SNRPGP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)9.27312912
2cytidine metabolic process (GO:0046087)8.84124532
3cytidine catabolic process (GO:0006216)8.84124532
4cytidine deamination (GO:0009972)8.84124532
5regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450918.60910015
6pyrimidine ribonucleoside catabolic process (GO:0046133)7.68400486
7regulation of chronic inflammatory response (GO:0002676)6.49755364
8mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.31549434
9energy coupled proton transport, down electrochemical gradient (GO:0015985)4.89761834
10ATP synthesis coupled proton transport (GO:0015986)4.89761834
11negative regulation of B cell proliferation (GO:0030889)4.64005353
12cellular response to interferon-beta (GO:0035458)4.60162829
13regulation of regulatory T cell differentiation (GO:0045589)4.58355567
14positive regulation of inflammatory response to antigenic stimulus (GO:0002863)4.56713149
15tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.27528582
16RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.27528582
17proteasome assembly (GO:0043248)4.13098434
18DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.06311562
19regulation of cellular amino acid metabolic process (GO:0006521)4.01087336
20chaperone-mediated protein transport (GO:0072321)3.99602836
21intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.96764940
22signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.96764940
23positive regulation of humoral immune response (GO:0002922)3.95710259
24establishment of protein localization to mitochondrial membrane (GO:0090151)3.94049932
25signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.93435148
26signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.93435148
27signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.93435148
28mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.92329362
29maturation of 5.8S rRNA (GO:0000460)3.80018259
30regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.79063570
31signal transduction involved in DNA damage checkpoint (GO:0072422)3.74558928
32signal transduction involved in DNA integrity checkpoint (GO:0072401)3.74558928
33response to interferon-beta (GO:0035456)3.73276360
34respiratory electron transport chain (GO:0022904)3.72742734
35negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.72618443
36ribonucleoprotein complex disassembly (GO:0032988)3.70545196
37signal transduction involved in cell cycle checkpoint (GO:0072395)3.68875189
38electron transport chain (GO:0022900)3.63045656
39negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.59789454
40negative regulation of ligase activity (GO:0051352)3.59789454
41organelle disassembly (GO:1903008)3.59108163
42antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.55773303
43lymphoid progenitor cell differentiation (GO:0002320)3.51852502
44regulation of inflammatory response to antigenic stimulus (GO:0002861)3.48778345
45positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.48326618
46nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.37569482
47regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.36511538
48antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.34416344
49positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.34024664
50protein complex biogenesis (GO:0070271)3.30733927
51exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.30716733
52pteridine-containing compound biosynthetic process (GO:0042559)3.23631161
53positive regulation of cell cycle arrest (GO:0071158)3.18867778
54negative regulation of B cell activation (GO:0050869)3.16931659
55pyrimidine nucleoside catabolic process (GO:0046135)3.13370215
56AMP metabolic process (GO:0046033)3.08794592
