

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) | 9.85725768 |
| 2 | maturation of 5.8S rRNA (GO:0000460) | 9.58583482 |
| 3 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 9.25396800 |
| 4 | secretory granule organization (GO:0033363) | 8.84761572 |
| 5 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 8.02783768 |
| 6 | platelet formation (GO:0030220) | 7.54043379 |
| 7 | regulation of mitochondrial translation (GO:0070129) | 7.00980853 |
| 8 | cytochrome complex assembly (GO:0017004) | 6.62401505 |
| 9 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 5.81567951 |
| 10 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902230) | 5.52350130 |
| 11 | ribosomal small subunit biogenesis (GO:0042274) | 5.46832669 |
| 12 | regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) | 5.43119131 |
| 13 | fusion of sperm to egg plasma membrane (GO:0007342) | 5.42030308 |
| 14 | negative regulation of translational initiation (GO:0045947) | 5.32841971 |
| 15 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 5.30294122 |
| 16 | positive regulation of macrophage differentiation (GO:0045651) | 5.28551779 |
| 17 | myeloid cell development (GO:0061515) | 5.08785816 |
| 18 | pseudouridine synthesis (GO:0001522) | 4.78550131 |
| 19 | piRNA metabolic process (GO:0034587) | 4.59329649 |
| 20 | ribosomal small subunit assembly (GO:0000028) | 4.53205294 |
| 21 | T cell apoptotic process (GO:0070231) | 4.43420834 |
| 22 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902229) | 4.40383612 |
| 23 | plasma membrane fusion (GO:0045026) | 4.39829777 |
| 24 | positive regulation of fat cell differentiation (GO:0045600) | 4.33820289 |
| 25 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.16336310 |
| 26 | protein complex biogenesis (GO:0070271) | 4.14637419 |
| 27 | fibril organization (GO:0097435) | 4.02951249 |
| 28 | regulation of necrotic cell death (GO:0010939) | 3.98882054 |
| 29 | regulation of translation in response to stress (GO:0043555) | 3.97627508 |
| 30 | response to food (GO:0032094) | 3.96197981 |
| 31 | negative regulation of membrane potential (GO:0045837) | 3.95334311 |
| 32 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.92793375 |
| 33 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.92215724 |
| 34 | positive regulation of mast cell degranulation (GO:0043306) | 3.92215724 |
| 35 | lymphocyte apoptotic process (GO:0070227) | 3.90238235 |
| 36 | protein kinase B signaling (GO:0043491) | 3.89302176 |
| 37 | negative regulation of chemokine production (GO:0032682) | 3.81022991 |
| 38 | regulation of epidermal growth factor-activated receptor activity (GO:0007176) | 3.80329322 |
| 39 | regulation of B cell differentiation (GO:0045577) | 3.77879068 |
| 40 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.77110070 |
| 41 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.74538373 |
| 42 | viral transcription (GO:0019083) | 3.60993915 |
| 43 | cellular protein catabolic process (GO:0044257) | 3.56007807 |
| 44 | regulation of necroptotic process (GO:0060544) | 3.52292788 |
| 45 | lamellipodium assembly (GO:0030032) | 3.49777151 |
| 46 | regulation of signal transduction by p53 class mediator (GO:1901796) | 3.48364459 |
| 47 | translational termination (GO:0006415) | 3.44812592 |
| 48 | necroptotic process (GO:0070266) | 3.43746356 |
| 49 | regulation of memory T cell differentiation (GO:0043380) | 3.42351314 |
| 50 | erythrocyte maturation (GO:0043249) | 3.35769781 |
| 51 | respiratory chain complex IV assembly (GO:0008535) | 3.35083555 |
| 52 | glucose 6-phosphate metabolic process (GO:0051156) | 3.30317460 |
| 53 | positive regulation of translation (GO:0045727) | 3.27082796 |
| 54 | regulation of translational initiation (GO:0006446) | 3.25167605 |
| 55 | lamellipodium organization (GO:0097581) | 3.15426533 |
| 56 | positive regulation of mast cell activation (GO:0033005) | 3.08493679 |
| 57 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.07917145 |
| 58 | ubiquinone biosynthetic process (GO:0006744) | 3.07237155 |
| 59 | rRNA catabolic process (GO:0016075) | 3.05940571 |
| 60 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.05478621 |
| 61 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.05454842 |
| 62 | positive regulation of growth hormone secretion (GO:0060124) | 3.02085495 |
| 63 | positive regulation of response to DNA damage stimulus (GO:2001022) | 3.01742646 |
