Rank | Gene Set | Z-score |
---|---|---|
1 | barbed-end actin filament capping (GO:0051016) | 4.31323314 |
2 | adhesion of symbiont to host cell (GO:0044650) | 3.75801155 |
3 | virion attachment to host cell (GO:0019062) | 3.75801155 |
4 | blood vessel maturation (GO:0001955) | 3.69114510 |
5 | basement membrane organization (GO:0071711) | 3.67540790 |
6 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.47922361 |
7 | renal filtration (GO:0097205) | 3.39403352 |
8 | alpha-linolenic acid metabolic process (GO:0036109) | 3.38647239 |
9 | glomerular filtration (GO:0003094) | 3.36814671 |
10 | protein retention in ER lumen (GO:0006621) | 3.35162491 |
11 | glomerular basement membrane development (GO:0032836) | 3.35137070 |
12 | tooth mineralization (GO:0034505) | 3.33238431 |
13 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.32083008 |
14 | regulation of extracellular matrix disassembly (GO:0010715) | 3.23942033 |
15 | extracellular fibril organization (GO:0043206) | 3.22244747 |
16 | apoptotic cell clearance (GO:0043277) | 3.20392097 |
17 | lymphangiogenesis (GO:0001946) | 3.16850853 |
18 | surfactant homeostasis (GO:0043129) | 3.13244365 |
19 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.11018361 |
20 | skin morphogenesis (GO:0043589) | 3.10867787 |
21 | regulation of early endosome to late endosome transport (GO:2000641) | 3.07363651 |
22 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.07054077 |
23 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.07005759 |
24 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.06644005 |
25 | endothelial cell chemotaxis (GO:0035767) | 3.06158530 |
26 | hyaluronan catabolic process (GO:0030214) | 3.05524180 |
27 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 3.05325538 |
28 | positive regulation of extracellular matrix organization (GO:1903055) | 3.04849623 |
29 | fibril organization (GO:0097435) | 3.04410287 |
30 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.00966390 |
31 | cell-cell junction maintenance (GO:0045217) | 3.00151226 |
32 | endothelial cell morphogenesis (GO:0001886) | 2.97403343 |
33 | protein localization to endosome (GO:0036010) | 2.96191054 |
34 | adherens junction assembly (GO:0034333) | 2.93437447 |
35 | cell volume homeostasis (GO:0006884) | 2.91653147 |
36 | extracellular matrix assembly (GO:0085029) | 2.90376688 |
37 | endocardial cushion development (GO:0003197) | 2.90245576 |
38 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.86737925 |
39 | atrioventricular valve morphogenesis (GO:0003181) | 2.83726120 |
40 | lymph vessel development (GO:0001945) | 2.82924593 |
41 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.82714316 |
42 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.82697095 |
43 | adhesion of symbiont to host (GO:0044406) | 2.82519228 |
44 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.79272750 |
45 | collagen metabolic process (GO:0032963) | 2.78698218 |
46 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.77710104 |
47 | mannose metabolic process (GO:0006013) | 2.77656961 |
48 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.77617974 |
49 | regulation of cholesterol homeostasis (GO:2000188) | 2.76913311 |
50 | kidney mesenchyme development (GO:0072074) | 2.74522904 |
51 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.73734778 |
52 | regulation of skeletal muscle contraction (GO:0014819) | 2.70955185 |
53 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.69876666 |
54 | cell-substrate adherens junction assembly (GO:0007045) | 2.69244183 |
55 | focal adhesion assembly (GO:0048041) | 2.69244183 |
56 | response to mercury ion (GO:0046689) | 2.68325756 |
57 | sexual reproduction (GO:0019953) | 2.68031196 |
58 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.66977794 |
59 | response to acidic pH (GO:0010447) | 2.66950490 |
60 | sperm capacitation (GO:0048240) | 2.66438618 |
61 | epoxygenase P450 pathway (GO:0019373) | 2.66017884 |
62 | collagen catabolic process (GO:0030574) | 2.65880847 |
63 | protein heterotrimerization (GO:0070208) | 2.64885179 |
64 | venous blood vessel morphogenesis (GO:0048845) | 2.64233016 |
65 | plasma membrane repair (GO:0001778) | 2.63980575 |
66 | semaphorin-plexin signaling pathway (GO:0071526) | 2.61803243 |
67 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.61329336 |
68 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.60490798 |
69 | cell migration involved in heart development (GO:0060973) | 2.59947205 |
70 | positive regulation of receptor recycling (GO:0001921) | 2.59872110 |
71 | ethanol oxidation (GO:0006069) | 2.59062483 |
72 | regulation of cardioblast differentiation (GO:0051890) | 2.58364749 |
73 | fibroblast migration (GO:0010761) | 2.58305491 |
74 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.57897102 |
75 | negative regulation of fibrinolysis (GO:0051918) | 2.56491243 |
76 | pinocytosis (GO:0006907) | 2.56012813 |
77 | extracellular matrix disassembly (GO:0022617) | 2.55594900 |
78 | peptidyl-proline hydroxylation (GO:0019511) | 2.55053185 |
79 | multicellular organismal catabolic process (GO:0044243) | 2.52809102 |
80 | positive regulation of fatty acid oxidation (GO:0046321) | 2.52207603 |
81 | regulation of extracellular matrix organization (GO:1903053) | 2.52196067 |
82 | keratan sulfate catabolic process (GO:0042340) | 2.52158938 |
83 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.51683521 |
84 | chondrocyte proliferation (GO:0035988) | 2.51440570 |
85 | UV protection (GO:0009650) | 2.50938851 |
86 | myelination in peripheral nervous system (GO:0022011) | 2.50735753 |
87 | peripheral nervous system axon ensheathment (GO:0032292) | 2.50735753 |
88 | complement activation, alternative pathway (GO:0006957) | 2.50252822 |
89 | multicellular organismal metabolic process (GO:0044236) | 2.49744006 |
90 | cochlea morphogenesis (GO:0090103) | 2.49343725 |
91 | regulation of endothelial cell differentiation (GO:0045601) | 2.49335771 |
92 | embryo implantation (GO:0007566) | 2.48891356 |
93 | cortical actin cytoskeleton organization (GO:0030866) | 2.46007915 |
94 | cellular response to pH (GO:0071467) | 2.45865361 |
95 | regulation of complement activation (GO:0030449) | 2.44968383 |
96 | metanephric mesenchyme development (GO:0072075) | 2.43974315 |
97 | L-phenylalanine catabolic process (GO:0006559) | 2.43239166 |