57positive regulation of interleukin-1 beta secretion (GO:0050718)3.08580291
58transcription elongation from RNA polymerase I promoter (GO:0006362)3.06946193
59anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.03032793
60negative regulation of growth of symbiont in host (GO:0044130)2.99375547
61negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.99375547
62modulation of growth of symbiont involved in interaction with host (GO:0044144)2.99375547
63regulation of growth of symbiont in host (GO:0044126)2.99375547
64mitochondrial respiratory chain complex assembly (GO:0033108)2.98803522
65positive regulation of ligase activity (GO:0051351)2.97130601
66CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.95172732
67positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.94468023
68regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.92779804
69L-phenylalanine catabolic process (GO:0006559)2.92763937
70erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.92763937
71aromatic amino acid family catabolic process (GO:0009074)2.91340828
72maturation of SSU-rRNA (GO:0030490)2.90977835
73positive regulation of interleukin-1 secretion (GO:0050716)2.90420592
74anterograde synaptic vesicle transport (GO:0048490)2.90091089
75tryptophan catabolic process (GO:0006569)2.90075841
76indole-containing compound catabolic process (GO:0042436)2.90075841
77indolalkylamine catabolic process (GO:0046218)2.90075841
78negative regulation of acute inflammatory response (GO:0002674)2.89410749
79DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.88293257
80nucleotide transmembrane transport (GO:1901679)2.86516520
81regulation of cellular amine metabolic process (GO:0033238)2.86485379
82rRNA transcription (GO:0009303)2.85691906
83regulation of interleukin-1 beta secretion (GO:0050706)2.84309458
84termination of RNA polymerase III transcription (GO:0006386)2.83261805
85transcription elongation from RNA polymerase III promoter (GO:0006385)2.83261805
86ribosomal small subunit assembly (GO:0000028)2.81728739
87lymphocyte costimulation (GO:0031294)2.81184889
88protein neddylation (GO:0045116)2.79767141
89lymph node development (GO:0048535)2.75585702
90oxidative phosphorylation (GO:0006119)2.75033676
91NADH dehydrogenase complex assembly (GO:0010257)2.72666387
92mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.72666387
93mitochondrial respiratory chain complex I assembly (GO:0032981)2.72666387
94negative regulation of cell cycle G1/S phase transition (GO:1902807)2.71383758
95negative regulation of G1/S transition of mitotic cell cycle (GO:2000134)2.71383758
96T cell costimulation (GO:0031295)2.71328339
97positive regulation of immunoglobulin mediated immune response (GO:0002891)2.70922884
98positive regulation of B cell mediated immunity (GO:0002714)2.70922884
99cellular response to interleukin-15 (GO:0071350)2.70643982
100regulation of ligase activity (GO:0051340)2.69806825

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human6.40189872
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.76107579
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.55103803
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.03392416
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.99506568
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.03358363
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.95066904
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.93459788
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.67905782
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.66784686
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.60325985
12VDR_23849224_ChIP-Seq_CD4+_Human2.54247204
