

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein localization to chromosome, centromeric region (GO:0071459) | 7.53647836 |
| 2 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 7.01087908 |
| 3 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 7.01087908 |
| 4 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 7.01087908 |
| 5 | protein localization to kinetochore (GO:0034501) | 6.63448210 |
| 6 | positive regulation of chromosome segregation (GO:0051984) | 6.35329423 |
| 7 | mitotic metaphase plate congression (GO:0007080) | 6.07082384 |
| 8 | regulation of spindle organization (GO:0090224) | 5.66186349 |
| 9 | mitotic chromosome condensation (GO:0007076) | 5.46175720 |
| 10 | viral transcription (GO:0019083) | 5.39850657 |
| 11 | regulation of mitotic spindle organization (GO:0060236) | 5.35266035 |
| 12 | translational termination (GO:0006415) | 5.20022376 |
| 13 | attachment of spindle microtubules to kinetochore (GO:0008608) | 5.16206860 |
| 14 | metaphase plate congression (GO:0051310) | 5.11911226 |
| 15 | mitotic sister chromatid segregation (GO:0000070) | 4.96357426 |
| 16 | protein localization to chromosome (GO:0034502) | 4.91211517 |
| 17 | ribosomal small subunit biogenesis (GO:0042274) | 4.69554075 |
| 18 | establishment of chromosome localization (GO:0051303) | 4.55327159 |
| 19 | ribosomal small subunit assembly (GO:0000028) | 4.54154398 |
| 20 | translational elongation (GO:0006414) | 4.50267723 |
| 21 | sister chromatid segregation (GO:0000819) | 4.45889299 |
| 22 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.31747548 |
| 23 | regulation of sister chromatid cohesion (GO:0007063) | 4.30652315 |
| 24 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.29868435 |
| 25 | cotranslational protein targeting to membrane (GO:0006613) | 4.27333222 |
| 26 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 4.26517075 |
| 27 | protein targeting to ER (GO:0045047) | 4.22408781 |
| 28 | maturation of SSU-rRNA (GO:0030490) | 4.21465945 |
| 29 | cellular protein complex disassembly (GO:0043624) | 4.21450825 |
| 30 | regulation of chromosome segregation (GO:0051983) | 4.20706950 |
| 31 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.15843277 |
| 32 | kinetochore organization (GO:0051383) | 4.11416547 |
| 33 | translational initiation (GO:0006413) | 4.09051348 |
| 34 | ribosomal large subunit biogenesis (GO:0042273) | 4.08464317 |
| 35 | meiotic cell cycle (GO:0051321) | 4.07719123 |
| 36 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.06234771 |
| 37 | regulation of mitotic sister chromatid separation (GO:0010965) | 4.06052652 |
| 38 | regulation of mitotic sister chromatid segregation (GO:0033047) | 4.06052652 |
| 39 | regulation of sister chromatid segregation (GO:0033045) | 4.06052652 |
| 40 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 4.03859918 |
| 41 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 4.03859918 |
| 42 | DNA strand elongation (GO:0022616) | 3.99734433 |
| 43 | protein K6-linked ubiquitination (GO:0085020) | 3.96765357 |
| 44 | viral life cycle (GO:0019058) | 3.94829815 |
| 45 | protein localization to endoplasmic reticulum (GO:0070972) | 3.94144380 |
| 46 | CENP-A containing nucleosome assembly (GO:0034080) | 3.91925218 |
| 47 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.90090742 |
| 48 | negative regulation of chromosome segregation (GO:0051985) | 3.80890739 |
| 49 | spindle checkpoint (GO:0031577) | 3.79562952 |
| 50 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 3.74046349 |
| 51 | protein complex disassembly (GO:0043241) | 3.72509830 |
| 52 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.68890294 |
| 53 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.68890294 |
| 54 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.68890294 |
| 55 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.68890294 |
| 56 | negative regulation of sister chromatid segregation (GO:0033046) | 3.68890294 |
| 57 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.66327662 |
| 58 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.65568538 |
| 59 | chromatin remodeling at centromere (GO:0031055) | 3.58941847 |
| 60 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.57068383 |
| 61 | mitotic spindle checkpoint (GO:0071174) | 3.55694808 |
| 62 | DNA damage response, detection of DNA damage (GO:0042769) | 3.55086031 |
