SNX29P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of protein glycosylation (GO:0060049)6.07342407
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.58219593
3regulation of nuclear cell cycle DNA replication (GO:0033262)4.38616048
4G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.36679658
5peptidyl-lysine trimethylation (GO:0018023)4.31467608
6neural tube formation (GO:0001841)4.18961122
7response to pheromone (GO:0019236)3.98131459
8piRNA metabolic process (GO:0034587)3.96669867
9cell wall macromolecule catabolic process (GO:0016998)3.95697263
10axoneme assembly (GO:0035082)3.87934875
11negative regulation of mast cell activation (GO:0033004)3.84238746
12mature B cell differentiation (GO:0002335)3.79839391
13B cell receptor signaling pathway (GO:0050853)3.73106243
14fucose catabolic process (GO:0019317)3.68278804
15L-fucose metabolic process (GO:0042354)3.68278804
16L-fucose catabolic process (GO:0042355)3.68278804
17protein polyglutamylation (GO:0018095)3.67268863
18adaptation of signaling pathway (GO:0023058)3.65447537
19histone H3-K4 trimethylation (GO:0080182)3.56859507
20negative regulation of cAMP-mediated signaling (GO:0043951)3.55620974
21histone H3-K9 modification (GO:0061647)3.48141762
22epithelial cilium movement (GO:0003351)3.42048442
23DNA methylation involved in gamete generation (GO:0043046)3.39135335
24negative regulation of cytosolic calcium ion concentration (GO:0051481)3.36091193
25phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.33815875
26regulation of action potential (GO:0098900)3.31199703
27cell wall macromolecule metabolic process (GO:0044036)3.30074874
28behavioral response to nicotine (GO:0035095)3.28264810
29histone H3-K9 methylation (GO:0051567)3.25669766
30peptidyl-lysine methylation (GO:0018022)3.24583449
31pyrimidine dimer repair (GO:0006290)3.21887495
32hepatocyte apoptotic process (GO:0097284)3.20834488
33DNA deamination (GO:0045006)3.17811989
34base-excision repair, AP site formation (GO:0006285)3.17793741
35detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.15497713
36single strand break repair (GO:0000012)3.14730098
37indolalkylamine metabolic process (GO:0006586)3.14449218
38cellular biogenic amine catabolic process (GO:0042402)3.09447878
39amine catabolic process (GO:0009310)3.09447878
40negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.06612986
41negative regulation of T-helper cell differentiation (GO:0045623)3.06612986
42regulation of cilium movement (GO:0003352)3.05838466
43retinal rod cell development (GO:0046548)3.04611470
44B cell proliferation (GO:0042100)2.91739044
45photoreceptor cell maintenance (GO:0045494)2.91713942
46negative regulation of DNA-dependent DNA replication (GO:2000104)2.87981849
47positive regulation of developmental pigmentation (GO:0048087)2.86598857
48synaptic transmission, cholinergic (GO:0007271)2.84379790
49transmission of nerve impulse (GO:0019226)2.83540657
50regulation of microtubule-based movement (GO:0060632)2.81801894
51nonmotile primary cilium assembly (GO:0035058)2.81711886
52detection of light stimulus involved in sensory perception (GO:0050962)2.78657933
53detection of light stimulus involved in visual perception (GO:0050908)2.78657933
54reciprocal DNA recombination (GO:0035825)2.77641831
55reciprocal meiotic recombination (GO:0007131)2.77641831
56protein complex biogenesis (GO:0070271)2.77247656
57detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.77110874
58mitochondrial respiratory chain complex I assembly (GO:0032981)2.74279196
59NADH dehydrogenase complex assembly (GO:0010257)2.74279196
60mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.74279196
61DNA integration (GO:0015074)2.73429135
62male meiosis (GO:0007140)2.69140339
63head development (GO:0060322)2.69076141
64cilium or flagellum-dependent cell motility (GO:0001539)2.67388294
65multicellular organism reproduction (GO:0032504)2.66546180
66opioid receptor signaling pathway (GO:0038003)2.65966533
67photoreceptor cell development (GO:0042461)2.64048214
68tachykinin receptor signaling pathway (GO:0007217)2.63369874
69tryptophan metabolic process (GO:0006568)2.62902757
70intra-S DNA damage checkpoint (GO:0031573)2.59522126
71cilium movement (GO:0003341)2.58921209
72eye photoreceptor cell development (GO:0042462)2.58819453
73detection of chemical stimulus involved in sensory perception (GO:0050907)2.58681313
74regulation of telomere maintenance (GO:0032204)2.57990285
75cilium morphogenesis (GO:0060271)2.55978687
76B cell activation (GO:0042113)2.55892629
77tryptophan catabolic process (GO:0006569)2.54540189
78indole-containing compound catabolic process (GO:0042436)2.54540189
79indolalkylamine catabolic process (GO:0046218)2.54540189
80positive regulation of B cell differentiation (GO:0045579)2.53765644
81mitochondrial respiratory chain complex assembly (GO:0033108)2.52609788
82recombinational repair (GO:0000725)2.52605623
83double-strand break repair via homologous recombination (GO:0000724)2.52271713
84regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.52129536
85regulation of mitotic spindle checkpoint (GO:1903504)2.52129536
86pyrimidine nucleobase catabolic process (GO:0006208)2.50920340
87regulation of germinal center formation (GO:0002634)2.49826111
88brain morphogenesis (GO:0048854)2.49504212
89intraciliary transport (GO:0042073)2.49148176
90maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.49008752
91negative regulation of systemic arterial blood pressure (GO:0003085)2.47526449
92negative regulation of transcription regulatory region DNA binding (GO:2000678)2.46295498
93ribonucleoprotein complex disassembly (GO:0032988)2.45607200
94organelle disassembly (GO:1903008)2.45309797
95RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.45126320
96regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.43690770
97acrosome assembly (GO:0001675)2.42308369
98cornea development in camera-type eye (GO:0061303)2.41669224
99neuronal action potential (GO:0019228)2.40995065
100regulation of gene expression by genetic imprinting (GO:0006349)2.40946489

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.36033743
2ZNF274_21170338_ChIP-Seq_K562_Hela3.63527299
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.60019442
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.45068855
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.19552953
6IGF1R_20145208_ChIP-Seq_DFB_Human2.79017631
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.36948967
8VDR_22108803_ChIP-Seq_LS180_Human2.29822667
9GBX2_23144817_ChIP-Seq_PC3_Human2.22211775
10POU3F2_20337985_ChIP-ChIP_501MEL_Human2.07984807
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.04121316
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.99858556
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.97452986
14IRF1_19129219_ChIP-ChIP_H3396_Human1.96104681
15TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.92544345
16POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.92544345
17SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.76014898
18P300_19829295_ChIP-Seq_ESCs_Human1.72689239
19CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69149965
20BCAT_22108803_ChIP-Seq_LS180_Human1.67959058
21PCGF2_27294783_Chip-Seq_ESCs_Mouse1.66788073