98 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.43239166 |
99 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.42516686 |
100 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 2.42372043 |
101 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.41598665 |
102 | regulation of protein activation cascade (GO:2000257) | 2.40947801 |
103 | sulfur amino acid catabolic process (GO:0000098) | 2.39392824 |
104 | regulation of plasminogen activation (GO:0010755) | 2.39221406 |
105 | chondroitin sulfate catabolic process (GO:0030207) | 2.39101836 |
106 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.39062098 |
107 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.38549065 |
108 | blood vessel endothelial cell migration (GO:0043534) | 2.38521417 |
109 | epithelial cell-cell adhesion (GO:0090136) | 2.38488984 |
110 | toxin metabolic process (GO:0009404) | 2.38354874 |
111 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.38251921 |
112 | L-phenylalanine metabolic process (GO:0006558) | 2.37627136 |
113 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.37627136 |
114 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 2.37349574 |
115 | cortical cytoskeleton organization (GO:0030865) | 2.37025729 |
116 | fatty acid transmembrane transport (GO:1902001) | 2.36513971 |
117 | positive regulation of triglyceride metabolic process (GO:0090208) | 2.35699518 |
118 | stress fiber assembly (GO:0043149) | 2.35600327 |
119 | collagen fibril organization (GO:0030199) | 2.35441743 |
120 | negative regulation of catenin import into nucleus (GO:0035414) | 2.35276022 |
121 | hormone catabolic process (GO:0042447) | 2.34611721 |
122 | carnitine shuttle (GO:0006853) | 2.34555781 |
123 | cell proliferation involved in metanephros development (GO:0072203) | 2.34176973 |
124 | regulation of p38MAPK cascade (GO:1900744) | 2.34157949 |
125 | glycosaminoglycan catabolic process (GO:0006027) | 2.34013762 |
126 | lung lobe morphogenesis (GO:0060463) | 2.33757972 |
127 | bone trabecula formation (GO:0060346) | 2.32271846 |
128 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.31418847 |
129 | regulation of apoptotic cell clearance (GO:2000425) | 2.31133849 |
130 | regulation of fatty acid oxidation (GO:0046320) | 2.30841210 |
131 | high-density lipoprotein particle remodeling (GO:0034375) | 2.30720796 |
132 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.30677929 |
133 | fatty acid beta-oxidation (GO:0006635) | 2.30600811 |
134 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.30419071 |
135 | regulation of ARF GTPase activity (GO:0032312) | 2.30073956 |
136 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.29568027 |
137 | axon extension involved in axon guidance (GO:0048846) | 2.29568027 |
138 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.29445016 |
139 | xenobiotic catabolic process (GO:0042178) | 2.29330783 |
140 | heart trabecula formation (GO:0060347) | 2.29175229 |
141 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.28582817 |
142 | sarcomere organization (GO:0045214) | 2.28222792 |
143 | reverse cholesterol transport (GO:0043691) | 2.28202207 |
144 | cardiac myofibril assembly (GO:0055003) | 2.28190818 |
145 | positive regulation of Rho protein signal transduction (GO:0035025) | 2.27640870 |
146 | type B pancreatic cell proliferation (GO:0044342) | 2.27493485 |
147 | endocytic recycling (GO:0032456) | 2.27409170 |
148 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.27260473 |
149 | hemidesmosome assembly (GO:0031581) | 2.27098914 |
150 | negative regulation of heart growth (GO:0061117) | 2.27020701 |
151 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 2.27020701 |
152 | positive regulation of glycogen metabolic process (GO:0070875) | 2.26874891 |
153 | endodermal cell differentiation (GO:0035987) | 2.26228576 |
154 | negative regulation of cartilage development (GO:0061037) | 2.25240097 |
155 | cell-substrate junction assembly (GO:0007044) | 2.25087392 |
156 | low-density lipoprotein particle clearance (GO:0034383) | 2.24582864 |
157 | response to laminar fluid shear stress (GO:0034616) | 2.24253542 |
158 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.24064322 |
159 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.23864207 |
160 | lysine catabolic process (GO:0006554) | 2.23331482 |
161 | lysine metabolic process (GO:0006553) | 2.23331482 |
162 | receptor recycling (GO:0001881) | 2.22797221 |
163 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.22165073 |
164 | protein carboxylation (GO:0018214) | 2.22130377 |
165 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.22130377 |
166 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.21941980 |
167 | positive regulation of p38MAPK cascade (GO:1900745) | 2.21219832 |
168 | cellular response to growth hormone stimulus (GO:0071378) | 2.21082936 |
169 | opsonization (GO:0008228) | 2.20188437 |
170 | regulation of cholesterol metabolic process (GO:0090181) | 2.19906247 |
171 | morphogenesis of an endothelium (GO:0003159) | 2.18983016 |
172 | endothelial tube morphogenesis (GO:0061154) | 2.18983016 |
173 | positive regulation of blood coagulation (GO:0030194) | 2.18056338 |
174 | positive regulation of hemostasis (GO:1900048) | 2.18056338 |
175 | plasma lipoprotein particle clearance (GO:0034381) | 2.18032808 |
176 | midgut development (GO:0007494) | 2.17779566 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 4.37112503 |
2 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.88193861 |
3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.58668190 |
4 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.50946150 |
5 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.95528852 |
6 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.90209053 |
7 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.67232319 |
8 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.54529021 |
9 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.49326007 |
10 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.41351735 |
11 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.31900312 |
12 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.16530697 |
13 | * GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.15098229 |
14 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.12165481 |
15 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.09037945 |
16 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.05779991 |
17 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.05451353 |
18 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.04331089 |
19 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.96958089 |
20 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.93390710 |
21 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.92714413 |
22 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.85799688 |
23 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.84726618 |
24 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.77497359 |
25 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.77010669 |
26 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.77010669 |
27 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.76234991 |
28 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.73709157 |
29 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69285149 |
30 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.65314401 |
31 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.63857408 |
32 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.61238739 |
33 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.60962242 |
34 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.60779173 |
35 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.60162496 |
36 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.58931471 |
37 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.58128336 |
38 | P68_20966046_ChIP-Seq_HELA_Human | 1.55912233 |
39 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.55438640 |
40 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.52886532 |
41 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.52060106 |
42 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.49867112 |
43 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.48326382 |
44 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.46633022 |
45 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.46546085 |
46 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.43799258 |
47 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.41908382 |
48 | CJUN_26792858_Chip-Seq_BT549_Human | 1.41152074 |
49 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.37976197 |
50 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.37440697 |
51 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.37306414 |
52 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.35352916 |
53 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.33322541 |
54 | * DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.33233068 |
55 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.31490612 |
56 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.30625079 |
57 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.28895586 |
58 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.27661648 |
59 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.26208649 |
60 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.25912215 |
61 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.25787604 |
62 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.25395260 |
63 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.24988494 |
64 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.24751562 |
65 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.24383180 |
66 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.23773114 |
67 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.20692241 |
68 | * SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.20076095 |
69 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.18509413 |
70 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.15999087 |
71 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.15824340 |
72 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.15251869 |
73 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14520578 |
74 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.14142876 |
75 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.13372353 |
76 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.12502164 |
77 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.12502164 |
78 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.11539528 |
79 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.10634336 |
80 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.09802170 |
81 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.09724976 |
82 | * RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.07975484 |
83 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.07083914 |
84 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.07077750 |
85 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.06497666 |
86 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.05788494 |
87 | GATA1_19941826_ChIP-Seq_K562_Human | 1.05633078 |
88 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.05223066 |
89 | ATF3_27146783_Chip-Seq_COLON_Human | 1.04848405 |
90 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.03570417 |
91 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.02966468 |
92 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.02430396 |
93 | SA1_27219007_Chip-Seq_Bcells_Human | 1.01720411 |
94 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.00361939 |
95 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.00306381 |
96 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.00126464 |
97 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.99761539 |
98 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.98972545 |
99 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.97916175 |
100 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.95944204 |
101 | KDM2B_26808549_Chip-Seq_K562_Human | 0.95810698 |
102 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.95667932 |
103 | * VDR_24763502_ChIP-Seq_THP-1_Human | 0.95414462 |
104 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.95376997 |
105 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.94742013 |
106 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.94631486 |
107 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.94109081 |
108 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.94051785 |
109 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.93858506 |
110 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.93788014 |
