SOGA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)4.66031548
2layer formation in cerebral cortex (GO:0021819)3.68306426
3establishment of nucleus localization (GO:0040023)3.54686885
4cellular potassium ion homeostasis (GO:0030007)3.48307387
5glutamate secretion (GO:0014047)3.45209943
6postsynaptic membrane organization (GO:0001941)3.38402157
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.31675157
8cytoskeletal anchoring at plasma membrane (GO:0007016)3.19574668
9dendrite morphogenesis (GO:0048813)3.18944197
10vocalization behavior (GO:0071625)3.12849748
11semaphorin-plexin signaling pathway (GO:0071526)3.12576164
12locomotory exploration behavior (GO:0035641)3.11554045
13regulation of ARF GTPase activity (GO:0032312)3.07042919
14cell migration in hindbrain (GO:0021535)3.04501787
15planar cell polarity pathway involved in neural tube closure (GO:0090179)3.03627838
16negative regulation of granulocyte differentiation (GO:0030853)3.02092125
17cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.01600122
18ionotropic glutamate receptor signaling pathway (GO:0035235)2.95381188
19cell-cell junction maintenance (GO:0045217)2.93700234
20neuron recognition (GO:0008038)2.92364164
21myelination in peripheral nervous system (GO:0022011)2.91713258
22peripheral nervous system axon ensheathment (GO:0032292)2.91713258
23microglial cell activation (GO:0001774)2.90468737
24regulation of synaptic vesicle exocytosis (GO:2000300)2.88911682
25synaptic vesicle exocytosis (GO:0016079)2.88233846
26synaptic vesicle maturation (GO:0016188)2.86353666
27cerebellar granule cell differentiation (GO:0021707)2.83441717
28regulation of neuronal synaptic plasticity (GO:0048168)2.82684143
29germ cell migration (GO:0008354)2.81576345
30regulation of synapse maturation (GO:0090128)2.81485288
31regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.81078208
32apical protein localization (GO:0045176)2.79552883
33positive regulation of chemokine secretion (GO:0090197)2.78561889
34cortical actin cytoskeleton organization (GO:0030866)2.76923711
35neuron cell-cell adhesion (GO:0007158)2.76232513
36insulin-like growth factor receptor signaling pathway (GO:0048009)2.74471148
37cell junction maintenance (GO:0034331)2.72969350
38cerebellar Purkinje cell layer development (GO:0021680)2.71639333
39cerebellar Purkinje cell differentiation (GO:0021702)2.70196134
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.69241318
41regulation of neuron migration (GO:2001222)2.68924368
42neuronal ion channel clustering (GO:0045161)2.68740036
43plasma membrane repair (GO:0001778)2.68181274
44neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.67302915
45protein localization to synapse (GO:0035418)2.65970147
46neurotransmitter secretion (GO:0007269)2.60827641
47stress fiber assembly (GO:0043149)2.59600645
48sodium ion export (GO:0071436)2.59462576
49axonal fasciculation (GO:0007413)2.59446488
50negative regulation of catenin import into nucleus (GO:0035414)2.58082465
51regulation of NFAT protein import into nucleus (GO:0051532)2.57839546
52neurotransmitter-gated ion channel clustering (GO:0072578)2.56691832
53regulation of ARF protein signal transduction (GO:0032012)2.56669572
54regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.56659454
55apoptotic cell clearance (GO:0043277)2.55803343
56dendritic spine morphogenesis (GO:0060997)2.55348925
57clathrin coat assembly (GO:0048268)2.54694996
58neuromuscular process controlling balance (GO:0050885)2.54575815
59regulation of glutamate receptor signaling pathway (GO:1900449)2.54502025
60positive regulation of synapse maturation (GO:0090129)2.54404697
61nucleus localization (GO:0051647)2.54238580
62adherens junction assembly (GO:0034333)2.53515169
63positive regulation of axon extension (GO:0045773)2.52904098
64auditory behavior (GO:0031223)2.52867744
65nerve growth factor signaling pathway (GO:0038180)2.51191707
66macrophage activation involved in immune response (GO:0002281)2.50539623
67amino acid import (GO:0043090)2.50038656
68regulation of synapse structural plasticity (GO:0051823)2.49481715
69regulation of long-term neuronal synaptic plasticity (GO:0048169)2.49476544
70exploration behavior (GO:0035640)2.47661966
71endothelial cell chemotaxis (GO:0035767)2.46970126
72embryonic retina morphogenesis in camera-type eye (GO:0060059)2.46891374
73chondroitin sulfate catabolic process (GO:0030207)2.46417342
74presynaptic membrane assembly (GO:0097105)2.45988929
75cytoplasmic mRNA processing body assembly (GO:0033962)2.45915969
76neural tube development (GO:0021915)2.45247951
77central nervous system projection neuron axonogenesis (GO:0021952)2.43540958
78regulation of synaptic vesicle transport (GO:1902803)2.42500722
79synaptic vesicle endocytosis (GO:0048488)2.41249391
80regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.38375970
81cortical cytoskeleton organization (GO:0030865)2.37416955
82peptidyl-lysine dimethylation (GO:0018027)2.36670079
83negative regulation of translation, ncRNA-mediated (GO:0040033)2.35848722
84regulation of translation, ncRNA-mediated (GO:0045974)2.35848722
85negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.35848722
