SNTN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1CTP biosynthetic process (GO:0006241)9.90805407
2CTP metabolic process (GO:0046036)9.90805407
3guanosine-containing compound biosynthetic process (GO:1901070)9.75654691
4ventricular system development (GO:0021591)9.18600139
5pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)9.17054478
6pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)8.72245275
7left/right axis specification (GO:0070986)8.58853331
8primary alcohol catabolic process (GO:0034310)7.65509381
9pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)7.47627896
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.46646035
11vitamin transmembrane transport (GO:0035461)6.85051238
12pyrimidine nucleoside triphosphate metabolic process (GO:0009147)6.69759796
13diterpenoid biosynthetic process (GO:0016102)6.35792450
14nucleotide phosphorylation (GO:0046939)6.34337143
15ethanol metabolic process (GO:0006067)6.32898009
16pyrimidine ribonucleoside biosynthetic process (GO:0046132)6.04250602
17microtubule bundle formation (GO:0001578)6.00828783
18pyrimidine ribonucleotide biosynthetic process (GO:0009220)5.78105980
19nucleoside diphosphate metabolic process (GO:0009132)5.57346910
20pyrimidine-containing compound transmembrane transport (GO:0072531)5.47962726
21response to xenobiotic stimulus (GO:0009410)5.43921142
22tolerance induction (GO:0002507)5.28376310
23pyrimidine ribonucleotide metabolic process (GO:0009218)5.28056959
24intraciliary transport (GO:0042073)5.18002809
25regulation of glucose import in response to insulin stimulus (GO:2001273)5.05569944
26centriole assembly (GO:0098534)5.04093931
27protein localization to cilium (GO:0061512)5.01164437
28regulation of macrophage chemotaxis (GO:0010758)4.99493731
29cilium organization (GO:0044782)4.96835631
30regulation of microtubule-based movement (GO:0060632)4.90324727
31one-carbon compound transport (GO:0019755)4.89355035
32motile cilium assembly (GO:0044458)4.88783491
33ethanol oxidation (GO:0006069)4.84736051
34lung epithelium development (GO:0060428)4.75301920
35pyrimidine ribonucleoside metabolic process (GO:0046131)4.66628818
36negative regulation of T cell differentiation in thymus (GO:0033085)4.65056750
37terpenoid biosynthetic process (GO:0016114)4.60108140
38regulation of interleukin-5 production (GO:0032674)4.54039427
39cilium assembly (GO:0042384)4.44802994
40regulation of mononuclear cell migration (GO:0071675)4.42856857
41pyrimidine nucleotide biosynthetic process (GO:0006221)4.39251799
42sperm capacitation (GO:0048240)4.38637403
43retinoic acid metabolic process (GO:0042573)4.38109567
44establishment of apical/basal cell polarity (GO:0035089)4.35581584
45purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.32893624
46regulation of germinal center formation (GO:0002634)4.29966454
47negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.29024357
48purine nucleoside triphosphate biosynthetic process (GO:0009145)4.22269753
49pyrimidine nucleoside biosynthetic process (GO:0046134)4.10233904
50regulation of interleukin-13 production (GO:0032656)4.05291481
51cellular component assembly involved in morphogenesis (GO:0010927)3.96656955
52microtubule-based movement (GO:0007018)3.95526874
53establishment or maintenance of monopolar cell polarity (GO:0061339)3.84092850
54establishment of monopolar cell polarity (GO:0061162)3.84092850
55exogenous drug catabolic process (GO:0042738)3.82257900
56axon ensheathment in central nervous system (GO:0032291)3.82108340
57central nervous system myelination (GO:0022010)3.82108340
58cytoplasmic microtubule organization (GO:0031122)3.77820150
59positive regulation of cellular response to insulin stimulus (GO:1900078)3.77147417
60ribonucleoside triphosphate biosynthetic process (GO:0009201)3.74936178
61brain morphogenesis (GO:0048854)3.73385887
62multicellular organismal aging (GO:0010259)3.71190470
63cilium morphogenesis (GO:0060271)3.65669844
64nucleoside triphosphate biosynthetic process (GO:0009142)3.55003773
65microtubule depolymerization (GO:0007019)3.51400074
66retinol metabolic process (GO:0042572)3.44829261
67primary alcohol metabolic process (GO:0034308)3.44652269
68cell projection assembly (GO:0030031)3.44191684
69microtubule polymerization or depolymerization (GO:0031109)3.33212553
70glutathione derivative metabolic process (GO:1901685)3.32864991
71glutathione derivative biosynthetic process (GO:1901687)3.32864991
72pyrimidine-containing compound biosynthetic process (GO:0072528)3.32763683
73O-glycan processing (GO:0016266)3.29003110
74establishment of planar polarity (GO:0001736)3.24794984
75establishment of tissue polarity (GO:0007164)3.24794984
76hydrogen peroxide biosynthetic process (GO:0050665)3.09854080
77pyrimidine nucleotide metabolic process (GO:0006220)3.05987405
78oxygen transport (GO:0015671)3.05854398
79aldehyde catabolic process (GO:0046185)3.05352825
80positive regulation of meiosis (GO:0045836)3.03743908
81drug catabolic process (GO:0042737)3.03641452
82epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.02878471
83embryonic digestive tract development (GO:0048566)3.02807652
84otic vesicle formation (GO:0030916)3.00451873
85positive regulation of smoothened signaling pathway (GO:0045880)2.99082924
86regulation of tolerance induction (GO:0002643)2.98483957
87regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.97700516
88sperm motility (GO:0030317)2.95775333
89retinal rod cell development (GO:0046548)2.95437346
90gas transport (GO:0015669)2.91229313
91centriole replication (GO:0007099)2.84441771
92lateral sprouting from an epithelium (GO:0060601)2.84436602
93smoothened signaling pathway (GO:0007224)2.83729482
94positive regulation of meiotic cell cycle (GO:0051446)2.77353533