| 64 | oligodendrocyte development (GO:0014003) | 3.00761414 |
| 65 | regulation of macrophage differentiation (GO:0045649) | 3.00031070 |
| 66 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.95418294 |
| 67 | multicellular organism reproduction (GO:0032504) | 2.92440282 |
| 68 | cotranslational protein targeting to membrane (GO:0006613) | 2.92409378 |
| 69 | negative regulation of response to DNA damage stimulus (GO:2001021) | 2.92117774 |
| 70 | protein targeting to ER (GO:0045047) | 2.84001457 |
| 71 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.82790902 |
| 72 | leukocyte apoptotic process (GO:0071887) | 2.82061367 |
| 73 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.80752021 |
| 74 | ubiquinone metabolic process (GO:0006743) | 2.75146909 |
| 75 | nucleoside transmembrane transport (GO:1901642) | 2.74155105 |
| 76 | positive regulation of T cell apoptotic process (GO:0070234) | 2.71695812 |
| 77 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.71435589 |
| 78 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.71435589 |
| 79 | detection of light stimulus involved in visual perception (GO:0050908) | 2.70632865 |
| 80 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.70632865 |
| 81 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 2.69982863 |
| 82 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.69378057 |
| 83 | neural tube formation (GO:0001841) | 2.68517279 |
| 84 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.64823587 |
| 85 | protein localization to endoplasmic reticulum (GO:0070972) | 2.64373595 |
| 86 | translational initiation (GO:0006413) | 2.63099827 |
| 87 | rRNA modification (GO:0000154) | 2.61258812 |
| 88 | protein insertion into membrane (GO:0051205) | 2.61055500 |
| 89 | leukotriene biosynthetic process (GO:0019370) | 2.60539980 |
| 90 | translational elongation (GO:0006414) | 2.60337002 |
| 91 | necrotic cell death (GO:0070265) | 2.58760278 |
| 92 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 2.56855948 |
| 93 | cellular protein complex disassembly (GO:0043624) | 2.56478882 |
| 94 | RNA localization (GO:0006403) | 15.9024397 |
| 95 | signal complex assembly (GO:0007172) | 13.4935523 |
| 96 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 11.9671413 |
| 97 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 11.7453904 |
| 98 | megakaryocyte development (GO:0035855) | 10.5845393 |
| 99 | positive regulation of translational initiation (GO:0045948) | 10.3479850 |
| 100 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 10.0002963 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 7.93015042 |
| 2 | TP53_16413492_ChIP-PET_HCT116_Human | 3.53764851 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.32814115 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.09075317 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.90914689 |
| 6 | EGR1_19032775_ChIP-ChIP_M12_Human | 2.74413675 |
| 7 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.73633617 |
| 8 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.43275329 |
| 9 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.22429934 |
| 10 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.20259973 |
| 11 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.13625512 |
| 12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.06742448 |
| 13 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.05102152 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.99340159 |
| 15 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.96248499 |
| 16 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.95001693 |
| 17 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.93329042 |
| 18 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.86365809 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.86345092 |
| 20 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.83091498 |
| 21 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.77822170 |
| 22 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.76577782 |
| 23 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.76508116 |
| 24 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.74304647 |
| 25 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.73909857 |
| 26 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.70527564 |
| 27 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.66606771 |
