SP110

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.49679147
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.49679147
3antigen processing and presentation of endogenous antigen (GO:0019883)5.45184139
4positive regulation of gamma-delta T cell activation (GO:0046645)4.86706040
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.21773647
6macrophage activation involved in immune response (GO:0002281)4.10009143
7negative regulation of T cell mediated immunity (GO:0002710)3.99009147
8detection of other organism (GO:0098543)3.94526903
9cellular response to type I interferon (GO:0071357)3.84744765
10type I interferon signaling pathway (GO:0060337)3.84744765
11response to type I interferon (GO:0034340)3.83588076
12detection of bacterium (GO:0016045)3.81041295
13regulation of B cell receptor signaling pathway (GO:0050855)3.76763557
14negative regulation of lymphocyte mediated immunity (GO:0002707)3.76023508
15positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.72012651
16immunoglobulin mediated immune response (GO:0016064)3.66325659
17NIK/NF-kappaB signaling (GO:0038061)3.64920829
18regulation of RIG-I signaling pathway (GO:0039535)3.62122338
19negative thymic T cell selection (GO:0045060)3.58430354
20detection of molecule of bacterial origin (GO:0032490)3.54836665
21negative T cell selection (GO:0043383)3.54203557
22microglial cell activation (GO:0001774)3.53716662
23detection of external biotic stimulus (GO:0098581)3.52797775
24regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.52397161
25response to host immune response (GO:0052572)3.50280732
26response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.50280732
27cellular extravasation (GO:0045123)3.47424884
28regulation of T cell tolerance induction (GO:0002664)3.46651616
29T cell migration (GO:0072678)3.44432675
30positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.43804785
31interferon-gamma-mediated signaling pathway (GO:0060333)3.43762715
32positive T cell selection (GO:0043368)3.42443945
33regulation of regulatory T cell differentiation (GO:0045589)3.38397260
34regulation of T cell mediated cytotoxicity (GO:0001914)3.38017275
35negative regulation of leukocyte mediated immunity (GO:0002704)3.37693601
36regulation of gamma-delta T cell activation (GO:0046643)3.37490809
37regulation of gamma-delta T cell differentiation (GO:0045586)3.36727231
38cellular response to interferon-beta (GO:0035458)3.35443186
39regulation of alpha-beta T cell proliferation (GO:0046640)3.33304347
40myeloid cell activation involved in immune response (GO:0002275)3.28076334
41positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.27405722
42positive regulation of T cell mediated cytotoxicity (GO:0001916)3.26382690
43positive regulation of interferon-alpha production (GO:0032727)3.26082410
44regulation of tolerance induction (GO:0002643)3.24712732
45positive regulation of antigen processing and presentation (GO:0002579)3.21772916
46defense response to protozoan (GO:0042832)3.21554955
47positive regulation of B cell differentiation (GO:0045579)3.19026709
48tolerance induction (GO:0002507)3.17272283
49regulation of B cell differentiation (GO:0045577)3.17147268
50response to host (GO:0075136)3.16425202
51response to host defenses (GO:0052200)3.16425202
52response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.16425202
53negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.14602520
54leukocyte aggregation (GO:0070486)3.14600629
55regulation of interleukin-12 biosynthetic process (GO:0045075)3.12168226
56activated T cell proliferation (GO:0050798)3.11921680
57positive regulation of alpha-beta T cell proliferation (GO:0046641)3.11079852
58detection of biotic stimulus (GO:0009595)3.10906425
59B cell receptor signaling pathway (GO:0050853)3.09482003
60cellular response to exogenous dsRNA (GO:0071360)3.09249492
61regulation of type I interferon-mediated signaling pathway (GO:0060338)3.08173002
62regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.07840933
63regulation of interferon-alpha production (GO:0032647)3.07793410
64regulation of response to interferon-gamma (GO:0060330)3.05119324
65positive thymic T cell selection (GO:0045059)3.04847448
66antigen processing and presentation via MHC class Ib (GO:0002475)3.03237655
67B cell mediated immunity (GO:0019724)3.02337428
68myeloid dendritic cell activation (GO:0001773)3.02285556
69positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.01795862
70cellular response to zinc ion (GO:0071294)3.01205145
71macrophage activation (GO:0042116)2.97714355
72negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.97384745
73negative regulation of T-helper cell differentiation (GO:0045623)2.97384745
74response to protozoan (GO:0001562)2.97131671