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.64229623
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.63199630
24CBP_20019798_ChIP-Seq_JUKART_Human1.62570497
25IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.62570497
26ER_23166858_ChIP-Seq_MCF-7_Human1.59153393
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.55600762
28FUS_26573619_Chip-Seq_HEK293_Human1.55486388
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.53806150
30TCF4_23295773_ChIP-Seq_U87_Human1.53540979
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.53313233
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52913008
33TP53_22573176_ChIP-Seq_HFKS_Human1.52309571
34AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.50253088
35STAT3_23295773_ChIP-Seq_U87_Human1.49960507
36SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47881415
37IRF8_21731497_ChIP-ChIP_J774_Mouse1.46551462
38NFE2_27457419_Chip-Seq_LIVER_Mouse1.44670949
39TAF15_26573619_Chip-Seq_HEK293_Human1.40500298
40EWS_26573619_Chip-Seq_HEK293_Human1.38796423
41UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.35007310
42REST_21632747_ChIP-Seq_MESCs_Mouse1.34966088
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.32527993
44PCGF2_27294783_Chip-Seq_NPCs_Mouse1.31366784
45RNF2_27304074_Chip-Seq_NSC_Mouse1.30027458
46RBPJ_22232070_ChIP-Seq_NCS_Mouse1.29600690
47NANOG_19829295_ChIP-Seq_ESCs_Human1.25233651
48SOX2_19829295_ChIP-Seq_ESCs_Human1.25233651
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.25038002
50EGR1_23403033_ChIP-Seq_LIVER_Mouse1.24906159
51GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23643132
52SMAD4_21799915_ChIP-Seq_A2780_Human1.23576762
53NOTCH1_21737748_ChIP-Seq_TLL_Human1.23217625
54MYC_18940864_ChIP-ChIP_HL60_Human1.22671764
55PRDM14_20953172_ChIP-Seq_ESCs_Human1.21502495
56TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.21390550
57GATA3_21878914_ChIP-Seq_MCF-7_Human1.19587399
58TCF4_22108803_ChIP-Seq_LS180_Human1.18990419
59MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18317567
60CIITA_25753668_ChIP-Seq_RAJI_Human1.18300606
61CRX_20693478_ChIP-Seq_RETINA_Mouse1.18083449
62TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16180150
63EZH2_27294783_Chip-Seq_NPCs_Mouse1.14917119
64CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.14075497
65GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13241669
66BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12426781
67TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11830916
68OCT4_21477851_ChIP-Seq_ESCs_Mouse1.10672666
69GABP_17652178_ChIP-ChIP_JURKAT_Human1.10504796
70NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10444872
71STAT3_18555785_Chip-Seq_ESCs_Mouse1.10389078
72ETV2_25802403_ChIP-Seq_MESCs_Mouse1.09646885
73P53_22387025_ChIP-Seq_ESCs_Mouse1.09095947
74E2F1_18555785_Chip-Seq_ESCs_Mouse1.07622316
75VDR_23849224_ChIP-Seq_CD4+_Human1.06784045
76MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06655766
77EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06096624
78PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.05653426
79KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05421097
80FOXA1_25329375_ChIP-Seq_VCAP_Human1.04998099
81FOXA1_27270436_Chip-Seq_PROSTATE_Human1.04998099
82NANOG_18555785_Chip-Seq_ESCs_Mouse1.04832798
83AUTS2_25519132_ChIP-Seq_293T-REX_Human1.04733781
84ELK1_19687146_ChIP-ChIP_HELA_Human1.04083034
85CDX2_22108803_ChIP-Seq_LS180_Human1.03538427
86RUNX2_22187159_ChIP-Seq_PCA_Human1.03163050
87AR_25329375_ChIP-Seq_VCAP_Human1.03136150
88FLI1_21867929_ChIP-Seq_TH2_Mouse1.02580230
