SOWAHB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)6.93142323
2omega-hydroxylase P450 pathway (GO:0097267)5.31918467
3intestinal cholesterol absorption (GO:0030299)4.95829025
4desmosome organization (GO:0002934)4.86380803
5intestinal absorption (GO:0050892)4.83974288
6ethanol oxidation (GO:0006069)4.81642037
7drug metabolic process (GO:0017144)4.78102300
8fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.45536064
9phenylpropanoid metabolic process (GO:0009698)4.36790384
10ethanol metabolic process (GO:0006067)4.27439200
11NADH metabolic process (GO:0006734)4.11267206
12regulation of bile acid biosynthetic process (GO:0070857)4.06592458
13glyoxylate metabolic process (GO:0046487)4.05362677
14regulation of fibrinolysis (GO:0051917)4.02479393
15negative regulation of fibrinolysis (GO:0051918)4.01146418
16drug catabolic process (GO:0042737)3.86946012
17fat-soluble vitamin biosynthetic process (GO:0042362)3.82079559
18hormone catabolic process (GO:0042447)3.77995879
19regulation of protein activation cascade (GO:2000257)3.77107480
20tryptophan catabolic process (GO:0006569)3.75344831
21indole-containing compound catabolic process (GO:0042436)3.75344831
22indolalkylamine catabolic process (GO:0046218)3.75344831
23angiotensin maturation (GO:0002003)3.68888186
24complement activation, alternative pathway (GO:0006957)3.64974661
25triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.55825864
26tryptophan metabolic process (GO:0006568)3.53643727
27primary alcohol catabolic process (GO:0034310)3.52639837
28regulation of cholesterol homeostasis (GO:2000188)3.51984329
29bile acid and bile salt transport (GO:0015721)3.51868480
30phospholipid efflux (GO:0033700)3.51688519
31regulation of complement activation (GO:0030449)3.51253121
32pyrimidine-containing compound transmembrane transport (GO:0072531)3.47230544
33positive regulation of lipid catabolic process (GO:0050996)3.42979422
34flavonoid metabolic process (GO:0009812)3.41975178
35regulation of cholesterol esterification (GO:0010872)3.40724406
36aromatic amino acid family catabolic process (GO:0009074)3.39612245
37purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.38804852
383-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.38804852
39renal system process involved in regulation of blood volume (GO:0001977)3.38715350
40cellular ketone body metabolic process (GO:0046950)3.37308428
41glutamine family amino acid biosynthetic process (GO:0009084)3.35432462
42fibrinolysis (GO:0042730)3.32935541
43regulation of cholesterol biosynthetic process (GO:0045540)3.31437482
44vocalization behavior (GO:0071625)3.29406144
45alkaloid metabolic process (GO:0009820)3.28954913
46peptidyl-glutamic acid carboxylation (GO:0017187)3.28403166
47protein carboxylation (GO:0018214)3.28403166
48cellular anion homeostasis (GO:0030002)3.26011509
49regulation of cholesterol metabolic process (GO:0090181)3.25974432
50proline metabolic process (GO:0006560)3.25280312
51multicellular organismal water homeostasis (GO:0050891)3.24005220
52kynurenine metabolic process (GO:0070189)3.20657114
53urea cycle (GO:0000050)3.20237474
54urea metabolic process (GO:0019627)3.20237474
55regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.20201547
56cholesterol efflux (GO:0033344)3.19807516
57alpha-linolenic acid metabolic process (GO:0036109)3.18964347
58heme transport (GO:0015886)3.18736319
59oxidative demethylation (GO:0070989)3.17748486
60cysteine metabolic process (GO:0006534)3.11683531
61high-density lipoprotein particle remodeling (GO:0034375)3.11345837
62sulfate transmembrane transport (GO:1902358)3.10062856
63reverse cholesterol transport (GO:0043691)3.07263466
64L-phenylalanine catabolic process (GO:0006559)3.06760854
65erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.06760854
66synaptic vesicle docking involved in exocytosis (GO:0016081)3.06334238
67renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.05539061
68regulation of triglyceride catabolic process (GO:0010896)3.03031884
69amino-acid betaine metabolic process (GO:0006577)3.02451533
70protein-lipid complex remodeling (GO:0034368)3.02287852
71macromolecular complex remodeling (GO:0034367)3.02287852
72plasma lipoprotein particle remodeling (GO:0034369)3.02287852
73biotin metabolic process (GO:0006768)3.00126914
74drug transmembrane transport (GO:0006855)2.96551582
75regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.94530324
76homocysteine metabolic process (GO:0050667)2.93411544
77proline biosynthetic process (GO:0006561)2.92443259
78cellular biogenic amine catabolic process (GO:0042402)2.90552442
79amine catabolic process (GO:0009310)2.90552442
80exogenous drug catabolic process (GO:0042738)2.89648776
81positive regulation of cellular amine metabolic process (GO:0033240)2.89574837
82nitrogen cycle metabolic process (GO:0071941)2.89496648
83very long-chain fatty acid metabolic process (GO:0000038)2.87818121
84negative regulation of blood coagulation (GO:0030195)2.86852165
85negative regulation of hemostasis (GO:1900047)2.86852165
86regulation of water loss via skin (GO:0033561)2.86151873
87bile acid metabolic process (GO:0008206)2.85247754
88transcytosis (GO:0045056)2.84491123
89ketone body metabolic process (GO:1902224)2.83642573
90phosphate ion transmembrane transport (GO:0035435)2.83319562
91sodium ion homeostasis (GO:0055078)2.82181335
92glutamate secretion (GO:0014047)2.81827106
93L-phenylalanine metabolic process (GO:0006558)2.80724057
94erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.80724057
95oxaloacetate metabolic process (GO:0006107)2.77587393