86presynaptic membrane organization (GO:0097090)2.35109628
87spinal cord development (GO:0021510)2.34890756
88cell communication involved in cardiac conduction (GO:0086065)2.34249032
89negative regulation of dendrite morphogenesis (GO:0050774)2.33619839
90cell differentiation in hindbrain (GO:0021533)2.33604152
91axon extension (GO:0048675)2.33098278
92potassium ion homeostasis (GO:0055075)2.32948767
93Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.32635734
94heart morphogenesis (GO:0003007)2.32614722
95I-kappaB phosphorylation (GO:0007252)2.32331121
96cell adhesion mediated by integrin (GO:0033627)2.32297251
97positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.31832236
98positive regulation of dendrite development (GO:1900006)2.31494945
99dendritic spine organization (GO:0097061)2.30909087
100glutamate receptor signaling pathway (GO:0007215)2.30051919
101synaptic transmission, glutamatergic (GO:0035249)2.29458401
102stress granule assembly (GO:0034063)2.29387323
103glucocorticoid receptor signaling pathway (GO:0042921)2.27626440
104focal adhesion assembly (GO:0048041)2.27078132
105cell-substrate adherens junction assembly (GO:0007045)2.27078132
106positive regulation of synapse assembly (GO:0051965)2.26815437
107gastrulation with mouth forming second (GO:0001702)2.26262882
108protein retention in ER lumen (GO:0006621)2.26227518
109G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.26157210
110positive regulation of dendritic spine development (GO:0060999)2.25615333
111dopamine receptor signaling pathway (GO:0007212)2.25348992
112outer ear morphogenesis (GO:0042473)2.24789974
113cellular response to catecholamine stimulus (GO:0071870)2.24555723
114cellular response to monoamine stimulus (GO:0071868)2.24555723
115cellular sodium ion homeostasis (GO:0006883)2.23678854
116negative regulation of vascular permeability (GO:0043116)2.23318770
117response to fluid shear stress (GO:0034405)2.22972257
118L-amino acid import (GO:0043092)2.22963877
119neuron projection extension involved in neuron projection guidance (GO:1902284)2.22451782
120axon extension involved in axon guidance (GO:0048846)2.22451782
121cell communication by electrical coupling (GO:0010644)2.22435149
122regulation of establishment of planar polarity (GO:0090175)2.21996486
123positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.21996153
124membrane assembly (GO:0071709)2.21901206
125synapse assembly (GO:0007416)2.21552119
126establishment of spindle localization (GO:0051293)2.20917803
127positive regulation of dendritic spine morphogenesis (GO:0061003)2.20552411
128modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.20320499
129positive regulation by organism of defense response of other organism involved in symbiotic interact2.20320499
130modulation by symbiont of host immune response (GO:0052553)2.20320499
131positive regulation by symbiont of host defense response (GO:0052509)2.20320499
132modulation by symbiont of host defense response (GO:0052031)2.20320499
133modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.20320499
134negative regulation of cell size (GO:0045792)2.20131783
135mating behavior (GO:0007617)2.19358220
136hippo signaling (GO:0035329)2.18984340
137positive regulation of SMAD protein import into nucleus (GO:0060391)2.18586674
138embryonic viscerocranium morphogenesis (GO:0048703)2.16883732
139cellular response to fluid shear stress (GO:0071498)2.16798753
140response to pheromone (GO:0019236)2.16252156
141regulation of axon extension involved in axon guidance (GO:0048841)2.14585803
142monocyte differentiation (GO:0030224)2.14532378
143neuroblast proliferation (GO:0007405)2.13751016
144positive regulation of fibroblast migration (GO:0010763)2.13715954
145substrate-dependent cell migration (GO:0006929)2.11785305
146NLS-bearing protein import into nucleus (GO:0006607)2.11723440
147negative regulation of smooth muscle cell migration (GO:0014912)2.11664320
148cardiac myofibril assembly (GO:0055003)2.11003122
149positive regulation of axonogenesis (GO:0050772)2.08762818
150negative regulation of fatty acid transport (GO:2000192)2.07551589
151mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.06671841
152lamellipodium assembly (GO:0030032)2.06518875
153lamellipodium organization (GO:0097581)2.06447588
154receptor catabolic process (GO:0032801)2.05146856
155camera-type eye morphogenesis (GO:0048593)2.05052144
156regulation of axon guidance (GO:1902667)2.04571680
157positive regulation of glycogen biosynthetic process (GO:0045725)2.04366092
158macroautophagy (GO:0016236)2.04124206
159regulation of short-term neuronal synaptic plasticity (GO:0048172)2.03891525
160neuron projection extension (GO:1990138)2.03345596
161regulation of axon extension (GO:0030516)2.03261516
162positive regulation of histone deacetylation (GO:0031065)2.01829721
163positive regulation of dendrite morphogenesis (GO:0050775)2.01660470
164regulation of SMAD protein import into nucleus (GO:0060390)2.01522007
165filopodium assembly (GO:0046847)2.01119599
166activation of protein kinase A activity (GO:0034199)2.01067170