95microtubule-based process (GO:0007017)2.77091262
96reactive oxygen species biosynthetic process (GO:1903409)2.75799178
97progesterone metabolic process (GO:0042448)2.74258199
98phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.74002281
99negative regulation of humoral immune response (GO:0002921)2.73221986
100regulation of microtubule depolymerization (GO:0031114)2.72936532
101multicellular organismal water homeostasis (GO:0050891)2.72354743
102pyrimidine nucleoside metabolic process (GO:0006213)2.69569659
103cornea development in camera-type eye (GO:0061303)2.69247846
104carnitine metabolic process (GO:0009437)2.68894038
105lateral ventricle development (GO:0021670)2.62909928
106calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.61938245
107cellular response to nicotine (GO:0071316)2.60501643
108excretion (GO:0007588)2.60441874
109organelle assembly (GO:0070925)2.60277547
110apical protein localization (GO:0045176)2.58355963
111phosphatidylcholine biosynthetic process (GO:0006656)2.57863802
112ADP metabolic process (GO:0046031)2.56169824
113regulation of autophagic vacuole assembly (GO:2000785)2.55342311
114regulation of mesenchymal cell apoptotic process (GO:2001053)2.54685366
115regulation of cilium movement (GO:0003352)2.51782931
116hydrogen peroxide catabolic process (GO:0042744)2.51202095
117photoreceptor cell maintenance (GO:0045494)2.48437928
118oligosaccharide biosynthetic process (GO:0009312)2.45293387
119regulation of pigment cell differentiation (GO:0050932)2.44205979
120dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.43754332
121deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.40683759
122protein O-linked glycosylation (GO:0006493)2.38635285
123iron ion import (GO:0097286)2.38590341
124photoreceptor cell differentiation (GO:0046530)2.38324928
125eye photoreceptor cell differentiation (GO:0001754)2.38324928
126retinal cone cell development (GO:0046549)2.37205423
127sodium ion homeostasis (GO:0055078)2.36957946
128heart looping (GO:0001947)2.35461613
129heart valve formation (GO:0003188)2.34679428
130water homeostasis (GO:0030104)2.34295202
131glomerular epithelial cell development (GO:0072310)2.32986316
132limb bud formation (GO:0060174)2.28765944
133endocardial cushion morphogenesis (GO:0003203)2.27849772
134positive regulation of extracellular matrix organization (GO:1903055)2.26882649
135cerebral cortex neuron differentiation (GO:0021895)2.24128702
136negative regulation of inclusion body assembly (GO:0090084)2.22931611
137regulation of male gonad development (GO:2000018)2.21764765
138left/right pattern formation (GO:0060972)2.20688006
139determination of left/right symmetry (GO:0007368)2.20613772
140negative regulation of astrocyte differentiation (GO:0048712)2.15946323
141embryonic camera-type eye development (GO:0031076)2.15652928
142determination of bilateral symmetry (GO:0009855)2.12602887
143negative regulation of B cell mediated immunity (GO:0002713)2.11221795
144negative regulation of immunoglobulin mediated immune response (GO:0002890)2.11221795
145microtubule severing (GO:0051013)2.09064244
146specification of symmetry (GO:0009799)2.08978550
147establishment of protein localization to mitochondrial membrane (GO:0090151)2.08433995
148regulation of granulocyte chemotaxis (GO:0071622)2.08325372
149developmental induction (GO:0031128)2.06891913
150regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.05187508
151cell-cell signaling involved in cell fate commitment (GO:0045168)2.02244913
152cilium movement (GO:0003341)15.3577860
153GTP biosynthetic process (GO:0006183)14.4892213
154axoneme assembly (GO:0035082)13.7329381
155UTP biosynthetic process (GO:0006228)13.0670571
156UTP metabolic process (GO:0046051)12.1448916
157axonemal dynein complex assembly (GO:0070286)11.5836530
158nucleoside diphosphate phosphorylation (GO:0006165)11.4369305
159cilium or flagellum-dependent cell motility (GO:0001539)10.5558187
160epithelial cilium movement (GO:0003351)10.4695579
161polyketide metabolic process (GO:0030638)1.99050702
162doxorubicin metabolic process (GO:0044598)1.99050702
163daunorubicin metabolic process (GO:0044597)1.99050702
164cysteine metabolic process (GO:0006534)1.98292350
165protein palmitoylation (GO:0018345)1.96141117
166positive regulation of tolerance induction (GO:0002645)1.94849312
167hair follicle development (GO:0001942)1.94567687
168nonmotile primary cilium assembly (GO:0035058)1.94055948
169regulation of hippo signaling (GO:0035330)1.93269055

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.56264630
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.79428701
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.69079163
4FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.58530755
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.44180798
6CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.08924221
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.01005009
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.68055029
9AR_21572438_ChIP-Seq_LNCaP_Human2.63728967
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.48793692
11VDR_22108803_ChIP-Seq_LS180_Human2.38270176
12ESR1_20079471_ChIP-ChIP_T-47D_Human2.36075276
13AHR_22903824_ChIP-Seq_MCF-7_Human2.17519686
14CDX2_19796622_ChIP-Seq_MESCs_Mouse2.07335125
15TRIM28_21343339_ChIP-Seq_HEK293_Human2.04430967
16FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.90087806
17PIAS1_25552417_ChIP-Seq_VCAP_Human1.85225685
18STAT1_20625510_ChIP-Seq_HELA_Human1.83070730
19* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.82083071
20ESR1_21235772_ChIP-Seq_MCF-7_Human1.81002781
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.76728396
22SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.75337816
23P300_19829295_ChIP-Seq_ESCs_Human1.73210113