96negative regulation of hormone biosynthetic process (GO:0032353)2.77165458
97negative regulation of hormone metabolic process (GO:0032351)2.77165458
98indolalkylamine metabolic process (GO:0006586)2.77066660
99very-low-density lipoprotein particle assembly (GO:0034379)2.75697021
100water homeostasis (GO:0030104)2.75592724
101bundle of His cell to Purkinje myocyte communication (GO:0086069)2.75551974
102drinking behavior (GO:0042756)2.75491269
103lipoprotein metabolic process (GO:0042157)2.75324732
104negative regulation of lipase activity (GO:0060192)2.74928489
105lipoprotein transport (GO:0042953)2.74270141
106negative regulation of keratinocyte proliferation (GO:0010839)2.73252310
107citrulline metabolic process (GO:0000052)2.72635511
108bicarbonate transport (GO:0015701)2.72493027
109arginine metabolic process (GO:0006525)2.71519852
110xenobiotic metabolic process (GO:0006805)2.71346763
111citrulline biosynthetic process (GO:0019240)2.70962649
112regulation of fatty acid beta-oxidation (GO:0031998)2.70799655
113plasma lipoprotein particle assembly (GO:0034377)2.70447033
114gap junction assembly (GO:0016264)2.69556889
115fructose metabolic process (GO:0006000)2.69482508
116cytoskeletal anchoring at plasma membrane (GO:0007016)2.69410620
117primary alcohol metabolic process (GO:0034308)2.67398682
118digestive system process (GO:0022600)2.67177842
119transepithelial transport (GO:0070633)2.66436659
120acylglycerol homeostasis (GO:0055090)2.59007473
121triglyceride homeostasis (GO:0070328)2.59007473
122negative regulation of sterol transport (GO:0032372)2.58528066
123negative regulation of cholesterol transport (GO:0032375)2.58528066
124drug transport (GO:0015893)2.58175360
125intestinal epithelial cell development (GO:0060576)2.57969676
126vitamin transmembrane transport (GO:0035461)2.57836461
127calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.57652414
128G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.56320930
129positive regulation of triglyceride lipase activity (GO:0061365)2.55704717
130positive regulation of lipoprotein lipase activity (GO:0051006)2.55704717
131maintenance of gastrointestinal epithelium (GO:0030277)2.55602194
132regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.54051643
133auditory receptor cell stereocilium organization (GO:0060088)2.52794100
134low-density lipoprotein particle remodeling (GO:0034374)2.52598060
135regulation of short-term neuronal synaptic plasticity (GO:0048172)2.51648931
136regulation of guanylate cyclase activity (GO:0031282)2.49825819
137sulfate transport (GO:0008272)2.47472073
138cellular glucuronidation (GO:0052695)2.47383492
139cerebellar granule cell differentiation (GO:0021707)2.46955526
140positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.46632317
141indole-containing compound metabolic process (GO:0042430)2.46598479
142phosphate ion homeostasis (GO:0055062)2.45686260
143trivalent inorganic anion homeostasis (GO:0072506)2.45686260
144glutamate metabolic process (GO:0006536)2.45366969
145cholesterol transport (GO:0030301)2.45072181
146sterol transport (GO:0015918)2.45072181
147sulfur compound transport (GO:0072348)2.44769595
148synaptic vesicle exocytosis (GO:0016079)2.43727807
149bile acid biosynthetic process (GO:0006699)2.42262496
150ionotropic glutamate receptor signaling pathway (GO:0035235)2.41971877
151aromatic amino acid family metabolic process (GO:0009072)2.41337443
152response to histamine (GO:0034776)2.39953320
153sulfur amino acid catabolic process (GO:0000098)2.39901525
154uronic acid metabolic process (GO:0006063)2.39866376
155glucuronate metabolic process (GO:0019585)2.39866376
156synaptic transmission, glutamatergic (GO:0035249)2.39038738
157negative regulation of synaptic transmission, GABAergic (GO:0032229)2.38493973
158response to pheromone (GO:0019236)2.38307669

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR2_21235772_ChIP-Seq_MCF-7_Human3.75582912
2GBX2_23144817_ChIP-Seq_PC3_Human3.14483952
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.04860170
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.95303380
5EZH2_22144423_ChIP-Seq_EOC_Human2.89984776
6ZNF263_19887448_ChIP-Seq_K562_Human2.31305347
7ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.31239486
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.30518589
9RACK7_27058665_Chip-Seq_MCF-7_Human2.28285484
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.24727278
11SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.22352026
12CDX2_20551321_ChIP-Seq_CACO-2_Human2.10177795
13TRIM28_21343339_ChIP-Seq_HEK293_Human2.03905749
14ESR1_15608294_ChIP-ChIP_MCF-7_Human2.03536887
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.02048069
16GATA6_25053715_ChIP-Seq_YYC3_Human2.02024445
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.98369091
18JARID2_20064375_ChIP-Seq_MESCs_Mouse1.94735517
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.93535273
20JARID2_20075857_ChIP-Seq_MESCs_Mouse1.93381324
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.90148915
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.89865058
23EZH2_18974828_ChIP-Seq_MESCs_Mouse1.89154019
24RNF2_18974828_ChIP-Seq_MESCs_Mouse1.89154019
25RXR_22158963_ChIP-Seq_LIVER_Mouse1.88198507
26SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.84690569
27THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.84186302
28EGR1_23403033_ChIP-Seq_LIVER_Mouse1.84112857
29LXR_22292898_ChIP-Seq_THP-1_Human1.82711842
30PIAS1_25552417_ChIP-Seq_VCAP_Human1.82689380
31RUNX1_27514584_Chip-Seq_MCF-7_Human1.82394661