| 28 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.61482596 |
| 29 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.61467638 |
| 30 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.59903281 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.59571736 |
| 32 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.54476975 |
| 33 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.53923211 |
| 34 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.51648148 |
| 35 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.46305920 |
| 36 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.46088241 |
| 37 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.46088241 |
| 38 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.45251361 |
| 39 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.44872562 |
| 40 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.43165975 |
| 41 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.43093324 |
| 42 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.41318407 |
| 43 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.36937192 |
| 44 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.36808008 |
| 45 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.33383038 |
| 46 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31663957 |
| 47 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.31062949 |
| 48 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.30765141 |
| 49 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.30013257 |
| 50 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.28797572 |
| 51 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.27951246 |
| 52 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.27878093 |
| 53 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.26941123 |
| 54 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.26897055 |
| 55 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.25502294 |
| 56 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.25030319 |
| 57 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.24018591 |
| 58 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.22456933 |
| 59 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22456933 |
| 60 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.21484895 |
| 61 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.19584356 |
| 62 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.14610187 |
| 63 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.12296829 |
| 64 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.11447674 |
| 65 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.09474172 |
| 66 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.09299900 |
| 67 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 1.09115817 |
| 68 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.08682399 |
| 69 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08123680 |
| 70 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.08023207 |
| 71 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.06718436 |
| 72 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.06700441 |
| 73 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.06502563 |
| 74 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.05870925 |
| 75 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04732749 |
| 76 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.04652156 |
| 77 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.03961052 |
| 78 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.03165109 |
| 79 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.03036417 |
| 80 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02306964 |
| 81 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.01204964 |
| 82 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.00770284 |
| 83 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00462067 |
| 84 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.00284385 |
| 85 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.98879685 |
| 86 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.96372696 |
| 87 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.95172875 |
| 88 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.94664730 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.94255248 |
| 90 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.93377930 |