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.42628193
14VDR_22108803_ChIP-Seq_LS180_Human2.39349196
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.36084831
16FLI1_27457419_Chip-Seq_LIVER_Mouse2.30821784
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.16351045
18ELK1_19687146_ChIP-ChIP_HELA_Human2.14931243
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.10556482
20FOXP3_21729870_ChIP-Seq_TREG_Human2.09620884
21PCGF2_27294783_Chip-Seq_ESCs_Mouse2.05118954
22MYC_18555785_ChIP-Seq_MESCs_Mouse2.00636906
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.00463456
24EWS_26573619_Chip-Seq_HEK293_Human1.90826651
25CREB1_15753290_ChIP-ChIP_HEK293T_Human1.81055475
26IRF1_19129219_ChIP-ChIP_H3396_Human1.80351582
27CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.76667874
28NOTCH1_21737748_ChIP-Seq_TLL_Human1.73975650
29ZNF274_21170338_ChIP-Seq_K562_Hela1.67301753
30IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.65248316
31TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58809241
32SUZ12_27294783_Chip-Seq_NPCs_Mouse1.58231296
33SRF_21415370_ChIP-Seq_HL-1_Mouse1.52176507
34FOXA1_25329375_ChIP-Seq_VCAP_Human1.51769091
35FOXA1_27270436_Chip-Seq_PROSTATE_Human1.51769091
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.48813962
37RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48387491
38IGF1R_20145208_ChIP-Seq_DFB_Human1.48116000
39PADI4_21655091_ChIP-ChIP_MCF-7_Human1.45600523
40TP53_22573176_ChIP-Seq_HFKS_Human1.42149163
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38202347
42NANOG_19829295_ChIP-Seq_ESCs_Human1.35733247
43SOX2_19829295_ChIP-Seq_ESCs_Human1.35733247
44MYC_18358816_ChIP-ChIP_MESCs_Mouse1.35559615
45AR_20517297_ChIP-Seq_VCAP_Human1.35241266
46EZH2_27294783_Chip-Seq_NPCs_Mouse1.35016157
47STAT4_19710469_ChIP-ChIP_TH1__Mouse1.34524451
48EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.30926566
49FOXA1_21572438_ChIP-Seq_LNCaP_Human1.30367527
50MYC_19030024_ChIP-ChIP_MESCs_Mouse1.27899607
51PCGF2_27294783_Chip-Seq_NPCs_Mouse1.25553204
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.24208525
53MYC_18940864_ChIP-ChIP_HL60_Human1.23727554
54SRY_22984422_ChIP-ChIP_TESTIS_Rat1.23279022
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.22146365
56SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.18665596
57EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.16295733
58P300_19829295_ChIP-Seq_ESCs_Human1.14627690
59STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.13083785
60MYB_26560356_Chip-Seq_TH2_Human1.11480733
61AUTS2_25519132_ChIP-Seq_293T-REX_Human1.11219905
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.10801293
63CRX_20693478_ChIP-Seq_RETINA_Mouse1.07863821
64NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.07655421
65TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.06282091
66PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05215399
67PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.04423516
68IRF8_21731497_ChIP-ChIP_J774_Mouse1.04239471
69FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.04171371
70SALL4_22934838_ChIP-ChIP_CD34+_Human1.02446228
71GATA3_26560356_Chip-Seq_TH1_Human1.02361077
72CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.00856998
73CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.00835250
74GATA3_26560356_Chip-Seq_TH2_Human1.00083471
75FUS_26573619_Chip-Seq_HEK293_Human0.98640649
76FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.97948784
77YY1_21170310_ChIP-Seq_MESCs_Mouse0.96954982
78TDRD3_21172665_ChIP-Seq_MCF-7_Human0.95009199
79CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.93712129
80HOXB7_26014856_ChIP-Seq_BT474_Human0.93662614
81SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.93236416