111 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.93576111 |
112 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.93435745 |
113 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.93133160 |
114 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.92648957 |
115 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.92457478 |
116 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.92207170 |
117 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.92165707 |
118 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.90539152 |
119 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.90273702 |
120 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.89424465 |
121 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.89215882 |
122 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.89094844 |
123 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.89094844 |
124 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.87443716 |
125 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.87283465 |
126 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.87171812 |
127 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.85716201 |
128 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.85716201 |
129 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.84794608 |
130 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.84412738 |
131 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.84146281 |
132 | GATA2_19941826_ChIP-Seq_K562_Human | 0.84015956 |
133 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.83466017 |
134 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.83453938 |
135 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.83278284 |
136 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.81620014 |
137 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.81302246 |
138 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.80488567 |
139 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.79852379 |
140 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.79539568 |
141 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.78935788 |
142 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.78725761 |
143 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.77730655 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010368_abnormal_lymphatic_system | 4.38296932 |
2 | MP0008438_abnormal_cutaneous_collagen | 4.14784555 |
3 | MP0004272_abnormal_basement_membrane | 3.34284294 |
4 | MP0003705_abnormal_hypodermis_morpholog | 3.15067774 |
5 | MP0005257_abnormal_intraocular_pressure | 2.81601017 |
6 | MP0003279_aneurysm | 2.80353264 |
7 | MP0001958_emphysema | 2.72729657 |
8 | MP0005503_abnormal_tendon_morphology | 2.69326505 |
9 | MP0001879_abnormal_lymphatic_vessel | 2.47329586 |
10 | MP0005275_abnormal_skin_tensile | 2.21464754 |
11 | MP0000751_myopathy | 2.09992884 |
12 | MP0008875_abnormal_xenobiotic_pharmacok | 2.09479187 |
13 | MP0001849_ear_inflammation | 2.07594564 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.07398606 |
15 | MP0004084_abnormal_cardiac_muscle | 2.03486419 |
16 | MP0009384_cardiac_valve_regurgitation | 1.99098170 |
17 | MP0005623_abnormal_meninges_morphology | 1.98108056 |
18 | MP0005670_abnormal_white_adipose | 1.93024807 |
19 | MP0009840_abnormal_foam_cell | 1.89928293 |
20 | MP0005365_abnormal_bile_salt | 1.86684457 |
21 | MP0004858_abnormal_nervous_system | 1.85885856 |
22 | MP0003566_abnormal_cell_adhesion | 1.78434282 |
23 | MP0002139_abnormal_hepatobiliary_system | 1.70421082 |
24 | MP0005410_abnormal_fertilization | 1.68129605 |
25 | MP0004036_abnormal_muscle_relaxation | 1.67491605 |
26 | MP0003950_abnormal_plasma_membrane | 1.66765502 |
27 | MP0000678_abnormal_parathyroid_gland | 1.64198363 |
28 | MP0000767_abnormal_smooth_muscle | 1.61262129 |
29 | MP0006138_congestive_heart_failure | 1.60840731 |
30 | MP0000749_muscle_degeneration | 1.59478664 |
31 | MP0005360_urolithiasis | 1.53431785 |
32 | MP0001348_abnormal_lacrimal_gland | 1.48582534 |
33 | MP0001542_abnormal_bone_strength | 1.47997068 |
34 | MP0009278_abnormal_bone_marrow | 1.47533084 |
35 | MP0006054_spinal_hemorrhage | 1.47172319 |
36 | MP0003172_abnormal_lysosome_physiology | 1.46302286 |
37 | MP0010030_abnormal_orbit_morphology | 1.45020293 |
38 | MP0003329_amyloid_beta_deposits | 1.43244538 |
39 | MP0002295_abnormal_pulmonary_circulatio | 1.41371290 |
40 | MP0002108_abnormal_muscle_morphology | 1.39629478 |
41 | MP0005409_darkened_coat_color | 1.39612188 |
42 | MP0004087_abnormal_muscle_fiber | 1.39382103 |
43 | MP0005330_cardiomyopathy | 1.35774578 |
44 | MP0005451_abnormal_body_composition | 1.35668613 |
45 | MP0010329_abnormal_lipoprotein_level | 1.33098343 |
46 | MP0003828_pulmonary_edema | 1.32992667 |
47 | MP0009780_abnormal_chondrocyte_physiolo | 1.32282844 |
48 | MP0010630_abnormal_cardiac_muscle | 1.29692510 |
49 | MP0005167_abnormal_blood-brain_barrier | 1.27831383 |
50 | MP0002998_abnormal_bone_remodeling | 1.27250122 |
51 | MP0000733_abnormal_muscle_development | 1.26027053 |
52 | MP0002128_abnormal_blood_circulation | 1.25540541 |
53 | MP0002837_dystrophic_cardiac_calcinosis | 1.25375787 |
54 | MP0004130_abnormal_muscle_cell | 1.24879912 |
55 | MP0004510_myositis | 1.24285800 |
56 | MP0002933_joint_inflammation | 1.20977308 |
57 | MP0001544_abnormal_cardiovascular_syste | 1.20080720 |
58 | MP0005385_cardiovascular_system_phenoty | 1.20080720 |
59 | MP0005085_abnormal_gallbladder_physiolo | 1.19093497 |
60 | MP0005508_abnormal_skeleton_morphology | 1.19037460 |
61 | MP0000750_abnormal_muscle_regeneration | 1.18883480 |
62 | MP0000534_abnormal_ureter_morphology | 1.16555076 |
63 | MP0005595_abnormal_vascular_smooth | 1.14145309 |
64 | MP0000604_amyloidosis | 1.13730303 |
65 | MP0003075_altered_response_to | 1.10347704 |
66 | MP0005390_skeleton_phenotype | 1.10153860 |
67 | MP0003252_abnormal_bile_duct | 1.07405007 |
68 | * MP0003091_abnormal_cell_migration | 1.06258783 |
69 | MP0005083_abnormal_biliary_tract | 1.03218668 |
70 | MP0003115_abnormal_respiratory_system | 1.02434106 |
71 | MP0003453_abnormal_keratinocyte_physiol | 1.02103360 |
72 | MP0001614_abnormal_blood_vessel | 1.02065194 |
73 | MP0000343_altered_response_to | 1.02016732 |
74 | MP0005666_abnormal_adipose_tissue | 1.00604916 |
75 | MP0003879_abnormal_hair_cell | 1.00594909 |
76 | MP0002269_muscular_atrophy | 1.00275343 |
77 | MP0000747_muscle_weakness | 0.99585049 |
78 | MP0005620_abnormal_muscle_contractility | 0.98795697 |
79 | MP0005165_increased_susceptibility_to | 0.98438429 |
80 | MP0003385_abnormal_body_wall | 0.98257732 |
81 | MP0009250_abnormal_appendicular_skeleto | 0.96595056 |
82 | MP0001533_abnormal_skeleton_physiology | 0.95966505 |
83 | MP0003300_gastrointestinal_ulcer | 0.95396558 |
84 | MP0000681_abnormal_thyroid_gland | 0.94952306 |
85 | MP0005332_abnormal_amino_acid | 0.94888484 |
86 | MP0000249_abnormal_blood_vessel | 0.94718645 |
87 | MP0005377_hearing/vestibular/ear_phenot | 0.94660478 |
88 | MP0003878_abnormal_ear_physiology | 0.94660478 |
89 | MP0003942_abnormal_urinary_system | 0.94580163 |
90 | MP0003690_abnormal_glial_cell | 0.93765653 |
91 | * MP0005023_abnormal_wound_healing | 0.93194331 |
92 | MP0005375_adipose_tissue_phenotype | 0.92658326 |
93 | MP0002972_abnormal_cardiac_muscle | 0.92550521 |
94 | MP0005369_muscle_phenotype | 0.92537136 |
95 | MP0000759_abnormal_skeletal_muscle | 0.91799054 |
96 | MP0002877_abnormal_melanocyte_morpholog | 0.91759604 |
97 | MP0008775_abnormal_heart_ventricle | 0.90385302 |
98 | MP0000013_abnormal_adipose_tissue | 0.90322177 |
99 | MP0002168_other_aberrant_phenotype | 0.89963405 |
100 | MP0002118_abnormal_lipid_homeostasis | 0.89744776 |
101 | MP0004145_abnormal_muscle_electrophysio | 0.88850376 |
102 | MP0000566_synostosis | 0.87771180 |
103 | MP0000003_abnormal_adipose_tissue | 0.86760824 |
104 | MP0002089_abnormal_postnatal_growth/wei | 0.86014576 |
105 | MP0002106_abnormal_muscle_physiology | 0.85749992 |
106 | MP0004883_abnormal_blood_vessel | 0.85184321 |
107 | MP0002925_abnormal_cardiovascular_devel | 0.85153578 |
108 | MP0002254_reproductive_system_inflammat | 0.85069302 |
109 | MP0009053_abnormal_anal_canal | 0.84800594 |
110 | MP0000163_abnormal_cartilage_morphology | 0.84726545 |
111 | MP0001243_abnormal_dermal_layer | 0.84657022 |
112 | MP0005388_respiratory_system_phenotype | 0.84621048 |
113 | MP0002133_abnormal_respiratory_system | 0.84621048 |
114 | MP0002249_abnormal_larynx_morphology | 0.84457432 |
115 | MP0000858_altered_metastatic_potential | 0.84345625 |
116 | MP0003724_increased_susceptibility_to | 0.84172946 |
117 | MP0005076_abnormal_cell_differentiation | 0.84024715 |
118 | MP0002060_abnormal_skin_morphology | 0.83370580 |
119 | MP0002896_abnormal_bone_mineralization | 0.82988070 |
120 | MP0001270_distended_abdomen | 0.80480488 |
121 | MP0000230_abnormal_systemic_arterial | 0.80418980 |
122 | MP0008260_abnormal_autophagy | 0.80175171 |
123 | MP0002971_abnormal_brown_adipose | 0.79395103 |
124 | MP0005058_abnormal_lysosome_morphology | 0.79371615 |
125 | MP0000266_abnormal_heart_morphology | 0.79285179 |
126 | MP0004484_altered_response_of | 0.78821441 |
127 | MP0005319_abnormal_enzyme/_coenzyme | 0.77513866 |
128 | MP0000762_abnormal_tongue_morphology | 0.77476676 |
129 | MP0003634_abnormal_glial_cell | 0.75950341 |
130 | MP0001299_abnormal_eye_distance/ | 0.75210897 |
131 | MP0005164_abnormal_response_to | 0.75035618 |
132 | MP0004233_abnormal_muscle_weight | 0.73113290 |
133 | MP0005171_absent_coat_pigmentation | 0.68618640 |
134 | MP0002113_abnormal_skeleton_development | 0.68344055 |
135 | MP0002115_abnormal_skeleton_extremities | 0.68309548 |
136 | MP0003303_peritoneal_inflammation | 0.68013709 |
137 | MP0003448_altered_tumor_morphology | 0.67811658 |
138 | MP0001915_intracranial_hemorrhage | 0.66835759 |
139 | MP0002932_abnormal_joint_morphology | 0.66791504 |
140 | MP0000049_abnormal_middle_ear | 0.65835111 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 4.73446749 |
2 | Broad metatarsal (HP:0001783) | 4.59599765 |
3 | Premature rupture of membranes (HP:0001788) | 4.16256117 |
4 | Shallow orbits (HP:0000586) | 3.77425361 |
5 | Deep venous thrombosis (HP:0002625) | 3.39981502 |
6 | Muscle fiber splitting (HP:0003555) | 3.35752873 |
7 | Vertebral compression fractures (HP:0002953) | 3.23718613 |
8 | Hyporeflexia of lower limbs (HP:0002600) | 3.22400588 |
9 | Cerebral aneurysm (HP:0004944) | 3.18575515 |
10 | Spinal rigidity (HP:0003306) | 3.08757939 |
11 | Increased connective tissue (HP:0009025) | 3.07722324 |
12 | Type 1 muscle fiber predominance (HP:0003803) | 3.04350669 |
13 | Aortic dissection (HP:0002647) | 3.01453670 |
14 | Ankle contracture (HP:0006466) | 2.97917874 |
15 | Asymmetric septal hypertrophy (HP:0001670) | 2.89663770 |
16 | Obstructive sleep apnea (HP:0002870) | 2.88748665 |
17 | Aortic aneurysm (HP:0004942) | 2.83894927 |
18 | Polycythemia (HP:0001901) | 2.72235494 |
19 | Mesangial abnormality (HP:0001966) | 2.69867620 |
20 | Bronchomalacia (HP:0002780) | 2.68481368 |
21 | Nuclear cataract (HP:0100018) | 2.62978418 |
22 | Joint stiffness (HP:0001387) | 2.60790490 |
23 | Upper limb amyotrophy (HP:0009129) | 2.58613652 |
24 | Distal upper limb amyotrophy (HP:0007149) | 2.58613652 |
25 | Right ventricular cardiomyopathy (HP:0011663) | 2.55952519 |
26 | Exercise-induced myalgia (HP:0003738) | 2.53927895 |
27 | Difficulty running (HP:0009046) | 2.53600834 |
28 | Abnormality of complement system (HP:0005339) | 2.51807528 |
29 | Atrophic scars (HP:0001075) | 2.47831214 |
30 | Increased variability in muscle fiber diameter (HP:0003557) | 2.47063807 |
31 | Bladder diverticulum (HP:0000015) | 2.47028844 |
32 | Achilles tendon contracture (HP:0001771) | 2.45125467 |
33 | Distal lower limb muscle weakness (HP:0009053) | 2.42995467 |
34 | Mitral regurgitation (HP:0001653) | 2.39977643 |
35 | Esophageal varix (HP:0002040) | 2.39687859 |
36 | Dysostosis multiplex (HP:0000943) | 2.39438893 |
37 | Biconcave vertebral bodies (HP:0004586) | 2.39294081 |
38 | Vascular tortuosity (HP:0004948) | 2.38972946 |
39 | Osteolytic defects of the hand bones (HP:0009699) | 2.35846855 |
40 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.35846855 |
41 | Dilatation of the ascending aorta (HP:0005111) | 2.35571147 |
42 | Round ear (HP:0100830) | 2.34785849 |
43 | Cardiovascular calcification (HP:0011915) | 2.34558227 |
44 | Genu recurvatum (HP:0002816) | 2.32745361 |
45 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.30857513 |
46 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.29947671 |
47 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.29947671 |
48 | Abnormality of glycolipid metabolism (HP:0010969) | 2.29947671 |
49 | Abnormality of the Achilles tendon (HP:0005109) | 2.29805885 |
50 | Hypoalphalipoproteinemia (HP:0003233) | 2.27807918 |
51 | Slender build (HP:0001533) | 2.26942249 |
52 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.26799949 |
53 | Mucopolysacchariduria (HP:0008155) | 2.26799949 |
54 | Exercise-induced muscle cramps (HP:0003710) | 2.26056070 |
55 | Aneurysm (HP:0002617) | 2.23180709 |
56 | Pulmonary artery stenosis (HP:0004415) | 2.22901207 |
57 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.22002196 |
58 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.22002196 |
59 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.22002196 |
60 | Arterial tortuosity (HP:0005116) | 2.20794315 |
61 | Hyperextensible skin (HP:0000974) | 2.18474535 |
62 | Hypoglycemic coma (HP:0001325) | 2.17479564 |
63 | Hyperacusis (HP:0010780) | 2.16546897 |
64 | Thin bony cortex (HP:0002753) | 2.16250478 |
65 | Complement deficiency (HP:0004431) | 2.15315841 |
66 | Peritonitis (HP:0002586) | 2.15248699 |
67 | Xanthomatosis (HP:0000991) | 2.14123770 |
68 | Turricephaly (HP:0000262) | 2.13277238 |
69 | Distal lower limb amyotrophy (HP:0008944) | 2.11345343 |
70 | Joint laxity (HP:0001388) | 2.10556464 |
71 | Myoglobinuria (HP:0002913) | 2.09976697 |
72 | Lymphangioma (HP:0100764) | 2.09909784 |
73 | Aortic regurgitation (HP:0001659) | 2.08362875 |
74 | Abnormality of the acetabulum (HP:0003170) | 2.06061083 |
75 | Hematochezia (HP:0002573) | 2.05382532 |
76 | Nonimmune hydrops fetalis (HP:0001790) | 2.04727918 |
77 | Vascular calcification (HP:0004934) | 2.04431272 |
78 | Lipoatrophy (HP:0100578) | 2.04195494 |
79 | Follicular hyperkeratosis (HP:0007502) | 2.04168843 |
80 | Broad face (HP:0000283) | 2.03371484 |
81 | Ventricular tachycardia (HP:0004756) | 2.01812050 |
82 | Hand muscle atrophy (HP:0009130) | 2.00382747 |
83 | Wormian bones (HP:0002645) | 2.00263768 |
84 | Mitral valve prolapse (HP:0001634) | 1.98827288 |
85 | Abnormality of the nasal mucosa (HP:0000433) | 1.98123332 |
86 | Short nail (HP:0001799) | 1.97667144 |
87 | Ectopia lentis (HP:0001083) | 1.97206985 |
88 | Coronal craniosynostosis (HP:0004440) | 1.97149008 |
89 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.96711659 |
90 | Short hallux (HP:0010109) | 1.94563738 |
91 | Generalized amyotrophy (HP:0003700) | 1.94087796 |
92 | Blue sclerae (HP:0000592) | 1.94002541 |
93 | Visceral angiomatosis (HP:0100761) | 1.93636650 |
94 | Abnormality of dentin (HP:0010299) | 1.93233068 |
95 | Natal tooth (HP:0000695) | 1.92783255 |
96 | Myotonia (HP:0002486) | 1.92739455 |
97 | Wide anterior fontanel (HP:0000260) | 1.91928785 |
98 | Sudden death (HP:0001699) | 1.91889037 |
99 | Cervical subluxation (HP:0003308) | 1.91416814 |
100 | Muscle stiffness (HP:0003552) | 1.90606196 |
101 | Acanthosis nigricans (HP:0000956) | 1.90250197 |
102 | Elbow flexion contracture (HP:0002987) | 1.90212318 |
103 | Aplasia of the phalanges of the hand (HP:0009802) | 1.90198454 |
104 | Aplasia involving bones of the extremities (HP:0009825) | 1.90198454 |
105 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.90198454 |
106 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.90041397 |
107 | Neonatal death (HP:0003811) | 1.89871012 |
108 | Enlarged penis (HP:0000040) | 1.89857196 |
109 | Atelectasis (HP:0100750) | 1.88636302 |
110 | EMG: myopathic abnormalities (HP:0003458) | 1.88144577 |
111 | Mitral stenosis (HP:0001718) | 1.87593936 |
112 | Axonal loss (HP:0003447) | 1.87518543 |
113 | Muscle fiber inclusion bodies (HP:0100299) | 1.86702511 |
114 | Bell-shaped thorax (HP:0001591) | 1.86112601 |
115 | Neurofibrillary tangles (HP:0002185) | 1.85515863 |
116 | Wrist flexion contracture (HP:0001239) | 1.85367656 |
117 | Humeroradial synostosis (HP:0003041) | 1.85102066 |
118 | Synostosis involving the elbow (HP:0003938) | 1.85102066 |
119 | Spontaneous hematomas (HP:0007420) | 1.84738320 |
120 | Systemic lupus erythematosus (HP:0002725) | 1.84395444 |
121 | Abnormality of the calf musculature (HP:0001430) | 1.83772851 |
122 | Disproportionate tall stature (HP:0001519) | 1.83389909 |
123 | Hemangiomatosis (HP:0007461) | 1.83027433 |
124 | Fragile skin (HP:0001030) | 1.82450821 |
125 | Hyperlipoproteinemia (HP:0010980) | 1.82349142 |
126 | Atrioventricular block (HP:0001678) | 1.82279100 |
127 | Stridor (HP:0010307) | 1.82184544 |
128 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.82040297 |
129 | Tarsal synostosis (HP:0008368) | 1.81906734 |
130 | Hemorrhage of the eye (HP:0011885) | 1.80341582 |
131 | Ulnar bowing (HP:0003031) | 1.79011423 |
132 | Venous abnormality (HP:0002624) | 1.78691840 |
133 | Cerebral inclusion bodies (HP:0100314) | 1.78416123 |
134 | Hyperkalemia (HP:0002153) | 1.78047686 |
135 | Long toe (HP:0010511) | 1.77423028 |
136 | Atrial fibrillation (HP:0005110) | 1.77252845 |
137 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.77181990 |
138 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.76968580 |
139 | Hypoplastic left heart (HP:0004383) | 1.76887747 |
140 | Bowel diverticulosis (HP:0005222) | 1.76400896 |
141 | Bowing of the arm (HP:0006488) | 1.76094509 |
142 | Bowed forearm bones (HP:0003956) | 1.76094509 |
143 | Spondylolisthesis (HP:0003302) | 1.75112208 |
144 | Hypoventilation (HP:0002791) | 1.74970447 |
145 | Neonatal short-limb short stature (HP:0008921) | 1.74551457 |
146 | Coxa vara (HP:0002812) | 1.74362849 |
147 | Soft skin (HP:0000977) | 1.74257916 |
148 | Glomerulonephritis (HP:0000099) | 1.74134256 |
149 | Ulnar deviation of the wrist (HP:0003049) | 1.73448182 |
150 | Difficulty climbing stairs (HP:0003551) | 1.72966593 |
151 | Nasal polyposis (HP:0100582) | 1.71939952 |
152 | Abnormal delivery (HP:0001787) | 1.71761111 |
153 | Aortic valve stenosis (HP:0001650) | 1.71575287 |
154 | Camptodactyly of toe (HP:0001836) | 1.71531430 |
155 | Myocardial infarction (HP:0001658) | 1.69668403 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TIE1 | 4.67292722 |
2 | TRIB3 | 4.03769907 |
3 | TTN | 3.22873160 |
4 | TGFBR2 | 3.01754773 |
5 | ERN1 | 2.63207168 |
6 | EPHB1 | 2.62537616 |
7 | RIPK1 | 2.57406900 |
8 | SIK1 | 2.39254934 |
9 | KDR | 2.22102035 |
10 | EPHB2 | 2.21723383 |
11 | MYLK | 1.93836646 |
12 | MAP2K3 | 1.93343638 |
13 | MET | 1.92168894 |
14 | PTK6 | 1.75807551 |
15 | BCKDK | 1.73383022 |
16 | PKN2 | 1.69152686 |
17 | LATS1 | 1.68694235 |
18 | CDC42BPA | 1.67332209 |
19 | PRPF4B | 1.67271414 |
20 | SMG1 | 1.66400390 |
21 | LMTK2 | 1.61710655 |
22 | DMPK | 1.58099485 |
23 | PTK2B | 1.52592913 |
24 | STK38 | 1.52544400 |
25 | IRAK3 | 1.52399008 |
26 | PDGFRA | 1.52134314 |
27 | MST1R | 1.51017695 |
28 | WNK4 | 1.50780675 |
29 | EEF2K | 1.50222392 |
30 | PHKG1 | 1.49612812 |
31 | PHKG2 | 1.49612812 |
32 | EPHA2 | 1.48671555 |
33 | PAK4 | 1.48638415 |
34 | DDR2 | 1.41631832 |
35 | FGFR2 | 1.41500113 |
36 | BMX | 1.37936186 |
37 | ARAF | 1.36190574 |
38 | PRKD3 | 1.33810846 |
39 | NME2 | 1.32140972 |
40 | MOS | 1.25278882 |
41 | LRRK2 | 1.25216564 |
42 | ILK | 1.24861105 |
43 | CAMK1D | 1.23850742 |
44 | TGFBR1 | 1.22513415 |
45 | RPS6KA2 | 1.20466781 |
46 | PTK2 | 1.18172035 |
47 | MAP3K7 | 1.17684045 |
48 | STK39 | 1.17206383 |
49 | MAP3K11 | 1.17180069 |
50 | LIMK1 | 1.14665061 |
51 | ICK | 1.12504175 |
52 | FGFR4 | 1.12382604 |
53 | ABL2 | 1.12012023 |
54 | CAMK1G | 1.11440901 |
55 | PDK2 | 1.10789150 |
56 | MAP3K13 | 1.06327066 |
57 | CDK12 | 1.02919699 |
58 | TAOK2 | 1.00852119 |
59 | OBSCN | 0.99848605 |
60 | PAK2 | 0.98493770 |
61 | INSRR | 0.97866836 |
62 | PDK4 | 0.97527754 |
63 | PDK3 | 0.97527754 |
64 | NEK9 | 0.93952896 |
65 | PIK3CA | 0.92122763 |
66 | PRKD1 | 0.91321962 |
67 | MAP2K2 | 0.87957999 |
68 | MUSK | 0.87010742 |
69 | MAP3K3 | 0.81986034 |
70 | FER | 0.81897837 |
71 | FGFR1 | 0.81440371 |
72 | PAK3 | 0.81073568 |
73 | RPS6KL1 | 0.79383516 |
74 | RPS6KC1 | 0.79383516 |
75 | MAP3K1 | 0.79318008 |
76 | MAPK12 | 0.78672382 |
77 | KSR2 | 0.78021658 |
78 | NTRK1 | 0.75993147 |
79 | ROCK1 | 0.75014836 |
80 | WNK1 | 0.74563159 |
81 | BRD4 | 0.74298818 |
82 | TBK1 | 0.73094668 |
83 | PRKCH | 0.71531314 |
84 | EPHA3 | 0.70633547 |
85 | MAPK15 | 0.70549305 |
86 | LATS2 | 0.69732068 |
87 | MARK2 | 0.68425097 |
88 | MAPKAPK3 | 0.68215546 |
89 | ROCK2 | 0.66852212 |
90 | RET | 0.66806662 |
91 | PIK3CG | 0.64845815 |
92 | MTOR | 0.64711626 |
93 | PDGFRB | 0.64218236 |
94 | PDPK1 | 0.63408301 |
95 | HIPK2 | 0.59202221 |
96 | MAPK7 | 0.58561957 |
97 | ZAP70 | 0.57288093 |
98 | PRKG2 | 0.56644537 |
99 | RPS6KA6 | 0.56428722 |
100 | PIM2 | 0.55242935 |
101 | PDK1 | 0.54788974 |
102 | TESK2 | 0.54694299 |
103 | BRAF | 0.53186158 |
104 | GSK3A | 0.52226134 |
105 | CAMK2G | 0.49798451 |
106 | TRPM7 | 0.48907558 |
107 | NLK | 0.48527056 |
108 | TESK1 | 0.45245552 |
109 | PRKD2 | 0.44930022 |
110 | TAOK1 | 0.44875351 |
111 | ERBB2 | 0.44263491 |
112 | MAPK4 | 0.44059875 |
113 | PRKAA2 | 0.42835813 |
114 | CAMK4 | 0.42045293 |
115 | KIT | 0.41958928 |
116 | STK3 | 0.41785175 |
117 | MAP3K8 | 0.41666824 |
118 | TYK2 | 0.40688511 |
119 | MAPK11 | 0.38730720 |
120 | MAPKAPK5 | 0.38546202 |
121 | SRC | 0.38391948 |
122 | PKN1 | 0.38320624 |
123 | PAK1 | 0.37976825 |
124 | SGK223 | 0.37740839 |
125 | SGK494 | 0.37740839 |
126 | FLT3 | 0.37585879 |
127 | PAK6 | 0.36435307 |
128 | STK10 | 0.36418635 |
129 | IGF1R | 0.35881659 |
130 | SGK3 | 0.35748432 |
131 | TYRO3 | 0.34258166 |
132 | MAP2K6 | 0.33623204 |
133 | CAMK1 | 0.33500901 |
134 | GRK7 | 0.33265473 |
135 | MAPKAPK2 | 0.33245361 |
136 | MAP2K4 | 0.33055848 |
137 | DYRK1B | 0.32887858 |
138 | MAP2K1 | 0.32079078 |
139 | DAPK3 | 0.31597860 |
140 | MAP3K6 | 0.31274810 |
141 | OXSR1 | 0.31172122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.50644374 |
2 | Other glycan degradation_Homo sapiens_hsa00511 | 3.10851747 |
3 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.80758752 |
4 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.54709724 |
5 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.50323462 |
6 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.36635300 |
7 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.24431750 |
8 | PPAR signaling pathway_Homo sapiens_hsa03320 | 2.08041404 |
9 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.06149814 |
10 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.05814910 |
11 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.03933576 |
12 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.92032769 |
13 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.91525408 |
14 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.73836205 |
15 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.67154680 |
16 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.59197709 |
17 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.59158571 |
18 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.53008279 |
19 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.51574811 |
20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.51429198 |
21 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.50751023 |
22 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.50531691 |
23 | Focal adhesion_Homo sapiens_hsa04510 | 1.49392470 |
24 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.48779904 |
25 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.46931258 |
26 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.40904853 |
27 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.36788134 |
28 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.32268381 |
29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.28458543 |
30 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.28389276 |
31 | Bile secretion_Homo sapiens_hsa04976 | 1.26024958 |
32 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.22740699 |
33 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.20813671 |
34 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.20347472 |
35 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.19819987 |
36 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.14838011 |
37 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.09844321 |
38 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.09502210 |
39 | Amoebiasis_Homo sapiens_hsa05146 | 1.09266489 |
40 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.09204290 |
41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.09086646 |
42 | Peroxisome_Homo sapiens_hsa04146 | 1.07916590 |
43 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.07742435 |
44 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.07148251 |
45 | Galactose metabolism_Homo sapiens_hsa00052 | 1.04128713 |
46 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.01337015 |
47 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.00880994 |