32CDX2_19796622_ChIP-Seq_MESCs_Mouse1.81235857
33TAF15_26573619_Chip-Seq_HEK293_Human1.80077320
34KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.79930824
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.77515483
36LXR_22158963_ChIP-Seq_LIVER_Mouse1.75477094
37SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.70995672
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.70617438
39EZH2_27294783_Chip-Seq_ESCs_Mouse1.69854325
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.69799525
41ZNF217_24962896_ChIP-Seq_MCF-7_Human1.67014783
42MTF2_20144788_ChIP-Seq_MESCs_Mouse1.66598455
43HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.62644331
44KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.62267026
45SUZ12_27294783_Chip-Seq_ESCs_Mouse1.61269950
46FOXA2_19822575_ChIP-Seq_HepG2_Human1.59590668
47FOXO3_23340844_ChIP-Seq_DLD1_Human1.59569715
48DROSHA_22980978_ChIP-Seq_HELA_Human1.59456988
49NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.56588847
50CLOCK_20551151_ChIP-Seq_293T_Human1.56377832
51ZFP57_27257070_Chip-Seq_ESCs_Mouse1.56048392
52VDR_22108803_ChIP-Seq_LS180_Human1.52993819
53FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.52726348
54AR_21909140_ChIP-Seq_LNCAP_Human1.52077826
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.51963479
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.51942907
57AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.51092726
58PPARA_22158963_ChIP-Seq_LIVER_Mouse1.50513456
59HIF1A_21447827_ChIP-Seq_MCF-7_Human1.47186079
60RNF2_27304074_Chip-Seq_ESCs_Mouse1.46742268
61GATA3_24758297_ChIP-Seq_MCF-7_Human1.46524975
62REST_21632747_ChIP-Seq_MESCs_Mouse1.46263145
63P300_19829295_ChIP-Seq_ESCs_Human1.46197610
64ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.45715059
65SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.45628734
66FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.44370464
67AR_21572438_ChIP-Seq_LNCaP_Human1.43727369
68SMAD4_21799915_ChIP-Seq_A2780_Human1.40815107
69EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40509127
70ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.39812931
71PPAR_26484153_Chip-Seq_NCI-H1993_Human1.39570610
72CBX2_27304074_Chip-Seq_ESCs_Mouse1.39301771
73IKZF1_21737484_ChIP-ChIP_HCT116_Human1.37583841
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.37386771
75CREB1_26743006_Chip-Seq_LNCaP_Human1.36338389
76CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.35341724
77P63_26484246_Chip-Seq_KERATINOCYTES_Human1.33916203
78TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.33382390
79POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31436066
80AHR_22903824_ChIP-Seq_MCF-7_Human1.30422401
81ARNT_22903824_ChIP-Seq_MCF-7_Human1.29644830
82KLF5_25053715_ChIP-Seq_YYC3_Human1.28623909
83HNF4A_19822575_ChIP-Seq_HepG2_Human1.27202919
84TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25706809
85FOXA1_25552417_ChIP-Seq_VCAP_Human1.24195685
86NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.23416888
87PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.22185846
88AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21873427
89TP63_17297297_ChIP-ChIP_HaCaT_Human1.21609589
90SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.21020293
91PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.20436345
92TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18465760
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.18038350
94RXR_22108803_ChIP-Seq_LS180_Human1.17409090
95KDM2B_26808549_Chip-Seq_K562_Human1.17086019
96ERG_21242973_ChIP-ChIP_JURKAT_Human1.16242778
97SOX2_20726797_ChIP-Seq_SW620_Human1.15995806
98TOP2B_26459242_ChIP-Seq_MCF-7_Human1.15025646
99SOX2_27498859_Chip-Seq_STOMACH_Mouse1.15018394
100ESR1_21235772_ChIP-Seq_MCF-7_Human1.15013782
101SMAD3_21741376_ChIP-Seq_HESCs_Human1.14524788
102MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14183903
103ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.13598990
104SMAD_19615063_ChIP-ChIP_OVARY_Human1.13421499
105FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.12728250
106AR_25329375_ChIP-Seq_VCAP_Human1.12397784
107SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12307535
108ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.11287893
109ATF3_27146783_Chip-Seq_COLON_Human1.10665528
110CTBP1_25329375_ChIP-Seq_LNCAP_Human1.10305065
111GATA4_25053715_ChIP-Seq_YYC3_Human1.10099132
112RNF2_27304074_Chip-Seq_NSC_Mouse1.09291041
113EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.08941897
114RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.08910802
115P53_22387025_ChIP-Seq_ESCs_Mouse1.08668388
116NANOG_18555785_Chip-Seq_ESCs_Mouse1.08645729
117TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.08594769
118SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.08267810
119SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.08267810
120TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07599055
121E2F1_18555785_Chip-Seq_ESCs_Mouse1.06845040
122BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.06515198
123UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06096222
124TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06095112
125NFE2_27457419_Chip-Seq_LIVER_Mouse1.05178541
126PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.05138891
127SOX9_24532713_ChIP-Seq_HFSC_Mouse1.05098810
128PCGF2_27294783_Chip-Seq_ESCs_Mouse1.04897227
129SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04318448
130FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03919815
131SMC4_20622854_ChIP-Seq_HELA_Human1.03196895