89OCT4_18555785_Chip-Seq_ESCs_Mouse1.02321233
90REST_18959480_ChIP-ChIP_MESCs_Mouse1.00681633
91NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.00252356
92SMRT_27268052_Chip-Seq_Bcells_Human0.99146279
93P300_18555785_Chip-Seq_ESCs_Mouse0.98571204
94CMYC_18555785_Chip-Seq_ESCs_Mouse0.98342768
95SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.97338383
96NMYC_18555785_Chip-Seq_ESCs_Mouse0.97258352
97PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97226607
98E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.96823792
99EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.96621262
100AR_20517297_ChIP-Seq_VCAP_Human0.95697228

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003787_abnormal_imprinting4.37732592
2MP0008877_abnormal_DNA_methylation4.32395438
3MP0002653_abnormal_ependyma_morphology3.25102149
4MP0003646_muscle_fatigue3.02000050
5MP0001986_abnormal_taste_sensitivity3.00444399
6MP0000372_irregular_coat_pigmentation2.86628080
7MP0000569_abnormal_digit_pigmentation2.76388675
8MP0000015_abnormal_ear_pigmentation2.47183467
9MP0002163_abnormal_gland_morphology2.42787949
10MP0000427_abnormal_hair_cycle2.37573153
11MP0006292_abnormal_olfactory_placode2.33264165
12MP0005551_abnormal_eye_electrophysiolog2.25308996
13MP0005075_abnormal_melanosome_morpholog2.23230203
14MP0005670_abnormal_white_adipose2.03034656
15MP0003121_genomic_imprinting2.02070036
16MP0001800_abnormal_humoral_immune1.82561895
17MP0005423_abnormal_somatic_nervous1.75273383
18MP0002095_abnormal_skin_pigmentation1.67982989
19MP0008057_abnormal_DNA_replication1.66135570
20MP0003122_maternal_imprinting1.64205149
21MP0003011_delayed_dark_adaptation1.59149388
22MP0008995_early_reproductive_senescence1.58040782
23MP0002876_abnormal_thyroid_physiology1.57968645
24MP0008789_abnormal_olfactory_epithelium1.50197198
25MP0005379_endocrine/exocrine_gland_phen1.47794098
26MP0005174_abnormal_tail_pigmentation1.47045510
27MP0001835_abnormal_antigen_presentation1.45540356
28MP0005645_abnormal_hypothalamus_physiol1.43540724
29MP0001968_abnormal_touch/_nociception1.43131868
30MP0009745_abnormal_behavioral_response1.41707951
31MP0000778_abnormal_nervous_system1.40575928
32MP0001790_abnormal_immune_system1.39138413
33MP0005387_immune_system_phenotype1.39138413
34MP0004142_abnormal_muscle_tone1.38936857
35MP0008872_abnormal_physiological_respon1.38787069
36MP0009046_muscle_twitch1.38609752
37MP0005394_taste/olfaction_phenotype1.34764553
38MP0005499_abnormal_olfactory_system1.34764553
39MP0001324_abnormal_eye_pigmentation1.31323469
40MP0000371_diluted_coat_color1.29512996
41MP0001984_abnormal_olfaction1.20302021
42MP0003880_abnormal_central_pattern1.18273036
43MP0003890_abnormal_embryonic-extraembry1.17451509
44MP0005646_abnormal_pituitary_gland1.16890383
45MP0002102_abnormal_ear_morphology1.16312484
46MP0002452_abnormal_antigen_presenting1.15466209
47MP0003183_abnormal_peptide_metabolism1.14037988
48MP0009764_decreased_sensitivity_to1.10859232
49MP0003879_abnormal_hair_cell1.10359760
50MP0005253_abnormal_eye_physiology1.08726926
51MP0001501_abnormal_sleep_pattern1.07449174
52MP0004043_abnormal_pH_regulation1.06681213
53MP0003786_premature_aging1.06479009
54MP0002735_abnormal_chemical_nociception1.05795295
55MP0002723_abnormal_immune_serum1.05478491
56MP0006276_abnormal_autonomic_nervous1.04918752
57MP0002572_abnormal_emotion/affect_behav1.03064948
58MP0002557_abnormal_social/conspecific_i0.99370571
59MP0005386_behavior/neurological_phenoty0.99020812
60MP0004924_abnormal_behavior0.99020812
61MP0001970_abnormal_pain_threshold0.98920498
62MP0000631_abnormal_neuroendocrine_gland0.98081637
