80943737 |
| 55 | Mismatch repair_Homo sapiens_hsa03430 | 0.80122333 |
| 56 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.77103587 |
| 57 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.76034963 |
| 58 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.75392262 |
| 59 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.74981063 |
| 60 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.74881886 |
| 61 | Purine metabolism_Homo sapiens_hsa00230 | 0.73756086 |
| 62 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.73351824 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.71620783 |
| 64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.71579252 |
| 65 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.71548951 |
| 66 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.71276209 |
| 67 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.71010776 |
| 68 | Base excision repair_Homo sapiens_hsa03410 | 0.68585362 |
| 69 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.68295134 |
| 70 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.65633724 |
| 71 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.65350237 |
| 72 | Tight junction_Homo sapiens_hsa04530 | 0.64951618 |
| 73 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.63028233 |
| 74 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.63020834 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.59443820 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57469606 |
| 77 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.55919008 |
| 78 | Taste transduction_Homo sapiens_hsa04742 | 0.55115882 |
| 79 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.51554244 |
| 80 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.51263023 |
| 81 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.49772194 |
| 82 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.48569892 |
| 83 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46568199 |
| 84 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45474723 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.42854259 |
| 86 | Morphine addiction_Homo sapiens_hsa05032 | 0.42145745 |
| 87 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41514053 |
| 88 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.40668654 |
| 89 | Mineral absorption_Homo sapiens_hsa04978 | 0.39853943 |
| 90 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37354846 |
| 91 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.33271070 |
| 92 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.31832456 |
| 93 | Salivary secretion_Homo sapiens_hsa04970 | 0.31283248 |
| 94 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.30956980 |
| 95 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.30889165 |
| 96 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.30648174 |
| 97 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.28242885 |
| 98 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.28108515 |
| 99 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.26449479 |
| 100 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.26117209 |