132ESR1_20079471_ChIP-ChIP_T-47D_Human1.02874950
133CHD1_26751641_Chip-Seq_LNCaP_Human1.02621840
134NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.02446741
135TP53_18474530_ChIP-ChIP_U2OS_Human1.02430996
136POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02092852
137TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02092852
138STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.01950928
139SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00717448
140DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99835541
141CTCF_27219007_Chip-Seq_Bcells_Human0.99389893
142STAT3_23295773_ChIP-Seq_U87_Human0.98296663
143CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.97931337
144SOX2_18555785_Chip-Seq_ESCs_Mouse0.97580877
145SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96825654
146OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96606342
147SOX2_21211035_ChIP-Seq_LN229_Gbm0.96172069
148TCF4_18268006_ChIP-ChIP_LS174T_Human0.95956100
149CMYC_18555785_Chip-Seq_ESCs_Mouse0.95722354
150SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.95707932
151EZH2_27294783_Chip-Seq_NPCs_Mouse0.95668220
152RUNX1_27457419_Chip-Seq_LIVER_Mouse0.95417582
153STAT3_18555785_Chip-Seq_ESCs_Mouse0.94603155
154BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94546338
155REST_18959480_ChIP-ChIP_MESCs_Mouse0.94016156
156FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.93772794
157P53_22127205_ChIP-Seq_FIBROBLAST_Human0.92382944
158P300_18555785_Chip-Seq_ESCs_Mouse0.92014888
159RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.91836230
160ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91148285
161ZFP281_18757296_ChIP-ChIP_E14_Mouse0.91113209
162P300_27058665_Chip-Seq_ZR-75-30cells_Human0.89255763
163ELK3_25401928_ChIP-Seq_HUVEC_Human0.89008588
164UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.88304575
165TCF7_22412390_ChIP-Seq_EML_Mouse0.86651421
166TET1_21451524_ChIP-Seq_MESCs_Mouse0.86407494
167TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.84826729
168ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.84724628
169EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.84518443
170JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.84233875
171TP63_22573176_ChIP-Seq_HFKS_Human0.84181635
172KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.83138476
173SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82895849
174CTNNB1_20460455_ChIP-Seq_HCT116_Human0.82046965
175WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.80307664
176KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80003661

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis5.71177630
2MP0002139_abnormal_hepatobiliary_system4.43253864
3MP0005085_abnormal_gallbladder_physiolo3.92467251
4MP0001666_abnormal_nutrient_absorption3.31470862
5MP0005365_abnormal_bile_salt3.12175205
6MP0008875_abnormal_xenobiotic_pharmacok2.97805843
7MP0004019_abnormal_vitamin_homeostasis2.78757877
8MP0003252_abnormal_bile_duct2.41580488
9MP0002876_abnormal_thyroid_physiology2.36619064
10MP0003879_abnormal_hair_cell2.34622992
11MP0000566_synostosis2.32559312
12MP0010234_abnormal_vibrissa_follicle2.25033353
13MP0010329_abnormal_lipoprotein_level2.10905742
14MP0004043_abnormal_pH_regulation2.07296680
15MP0003705_abnormal_hypodermis_morpholog1.95172849
16MP0003880_abnormal_central_pattern1.93878044
17MP0003183_abnormal_peptide_metabolism1.90175269
18MP0004264_abnormal_extraembryonic_tissu1.87641373
19MP0005377_hearing/vestibular/ear_phenot1.83195391
20MP0003878_abnormal_ear_physiology1.83195391
21MP0004859_abnormal_synaptic_plasticity1.82293391
22MP0009780_abnormal_chondrocyte_physiolo1.78813235
23MP0004885_abnormal_endolymph1.77692989
24MP0001664_abnormal_digestion1.67949342
25MP0010678_abnormal_skin_adnexa1.66867105
26MP0003195_calcinosis1.66798821
27MP0000462_abnormal_digestive_system1.66405254
28MP0001968_abnormal_touch/_nociception1.64981401
29MP0005409_darkened_coat_color1.62440176
30MP0003868_abnormal_feces_composition1.61924597
31MP0002736_abnormal_nociception_after1.61166737
32MP0002822_catalepsy1.59096905
33MP0005451_abnormal_body_composition1.57394478
34MP0009046_muscle_twitch1.53923630
35MP0005646_abnormal_pituitary_gland1.52785578
36MP0004742_abnormal_vestibular_system1.52240145
37MP0005501_abnormal_skin_physiology1.51234824
38MP0005645_abnormal_hypothalamus_physiol1.49611693
39MP0002138_abnormal_hepatobiliary_system1.48540594
40MP0000538_abnormal_urinary_bladder1.46838608
41MP0002277_abnormal_respiratory_mucosa1.46205329
42MP0001486_abnormal_startle_reflex1.46062368
43MP0003635_abnormal_synaptic_transmissio1.45308709
44MP0005084_abnormal_gallbladder_morpholo1.44467190
45MP0008004_abnormal_stomach_pH1.44447879
46MP0009745_abnormal_behavioral_response1.42783742
47MP0005332_abnormal_amino_acid1.39906787
48MP0005083_abnormal_biliary_tract1.39170783
49MP0001440_abnormal_grooming_behavior1.34214205
50MP0002572_abnormal_emotion/affect_behav1.33482241
51MP0004270_analgesia1.27956217
52MP0005248_abnormal_Harderian_gland1.26278216
53MP0010386_abnormal_urinary_bladder1.25852783
54MP0010352_gastrointestinal_tract_polyps1.25304694
55MP0004782_abnormal_surfactant_physiolog1.24441973
56MP0000467_abnormal_esophagus_morphology1.24408517
57MP0004858_abnormal_nervous_system1.24380847
58MP0002064_seizures1.23450196
59MP0009697_abnormal_copulation1.22674046
60MP0000609_abnormal_liver_physiology1.22553762
61MP0002063_abnormal_learning/memory/cond1.22414064
62MP0001765_abnormal_ion_homeostasis1.22207491
63MP0001501_abnormal_sleep_pattern1.22139727
64MP0005670_abnormal_white_adipose1.21591774
65MP0001881_abnormal_mammary_gland1.20858558
66MP0002249_abnormal_larynx_morphology1.20678045
67MP0003453_abnormal_keratinocyte_physiol1.19669701
68MP0002272_abnormal_nervous_system1.19581670
69MP0002734_abnormal_mechanical_nocicepti1.18148934
70MP0002557_abnormal_social/conspecific_i1.14203847
71MP0003123_paternal_imprinting1.12457235
72MP0001485_abnormal_pinna_reflex1.11600899
73MP0004147_increased_porphyrin_level1.11595309
74MP0000377_abnormal_hair_follicle1.09023940
75MP0000383_abnormal_hair_follicle1.08612698
76MP0001963_abnormal_hearing_physiology1.08159503
77MP0002909_abnormal_adrenal_gland1.07944911
78MP0005636_abnormal_mineral_homeostasis1.06082762
79MP0002254_reproductive_system_inflammat1.04587892
80MP0006292_abnormal_olfactory_placode1.04109822
81MP0003866_abnormal_defecation1.03428142
82MP0005666_abnormal_adipose_tissue1.03228044
83MP0001188_hyperpigmentation1.01423764
84MP0002067_abnormal_sensory_capabilities1.00788349
85MP0002098_abnormal_vibrissa_morphology1.00525526
86MP0005381_digestive/alimentary_phenotyp0.99776790
87MP0001663_abnormal_digestive_system0.99633919
88MP0002118_abnormal_lipid_homeostasis0.99052142
89MP0000627_abnormal_mammary_gland0.99008333
90MP0001216_abnormal_epidermal_layer0.98593240
91MP0002735_abnormal_chemical_nociception0.96847105
92MP0001177_atelectasis0.94780340
93MP0003938_abnormal_ear_development0.94670079
94MP0005076_abnormal_cell_differentiation0.94346681
95MP0009643_abnormal_urine_homeostasis0.94228556
96MP0008872_abnormal_physiological_respon0.93208642
97MP0000678_abnormal_parathyroid_gland0.92654963
98MP0000579_abnormal_nail_morphology0.92441728
99MP0003806_abnormal_nucleotide_metabolis0.91979614
100MP0004185_abnormal_adipocyte_glucose0.91300409
101MP0000026_abnormal_inner_ear0.91070048
102MP0003329_amyloid_beta_deposits0.90454591
103MP0002796_impaired_skin_barrier0.89739488
104MP0001764_abnormal_homeostasis0.88540440
105MP0009840_abnormal_foam_cell0.88073259
106MP0000537_abnormal_urethra_morphology0.86034761
107MP0001502_abnormal_circadian_rhythm0.85482557
108MP0001346_abnormal_lacrimal_gland0.85350822
109MP0005058_abnormal_lysosome_morphology0.83048496
110MP0000477_abnormal_intestine_morphology0.82910599
111MP0001849_ear_inflammation0.82255465
112MP0002089_abnormal_postnatal_growth/wei0.81354820
113MP0000516_abnormal_urinary_system0.81267450
114MP0005367_renal/urinary_system_phenotyp0.81267450
115MP0003191_abnormal_cellular_cholesterol0.80738629
116MP0001984_abnormal_olfaction0.80568285
117MP0004924_abnormal_behavior0.80482440
118MP0005386_behavior/neurological_phenoty0.80482440
119MP0010155_abnormal_intestine_physiology0.78924902
120MP0005166_decreased_susceptibility_to0.77653773
121MP0005551_abnormal_eye_electrophysiolog0.75731157
122MP0003566_abnormal_cell_adhesion0.74717465
123MP0002136_abnormal_kidney_physiology0.73163529
124MP0008569_lethality_at_weaning0.72978342
125MP0009053_abnormal_anal_canal0.72334306
126MP0005319_abnormal_enzyme/_coenzyme0.71565900
127MP0001756_abnormal_urination0.69854456
128MP0001873_stomach_inflammation0.69486566
129MP0002971_abnormal_brown_adipose0.68948006
130MP0010771_integument_phenotype0.67421529
131MP0003941_abnormal_skin_development0.67395417
132MP0005448_abnormal_energy_balance0.67165612
133MP0001970_abnormal_pain_threshold0.66957832
134MP0003638_abnormal_response/metabolism_0.66393569
135MP0002733_abnormal_thermal_nociception0.65793130
136MP0002009_preneoplasia0.64242388
137MP0005584_abnormal_enzyme/coenzyme_acti0.63650332
138MP0002184_abnormal_innervation0.63614624
139MP0005310_abnormal_salivary_gland0.63613108
140MP0003718_maternal_effect0.63181548
141MP0000604_amyloidosis0.61178673
142MP0004947_skin_inflammation0.60243071
143MP0000762_abnormal_tongue_morphology0.59352812
144MP0005408_hypopigmentation0.59283343
145MP0002896_abnormal_bone_mineralization0.58751202
146MP0009642_abnormal_blood_homeostasis0.55472763
147MP0005375_adipose_tissue_phenotype0.54039903
148MP0009379_abnormal_foot_pigmentation0.50598237
149MP0000598_abnormal_liver_morphology0.50113311
150MP0009931_abnormal_skin_appearance0.49887986
151MP0003315_abnormal_perineum_morphology0.49319327
152MP0002078_abnormal_glucose_homeostasis0.48031730

Predicted human phenotypes

RankGene SetZ-score
1Conjugated hyperbilirubinemia (HP:0002908)6.33001091
2Focal motor seizures (HP:0011153)4.72405865
3Abnormality of glutamine family amino acid metabolism (HP:0010902)4.57476767
4Complement deficiency (HP:0004431)4.15104002
5Hyperactive renin-angiotensin system (HP:0000841)4.07208966
6Metabolic alkalosis (HP:0200114)3.84939941
7Intrahepatic cholestasis (HP:0001406)3.84006488
8Febrile seizures (HP:0002373)3.72655871
9Flat acetabular roof (HP:0003180)3.62750969
10Hypobetalipoproteinemia (HP:0003563)3.60507262
11Ileus (HP:0002595)3.57404017
12Abnormality of complement system (HP:0005339)3.53239860
13Hyperventilation (HP:0002883)3.40052839
14Pili torti (HP:0003777)3.31505120
15Hemorrhage of the eye (HP:0011885)3.29651307
16Abnormality of chloride homeostasis (HP:0011422)3.27578311
17Widely patent fontanelles and sutures (HP:0004492)3.20234307
18Abnormality of monocarboxylic acid metabolism (HP:0010996)3.18106691
19Fat malabsorption (HP:0002630)3.13469266
20Prolonged partial thromboplastin time (HP:0003645)3.10132235
21Abnormality of purine metabolism (HP:0004352)3.06366626
22Hyperammonemia (HP:0001987)3.06234780
23Acanthocytosis (HP:0001927)3.05844565
24Systemic lupus erythematosus (HP:0002725)3.03653256
25Alkalosis (HP:0001948)3.01028711
26Congenital sensorineural hearing impairment (HP:0008527)2.99708229
27Steatorrhea (HP:0002570)2.90704271
28Abnormality of aromatic amino acid family metabolism (HP:0004338)2.88974740
29Hydroxyprolinuria (HP:0003080)2.87597519
30Abnormality of proline metabolism (HP:0010907)2.87597519
31Epileptic encephalopathy (HP:0200134)2.84686714
32Glomerulonephritis (HP:0000099)2.83209001
33Gout (HP:0001997)2.80131934
34Abnormal hair laboratory examination (HP:0003328)2.76167306
35Thin bony cortex (HP:0002753)2.75111019
36Abnormality of aspartate family amino acid metabolism (HP:0010899)2.73012782
37Right ventricular cardiomyopathy (HP:0011663)2.64793663
38Confusion (HP:0001289)2.64160971
39Hyperaldosteronism (HP:0000859)2.63443814
40Abnormality of nucleobase metabolism (HP:0010932)2.62041765
41Abnormality of urine glucose concentration (HP:0011016)2.60626386
42Glycosuria (HP:0003076)2.60626386
43Hypokalemic alkalosis (HP:0001949)2.60604610
44Abnormality of renin-angiotensin system (HP:0000847)2.58672756
45Symptomatic seizures (HP:0011145)2.57723609
46Focal segmental glomerulosclerosis (HP:0000097)2.55751856
47Progressive cerebellar ataxia (HP:0002073)2.55340162
48Nephritis (HP:0000123)2.55084614
49Hyperglycinuria (HP:0003108)2.54257173
50Alopecia of scalp (HP:0002293)2.54136538
51Pustule (HP:0200039)2.53947243
52Vascular calcification (HP:0004934)2.49615355
53Atonic seizures (HP:0010819)2.45371261
54Xanthomatosis (HP:0000991)2.44894665
55Onycholysis (HP:0001806)2.44570215
56Abnormality of renal excretion (HP:0011036)2.44557281
57Spontaneous abortion (HP:0005268)2.42075173
58Hyperlipoproteinemia (HP:0010980)2.36682608
59Abnormality of sulfur amino acid metabolism (HP:0004339)2.36572906
60Abnormality of pyrimidine metabolism (HP:0004353)2.35267430
61Hypolipoproteinemia (HP:0010981)2.34974816
62Absence seizures (HP:0002121)2.34591951
63Abnormality of the gastric mucosa (HP:0004295)2.34004884
64Hyperphosphaturia (HP:0003109)2.32299269
65Dehydration (HP:0001944)2.32079473
66Metabolic acidosis (HP:0001942)2.31107790
67Focal seizures (HP:0007359)2.30678092
68Fair hair (HP:0002286)2.27558933
69Abnormal urine phosphate concentration (HP:0012599)2.27246883
70Epidermoid cyst (HP:0200040)2.26894831
71Joint hemorrhage (HP:0005261)2.26646250
72Malnutrition (HP:0004395)2.24874684
73Abnormal tarsal ossification (HP:0008369)2.23417346
74Bifid scrotum (HP:0000048)2.22658121
75Abnormality of the vitamin B12 metabolism (HP:0004341)2.21046142
76Increased purine levels (HP:0004368)2.20504114
77Hyperuricemia (HP:0002149)2.20504114
78Decreased circulating renin level (HP:0003351)2.17422685
79Abnormality of vitamin B metabolism (HP:0004340)2.15685295
80Hypoglycemic seizures (HP:0002173)2.15380962
81Hypophosphatemic rickets (HP:0004912)2.15244729
82Increased circulating renin level (HP:0000848)2.14571049
83Abnormality of the common coagulation pathway (HP:0010990)2.13963514
84Abnormal urine output (HP:0012590)2.13789275
85Rickets (HP:0002748)2.11858688
86Glomerulosclerosis (HP:0000096)2.11026367
87Abnormality of vitamin metabolism (HP:0100508)2.10571836
88Hyperparathyroidism (HP:0000843)2.09160598
89Proximal tubulopathy (HP:0000114)2.09157779
90Deep venous thrombosis (HP:0002625)2.08098985
91Osteomalacia (HP:0002749)2.07859506
92J-shaped sella turcica (HP:0002680)2.07330230
93Dialeptic seizures (HP:0011146)2.02500079
94Ketoacidosis (HP:0001993)2.00453747
95Hypercholesterolemia (HP:0003124)2.00384046
96Alveolar cell carcinoma (HP:0006519)1.99875547
97Germ cell neoplasia (HP:0100728)1.98816426
98Lip pit (HP:0100267)1.98158909
99Myokymia (HP:0002411)1.97299173
100Hyperbilirubinemia (HP:0002904)1.97048551
101Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.95870584
102Generalized hypopigmentation of hair (HP:0011358)1.95603672
103Cheilitis (HP:0100825)1.95453635
104Nephrolithiasis (HP:0000787)1.95347586
105Renal salt wasting (HP:0000127)1.95150201
106Visceral angiomatosis (HP:0100761)1.95097436
107Abdominal distention (HP:0003270)1.94116355
108Elevated alkaline phosphatase (HP:0003155)1.93289501
109Bronchomalacia (HP:0002780)1.92420808
110Cardiovascular calcification (HP:0011915)1.92156702
111Progressive sensorineural hearing impairment (HP:0000408)1.91734458
112Abnormality of alkaline phosphatase activity (HP:0004379)1.90919836
113Neonatal death (HP:0003811)1.90916005
114Hyperphosphatemia (HP:0002905)1.90869430
115Septate vagina (HP:0001153)1.89879647
116Ankle clonus (HP:0011448)1.89728238
117Abnormality of carpal bone ossification (HP:0006257)1.89692066
118Chronic diarrhea (HP:0002028)1.89656492
119Abnormal enzyme/coenzyme activity (HP:0012379)1.89276854
120Status epilepticus (HP:0002133)1.88112741
121Hypomagnesemia (HP:0002917)1.87798216
122Wide cranial sutures (HP:0010537)1.86891893
123Hypotension (HP:0002615)1.84884268
124Renal tubular acidosis (HP:0001947)1.84177514
125Neonatal hypoglycemia (HP:0001998)1.83917875
126Abnormality of the distal phalanx of the thumb (HP:0009617)1.83514585
127Neoplasm of the tracheobronchial system (HP:0100552)1.83129666
128Cholecystitis (HP:0001082)1.82907952
129Abnormal gallbladder physiology (HP:0012438)1.82907952
130Hypophosphatemia (HP:0002148)1.82743598
131Curly hair (HP:0002212)1.82661167
132Abnormality of serine family amino acid metabolism (HP:0010894)1.81723505
133Abnormality of glycine metabolism (HP:0010895)1.81723505
134Syncope (HP:0001279)1.81151878
135Amelogenesis imperfecta (HP:0000705)1.81064779
136Chronic hepatic failure (HP:0100626)1.80939664
137Facial shape deformation (HP:0011334)1.80265408
138Potter facies (HP:0002009)1.80265408
139Renal tubular dysfunction (HP:0000124)1.79462662
140Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.79105640
141Hemangiomatosis (HP:0007461)1.78733887
142Ketosis (HP:0001946)1.78183006
143Generalized tonic-clonic seizures (HP:0002069)1.77112500
144Lethargy (HP:0001254)1.76313508
145Abnormality of the Achilles tendon (HP:0005109)1.76041992
146Polyuria (HP:0000103)1.75258268
147Bone pain (HP:0002653)1.73848117
148Growth hormone excess (HP:0000845)1.73268292
149Abnormality of the intrinsic pathway (HP:0010989)1.72212349
150Neonatal onset (HP:0003623)1.71911667
151Delayed CNS myelination (HP:0002188)1.71737493

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.09332063
2EPHA23.43132159
3CASK3.42824104
4FRK3.37727180
5OXSR13.02648199
6DAPK22.99683397
7EPHA42.95300459
8PKN22.92466003
9MAP3K122.91268534
10PRKD32.87736969
11MST42.85378259
12AKT32.61313290
13MAP2K72.45678914
14LMTK22.25222657
15MST1R2.24885821
16ERN12.13222506
17NTRK32.06373800
18NUAK12.04762879
19PIK3CA2.00472335
20CDK191.99574655
21MET1.86968368
22SMG11.81897340
23LATS11.65968164
24IRAK31.62687438
25NME11.62129448
26MAP3K41.60996097
27ICK1.58092220
28INSRR1.55375017
29PRKG21.55320601
30TNIK1.54210548
31FGFR41.49551855
32MAP2K41.44320345
33SCYL21.42449024
34EEF2K1.40370718
35ACVR1B1.35633497
36SGK21.33555954
37MAP3K21.32537637
38BMPR21.32441492
39WNK31.29144274
40TESK11.27358626
41SGK4941.27337846
42SGK2231.27337846
43SIK31.27061384
44ERBB41.24254585
45MAPKAPK31.20356919
46DAPK11.14510338
47RIPK41.12910959
48LATS21.11109240
49RPS6KB21.10964979
50CAMK2B1.08363478
51CAMK1D1.03605828
52RIPK11.01788730
53TAOK11.01474215
54EPHB20.98016578
55STK38L0.97090294
56PAK40.96144195
57CAMK2G0.96060192
58STK390.93799444
59MAP2K20.93015791
60MAP3K30.92934247
61RET0.91910897
62SGK30.91371504
63CAMK2D0.90999246
64BMPR1B0.90896001
65PTK20.89907076
66MAP2K60.88414398
67ARAF0.86572221
68CDK30.86129247
69WNK40.84852033
70MAP3K140.82894124
71PRKCG0.79980141
72PDK10.79601251
73CAMKK20.79041487
74RPS6KA20.78936400
75PRKD20.76544000
76CAMK10.76173660
77GRK50.75854352
78CCNB10.75677220
79CAMK2A0.74944760
80FER0.74732503
81PRKCI0.74641364
82TESK20.74116317
83PTK60.71942977
84STK110.71900109
85MAP3K90.71191860
86TAOK30.68518144
87PRKCE0.68473529
88YES10.67966954
89TNK20.67554776
90CAMKK10.67128091
91CDK120.66489067
92MAP3K70.64562008
93ERBB20.64063997
94SGK10.63654391
95MTOR0.63291151
96MAPK130.62829452
97GRK10.62711890
98PDGFRA0.62273597
99KSR20.61765673
100GRK60.59533843
101NEK60.59305826
102NTRK20.58769784
103PRKAA20.58182146
104FGFR30.57814917
105PRKCA0.57018722
106CSNK1A10.56342396
107SIK10.55913688
108PRPF4B0.54600767
109NTRK10.53977631
110ADRBK20.53489701
111CAMK40.52603947
112CDK50.51969075
113MAP3K100.50769916
114MAP2K10.49853981
115MAP3K110.49773880
116PRKCZ0.49150236
117MAP3K10.48922462
118BCR0.48642280
119PAK60.48625676
120PLK20.48046938
121STK380.47107529
122PIM20.46985765
123CAMK1G0.46616276
124STK240.45674993
125RPS6KB10.45564954
126SIK20.45218898
127MAP3K130.44799341
128FGR0.44624325
129KSR10.43883054
130MAPKAPK50.43413071
131EPHB10.42951912
132TAOK20.42861710
133MYLK0.42743415
134PRKACA0.41695260
135IRAK20.40589852
136PRKG10.40052522
137WNK10.39547221
138MARK20.35899966
139PDPK10.34879910
140LRRK20.34736090
141PRKACG0.34611832
142MAPK70.34228096
143EIF2AK10.33817679
144PNCK0.32067319
145AKT20.29595751
146MINK10.28828339
147PRKCH0.27960963
148MUSK0.27035072
149DYRK1B0.26271548
150ILK0.23957710
151MAPK110.23752590
152SRC0.22001442
153CHUK0.21877917
154PRKAA10.21733339
155RPS6KC10.20945068

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009202.56909342
2Fat digestion and absorption_Homo sapiens_hsa049752.55445629
3Vitamin digestion and absorption_Homo sapiens_hsa049772.32891377
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.28905750
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.28306398
6Mineral absorption_Homo sapiens_hsa049782.28157606
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.15997307
8Arginine biosynthesis_Homo sapiens_hsa002202.14080123
9Histidine metabolism_Homo sapiens_hsa003402.07593496
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.98784885
11Bile secretion_Homo sapiens_hsa049761.98090545
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.90504517
13Nitrogen metabolism_Homo sapiens_hsa009101.86641427
14Nicotine addiction_Homo sapiens_hsa050331.84063160
15Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.83887620
16Tryptophan metabolism_Homo sapiens_hsa003801.79740735
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.74353988
18Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.69150427
19Folate biosynthesis_Homo sapiens_hsa007901.64323522
20Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.64308476
21Caffeine metabolism_Homo sapiens_hsa002321.62491023
22Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.58087310
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.54414960
24Butanoate metabolism_Homo sapiens_hsa006501.49208748
25Starch and sucrose metabolism_Homo sapiens_hsa005001.47305246
26Synaptic vesicle cycle_Homo sapiens_hsa047211.45533995
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.44166539
28Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.35890130
29Galactose metabolism_Homo sapiens_hsa000521.33251999
30Pentose and glucuronate interconversions_Homo sapiens_hsa000401.30549662
31Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.22845548
32Steroid hormone biosynthesis_Homo sapiens_hsa001401.21283178
33Peroxisome_Homo sapiens_hsa041461.20994469
34PPAR signaling pathway_Homo sapiens_hsa033201.19635147
35beta-Alanine metabolism_Homo sapiens_hsa004101.19379862
36Vitamin B6 metabolism_Homo sapiens_hsa007501.16735686
37Collecting duct acid secretion_Homo sapiens_hsa049661.15576814
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.14685125
39Phenylalanine metabolism_Homo sapiens_hsa003601.14278053
40Taste transduction_Homo sapiens_hsa047421.14256332
41Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.13650636
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.12598672
43Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.11344384
44Fatty acid degradation_Homo sapiens_hsa000711.10977122
45Retinol metabolism_Homo sapiens_hsa008301.09582874
46Salivary secretion_Homo sapiens_hsa049701.09182998
47Renin-angiotensin system_Homo sapiens_hsa046141.07838020
48Fructose and mannose metabolism_Homo sapiens_hsa000511.07388418
49Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07221648
50Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.06747529
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.06504130
52Insulin secretion_Homo sapiens_hsa049111.04283819
53Chemical carcinogenesis_Homo sapiens_hsa052041.03631343
54Glutamatergic synapse_Homo sapiens_hsa047241.01150957
55ABC transporters_Homo sapiens_hsa020101.01026757
56Arginine and proline metabolism_Homo sapiens_hsa003300.96823046
57Biosynthesis of amino acids_Homo sapiens_hsa012300.95110598
58Fatty acid biosynthesis_Homo sapiens_hsa000610.94706659
59Complement and coagulation cascades_Homo sapiens_hsa046100.93492969
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.92135895
61GABAergic synapse_Homo sapiens_hsa047270.85948177
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.85259040
63Carbon metabolism_Homo sapiens_hsa012000.84606589
64Pyruvate metabolism_Homo sapiens_hsa006200.82795514
65Sulfur relay system_Homo sapiens_hsa041220.82289882
66Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.82001009
67Gastric acid secretion_Homo sapiens_hsa049710.78820999
68Pancreatic secretion_Homo sapiens_hsa049720.77003401
69Prion diseases_Homo sapiens_hsa050200.76883152
70Glycerolipid metabolism_Homo sapiens_hsa005610.75078071
71Protein digestion and absorption_Homo sapiens_hsa049740.73144143
72Propanoate metabolism_Homo sapiens_hsa006400.72893392
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71838874
74Circadian entrainment_Homo sapiens_hsa047130.71279684
75Tyrosine metabolism_Homo sapiens_hsa003500.70973704
76Vibrio cholerae infection_Homo sapiens_hsa051100.70870421
77Sphingolipid metabolism_Homo sapiens_hsa006000.70729013
78Amphetamine addiction_Homo sapiens_hsa050310.70654343
79Morphine addiction_Homo sapiens_hsa050320.69056986
80Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.69005113
81Fatty acid metabolism_Homo sapiens_hsa012120.65221979
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.65145193
83Olfactory transduction_Homo sapiens_hsa047400.64362258
84Oxidative phosphorylation_Homo sapiens_hsa001900.64233895
85Thyroid hormone synthesis_Homo sapiens_hsa049180.64197755
86Steroid biosynthesis_Homo sapiens_hsa001000.62193155
87alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.61790303
88Serotonergic synapse_Homo sapiens_hsa047260.61056269
89Glutathione metabolism_Homo sapiens_hsa004800.60660975
90Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.59543750
91Long-term potentiation_Homo sapiens_hsa047200.59346724
92Insulin resistance_Homo sapiens_hsa049310.58599635
93Pentose phosphate pathway_Homo sapiens_hsa000300.58187274
94African trypanosomiasis_Homo sapiens_hsa051430.56444917
95Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.54824301
96Long-term depression_Homo sapiens_hsa047300.54801418
97Drug metabolism - other enzymes_Homo sapiens_hsa009830.53382742
98Fatty acid elongation_Homo sapiens_hsa000620.52024342
99AMPK signaling pathway_Homo sapiens_hsa041520.47929291
100Cysteine and methionine metabolism_Homo sapiens_hsa002700.47704249
101Arachidonic acid metabolism_Homo sapiens_hsa005900.47037088
102Tight junction_Homo sapiens_hsa045300.45543140
103Linoleic acid metabolism_Homo sapiens_hsa005910.44634146
104Glucagon signaling pathway_Homo sapiens_hsa049220.42623038
105Alzheimers disease_Homo sapiens_hsa050100.42544258
106Metabolic pathways_Homo sapiens_hsa011000.40863538
107Selenocompound metabolism_Homo sapiens_hsa004500.40554482
1082-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40468723
109Type II diabetes mellitus_Homo sapiens_hsa049300.40113635
110Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.39657957
111Ether lipid metabolism_Homo sapiens_hsa005650.38714081
112Renin secretion_Homo sapiens_hsa049240.37824765
113Other glycan degradation_Homo sapiens_hsa005110.35968337
114Insulin signaling pathway_Homo sapiens_hsa049100.32075478
115Lysine degradation_Homo sapiens_hsa003100.29750289
116Thyroid cancer_Homo sapiens_hsa052160.28490027
117Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.27761695
118Glycerophospholipid metabolism_Homo sapiens_hsa005640.27708606
119Adipocytokine signaling pathway_Homo sapiens_hsa049200.25834111
120Hepatitis C_Homo sapiens_hsa051600.25199725
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.22022322
122Choline metabolism in cancer_Homo sapiens_hsa052310.21982244
123Endometrial cancer_Homo sapiens_hsa052130.18898508
124Central carbon metabolism in cancer_Homo sapiens_hsa052300.17733978
125Inositol phosphate metabolism_Homo sapiens_hsa005620.17664760
126Thyroid hormone signaling pathway_Homo sapiens_hsa049190.12814192
127ErbB signaling pathway_Homo sapiens_hsa040120.11865687
128Aldosterone synthesis and secretion_Homo sapiens_hsa049250.11657319
129Amoebiasis_Homo sapiens_hsa051460.10496006

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