63MP0000685_abnormal_immune_system0.98032293
64MP0002272_abnormal_nervous_system0.97604106
65MP0002733_abnormal_thermal_nociception0.97105216
66MP0004381_abnormal_hair_follicle0.96703943
67MP0003950_abnormal_plasma_membrane0.96092623
68MP0002063_abnormal_learning/memory/cond0.95878367
69MP0005310_abnormal_salivary_gland0.95832220
70MP0003195_calcinosis0.94782943
71MP0002837_dystrophic_cardiac_calcinosis0.94145913
72MP0006072_abnormal_retinal_apoptosis0.93607886
73MP0002736_abnormal_nociception_after0.92924800
74MP0008058_abnormal_DNA_repair0.91285290
75MP0004130_abnormal_muscle_cell0.90009352
76MP0000465_gastrointestinal_hemorrhage0.89103057
77MP0002420_abnormal_adaptive_immunity0.88216194
78MP0006035_abnormal_mitochondrial_morpho0.87990847
79MP0005000_abnormal_immune_tolerance0.87048570
80MP0001440_abnormal_grooming_behavior0.85753643
81MP0003698_abnormal_male_reproductive0.85363115
82MP0003763_abnormal_thymus_physiology0.83958439
83MP0003635_abnormal_synaptic_transmissio0.83729602
84MP0000689_abnormal_spleen_morphology0.83432255
85MP0001819_abnormal_immune_cell0.83416180
86MP0004147_increased_porphyrin_level0.82879669
87MP0002398_abnormal_bone_marrow0.82565405
88MP0004742_abnormal_vestibular_system0.82122119
89MP0000716_abnormal_immune_system0.80934385
90MP0002067_abnormal_sensory_capabilities0.80866390
91MP0002160_abnormal_reproductive_system0.78805795
92MP0002210_abnormal_sex_determination0.77716975
93MP0002184_abnormal_innervation0.75763712
94MP0000647_abnormal_sebaceous_gland0.74966225
95MP0009278_abnormal_bone_marrow0.74354741
96MP0005195_abnormal_posterior_eye0.72679221
97MP0005389_reproductive_system_phenotype0.72320160
98MP0002822_catalepsy0.72007394
99MP0001929_abnormal_gametogenesis0.71125408
100MP0002138_abnormal_hepatobiliary_system0.69866263

Predicted human phenotypes

RankGene SetZ-score
1Type II lissencephaly (HP:0007260)5.73370337
2Pancreatic cysts (HP:0001737)4.22476853
3Calf muscle hypertrophy (HP:0008981)3.81993935
4Retinal dysplasia (HP:0007973)3.63628103
5Pancreatic fibrosis (HP:0100732)3.58493050
6Abnormality of midbrain morphology (HP:0002418)3.56985653
7Molar tooth sign on MRI (HP:0002419)3.56985653
8Gastrointestinal stroma tumor (HP:0100723)3.56658976
9Agammaglobulinemia (HP:0004432)3.32835096
10Recurrent sinusitis (HP:0011108)3.29373337
11Lissencephaly (HP:0001339)3.27053215
12Muscle hypertrophy of the lower extremities (HP:0008968)3.26278488
13Medial flaring of the eyebrow (HP:0010747)3.17303060
14Nephronophthisis (HP:0000090)3.00774623
15Congenital stationary night blindness (HP:0007642)2.99989360
16True hermaphroditism (HP:0010459)2.94530746
17Chronic hepatic failure (HP:0100626)2.90569576
18Gait imbalance (HP:0002141)2.89497323
19Agitation (HP:0000713)2.84896944
20Abnormality of DNA repair (HP:0003254)2.84001057
21Thyroid-stimulating hormone excess (HP:0002925)2.80282792
22Pachygyria (HP:0001302)2.78667331
23Deep palmar crease (HP:0006191)2.72196872
24Cystic liver disease (HP:0006706)2.66185444
25Abnormality of the renal medulla (HP:0100957)2.59216071
26Attenuation of retinal blood vessels (HP:0007843)2.58826216
27Broad-based gait (HP:0002136)2.57700148
28Congenital primary aphakia (HP:0007707)2.56131300
29Lymphopenia (HP:0001888)2.51027006
30Aplasia/Hypoplasia of the brainstem (HP:0007362)2.50195711
31Hypoplasia of the brainstem (HP:0002365)2.50195711
32Hip dysplasia (HP:0001385)2.46214416
33Recurrent bronchitis (HP:0002837)2.45469343
34Broad alveolar ridges (HP:0000187)2.43357812
35Nephrogenic diabetes insipidus (HP:0009806)2.39393090
36Gaze-evoked nystagmus (HP:0000640)2.34011418
37Impulsivity (HP:0100710)2.30454317