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.91272934
2EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.68431655
3EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.58167997
4EGR1_19374776_ChIP-ChIP_THP-1_Human2.56795043
5DROSHA_22980978_ChIP-Seq_HELA_Human2.43413596
6KDM2B_26808549_Chip-Seq_SUP-B15_Human2.37273243
7WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.26629468
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.25649562
9KDM2B_26808549_Chip-Seq_K562_Human2.22317619
10STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.19109539
11EZH2_22144423_ChIP-Seq_EOC_Human2.14203406
12KDM2B_26808549_Chip-Seq_DND41_Human2.13851687
13DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.04171105
14TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.01877159
15ZFP281_18757296_ChIP-ChIP_E14_Mouse1.97914968
16TCF7_22412390_ChIP-Seq_EML_Mouse1.94259040
17ZFP281_27345836_Chip-Seq_ESCs_Mouse1.93557203
18SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.88206052
19STAT6_21828071_ChIP-Seq_BEAS2B_Human1.80703190
20VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.79566740
21KDM2B_26808549_Chip-Seq_JURKAT_Human1.78401587
22EZH2_18974828_ChIP-Seq_MESCs_Mouse1.75996174
23RNF2_18974828_ChIP-Seq_MESCs_Mouse1.75996174
24SCL_19346495_ChIP-Seq_HPC-7_Human1.73771695
25KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.72122103
26NFIB_24661679_ChIP-Seq_LUNG_Mouse1.67977799
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.64507183
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.64383497
29KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.62349029
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.59968828
31RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.57623035
32SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.57004002
33JARID2_20064375_ChIP-Seq_MESCs_Mouse1.54790453
34ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.53791568
35WT1_25993318_ChIP-Seq_PODOCYTE_Human1.53612834
36RNF2_27304074_Chip-Seq_ESCs_Mouse1.51624327
37THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.50272269
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.50092740
39MTF2_20144788_ChIP-Seq_MESCs_Mouse1.48472606
40SPI1_23127762_ChIP-Seq_K562_Human1.48237712
41AR_21572438_ChIP-Seq_LNCaP_Human1.47284053
42P300_27058665_Chip-Seq_ZR-75-30cells_Human1.46737291
43SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.46538382
44EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.43919173
45MYC_22102868_ChIP-Seq_BL_Human1.43664953
46LXR_22292898_ChIP-Seq_THP-1_Human1.42971771
47SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.41812314
48EZH2_27304074_Chip-Seq_ESCs_Mouse1.39146067
49SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.38857282
50RARB_27405468_Chip-Seq_BRAIN_Mouse1.38723012
51CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.37976475
52SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.37271155
53TP53_20018659_ChIP-ChIP_R1E_Mouse1.37213672
54SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.35975729
55EZH2_27294783_Chip-Seq_ESCs_Mouse1.35622454
56JARID2_20075857_ChIP-Seq_MESCs_Mouse1.34897135
57OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.34402809
58RING1B_27294783_Chip-Seq_NPCs_Mouse1.33784023
59SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.32271447
60ESR2_21235772_ChIP-Seq_MCF-7_Human1.32212381
61RARG_19884340_ChIP-ChIP_MEFs_Mouse1.30898127
62ZNF217_24962896_ChIP-Seq_MCF-7_Human1.29180471
63SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.28848183
64TP53_16413492_ChIP-PET_HCT116_Human1.28663983
65ISL1_27105846_Chip-Seq_CPCs_Mouse1.27518167
66HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.26700415
67EED_16625203_ChIP-ChIP_MESCs_Mouse1.25956969
68RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.25812828
69ESR1_21235772_ChIP-Seq_MCF-7_Human1.25014365
70GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24921859
71VDR_21846776_ChIP-Seq_THP-1_Human1.24849045
72SOX9_24532713_ChIP-Seq_HFSC_Mouse1.24747000
73ESR1_20079471_ChIP-ChIP_T-47D_Human1.24527836
74REST_18959480_ChIP-ChIP_MESCs_Mouse1.23268905
75DNAJC2_21179169_ChIP-ChIP_NT2_Human1.23233144
76IKZF1_21737484_ChIP-ChIP_HCT116_Human1.22545784
77SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22194014
78YAP1_20516196_ChIP-Seq_MESCs_Mouse1.21417436
79TP63_17297297_ChIP-ChIP_HaCaT_Human1.21374907
80WT1_19549856_ChIP-ChIP_CCG9911_Human1.19494088
81RACK7_27058665_Chip-Seq_MCF-7_Human1.19052723
82ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.18037473
83FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.16165628
84CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.15491135
85CBX2_27304074_Chip-Seq_ESCs_Mouse1.15213472
86TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.14063480
87ZNF274_21170338_ChIP-Seq_K562_Hela1.14003885
88CTNNB1_20460455_ChIP-Seq_HCT116_Human1.12923372
89TET1_21490601_ChIP-Seq_MESCs_Mouse1.12173413
90STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.10411503
91ESR1_15608294_ChIP-ChIP_MCF-7_Human1.09647108
92RING1B_27294783_Chip-Seq_ESCs_Mouse1.08579021
93GBX2_23144817_ChIP-Seq_PC3_Human1.08305895
94RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.07551244