| 91 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92244773 |
| 92 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.91931318 |
| 93 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.91427763 |
| 94 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.91011171 |
| 95 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.90874921 |
| 96 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.89664079 |
| 97 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.89277305 |
| 98 | STAT3_23295773_ChIP-Seq_U87_Human | 0.88421174 |
| 99 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.87536118 |
| 100 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.86982820 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 6.30037789 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.50894131 |
| 3 | MP0004145_abnormal_muscle_electrophysio | 3.45569241 |
| 4 | MP0004147_increased_porphyrin_level | 3.02364220 |
| 5 | MP0000372_irregular_coat_pigmentation | 2.99987356 |
| 6 | MP0001348_abnormal_lacrimal_gland | 2.91316859 |
| 7 | MP0005410_abnormal_fertilization | 2.64312254 |
| 8 | MP0001661_extended_life_span | 2.50479306 |
| 9 | MP0002163_abnormal_gland_morphology | 2.40070263 |
| 10 | MP0005503_abnormal_tendon_morphology | 2.32889887 |
| 11 | MP0002102_abnormal_ear_morphology | 2.31212439 |
| 12 | MP0002938_white_spotting | 2.30037270 |
| 13 | MP0004130_abnormal_muscle_cell | 2.28520711 |
| 14 | MP0003880_abnormal_central_pattern | 2.08713885 |
| 15 | MP0005083_abnormal_biliary_tract | 2.05918687 |
| 16 | MP0006035_abnormal_mitochondrial_morpho | 1.99786465 |
| 17 | MP0005379_endocrine/exocrine_gland_phen | 1.99510510 |
| 18 | MP0005645_abnormal_hypothalamus_physiol | 1.96942104 |
| 19 | MP0003195_calcinosis | 1.92036938 |
| 20 | MP0008789_abnormal_olfactory_epithelium | 1.91056326 |
| 21 | MP0000462_abnormal_digestive_system | 1.80038064 |
| 22 | MP0005377_hearing/vestibular/ear_phenot | 1.75487790 |
| 23 | MP0003878_abnormal_ear_physiology | 1.75487790 |
| 24 | MP0002277_abnormal_respiratory_mucosa | 1.67577189 |
| 25 | MP0002095_abnormal_skin_pigmentation | 1.67248209 |
| 26 | MP0003136_yellow_coat_color | 1.67226191 |
| 27 | MP0000534_abnormal_ureter_morphology | 1.62218815 |
| 28 | MP0010030_abnormal_orbit_morphology | 1.56666860 |
| 29 | MP0005174_abnormal_tail_pigmentation | 1.53646446 |
| 30 | MP0004142_abnormal_muscle_tone | 1.50874754 |
| 31 | MP0000579_abnormal_nail_morphology | 1.47147081 |
| 32 | MP0009046_muscle_twitch | 1.46151764 |
| 33 | MP0005084_abnormal_gallbladder_morpholo | 1.42816768 |
| 34 | MP0005394_taste/olfaction_phenotype | 1.41053740 |
| 35 | MP0005499_abnormal_olfactory_system | 1.41053740 |
| 36 | MP0002160_abnormal_reproductive_system | 1.36871276 |
| 37 | MP0001664_abnormal_digestion | 1.33728209 |
| 38 | MP0005187_abnormal_penis_morphology | 1.31091184 |
| 39 | MP0004885_abnormal_endolymph | 1.28996286 |
| 40 | MP0003787_abnormal_imprinting | 1.27008427 |
| 41 | MP0002837_dystrophic_cardiac_calcinosis | 1.26514502 |
| 42 | MP0005253_abnormal_eye_physiology | 1.25542087 |
| 43 | MP0005551_abnormal_eye_electrophysiolog | 1.25043219 |
| 44 | MP0003436_decreased_susceptibility_to | 1.24081593 |
| 45 | MP0002876_abnormal_thyroid_physiology | 1.22415881 |
| 46 | MP0002736_abnormal_nociception_after | 1.18393540 |
| 47 | MP0009250_abnormal_appendicular_skeleto | 1.17531960 |
| 48 | MP0006072_abnormal_retinal_apoptosis | 1.15827372 |
| 49 | MP0000751_myopathy | 1.14653353 |
| 50 | MP0000631_abnormal_neuroendocrine_gland | 1.13292263 |
| 51 | MP0001986_abnormal_taste_sensitivity | 1.11611743 |
| 52 | MP0000015_abnormal_ear_pigmentation | 1.10286844 |
| 53 | MP0009764_decreased_sensitivity_to | 1.09341504 |
| 54 | MP0003937_abnormal_limbs/digits/tail_de | 1.08385175 |
| 55 | MP0002184_abnormal_innervation | 1.06347477 |
| 56 | MP0009745_abnormal_behavioral_response | 1.00867505 |
| 57 | MP0002272_abnormal_nervous_system | 0.99839958 |
| 58 | MP0001502_abnormal_circadian_rhythm | 0.99376759 |
| 59 | MP0003137_abnormal_impulse_conducting | 0.98870835 |
| 60 | MP0008775_abnormal_heart_ventricle | 0.97490948 |
| 61 | MP0000639_abnormal_adrenal_gland | 0.96300793 |
| 62 | MP0005389_reproductive_system_phenotype | 0.95593418 |
| 63 | MP0004215_abnormal_myocardial_fiber | 0.93543228 |
| 64 | MP0002557_abnormal_social/conspecific_i | 0.93092803 |