75production of molecular mediator involved in inflammatory response (GO:0002532)2.96586151
76regulation of natural killer cell mediated immunity (GO:0002715)2.94476858
77regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.94476858
78interferon-gamma secretion (GO:0072643)2.94208638
79regulation of antigen processing and presentation (GO:0002577)2.93254180
80positive regulation of tolerance induction (GO:0002645)2.92868839
81negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.92862557
82regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.92572041
83Arp2/3 complex-mediated actin nucleation (GO:0034314)2.92353470
84response to interferon-beta (GO:0035456)2.91926285
85antigen receptor-mediated signaling pathway (GO:0050851)2.90796181
86regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.89824583
87regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.88766166
88positive regulation of interferon-beta production (GO:0032728)2.86349243
89ribosomal small subunit assembly (GO:0000028)2.86279169
90response to interleukin-15 (GO:0070672)2.85690737
91response to peptidoglycan (GO:0032494)2.85482093
92neutrophil activation involved in immune response (GO:0002283)2.84834474
93interferon-gamma production (GO:0032609)2.84288740
94thymic T cell selection (GO:0045061)2.81749482
95natural killer cell mediated cytotoxicity (GO:0042267)2.81680232
96natural killer cell mediated immunity (GO:0002228)2.81680232
97myeloid dendritic cell differentiation (GO:0043011)2.77308359
98mast cell activation (GO:0045576)2.77034797
99regulation of T cell receptor signaling pathway (GO:0050856)2.75497592
100positive regulation of humoral immune response (GO:0002922)2.72316091
101positive regulation of interleukin-2 production (GO:0032743)2.72014303
102cellular response to interleukin-15 (GO:0071350)2.71918975
103regulation of interferon-beta biosynthetic process (GO:0045357)2.70623704
104T cell selection (GO:0045058)2.70341246
105respiratory burst (GO:0045730)2.68987892
106positive regulation of isotype switching (GO:0045830)2.68787600
107regulation of T-helper 1 cell differentiation (GO:0045625)2.68520664
108positive regulation by symbiont of host defense response (GO:0052509)2.66444033
109modulation by symbiont of host defense response (GO:0052031)2.66444033
110modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.66444033
111modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.66444033
112positive regulation by organism of defense response of other organism involved in symbiotic interact2.66444033
113modulation by symbiont of host immune response (GO:0052553)2.66444033
114negative regulation of viral genome replication (GO:0045071)2.65625603
115neutrophil activation (GO:0042119)2.63060754
116positive regulation of defense response to virus by host (GO:0002230)2.62497973
117response to interferon-alpha (GO:0035455)2.60506548
118positive regulation of interleukin-12 production (GO:0032735)2.56891459
119response to muramyl dipeptide (GO:0032495)2.56289147
120positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.56247161
121mature B cell differentiation (GO:0002335)2.55733353
122T cell costimulation (GO:0031295)2.55666886
123natural killer cell activation (GO:0030101)2.54060399
124cellular response to interferon-gamma (GO:0071346)2.53569787
125lymphocyte costimulation (GO:0031294)2.51535030
126regulation of dendritic cell antigen processing and presentation (GO:0002604)2.51009193
127granulocyte activation (GO:0036230)2.50388426
128regulation of interleukin-2 biosynthetic process (GO:0045076)2.48183423
129negative regulation of cell killing (GO:0031342)2.46799215
130negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.46799215
131negative regulation of interleukin-12 production (GO:0032695)2.43348780
132negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.42971105
133positive regulation of B cell mediated immunity (GO:0002714)2.42790045
134positive regulation of immunoglobulin mediated immune response (GO:0002891)2.42790045
135DNA replication checkpoint (GO:0000076)2.42195764
136chaperone mediated protein folding requiring cofactor (GO:0051085)2.41959951
137T cell homeostasis (GO:0043029)2.39668472

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.82193242
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.05435534
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.41825250
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.13038410
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.53934030
6* IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.42483037
7SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.02148787
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.02076714
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.01635469
10SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.55902965