24JARID2_20075857_ChIP-Seq_MESCs_Mouse1.72206736
25SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.70899515
26* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.70692268
27AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.70140075
28GATA1_26923725_Chip-Seq_HPCs_Mouse1.68253241
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68212815
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.67519487
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.66545580
32SOX2_27498859_Chip-Seq_STOMACH_Mouse1.66342295
33SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.65751539
34* TP63_23658742_ChIP-Seq_EP156T_Human1.65738207
35JARID2_20064375_ChIP-Seq_MESCs_Mouse1.65367697
36SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.64899264
37EZH2_27294783_Chip-Seq_ESCs_Mouse1.63381826
38DROSHA_22980978_ChIP-Seq_HELA_Human1.62756039
39EED_16625203_ChIP-ChIP_MESCs_Mouse1.59885146
40SUZ12_27294783_Chip-Seq_ESCs_Mouse1.59446553
41SMAD4_21799915_ChIP-Seq_A2780_Human1.59150659
42ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.57414712
43RNF2_18974828_ChIP-Seq_MESCs_Mouse1.56378588
44EZH2_18974828_ChIP-Seq_MESCs_Mouse1.56378588
45* RUNX1_27514584_Chip-Seq_MCF-7_Human1.56094534
46CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.54572234
47SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.54020266
48PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.52215086
49EZH2_27304074_Chip-Seq_ESCs_Mouse1.52087328
50WT1_19549856_ChIP-ChIP_CCG9911_Human1.52007006
51ESR2_21235772_ChIP-Seq_MCF-7_Human1.51639349
52BCAT_22108803_ChIP-Seq_LS180_Human1.51502078
53SMC4_20622854_ChIP-Seq_HELA_Human1.50629152
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.50409105
55MTF2_20144788_ChIP-Seq_MESCs_Mouse1.48131279
56EZH2_22144423_ChIP-Seq_EOC_Human1.48115961
57FOXA1_25552417_ChIP-Seq_VCAP_Human1.47837851
58STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.47352669
59P53_22127205_ChIP-Seq_FIBROBLAST_Human1.45684496
60SUZ12_27294783_Chip-Seq_NPCs_Mouse1.45529965
61SMRT_27268052_Chip-Seq_Bcells_Human1.44728606
62CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.43412757
63* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43125926
64TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42178695
65PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.41931425
66RNF2_27304074_Chip-Seq_NSC_Mouse1.41905610
67TAF15_26573619_Chip-Seq_HEK293_Human1.41591173
68SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.41529103
69PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.41199943
70GBX2_23144817_ChIP-Seq_PC3_Human1.41044048
71NR3C1_21868756_ChIP-Seq_MCF10A_Human1.40770077
72* ETV1_20927104_ChIP-Seq_GIST48_Human1.40668175
73LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39530912
74KLF5_25053715_ChIP-Seq_YYC3_Human1.39134824
75P63_26484246_Chip-Seq_KERATINOCYTES_Human1.38348985
76PHF8_20622853_ChIP-Seq_HELA_Human1.37138450
77BMI1_23680149_ChIP-Seq_NPCS_Mouse1.37012294
78TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.36968221
79SOX2_20726797_ChIP-Seq_SW620_Human1.36845810
80CTNNB1_20460455_ChIP-Seq_HCT116_Human1.35837371
81RAD21_21589869_ChIP-Seq_MESCs_Mouse1.35673293
82CBX2_27304074_Chip-Seq_ESCs_Mouse1.33959689
83CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.32749404
84HNFA_21074721_ChIP-Seq_CACO-2_Human1.32243717
85* ER_23166858_ChIP-Seq_MCF-7_Human1.31822751
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.31458670
87SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31451794
88ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.31409518
89TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30063857
90POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.30063857
91TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29540640
92* TP63_22573176_ChIP-Seq_HFKS_Human1.29493201
93CDX2_20551321_ChIP-Seq_CACO-2_Human1.25935234
94RBPJ_21746931_ChIP-Seq_IB4_Human1.24915266
95PCGF2_27294783_Chip-Seq_NPCs_Mouse1.24876112
96SMAD3_21741376_ChIP-Seq_EPCs_Human1.22922433
97SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.21876897
98ARNT_22903824_ChIP-Seq_MCF-7_Human1.21719544
99* TDRD3_21172665_ChIP-Seq_MCF-7_Human1.21371405
100SOX9_24532713_ChIP-Seq_HFSC_Mouse1.20914503
101GATA4_25053715_ChIP-Seq_YYC3_Human1.20905604
102ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20845371
103SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20420271
104FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.18820209
105GATA1_19941826_ChIP-Seq_K562_Human1.17161593
106CBX2_22325352_ChIP-Seq_293T-Rex_Human1.15927889
107GATA6_21074721_ChIP-Seq_CACO-2_Human1.15048187
108ELF1_20517297_ChIP-Seq_JURKAT_Human1.14830689
109PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14164120
110* SMAD4_21741376_ChIP-Seq_EPCs_Human1.13495946
111RNF2_27304074_Chip-Seq_ESCs_Mouse1.13399501
112TP53_18474530_ChIP-ChIP_U2OS_Human1.13070769
113NFE2_27457419_Chip-Seq_LIVER_Mouse1.12963330
114CEBPB_22108803_ChIP-Seq_LS180_Human1.12459823
115GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.12372029
116NFYA_21822215_ChIP-Seq_K562_Human1.12104101
117EWS_26573619_Chip-Seq_HEK293_Human1.11946318
118FOXO3_23340844_ChIP-Seq_DLD1_Human1.11873281
119SMAD3_21741376_ChIP-Seq_HESCs_Human1.11756630
120PRDM14_20953172_ChIP-Seq_ESCs_Human1.11431089
121PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11116723
122FLI1_27457419_Chip-Seq_LIVER_Mouse1.10311212
123FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.10008561
124TP53_20018659_ChIP-ChIP_R1E_Mouse1.09885112
125RXR_22108803_ChIP-Seq_LS180_Human1.09846450
126CJUN_26792858_Chip-Seq_BT549_Human1.09786230
127GATA3_24758297_ChIP-Seq_MCF-7_Human1.09196389
128ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.09191684
129TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.08741793
130EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.08692344
131AUTS2_25519132_ChIP-Seq_293T-REX_Human1.08394496
132RING1B_27294783_Chip-Seq_ESCs_Mouse1.07369212
133LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05623885
134CTCF_20526341_ChIP-Seq_ESCs_Human1.04914671
135YY1_22570637_ChIP-Seq_MALME-3M_Human1.04232197
136EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.04035938
137FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.04019659
138NFYB_21822215_ChIP-Seq_K562_Human1.03773993
139ZFX_18555785_Chip-Seq_ESCs_Mouse1.03226505
140SMAD4_21741376_ChIP-Seq_HESCs_Human1.03055331
141SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02748161
142TBL1_22424771_ChIP-Seq_293T_Human1.02500793
143BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.01837678
144POU3F2_20337985_ChIP-ChIP_501MEL_Human1.01559512
145LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01469650
146STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.01205961
147ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01105896
148PPAR_26484153_Chip-Seq_NCI-H1993_Human0.99979285
149EP300_21415370_ChIP-Seq_HL-1_Mouse0.99920048
150FOXA2_19822575_ChIP-Seq_HepG2_Human0.99768417
151NANOG_18555785_Chip-Seq_ESCs_Mouse0.99255834
152MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.98913760
153CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98827712
154RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.98576741
155* FOXA1_25329375_ChIP-Seq_VCAP_Human0.98449583
156* FOXA1_27270436_Chip-Seq_PROSTATE_Human0.98449583
157KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.97643233
158EZH2_27294783_Chip-Seq_NPCs_Mouse0.97249724
159AR_25329375_ChIP-Seq_VCAP_Human0.96822976
160STAT3_18555785_Chip-Seq_ESCs_Mouse0.96670774
161WT1_25993318_ChIP-Seq_PODOCYTE_Human0.96632841
162P300_27268052_Chip-Seq_Bcells_Human0.96184358
163TP53_16413492_ChIP-PET_HCT116_Human0.96101085
164EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.95378250
165CRX_20693478_ChIP-Seq_RETINA_Mouse0.94979085
166STAT3_23295773_ChIP-Seq_U87_Human0.94957166
167SOX2_18555785_Chip-Seq_ESCs_Mouse0.94861929
168SMAD_19615063_ChIP-ChIP_OVARY_Human0.93584975
169PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.93423314
170SALL4_18804426_ChIP-ChIP_XEN_Mouse0.92064395
171CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.92007543
172GATA1_22025678_ChIP-Seq_K562_Human0.91993470
173CTCF_27219007_Chip-Seq_Bcells_Human0.91575094
174TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.91323522
175* AR_20517297_ChIP-Seq_VCAP_Human0.91165508
176RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.90941415
177CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.90099358
178PHF8_20622854_ChIP-Seq_HELA_Human0.89965963
179* TCF4_22108803_ChIP-Seq_LS180_Human0.89608216
180VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.86901402

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color6.64267551
2MP0005623_abnormal_meninges_morphology5.50961091
3MP0002653_abnormal_ependyma_morphology4.94019498
4MP0008004_abnormal_stomach_pH4.27631387
5MP0004043_abnormal_pH_regulation4.22305456
6MP0002277_abnormal_respiratory_mucosa3.94819824
7MP0005646_abnormal_pituitary_gland3.72154221
8MP0001440_abnormal_grooming_behavior2.62924636
9MP0000566_synostosis2.55251308
10MP0004133_heterotaxia2.50121627
11MP0000383_abnormal_hair_follicle2.46563896
12MP0004019_abnormal_vitamin_homeostasis2.24537177
13MP0002282_abnormal_trachea_morphology2.22382212
14MP0009046_muscle_twitch2.13888076
15MP0005377_hearing/vestibular/ear_phenot2.11305019
16MP0003878_abnormal_ear_physiology2.11305019
17MP0010678_abnormal_skin_adnexa2.11009256
18MP0003656_abnormal_erythrocyte_physiolo1.99722020
19MP0002249_abnormal_larynx_morphology1.99438801
20MP0004858_abnormal_nervous_system1.96279398
21MP0005083_abnormal_biliary_tract1.89893978
22MP0004381_abnormal_hair_follicle1.82763716
23MP0003690_abnormal_glial_cell1.78558842
24MP0002735_abnormal_chemical_nociception1.73373701
25MP0005167_abnormal_blood-brain_barrier1.69572961
26MP0001501_abnormal_sleep_pattern1.64444861
27MP0003937_abnormal_limbs/digits/tail_de1.57351639
28MP0000778_abnormal_nervous_system1.51480733
29MP0001346_abnormal_lacrimal_gland1.50767073
30MP0002133_abnormal_respiratory_system1.47658514
31MP0005388_respiratory_system_phenotype1.47658514
32MP0003938_abnormal_ear_development1.46756562
33MP0002909_abnormal_adrenal_gland1.46218847
34MP0009384_cardiac_valve_regurgitation1.42822932
35MP0000049_abnormal_middle_ear1.39533213
36MP0002168_other_aberrant_phenotype1.38715570
37MP0003303_peritoneal_inflammation1.36977474
38MP0001851_eye_inflammation1.36975148
39MP0002876_abnormal_thyroid_physiology1.36719698
40MP0004142_abnormal_muscle_tone1.35839482
41MP0005636_abnormal_mineral_homeostasis1.34153861
42MP0010155_abnormal_intestine_physiology1.33846522
43MP0001958_emphysema1.31619386
44MP0005165_increased_susceptibility_to1.30712446
45MP0003724_increased_susceptibility_to1.30224808
46MP0009250_abnormal_appendicular_skeleto1.28257016
47MP0000678_abnormal_parathyroid_gland1.27923480
48MP0000428_abnormal_craniofacial_morphol1.27341335
49MP0004782_abnormal_surfactant_physiolog1.27066201
50MP0009745_abnormal_behavioral_response1.26297972
51MP0002734_abnormal_mechanical_nocicepti1.25487232
52MP0002928_abnormal_bile_duct1.25111346
53MP0002557_abnormal_social/conspecific_i1.24243257
54MP0003634_abnormal_glial_cell1.23983943
55MP0002736_abnormal_nociception_after1.23673168
56MP0002572_abnormal_emotion/affect_behav1.23523486
57MP0001968_abnormal_touch/_nociception1.23125060
58MP0008875_abnormal_xenobiotic_pharmacok1.22665415
59MP0004859_abnormal_synaptic_plasticity1.21330845
60MP0003950_abnormal_plasma_membrane1.20852459
61MP0003880_abnormal_central_pattern1.18325938
62MP0005551_abnormal_eye_electrophysiolog1.17376528
63MP0002064_seizures1.14715519
64MP0001177_atelectasis1.14124535
65MP0005248_abnormal_Harderian_gland1.13429730
66MP0001663_abnormal_digestive_system1.13151154
67MP0005389_reproductive_system_phenotype1.10515914
68MP0000465_gastrointestinal_hemorrhage1.10008973
69MP0003635_abnormal_synaptic_transmissio1.07531337
70MP0001270_distended_abdomen1.06659944
71MP0010234_abnormal_vibrissa_follicle1.06413449
72MP0002254_reproductive_system_inflammat1.05711918
73MP0002132_abnormal_respiratory_system1.05341907
74MP0000631_abnormal_neuroendocrine_gland1.04463268
75MP0000470_abnormal_stomach_morphology1.02737743
76MP0005408_hypopigmentation1.00967327
77MP0005365_abnormal_bile_salt1.00245507
78MP0002160_abnormal_reproductive_system0.99521205
79MP0005381_digestive/alimentary_phenotyp0.97080628
80MP0009379_abnormal_foot_pigmentation0.97024094
81MP0002272_abnormal_nervous_system0.95545520
82MP0004145_abnormal_muscle_electrophysio0.92919419
83MP0005164_abnormal_response_to0.91094212
84MP0003122_maternal_imprinting0.91075811
85MP0009643_abnormal_urine_homeostasis0.90955538
86MP0005085_abnormal_gallbladder_physiolo0.89514854
87MP0005395_other_phenotype0.89427854
88MP0003075_altered_response_to0.89198128
89MP0004270_analgesia0.88892040
90MP0003186_abnormal_redox_activity0.88133051
91MP0001905_abnormal_dopamine_level0.85943121
92MP0002136_abnormal_kidney_physiology0.84834656
93MP0003633_abnormal_nervous_system0.83707879
94MP0001970_abnormal_pain_threshold0.83139206
95MP0000681_abnormal_thyroid_gland0.82531444
96MP0003385_abnormal_body_wall0.82096370
97MP0004883_abnormal_blood_vessel0.81992473
98MP0005220_abnormal_exocrine_pancreas0.81564631
99MP0006292_abnormal_olfactory_placode0.81545829
100MP0002233_abnormal_nose_morphology0.81406869
101MP0005647_abnormal_sex_gland0.80835923
102MP0000613_abnormal_salivary_gland0.80768674
103MP0002638_abnormal_pupillary_reflex0.79051519
104MP0001929_abnormal_gametogenesis0.78962958
105MP0005310_abnormal_salivary_gland0.78834659
106MP0005595_abnormal_vascular_smooth0.78599493
107MP0000750_abnormal_muscle_regeneration0.78545422
108MP0002063_abnormal_learning/memory/cond0.78072317
109MP0001486_abnormal_startle_reflex0.77870118
110MP0008789_abnormal_olfactory_epithelium0.76058775
111MP0002332_abnormal_exercise_endurance0.76017043
112MP0004264_abnormal_extraembryonic_tissu0.75499834
113MP0003698_abnormal_male_reproductive0.74178029
114MP0001984_abnormal_olfaction0.74032089
115MP0002896_abnormal_bone_mineralization0.73725229
116MP0009765_abnormal_xenobiotic_induced0.73397046
117MP0001664_abnormal_digestion0.73082829
118MP0002971_abnormal_brown_adipose0.72402368
119MP0001324_abnormal_eye_pigmentation0.72312305
120MP0002152_abnormal_brain_morphology0.72106196
121MP0008872_abnormal_physiological_respon0.70778078
122MP0005332_abnormal_amino_acid0.70276393
123MP0000026_abnormal_inner_ear0.69548448
124MP0002098_abnormal_vibrissa_morphology0.68830998
125MP0005503_abnormal_tendon_morphology0.66520097
126MP0002116_abnormal_craniofacial_bone0.66104006
127MP0003866_abnormal_defecation0.65678201
128MP0005499_abnormal_olfactory_system0.65591295
129MP0005394_taste/olfaction_phenotype0.65591295
130MP0009780_abnormal_chondrocyte_physiolo0.65223462
131MP0002938_white_spotting0.64763354
132MP0004272_abnormal_basement_membrane0.64572433
133MP0001727_abnormal_embryo_implantation0.64006411
134MP0002405_respiratory_system_inflammati0.63565372
135MP0001765_abnormal_ion_homeostasis0.62926824
136MP0001340_abnormal_eyelid_morphology0.62862866
137MP0002139_abnormal_hepatobiliary_system0.62245550
138MP0009763_increased_sensitivity_to0.61756770
139MP0001943_abnormal_respiration0.61473529
140MP0002882_abnormal_neuron_morphology0.60839251
141MP0005253_abnormal_eye_physiology0.60774555
142MP0001485_abnormal_pinna_reflex0.59701958
143MP0006082_CNS_inflammation0.59056883
144MP0010030_abnormal_orbit_morphology0.58944331
145MP0001944_abnormal_pancreas_morphology0.58816129
146MP0003806_abnormal_nucleotide_metabolis0.58095806
147MP0001790_abnormal_immune_system0.58082776
148MP0005387_immune_system_phenotype0.58082776
149MP0001293_anophthalmia0.57713607
150MP0005195_abnormal_posterior_eye0.54311297
151MP0001849_ear_inflammation0.53757596
152MP0001502_abnormal_circadian_rhythm0.51968556
153MP0000467_abnormal_esophagus_morphology0.48727610
154MP0002229_neurodegeneration0.47549999
155MP0005391_vision/eye_phenotype0.46168713
156MP0002135_abnormal_kidney_morphology0.44584456
157MP0009703_decreased_birth_body0.43696791
158MP0006036_abnormal_mitochondrial_physio0.41580756

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)7.88274945
2Absent/shortened dynein arms (HP:0200106)7.88274945
3Chronic bronchitis (HP:0004469)6.76005823
4Bronchiectasis (HP:0002110)5.88031307
5Recurrent sinusitis (HP:0011108)4.88353839
6Pancreatic fibrosis (HP:0100732)4.35165783
7True hermaphroditism (HP:0010459)4.17240658
8Chronic sinusitis (HP:0011109)4.02553281
9Nasal polyposis (HP:0100582)4.02187223
10Esophageal neoplasm (HP:0100751)3.83261378
11Neoplasm of head and neck (HP:0012288)3.83261378
12Bronchitis (HP:0012387)3.59962892
13Nephronophthisis (HP:0000090)3.53169559
14Abnormality of the nasal mucosa (HP:0000433)3.41781459
15Chronic otitis media (HP:0000389)3.13397146
16Hyperactive renin-angiotensin system (HP:0000841)3.01960772
17Abnormality of dentin (HP:0010299)2.96657524
18Pancreatic cysts (HP:0001737)2.89195776
19Tubular atrophy (HP:0000092)2.84372557
20Abnormal biliary tract physiology (HP:0012439)2.82307560
21Bile duct proliferation (HP:0001408)2.82307560
22Tubulointerstitial nephritis (HP:0001970)2.72315878
23Occipital encephalocele (HP:0002085)2.72084231
24Abnormality of the renal medulla (HP:0100957)2.66576613
25Concave nail (HP:0001598)2.55642640
26Congenital hepatic fibrosis (HP:0002612)2.53446899
27Recurrent otitis media (HP:0000403)2.52473640
28Abnormality of midbrain morphology (HP:0002418)2.50884707
29Molar tooth sign on MRI (HP:0002419)2.50884707
30Cystic liver disease (HP:0006706)2.49463442
31Gait imbalance (HP:0002141)2.44610795
32Postaxial foot polydactyly (HP:0001830)2.40494360
33Congenital primary aphakia (HP:0007707)2.39552618
34Median cleft lip (HP:0000161)2.36809760
35Medial flaring of the eyebrow (HP:0010747)2.35724270
36Aplasia/Hypoplasia of the tongue (HP:0010295)2.27844327
37Chronic hepatic failure (HP:0100626)2.25955389
38Stage 5 chronic kidney disease (HP:0003774)2.25127414
39Nephrogenic diabetes insipidus (HP:0009806)2.06519612
40Abnormal ciliary motility (HP:0012262)13.2202373
41Abnormal respiratory motile cilium physiology (HP:0012261)12.9647875
42Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.5929370
43Rhinitis (HP:0012384)10.9089858
44Abnormal respiratory epithelium morphology (HP:0012253)10.1998989
45Abnormal respiratory motile cilium morphology (HP:0005938)10.1998989
46Decreased circulating renin level (HP:0003351)1.95465409
47Infertility (HP:0000789)1.93569098
48Male pseudohermaphroditism (HP:0000037)1.92414187
49Bell-shaped thorax (HP:0001591)1.92383679
50Tubulointerstitial abnormality (HP:0001969)1.91514854
51Genital tract atresia (HP:0001827)1.90507262
52Anencephaly (HP:0002323)1.90400540
53Neonatal short-limb short stature (HP:0008921)1.88252317
54Abnormality of permanent molar morphology (HP:0011071)1.88239352
55Abnormality of the dental root (HP:0006486)1.88239352
56Taurodontia (HP:0000679)1.88239352
57Sex reversal (HP:0012245)1.87844480
58Abnormal sex determination (HP:0012244)1.87844480
59Renal salt wasting (HP:0000127)1.86087433
60Sclerocornea (HP:0000647)1.85881141
61Back pain (HP:0003418)1.81703669
62Abnormality of the renal cortex (HP:0011035)1.80629305
63Absent rod-and cone-mediated responses on ERG (HP:0007688)1.78888612
64Preaxial hand polydactyly (HP:0001177)1.78751456
65Absent frontal sinuses (HP:0002688)1.78235416
66Polydipsia (HP:0001959)1.75170652
67Abnormal drinking behavior (HP:0030082)1.75170652
68Abnormality of molar morphology (HP:0011070)1.74193636
69Abnormality of molar (HP:0011077)1.74193636
70Abnormality of the dental pulp (HP:0006479)1.72522879
71Vaginal atresia (HP:0000148)1.70943093
72Abdominal situs inversus (HP:0003363)1.66814508
73Abnormality of abdominal situs (HP:0011620)1.66814508
74Poor coordination (HP:0002370)1.65954301
75Hyperkalemia (HP:0002153)1.64897682
76Atelectasis (HP:0100750)1.62803081
77Postaxial hand polydactyly (HP:0001162)1.62239032
78Bronchomalacia (HP:0002780)1.60015530
79Supernumerary spleens (HP:0009799)1.55403486
80Hyperaldosteronism (HP:0000859)1.53662718
81Fibular hypoplasia (HP:0003038)1.52499126
82Furrowed tongue (HP:0000221)1.52101765
83Facial cleft (HP:0002006)1.49435916
84Recurrent bronchitis (HP:0002837)1.49267605
85Hypotelorism (HP:0000601)1.46256612
86Asplenia (HP:0001746)1.44603635
87Aplasia/Hypoplasia of the lens (HP:0008063)1.43110001
88Abnormality of renin-angiotensin system (HP:0000847)1.42488615
89Abnormality of chloride homeostasis (HP:0011422)1.42214893
90Onycholysis (HP:0001806)1.41933442
91Tubulointerstitial fibrosis (HP:0005576)1.39082977
92Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.36905425
93Decreased central vision (HP:0007663)1.36761507
94Male infertility (HP:0003251)1.35948707
95Hypokalemic alkalosis (HP:0001949)1.34628155
96Oculomotor apraxia (HP:0000657)1.31818261
97Short nail (HP:0001799)1.31556583
98Aplasia/Hypoplasia of the spleen (HP:0010451)1.28422686
99Ectopic anus (HP:0004397)1.27789594
100Abnormal rod and cone electroretinograms (HP:0008323)1.25799165
101Broad distal phalanx of finger (HP:0009836)1.23528837
102Short thorax (HP:0010306)1.22493760
103Abnormality of the fetal cardiovascular system (HP:0010948)1.22286201
104Abnormal umbilical cord blood vessels (HP:0011403)1.22286201
105Single umbilical artery (HP:0001195)1.22286201
106Cone-rod dystrophy (HP:0000548)1.21979740
107Glucose intolerance (HP:0000833)1.21413729
108Papilledema (HP:0001085)1.20996589
109Hypodontia (HP:0000668)1.15359204
110Bifid scrotum (HP:0000048)1.12844637
111Hyponatremia (HP:0002902)1.11395821
112Specific learning disability (HP:0001328)1.10463652
113Nephropathy (HP:0000112)1.10231420
114Hand muscle atrophy (HP:0009130)1.09863336
115Femoral bowing (HP:0002980)1.09606131
116Abnormality of the frontal sinuses (HP:0002687)1.09453843
117Polycystic kidney dysplasia (HP:0000113)1.08520828
118Polyuria (HP:0000103)1.08007934
119Abnormality of the distal phalanges of the toes (HP:0010182)1.07151633
120Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.07099838
121Abnormal urine output (HP:0012590)1.05765616
122Abnormality of macular pigmentation (HP:0008002)1.04924977
123Polycystic ovaries (HP:0000147)1.04544036
124Carpal bone hypoplasia (HP:0001498)1.01976456
125Narrow chest (HP:0000774)1.01825170
126Retinitis pigmentosa (HP:0000510)1.00202135
127Fetal akinesia sequence (HP:0001989)0.99369662
128Short femoral neck (HP:0100864)0.97528611
129Aplasia of the musculature (HP:0100854)0.95863371
130Abnormality of monocarboxylic acid metabolism (HP:0010996)0.95523475

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK158.73488122
2PNCK6.75563492
3EPHA24.69667098
4MST43.41482204
5MKNK23.06604370
6SIK13.05499471
7GRK12.65441990
8MAPKAPK32.54568920
9NME12.37278877
10STK242.02783942
11NTRK22.01589923
12MAP3K21.95448375
13TTK1.84007734
14MKNK11.78045573
15CASK1.65772516
16SMG11.65721529
17EEF2K1.51803574
18PAK21.50898163
19MAP3K31.44079863
20TLK11.42359359
21WEE11.41932543
22VRK11.23655686
23FES1.21644014
24ROCK21.15702452
25NEK61.15564792
26TRPM71.13735494
27GSK3A1.10675304
28EPHA31.06064890
29RPS6KA20.99483550
30BLK0.98053311
31PTK2B0.97404599
32LMTK20.94863755
33MAPKAPK50.94281058
34PRKCI0.93382737
35MAP3K90.92783759
36RIPK40.92056317
37MST1R0.91676085
38MAP3K70.90118414
39BRSK20.88846841
40PRKCG0.87865828
41ERBB30.86559060
42CDK30.82815709
43TBK10.82678095
44PKN10.81091201
45FER0.80173972
46DAPK20.79356232
47MAP2K70.79002093
48EPHA40.77966221
49FRK0.76758823
50MARK20.76640211
51STK160.75381548
52DYRK30.73584893
53BCR0.73332685
54ROCK10.72850370
55MAP3K120.71990820
56PAK30.71787883
57MAP3K40.71024740
58ITK0.70979229
59SIK20.70723030
60ARAF0.69953828
61OXSR10.69394620
62MUSK0.69258158
63ERBB20.68863463
64SGK4940.68400440
65SGK2230.68400440
66TEC0.68264995
67MAP2K20.67960321
68MARK10.67757292
69CAMK2B0.67285323
70MAPK120.67014868
71STK380.66190607
72CAMK2A0.66137862
73STK38L0.66096710
74NTRK30.65521570
75TESK10.64656528
76PRKG20.64268678
77PRKCE0.62949909
78NLK0.62468850
79DYRK20.62447517
80LATS10.61370317
81STK390.61006045
82PRKG10.60424893
83STK110.58616798
84STK100.57826173
85CSK0.56488181
86IRAK10.56335212
87MINK10.55789979
88LRRK20.55194589
89INSRR0.54982687
90GRK60.54880144
91PTK20.54029124
92PTK60.53088557
93PRKCQ0.52731490
94PRKACA0.52582496
95GRK50.52319522
96DYRK1A0.52134939
97AKT20.51410913
98HIPK20.49835081
99MAPKAPK20.49630508
100ADRBK20.48701844
101SRC0.47907762
102TIE10.47370049
103EPHB10.47240554
104CSNK1E0.46892744
105AURKA0.46356613
106CDC42BPA0.46185881
107PRKAA20.45016008
108DMPK0.44989210
109ADRBK10.44988821
110PRKCD0.44980896
111DDR20.44823104
112CAMK2D0.43721606
113MAPK130.43480188
114PRKACG0.43440171
115CDK50.42915805
116CAMKK20.42899284
117CAMK1G0.41715813
118CSNK1G10.41687200
119PHKG10.40796596
120PHKG20.40796596
121PBK0.40765362
122MOS0.40235208
123CAMK2G0.39188285
124FYN0.39020613
125MYLK0.38792035
126MAP4K20.37923297
127ABL10.37909462
128RPS6KC10.37620211
129RPS6KL10.37620211
130TNIK0.37074743
131RPS6KA40.36832215
132SGK10.36340750
133RPS6KB20.35843185
134MAPK40.33953303
135RPS6KA50.33584791
136EGFR0.32344918
137CAMKK10.32299782
138DYRK1B0.27082766
139PDPK10.25844285
140PRKCA0.25437502
141TAOK10.25270855
142MAP2K40.24020536
143BMPR20.23407111
144WNK40.23324598
145FGFR30.23048556
146ICK0.21958565
147ZAP700.21093003
148NEK90.17049091
149ACVR1B0.16935019
150PASK0.16212732
151PLK10.15926636
152TYK20.15199422
153CHEK20.12772527
154WNK30.12069390
155PRKCZ0.11731189
156CDK60.11554431

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003604.81542785
2Tyrosine metabolism_Homo sapiens_hsa003503.89106529
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.32571124
4beta-Alanine metabolism_Homo sapiens_hsa004103.04308893
5Huntingtons disease_Homo sapiens_hsa050162.94570280
6Caffeine metabolism_Homo sapiens_hsa002322.59444178
7Nitrogen metabolism_Homo sapiens_hsa009102.58004504
8Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.28796437
9Linoleic acid metabolism_Homo sapiens_hsa005912.07829062
10Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.05245647
11Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.95351832
12Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.93995142
13Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.90185882
14GABAergic synapse_Homo sapiens_hsa047271.85858305
15Fatty acid elongation_Homo sapiens_hsa000621.80375857
16Oxidative phosphorylation_Homo sapiens_hsa001901.79053150
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.77561821
18Histidine metabolism_Homo sapiens_hsa003401.76919408
19Gastric acid secretion_Homo sapiens_hsa049711.66410355
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.66117416
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.65906178
22Vitamin B6 metabolism_Homo sapiens_hsa007501.57966069
23Sphingolipid metabolism_Homo sapiens_hsa006001.56964332
24Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.52532740
25Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.49972539
26Glutamatergic synapse_Homo sapiens_hsa047241.47777805
27Butanoate metabolism_Homo sapiens_hsa006501.47769753
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.47318371
29Circadian entrainment_Homo sapiens_hsa047131.44291597
30Circadian rhythm_Homo sapiens_hsa047101.43651511
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.41734099
32Insulin secretion_Homo sapiens_hsa049111.41339004
33Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.38409999
34Glutathione metabolism_Homo sapiens_hsa004801.37955749
35PPAR signaling pathway_Homo sapiens_hsa033201.37662719
36Olfactory transduction_Homo sapiens_hsa047401.37039387
37Alzheimers disease_Homo sapiens_hsa050101.36146880
38Nicotine addiction_Homo sapiens_hsa050331.35466041
39Phototransduction_Homo sapiens_hsa047441.30552288
40Fatty acid degradation_Homo sapiens_hsa000711.27286067
41Ether lipid metabolism_Homo sapiens_hsa005651.26518782
42Taste transduction_Homo sapiens_hsa047421.25919112
43Amphetamine addiction_Homo sapiens_hsa050311.24516915
44Tight junction_Homo sapiens_hsa045301.22480975
45Chemical carcinogenesis_Homo sapiens_hsa052041.22340844
46Collecting duct acid secretion_Homo sapiens_hsa049661.21507724
47Bile secretion_Homo sapiens_hsa049761.21240951
48Ovarian steroidogenesis_Homo sapiens_hsa049131.20902535
49Renin secretion_Homo sapiens_hsa049241.18612559
50Parkinsons disease_Homo sapiens_hsa050121.16304226
51Salivary secretion_Homo sapiens_hsa049701.15168240
52Thyroid hormone synthesis_Homo sapiens_hsa049181.14001932
53Estrogen signaling pathway_Homo sapiens_hsa049151.13814137
54Cardiac muscle contraction_Homo sapiens_hsa042601.13762561
55Cocaine addiction_Homo sapiens_hsa050301.12622073
56Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.07181851
57Morphine addiction_Homo sapiens_hsa050321.05201808
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.04775896
59Calcium signaling pathway_Homo sapiens_hsa040201.04309088
60Basal cell carcinoma_Homo sapiens_hsa052171.01512047
61Melanogenesis_Homo sapiens_hsa049161.00070255
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97293731
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.96301832
64Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94934606
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.91756548
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.91393709
67Complement and coagulation cascades_Homo sapiens_hsa046100.89886825
68Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.89618995
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.88535688
70Starch and sucrose metabolism_Homo sapiens_hsa005000.87827936
71Peroxisome_Homo sapiens_hsa041460.87601883
72cAMP signaling pathway_Homo sapiens_hsa040240.87102924
73Aldosterone synthesis and secretion_Homo sapiens_hsa049250.86808954
74Serotonergic synapse_Homo sapiens_hsa047260.85537034
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.85157328
76Dorso-ventral axis formation_Homo sapiens_hsa043200.85081448
77Dilated cardiomyopathy_Homo sapiens_hsa054140.82380689
78Prion diseases_Homo sapiens_hsa050200.81280165
79GnRH signaling pathway_Homo sapiens_hsa049120.79358999
80Drug metabolism - other enzymes_Homo sapiens_hsa009830.78342195
81Mineral absorption_Homo sapiens_hsa049780.75465010
82Pancreatic secretion_Homo sapiens_hsa049720.74417053
83Hedgehog signaling pathway_Homo sapiens_hsa043400.73779794
84Retinol metabolism_Homo sapiens_hsa008300.73709833
85Cholinergic synapse_Homo sapiens_hsa047250.73160362
86Oxytocin signaling pathway_Homo sapiens_hsa049210.71700090
87Tryptophan metabolism_Homo sapiens_hsa003800.71662631
88Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.69624983
89Wnt signaling pathway_Homo sapiens_hsa043100.68449077
90cGMP-PKG signaling pathway_Homo sapiens_hsa040220.67830157
91Protein export_Homo sapiens_hsa030600.67538963
92Axon guidance_Homo sapiens_hsa043600.67263296
93Gap junction_Homo sapiens_hsa045400.66002074
94Propanoate metabolism_Homo sapiens_hsa006400.65155244
95Sulfur metabolism_Homo sapiens_hsa009200.64720891
96Dopaminergic synapse_Homo sapiens_hsa047280.64056152
97Hematopoietic cell lineage_Homo sapiens_hsa046400.63402126
98Phagosome_Homo sapiens_hsa041450.62158523
99Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61130028
100Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.60695708
101Long-term potentiation_Homo sapiens_hsa047200.60065824
102Leukocyte transendothelial migration_Homo sapiens_hsa046700.59205435
103Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.57967719
104Purine metabolism_Homo sapiens_hsa002300.57502351
105Hepatitis C_Homo sapiens_hsa051600.57464387
106Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56796921
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.56264931
108Graft-versus-host disease_Homo sapiens_hsa053320.55959044
109Arginine biosynthesis_Homo sapiens_hsa002200.55945123
110Type I diabetes mellitus_Homo sapiens_hsa049400.55606135
111Intestinal immune network for IgA production_Homo sapiens_hsa046720.54028139
112Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53277502
113ECM-receptor interaction_Homo sapiens_hsa045120.52484814
114Maturity onset diabetes of the young_Homo sapiens_hsa049500.51818852
115Long-term depression_Homo sapiens_hsa047300.51327864
116Rheumatoid arthritis_Homo sapiens_hsa053230.50796660
117Synaptic vesicle cycle_Homo sapiens_hsa047210.49931713
118Allograft rejection_Homo sapiens_hsa053300.49432391
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.49174027
120Hippo signaling pathway_Homo sapiens_hsa043900.48803814
121Asthma_Homo sapiens_hsa053100.47947145
122Choline metabolism in cancer_Homo sapiens_hsa052310.46242457
123Arachidonic acid metabolism_Homo sapiens_hsa005900.46071279
124Vibrio cholerae infection_Homo sapiens_hsa051100.45897412
125Autoimmune thyroid disease_Homo sapiens_hsa053200.44170788
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43529156
127Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.42077087
128ABC transporters_Homo sapiens_hsa020100.41930188
129Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.41893050
130alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38129133
131Metabolic pathways_Homo sapiens_hsa011000.36418096
132Transcriptional misregulation in cancer_Homo sapiens_hsa052020.36004452
133Antigen processing and presentation_Homo sapiens_hsa046120.35724934
134Notch signaling pathway_Homo sapiens_hsa043300.34634121
135Cyanoamino acid metabolism_Homo sapiens_hsa004600.34552026
136Vitamin digestion and absorption_Homo sapiens_hsa049770.30516164
137Glycerolipid metabolism_Homo sapiens_hsa005610.30066780
138Arginine and proline metabolism_Homo sapiens_hsa003300.26859040
139Adherens junction_Homo sapiens_hsa045200.25143858
140Lysosome_Homo sapiens_hsa041420.24993848
141Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23867315
142Jak-STAT signaling pathway_Homo sapiens_hsa046300.23497139
143Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.21325199
144Regulation of autophagy_Homo sapiens_hsa041400.20843656
145Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.19374438
146Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.18680860
147Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.15304482
148RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.14170219
149Amoebiasis_Homo sapiens_hsa051460.14000099
150Fatty acid biosynthesis_Homo sapiens_hsa000610.11252867
151Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.10428982
152Sphingolipid signaling pathway_Homo sapiens_hsa040710.10020105
153Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.09157460

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