82ER_23166858_ChIP-Seq_MCF-7_Human0.92579731
83FOXH1_21741376_ChIP-Seq_EPCs_Human0.92545432
84MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92150019
85GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91447406
86GATA3_27048872_Chip-Seq_THYMUS_Human0.90996944
87TTF2_22483619_ChIP-Seq_HELA_Human0.90945773
88NCOR_22424771_ChIP-Seq_293T_Human0.90836455
89RBPJ_21746931_ChIP-Seq_IB4_Human0.90067582
90GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.89734536
91GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.89482690
92EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88466334
93BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.87693410
94RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.87635875
95CTBP2_25329375_ChIP-Seq_LNCAP_Human0.87552210
96OCT4_21477851_ChIP-Seq_ESCs_Mouse0.87374801
97POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87007983
98GATA6_21074721_ChIP-Seq_CACO-2_Human0.86236462
99SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.85394942
100CBP_20019798_ChIP-Seq_JUKART_Human0.84229171

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to4.46829568
2MP0003806_abnormal_nucleotide_metabolis4.11170136
3MP0006054_spinal_hemorrhage3.80333159
4MP0001835_abnormal_antigen_presentation3.45831647
5MP0000685_abnormal_immune_system3.34499913
6MP0001873_stomach_inflammation3.21628850
7MP0004145_abnormal_muscle_electrophysio3.04163040
8MP0009785_altered_susceptibility_to2.59232548
9MP0002166_altered_tumor_susceptibility2.55584704
10MP0003786_premature_aging2.42503087
11MP0002006_tumorigenesis2.26082027
12MP0004147_increased_porphyrin_level2.23009133
13MP0004381_abnormal_hair_follicle2.22721588
14MP0001853_heart_inflammation2.17926060
15MP0008995_early_reproductive_senescence2.10227877
16MP0008058_abnormal_DNA_repair2.09032104
17MP0002163_abnormal_gland_morphology2.07382980
18MP0006036_abnormal_mitochondrial_physio2.01132808
19MP0002876_abnormal_thyroid_physiology1.85992009
20MP0005408_hypopigmentation1.85518943
21MP0002148_abnormal_hypersensitivity_rea1.83287785
22MP0001800_abnormal_humoral_immune1.79813720
23MP0008875_abnormal_xenobiotic_pharmacok1.76143316
24MP0001501_abnormal_sleep_pattern1.75995228
25MP0006035_abnormal_mitochondrial_morpho1.75245086
26MP0003011_delayed_dark_adaptation1.73959069
27MP0002102_abnormal_ear_morphology1.70573512
28MP0001984_abnormal_olfaction1.64282112
29MP0006082_CNS_inflammation1.61843536
30MP0008872_abnormal_physiological_respon1.61012682
31MP0009764_decreased_sensitivity_to1.60707542
32MP0005000_abnormal_immune_tolerance1.58063216
33MP0001790_abnormal_immune_system1.50488495
34MP0005387_immune_system_phenotype1.50488495
35MP0005310_abnormal_salivary_gland1.48785402
36MP0004142_abnormal_muscle_tone1.48192279
37MP0005645_abnormal_hypothalamus_physiol1.46703026
38MP0004885_abnormal_endolymph1.44392318
39MP0003186_abnormal_redox_activity1.44004930
40MP0001529_abnormal_vocalization1.40768609
41MP0001919_abnormal_reproductive_system1.40306749
42MP0005379_endocrine/exocrine_gland_phen1.29474094
43MP0002420_abnormal_adaptive_immunity1.29271101
44MP0002723_abnormal_immune_serum1.26289940
45MP0005551_abnormal_eye_electrophysiolog1.25060352
46MP0001819_abnormal_immune_cell1.23615572
47MP0003436_decreased_susceptibility_to1.20504933
48MP0002751_abnormal_autonomic_nervous1.19714143
49MP0005389_reproductive_system_phenotype1.18219830
50MP0002452_abnormal_antigen_presenting1.17157794
51MP0002837_dystrophic_cardiac_calcinosis1.16282641
52MP0002693_abnormal_pancreas_physiology1.15084083
53MP0002234_abnormal_pharynx_morphology1.13388277
54MP0005330_cardiomyopathy1.11425549
55MP0002398_abnormal_bone_marrow1.09692330
56MP0005025_abnormal_response_to1.09060641