11IRF8_27001747_Chip-Seq_BMDM_Mouse2.54938154
12BP1_19119308_ChIP-ChIP_Hs578T_Human2.52497313
13STAT4_19710469_ChIP-ChIP_TH1__Mouse2.50955229
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.50253080
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.36822624
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.32659611
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.32516357
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.28690257
19* SPI1_23547873_ChIP-Seq_NB4_Human2.28075805
20SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.27434072
21MYC_22102868_ChIP-Seq_BL_Human2.23778945
22NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.17890884
23MYB_26560356_Chip-Seq_TH2_Human2.16874308
24E2F4_17652178_ChIP-ChIP_JURKAT_Human2.10611150
25FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.04519499
26NOTCH1_21737748_ChIP-Seq_TLL_Human2.04095861
27SCL_19346495_ChIP-Seq_HPC-7_Human2.01980049
28FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.01249744
29* SMAD_19615063_ChIP-ChIP_OVARY_Human2.00427537
30MYB_26560356_Chip-Seq_TH1_Human1.98285043
31ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.96260508
32VDR_21846776_ChIP-Seq_THP-1_Human1.93252385
33MAF_26560356_Chip-Seq_TH1_Human1.90409305
34RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.88775754
35ELF1_17652178_ChIP-ChIP_JURKAT_Human1.87901253
36FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.82913168
37VDR_24787735_ChIP-Seq_THP-1_Human1.81879979
38SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.74014443
39VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73863102
40* VDR_23849224_ChIP-Seq_CD4+_Human1.72884900
41EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.71322866
42GABP_17652178_ChIP-ChIP_JURKAT_Human1.65629808
43RUNX1_22412390_ChIP-Seq_EML_Mouse1.63044803
44RUNX_20019798_ChIP-Seq_JUKART_Human1.56255122
45UTX_26944678_Chip-Seq_JUKART_Human1.55561391
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.55091422
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.53671760
48MYC_18555785_ChIP-Seq_MESCs_Mouse1.53605966
49MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.51041438
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.50251044
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.49055382
52VDR_24763502_ChIP-Seq_THP-1_Human1.49008622
53FOXP3_21729870_ChIP-Seq_TREG_Human1.47794980
54CIITA_25753668_ChIP-Seq_RAJI_Human1.43903856
55JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.42579755
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.40635913
57RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.38441529
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.36804897
59NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.35753474
60ETS1_20019798_ChIP-Seq_JURKAT_Human1.35132691
61PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.34371252
62* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.31947182
63MAF_26560356_Chip-Seq_TH2_Human1.30768816
64GATA3_27048872_Chip-Seq_THYMUS_Human1.29417607
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.29215396
66E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.28404126
67KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.27933865
68VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.27123565
69CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.21848733
70CREB1_15753290_ChIP-ChIP_HEK293T_Human1.21545950
71STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.19473641
72* GATA1_19941827_ChIP-Seq_MEL_Mouse1.19024072
73GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.18615815
74LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.17664705
75MYC_18358816_ChIP-ChIP_MESCs_Mouse1.16895946
76PU_27001747_Chip-Seq_BMDM_Mouse1.16506510
77CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.16323048
78GATA1_22025678_ChIP-Seq_K562_Human1.15218783
79NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.14921500
80PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12474283
81NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.10940130
82MYC_19079543_ChIP-ChIP_MESCs_Mouse1.10631146
83* SPI1_23127762_ChIP-Seq_K562_Human1.10523784
84CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10191576
85MYC_19030024_ChIP-ChIP_MESCs_Mouse1.09379049
86SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.08949288
87GATA3_26560356_Chip-Seq_TH2_Human1.08740548
88ELK1_19687146_ChIP-ChIP_HELA_Human1.08561011
89RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08549953
90GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07699064
91PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05974460
92GATA2_21666600_ChIP-Seq_HMVEC_Human1.05725772
93NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.04566486
94TCF7_22412390_ChIP-Seq_EML_Mouse1.04504292
95MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.03770776
96XRN2_22483619_ChIP-Seq_HELA_Human1.02210550
97LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.02195300
98GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00294348
99* SMRT_27268052_Chip-Seq_Bcells_Human0.98939247
100GABP_19822575_ChIP-Seq_HepG2_Human0.98858887
101SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98225253
102SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97580573
103GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.96683758
104KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.95250120
105TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94712158
106KDM5A_27292631_Chip-Seq_BREAST_Human0.93965355
107CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93740482
108PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93630592
109Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.93541319
110NELFA_20434984_ChIP-Seq_ESCs_Mouse0.93143563
111CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90015570
112SRF_21415370_ChIP-Seq_HL-1_Mouse0.89304824
113GATA1_19941826_ChIP-Seq_K562_Human0.89051017
114KDM2B_26808549_Chip-Seq_SUP-B15_Human0.88405144
115DCP1A_22483619_ChIP-Seq_HELA_Human0.87925994
116BCL6_27268052_Chip-Seq_Bcells_Human0.87284872
117PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87040506
118* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86314066
119GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85272365
120KDM2B_26808549_Chip-Seq_DND41_Human0.83737849
121STAT6_21828071_ChIP-Seq_BEAS2B_Human0.80587779
122RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.77559928
123GATA3_26560356_Chip-Seq_TH1_Human0.76794717
124FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.76461294
125STAT1_20625510_ChIP-Seq_HELA_Human0.76141928
126GATA2_19941826_ChIP-Seq_K562_Human0.75719361
127* EGR1_23403033_ChIP-Seq_LIVER_Mouse0.75663568
128STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.72052613
129SPI1_20517297_ChIP-Seq_HL60_Human0.71780832
130KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.70949286
131TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.70085001
132P300_27268052_Chip-Seq_Bcells_Human0.69911183
133BCOR_27268052_Chip-Seq_Bcells_Human0.65164669
134BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.64720423

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.73823748
2MP0005671_abnormal_response_to3.52351752
3MP0000685_abnormal_immune_system3.33218755
4MP0009785_altered_susceptibility_to3.14290558
5MP0001800_abnormal_humoral_immune3.10709173
6MP0005387_immune_system_phenotype2.96977991
7MP0001790_abnormal_immune_system2.96977991
8MP0002396_abnormal_hematopoietic_system2.88168696
9MP0005000_abnormal_immune_tolerance2.87113552
10MP0003763_abnormal_thymus_physiology2.86414692
11MP0002452_abnormal_antigen_presenting2.76311723
12MP0002723_abnormal_immune_serum2.69771049
13MP0002148_abnormal_hypersensitivity_rea2.67427046
14MP0005025_abnormal_response_to2.66229779
15MP0001819_abnormal_immune_cell2.58048842
16MP0002420_abnormal_adaptive_immunity2.57544299
17MP0003436_decreased_susceptibility_to2.56202340
18MP0003693_abnormal_embryo_hatching2.52142802
19MP0002398_abnormal_bone_marrow2.46367194
20MP0002166_altered_tumor_susceptibility2.37181838
21MP0008057_abnormal_DNA_replication2.34645332
22MP0002419_abnormal_innate_immunity2.34268020
23MP0009333_abnormal_splenocyte_physiolog2.24186855
24MP0000716_abnormal_immune_system2.22773088
25MP0002006_tumorigenesis2.18513949
26MP0006082_CNS_inflammation2.14180529
27MP0003724_increased_susceptibility_to2.05706173
28MP0000689_abnormal_spleen_morphology2.02646916
29MP0002405_respiratory_system_inflammati1.96593935
30MP0002722_abnormal_immune_system1.94449034
31MP0004808_abnormal_hematopoietic_stem1.91859806
32MP0010094_abnormal_chromosome_stability1.89703104
33MP0001545_abnormal_hematopoietic_system1.88532925
34MP0005397_hematopoietic_system_phenotyp1.88532925
35MP0002429_abnormal_blood_cell1.88089159
36MP0003303_peritoneal_inflammation1.82189415
37MP0005464_abnormal_platelet_physiology1.81260199
38MP0010155_abnormal_intestine_physiology1.79744164
39MP0003111_abnormal_nucleus_morphology1.76674945
40MP0001853_heart_inflammation1.75835472
41MP0003077_abnormal_cell_cycle1.72846074
42MP0001845_abnormal_inflammatory_respons1.65481536
43MP0000703_abnormal_thymus_morphology1.63561108
44MP0005310_abnormal_salivary_gland1.62809556
45MP0004947_skin_inflammation1.62334016
46MP0001873_stomach_inflammation1.61404730
47MP0004510_myositis1.56960701
48MP0000490_abnormal_crypts_of1.50960957
49MP0008058_abnormal_DNA_repair1.50715211
50MP0009278_abnormal_bone_marrow1.37067986
51MP0010307_abnormal_tumor_latency1.30194048
52MP0008007_abnormal_cellular_replicative1.29727340
53MP0008469_abnormal_protein_level1.27659436
54MP0004957_abnormal_blastocyst_morpholog1.25839864
55MP0000465_gastrointestinal_hemorrhage1.24016769
56MP0002019_abnormal_tumor_incidence1.20405319
57MP0000858_altered_metastatic_potential1.20346644
58MP0003866_abnormal_defecation1.20051302
59MP0005174_abnormal_tail_pigmentation1.16274854
60MP0003448_altered_tumor_morphology1.16018247
61MP0001533_abnormal_skeleton_physiology1.12387228
62MP0004883_abnormal_blood_vessel1.12049308
63MP0008260_abnormal_autophagy1.11621859
64MP0003045_fibrosis1.05583577
65MP0005075_abnormal_melanosome_morpholog1.04694469
66MP0009764_decreased_sensitivity_to1.01184240
67MP0002163_abnormal_gland_morphology0.95556287
68MP0002132_abnormal_respiratory_system0.95413090
69MP0005166_decreased_susceptibility_to0.95291232
70MP0005451_abnormal_body_composition0.95136156
71MP0005058_abnormal_lysosome_morphology0.94642049
72MP0003075_altered_response_to0.92692072
73MP0005164_abnormal_response_to0.90956247
74MP0002933_joint_inflammation0.88713030
75MP0002095_abnormal_skin_pigmentation0.87452448
76MP0000015_abnormal_ear_pigmentation0.85326410
77MP0001663_abnormal_digestive_system0.83734535
78MP0000313_abnormal_cell_death0.80605589
79MP0003300_gastrointestinal_ulcer0.75982945
80MP0000350_abnormal_cell_proliferation0.73995194
81MP0009765_abnormal_xenobiotic_induced0.73929036
82MP0005390_skeleton_phenotype0.71307294
83MP0008004_abnormal_stomach_pH0.71213881
84MP0003786_premature_aging0.71012723
85MP0009763_increased_sensitivity_to0.70716642
86MP0000343_altered_response_to0.70515495
87MP0002138_abnormal_hepatobiliary_system0.70311346
88MP0003806_abnormal_nucleotide_metabolis0.66599875
89MP0002277_abnormal_respiratory_mucosa0.65813001
90MP0008877_abnormal_DNA_methylation0.65776495
91MP0003690_abnormal_glial_cell0.65378933
92MP0009840_abnormal_foam_cell0.65322574
93MP0003195_calcinosis0.64859276
94MP0003191_abnormal_cellular_cholesterol0.64281383
95MP0003183_abnormal_peptide_metabolism0.63680943
96MP0000249_abnormal_blood_vessel0.62931638
97MP0002693_abnormal_pancreas_physiology0.62645366
98MP0002332_abnormal_exercise_endurance0.62547448
99MP0000604_amyloidosis0.62334473
100MP0001851_eye_inflammation0.62248251
101MP0002009_preneoplasia0.61652062
102MP0003718_maternal_effect0.59826582
103MP0003172_abnormal_lysosome_physiology0.59566216
104MP0001986_abnormal_taste_sensitivity0.58665713
105MP0000371_diluted_coat_color0.58400096
106MP0003828_pulmonary_edema0.58214995
107MP0003795_abnormal_bone_structure0.56637970
108MP0004381_abnormal_hair_follicle0.55810369
109MP0003646_muscle_fatigue0.55493011
110MP0010352_gastrointestinal_tract_polyps0.54907253
111MP0003787_abnormal_imprinting0.54644450
112MP0005621_abnormal_cell_physiology0.53630311
113MP0002998_abnormal_bone_remodeling0.53584254
114MP0003943_abnormal_hepatobiliary_system0.52828668
115MP0008874_decreased_physiological_sensi0.51812441
116MP0004782_abnormal_surfactant_physiolog0.50177519
117MP0005076_abnormal_cell_differentiation0.50027600
118MP0000569_abnormal_digit_pigmentation0.49556053
119MP0002136_abnormal_kidney_physiology0.48788779
120MP0003656_abnormal_erythrocyte_physiolo0.48354601
121MP0003252_abnormal_bile_duct0.48348021
122MP0004130_abnormal_muscle_cell0.46175977

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)4.72129361
2Chronic otitis media (HP:0000389)4.57572494
3Eczematoid dermatitis (HP:0000976)4.53531310
4Elevated erythrocyte sedimentation rate (HP:0003565)4.50128002
5Recurrent bacterial skin infections (HP:0005406)4.38750512
6Recurrent viral infections (HP:0004429)4.32852880
7Recurrent fungal infections (HP:0002841)4.21610172
8IgM deficiency (HP:0002850)4.19278551
9Myositis (HP:0100614)4.18763309
10Recurrent bronchitis (HP:0002837)4.15917061
11Abnormal delayed hypersensitivity skin test (HP:0002963)3.78146908
12Panhypogammaglobulinemia (HP:0003139)3.68106718
13Recurrent cutaneous fungal infections (HP:0011370)3.67418413
14Chronic mucocutaneous candidiasis (HP:0002728)3.67418413
15Agammaglobulinemia (HP:0004432)3.59621267
16Autoimmune thrombocytopenia (HP:0001973)3.57737215
17Thrombocytosis (HP:0001894)3.55817844
18Vasculitis (HP:0002633)3.53174499
19Abnormality of T cells (HP:0002843)3.52337735
20Pustule (HP:0200039)3.52265554
21Abnormality of T cell number (HP:0011839)3.50232001
22Meningitis (HP:0001287)3.45578550
23Obstructive lung disease (HP:0006536)3.44237983
24Chronic obstructive pulmonary disease (HP:0006510)3.44237983
25Mediastinal lymphadenopathy (HP:0100721)3.43850780
26Abnormality of T cell physiology (HP:0011840)3.38697615
27T lymphocytopenia (HP:0005403)3.38636457
28Retrobulbar optic neuritis (HP:0100654)3.33137683
29Optic neuritis (HP:0100653)3.33137683
30Recurrent skin infections (HP:0001581)3.31749092
31* IgG deficiency (HP:0004315)3.14665533
32Orchitis (HP:0100796)3.11593314
33Lymphopenia (HP:0001888)3.08457075
34Nasal polyposis (HP:0100582)3.07538717
35Abnormality of cells of the lymphoid lineage (HP:0012140)3.04393942
36Cellulitis (HP:0100658)3.01831770
37Abnormality of macrophages (HP:0004311)2.94986585
38Abnormality of the fingertips (HP:0001211)2.94421733
39Eosinophilia (HP:0001880)2.87623372
40Urticaria (HP:0001025)2.87180960
41Encephalitis (HP:0002383)2.85576508
42IgA deficiency (HP:0002720)2.85521075
43B lymphocytopenia (HP:0010976)2.83913521
44Abnormality of B cell number (HP:0010975)2.83913521
45Abnormality of the prostate (HP:0008775)2.80788164
46Thyroiditis (HP:0100646)2.80243240
47Abnormality of eosinophils (HP:0001879)2.75779889
48Anorexia (HP:0002039)2.74210278
49Abnormality of the nasal mucosa (HP:0000433)2.71178619
50Lymphoma (HP:0002665)2.69853995
51Pulmonary embolism (HP:0002204)2.69352317
52Recurrent gram-negative bacterial infections (HP:0005420)2.69183554
53Recurrent sinusitis (HP:0011108)2.68406873
54Petechiae (HP:0000967)2.68149022
55Gastrointestinal stroma tumor (HP:0100723)2.67767406
56Increased IgM level (HP:0003496)2.67741395
57Leukocytosis (HP:0001974)2.67461181
58Gingival bleeding (HP:0000225)2.67439788
59Granulocytopenia (HP:0001913)2.66597278
60Gangrene (HP:0100758)2.66431246
61Inflammation of the large intestine (HP:0002037)2.64159157
62Increased IgE level (HP:0003212)2.62521371
63Abnormality of the pleura (HP:0002103)2.62115347
64Severe combined immunodeficiency (HP:0004430)2.60994136
65Hypergammaglobulinemia (HP:0010702)2.60224455
66Pulmonary infiltrates (HP:0002113)2.59447763
67Basal ganglia calcification (HP:0002135)2.58065496
68Stomatitis (HP:0010280)2.58055872
69Gastrointestinal inflammation (HP:0004386)2.57235514
70Combined immunodeficiency (HP:0005387)2.57211171
71Birth length less than 3rd percentile (HP:0003561)2.56107060
72Chronic sinusitis (HP:0011109)2.55862895
73Gastrointestinal infarctions (HP:0005244)2.54901821
74Colitis (HP:0002583)2.53426524
75Prostate neoplasm (HP:0100787)2.53118164
76Hypochromic anemia (HP:0001931)2.48940630
77Autoimmune hemolytic anemia (HP:0001890)2.46382305
78Recurrent pneumonia (HP:0006532)2.44161345
79Hemoptysis (HP:0002105)2.44110267
80Emphysema (HP:0002097)2.44096325
81Chronic diarrhea (HP:0002028)2.42826354
82Hypochromic microcytic anemia (HP:0004840)2.41769379
83Chromsome breakage (HP:0040012)2.40934901
84Recurrent lower respiratory tract infections (HP:0002783)2.39911574
85Bronchitis (HP:0012387)2.34362811
86Acute myeloid leukemia (HP:0004808)2.29849643
87Joint swelling (HP:0001386)2.29438141
88Periodontitis (HP:0000704)2.28992591
89Arterial thrombosis (HP:0004420)2.26539012
90Keratoconjunctivitis sicca (HP:0001097)2.25502499
91Chromosomal breakage induced by crosslinking agents (HP:0003221)2.25210930
92Keratitis (HP:0000491)2.24692023
93Episodic fever (HP:0001954)2.24651713
94Sepsis (HP:0100806)2.23398239
95Verrucae (HP:0200043)2.22386417
96Papilloma (HP:0012740)2.22386417
97Gingivitis (HP:0000230)2.18308191
98Leukopenia (HP:0001882)2.17448513
99Spontaneous hematomas (HP:0007420)2.17048005
100Entropion (HP:0000621)2.15093236
101Interstitial pulmonary disease (HP:0006530)2.13282717
102Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.12260795
103Skin rash (HP:0000988)2.10515067
104Prolonged bleeding time (HP:0003010)2.10060542
105Stomach cancer (HP:0012126)2.09026089
106Glomerulopathy (HP:0100820)2.08606509
107Keratoconjunctivitis (HP:0001096)2.08312144
108Hematochezia (HP:0002573)2.07805250
109Skin ulcer (HP:0200042)2.07427237
110Amaurosis fugax (HP:0100576)2.07025421
111Neutropenia (HP:0001875)2.03894783
112Polyneuropathy (HP:0001271)2.03555141
113Osteomyelitis (HP:0002754)2.03428685
114Peritonitis (HP:0002586)2.03283219
115Vertigo (HP:0002321)2.02436790
116Myelodysplasia (HP:0002863)2.02197331
117Microcytic anemia (HP:0001935)2.02047230
118Clubbing of toes (HP:0100760)2.01814597
119Aplastic anemia (HP:0001915)2.00330245
120Epistaxis (HP:0000421)2.00240098
121Chest pain (HP:0100749)1.96973482
122Cheilitis (HP:0100825)1.96052398
123Restrictive lung disease (HP:0002091)1.95836950
124Abnormality of the pericardium (HP:0001697)1.94521719
125Abnormality of the peritoneum (HP:0002585)1.93857221

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.78260224
2TXK3.12434433
3TYK22.99024135
4JAK32.80919404
5IRAK42.78764053
6MAP3K142.71717707
7KIT2.70686430
8IKBKE2.67812083
9BLK2.64418342
10TBK12.40389644
11ZAP702.15933318
12IKBKB2.03490779
13NME22.02165045
14IRAK31.99281459
15TEC1.87315374
16JAK11.86047351
17BTK1.84993551
18TNK21.83573612
19SYK1.82190531
20CSF1R1.71428723
21RIPK41.66280948
22STK101.65518203
23BUB11.58632401
24WEE11.57691902
25PIM11.55745382
26NEK21.54252847
27FGFR41.53856596
28MAP3K131.52838465
29PIM21.52396888
30ACVR1B1.52015500
31PLK41.44394197
32RPS6KA41.40663217
33ITK1.33575126
34LCK1.29486701
35FGR1.26503032
36CHUK1.22602731
37NLK1.21323124
38TAOK31.21046610
39LYN1.16130029
40EPHB11.15861126
41PRPF4B1.14426551
42CSK1.13800538
43HCK1.13394358
44MARK31.11897811
45EEF2K1.09697505
46GRK61.06290313
47STK41.06139734
48EIF2AK11.06133124
49CDC71.04398040
50FGFR31.04330570
51STK161.03256097
52IRAK11.03056467
53EIF2AK31.01690625
54BRSK21.01465986
55GRK71.01205895
56MAP3K30.99452174
57EIF2AK20.98874361
58FRK0.97686817
59SRPK10.94939285
60CLK10.92149186
61CDK40.91932729
62MAP3K110.89966109
63PIK3CG0.86785426
64FES0.86124309
65HIPK20.84013064
66MAP3K10.83649830
67MAP2K30.81212255
68MST40.80647703
69ATR0.79300042
70TAOK10.76216253
71FLT30.74848412
72NEK90.74414627
73PDK10.72213981
74LRRK20.70823012
75TESK20.70658942
76NUAK10.64854570
77VRK10.63969607
78PTK2B0.63961914
79DYRK30.63331874
80KDR0.63075769
81JAK20.62838348
82AURKB0.62566327
83PRKD20.62547173
84TSSK60.62359406
85CCNB10.62353973
86EPHA30.61647471
87PLK10.59899570
88STK30.59127049
89FYN0.59006109
90MAP2K60.58731822
91CAMKK20.58101298
92TGFBR20.55980822
93STK240.54591642
94CDC42BPA0.54127314
95MKNK20.53232248
96MAPK70.52932419
97MAP3K80.52536389
98TGFBR10.51459827
99YES10.51243811
100TLK10.50673512
101IRAK20.50493880
102MAPK110.48611281
103BMPR20.48557297
104PRKCQ0.47488648
105TAOK20.47103120
106RAF10.45413764
107RPS6KA50.44814059
108BRSK10.44424091
109MATK0.44331084
110CDK70.42665848
111ABL10.42539306
112MKNK10.41912875
113MAPK120.38760462
114ERN10.38649351
115MAP2K20.38247267
116CHEK10.37292153
117CDK120.37156303
118MAPKAPK20.37049320
119ALK0.37040137
120MAP3K50.36682212
121ADRBK20.35990351
122CHEK20.35960509
123MARK20.35394617
124ZAK0.34747846
125SIK20.34249214
126MAP3K100.33543267
127TRPM70.33529161
128SIK30.33318713
129PDPK10.33258223
130RPS6KB20.33204279
131GRK50.32744592
132PRKCD0.30544131
133STK110.30527991
134EGFR0.30118074
135SGK20.28216758
136SGK30.26364002
137IGF1R0.24953730
138MAP3K70.24508890
139ADRBK10.22050809
140MAPK30.21094250
141PRKCH0.20973062

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.45573690
2Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.79492506
3Intestinal immune network for IgA production_Homo sapiens_hsa046722.71276561
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.51646397
5Allograft rejection_Homo sapiens_hsa053302.51374726
6Graft-versus-host disease_Homo sapiens_hsa053322.48287168
7Measles_Homo sapiens_hsa051622.38540614
8DNA replication_Homo sapiens_hsa030302.30508347
9Leishmaniasis_Homo sapiens_hsa051402.22733230
10Antigen processing and presentation_Homo sapiens_hsa046122.20076103
11Herpes simplex infection_Homo sapiens_hsa051682.11326739
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.04541211
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.03352341
14Base excision repair_Homo sapiens_hsa034101.91464956
15B cell receptor signaling pathway_Homo sapiens_hsa046621.88705669
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.83280156
17Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.78406497
18RNA polymerase_Homo sapiens_hsa030201.76892016
19NOD-like receptor signaling pathway_Homo sapiens_hsa046211.76542093
20Homologous recombination_Homo sapiens_hsa034401.76374570
21Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.74907455
22Mismatch repair_Homo sapiens_hsa034301.73175163
23Hematopoietic cell lineage_Homo sapiens_hsa046401.72736577
24Influenza A_Homo sapiens_hsa051641.66072726
25Osteoclast differentiation_Homo sapiens_hsa043801.63605285
26Jak-STAT signaling pathway_Homo sapiens_hsa046301.53004580
27T cell receptor signaling pathway_Homo sapiens_hsa046601.46483754
28Autoimmune thyroid disease_Homo sapiens_hsa053201.42023677
29Ribosome_Homo sapiens_hsa030101.39232750
30Legionellosis_Homo sapiens_hsa051341.37508125
31Proteasome_Homo sapiens_hsa030501.33558251
32Non-homologous end-joining_Homo sapiens_hsa034501.30419391
33Cell cycle_Homo sapiens_hsa041101.27819127
34Epstein-Barr virus infection_Homo sapiens_hsa051691.25472207
35Type I diabetes mellitus_Homo sapiens_hsa049401.23443866
36p53 signaling pathway_Homo sapiens_hsa041151.23041173
37Spliceosome_Homo sapiens_hsa030401.22365154
38Pyrimidine metabolism_Homo sapiens_hsa002401.20415939
39TNF signaling pathway_Homo sapiens_hsa046681.19549629
40Tuberculosis_Homo sapiens_hsa051521.18468691
41Hepatitis B_Homo sapiens_hsa051611.17794879
42Apoptosis_Homo sapiens_hsa042101.17160529
43Nucleotide excision repair_Homo sapiens_hsa034201.16547790
44RNA transport_Homo sapiens_hsa030131.16141837
45Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.15429924
46Toxoplasmosis_Homo sapiens_hsa051451.15389969
47Vitamin B6 metabolism_Homo sapiens_hsa007501.14538622
48Pertussis_Homo sapiens_hsa051331.13429371
49Fanconi anemia pathway_Homo sapiens_hsa034601.11841958
50Viral myocarditis_Homo sapiens_hsa054161.10615757
51Chemokine signaling pathway_Homo sapiens_hsa040621.10180093
52Asthma_Homo sapiens_hsa053101.08674144
53Malaria_Homo sapiens_hsa051441.06570519
54Shigellosis_Homo sapiens_hsa051311.06008956
55Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.04944195
56Basal transcription factors_Homo sapiens_hsa030221.04596647
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99870280
58Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.98374181
59Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93201965
60Staphylococcus aureus infection_Homo sapiens_hsa051500.92551730
61RNA degradation_Homo sapiens_hsa030180.90316652
62Acute myeloid leukemia_Homo sapiens_hsa052210.87034617
63Rheumatoid arthritis_Homo sapiens_hsa053230.84912632
64Hepatitis C_Homo sapiens_hsa051600.84068696
65Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79540706
66Viral carcinogenesis_Homo sapiens_hsa052030.77705962
67African trypanosomiasis_Homo sapiens_hsa051430.74090812
68Other glycan degradation_Homo sapiens_hsa005110.74090581
69Salmonella infection_Homo sapiens_hsa051320.72924776
70Leukocyte transendothelial migration_Homo sapiens_hsa046700.72885332
71HTLV-I infection_Homo sapiens_hsa051660.70556269
72Pentose phosphate pathway_Homo sapiens_hsa000300.66279513
73One carbon pool by folate_Homo sapiens_hsa006700.63114935
74Pancreatic cancer_Homo sapiens_hsa052120.62762055
75Small cell lung cancer_Homo sapiens_hsa052220.62276750
76Purine metabolism_Homo sapiens_hsa002300.58413430
77Chronic myeloid leukemia_Homo sapiens_hsa052200.57922685
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.57749064
79Platelet activation_Homo sapiens_hsa046110.57578222
80Dorso-ventral axis formation_Homo sapiens_hsa043200.55482491
81Lysosome_Homo sapiens_hsa041420.55155597
82Prolactin signaling pathway_Homo sapiens_hsa049170.55002019
83Regulation of autophagy_Homo sapiens_hsa041400.51812939
84AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.51163655
85VEGF signaling pathway_Homo sapiens_hsa043700.50422332
86Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47058519
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.46300317
88Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.44124376
89mRNA surveillance pathway_Homo sapiens_hsa030150.43998743
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.42982436
91Sphingolipid signaling pathway_Homo sapiens_hsa040710.42408540
92Glycosaminoglycan degradation_Homo sapiens_hsa005310.41700549
93Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40933833
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36688764
95Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33961143
96Endocytosis_Homo sapiens_hsa041440.33606637
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.32391430
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31778931
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.31209422
100Non-small cell lung cancer_Homo sapiens_hsa052230.29206092
101Insulin resistance_Homo sapiens_hsa049310.28661179
102Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.28626048
103FoxO signaling pathway_Homo sapiens_hsa040680.28524798
104Notch signaling pathway_Homo sapiens_hsa043300.28297324
105MicroRNAs in cancer_Homo sapiens_hsa052060.27012341
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.26998928
107Inositol phosphate metabolism_Homo sapiens_hsa005620.25970435
108HIF-1 signaling pathway_Homo sapiens_hsa040660.25505725
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25205815
110MAPK signaling pathway_Homo sapiens_hsa040100.25126353
111Phosphatidylinositol signaling system_Homo sapiens_hsa040700.24828411
112Systemic lupus erythematosus_Homo sapiens_hsa053220.23766264
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.23757977
114Phagosome_Homo sapiens_hsa041450.22579451
115Type II diabetes mellitus_Homo sapiens_hsa049300.22233988
116Folate biosynthesis_Homo sapiens_hsa007900.22079320
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.22003870
118SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19188868
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.19047221
120Arachidonic acid metabolism_Homo sapiens_hsa005900.17882931
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.16893109
122alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.16690435
123mTOR signaling pathway_Homo sapiens_hsa041500.15931529
124ABC transporters_Homo sapiens_hsa020100.15545637
125Amoebiasis_Homo sapiens_hsa051460.14785745
126Choline metabolism in cancer_Homo sapiens_hsa052310.14262152
127Renal cell carcinoma_Homo sapiens_hsa052110.14239629
128Complement and coagulation cascades_Homo sapiens_hsa046100.08972290
129Prostate cancer_Homo sapiens_hsa052150.08732843
130Glycerolipid metabolism_Homo sapiens_hsa005610.05707142

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