95EP300_21415370_ChIP-Seq_HL-1_Mouse1.07507436
96FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.06993403
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06513517
98NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.05402850
99PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.05095083
100PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.04574983
101GATA1_19941826_ChIP-Seq_K562_Human1.04552052
102CTCF_27219007_Chip-Seq_Bcells_Human1.04013925
103RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03781573
104RUNX1_27514584_Chip-Seq_MCF-7_Human1.02563803
105UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.01403993
106SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.01399774
107TBX20_22080862_ChIP-Seq_HEART_Mouse1.00716316
108TBX20_22328084_ChIP-Seq_HEART_Mouse1.00716316
109AHR_22903824_ChIP-Seq_MCF-7_Human1.00054425
110ERG_21242973_ChIP-ChIP_JURKAT_Human0.99499374
111SMC4_20622854_ChIP-Seq_HELA_Human0.99194918
112TRIM28_21343339_ChIP-Seq_HEK293_Human0.98672510
113CLOCK_20551151_ChIP-Seq_293T_Human0.97583035
114FOXM1_23109430_ChIP-Seq_U2OS_Human0.97521341
115CREB1_26743006_Chip-Seq_LNCaP_Human0.97482760
116AR_19668381_ChIP-Seq_PC3_Human0.97091411
117ARNT_22903824_ChIP-Seq_MCF-7_Human0.96475009
118REST_21632747_ChIP-Seq_MESCs_Mouse0.96328572
119PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95758679
120KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.95737548
121VDR_24763502_ChIP-Seq_THP-1_Human0.95352181
122CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.94870968
123TP53_23651856_ChIP-Seq_MEFs_Mouse0.94013932
124NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.92766095
125ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.92099509
126SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.92072970
127TP53_22127205_ChIP-Seq_IMR90_Human0.91526913
128GATA1_26923725_Chip-Seq_HPCs_Mouse0.85722112
129POU5F1_16518401_ChIP-PET_MESCs_Mouse0.84740242

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.75067882
2MP0003705_abnormal_hypodermis_morpholog2.90070012
3MP0004859_abnormal_synaptic_plasticity2.82805065
4MP0005409_darkened_coat_color2.59759218
5MP0008438_abnormal_cutaneous_collagen2.57789608
6MP0005076_abnormal_cell_differentiation2.38643266
7MP0009278_abnormal_bone_marrow2.30801591
8MP0003172_abnormal_lysosome_physiology2.25850077
9MP0003283_abnormal_digestive_organ2.21375797
10MP0005623_abnormal_meninges_morphology2.07743347
11MP0001299_abnormal_eye_distance/1.98068561
12MP0003279_aneurysm1.85586613
13MP0002734_abnormal_mechanical_nocicepti1.84709393
14MP0004858_abnormal_nervous_system1.82969937
15MP0003303_peritoneal_inflammation1.81010333
16MP0000733_abnormal_muscle_development1.79622366
17MP0003045_fibrosis1.76410933
18MP0000778_abnormal_nervous_system1.71455149
19MP0005257_abnormal_intraocular_pressure1.65015435
20MP0003566_abnormal_cell_adhesion1.61007331
21MP0002249_abnormal_larynx_morphology1.57957347
22MP0009780_abnormal_chondrocyte_physiolo1.56420872
23MP0003091_abnormal_cell_migration1.55663654
24MP0002572_abnormal_emotion/affect_behav1.53938148
25MP0008961_abnormal_basal_metabolism1.53341936
26MP0003880_abnormal_central_pattern1.52788226
27MP0002735_abnormal_chemical_nociception1.51634003
28MP0004145_abnormal_muscle_electrophysio1.47762325
29MP0003300_gastrointestinal_ulcer1.44075304
30MP0003329_amyloid_beta_deposits1.42372234
31MP0001486_abnormal_startle_reflex1.40813555
32MP0000579_abnormal_nail_morphology1.40439320
33MP0002653_abnormal_ependyma_morphology1.38590185
34MP0003122_maternal_imprinting1.38074440
35MP0009745_abnormal_behavioral_response1.37638167
36MP0003879_abnormal_hair_cell1.37485298
37MP0003385_abnormal_body_wall1.36312555
38MP0003635_abnormal_synaptic_transmissio1.33994393
39MP0010352_gastrointestinal_tract_polyps1.33262642
40MP0002272_abnormal_nervous_system1.33128919
41MP0005171_absent_coat_pigmentation1.33017578
42MP0004510_myositis1.33011773
43MP0001849_ear_inflammation1.29201319
44MP0000534_abnormal_ureter_morphology1.27824800
45MP0000566_synostosis1.27344906
46MP0000767_abnormal_smooth_muscle1.26122722
47MP0010368_abnormal_lymphatic_system1.23941379
48MP0003123_paternal_imprinting1.23445791
49MP0005187_abnormal_penis_morphology1.23268145
50MP0005670_abnormal_white_adipose1.22980814
51MP0001958_emphysema1.22666503
52MP0004185_abnormal_adipocyte_glucose1.20127988
53MP0004270_analgesia1.20010640
54MP0004272_abnormal_basement_membrane1.19887737
55MP0002822_catalepsy1.18680961
56MP0004811_abnormal_neuron_physiology1.17416742
57MP0003690_abnormal_glial_cell1.17295513
58MP0008569_lethality_at_weaning1.15792563
59MP0002896_abnormal_bone_mineralization1.15518162
60MP0001502_abnormal_circadian_rhythm1.15359510
61MP0004084_abnormal_cardiac_muscle1.13600072
62MP0000537_abnormal_urethra_morphology1.13344466
63MP0000955_abnormal_spinal_cord1.13238479
64MP0004885_abnormal_endolymph1.12710312
65MP0001915_intracranial_hemorrhage1.11448464
66MP0005058_abnormal_lysosome_morphology1.10343127
67MP0003115_abnormal_respiratory_system1.09474916
68MP0002925_abnormal_cardiovascular_devel1.09023029
69MP0003634_abnormal_glial_cell1.08936603