| 63 | DNA topological change (GO:0006265) | 3.54250308 |
| 64 | DNA ligation (GO:0006266) | 3.53204009 |
| 65 | macromolecular complex disassembly (GO:0032984) | 3.52327096 |
| 66 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.51320394 |
| 67 | mitotic spindle assembly checkpoint (GO:0007094) | 3.51091531 |
| 68 | purine nucleobase biosynthetic process (GO:0009113) | 3.46254505 |
| 69 | IMP biosynthetic process (GO:0006188) | 3.45327647 |
| 70 | kinetochore assembly (GO:0051382) | 3.43064471 |
| 71 | spindle assembly checkpoint (GO:0071173) | 3.41842656 |
| 72 | regulation of RNA export from nucleus (GO:0046831) | 3.39554115 |
| 73 | regulation of mitochondrial translation (GO:0070129) | 3.38700314 |
| 74 | histone exchange (GO:0043486) | 3.38574493 |
| 75 | DNA unwinding involved in DNA replication (GO:0006268) | 3.37768936 |
| 76 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.34158629 |
| 77 | mitotic nuclear envelope disassembly (GO:0007077) | 3.31916815 |
| 78 | telomere maintenance via recombination (GO:0000722) | 3.31272543 |
| 79 | mitochondrial fusion (GO:0008053) | 3.29290636 |
| 80 | chromosome condensation (GO:0030261) | 3.25318946 |
| 81 | establishment of integrated proviral latency (GO:0075713) | 3.25295362 |
| 82 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.17889482 |
| 83 | spliceosomal snRNP assembly (GO:0000387) | 3.15355765 |
| 84 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.14695739 |
| 85 | IMP metabolic process (GO:0046040) | 3.12240282 |
| 86 | DNA replication-independent nucleosome organization (GO:0034724) | 3.09909785 |
| 87 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.09909785 |
| 88 | mRNA catabolic process (GO:0006402) | 3.08487635 |
| 89 | inner mitochondrial membrane organization (GO:0007007) | 3.06180351 |
| 90 | ATP synthesis coupled proton transport (GO:0015986) | 3.03046892 |
| 91 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.03046892 |
| 92 | regulation of histone H3-K9 methylation (GO:0051570) | 3.02856997 |
| 93 | mitotic recombination (GO:0006312) | 3.02308180 |
| 94 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.01349324 |
| 95 | chromosome segregation (GO:0007059) | 3.00580431 |
| 96 | negative regulation of histone methylation (GO:0031061) | 2.99111038 |
| 97 | nuclear envelope disassembly (GO:0051081) | 2.98704920 |
| 98 | membrane disassembly (GO:0030397) | 2.98704920 |
| 99 | nucleobase biosynthetic process (GO:0046112) | 2.98340390 |
| 100 | RNA catabolic process (GO:0006401) | 2.96161836 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.25321889 |
| 2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 7.02199793 |
| 3 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 4.68878900 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.41236647 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.39862711 |
| 6 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 4.09051568 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.55332783 |
| 8 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.38351397 |
| 9 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.37196005 |
| 10 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.16301351 |
| 11 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.11964312 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.04614488 |
| 13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.80016676 |
| 14 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.75274709 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.74977499 |
| 16 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.72938450 |
| 17 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.59542062 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.57635678 |
| 19 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.46536778 |
| 20 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.46183814 |
| 21 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.35522554 |
| 22 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.28588676 |
| 23 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.28142226 |
| 24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.27449548 |
| 25 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.26729226 |
| 26 | MYC_22102868_ChIP-Seq_BL_Human | 2.09106799 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.06888070 |