57MP0000372_irregular_coat_pigmentation1.07080430
58MP0000716_abnormal_immune_system1.04346562
59MP0002132_abnormal_respiratory_system1.04118741
60MP0005075_abnormal_melanosome_morpholog1.02919813
61MP0001348_abnormal_lacrimal_gland1.01788416
62MP0005167_abnormal_blood-brain_barrier1.01566184
63MP0003646_muscle_fatigue1.01293034
64MP0001502_abnormal_circadian_rhythm0.95315468
65MP0003567_abnormal_fetal_cardiomyocyte0.93853037
66MP0005646_abnormal_pituitary_gland0.93264791
67MP0003137_abnormal_impulse_conducting0.92911606
68MP0010094_abnormal_chromosome_stability0.88033868
69MP0002429_abnormal_blood_cell0.86499156
70MP0001727_abnormal_embryo_implantation0.86039908
71MP0002277_abnormal_respiratory_mucosa0.84440151
72MP0001845_abnormal_inflammatory_respons0.83041332
73MP0009745_abnormal_behavioral_response0.81504946
74MP0009379_abnormal_foot_pigmentation0.81348307
75MP0001293_anophthalmia0.81315400
76MP0000703_abnormal_thymus_morphology0.80136702
77MP0003111_abnormal_nucleus_morphology0.78441967
78MP0003195_calcinosis0.78186984
79MP0001944_abnormal_pancreas_morphology0.76644822
80MP0001486_abnormal_startle_reflex0.76113558
81MP0002090_abnormal_vision0.75768973
82MP0003763_abnormal_thymus_physiology0.74101629
83MP0000689_abnormal_spleen_morphology0.72181450
84MP0002127_abnormal_cardiovascular_syste0.70743584
85MP0002160_abnormal_reproductive_system0.70198984
86MP0005165_increased_susceptibility_to0.69795001
87MP0005535_abnormal_body_temperature0.69580683
88MP0008873_increased_physiological_sensi0.67543986
89MP0008469_abnormal_protein_level0.67516378
90MP0006072_abnormal_retinal_apoptosis0.67137328
91MP0005253_abnormal_eye_physiology0.66236079
92MP0005266_abnormal_metabolism0.64736210
93MP0001905_abnormal_dopamine_level0.63633999
94MP0004742_abnormal_vestibular_system0.63442226
95MP0002722_abnormal_immune_system0.62840091
96MP0005448_abnormal_energy_balance0.60056006
97MP0002419_abnormal_innate_immunity0.59385581
98MP0003448_altered_tumor_morphology0.58408483
99MP0000516_abnormal_urinary_system0.58146273
100MP0005367_renal/urinary_system_phenotyp0.58146273

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.06933272
2Lipid accumulation in hepatocytes (HP:0006561)4.66099603
3Increased hepatocellular lipid droplets (HP:0006565)4.63391527
4Acute encephalopathy (HP:0006846)4.54642311
5Mitochondrial inheritance (HP:0001427)4.53391865
6Elevated erythrocyte sedimentation rate (HP:0003565)4.48673032
7Progressive macrocephaly (HP:0004481)4.44795344
8Hepatocellular necrosis (HP:0001404)4.43533137
9Abnormal mitochondria in muscle tissue (HP:0008316)4.42108705
10Increased CSF lactate (HP:0002490)3.92922028
11Pigmentary retinal degeneration (HP:0001146)3.91730896
12Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.85231075
13Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.77415298
14Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.74530061
15Increased intramyocellular lipid droplets (HP:0012240)3.68743620
16Renal Fanconi syndrome (HP:0001994)3.55743572
17Hepatic necrosis (HP:0002605)3.52132027
18Increased muscle lipid content (HP:0009058)3.31854486
19Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.25652016
20Decreased activity of mitochondrial respiratory chain (HP:0008972)3.25652016
21Aplasia/hypoplasia of the uterus (HP:0008684)3.14378791
22Hypoproteinemia (HP:0003075)3.10303985
23Increased serum lactate (HP:0002151)3.07051365
24Hypoplasia of the uterus (HP:0000013)3.06749905
25Exertional dyspnea (HP:0002875)3.04661486
26Septate vagina (HP:0001153)2.96264582
27Sensory axonal neuropathy (HP:0003390)2.83219100
28Cerebral edema (HP:0002181)2.79506846
29Progressive inability to walk (HP:0002505)2.79300597
30Optic disc pallor (HP:0000543)2.66324556