70MP0002089_abnormal_postnatal_growth/wei1.06749902
71MP0001968_abnormal_touch/_nociception1.06618538
72MP0009046_muscle_twitch1.05533376
73MP0002234_abnormal_pharynx_morphology1.05377135
74MP0005275_abnormal_skin_tensile1.03417343
75MP0004130_abnormal_muscle_cell1.03165010
76MP0000751_myopathy1.02743960
77MP0003861_abnormal_nervous_system1.02462997
78MP0001177_atelectasis1.02453027
79MP0001440_abnormal_grooming_behavior1.01862234
80MP0001348_abnormal_lacrimal_gland1.01768679
81MP0001970_abnormal_pain_threshold1.01625486
82MP0005666_abnormal_adipose_tissue1.01419408
83MP0004233_abnormal_muscle_weight1.01297265
84MP0002909_abnormal_adrenal_gland1.00677008
85MP0002152_abnormal_brain_morphology1.00288349
86MP0000428_abnormal_craniofacial_morphol1.00165260
87MP0002184_abnormal_innervation0.99300498
88MP0005503_abnormal_tendon_morphology0.99055233
89MP0005375_adipose_tissue_phenotype0.98299530
90MP0005423_abnormal_somatic_nervous0.97901790
91MP0002733_abnormal_thermal_nociception0.97177888
92MP0010030_abnormal_orbit_morphology0.97112201
93MP0003183_abnormal_peptide_metabolism0.96943691
94MP0005167_abnormal_blood-brain_barrier0.96561235
95MP0002928_abnormal_bile_duct0.96013379
96MP0009053_abnormal_anal_canal0.95826255
97MP0010630_abnormal_cardiac_muscle0.95764412
98MP0003935_abnormal_craniofacial_develop0.95645753
99MP0000462_abnormal_digestive_system0.94599731
100MP0003632_abnormal_nervous_system0.93369722
101MP0004087_abnormal_muscle_fiber0.92008701
102MP0002116_abnormal_craniofacial_bone0.91344084
103MP0002066_abnormal_motor_capabilities/c0.91289790
104MP0000003_abnormal_adipose_tissue0.90634025
105MP0002877_abnormal_melanocyte_morpholog0.87045166
106MP0004808_abnormal_hematopoietic_stem0.86998671
107MP0002998_abnormal_bone_remodeling0.85690368
108MP0000747_muscle_weakness0.85088449
109MP0009384_cardiac_valve_regurgitation0.84315841
110MP0002063_abnormal_learning/memory/cond0.83935602
111MP0005386_behavior/neurological_phenoty0.83739781
112MP0004924_abnormal_behavior0.83739781
113MP0003787_abnormal_imprinting0.83255598
114MP0002092_abnormal_eye_morphology0.82343101
115MP0002557_abnormal_social/conspecific_i0.82028279
116MP0009250_abnormal_appendicular_skeleto0.81906209
117MP0002064_seizures0.81580928
118MP0003075_altered_response_to0.80965660
119MP0001501_abnormal_sleep_pattern0.79973235
120MP0005508_abnormal_skeleton_morphology0.79516373
121MP0000432_abnormal_head_morphology0.79248804
122MP0000920_abnormal_myelination0.79097292
123MP0000266_abnormal_heart_morphology0.78725283
124MP0001614_abnormal_blood_vessel0.78266532
125MP0002128_abnormal_blood_circulation0.78174321
126MP0000762_abnormal_tongue_morphology0.78165333
127MP0001346_abnormal_lacrimal_gland0.78053870
128MP0002697_abnormal_eye_size0.77212373
129MP0003121_genomic_imprinting0.77170482
130MP0002108_abnormal_muscle_morphology0.76341945
131MP0009672_abnormal_birth_weight0.75695975
132MP0002882_abnormal_neuron_morphology0.75424626
133MP0001851_eye_inflammation0.74480740
134MP0002114_abnormal_axial_skeleton0.73769291
135MP0002067_abnormal_sensory_capabilities0.73685717
136MP0002081_perinatal_lethality0.73437520
137MP0003755_abnormal_palate_morphology0.73291605
138MP0003942_abnormal_urinary_system0.72686736
139MP0004134_abnormal_chest_morphology0.72485369
140MP0006276_abnormal_autonomic_nervous0.72257335
141MP0001984_abnormal_olfaction0.72010434
142MP0003631_nervous_system_phenotype0.70610653
143MP0001943_abnormal_respiration0.70249387

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)4.62835267
2Shallow orbits (HP:0000586)4.15922939
3Hyperacusis (HP:0010780)3.63765711
4Arterial tortuosity (HP:0005116)3.14201267
5Short 4th metacarpal (HP:0010044)3.02341659
6Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.02341659
7Elfin facies (HP:0004428)3.02243454
8Mutism (HP:0002300)2.94214777
9Vascular tortuosity (HP:0004948)2.83760021
10Aortic aneurysm (HP:0004942)2.81335639
11Bladder diverticulum (HP:0000015)2.76516863
12Renovascular hypertension (HP:0100817)2.73192775
13Urethral obstruction (HP:0000796)2.71390078
14Renal duplication (HP:0000075)2.70605630
15Overriding aorta (HP:0002623)2.68453083
16Macroorchidism (HP:0000053)2.64083482
17Insomnia (HP:0100785)2.63268797
18Systemic lupus erythematosus (HP:0002725)2.61219474
19Bowel diverticulosis (HP:0005222)2.57806370
20Broad face (HP:0000283)2.57046245
21Flat cornea (HP:0007720)2.56604898
22Mitral valve prolapse (HP:0001634)2.51675953
23Arnold-Chiari malformation (HP:0002308)2.50400117
24Myokymia (HP:0002411)2.45227837
25Bronchomalacia (HP:0002780)2.44791289
26Protrusio acetabuli (HP:0003179)2.43335943
27Disproportionate tall stature (HP:0001519)2.40455123
28Aortic dissection (HP:0002647)2.39835318
29Focal seizures (HP:0007359)2.39321133
30Striae distensae (HP:0001065)2.37568309
31Hematochezia (HP:0002573)2.36335603
32Broad metatarsal (HP:0001783)2.32709563
33Hand muscle atrophy (HP:0009130)2.31812562
34Focal motor seizures (HP:0011153)2.31056261
35Pointed chin (HP:0000307)2.29156591
36Distal upper limb amyotrophy (HP:0007149)2.28313616
37Upper limb amyotrophy (HP:0009129)2.28313616
38Action tremor (HP:0002345)2.27769031
39Dysmetric saccades (HP:0000641)2.27409993