| 28 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.05962485 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04295910 |
| 30 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.03918645 |
| 31 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.96351592 |
| 32 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.95719053 |
| 33 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.89828034 |
| 34 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.86979129 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.85643467 |
| 36 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.83074837 |
| 37 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.79935541 |
| 38 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.75872323 |
| 39 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.73594165 |
| 40 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.72167909 |
| 41 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.70389962 |
| 42 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.68134405 |
| 43 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.62580644 |
| 44 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.61532955 |
| 45 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.59297921 |
| 46 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.58560874 |
| 47 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.58195894 |
| 48 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.56088504 |
| 49 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.49399214 |
| 50 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.48881219 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.44051547 |
| 52 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.43523175 |
| 53 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.42731062 |
| 54 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.40639500 |
| 55 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.39254717 |
| 56 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.38445106 |
| 57 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.38017291 |
| 58 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.34179159 |
| 59 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.32503254 |
| 60 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.30083575 |
| 61 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.29953960 |
| 62 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.21799472 |
| 63 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.17681603 |
| 64 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.16554717 |
| 65 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.14420115 |
| 66 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.12781615 |
| 67 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.10132587 |
| 68 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.06915883 |
| 69 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.05809260 |
| 70 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.05808356 |
| 71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.04240047 |
| 72 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.99930749 |
| 73 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.99795429 |
| 74 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.89945872 |
| 75 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.88726924 |
| 76 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88640025 |
| 77 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.86689318 |
| 78 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.86459066 |
| 79 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.85266045 |
| 80 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84906546 |
| 81 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.83029671 |
| 82 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.82642802 |
| 83 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.81668231 |
| 84 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.81618157 |
| 85 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.81413946 |
| 86 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.81338201 |
| 87 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.78507318 |
| 88 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.75959737 |
| 89 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.75729564 |
| 90 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.74820879 |
| 91 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.73656268 |
| 92 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.73388725 |
| 93 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.73217902 |
| 94 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.70264499 |
| 95 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.69858285 |
| 96 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.65893868 |
| 97 | EWS_26573619_Chip-Seq_HEK293_Human | 0.63158859 |
| 98 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.62642018 |
| 99 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.62371298 |
| 100 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.61003626 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 5.18245558 |
| 2 | MP0003111_abnormal_nucleus_morphology | 4.92908656 |
| 3 | MP0010094_abnormal_chromosome_stability | 4.69655552 |
| 4 | MP0003077_abnormal_cell_cycle | 3.98877757 |
| 5 | MP0006292_abnormal_olfactory_placode | 3.81434501 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 3.81139274 |
| 7 | MP0003718_maternal_effect | 3.11941565 |
| 8 | MP0002138_abnormal_hepatobiliary_system | 3.03788711 |
| 9 | MP0009379_abnormal_foot_pigmentation | 2.88253310 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.81112838 |
| 11 | MP0008932_abnormal_embryonic_tissue | 2.36701746 |
| 12 | MP0001346_abnormal_lacrimal_gland | 2.34146663 |
| 13 | MP0008058_abnormal_DNA_repair | 2.22241533 |
| 14 | MP0008057_abnormal_DNA_replication | 2.18525669 |
| 15 | MP0002877_abnormal_melanocyte_morpholog | 2.14832375 |
| 16 | MP0002009_preneoplasia | 2.13101809 |
| 17 | MP0001293_anophthalmia | 1.99992267 |
| 18 | MP0003890_abnormal_embryonic-extraembry | 1.93012255 |
| 19 | MP0002163_abnormal_gland_morphology | 1.92607960 |
| 20 | MP0008007_abnormal_cellular_replicative | 1.83552557 |
| 21 | MP0001730_embryonic_growth_arrest | 1.82231412 |
| 22 | MP0000350_abnormal_cell_proliferation | 1.81583456 |
| 23 | MP0010030_abnormal_orbit_morphology | 1.78690382 |
| 24 | MP0001348_abnormal_lacrimal_gland | 1.78316706 |
| 25 | MP0006072_abnormal_retinal_apoptosis | 1.73195620 |
| 26 | MP0008789_abnormal_olfactory_epithelium | 1.67844411 |
| 27 | MP0006035_abnormal_mitochondrial_morpho | 1.66286179 |
| 28 | MP0002396_abnormal_hematopoietic_system | 1.65312224 |
| 29 | MP0002277_abnormal_respiratory_mucosa | 1.63127705 |
| 30 | MP0000685_abnormal_immune_system | 1.62025234 |
| 31 | MP0000490_abnormal_crypts_of | 1.61099779 |
| 32 | MP0002139_abnormal_hepatobiliary_system | 1.59850376 |
| 33 | MP0001529_abnormal_vocalization | 1.59427534 |
| 34 | MP0003786_premature_aging | 1.53501732 |
| 35 | MP0005380_embryogenesis_phenotype | 1.53252135 |
| 36 | MP0001672_abnormal_embryogenesis/_devel | 1.53252135 |
| 37 | MP0000313_abnormal_cell_death | 1.27976911 |
| 38 | MP0008961_abnormal_basal_metabolism | 1.27188570 |
| 39 | MP0002006_tumorigenesis | 1.26545124 |
| 40 | MP0003984_embryonic_growth_retardation | 1.26126385 |
| 41 | MP0003221_abnormal_cardiomyocyte_apopto | 1.25479317 |
| 42 | MP0001929_abnormal_gametogenesis | 1.23867899 |
| 43 | MP0000427_abnormal_hair_cycle | 1.22508959 |
| 44 | MP0003567_abnormal_fetal_cardiomyocyte | 1.22108661 |
| 45 | MP0001697_abnormal_embryo_size | 1.21444560 |
| 46 | MP0002088_abnormal_embryonic_growth/wei | 1.20991523 |
| 47 | MP0005394_taste/olfaction_phenotype | 1.20207512 |
| 48 | MP0005499_abnormal_olfactory_system | 1.20207512 |
| 49 | MP0002210_abnormal_sex_determination | 1.19992146 |
| 50 | MP0002166_altered_tumor_susceptibility | 1.18941403 |
| 51 | MP0005084_abnormal_gallbladder_morpholo | 1.06145370 |
| 52 | MP0002080_prenatal_lethality | 1.06124880 |
| 53 | MP0005379_endocrine/exocrine_gland_phen | 1.05879159 |
| 54 | MP0003938_abnormal_ear_development | 1.05034037 |
| 55 | MP0003763_abnormal_thymus_physiology | 1.03260380 |
| 56 | MP0003787_abnormal_imprinting | 0.95978753 |
| 57 | MP0002085_abnormal_embryonic_tissue | 0.94911415 |
| 58 | MP0002019_abnormal_tumor_incidence | 0.94605135 |
| 59 | MP0003699_abnormal_female_reproductive | 0.93890202 |
| 60 | MP0006036_abnormal_mitochondrial_physio | 0.87122634 |
| 61 | MP0001286_abnormal_eye_development | 0.86439661 |
| 62 | MP0003303_peritoneal_inflammation | 0.84392137 |
| 63 | MP0004510_myositis | 0.84217007 |
| 64 | MP0000733_abnormal_muscle_development | 0.83321648 |
| 65 | MP0003121_genomic_imprinting | 0.82713378 |
| 66 | MP0003315_abnormal_perineum_morphology | 0.82516958 |
| 67 | MP0000653_abnormal_sex_gland | 0.82343492 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.82150814 |
| 69 | MP0002092_abnormal_eye_morphology | 0.80493533 |
| 70 | MP0001145_abnormal_male_reproductive | 0.80398283 |
| 71 | MP0004197_abnormal_fetal_growth/weight/ | 0.79935074 |
| 72 | MP0003300_gastrointestinal_ulcer | 0.79652992 |
| 73 | MP0000703_abnormal_thymus_morphology | 0.77890908 |
| 74 | MP0002161_abnormal_fertility/fecundity | 0.76701225 |
| 75 | MP0010307_abnormal_tumor_latency | 0.75381711 |
| 76 | MP0000613_abnormal_salivary_gland | 0.73728633 |
| 77 | MP0002233_abnormal_nose_morphology | 0.72841717 |
| 78 | MP0005645_abnormal_hypothalamus_physiol | 0.72709117 |
| 79 | MP0010234_abnormal_vibrissa_follicle | 0.72040088 |
| 80 | MP0002398_abnormal_bone_marrow | 0.69674768 |
| 81 | MP0009672_abnormal_birth_weight | 0.69530471 |
| 82 | MP0000749_muscle_degeneration | 0.68967224 |
| 83 | MP0002084_abnormal_developmental_patter | 0.67336618 |
| 84 | MP0002089_abnormal_postnatal_growth/wei | 0.67281121 |
| 85 | MP0005395_other_phenotype | 0.67257768 |
| 86 | MP0000358_abnormal_cell_content/ | 0.64497031 |
| 87 | MP0003136_yellow_coat_color | 0.64051891 |
| 88 | MP0001119_abnormal_female_reproductive | 0.62089376 |
| 89 | MP0000566_synostosis | 0.61946125 |
| 90 | MP0002722_abnormal_immune_system | 0.60120107 |
| 91 | MP0002697_abnormal_eye_size | 0.57926668 |
| 92 | MP0002095_abnormal_skin_pigmentation | 0.56676839 |
| 93 | MP0008995_early_reproductive_senescence | 0.56523863 |
| 94 | MP0000689_abnormal_spleen_morphology | 0.56303498 |
| 95 | MP0001835_abnormal_antigen_presentation | 0.55456080 |
| 96 | MP0003698_abnormal_male_reproductive | 0.55251626 |
| 97 | MP0001800_abnormal_humoral_immune | 0.54888745 |
| 98 | MP0001919_abnormal_reproductive_system | 0.54390212 |
| 99 | MP0002106_abnormal_muscle_physiology | 0.54375937 |
| 100 | MP0000631_abnormal_neuroendocrine_gland | 0.53726736 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 5.34016751 |
| 2 | Colon cancer (HP:0003003) | 4.78004373 |
| 3 | Chromsome breakage (HP:0040012) | 4.16404366 |
| 4 | Abnormality of chromosome segregation (HP:0002916) | 3.92624724 |
| 5 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.81464345 |
| 6 | Septo-optic dysplasia (HP:0100842) | 3.65439468 |
| 7 | Hyperglycinemia (HP:0002154) | 3.62104368 |
| 8 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.56666289 |
| 9 | Abnormal number of erythroid precursors (HP:0012131) | 3.50022120 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.44693556 |
| 11 | Macrocytic anemia (HP:0001972) | 3.31252611 |
| 12 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.99704586 |
| 13 | Rectovaginal fistula (HP:0000143) | 2.99136175 |
| 14 | Rectal fistula (HP:0100590) | 2.99136175 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 2.97032243 |
| 16 | Absent septum pellucidum (HP:0001331) | 2.94116236 |
| 17 | Impulsivity (HP:0100710) | 2.82198525 |
| 18 | Embryonal renal neoplasm (HP:0011794) | 2.76747217 |
| 19 | Abnormality of glycolysis (HP:0004366) | 2.73866425 |
| 20 | Abnormal lung lobation (HP:0002101) | 2.70339000 |
| 21 | Increased serum pyruvate (HP:0003542) | 2.69970859 |
| 22 | Birth length less than 3rd percentile (HP:0003561) | 2.68680311 |
| 23 | Hyperglycinuria (HP:0003108) | 2.65801636 |
| 24 | Gout (HP:0001997) | 2.64521722 |
| 25 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.63969186 |
| 26 | Abnormality of glycine metabolism (HP:0010895) | 2.63969186 |
| 27 | Abnormality of chromosome stability (HP:0003220) | 2.62941437 |
| 28 | Progressive external ophthalmoplegia (HP:0000590) | 2.60128484 |
| 29 | Intestinal fistula (HP:0100819) | 2.59446583 |
| 30 | Neoplasm of the colon (HP:0100273) | 2.58446828 |
| 31 | Vaginal fistula (HP:0004320) | 2.51787644 |
| 32 | Embryonal neoplasm (HP:0002898) | 2.47633986 |
| 33 | Abnormality of the labia minora (HP:0012880) | 2.47443960 |
| 34 | Decreased circulating renin level (HP:0003351) | 2.47115277 |
| 35 | Transitional cell carcinoma of the bladder (HP:0006740) | 2.43594311 |
| 36 | Increased nuchal translucency (HP:0010880) | 2.41152706 |
| 37 | Limb hypertonia (HP:0002509) | 2.39921373 |
| 38 | Thickened helices (HP:0000391) | 2.39321134 |
| 39 | Premature ovarian failure (HP:0008209) | 2.37877276 |
| 40 | Abnormality of the septum pellucidum (HP:0007375) | 2.36043384 |
| 41 | Microvesicular hepatic steatosis (HP:0001414) | 2.34746060 |
| 42 | IgM deficiency (HP:0002850) | 2.33763214 |
| 43 | Myelodysplasia (HP:0002863) | 2.33709816 |
| 44 | Progressive muscle weakness (HP:0003323) | 2.33450882 |
| 45 | Pallor (HP:0000980) | 2.28011025 |
| 46 | Small intestinal stenosis (HP:0012848) | 2.26113887 |
| 47 | Duodenal stenosis (HP:0100867) | 2.26113887 |
| 48 | Partial duplication of thumb phalanx (HP:0009944) | 2.25337056 |
| 49 | Hepatic necrosis (HP:0002605) | 2.23954893 |
| 50 | Trigonocephaly (HP:0000243) | 2.22828526 |
| 51 | Rhabdomyosarcoma (HP:0002859) | 2.20761609 |
| 52 | Bladder carcinoma (HP:0002862) | 2.19964260 |
| 53 | Bladder neoplasm (HP:0009725) | 2.19964260 |
| 54 | Abnormality of the ileum (HP:0001549) | 2.16750732 |
| 55 | Chronic sinusitis (HP:0011109) | 2.16249040 |
| 56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.14142651 |
| 57 | Increased CSF lactate (HP:0002490) | 2.13748642 |
| 58 | Abnormality of the anterior horn cell (HP:0006802) | 2.10577953 |
| 59 | Degeneration of anterior horn cells (HP:0002398) | 2.10577953 |
| 60 | Hypokinesia (HP:0002375) | 2.09768045 |
| 61 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.07765298 |
| 62 | Uterine leiomyosarcoma (HP:0002891) | 2.07737251 |
| 63 | Leiomyosarcoma (HP:0100243) | 2.07737251 |
| 64 | Mitochondrial inheritance (HP:0001427) | 2.05825729 |
| 65 | Type I transferrin isoform profile (HP:0003642) | 2.05347128 |
| 66 | Meckel diverticulum (HP:0002245) | 2.05052261 |
| 67 | Supernumerary spleens (HP:0009799) | 2.02953633 |
| 68 | Pancytopenia (HP:0001876) | 2.02590463 |
| 69 | Impaired proprioception (HP:0010831) | 2.01882177 |
| 70 | Exertional dyspnea (HP:0002875) | 2.01006089 |
| 71 | Maternal diabetes (HP:0009800) | 1.98530567 |
| 72 | Abnormality of the duodenum (HP:0002246) | 1.96273226 |
| 73 | Acute encephalopathy (HP:0006846) | 1.93969310 |
| 74 | Increased serum lactate (HP:0002151) | 1.93136655 |
| 75 | Hepatocellular necrosis (HP:0001404) | 1.92648127 |
| 76 | Facial hemangioma (HP:0000329) | 1.92414992 |
| 77 | Broad palm (HP:0001169) | 1.91537818 |
| 78 | Horseshoe kidney (HP:0000085) | 1.91315654 |
| 79 | Triphalangeal thumb (HP:0001199) | 1.90693816 |
| 80 | Acute necrotizing encephalopathy (HP:0006965) | 1.90565499 |
| 81 | Duplication of thumb phalanx (HP:0009942) | 1.90067527 |
| 82 | Volvulus (HP:0002580) | 1.87508233 |
| 83 | Abnormality of the preputium (HP:0100587) | 1.86328922 |
| 84 | Generalized aminoaciduria (HP:0002909) | 1.85726764 |
| 85 | Enlarged penis (HP:0000040) | 1.84006793 |
| 86 | Progressive sensorineural hearing impairment (HP:0000408) | 1.83648424 |
| 87 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.83606762 |
| 88 | Oligodactyly (hands) (HP:0001180) | 1.83029037 |
| 89 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.81956946 |
| 90 | Gastrointestinal carcinoma (HP:0002672) | 1.81956946 |
| 91 | Progressive hearing impairment (HP:0001730) | 1.81798817 |
| 92 | 11 pairs of ribs (HP:0000878) | 1.80992579 |
| 93 | Abnormality of abdominal situs (HP:0011620) | 1.80483551 |
| 94 | Abdominal situs inversus (HP:0003363) | 1.80483551 |
| 95 | Partial duplication of the phalanx of hand (HP:0009999) | 1.79989784 |
| 96 | Increased intramyocellular lipid droplets (HP:0012240) | 1.79227099 |
| 97 | Abnormality of the pons (HP:0007361) | 1.78943215 |
| 98 | Abnormal ciliary motility (HP:0012262) | 1.78183198 |
| 99 | Abnormality of serum amino acid levels (HP:0003112) | 1.77705107 |
| 100 | Acute lymphatic leukemia (HP:0006721) | 1.76751445 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 6.04911631 |
| 2 | VRK2 | 4.05075935 |
| 3 | CDC7 | 3.60409886 |
| 4 | ARAF | 3.15927486 |
| 5 | TAF1 | 3.03049835 |
| 6 | TTK | 2.94506864 |
| 7 | SMG1 | 2.69144999 |
| 8 | PASK | 2.47190800 |
| 9 | MAP3K13 | 2.35899511 |
| 10 | SRPK1 | 2.14045484 |
| 11 | TSSK6 | 2.13034245 |
| 12 | STK24 | 2.12132170 |
| 13 | NEK1 | 2.05729761 |
| 14 | VRK1 | 1.84722387 |
| 15 | CDK9 | 1.82196011 |
| 16 | MAP3K14 | 1.75908928 |
| 17 | CDK4 | 1.73865405 |
| 18 | STK10 | 1.71075702 |
| 19 | STK16 | 1.67513843 |
| 20 | NME2 | 1.61646475 |
| 21 | WEE1 | 1.61304593 |
| 22 | TIE1 | 1.59394873 |
| 23 | CHEK2 | 1.58242484 |
| 24 | PLK3 | 1.57634077 |
| 25 | MAP3K8 | 1.51980675 |
| 26 | MELK | 1.51077911 |
| 27 | MST4 | 1.47329648 |
| 28 | PLK1 | 1.40797952 |
| 29 | CDK12 | 1.31155648 |
| 30 | MAP3K9 | 1.30607831 |
| 31 | AURKA | 1.30170263 |
| 32 | AURKB | 1.29796573 |
| 33 | ZAK | 1.29483512 |
| 34 | BRAF | 1.26692398 |
| 35 | STK4 | 1.24115584 |
| 36 | EIF2AK3 | 1.24018155 |
| 37 | CDK3 | 1.22170926 |
| 38 | RPS6KB2 | 1.17794317 |
| 39 | TNIK | 1.17787261 |
| 40 | NEK2 | 1.13073592 |
| 41 | CDK7 | 1.11292124 |
| 42 | CDK8 | 1.09432070 |
| 43 | MKNK2 | 1.06585979 |
| 44 | MAP3K10 | 1.01521343 |
| 45 | CCNB1 | 1.00067999 |
| 46 | MAP4K1 | 0.99845003 |
| 47 | MKNK1 | 0.91978147 |
| 48 | CHEK1 | 0.90332971 |
| 49 | ATR | 0.86104155 |
| 50 | BCR | 0.85075115 |
| 51 | CLK1 | 0.83692406 |
| 52 | EIF2AK2 | 0.83446113 |
| 53 | PLK4 | 0.80124628 |
| 54 | MOS | 0.78768139 |
| 55 | CDK6 | 0.78526176 |
| 56 | NME1 | 0.75965753 |
| 57 | PAK1 | 0.74640437 |
| 58 | EEF2K | 0.73114125 |
| 59 | PIM2 | 0.71156804 |
| 60 | CDK11A | 0.65886441 |
| 61 | ALK | 0.65872160 |
| 62 | CDK15 | 0.65418771 |
| 63 | NUAK1 | 0.65275606 |
| 64 | EIF2AK1 | 0.63054316 |
| 65 | PAK4 | 0.62838309 |
| 66 | RAF1 | 0.60178172 |
| 67 | CDK18 | 0.59440851 |
| 68 | CDK2 | 0.59235939 |
| 69 | PBK | 0.57083682 |
| 70 | MAPKAPK5 | 0.54924038 |
| 71 | TGFBR1 | 0.54781488 |
| 72 | CDK1 | 0.54721108 |
| 73 | CDK14 | 0.53975452 |
| 74 | ATM | 0.53864115 |
| 75 | PIM1 | 0.53673794 |
| 76 | MATK | 0.52542696 |
| 77 | NLK | 0.50961405 |
| 78 | STK3 | 0.50098089 |
| 79 | MAP2K2 | 0.48265463 |
| 80 | PKN2 | 0.46549609 |
| 81 | DMPK | 0.45644443 |
| 82 | LATS2 | 0.44356461 |
| 83 | CSNK2A2 | 0.39560692 |
| 84 | CHUK | 0.38535667 |
| 85 | SCYL2 | 0.37871689 |
| 86 | CSNK2A1 | 0.37340820 |
| 87 | TRIM28 | 0.36613459 |
| 88 | PDK2 | 0.36579468 |
| 89 | DYRK3 | 0.36356096 |
| 90 | DDR2 | 0.35523005 |
| 91 | NEK9 | 0.32978361 |
| 92 | AKT2 | 0.31465501 |
| 93 | BRSK1 | 0.30843649 |
| 94 | IKBKB | 0.29086604 |
| 95 | DAPK1 | 0.27595675 |
| 96 | BMPR1B | 0.27129745 |
| 97 | LRRK2 | 0.27026683 |
| 98 | MAP3K5 | 0.25887407 |
| 99 | CSNK1G3 | 0.24159809 |
| 100 | TNK2 | 0.23880757 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.03311530 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 4.29893268 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.71046876 |
| 4 | Cell cycle_Homo sapiens_hsa04110 | 3.36756720 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 3.34532097 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 3.03009441 |
| 7 | Spliceosome_Homo sapiens_hsa03040 | 2.73832916 |
| 8 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.66775269 |
| 9 | Base excision repair_Homo sapiens_hsa03410 | 2.64710994 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.58589876 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.47784606 |
| 12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.36918920 |
| 13 | RNA transport_Homo sapiens_hsa03013 | 2.16581908 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.16286374 |
| 15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.11706764 |
| 16 | p53 signaling pathway_Homo sapiens_hsa04115 | 2.05534668 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.95560940 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.92222704 |
| 19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.91901533 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.90808545 |
| 21 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.80053357 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.67064368 |
| 23 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.57804427 |
| 24 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.53916727 |
| 25 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.51026075 |
| 26 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.47930004 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.46230187 |
| 28 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.44846661 |
| 29 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.37552568 |
| 30 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.37431276 |
| 31 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.30849083 |
| 32 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.23408509 |
| 33 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.23229840 |
| 34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.22070488 |
| 35 | Alzheimers disease_Homo sapiens_hsa05010 | 1.10247597 |
| 36 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.09473173 |
| 37 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.00216692 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 0.99719269 |
| 39 | Carbon metabolism_Homo sapiens_hsa01200 | 0.93323875 |
| 40 | Sulfur relay system_Homo sapiens_hsa04122 | 0.91237662 |
| 41 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.90696274 |
| 42 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.90501285 |
| 43 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.82947212 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.81508903 |
| 45 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.80995509 |
| 46 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.80547480 |
| 47 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.78530769 |
| 48 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.78298187 |
| 49 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.78070953 |
| 50 | HTLV-I infection_Homo sapiens_hsa05166 | 0.78017273 |
| 51 | Apoptosis_Homo sapiens_hsa04210 | 0.76861331 |
| 52 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.70952790 |
| 53 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.66943969 |
| 54 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.62261239 |
| 55 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.60464586 |
| 56 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.59012054 |
| 57 | Thyroid cancer_Homo sapiens_hsa05216 | 0.54538798 |
| 58 | Protein export_Homo sapiens_hsa03060 | 0.52819068 |
| 59 | Influenza A_Homo sapiens_hsa05164 | 0.52444401 |
| 60 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.49918036 |
| 61 | Allograft rejection_Homo sapiens_hsa05330 | 0.49230058 |
| 62 | Hepatitis B_Homo sapiens_hsa05161 | 0.47980694 |
| 63 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.47379672 |
| 64 | Bladder cancer_Homo sapiens_hsa05219 | 0.44660756 |
| 65 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.44576438 |
| 66 | Colorectal cancer_Homo sapiens_hsa05210 | 0.42436375 |
| 67 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42257171 |
| 68 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.40011186 |
| 69 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.39597330 |
| 70 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.37464657 |
| 71 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.35901399 |
| 72 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.35746257 |
| 73 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.33067241 |
| 74 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.32793590 |
| 75 | Prostate cancer_Homo sapiens_hsa05215 | 0.31410070 |
| 76 | Viral myocarditis_Homo sapiens_hsa05416 | 0.29214031 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.27221265 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.25869898 |
| 79 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.25294258 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25145251 |
| 81 | Legionellosis_Homo sapiens_hsa05134 | 0.24856700 |
| 82 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.23961935 |
| 83 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.22121295 |
| 84 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.21941596 |
| 85 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.20369526 |
| 86 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.20062937 |
| 87 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.19675367 |
| 88 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.19099675 |
| 89 | Shigellosis_Homo sapiens_hsa05131 | 0.18937686 |
| 90 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.18367989 |
| 91 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.17084662 |
| 92 | Asthma_Homo sapiens_hsa05310 | 0.16007675 |
| 93 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.15964159 |
| 94 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.15604211 |
| 95 | Melanoma_Homo sapiens_hsa05218 | 0.14937838 |
| 96 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.14710895 |
| 97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.14392706 |
| 98 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.13804830 |
| 99 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.13413149 |
| 100 | Measles_Homo sapiens_hsa05162 | 0.13250877 |