38Poor coordination (HP:0002370)2.27591096
39Cerebellar dysplasia (HP:0007033)2.23957117
40Decreased central vision (HP:0007663)2.22726305
41Panhypogammaglobulinemia (HP:0003139)2.20184921
423-Methylglutaconic aciduria (HP:0003535)2.20030106
43Focal motor seizures (HP:0011153)2.15899587
44Abnormal rod and cone electroretinograms (HP:0008323)2.13211996
45Abnormality of cells of the lymphoid lineage (HP:0012140)2.11542735
46Morphological abnormality of the pyramidal tract (HP:0002062)2.07272165
47Tubular atrophy (HP:0000092)2.06217837
48Progressive inability to walk (HP:0002505)2.05926753
49Absent speech (HP:0001344)2.05902380
50Dandy-Walker malformation (HP:0001305)2.05697453
51Amelogenesis imperfecta (HP:0000705)2.05523820
52Tubulointerstitial nephritis (HP:0001970)2.05233171
53Decreased electroretinogram (ERG) amplitude (HP:0000654)2.00894039
54Chronic sinusitis (HP:0011109)1.98320293
55Vasculitis (HP:0002633)1.97946290
56Inability to walk (HP:0002540)1.94340853
57Failure to thrive in infancy (HP:0001531)1.93790605
58Recurrent pneumonia (HP:0006532)1.93040710
59Hyperventilation (HP:0002883)1.92938932
60Congenital hepatic fibrosis (HP:0002612)1.91682049
61Keratoconus (HP:0000563)1.90484480
62Increased corneal curvature (HP:0100692)1.90484480
63Abnormal hair whorl (HP:0010721)1.89180458
64Poikiloderma (HP:0001029)1.88922936
65Abnormality of the renal cortex (HP:0011035)1.88723998
66Aplasia/Hypoplasia of the tongue (HP:0010295)1.85311562
67Aplasia/Hypoplasia of the spleen (HP:0010451)1.84060855
68Papilledema (HP:0001085)1.80765050
69Hyperglycinuria (HP:0003108)1.80403878
70Oligodactyly (hands) (HP:0001180)1.79957958
71Hypoplastic iliac wings (HP:0002866)1.79066530
72Genital tract atresia (HP:0001827)1.77772312
73Volvulus (HP:0002580)1.76624672
74Asplenia (HP:0001746)1.75083914
75Bony spicule pigmentary retinopathy (HP:0007737)1.74691910
76Abnormal delayed hypersensitivity skin test (HP:0002963)1.74633741
77Vaginal atresia (HP:0000148)1.74363542
78Large eyes (HP:0001090)1.73024833
79Nephrotic syndrome (HP:0000100)1.72705224
80Polyphagia (HP:0002591)1.72135531
81Progressive cerebellar ataxia (HP:0002073)1.71501155
82Focal seizures (HP:0007359)1.71419725
83Optic nerve hypoplasia (HP:0000609)1.71370499
84Albinism (HP:0001022)1.71334669
85Hepatocellular necrosis (HP:0001404)1.69053708
86Ectropion (HP:0000656)1.69013717
87Postaxial foot polydactyly (HP:0001830)1.67398941
88Diastasis recti (HP:0001540)1.64644211
89Acute encephalopathy (HP:0006846)1.63948301
90Abnormality of the renal collecting system (HP:0004742)1.63428303
91Wide intermamillary distance (HP:0006610)1.63164959
92Meningocele (HP:0002435)1.62335750
93Polydipsia (HP:0001959)1.61459769
94Abnormal drinking behavior (HP:0030082)1.61459769
95Increased serum lactate (HP:0002151)1.61246447
96Narrow forehead (HP:0000341)1.60529826
97Retinitis pigmentosa (HP:0000510)1.60354178
98Severe visual impairment (HP:0001141)1.60156437
99Absent rod-and cone-mediated responses on ERG (HP:0007688)1.59583968
100Protruding tongue (HP:0010808)1.59331227

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K25.15179585
2CDK194.26542868
3FRK3.74262776
4CASK2.88495742
5ADRBK22.85834328
6TAOK32.33350163
7MAP3K42.30348490
8PDK22.26209826
9BLK2.24478943
10MAPK132.19905793
11TRIM281.95286579
12MARK11.86331536
13PINK11.73703211
14GRK11.72106554
15TEC1.66844901
16BMPR1B1.57672947
17SYK1.47861064
18ZAK1.45204362
19OXSR11.44225047
20DYRK31.42753386
21MAP2K71.41692887
22SIK21.31383461
23BCKDK1.31302737
24NTRK21.31241957
25MAP4K11.25587162
26WNK41.19554783
27STK391.19250355
28PRKCQ1.18192345
29PAK31.11957202
30STK31.11725759
31BTK1.09606397