40Neurofibrillary tangles (HP:0002185)2.27389593
41Abnormality of the 4th metacarpal (HP:0010012)2.25554920
42Vertebral arch anomaly (HP:0008438)2.24891451
43Abnormality of liposaccharide metabolism (HP:0010968)2.23904572
44Abnormality of glycosphingolipid metabolism (HP:0004343)2.23904572
45Abnormality of glycolipid metabolism (HP:0010969)2.23904572
46Aqueductal stenosis (HP:0002410)2.23694243
47Ulnar bowing (HP:0003031)2.19734171
48Disinhibition (HP:0000734)2.16960800
49Cerebral inclusion bodies (HP:0100314)2.13518522
50Glomerulonephritis (HP:0000099)2.11683845
51Hemiplegia (HP:0002301)2.10232911
52Aneurysm (HP:0002617)2.06371806
53Dilatation of the ascending aorta (HP:0005111)2.05214206
54Abnormality of the distal phalanx of the thumb (HP:0009617)2.04384253
55Narrow palate (HP:0000189)2.04220369
56Premature rupture of membranes (HP:0001788)2.03925767
57Obstructive sleep apnea (HP:0002870)2.03774698
58Hypoventilation (HP:0002791)2.02657411
59Neuronal loss in central nervous system (HP:0002529)2.02441592
60Increased cerebral lipofuscin (HP:0011813)2.00619553
61Precocious puberty (HP:0000826)2.00604596
62Progressive cerebellar ataxia (HP:0002073)2.00268789
63Genetic anticipation (HP:0003743)1.99094041
64Deviation of the hallux (HP:0010051)1.95033690
65Enlarged penis (HP:0000040)1.94916296
66Hallux valgus (HP:0001822)1.94188359
67Neonatal short-limb short stature (HP:0008921)1.90659993
68Inappropriate behavior (HP:0000719)1.89868178
69Scapular winging (HP:0003691)1.89288896
70Genu recurvatum (HP:0002816)1.89119665
71Broad ribs (HP:0000885)1.88607726
72Obsessive-compulsive behavior (HP:0000722)1.86569339
73Supranuclear gaze palsy (HP:0000605)1.86172749
74Epileptic encephalopathy (HP:0200134)1.85858531
75Diplopia (HP:0000651)1.85553254
76Abnormality of binocular vision (HP:0011514)1.85553254
77Wide anterior fontanel (HP:0000260)1.85085547
78Truncal ataxia (HP:0002078)1.84730924
79Apathy (HP:0000741)1.84000857
80Neoplasm of the heart (HP:0100544)1.83732678
81Patellar dislocation (HP:0002999)1.82383771
82Trigonocephaly (HP:0000243)1.81612230
83Sparse lateral eyebrow (HP:0005338)1.79489261
84Aplasia involving bones of the extremities (HP:0009825)1.79446866
85Aplasia involving bones of the upper limbs (HP:0009823)1.79446866
86Aplasia of the phalanges of the hand (HP:0009802)1.79446866
87Sleep apnea (HP:0010535)1.78742778
88Turricephaly (HP:0000262)1.78661789
89Abnormality of the fingertips (HP:0001211)1.78065109
90Morphological abnormality of the middle ear (HP:0008609)1.77929252
91Advanced eruption of teeth (HP:0006288)1.76884469
92Atrophic scars (HP:0001075)1.75989229
93Tracheomalacia (HP:0002779)1.75606238
94Urinary bladder sphincter dysfunction (HP:0002839)1.74307846
95Annular pancreas (HP:0001734)1.74158763
96Heterotopia (HP:0002282)1.73555564
97Mitral regurgitation (HP:0001653)1.71988297
98Laryngomalacia (HP:0001601)1.71719293
99Spondylolisthesis (HP:0003302)1.71111111
100Abnormality of the diencephalon (HP:0010662)1.69868813
101Hammertoe (HP:0001765)1.69414537
102Fragile skin (HP:0001030)1.69361372
103Impaired smooth pursuit (HP:0007772)1.68892733
104Increased nuchal translucency (HP:0010880)1.68802838
105Germ cell neoplasia (HP:0100728)1.68532720
106Intestinal atresia (HP:0011100)1.68187451
107Abnormality of the phalanges of the hallux (HP:0010057)1.67313931
108Buphthalmos (HP:0000557)1.67211152
109Megalocornea (HP:0000485)1.66489728
110Difficulty running (HP:0009046)1.66448932
111Shawl scrotum (HP:0000049)1.65639471
112Broad thumb (HP:0011304)1.65257811
113Lymphangioma (HP:0100764)1.65191486
114Retinal atrophy (HP:0001105)1.64092312
115Asymmetry of the thorax (HP:0001555)1.63557452
116Wormian bones (HP:0002645)1.63303185
117Subacute progressive viral hepatitis (HP:0006572)1.63142456
118Sacral dimple (HP:0000960)1.63016589
119Lower limb asymmetry (HP:0100559)1.62521054
120Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.62463952
121Increased density of long bones (HP:0006392)1.61635512
122Overgrowth (HP:0001548)1.60332036
123Ankle contracture (HP:0006466)1.59803026
124Joint laxity (HP:0001388)1.59128957
125Diminished motivation (HP:0000745)1.58254476
126Relative macrocephaly (HP:0004482)1.58064417
127Postural instability (HP:0002172)1.58018133
128Absent frontal sinuses (HP:0002688)1.57367291
129Abnormality of the ischium (HP:0003174)1.57046853
130Natal tooth (HP:0000695)1.56542742
131Soft skin (HP:0000977)1.55128367
132Mild short stature (HP:0003502)1.54648173
133Febrile seizures (HP:0002373)1.54154052
134Leiomyosarcoma (HP:0100243)1.53552994
135Uterine leiomyosarcoma (HP:0002891)1.53552994
136Long palpebral fissure (HP:0000637)1.52388104
137Thick eyebrow (HP:0000574)1.51399969
138Hyperextensible skin (HP:0000974)1.51303568
139Spina bifida occulta (HP:0003298)1.51256517
140Dislocated radial head (HP:0003083)1.51187183
141Flat acetabular roof (HP:0003180)1.50875094
142Coronal craniosynostosis (HP:0004440)1.50364651
143Open mouth (HP:0000194)1.50205676
144Exotropia (HP:0000577)1.49369486
145Abnormality of the astrocytes (HP:0100707)1.48579226
146Astrocytoma (HP:0009592)1.48579226
147Hypoplasia of the maxilla (HP:0000327)1.48573466