48 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.00778208 |
49 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.00646624 |
50 | Adherens junction_Homo sapiens_hsa04520 | 1.00626488 |
51 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.99349510 |
52 | Histidine metabolism_Homo sapiens_hsa00340 | 0.97447909 |
53 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.97415243 |
54 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.97148974 |
55 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.96306035 |
56 | Endocytosis_Homo sapiens_hsa04144 | 0.96242284 |
57 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.94107249 |
58 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.92313970 |
59 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.91266233 |
60 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.91109256 |
61 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.90882641 |
62 | Insulin resistance_Homo sapiens_hsa04931 | 0.88890529 |
63 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.88508542 |
64 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.88231415 |
65 | Lysine degradation_Homo sapiens_hsa00310 | 0.88191124 |
66 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.87787529 |
67 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.86979995 |
68 | Carbon metabolism_Homo sapiens_hsa01200 | 0.85244277 |
69 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.84902350 |
70 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.84761326 |
71 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.83700880 |
72 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.82284492 |
73 | Malaria_Homo sapiens_hsa05144 | 0.81163284 |
74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.80843970 |
75 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.79538830 |
76 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.78240205 |
77 | Melanogenesis_Homo sapiens_hsa04916 | 0.78238621 |
78 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.77410152 |
79 | Tight junction_Homo sapiens_hsa04530 | 0.77083403 |
80 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.76207692 |
81 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.74230584 |
82 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.73368681 |
83 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.73334342 |
84 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.72972818 |
85 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.72127632 |
86 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.72045945 |
87 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.72035664 |
88 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.68969857 |
89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.68078882 |
90 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.66258550 |
91 | Gap junction_Homo sapiens_hsa04540 | 0.65917621 |
92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65724156 |
93 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.64987493 |
94 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.64189530 |
95 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.64131458 |
96 | Glioma_Homo sapiens_hsa05214 | 0.63320700 |
97 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.63222277 |
98 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.62844495 |
99 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.62831924 |
100 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.61932886 |
101 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.60664995 |
102 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.60513083 |
103 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.60345047 |
104 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.60192935 |
105 | Salmonella infection_Homo sapiens_hsa05132 | 0.59964823 |
106 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.59491581 |
107 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.58009899 |
108 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.57188374 |
109 | Renin secretion_Homo sapiens_hsa04924 | 0.56165644 |
110 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.55735528 |
111 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.55546597 |
112 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.54402548 |
113 | Platelet activation_Homo sapiens_hsa04611 | 0.52541606 |
114 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.51987491 |
115 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.51074409 |
116 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.50875693 |
117 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.50759709 |
118 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.50495446 |
119 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.50405543 |
120 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.49831452 |
121 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.49365036 |
122 | Lysosome_Homo sapiens_hsa04142 | 0.48972497 |
123 | Phagosome_Homo sapiens_hsa04145 | 0.48899503 |
124 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.48513188 |
125 | Bladder cancer_Homo sapiens_hsa05219 | 0.47982414 |
126 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.47829959 |
127 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.47569512 |
128 | Viral myocarditis_Homo sapiens_hsa05416 | 0.47159452 |
129 | ABC transporters_Homo sapiens_hsa02010 | 0.47128936 |
130 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.47053352 |
131 | Axon guidance_Homo sapiens_hsa04360 | 0.45483622 |
132 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.45372752 |
133 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.44798249 |
134 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.44724652 |
135 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.44653422 |
136 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.42026298 |
137 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.40427681 |
138 | Prion diseases_Homo sapiens_hsa05020 | 0.39613715 |
139 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.39206923 |
140 | Pertussis_Homo sapiens_hsa05133 | 0.38668991 |
141 | Pathways in cancer_Homo sapiens_hsa05200 | 0.38467840 |
142 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.37922954 |
143 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.37562270 |
144 | Sulfur relay system_Homo sapiens_hsa04122 | 0.34515384 |