32DYRK1A1.09596752
33IRAK41.02263151
34PIK3CG1.02163432
35BMPR21.01227786
36WNK30.99357586
37RPS6KA40.99177918
38ITK0.95438844
39EIF2AK30.94758277
40ERBB30.91906364
41PKN10.90724904
42ADRBK10.84686232
43PRKCZ0.83294957
44NUAK10.81386379
45JAK30.78373938
46PLK20.76745699
47BCR0.76421747
48LYN0.75365571
49ACVR1B0.74849805
50MST40.74505888
51PRKCI0.72682044
52TNK20.71261239
53MAP2K20.70284963
54MAPK110.69834928
55CAMK40.69443517
56CSF1R0.68523573
57IKBKB0.67128971
58ABL10.67017331
59RPS6KB10.66565428
60TXK0.64728237
61DYRK1B0.61623384
62ATR0.61122065
63SGK20.60493211
64RPS6KA50.59765208
65PRKCE0.59146743
66DYRK20.58000394
67NEK60.57857289
68RIPK40.57472287
69MARK20.56799704
70PNCK0.55974201
71EIF2AK20.53685868
72MARK30.52965121
73CSNK1A10.52692309
74CAMK10.52564005
75SGK10.49577238
76PRKCG0.49269368
77STK110.47343310
78TLK10.45920238
79PRKACA0.44975468
80CSNK1A1L0.44164413
81CHUK0.42856564
82CDK50.42449238
83STK380.40575448
84PRKAA10.40438058
85CSNK1D0.37882232
86CDK30.36537291
87SIK30.36511067
88BRD40.36191116
89PIM10.34835342
90CSNK2A20.34287607
91MAPK120.33890013
92PRKG10.32911675
93PRKCB0.32658536
94AKT10.32368063
95MAP2K40.32211306
96ATM0.31911008
97BRSK20.31471429
98CCNB10.31075320
99NEK20.29958637
100PDK10.29794490

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053103.41112111
2Phototransduction_Homo sapiens_hsa047443.31238094
3Basal transcription factors_Homo sapiens_hsa030223.10091455
4Intestinal immune network for IgA production_Homo sapiens_hsa046723.10071333
5Primary immunodeficiency_Homo sapiens_hsa053402.44536882
6Olfactory transduction_Homo sapiens_hsa047402.31076342
7Graft-versus-host disease_Homo sapiens_hsa053322.27585042
8Allograft rejection_Homo sapiens_hsa053302.26701576
9Regulation of autophagy_Homo sapiens_hsa041402.09535593
10Autoimmune thyroid disease_Homo sapiens_hsa053202.04528796
11B cell receptor signaling pathway_Homo sapiens_hsa046622.00842797
12Type I diabetes mellitus_Homo sapiens_hsa049401.87592444
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.87328055
14Linoleic acid metabolism_Homo sapiens_hsa005911.86347976
15Non-homologous end-joining_Homo sapiens_hsa034501.86091864
16Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.79961757
17Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.78629603
18Taste transduction_Homo sapiens_hsa047421.63179484
19Homologous recombination_Homo sapiens_hsa034401.62926443
20alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.58183824
21Systemic lupus erythematosus_Homo sapiens_hsa053221.56031125
22Fanconi anemia pathway_Homo sapiens_hsa034601.53740389
23Nitrogen metabolism_Homo sapiens_hsa009101.50091211
24Nicotine addiction_Homo sapiens_hsa050331.44812861
25Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.42376572
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38003319
27Dorso-ventral axis formation_Homo sapiens_hsa043201.34672522
28Butanoate metabolism_Homo sapiens_hsa006501.34541946
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.33652091
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.33439623
31Hematopoietic cell lineage_Homo sapiens_hsa046401.29775671
32Staphylococcus aureus infection_Homo sapiens_hsa051501.19212977
33Caffeine metabolism_Homo sapiens_hsa002321.18934946
34Ether lipid metabolism_Homo sapiens_hsa005651.13062454
35Steroid hormone biosynthesis_Homo sapiens_hsa001401.10126604
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.06817928
37ABC transporters_Homo sapiens_hsa020101.06552031
38RNA degradation_Homo sapiens_hsa030181.03471778
39Selenocompound metabolism_Homo sapiens_hsa004501.02675823