31Congenital, generalized hypertrichosis (HP:0004540)2.65729904
32T lymphocytopenia (HP:0005403)2.64795288
33Leukodystrophy (HP:0002415)2.64329366
34Abnormality of aromatic amino acid family metabolism (HP:0004338)2.57705341
35Respiratory failure (HP:0002878)2.47721435
36Dyschromatopsia (HP:0007641)2.46149145
37Exercise intolerance (HP:0003546)2.42624246
38Abnormality of T cell number (HP:0011839)2.39788299
39Gangrene (HP:0100758)2.36599176
40Aplastic anemia (HP:0001915)2.35953635
41IgG deficiency (HP:0004315)2.35873033
42Supernumerary spleens (HP:0009799)2.26879712
43Abnormality of the prostate (HP:0008775)2.23537375
44Pancreatic cysts (HP:0001737)2.22541935
45Congenital ichthyosiform erythroderma (HP:0007431)2.18045434
46Hemoptysis (HP:0002105)2.10778535
47Abnormality of renal resorption (HP:0011038)2.10433657
48Prolonged neonatal jaundice (HP:0006579)2.08097510
49Respiratory difficulties (HP:0002880)2.05776360
50Hemiparesis (HP:0001269)2.04965822
51Hypothermia (HP:0002045)2.03727684
52Lower limb hyperreflexia (HP:0002395)2.03476487
53Petechiae (HP:0000967)2.00616784
54Abnormality of the pleura (HP:0002103)1.99864280
55Constricted visual fields (HP:0001133)1.99647467
56Congenital stationary night blindness (HP:0007642)1.99025464
57Aplasia/Hypoplasia of the uvula (HP:0010293)1.97649290
58Metaphyseal dysplasia (HP:0100255)1.94371876
59Lactic acidosis (HP:0003128)1.93740216
60Thyroiditis (HP:0100646)1.93473729
61Amniotic constriction ring (HP:0009775)1.93239023
62Abnormality of placental membranes (HP:0011409)1.93239023
63Abnormality of incisor morphology (HP:0011063)1.92453248
64Colon cancer (HP:0003003)1.91386077
65Abnormality of the anterior horn cell (HP:0006802)1.91218978
66Degeneration of anterior horn cells (HP:0002398)1.91218978
67Oral leukoplakia (HP:0002745)1.90625294
68Retrobulbar optic neuritis (HP:0100654)1.90226722
69Optic neuritis (HP:0100653)1.90226722
70Meckel diverticulum (HP:0002245)1.86250188
71Vasculitis (HP:0002633)1.86083207
72Conical tooth (HP:0000698)1.85259687
73Abnormality of the ileum (HP:0001549)1.84916121
74Paralysis (HP:0003470)1.84304058
75Pendular nystagmus (HP:0012043)1.83828417
76Palpitations (HP:0001962)1.81875422
77Chest pain (HP:0100749)1.81660603
78Increased IgM level (HP:0003496)1.81523179
79Hepatosplenomegaly (HP:0001433)1.81235989
80Ureteral stenosis (HP:0000071)1.80158081
81Abnormality of urine glucose concentration (HP:0011016)1.78589856
82Glycosuria (HP:0003076)1.78589856
83Poor head control (HP:0002421)1.78556995
84Cleft eyelid (HP:0000625)1.78308061
85Hypokalemic alkalosis (HP:0001949)1.78090647
86Abnormality of the preputium (HP:0100587)1.77753574
87Facial diplegia (HP:0001349)1.77378926
88Abnormality of the phalanges of the 2nd finger (HP:0009541)1.77344281
89Severe combined immunodeficiency (HP:0004430)1.77071097
90Pulmonary infiltrates (HP:0002113)1.75977234
91Chronic diarrhea (HP:0002028)1.75457320
92Absent thumb (HP:0009777)1.75300013
93Decreased electroretinogram (ERG) amplitude (HP:0000654)1.75134889
94Aplasia/Hypoplasia of the sacrum (HP:0008517)1.74350230
95Clubbing of toes (HP:0100760)1.72731730
96Basal ganglia calcification (HP:0002135)1.71943150
97Alveolar cell carcinoma (HP:0006519)1.71404562
98Abnormality of the renal cortex (HP:0011035)1.71352141
99Carpal bone hypoplasia (HP:0001498)1.68990860
100Retinopathy (HP:0000488)1.68639353

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK5.93278871
2VRK23.48097586
3MST43.45826921
4NUAK13.37891289
5MAP2K62.92610852
6FRK2.75040479
7TAOK32.56701652
8MAP3K122.47016150
9SRPK12.37407604
10MAP4K12.21207866
11TRIM282.04935397
12EIF2AK11.93587652
13TAF11.90954977
14MYLK1.80416227
15EIF2AK31.79111269
16WNK41.75543641
17ADRBK21.74804270