148Lower limb amyotrophy (HP:0007210)1.48312841
149Abnormality of the lower motor neuron (HP:0002366)1.47397305
150Thin bony cortex (HP:0002753)1.46591590
151Camptodactyly of toe (HP:0001836)1.45996649
152Long eyelashes (HP:0000527)1.45785842
153Exostoses (HP:0100777)1.45459731
154Increased neuronal autofluorescent lipopigment (HP:0002074)1.45402118
155Polygenic inheritance (HP:0010982)1.45163444

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR23.78401614
2TRIB33.32475219
3CAMK1G2.94745069
4MARK12.91432313
5CAMK1D2.87695499
6ICK2.59349142
7PKN22.59043134
8MAPK152.56701713
9RIPK12.54752558
10SIK22.30079668
11EEF2K2.23808355
12PDGFRA2.07687382
13PTK61.87052226
14AKT31.85796636
15MAP3K101.84297144
16MAP3K91.79016522
17CASK1.71182440
18CSF1R1.66767541
19CAMKK11.65053251
20PAK41.55697407
21TTN1.50301977
22SIK11.39840972
23SMG11.34602633
24ALK1.30492642
25TYRO31.29776536
26PAK21.27777805
27NTRK21.26680833
28FGFR21.26658965
29DDR21.25441717
30CDK121.21583500
31DMPK1.20879534
32SGK4941.20455597
33SGK2231.20455597
34MTOR1.20214849
35CAMKK21.19548426
36EPHB21.18792893
37RET1.18144740
38PAK61.16882354
39PNCK1.14502053
40LATS11.14093086
41TSSK61.10066791
42SGK21.09135940
43PRKD31.05422925
44STK111.05291736
45PDGFRB1.05222977
46EPHA41.03239103
47EPHB11.00271303
48MAP3K40.97294768
49CAMK40.97104847
50SCYL20.95556580
51PRPF4B0.94350759
52RPS6KA20.93754479
53LMTK20.93465692
54PRKD20.90413995
55MARK20.90352827
56KSR10.89288898
57NTRK10.88290216
58PTK20.86908148
59FGFR40.82921927
60CDC42BPA0.80235602
61CDK60.77891500
62ERBB20.76015179
63EPHA20.75688454
64LATS20.74222964
65PRKCH0.72423797
66MET0.71411171
67HIPK20.70673612
68BRD40.68921577
69PHKG20.68419492
70PHKG10.68419492
71MINK10.67702502
72WNK10.65087659
73DAPK20.63750642
74CSNK1A1L0.63630381
75CAMK2B0.63534898
76FGFR30.62229307
77PRKD10.61357559
78CDK11A0.60840509
79ERBB30.60501514
80KSR20.59387929
81TAOK10.59277633
82HCK0.58705734
83CLK10.58613774
84UHMK10.57591230
85MATK0.57209281
86FGFR10.57057438
87BMX0.55759650
88ERN10.53517675
89ROCK20.52153854
90PRKAA10.51539527
91JAK10.51036631
92MAPK130.50988227
93CDK50.50732482
94NEK20.50633665
95MAPK120.50091713
96SGK10.49231575
97ILK0.48926570
98CDK140.48250895
99PKN10.48223453
100NTRK30.47228986
101STK380.46149777
102FYN0.45857042
103INSRR0.44727092
104DYRK1A0.44481596
105SRC0.43893848
106CSNK1G20.43451328
107MELK0.42992174
108FES0.42767850
109GSK3B0.42617886
110CAMK10.42540331
111GRK70.41744824
112MAPK80.41731553
113SGK30.41360596
114RPS6KC10.40364091
115RPS6KL10.40364091
116MAP3K70.40097396
117CDK150.39796791
118DYRK1B0.39719489
119RPS6KA30.39695857
120PRKCZ0.37828163
121STK30.37369554
122PDPK10.37317540
123MAPK90.37230346
124MAPK100.37176979
125MAP3K130.37132701
126ROCK10.36875444
127KIT0.36703769
128RIPK40.36016739
129CDK180.35989902
130EGFR0.35911769
131PDK10.35633417
132GSK3A0.35374051
133PRKCG0.34788158
134MAP3K60.34741191
135MAP2K10.33370259
136CAMK2G0.33137854
137TESK10.32201047
138NEK60.31615692

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.09326339
2Synaptic vesicle cycle_Homo sapiens_hsa047211.68261644
3Chronic myeloid leukemia_Homo sapiens_hsa052201.61065502
4Type II diabetes mellitus_Homo sapiens_hsa049301.60920828
5Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.50350152
6Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.48338832
7Estrogen signaling pathway_Homo sapiens_hsa049151.48296332
8Colorectal cancer_Homo sapiens_hsa052101.46605503
9Neurotrophin signaling pathway_Homo sapiens_hsa047221.42184317
10Glycosaminoglycan degradation_Homo sapiens_hsa005311.40968430
11Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.39328725
12Axon guidance_Homo sapiens_hsa043601.37599738
13Notch signaling pathway_Homo sapiens_hsa043301.35453611
14Glioma_Homo sapiens_hsa052141.33462387
15Renal cell carcinoma_Homo sapiens_hsa052111.32665754
16Focal adhesion_Homo sapiens_hsa045101.29617939
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.26968650
18Osteoclast differentiation_Homo sapiens_hsa043801.26620632
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.26024473
20mTOR signaling pathway_Homo sapiens_hsa041501.24835689
21Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.23250712
22Dilated cardiomyopathy_Homo sapiens_hsa054141.22474285
23AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.19076942
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.18491871
25Proteoglycans in cancer_Homo sapiens_hsa052051.16007848
26Circadian entrainment_Homo sapiens_hsa047131.15568603
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.13892942
28Endometrial cancer_Homo sapiens_hsa052131.13206218
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12246628
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.10878766
31Pancreatic cancer_Homo sapiens_hsa052121.10661568
32Phospholipase D signaling pathway_Homo sapiens_hsa040721.09388014
33Gap junction_Homo sapiens_hsa045401.08729715
34Thyroid hormone synthesis_Homo sapiens_hsa049181.08526048
35Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.08393993
36Platelet activation_Homo sapiens_hsa046111.07854237
37ErbB signaling pathway_Homo sapiens_hsa040121.06924284
38GnRH signaling pathway_Homo sapiens_hsa049121.06826426
39Glutamatergic synapse_Homo sapiens_hsa047241.06327888
40Thyroid hormone signaling pathway_Homo sapiens_hsa049191.06254769
41Long-term potentiation_Homo sapiens_hsa047201.05712214
42Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.05090281
43B cell receptor signaling pathway_Homo sapiens_hsa046621.05078954
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.03784616
45Cholinergic synapse_Homo sapiens_hsa047251.03761347
46MicroRNAs in cancer_Homo sapiens_hsa052061.03134720
47ECM-receptor interaction_Homo sapiens_hsa045121.02656940
48Dorso-ventral axis formation_Homo sapiens_hsa043201.02264049
49Rap1 signaling pathway_Homo sapiens_hsa040151.01013251
50Basal cell carcinoma_Homo sapiens_hsa052171.00758313
51Adherens junction_Homo sapiens_hsa045200.99801540
52Prion diseases_Homo sapiens_hsa050200.99617139
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.98914801
54Phosphatidylinositol signaling system_Homo sapiens_hsa040700.97525034
55Non-small cell lung cancer_Homo sapiens_hsa052230.97515899
56Calcium signaling pathway_Homo sapiens_hsa040200.97041438
57Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95486732
58Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.95274974
59Oxytocin signaling pathway_Homo sapiens_hsa049210.95202753
60Amoebiasis_Homo sapiens_hsa051460.95175058
61Salivary secretion_Homo sapiens_hsa049700.94976974
62Taste transduction_Homo sapiens_hsa047420.94967018
63Renin secretion_Homo sapiens_hsa049240.94444215
64Endocytosis_Homo sapiens_hsa041440.93902251
65Hippo signaling pathway_Homo sapiens_hsa043900.93553319
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.93206813
67AMPK signaling pathway_Homo sapiens_hsa041520.93166914
68Long-term depression_Homo sapiens_hsa047300.92893790
69Longevity regulating pathway - mammal_Homo sapiens_hsa042110.92556501
70MAPK signaling pathway_Homo sapiens_hsa040100.92175200
71Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.91803191
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.90905022
73Dopaminergic synapse_Homo sapiens_hsa047280.90883209
74Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90554095
75VEGF signaling pathway_Homo sapiens_hsa043700.90476753
76Cocaine addiction_Homo sapiens_hsa050300.90113040
77Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.90017435
78Inositol phosphate metabolism_Homo sapiens_hsa005620.89673322
79cAMP signaling pathway_Homo sapiens_hsa040240.89581407
80Prostate cancer_Homo sapiens_hsa052150.89503506
81Regulation of actin cytoskeleton_Homo sapiens_hsa048100.88851435
82Central carbon metabolism in cancer_Homo sapiens_hsa052300.88236369
83Morphine addiction_Homo sapiens_hsa050320.87548611
84Gastric acid secretion_Homo sapiens_hsa049710.87184543
85Hedgehog signaling pathway_Homo sapiens_hsa043400.86253159
86Viral myocarditis_Homo sapiens_hsa054160.85831869
87Tight junction_Homo sapiens_hsa045300.85278483
88Lysosome_Homo sapiens_hsa041420.85189049
89Insulin resistance_Homo sapiens_hsa049310.84449430
90Choline metabolism in cancer_Homo sapiens_hsa052310.84170694
91Insulin secretion_Homo sapiens_hsa049110.84129610
92Lysine degradation_Homo sapiens_hsa003100.82568756
93Toxoplasmosis_Homo sapiens_hsa051450.82177271
94Wnt signaling pathway_Homo sapiens_hsa043100.80590245
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.80086510
96Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.80029120
97Staphylococcus aureus infection_Homo sapiens_hsa051500.79832433
98Small cell lung cancer_Homo sapiens_hsa052220.79813165
99Melanogenesis_Homo sapiens_hsa049160.79632625
100Other glycan degradation_Homo sapiens_hsa005110.79540331
101Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.79055605
102Chemokine signaling pathway_Homo sapiens_hsa040620.78036653
103Bile secretion_Homo sapiens_hsa049760.77932487
104Olfactory transduction_Homo sapiens_hsa047400.77721637
105GABAergic synapse_Homo sapiens_hsa047270.77397740
106Serotonergic synapse_Homo sapiens_hsa047260.76012673
107Glucagon signaling pathway_Homo sapiens_hsa049220.75515268
108Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.74847523
109Pathways in cancer_Homo sapiens_hsa052000.72819592
110Melanoma_Homo sapiens_hsa052180.72179930
111Pertussis_Homo sapiens_hsa051330.72075908
112Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.71987466
113Prolactin signaling pathway_Homo sapiens_hsa049170.71681844
114Insulin signaling pathway_Homo sapiens_hsa049100.71453745
115Amphetamine addiction_Homo sapiens_hsa050310.71394121
116Leishmaniasis_Homo sapiens_hsa051400.70780083
117Ras signaling pathway_Homo sapiens_hsa040140.69945267
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.68885834
119Acute myeloid leukemia_Homo sapiens_hsa052210.68630838
120Ovarian steroidogenesis_Homo sapiens_hsa049130.66273050
121Thyroid cancer_Homo sapiens_hsa052160.65824199
122Bladder cancer_Homo sapiens_hsa052190.64649258
123Pancreatic secretion_Homo sapiens_hsa049720.64248466
124Protein digestion and absorption_Homo sapiens_hsa049740.61957296
125Fatty acid biosynthesis_Homo sapiens_hsa000610.59378340

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