| 65 | MP0005197_abnormal_uvea_morphology | 0.92726848 |
| 66 | MP0003718_maternal_effect | 0.92135720 |
| 67 | MP0002971_abnormal_brown_adipose | 0.89312694 |
| 68 | MP0009379_abnormal_foot_pigmentation | 0.86974113 |
| 69 | MP0001486_abnormal_startle_reflex | 0.86833446 |
| 70 | MP0008004_abnormal_stomach_pH | 0.86386560 |
| 71 | MP0002108_abnormal_muscle_morphology | 0.85875637 |
| 72 | MP0003635_abnormal_synaptic_transmissio | 0.85558533 |
| 73 | MP0001542_abnormal_bone_strength | 0.83460339 |
| 74 | MP0003122_maternal_imprinting | 0.82639259 |
| 75 | MP0003959_abnormal_lean_body | 0.81322263 |
| 76 | MP0003315_abnormal_perineum_morphology | 0.80782537 |
| 77 | MP0002752_abnormal_somatic_nervous | 0.77498346 |
| 78 | MP0002233_abnormal_nose_morphology | 0.76029909 |
| 79 | MP0004957_abnormal_blastocyst_morpholog | 0.75498187 |
| 80 | MP0001293_anophthalmia | 0.75473696 |
| 81 | MP0005171_absent_coat_pigmentation | 0.75255481 |
| 82 | MP0001501_abnormal_sleep_pattern | 0.72661317 |
| 83 | MP0005195_abnormal_posterior_eye | 0.71165656 |
| 84 | MP0002148_abnormal_hypersensitivity_rea | 0.70985590 |
| 85 | MP0005636_abnormal_mineral_homeostasis | 0.70867721 |
| 86 | MP0006276_abnormal_autonomic_nervous | 0.69291565 |
| 87 | MP0005423_abnormal_somatic_nervous | 0.69192215 |
| 88 | MP0001324_abnormal_eye_pigmentation | 0.68595778 |
| 89 | MP0002822_catalepsy | 0.67741752 |
| 90 | MP0000778_abnormal_nervous_system | 0.67058527 |
| 91 | MP0009384_cardiac_valve_regurgitation | 0.66176210 |
| 92 | MP0005646_abnormal_pituitary_gland | 0.64867455 |
| 93 | MP0008872_abnormal_physiological_respon | 0.64616406 |
| 94 | MP0002734_abnormal_mechanical_nocicepti | 0.63934850 |
| 95 | MP0005408_hypopigmentation | 0.63721186 |
| 96 | MP0001968_abnormal_touch/_nociception | 0.62955906 |
| 97 | MP0001727_abnormal_embryo_implantation | 0.61836702 |
| 98 | MP0003936_abnormal_reproductive_system | 0.60171745 |
| 99 | MP0008995_early_reproductive_senescence | 0.59932408 |
| 100 | MP0002751_abnormal_autonomic_nervous | 0.59727619 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cerebral hypomyelination (HP:0006808) | 7.72152681 |
| 2 | Concave nail (HP:0001598) | 5.33019420 |
| 3 | Premature ovarian failure (HP:0008209) | 4.31277511 |
| 4 | Agitation (HP:0000713) | 4.02656586 |
| 5 | Delusions (HP:0000746) | 3.87087933 |
| 6 | Aplasia of the musculature (HP:0100854) | 3.86257697 |
| 7 | CNS hypomyelination (HP:0003429) | 3.79137270 |
| 8 | Prolonged neonatal jaundice (HP:0006579) | 3.77604241 |
| 9 | Bifid tongue (HP:0010297) | 3.60966335 |
| 10 | Oral leukoplakia (HP:0002745) | 3.57410086 |
| 11 | Aplastic anemia (HP:0001915) | 3.44750967 |
| 12 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 3.34266982 |
| 13 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 3.31408272 |
| 14 | Personality changes (HP:0000751) | 3.27546278 |
| 15 | Postnatal microcephaly (HP:0005484) | 3.26355023 |
| 16 | Secondary amenorrhea (HP:0000869) | 3.24940975 |
| 17 | Reticulocytosis (HP:0001923) | 3.09987303 |
| 18 | Pendular nystagmus (HP:0012043) | 3.09906750 |
| 19 | Macrocytic anemia (HP:0001972) | 3.05825156 |
| 20 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.96322911 |
| 21 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.96042946 |
| 22 | Mesomelia (HP:0003027) | 2.92464499 |
| 23 | Hypoplasia of the uterus (HP:0000013) | 2.88381279 |
| 24 | Small epiphyses (HP:0010585) | 2.82417850 |
| 25 | Adrenal hypoplasia (HP:0000835) | 2.82235914 |
| 26 | Rib fusion (HP:0000902) | 2.76976540 |
| 27 | Pallor (HP:0000980) | 2.72157550 |
| 28 | Unsteady gait (HP:0002317) | 2.64664568 |
| 29 | Septo-optic dysplasia (HP:0100842) | 2.63026346 |
| 30 | Abnormality of reticulocytes (HP:0004312) | 2.62053473 |
| 31 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.57838923 |
| 32 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.51882781 |
| 33 | Increased corneal curvature (HP:0100692) | 2.49662380 |
| 34 | Keratoconus (HP:0000563) | 2.49662380 |
| 35 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.48677519 |
| 36 | Testicular atrophy (HP:0000029) | 2.48590776 |
| 37 | Short tibia (HP:0005736) | 2.47768904 |
| 38 | Hypercortisolism (HP:0001578) | 2.44730553 |
| 39 | Absent phalangeal crease (HP:0006109) | 2.43922921 |
| 40 | Alveolar cell carcinoma (HP:0006519) | 2.41549956 |
| 41 | Short middle phalanx of the 5th finger (HP:0004220) | 2.41383054 |
| 42 | Renal tubular acidosis (HP:0001947) | 2.39545881 |
| 43 | Hyperventilation (HP:0002883) | 2.38722884 |
| 44 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.36444140 |
| 45 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.36442364 |
| 46 | Pigmentary retinal degeneration (HP:0001146) | 2.34524830 |
| 47 | Short femoral neck (HP:0100864) | 2.34440235 |
| 48 | Abnormal number of erythroid precursors (HP:0012131) | 2.32204782 |
| 49 | Anophthalmia (HP:0000528) | 2.30252188 |
| 50 | IgM deficiency (HP:0002850) | 2.29068715 |
| 51 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.27267749 |
| 52 | Delayed epiphyseal ossification (HP:0002663) | 2.25486500 |
| 53 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.17691110 |
| 54 | Sudden death (HP:0001699) | 2.16277020 |
| 55 | Irregular epiphyses (HP:0010582) | 2.14784195 |
| 56 | Optic nerve hypoplasia (HP:0000609) | 2.14554297 |
| 57 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.13550840 |
| 58 | Abnormality of cochlea (HP:0000375) | 2.13272889 |
| 59 | Hepatoblastoma (HP:0002884) | 2.11292976 |
| 60 | Dyskinesia (HP:0100660) | 2.09055408 |
| 61 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.08287276 |
| 62 | Renal tubular dysfunction (HP:0000124) | 2.07447643 |
| 63 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.05707297 |
| 64 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.04590950 |
| 65 | Morphological abnormality of the inner ear (HP:0011390) | 2.01315050 |
| 66 | Truncal obesity (HP:0001956) | 1.99598179 |
| 67 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.98799367 |
| 68 | CNS demyelination (HP:0007305) | 1.97986825 |
| 69 | Severe muscular hypotonia (HP:0006829) | 1.96829575 |
| 70 | Osteomalacia (HP:0002749) | 1.94183008 |
| 71 | Congenital stationary night blindness (HP:0007642) | 1.93845759 |
| 72 | Abnormal finger flexion creases (HP:0006143) | 1.93557439 |
| 73 | Hypomagnesemia (HP:0002917) | 1.91738783 |
| 74 | Striae distensae (HP:0001065) | 1.91559725 |
| 75 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.87404931 |
| 76 | Abnormal ciliary motility (HP:0012262) | 1.87283927 |
| 77 | Status epilepticus (HP:0002133) | 1.86599877 |
| 78 | Pterygium (HP:0001059) | 1.86278055 |
| 79 | Bile duct proliferation (HP:0001408) | 1.85528421 |
| 80 | Abnormal biliary tract physiology (HP:0012439) | 1.85528421 |
| 81 | Hyperglycinemia (HP:0002154) | 1.84729735 |
| 82 | Submucous cleft hard palate (HP:0000176) | 1.83037422 |
| 83 | Renal cortical cysts (HP:0000803) | 1.81741913 |
| 84 | Synostosis of carpal bones (HP:0005048) | 1.81419226 |
| 85 | Ulnar deviation of the wrist (HP:0003049) | 1.81354452 |
| 86 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.80538984 |
| 87 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.79983161 |
| 88 | Type 2 muscle fiber atrophy (HP:0003554) | 1.77477012 |
| 89 | Aplasia/hypoplasia of the femur (HP:0005613) | 1.76747462 |
| 90 | Fibular hypoplasia (HP:0003038) | 1.75782981 |
| 91 | Depressed nasal ridge (HP:0000457) | 1.75460766 |
| 92 | Increased hepatocellular lipid droplets (HP:0006565) | 1.74511194 |
| 93 | Abnormal hemoglobin (HP:0011902) | 1.73000729 |
| 94 | Abnormal number of incisors (HP:0011064) | 1.71852602 |
| 95 | Restlessness (HP:0000711) | 1.70707581 |
| 96 | Facial diplegia (HP:0001349) | 1.70463280 |
| 97 | Colon cancer (HP:0003003) | 1.69592202 |
| 98 | Renal Fanconi syndrome (HP:0001994) | 1.67771103 |
| 99 | Neoplasm of the adrenal cortex (HP:0100641) | 1.66839943 |
| 100 | Asplenia (HP:0001746) | 1.66785551 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PRKCI | 4.13990843 |
| 2 | BMPR2 | 4.07531997 |
| 3 | MAP4K1 | 2.04000149 |
| 4 | PDPK1 | 2.01095993 |
| 5 | RIPK1 | 14.0984706 |
| 6 | PRKCG | 1.86234754 |
| 7 | DAPK3 | 1.73414295 |
| 8 | NEK1 | 1.61933112 |
| 9 | YES1 | 1.40484946 |
| 10 | PRKCE | 1.26230845 |
| 11 | FRK | 1.26147370 |
| 12 | MAPKAPK3 | 1.20876520 |
| 13 | PRKCZ | 1.15209345 |
| 14 | EIF2AK3 | 1.04483057 |
| 15 | PASK | 1.02626630 |
| 16 | EPHA4 | 0.94520842 |
| 17 | WNK3 | 0.94405911 |
| 18 | STK38L | 0.91409236 |
| 19 | PRKCD | 0.87937880 |
| 20 | STK24 | 0.87634310 |
| 21 | CASK | 0.83824894 |
| 22 | WNK4 | 0.79924878 |
| 23 | PIK3CA | 0.76916026 |
| 24 | TRIM28 | 0.75277741 |
| 25 | FGR | 0.69425872 |
| 26 | STK38 | 0.60072199 |
| 27 | MAP2K7 | 0.59425749 |
| 28 | MAP3K4 | 0.57789237 |
| 29 | STK39 | 0.56757529 |
| 30 | TIE1 | 0.55420826 |
| 31 | INSRR | 0.54560146 |
| 32 | MARK1 | 0.54523963 |
| 33 | GRK1 | 0.53765007 |
| 34 | FLT3 | 0.51353933 |
| 35 | WEE1 | 0.51168242 |
| 36 | BCR | 0.49686905 |
| 37 | PTK2 | 0.48813255 |
| 38 | PRKCB | 0.47801408 |
| 39 | ZAK | 0.44221928 |
| 40 | OXSR1 | 0.42736057 |
| 41 | MUSK | 0.42666280 |
| 42 | MTOR | 0.41822362 |
| 43 | MYLK | 0.41409859 |
| 44 | NUAK1 | 0.38405344 |
| 45 | OBSCN | 0.38254055 |
| 46 | MAP4K2 | 0.37734099 |
| 47 | PRKCQ | 0.36279323 |
| 48 | CDK15 | 0.34287898 |
| 49 | TNIK | 0.33856335 |
| 50 | NTRK3 | 0.33441370 |
| 51 | MAPK10 | 0.33224472 |
| 52 | IKBKB | 0.33180108 |
| 53 | FYN | 0.33081461 |
| 54 | CDK18 | 0.32917535 |
| 55 | ILK | 0.32046231 |
| 56 | DYRK2 | 0.31605950 |
| 57 | DAPK1 | 0.31260885 |
| 58 | CSK | 0.31058333 |
| 59 | TRIB3 | 0.30569815 |
| 60 | ADRBK2 | 0.30364810 |
| 61 | SRC | 0.29620749 |
| 62 | PKN1 | 0.29231627 |
| 63 | CDK11A | 0.28345601 |
| 64 | CSNK2A2 | 0.28242174 |
| 65 | CSNK2A1 | 0.27766768 |
| 66 | DMPK | 0.27541023 |
| 67 | MAPK13 | 0.27365669 |
| 68 | PTK2B | 0.26955911 |
| 69 | CSNK1A1 | 0.26041367 |
| 70 | CDK14 | 0.25163854 |
| 71 | EPHB2 | 0.24907309 |
| 72 | STK4 | 0.24449756 |
| 73 | PDK2 | 0.23240650 |
| 74 | NTRK1 | 0.22157641 |
| 75 | MAP3K12 | 0.22111646 |
| 76 | CAMK2A | 0.22097324 |
| 77 | MAPK15 | 0.21995857 |
| 78 | NTRK2 | 0.18855131 |
| 79 | PAK3 | 0.17689260 |
| 80 | PRKCA | 0.17013314 |
| 81 | ERBB4 | 0.15107113 |
| 82 | BMPR1B | 0.14958938 |
| 83 | MET | 0.14849925 |
| 84 | LCK | 0.14153519 |
| 85 | BRSK2 | 0.13918171 |
| 86 | CAMKK1 | 0.13622243 |
| 87 | PRKACA | 0.13402553 |
| 88 | FGFR1 | 0.13359375 |
| 89 | CCNB1 | 0.12875645 |
| 90 | AKT1 | 0.12513783 |
| 91 | PRKD1 | 0.12363485 |
| 92 | EPHB1 | 0.12254781 |
| 93 | ROCK1 | 0.11421680 |
| 94 | PLK4 | 0.11094120 |
| 95 | EPHA2 | 0.11080758 |
| 96 | CSNK1G1 | 0.11053182 |
| 97 | CSNK1G3 | 0.10606772 |
| 98 | IGF1R | 0.10034688 |
| 99 | RPS6KA5 | 0.09993985 |
| 100 | MINK1 | 0.09457894 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Tyrosine metabolism_Homo sapiens_hsa00350 | 5.60019356 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 4.53441746 |
| 3 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.27447680 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.15814368 |
| 5 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.82780317 |
| 6 | ErbB signaling pathway_Homo sapiens_hsa04012 | 2.67339025 |
| 7 | Lysine degradation_Homo sapiens_hsa00310 | 2.37389030 |
| 8 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 2.16156327 |
| 9 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.98905902 |
| 10 | RNA degradation_Homo sapiens_hsa03018 | 1.98681584 |
| 11 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.94887243 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.89312051 |
| 13 | Olfactory transduction_Homo sapiens_hsa04740 | 1.87343380 |
| 14 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.78006478 |
| 15 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.73338050 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.70478549 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.70134133 |
| 18 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.64487795 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.64270932 |
| 20 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.63148598 |
| 21 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.57293600 |
| 22 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.51721332 |
| 23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.47566840 |
| 24 | Tight junction_Homo sapiens_hsa04530 | 1.41943891 |
| 25 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.35420602 |
| 26 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.34144020 |
| 27 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.25371557 |
| 28 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.18290066 |
| 29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.14578528 |
| 30 | Insulin resistance_Homo sapiens_hsa04931 | 1.13532955 |
| 31 | Parkinsons disease_Homo sapiens_hsa05012 | 1.06306778 |
| 32 | Axon guidance_Homo sapiens_hsa04360 | 1.05764304 |
| 33 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.02761595 |
| 34 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.97172388 |
| 35 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.97162303 |
| 36 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.91934376 |
| 37 | Nicotine addiction_Homo sapiens_hsa05033 | 0.91810753 |
| 38 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.91766288 |
| 39 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.90517458 |
| 40 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.87687657 |
| 41 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.87001241 |
| 42 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.86713038 |
| 43 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.84738624 |
| 44 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.84343852 |
| 45 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82719832 |
| 46 | Mineral absorption_Homo sapiens_hsa04978 | 0.82687388 |
| 47 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.82033330 |
| 48 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.77069808 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.76198963 |
| 50 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.76132128 |
| 51 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74566115 |
| 52 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.74377693 |
| 53 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.70341585 |
| 54 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.70298395 |
| 55 | Huntingtons disease_Homo sapiens_hsa05016 | 0.67120770 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.65987878 |
| 57 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.65877717 |
| 58 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.64785674 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.64116065 |
| 60 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.61849890 |
| 61 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.58901868 |
| 62 | Asthma_Homo sapiens_hsa05310 | 0.58706684 |
| 63 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.57877585 |
| 64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.57294760 |
| 65 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.56960865 |
| 66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56933046 |
| 67 | RNA transport_Homo sapiens_hsa03013 | 0.55281082 |
| 68 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.53717940 |
| 69 | Salivary secretion_Homo sapiens_hsa04970 | 0.53672725 |
| 70 | Morphine addiction_Homo sapiens_hsa05032 | 0.52003403 |
| 71 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51573736 |
| 72 | RNA polymerase_Homo sapiens_hsa03020 | 0.51272087 |
| 73 | Malaria_Homo sapiens_hsa05144 | 0.51076437 |
| 74 | Alzheimers disease_Homo sapiens_hsa05010 | 0.50711515 |
| 75 | Insulin secretion_Homo sapiens_hsa04911 | 0.50159670 |
| 76 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.47812704 |
| 77 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.45479822 |
| 78 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.44009402 |
| 79 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.43585466 |
| 80 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.43584568 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.41724760 |
| 82 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.41674189 |
| 83 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.40847353 |
| 84 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.34685704 |
| 85 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.34587006 |
| 86 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34435294 |
| 87 | Taste transduction_Homo sapiens_hsa04742 | 0.34089363 |
| 88 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.33508091 |
| 89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.31725429 |
| 90 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.31657441 |
| 91 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.29003142 |
| 92 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.28067855 |
| 93 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.27782822 |
| 94 | Bile secretion_Homo sapiens_hsa04976 | 0.27510183 |
| 95 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.24887930 |
| 96 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.24556090 |
| 97 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.24077769 |
| 98 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.23980575 |
| 99 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.23022219 |
| 100 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.22946334 |