18DAPK11.66337444
19MAPKAPK31.57818053
20BMPR21.54397935
21STK38L1.52152631
22BMPR1B1.50240147
23STK391.48778661
24TLK11.47353746
25OXSR11.47299344
26VRK11.46103235
27BUB11.44836636
28TSSK61.43257986
29ZAK1.42480680
30EIF2AK21.33322516
31WNK31.27345972
32GRK71.17223248
33PLK31.10018867
34IKBKB1.07607590
35TYK21.03586698
36GRK11.01500936
37NME11.00021393
38TIE10.98562051
39ILK0.96767329
40PAK40.90478774
41MAPKAPK50.85541992
42KIT0.83131322
43KDR0.82582704
44CSF1R0.79019451
45CDC70.78531706
46DAPK30.77947307
47SMG10.77329542
48MAP4K20.77093343
49OBSCN0.76307164
50SYK0.64280415
51TRPM70.64101786
52CDK190.62092033
53PLK20.61051580
54PHKG10.60654217
55PHKG20.60654217
56PRKCI0.60372509
57MUSK0.59402896
58CDK80.57490403
59ATR0.56240358
60INSRR0.55329571
61MAPK130.54006249
62NEK60.52582231
63AKT30.51664337
64PRKAA20.50860813
65TEC0.49379776
66CAMK2D0.49228064
67PINK10.48574912
68CSNK1G10.47870377
69MARK30.47668801
70IKBKE0.47325707
71DYRK1A0.47143608
72PAK10.47011990
73LCK0.46541896
74LYN0.46400372
75PRKCG0.46298415
76PRKCE0.45625048
77GRK50.44935193
78PASK0.44693092
79PAK30.44305072
80CSNK1G30.44259206
81RIPK40.41259954
82PRKCQ0.40295718
83PIK3CA0.39333998
84DYRK30.38747147
85STK110.38569069
86STK240.37204462
87IGF1R0.36991508
88CSNK2A20.36391911
89MAP3K140.36235266
90PRKCD0.35572467
91ITK0.33992677
92PRKG10.33636273
93CAMK2B0.32647125
94WEE10.31566894
95PLK10.31425338
96PRKCA0.31417804
97CAMK2A0.30861806
98NEK10.30708572
99PRKACA0.30491585
100CAMK2G0.30378457

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.06930860
2Oxidative phosphorylation_Homo sapiens_hsa001903.48092413
3Protein export_Homo sapiens_hsa030603.40381849
4Asthma_Homo sapiens_hsa053103.20305681
5Type I diabetes mellitus_Homo sapiens_hsa049402.96816490
6Autoimmune thyroid disease_Homo sapiens_hsa053202.95952688
7Parkinsons disease_Homo sapiens_hsa050122.78267370
8Allograft rejection_Homo sapiens_hsa053302.62958511
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.52062360
10Primary immunodeficiency_Homo sapiens_hsa053402.34375166
11One carbon pool by folate_Homo sapiens_hsa006702.32948131
12Ribosome_Homo sapiens_hsa030102.30798146
13RNA polymerase_Homo sapiens_hsa030202.24857736
14Graft-versus-host disease_Homo sapiens_hsa053322.15220554
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12894971
16Non-homologous end-joining_Homo sapiens_hsa034502.04319173
17Antigen processing and presentation_Homo sapiens_hsa046122.01338927
18Huntingtons disease_Homo sapiens_hsa050161.96070493
19Alzheimers disease_Homo sapiens_hsa050101.92687325
20Cardiac muscle contraction_Homo sapiens_hsa042601.81775283
21Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.68402258
22Hematopoietic cell lineage_Homo sapiens_hsa046401.64841961
23RNA degradation_Homo sapiens_hsa030181.56920808
24Folate biosynthesis_Homo sapiens_hsa007901.49801442
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.47728450
26Rheumatoid arthritis_Homo sapiens_hsa053231.44669853
27Homologous recombination_Homo sapiens_hsa034401.43998222
28Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.43427840
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.41518029
30Spliceosome_Homo sapiens_hsa030401.22835453
31Nucleotide excision repair_Homo sapiens_hsa034201.22404917
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.19298001
33Linoleic acid metabolism_Homo sapiens_hsa005911.18130238
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.17884793
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.17628069
36DNA replication_Homo sapiens_hsa030301.09101184
37NF-kappa B signaling pathway_Homo sapiens_hsa040641.05765148
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.03977068
39Phototransduction_Homo sapiens_hsa047441.03931619