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.97895307
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.97865956
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.96483964
43Tryptophan metabolism_Homo sapiens_hsa003800.94249496
44RNA polymerase_Homo sapiens_hsa030200.93718895
45Glutamatergic synapse_Homo sapiens_hsa047240.90656854
46Viral myocarditis_Homo sapiens_hsa054160.89963180
47Carbohydrate digestion and absorption_Homo sapiens_hsa049730.89906429
48Glycerolipid metabolism_Homo sapiens_hsa005610.89657521
49Alcoholism_Homo sapiens_hsa050340.88258885
50Antigen processing and presentation_Homo sapiens_hsa046120.87424931
51Arachidonic acid metabolism_Homo sapiens_hsa005900.83743893
52Morphine addiction_Homo sapiens_hsa050320.83702435
53Propanoate metabolism_Homo sapiens_hsa006400.83617991
54Primary bile acid biosynthesis_Homo sapiens_hsa001200.82821473
55Pentose phosphate pathway_Homo sapiens_hsa000300.82317668
56Tuberculosis_Homo sapiens_hsa051520.81078892
57Oxidative phosphorylation_Homo sapiens_hsa001900.76765846
58Parkinsons disease_Homo sapiens_hsa050120.76575636
59Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68115372
60Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.66097730
61Serotonergic synapse_Homo sapiens_hsa047260.65237278
62Salivary secretion_Homo sapiens_hsa049700.64766615
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64722260
64Rheumatoid arthritis_Homo sapiens_hsa053230.63351520
65Leishmaniasis_Homo sapiens_hsa051400.59269883
66Huntingtons disease_Homo sapiens_hsa050160.58850190
67Ovarian steroidogenesis_Homo sapiens_hsa049130.57389348
68Peroxisome_Homo sapiens_hsa041460.56749969
69SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55995829
70Calcium signaling pathway_Homo sapiens_hsa040200.55822538
71Cardiac muscle contraction_Homo sapiens_hsa042600.54151622
72Nucleotide excision repair_Homo sapiens_hsa034200.53034152
73Chemical carcinogenesis_Homo sapiens_hsa052040.52633388
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.52513905
75Herpes simplex infection_Homo sapiens_hsa051680.52015269
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50401130
77Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.49828317
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.48115401
79Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47599647
80GABAergic synapse_Homo sapiens_hsa047270.46037234
81mRNA surveillance pathway_Homo sapiens_hsa030150.44985560
82Platelet activation_Homo sapiens_hsa046110.44083246
83Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42200008
84Oxytocin signaling pathway_Homo sapiens_hsa049210.40017127
85Retinol metabolism_Homo sapiens_hsa008300.39841230
86Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.38769549
87Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36956954
88Dopaminergic synapse_Homo sapiens_hsa047280.36889270
89T cell receptor signaling pathway_Homo sapiens_hsa046600.35626808
90Lysine degradation_Homo sapiens_hsa003100.32458307
91Long-term depression_Homo sapiens_hsa047300.32039137
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.30791274
93Jak-STAT signaling pathway_Homo sapiens_hsa046300.30392466
94Type II diabetes mellitus_Homo sapiens_hsa049300.29495651
95Notch signaling pathway_Homo sapiens_hsa043300.29363437
96Collecting duct acid secretion_Homo sapiens_hsa049660.29089046
97Epstein-Barr virus infection_Homo sapiens_hsa051690.29004597
98Alzheimers disease_Homo sapiens_hsa050100.28751644
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.28372674
100Protein export_Homo sapiens_hsa030600.28346924

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