

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | piRNA metabolic process (GO:0034587) | 8.76116219 |
| 2 | NIK/NF-kappaB signaling (GO:0038061) | 7.41655854 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 5.97635539 |
| 4 | DNA methylation involved in gamete generation (GO:0043046) | 5.76441632 |
| 5 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 5.18153795 |
| 6 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 5.01918586 |
| 7 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 5.01918586 |
| 8 | gonadal mesoderm development (GO:0007506) | 5.00580459 |
| 9 | centriole assembly (GO:0098534) | 4.91935803 |
| 10 | poly(A)+ mRNA export from nucleus (GO:0016973) | 4.80861778 |
| 11 | centriole replication (GO:0007099) | 4.70769161 |
| 12 | viral transcription (GO:0019083) | 4.70661700 |
| 13 | ribosomal small subunit biogenesis (GO:0042274) | 4.65149546 |
| 14 | ribosomal large subunit biogenesis (GO:0042273) | 4.63061657 |
| 15 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.54869865 |
| 16 | translational termination (GO:0006415) | 4.54555348 |
| 17 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.48656157 |
| 18 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.47132069 |
| 19 | meiotic chromosome segregation (GO:0045132) | 4.46944868 |
| 20 | cotranslational protein targeting to membrane (GO:0006613) | 4.40108103 |
| 21 | protein targeting to ER (GO:0045047) | 4.38881450 |
| 22 | I-kappaB phosphorylation (GO:0007252) | 4.28604689 |
| 23 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.22631452 |
| 24 | regulation of mitochondrial translation (GO:0070129) | 4.21760660 |
| 25 | protein localization to endoplasmic reticulum (GO:0070972) | 4.14486520 |
| 26 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 4.07092949 |
| 27 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.91635084 |
| 28 | translational initiation (GO:0006413) | 3.83794619 |
| 29 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.81807587 |
| 30 | coenzyme A biosynthetic process (GO:0015937) | 3.80888640 |
| 31 | translational elongation (GO:0006414) | 3.78054985 |
| 32 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.64171056 |
| 33 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.63041035 |
| 34 | daunorubicin metabolic process (GO:0044597) | 3.60654412 |
| 35 | polyketide metabolic process (GO:0030638) | 3.60654412 |
| 36 | doxorubicin metabolic process (GO:0044598) | 3.60654412 |
| 37 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.55167456 |
| 38 | viral life cycle (GO:0019058) | 3.50255572 |
| 39 | positive regulation by symbiont of host defense response (GO:0052509) | 3.48274675 |
| 40 | modulation by symbiont of host defense response (GO:0052031) | 3.48274675 |
| 41 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.48274675 |
| 42 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.48274675 |
| 43 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.48274675 |
| 44 | modulation by symbiont of host immune response (GO:0052553) | 3.48274675 |
| 45 | maturation of 5.8S rRNA (GO:0000460) | 3.45196309 |
| 46 | B cell proliferation (GO:0042100) | 3.37618017 |
| 47 | cellular protein complex disassembly (GO:0043624) | 3.34191590 |
| 48 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.28608973 |
| 49 | gene silencing by RNA (GO:0031047) | 3.27738627 |
| 50 | mitochondrion morphogenesis (GO:0070584) | 3.23043365 |
| 51 | pyrimidine dimer repair (GO:0006290) | 3.21620890 |
| 52 | negative regulation of DNA repair (GO:0045738) | 3.19935194 |
| 53 | formation of translation preinitiation complex (GO:0001731) | 3.17702914 |
| 54 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.17286346 |
| 55 | aminoglycoside antibiotic metabolic process (GO:0030647) | 3.17222798 |
| 56 | resolution of meiotic recombination intermediates (GO:0000712) | 3.14785801 |
| 57 | cranial suture morphogenesis (GO:0060363) | 3.13260941 |
| 58 | pantothenate metabolic process (GO:0015939) | 3.13242417 |
| 59 | segment specification (GO:0007379) | 3.11211661 |
| 60 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.09414179 |
| 61 | embryonic viscerocranium morphogenesis (GO:0048703) | 3.09252169 |
| 62 | establishment of integrated proviral latency (GO:0075713) | 3.05515067 |
| 63 | lipopolysaccharide biosynthetic process (GO:0009103) | 3.01290122 |
| 64 | protein neddylation (GO:0045116) | 2.97992092 |
| 65 | respiratory chain complex IV assembly (GO:0008535) | 2.96544301 |
| 66 | purine nucleoside bisphosphate biosynthetic process (GO:0034033) | 2.96272111 |
| 67 | ribonucleoside bisphosphate biosynthetic process (GO:0034030) | 2.96272111 |
| 68 | nucleoside bisphosphate biosynthetic process (GO:0033866) | 2.96272111 |
| 69 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.94223395 |
| 70 | protein targeting to membrane (GO:0006612) | 2.91646477 |
| 71 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.91645060 |
| 72 | translation (GO:0006412) | 2.91521918 |
| 73 | inner mitochondrial membrane organization (GO:0007007) | 2.90622870 |
| 74 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.84237915 |
| 75 | regulation of acrosome reaction (GO:0060046) | 2.84091655 |
| 76 | establishment of viral latency (GO:0019043) | 2.81742408 |
| 77 | synaptonemal complex assembly (GO:0007130) | 2.80651464 |
| 78 | protein complex disassembly (GO:0043241) | 2.80051436 |
| 79 | aerobic respiration (GO:0009060) | 2.77124943 |
| 80 | exocrine pancreas development (GO:0031017) | 2.76270602 |
| 81 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.72426588 |
| 82 | electron transport chain (GO:0022900) | 2.72055216 |
| 83 | respiratory electron transport chain (GO:0022904) | 2.70921988 |
| 84 | macromolecular complex disassembly (GO:0032984) | 2.70831527 |
| 85 | mannosylation (GO:0097502) | 2.69561887 |
| 86 | motile cilium assembly (GO:0044458) | 2.69067174 |
| 87 | cytochrome complex assembly (GO:0017004) | 2.62864440 |
| 88 | craniofacial suture morphogenesis (GO:0097094) | 2.61575826 |
| 89 | lung-associated mesenchyme development (GO:0060484) | 2.61087656 |
| 90 | regulation of helicase activity (GO:0051095) | 2.59414322 |
| 91 | cellular component biogenesis (GO:0044085) | 2.57757493 |
| 92 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.56976456 |
| 93 | GDP-mannose metabolic process (GO:0019673) | 2.55689822 |
| 94 | DNA synthesis involved in DNA repair (GO:0000731) | 2.55178442 |
| 95 | galactose metabolic process (GO:0006012) | 2.54942907 |
| 96 | CENP-A containing nucleosome assembly (GO:0034080) | 2.54817954 |
| 97 | anterior/posterior axis specification, embryo (GO:0008595) | 2.53381780 |
| 98 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.52944375 |
| 99 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.52625570 |
| 100 | proteasome assembly (GO:0043248) | 2.51213174 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.42861539 |
| 2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.37093887 |
| 3 | ZNF263_19887448_ChIP-Seq_K562_Human | 4.33773407 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.76566520 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.23515087 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.20091861 |
| 7 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.07958235 |
| 8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.06648129 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.96431057 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.90687832 |
| 11 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.86736645 |
| 12 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.62151811 |
| 13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.60380235 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.53457614 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.52198852 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.51879674 |
| 17 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.47156298 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.42709627 |
| 19 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.39005279 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.36126465 |
| 21 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.27114584 |
| 22 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.26118721 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.25088967 |
| 24 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.24200653 |
| 25 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 2.19277107 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.15759068 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.11135814 |
| 28 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.07483389 |
| 29 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.05529625 |
| 30 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.97992381 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.88432008 |
| 32 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.83895941 |
| 33 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.79795164 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.78585723 |
| 35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.76328813 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.71447116 |
| 37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.67892421 |
| 38 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.63764798 |
| 39 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.63490317 |
| 40 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.59599448 |
| 41 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.59591010 |
| 42 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.55673523 |
| 43 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.55575048 |
| 44 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.53969421 |
| 45 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.53117330 |
| 46 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.50107558 |
| 47 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.48434995 |
| 48 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.45244323 |
| 49 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.42165385 |
| 50 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.39278210 |
| 51 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.38707597 |
| 52 | FUS_26573619_Chip-Seq_HEK293_Human | 1.38427124 |
| 53 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.37659817 |
| 54 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.36220925 |
| 55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35601134 |
| 56 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.35140176 |
| 57 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.31416782 |
| 58 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.29262699 |
| 59 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.28264198 |
| 60 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.26787732 |
| 61 | EOMES_21245162_ChIP-Seq_HESCs_Human | 1.26565818 |
| 62 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.24801935 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.21861160 |
| 64 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.21209280 |
| 65 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.20965977 |
| 66 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19399496 |
| 67 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.17847327 |
| 68 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.17727202 |
| 69 | EWS_26573619_Chip-Seq_HEK293_Human | 1.14694305 |
| 70 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.13097078 |
| 71 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11044545 |
| 72 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.09876364 |
| 73 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.07349011 |
| 74 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07339982 |
| 75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06521578 |
| 76 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.05156440 |
| 77 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.01797144 |
| 78 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.99639430 |
| 79 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.99386072 |
| 80 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.97840082 |
| 81 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97144313 |
| 82 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97144313 |
| 83 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95017574 |
| 84 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.93615401 |
| 85 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.93378743 |
| 86 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92303801 |
| 87 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.89282713 |
| 88 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.87481452 |
| 89 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.86410375 |
| 90 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.85846329 |
| 91 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.85275901 |
| 92 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.83502433 |
| 93 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.83132334 |
| 94 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.82495319 |
| 95 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.82339149 |
| 96 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.82150797 |
| 97 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.81057258 |
| 98 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.80516379 |
| 99 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.80472003 |
| 100 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.79485894 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 5.40999269 |
| 2 | MP0002102_abnormal_ear_morphology | 5.05644974 |
| 3 | MP0002138_abnormal_hepatobiliary_system | 4.25673470 |
| 4 | MP0001348_abnormal_lacrimal_gland | 4.02607404 |
| 5 | MP0005379_endocrine/exocrine_gland_phen | 3.32430682 |
| 6 | MP0003890_abnormal_embryonic-extraembry | 3.05811111 |
| 7 | MP0008995_early_reproductive_senescence | 2.96664525 |
| 8 | MP0010030_abnormal_orbit_morphology | 2.83991516 |
| 9 | MP0001661_extended_life_span | 2.65647193 |
| 10 | MP0003183_abnormal_peptide_metabolism | 2.65211543 |
| 11 | MP0002638_abnormal_pupillary_reflex | 2.34709556 |
| 12 | MP0003786_premature_aging | 2.12300256 |
| 13 | MP0002163_abnormal_gland_morphology | 2.03345536 |
| 14 | MP0004133_heterotaxia | 1.91171420 |
| 15 | MP0004957_abnormal_blastocyst_morpholog | 1.89791409 |
| 16 | MP0003950_abnormal_plasma_membrane | 1.79193035 |
| 17 | MP0006292_abnormal_olfactory_placode | 1.77778666 |
| 18 | MP0008058_abnormal_DNA_repair | 1.72641744 |
| 19 | MP0001529_abnormal_vocalization | 1.65719140 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.65013552 |
| 21 | MP0009384_cardiac_valve_regurgitation | 1.63983487 |
| 22 | MP0000537_abnormal_urethra_morphology | 1.61547471 |
| 23 | MP0002210_abnormal_sex_determination | 1.61492165 |
| 24 | MP0001764_abnormal_homeostasis | 1.60870851 |
| 25 | MP0003077_abnormal_cell_cycle | 1.57783109 |
| 26 | MP0000015_abnormal_ear_pigmentation | 1.54572761 |
| 27 | MP0000383_abnormal_hair_follicle | 1.52388428 |
| 28 | MP0003252_abnormal_bile_duct | 1.51429312 |
| 29 | MP0005257_abnormal_intraocular_pressure | 1.50618546 |
| 30 | MP0001727_abnormal_embryo_implantation | 1.49224672 |
| 31 | MP0002928_abnormal_bile_duct | 1.47748356 |
| 32 | MP0003119_abnormal_digestive_system | 1.42469561 |
| 33 | MP0005187_abnormal_penis_morphology | 1.40376464 |
| 34 | MP0001145_abnormal_male_reproductive | 1.32975249 |
| 35 | MP0004264_abnormal_extraembryonic_tissu | 1.28437392 |
| 36 | MP0003718_maternal_effect | 1.27980435 |
| 37 | MP0000653_abnormal_sex_gland | 1.20935079 |
| 38 | MP0000428_abnormal_craniofacial_morphol | 1.18449322 |
| 39 | MP0003195_calcinosis | 1.11275968 |
| 40 | MP0000762_abnormal_tongue_morphology | 1.09422651 |
| 41 | MP0005380_embryogenesis_phenotype | 1.08796577 |
| 42 | MP0001672_abnormal_embryogenesis/_devel | 1.08796577 |
| 43 | MP0001929_abnormal_gametogenesis | 1.08578785 |
| 44 | MP0010678_abnormal_skin_adnexa | 1.06911422 |
| 45 | MP0003984_embryonic_growth_retardation | 1.06894063 |
| 46 | MP0010094_abnormal_chromosome_stability | 1.06319458 |
| 47 | MP0002088_abnormal_embryonic_growth/wei | 1.06051730 |
| 48 | MP0002254_reproductive_system_inflammat | 1.04193572 |
| 49 | MP0010368_abnormal_lymphatic_system | 1.03367090 |
| 50 | MP0002233_abnormal_nose_morphology | 1.01610677 |
| 51 | MP0003698_abnormal_male_reproductive | 1.00322657 |
| 52 | MP0003315_abnormal_perineum_morphology | 0.98125839 |
| 53 | MP0000647_abnormal_sebaceous_gland | 0.97630074 |
| 54 | MP0000490_abnormal_crypts_of | 0.97123775 |
| 55 | MP0001915_intracranial_hemorrhage | 0.96863347 |
| 56 | MP0004233_abnormal_muscle_weight | 0.95937683 |
| 57 | MP0001286_abnormal_eye_development | 0.94048899 |
| 58 | MP0002160_abnormal_reproductive_system | 0.92941759 |
| 59 | MP0000462_abnormal_digestive_system | 0.92680525 |
| 60 | MP0001697_abnormal_embryo_size | 0.91451985 |
| 61 | MP0009379_abnormal_foot_pigmentation | 0.90219787 |
| 62 | MP0005501_abnormal_skin_physiology | 0.89777412 |
| 63 | MP0002653_abnormal_ependyma_morphology | 0.88733967 |
| 64 | MP0002837_dystrophic_cardiac_calcinosis | 0.87191035 |
| 65 | MP0001270_distended_abdomen | 0.86785304 |
| 66 | MP0002139_abnormal_hepatobiliary_system | 0.85140688 |
| 67 | MP0010329_abnormal_lipoprotein_level | 0.84854239 |
| 68 | MP0003123_paternal_imprinting | 0.84482879 |
| 69 | MP0006035_abnormal_mitochondrial_morpho | 0.84223494 |
| 70 | MP0002132_abnormal_respiratory_system | 0.83621155 |
| 71 | MP0002127_abnormal_cardiovascular_syste | 0.83495010 |
| 72 | MP0005394_taste/olfaction_phenotype | 0.82694801 |
| 73 | MP0005499_abnormal_olfactory_system | 0.82694801 |
| 74 | MP0005083_abnormal_biliary_tract | 0.80603300 |
| 75 | MP0010386_abnormal_urinary_bladder | 0.78689884 |
| 76 | MP0001324_abnormal_eye_pigmentation | 0.78167927 |
| 77 | MP0008875_abnormal_xenobiotic_pharmacok | 0.76656162 |
| 78 | MP0005551_abnormal_eye_electrophysiolog | 0.76565905 |
| 79 | MP0002085_abnormal_embryonic_tissue | 0.73562909 |
| 80 | MP0001968_abnormal_touch/_nociception | 0.71776711 |
| 81 | MP0006036_abnormal_mitochondrial_physio | 0.71160447 |
| 82 | MP0005408_hypopigmentation | 0.70842249 |
| 83 | MP0004147_increased_porphyrin_level | 0.70588278 |
| 84 | MP0002084_abnormal_developmental_patter | 0.70093168 |
| 85 | MP0005389_reproductive_system_phenotype | 0.69559086 |
| 86 | MP0001299_abnormal_eye_distance/ | 0.69367883 |
| 87 | MP0004808_abnormal_hematopoietic_stem | 0.67156657 |
| 88 | MP0003755_abnormal_palate_morphology | 0.66965558 |
| 89 | MP0003136_yellow_coat_color | 0.66856834 |
| 90 | MP0002086_abnormal_extraembryonic_tissu | 0.65510523 |
| 91 | MP0001346_abnormal_lacrimal_gland | 0.65349628 |
| 92 | MP0002736_abnormal_nociception_after | 0.63553005 |
| 93 | MP0002796_impaired_skin_barrier | 0.63313161 |
| 94 | MP0002090_abnormal_vision | 0.62411960 |
| 95 | MP0003045_fibrosis | 0.60150721 |
| 96 | MP0003638_abnormal_response/metabolism_ | 0.59981227 |
| 97 | MP0002295_abnormal_pulmonary_circulatio | 0.59822290 |
| 98 | MP0001919_abnormal_reproductive_system | 0.58906306 |
| 99 | MP0004197_abnormal_fetal_growth/weight/ | 0.58818079 |
| 100 | MP0003938_abnormal_ear_development | 0.58478281 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 5.13245417 |
| 2 | Hypobetalipoproteinemia (HP:0003563) | 5.05354359 |
| 3 | Microvesicular hepatic steatosis (HP:0001414) | 4.49317979 |
| 4 | Acanthocytosis (HP:0001927) | 4.44309315 |
| 5 | Visual hallucinations (HP:0002367) | 4.37288215 |
| 6 | Type I transferrin isoform profile (HP:0003642) | 3.72930158 |
| 7 | Nonimmune hydrops fetalis (HP:0001790) | 3.72706918 |
| 8 | Hypoplasia of the pons (HP:0012110) | 3.66206724 |
| 9 | Agammaglobulinemia (HP:0004432) | 3.50349099 |
| 10 | Atonic seizures (HP:0010819) | 3.50324920 |
| 11 | Dyschromatopsia (HP:0007641) | 3.31164477 |
| 12 | Testicular atrophy (HP:0000029) | 3.29673371 |
| 13 | Hypolipoproteinemia (HP:0010981) | 3.28492702 |
| 14 | Abnormal protein glycosylation (HP:0012346) | 3.27646831 |
| 15 | Abnormal glycosylation (HP:0012345) | 3.27646831 |
| 16 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.27646831 |
| 17 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.27646831 |
| 18 | Sensory axonal neuropathy (HP:0003390) | 3.25313630 |
| 19 | Absence seizures (HP:0002121) | 3.24796904 |
| 20 | Mixed hearing impairment (HP:0000410) | 3.16234036 |
| 21 | Focal motor seizures (HP:0011153) | 3.14072756 |
| 22 | Decreased muscle mass (HP:0003199) | 3.12953760 |
| 23 | Reduced antithrombin III activity (HP:0001976) | 3.10811117 |
| 24 | Abnormality of the pons (HP:0007361) | 3.06373295 |
| 25 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.05937278 |
| 26 | Abnormality of alanine metabolism (HP:0010916) | 3.05937278 |
| 27 | Hyperalaninemia (HP:0003348) | 3.05937278 |
| 28 | Dysphonia (HP:0001618) | 2.96340148 |
| 29 | Esophageal atresia (HP:0002032) | 2.90037736 |
| 30 | Poikiloderma (HP:0001029) | 2.70526284 |
| 31 | Global brain atrophy (HP:0002283) | 2.68987819 |
| 32 | Central scotoma (HP:0000603) | 2.66348449 |
| 33 | Recurrent bronchitis (HP:0002837) | 2.65391269 |
| 34 | Dyskinesia (HP:0100660) | 2.61239699 |
| 35 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.59602402 |
| 36 | Prolonged partial thromboplastin time (HP:0003645) | 2.54600363 |
| 37 | Methylmalonic acidemia (HP:0002912) | 2.53650267 |
| 38 | Progressive external ophthalmoplegia (HP:0000590) | 2.42889757 |
| 39 | Reticulocytopenia (HP:0001896) | 2.40329144 |
| 40 | Abnormality of the intrinsic pathway (HP:0010989) | 2.35880560 |
| 41 | Irregular epiphyses (HP:0010582) | 2.32937652 |
| 42 | Acute necrotizing encephalopathy (HP:0006965) | 2.29690835 |
| 43 | Scotoma (HP:0000575) | 2.26987410 |
| 44 | Mitochondrial inheritance (HP:0001427) | 2.26784317 |
| 45 | Hepatocellular necrosis (HP:0001404) | 2.26451815 |
| 46 | Abnormal auditory evoked potentials (HP:0006958) | 2.26447570 |
| 47 | Chromsome breakage (HP:0040012) | 2.24951152 |
| 48 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.24659439 |
| 49 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.24659439 |
| 50 | Concave nail (HP:0001598) | 2.21705733 |
| 51 | Broad distal phalanx of finger (HP:0009836) | 2.21508768 |
| 52 | Increased CSF lactate (HP:0002490) | 2.21105217 |
| 53 | Dialeptic seizures (HP:0011146) | 2.20274745 |
| 54 | Opisthotonus (HP:0002179) | 2.19795986 |
| 55 | Resting tremor (HP:0002322) | 2.11460212 |
| 56 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.11292236 |
| 57 | Freckling (HP:0001480) | 2.06996578 |
| 58 | Acute encephalopathy (HP:0006846) | 2.05327244 |
| 59 | Meckel diverticulum (HP:0002245) | 2.05187591 |
| 60 | Akinesia (HP:0002304) | 2.04651101 |
| 61 | Bronchitis (HP:0012387) | 2.01251769 |
| 62 | Hypergonadotropic hypogonadism (HP:0000815) | 1.98628605 |
| 63 | Nasolacrimal duct obstruction (HP:0000579) | 1.98168997 |
| 64 | Abnormality of methionine metabolism (HP:0010901) | 1.97751452 |
| 65 | Hepatic necrosis (HP:0002605) | 1.97591720 |
| 66 | Papillary thyroid carcinoma (HP:0002895) | 1.96942548 |
| 67 | Anteriorly placed anus (HP:0001545) | 1.95285980 |
| 68 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.95161369 |
| 69 | Abnormality of the ileum (HP:0001549) | 1.94584437 |
| 70 | Thrombocytosis (HP:0001894) | 1.90821018 |
| 71 | Increased hepatocellular lipid droplets (HP:0006565) | 1.90546939 |
| 72 | Abnormal ventriculo-arterial connection (HP:0011563) | 1.90455049 |
| 73 | Transposition of the great arteries (HP:0001669) | 1.90455049 |
| 74 | Abnormal connection of the cardiac segments (HP:0011545) | 1.90455049 |
| 75 | Broad nasal tip (HP:0000455) | 1.89802841 |
| 76 | Premature ovarian failure (HP:0008209) | 1.89349343 |
| 77 | Stenosis of the external auditory canal (HP:0000402) | 1.88701771 |
| 78 | Cerebral edema (HP:0002181) | 1.87217404 |
| 79 | Gliosis (HP:0002171) | 1.87047060 |
| 80 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.86491227 |
| 81 | Macrocytic anemia (HP:0001972) | 1.84984835 |
| 82 | Absent radius (HP:0003974) | 1.83866936 |
| 83 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.83545432 |
| 84 | Hyperglycinemia (HP:0002154) | 1.78569618 |
| 85 | Gastrointestinal atresia (HP:0002589) | 1.78516043 |
| 86 | Menstrual irregularities (HP:0000858) | 1.77218853 |
| 87 | Abnormality of vitamin B metabolism (HP:0004340) | 1.76306101 |
| 88 | CNS demyelination (HP:0007305) | 1.74514402 |
| 89 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.71738844 |
| 90 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.71738844 |
| 91 | Single umbilical artery (HP:0001195) | 1.71738844 |
| 92 | Rhabdomyolysis (HP:0003201) | 1.71441735 |
| 93 | Abnormality of the labia minora (HP:0012880) | 1.70530403 |
| 94 | Lipid accumulation in hepatocytes (HP:0006561) | 1.69836780 |
| 95 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.69824195 |
| 96 | Poor suck (HP:0002033) | 1.69652923 |
| 97 | Triphalangeal thumb (HP:0001199) | 1.67283859 |
| 98 | Abnormality of vitamin metabolism (HP:0100508) | 1.67175277 |
| 99 | Abnormality of the preputium (HP:0100587) | 1.66643549 |
| 100 | Carpal bone hypoplasia (HP:0001498) | 1.66532890 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PBK | 4.01623591 |
| 2 | MUSK | 3.50826660 |
| 3 | CDC7 | 3.48646003 |
| 4 | VRK2 | 3.34789443 |
| 5 | LATS1 | 3.34366676 |
| 6 | BRD4 | 3.22678260 |
| 7 | SCYL2 | 3.03612186 |
| 8 | MAP3K12 | 2.52745983 |
| 9 | NUAK1 | 2.46475123 |
| 10 | NME2 | 2.44972041 |
| 11 | MKNK1 | 2.15967922 |
| 12 | NEK2 | 2.15089857 |
| 13 | SMG1 | 2.11485202 |
| 14 | KDR | 1.94783731 |
| 15 | WNK3 | 1.91280777 |
| 16 | TAF1 | 1.84656007 |
| 17 | SRPK1 | 1.68254512 |
| 18 | STK3 | 1.64686154 |
| 19 | PRKD3 | 1.64195732 |
| 20 | MAP2K1 | 1.63168233 |
| 21 | BLK | 1.56111277 |
| 22 | ACVR1B | 1.52455759 |
| 23 | PNCK | 1.39268849 |
| 24 | TRIM28 | 1.37973174 |
| 25 | MST1R | 1.33883907 |
| 26 | MYLK | 1.32785527 |
| 27 | CASK | 1.30917770 |
| 28 | PKN2 | 1.30892655 |
| 29 | MAP2K3 | 1.30022799 |
| 30 | NEK1 | 1.29947324 |
| 31 | MAP3K4 | 1.28814885 |
| 32 | MST4 | 1.27708758 |
| 33 | CDK7 | 1.24577161 |
| 34 | ERBB3 | 1.20647773 |
| 35 | PLK4 | 1.20146519 |
| 36 | RPS6KB1 | 1.17757447 |
| 37 | FGFR1 | 1.13469888 |
| 38 | PASK | 1.05555725 |
| 39 | MAP3K8 | 0.97216614 |
| 40 | MKNK2 | 0.92785939 |
| 41 | CDK12 | 0.92215733 |
| 42 | MELK | 0.92017191 |
| 43 | FLT3 | 0.89656851 |
| 44 | MAP3K10 | 0.89501578 |
| 45 | CDK19 | 0.88629076 |
| 46 | MATK | 0.81699791 |
| 47 | LYN | 0.81566646 |
| 48 | ICK | 0.80291898 |
| 49 | BRSK2 | 0.75143572 |
| 50 | ALK | 0.75017282 |
| 51 | PIK3CA | 0.74975807 |
| 52 | MAP3K5 | 0.74661108 |
| 53 | SIK3 | 0.74458084 |
| 54 | CSNK2A1 | 0.72952328 |
| 55 | PRKG2 | 0.69466442 |
| 56 | MAP3K9 | 0.67913758 |
| 57 | AURKA | 0.67198490 |
| 58 | IKBKE | 0.65673987 |
| 59 | CSNK2A2 | 0.64978403 |
| 60 | EGFR | 0.64323645 |
| 61 | DYRK1B | 0.62845303 |
| 62 | DYRK2 | 0.62367381 |
| 63 | RPS6KA4 | 0.61727008 |
| 64 | CHEK1 | 0.60676137 |
| 65 | ADRBK1 | 0.58885721 |
| 66 | STK24 | 0.58026902 |
| 67 | STK16 | 0.57632933 |
| 68 | ERBB4 | 0.55217808 |
| 69 | MAP3K3 | 0.54056472 |
| 70 | BRSK1 | 0.53162520 |
| 71 | MAP2K7 | 0.52974181 |
| 72 | MAP2K4 | 0.52317515 |
| 73 | BMPR1B | 0.52219371 |
| 74 | PINK1 | 0.51591570 |
| 75 | PLK1 | 0.50031873 |
| 76 | CHEK2 | 0.49103915 |
| 77 | SYK | 0.46808892 |
| 78 | STK4 | 0.44931231 |
| 79 | RPS6KB2 | 0.43947358 |
| 80 | PAK2 | 0.43346206 |
| 81 | PRKG1 | 0.42978884 |
| 82 | ABL2 | 0.40285349 |
| 83 | DAPK3 | 0.39721176 |
| 84 | PDPK1 | 0.39532925 |
| 85 | VRK1 | 0.37444818 |
| 86 | PAK4 | 0.36707877 |
| 87 | NEK6 | 0.36594640 |
| 88 | FGFR2 | 0.35998281 |
| 89 | FYN | 0.35913654 |
| 90 | PRKCQ | 0.34106342 |
| 91 | AURKB | 0.33899535 |
| 92 | CSNK1D | 0.31174288 |
| 93 | ATR | 0.30671589 |
| 94 | MAPKAPK5 | 0.30631030 |
| 95 | PRPF4B | 0.30094966 |
| 96 | TGFBR1 | 0.28321719 |
| 97 | EPHA2 | 0.28079538 |
| 98 | TRPM7 | 0.26809823 |
| 99 | CDK2 | 0.24598594 |
| 100 | MAPK3 | 0.23446246 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.14546970 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.34413201 |
| 3 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 3.64535800 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.97575599 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.89380124 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.64534074 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.38509528 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.32991402 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.07666266 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.02918312 |
| 11 | RNA transport_Homo sapiens_hsa03013 | 2.00427398 |
| 12 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.89856936 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.70981624 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.69505183 |
| 15 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.64850495 |
| 16 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.61727070 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.61324507 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.60040858 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.58831800 |
| 20 | Sulfur relay system_Homo sapiens_hsa04122 | 1.54136087 |
| 21 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.48717848 |
| 22 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.47542935 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.46038865 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.45558240 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.43212448 |
| 26 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.40947548 |
| 27 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.39194269 |
| 28 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.38232842 |
| 29 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.34103702 |
| 30 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.33646104 |
| 31 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32269118 |
| 32 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.31264251 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.25843316 |
| 34 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.19193496 |
| 35 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.15831604 |
| 36 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.15533417 |
| 37 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.14313302 |
| 38 | Basal transcription factors_Homo sapiens_hsa03022 | 1.14195805 |
| 39 | Retinol metabolism_Homo sapiens_hsa00830 | 1.11322100 |
| 40 | Base excision repair_Homo sapiens_hsa03410 | 1.09717037 |
| 41 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.03038257 |
| 42 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.98963497 |
| 43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.97835285 |
| 44 | RNA degradation_Homo sapiens_hsa03018 | 0.96585545 |
| 45 | Phototransduction_Homo sapiens_hsa04744 | 0.95206500 |
| 46 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.92514792 |
| 47 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.90964939 |
| 48 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89991479 |
| 49 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.88663590 |
| 50 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.88317694 |
| 51 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.87221608 |
| 52 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.86290617 |
| 53 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.82270100 |
| 54 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.78642498 |
| 55 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.78353824 |
| 56 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.78315144 |
| 57 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.78225180 |
| 58 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.77657710 |
| 59 | Nicotine addiction_Homo sapiens_hsa05033 | 0.75864056 |
| 60 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.75159045 |
| 61 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.72157414 |
| 62 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.68513554 |
| 63 | Purine metabolism_Homo sapiens_hsa00230 | 0.68353770 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66967176 |
| 65 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.66142694 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65902288 |
| 67 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.65620267 |
| 68 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.64421240 |
| 69 | Cell cycle_Homo sapiens_hsa04110 | 0.62498555 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.61187476 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58584193 |
| 72 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.54754837 |
| 73 | Galactose metabolism_Homo sapiens_hsa00052 | 0.54222948 |
| 74 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.54213467 |
| 75 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.53779039 |
| 76 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.53718334 |
| 77 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.52059856 |
| 78 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.50762190 |
| 79 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50195571 |
| 80 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.48043364 |
| 81 | Peroxisome_Homo sapiens_hsa04146 | 0.45463339 |
| 82 | Asthma_Homo sapiens_hsa05310 | 0.44154953 |
| 83 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.40509798 |
| 84 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39808841 |
| 85 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.36295218 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35489717 |
| 87 | Colorectal cancer_Homo sapiens_hsa05210 | 0.34135762 |
| 88 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.33192741 |
| 89 | Thyroid cancer_Homo sapiens_hsa05216 | 0.30818770 |
| 90 | Adherens junction_Homo sapiens_hsa04520 | 0.28957421 |
| 91 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.28544545 |
| 92 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.28022356 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.27076318 |
| 94 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26478437 |
| 95 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.25972052 |
| 96 | Taste transduction_Homo sapiens_hsa04742 | 0.25462756 |
| 97 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.24517268 |
| 98 | Other glycan degradation_Homo sapiens_hsa00511 | 0.23159398 |
| 99 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.22182516 |
| 100 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.20305800 |