40Nitrogen metabolism_Homo sapiens_hsa009101.02390044
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.00194754
42Mismatch repair_Homo sapiens_hsa034300.94899763
43Fanconi anemia pathway_Homo sapiens_hsa034600.92014406
44Pyrimidine metabolism_Homo sapiens_hsa002400.87297723
45Purine metabolism_Homo sapiens_hsa002300.84539017
46Tryptophan metabolism_Homo sapiens_hsa003800.83065247
47Viral myocarditis_Homo sapiens_hsa054160.79804989
48Basal transcription factors_Homo sapiens_hsa030220.75579892
49Maturity onset diabetes of the young_Homo sapiens_hsa049500.74936375
50Ether lipid metabolism_Homo sapiens_hsa005650.71832435
51Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68915269
52Butanoate metabolism_Homo sapiens_hsa006500.68478083
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.67342002
54Leishmaniasis_Homo sapiens_hsa051400.65121197
55Collecting duct acid secretion_Homo sapiens_hsa049660.64085693
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.63485542
57Caffeine metabolism_Homo sapiens_hsa002320.63475783
58Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61287624
59Systemic lupus erythematosus_Homo sapiens_hsa053220.60225618
60Staphylococcus aureus infection_Homo sapiens_hsa051500.59984052
61Chemical carcinogenesis_Homo sapiens_hsa052040.58127597
62Epstein-Barr virus infection_Homo sapiens_hsa051690.56138525
63T cell receptor signaling pathway_Homo sapiens_hsa046600.55998418
64Herpes simplex infection_Homo sapiens_hsa051680.54557089
65Propanoate metabolism_Homo sapiens_hsa006400.52432106
66Cysteine and methionine metabolism_Homo sapiens_hsa002700.52191860
67RNA transport_Homo sapiens_hsa030130.49864160
68Base excision repair_Homo sapiens_hsa034100.48843725
69Olfactory transduction_Homo sapiens_hsa047400.45260215
70Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43462005
71Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38567419
72mRNA surveillance pathway_Homo sapiens_hsa030150.38285133
73Metabolic pathways_Homo sapiens_hsa011000.36014756
74Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.34992909
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.32923006
76Vitamin digestion and absorption_Homo sapiens_hsa049770.32681591
77Regulation of autophagy_Homo sapiens_hsa041400.31801468
78Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30051176
79Pyruvate metabolism_Homo sapiens_hsa006200.29795414
80Measles_Homo sapiens_hsa051620.29781189
81Retinol metabolism_Homo sapiens_hsa008300.28689366
82Arachidonic acid metabolism_Homo sapiens_hsa005900.28254026
83Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.28075434
84NOD-like receptor signaling pathway_Homo sapiens_hsa046210.27649914
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.27500464
86Selenocompound metabolism_Homo sapiens_hsa004500.26130836
87Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.25083295
88Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.23859668
89Circadian rhythm_Homo sapiens_hsa047100.22483434
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.22340492
91Mineral absorption_Homo sapiens_hsa049780.22084819
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.21847926
93Toll-like receptor signaling pathway_Homo sapiens_hsa046200.21264418
94Legionellosis_Homo sapiens_hsa051340.21088599
95Fatty acid degradation_Homo sapiens_hsa000710.20202564
96Nicotine addiction_Homo sapiens_hsa050330.19989704
97Drug metabolism - other enzymes_Homo sapiens_hsa009830.18990756
98Renin-angiotensin system_Homo sapiens_hsa046140.15873626
99Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.14997684
100Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.14364376

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »