Rank | Gene Set | Z-score |
---|---|---|
1 | proteasome assembly (GO:0043248) | 5.50739417 |
2 | ribosomal small subunit assembly (GO:0000028) | 5.16807781 |
3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.86738002 |
4 | cytidine metabolic process (GO:0046087) | 4.65797689 |
5 | cytidine catabolic process (GO:0006216) | 4.65797689 |
6 | cytidine deamination (GO:0009972) | 4.65797689 |
7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.64888522 |
8 | ATP synthesis coupled proton transport (GO:0015986) | 4.64888522 |
9 | cullin deneddylation (GO:0010388) | 4.63288630 |
10 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.53141352 |
11 | protein deneddylation (GO:0000338) | 4.51757363 |
12 | formation of translation preinitiation complex (GO:0001731) | 4.51019062 |
13 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.38320792 |
14 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.32052823 |
15 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.32052823 |
16 | NADH dehydrogenase complex assembly (GO:0010257) | 4.32052823 |
17 | viral mRNA export from host cell nucleus (GO:0046784) | 4.31268500 |
18 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.23842600 |
19 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.18981299 |
20 | protein complex biogenesis (GO:0070271) | 4.14857505 |
21 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.11411362 |
22 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.11392985 |
23 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.10904706 |
24 | negative regulation of ligase activity (GO:0051352) | 4.10904706 |
25 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.07624533 |
26 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.03158112 |
27 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.03158112 |
28 | DNA deamination (GO:0045006) | 4.03013803 |
29 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.02858200 |
30 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.02858200 |
31 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.02858200 |
32 | ubiquinone biosynthetic process (GO:0006744) | 4.02607020 |
33 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.01982440 |
34 | maturation of SSU-rRNA (GO:0030490) | 4.00473128 |
35 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.99367504 |
36 | termination of RNA polymerase III transcription (GO:0006386) | 3.99367504 |
37 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.99304362 |
38 | protein neddylation (GO:0045116) | 3.98839712 |
39 | oxidative phosphorylation (GO:0006119) | 3.95107541 |
40 | chaperone-mediated protein transport (GO:0072321) | 3.92568013 |
41 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.89747665 |
42 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.89747665 |
43 | 7-methylguanosine mRNA capping (GO:0006370) | 3.86434634 |
44 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.86105943 |
45 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.85846041 |
46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.84841764 |
47 | purine nucleobase biosynthetic process (GO:0009113) | 3.84685399 |
48 | ribosomal small subunit biogenesis (GO:0042274) | 3.84176894 |
49 | ubiquinone metabolic process (GO:0006743) | 3.80987020 |
50 | RNA capping (GO:0036260) | 3.79005976 |
51 | 7-methylguanosine RNA capping (GO:0009452) | 3.79005976 |
52 | peptidyl-histidine modification (GO:0018202) | 3.77732465 |
53 | respiratory chain complex IV assembly (GO:0008535) | 3.74351605 |
54 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.74166149 |
55 | regulation of mitochondrial translation (GO:0070129) | 3.73532047 |
56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.73186799 |
57 | nucleobase biosynthetic process (GO:0046112) | 3.73174003 |
58 | actin-myosin filament sliding (GO:0033275) | 3.66616235 |
59 | muscle filament sliding (GO:0030049) | 3.66616235 |
60 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.66007675 |
61 | viral transcription (GO:0019083) | 3.65665328 |
62 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.65309016 |
63 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.59969435 |
64 | respiratory electron transport chain (GO:0022904) | 3.56971709 |
65 | translational termination (GO:0006415) | 3.55789803 |
66 | platelet dense granule organization (GO:0060155) | 3.55290924 |
67 | ribosomal large subunit biogenesis (GO:0042273) | 3.55128199 |
68 | electron transport chain (GO:0022900) | 3.52695155 |
69 | positive regulation of ligase activity (GO:0051351) | 3.49996139 |
70 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.48751339 |
71 | rRNA modification (GO:0000154) | 3.48455784 |
72 | translation (GO:0006412) | 3.48439472 |
73 | cytochrome complex assembly (GO:0017004) | 3.47296613 |
74 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.46413148 |
75 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.45221234 |
76 | cotranslational protein targeting to membrane (GO:0006613) | 3.42496316 |
77 | base-excision repair, AP site formation (GO:0006285) | 3.41894226 |
78 | cellular component biogenesis (GO:0044085) | 3.41180065 |
79 | positive regulation of prostaglandin secretion (GO:0032308) | 3.38250595 |
80 | metallo-sulfur cluster assembly (GO:0031163) | 3.37717793 |
81 | iron-sulfur cluster assembly (GO:0016226) | 3.37717793 |
82 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.37643851 |
83 | protein targeting to ER (GO:0045047) | 3.37132504 |
84 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.35970649 |
85 | behavioral response to nicotine (GO:0035095) | 3.35923699 |
86 | maturation of 5.8S rRNA (GO:0000460) | 3.35905109 |
87 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.35362458 |
88 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.35362458 |
89 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.34177022 |
90 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.33839883 |
91 | spliceosomal snRNP assembly (GO:0000387) | 3.33469918 |
92 | branched-chain amino acid catabolic process (GO:0009083) | 3.32335455 |
93 | telomere maintenance via recombination (GO:0000722) | 3.32292130 |
94 | translational elongation (GO:0006414) | 3.31291847 |
95 | ATP biosynthetic process (GO:0006754) | 3.30551423 |
96 | positive regulation of cell cycle arrest (GO:0071158) | 3.29791249 |
97 | DNA strand elongation (GO:0022616) | 3.28649710 |
98 | translational initiation (GO:0006413) | 3.25603393 |
99 | hydrogen ion transmembrane transport (GO:1902600) | 3.25101409 |
100 | protein localization to endoplasmic reticulum (GO:0070972) | 3.24373059 |
101 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.23592488 |
102 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.22931242 |
103 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.22796808 |
104 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.22328502 |
105 | protein targeting to mitochondrion (GO:0006626) | 3.22057399 |
106 | heart process (GO:0003015) | 3.18457120 |
107 | heart contraction (GO:0060047) | 3.18457120 |
108 | ribosome biogenesis (GO:0042254) | 3.17924808 |
109 | negative regulation of telomere maintenance (GO:0032205) | 3.16826849 |
110 | regulation of skeletal muscle contraction (GO:0014819) | 3.16739901 |
111 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.16347291 |
112 | DNA replication checkpoint (GO:0000076) | 3.14760115 |
113 | establishment of protein localization to mitochondrion (GO:0072655) | 3.14586565 |
114 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.14577651 |
115 | mitotic metaphase plate congression (GO:0007080) | 3.13311504 |
116 | regulation of ligase activity (GO:0051340) | 3.11368449 |
117 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.10861983 |
118 | deoxyribonucleotide catabolic process (GO:0009264) | 3.10777250 |
119 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.10572655 |
120 | cell cycle G1/S phase transition (GO:0044843) | 3.09576047 |
121 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.09576047 |
122 | CENP-A containing nucleosome assembly (GO:0034080) | 3.08486675 |
123 | quinone biosynthetic process (GO:1901663) | 3.07880679 |
124 | proton transport (GO:0015992) | 3.07543304 |
125 | transcription from RNA polymerase I promoter (GO:0006360) | 3.06181374 |
126 | rRNA processing (GO:0006364) | 3.05990017 |
127 | hydrogen transport (GO:0006818) | 3.02767596 |
128 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.01941847 |
129 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.00134788 |
130 | pseudouridine synthesis (GO:0001522) | 2.98875228 |
131 | mannosylation (GO:0097502) | 2.92967290 |
132 | deoxyribose phosphate catabolic process (GO:0046386) | 2.90867218 |
133 | actin-mediated cell contraction (GO:0070252) | 2.89944723 |
134 | amino acid salvage (GO:0043102) | 2.87842213 |
135 | L-methionine salvage (GO:0071267) | 2.87842213 |
136 | L-methionine biosynthetic process (GO:0071265) | 2.87842213 |
137 | aerobic respiration (GO:0009060) | 2.79876079 |
138 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.76514401 |
139 | intracellular protein transmembrane import (GO:0044743) | 2.74252629 |
140 | protein localization to mitochondrion (GO:0070585) | 2.72786686 |
141 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.68740957 |
142 | aldehyde catabolic process (GO:0046185) | 2.67670778 |
143 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.67130667 |
144 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.66919373 |
145 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.66547590 |
146 | branched-chain amino acid metabolic process (GO:0009081) | 2.62811461 |
Rank | Gene Set | Z-score |
---|---|---|
1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.81682161 |
2 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.26930737 |
3 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.24142981 |
4 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.21790570 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.18890905 |
6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.16119350 |
7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.76303559 |
8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.68726804 |
9 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.62378701 |
10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.49575514 |
11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.37337693 |
12 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.23613791 |
13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.14070438 |
14 | * CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.08214315 |
15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.04800407 |
16 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.89676421 |
17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.79167947 |
18 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.70567720 |
19 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.69828151 |
20 | * SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.69822175 |
21 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.64476643 |
22 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.62827615 |
23 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.57696717 |
24 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.47455348 |
25 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.47012132 |
26 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.45068123 |
27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.39044419 |
28 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.38180238 |
29 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.37969916 |
30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.36225438 |
31 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.32429319 |
32 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.31335616 |
33 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.23015777 |
34 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.22381072 |
35 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.20689019 |
36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.14407696 |
37 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.09142246 |
38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.00923910 |
39 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.93438881 |
40 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.92029631 |
41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.91567701 |
42 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.84471699 |
43 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.81297917 |
44 | VDR_22108803_ChIP-Seq_LS180_Human | 1.79547146 |
45 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.79424156 |
46 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.78870694 |
47 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.77552584 |
48 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.74921461 |
49 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.74150407 |
50 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.67215741 |
51 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.66307975 |
52 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.65225690 |
53 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.62697840 |
54 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62656669 |
55 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.54642863 |
56 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.53354618 |
57 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.51788310 |
58 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.48963166 |
59 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.46270237 |
60 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.46217585 |
61 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.44330390 |
62 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.42597308 |
63 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42562201 |
64 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.41823587 |
65 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.40668017 |
66 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.39037050 |
67 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.34955519 |
68 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.34918659 |
69 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.32007951 |
70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.31650499 |
71 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.29406472 |
72 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28464467 |
73 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.27519127 |
74 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.24416899 |
75 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.24184837 |
76 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.23018182 |
77 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.19577191 |
78 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19473997 |
79 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.17361211 |
80 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.13767974 |
81 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.12885859 |
82 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11857658 |
83 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.10239963 |
84 | AR_20517297_ChIP-Seq_VCAP_Human | 1.09927921 |
85 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.09389541 |
86 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.09304694 |
87 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.09028906 |
88 | EWS_26573619_Chip-Seq_HEK293_Human | 1.08554964 |
89 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.08358933 |
90 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.06738000 |
91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.05217570 |
92 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.05217570 |
93 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.04475549 |
94 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.03803655 |
95 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.03151972 |
96 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.03008845 |
97 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.02419542 |
98 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.02367482 |
99 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.01978481 |
100 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.01708118 |
101 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.00697127 |
102 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.00692448 |
103 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.00369193 |
104 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.99819397 |
105 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.99390213 |
106 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.97736960 |
107 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.97728753 |
108 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.97051924 |
109 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.96432855 |
110 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.96432855 |
111 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.95391535 |
112 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.93653291 |
113 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.93529661 |
114 | * SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.91779732 |
115 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.91628642 |
116 | * CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.91274414 |
117 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.91070787 |
118 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.90804312 |
119 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90157392 |
120 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.89645104 |
121 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.89554405 |
122 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.87967921 |
123 | FUS_26573619_Chip-Seq_HEK293_Human | 0.87962635 |
124 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.86088224 |
125 | NCOR_22424771_ChIP-Seq_293T_Human | 0.86010800 |
126 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.85564672 |
127 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.85407612 |
128 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.85342485 |
129 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.81311315 |
130 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.81092220 |
131 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.80412175 |
132 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.79264472 |
133 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.78188480 |
134 | * CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.78000425 |
135 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.76628873 |
136 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.75144982 |
137 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.74040790 |
138 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.73059820 |
139 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.72671122 |
140 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.71990866 |
141 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.70711804 |
142 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.69619004 |
143 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.69342927 |
144 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.67250012 |
145 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.66821210 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.81153137 |
2 | MP0004957_abnormal_blastocyst_morpholog | 3.42608597 |
3 | MP0003077_abnormal_cell_cycle | 3.00546183 |
4 | MP0010094_abnormal_chromosome_stability | 2.95381988 |
5 | MP0008058_abnormal_DNA_repair | 2.92532117 |
6 | MP0003111_abnormal_nucleus_morphology | 2.86007668 |
7 | MP0006292_abnormal_olfactory_placode | 2.83380165 |
8 | MP0008932_abnormal_embryonic_tissue | 2.48172824 |
9 | MP0003646_muscle_fatigue | 2.45244370 |
10 | MP0008057_abnormal_DNA_replication | 2.40820658 |
11 | MP0003011_delayed_dark_adaptation | 2.37436749 |
12 | MP0008007_abnormal_cellular_replicative | 2.36420929 |
13 | MP0008877_abnormal_DNA_methylation | 2.33090855 |
14 | MP0004084_abnormal_cardiac_muscle | 2.31796730 |
15 | MP0003123_paternal_imprinting | 2.29511078 |
16 | MP0003137_abnormal_impulse_conducting | 2.15926269 |
17 | MP0002254_reproductive_system_inflammat | 2.15621641 |
18 | MP0006036_abnormal_mitochondrial_physio | 2.10049838 |
19 | MP0006072_abnormal_retinal_apoptosis | 2.09585199 |
20 | MP0000749_muscle_degeneration | 2.06650103 |
21 | MP0003195_calcinosis | 2.05714763 |
22 | MP0003122_maternal_imprinting | 2.03619705 |
23 | MP0003786_premature_aging | 1.96781136 |
24 | MP0003806_abnormal_nucleotide_metabolis | 1.91340308 |
25 | MP0002837_dystrophic_cardiac_calcinosis | 1.86306009 |
26 | MP0002638_abnormal_pupillary_reflex | 1.83400393 |
27 | MP0003718_maternal_effect | 1.82610713 |
28 | MP0009379_abnormal_foot_pigmentation | 1.79570329 |
29 | MP0001529_abnormal_vocalization | 1.78136569 |
30 | MP0001986_abnormal_taste_sensitivity | 1.75978391 |
31 | MP0003186_abnormal_redox_activity | 1.73625647 |
32 | MP0009697_abnormal_copulation | 1.72260696 |
33 | MP0004036_abnormal_muscle_relaxation | 1.71887064 |
34 | MP0003121_genomic_imprinting | 1.70878451 |
35 | MP0005253_abnormal_eye_physiology | 1.56791937 |
36 | MP0004133_heterotaxia | 1.56231551 |
37 | MP0003567_abnormal_fetal_cardiomyocyte | 1.53474830 |
38 | MP0002653_abnormal_ependyma_morphology | 1.49711123 |
39 | MP0000372_irregular_coat_pigmentation | 1.48624005 |
40 | MP0002396_abnormal_hematopoietic_system | 1.46578176 |
41 | MP0001485_abnormal_pinna_reflex | 1.45996521 |
42 | MP0005551_abnormal_eye_electrophysiolog | 1.44966936 |
43 | MP0006035_abnormal_mitochondrial_morpho | 1.44544337 |
44 | MP0008875_abnormal_xenobiotic_pharmacok | 1.44315495 |
45 | MP0002938_white_spotting | 1.44238613 |
46 | MP0001984_abnormal_olfaction | 1.44234592 |
47 | MP0004142_abnormal_muscle_tone | 1.44192012 |
48 | MP0001905_abnormal_dopamine_level | 1.44179886 |
49 | MP0005671_abnormal_response_to | 1.43914960 |
50 | MP0000751_myopathy | 1.42887996 |
51 | MP0003787_abnormal_imprinting | 1.41003619 |
52 | MP0004215_abnormal_myocardial_fiber | 1.40660734 |
53 | MP0003315_abnormal_perineum_morphology | 1.39730739 |
54 | MP0005394_taste/olfaction_phenotype | 1.39215699 |
55 | MP0005499_abnormal_olfactory_system | 1.39215699 |
56 | MP0006054_spinal_hemorrhage | 1.37032490 |
57 | MP0008872_abnormal_physiological_respon | 1.36545370 |
58 | MP0005084_abnormal_gallbladder_morpholo | 1.34333685 |
59 | MP0002234_abnormal_pharynx_morphology | 1.33540034 |
60 | MP0002127_abnormal_cardiovascular_syste | 1.32913057 |
61 | MP0002163_abnormal_gland_morphology | 1.31396418 |
62 | MP0004145_abnormal_muscle_electrophysio | 1.30726571 |
63 | MP0004147_increased_porphyrin_level | 1.28989372 |
64 | MP0002132_abnormal_respiratory_system | 1.23397829 |
65 | MP0003221_abnormal_cardiomyocyte_apopto | 1.22629296 |
66 | MP0005330_cardiomyopathy | 1.21258891 |
67 | MP0010030_abnormal_orbit_morphology | 1.20270701 |
68 | MP0001730_embryonic_growth_arrest | 1.16335748 |
69 | MP0002106_abnormal_muscle_physiology | 1.13258266 |
70 | MP0008995_early_reproductive_senescence | 1.09809350 |
71 | MP0001968_abnormal_touch/_nociception | 1.06599697 |
72 | MP0005377_hearing/vestibular/ear_phenot | 1.05499077 |
73 | MP0003878_abnormal_ear_physiology | 1.05499077 |
74 | MP0000350_abnormal_cell_proliferation | 1.05261247 |
75 | MP0002102_abnormal_ear_morphology | 1.04283262 |
76 | MP0002160_abnormal_reproductive_system | 1.03940830 |
77 | MP0003941_abnormal_skin_development | 1.03415574 |
78 | MP0010386_abnormal_urinary_bladder | 1.03226885 |
79 | MP0005075_abnormal_melanosome_morpholog | 1.01148336 |
80 | MP0000313_abnormal_cell_death | 1.00498316 |
81 | MP0004085_abnormal_heartbeat | 1.00458064 |
82 | MP0002876_abnormal_thyroid_physiology | 1.00098573 |
83 | MP0005646_abnormal_pituitary_gland | 0.99718821 |
84 | MP0009840_abnormal_foam_cell | 0.98872553 |
85 | MP0002972_abnormal_cardiac_muscle | 0.98127487 |
86 | MP0006276_abnormal_autonomic_nervous | 0.95965988 |
87 | MP0001544_abnormal_cardiovascular_syste | 0.95098281 |
88 | MP0005385_cardiovascular_system_phenoty | 0.95098281 |
89 | MP0005645_abnormal_hypothalamus_physiol | 0.94966780 |
90 | MP0000678_abnormal_parathyroid_gland | 0.94470343 |
91 | MP0009764_decreased_sensitivity_to | 0.94388802 |
92 | MP0002751_abnormal_autonomic_nervous | 0.94173004 |
93 | MP0001697_abnormal_embryo_size | 0.93606357 |
94 | MP0005332_abnormal_amino_acid | 0.93017304 |
95 | MP0002148_abnormal_hypersensitivity_rea | 0.91609287 |
96 | MP0001293_anophthalmia | 0.91153386 |
97 | MP0002090_abnormal_vision | 0.91067762 |
98 | MP0000750_abnormal_muscle_regeneration | 0.90744221 |
99 | MP0000358_abnormal_cell_content/ | 0.89168874 |
100 | MP0003136_yellow_coat_color | 0.88792567 |
101 | MP0002736_abnormal_nociception_after | 0.88781281 |
102 | MP0005266_abnormal_metabolism | 0.88731128 |
103 | MP0009785_altered_susceptibility_to | 0.88675389 |
104 | MP0005389_reproductive_system_phenotype | 0.88099040 |
105 | MP0005410_abnormal_fertilization | 0.87390808 |
106 | MP0005171_absent_coat_pigmentation | 0.87316814 |
107 | MP0008260_abnormal_autophagy | 0.85601067 |
108 | MP0001873_stomach_inflammation | 0.85398613 |
109 | MP0001764_abnormal_homeostasis | 0.85290918 |
110 | MP0008789_abnormal_olfactory_epithelium | 0.84794440 |
111 | MP0005379_endocrine/exocrine_gland_phen | 0.84677577 |
112 | MP0005369_muscle_phenotype | 0.84471584 |
113 | MP0003880_abnormal_central_pattern | 0.84174299 |
114 | MP0002080_prenatal_lethality | 0.82714797 |
115 | MP0005397_hematopoietic_system_phenotyp | 0.82441513 |
116 | MP0001545_abnormal_hematopoietic_system | 0.82441513 |
117 | MP0004808_abnormal_hematopoietic_stem | 0.82133448 |
118 | MP0000566_synostosis | 0.81946005 |
119 | MP0009046_muscle_twitch | 0.80448355 |
120 | MP0000490_abnormal_crypts_of | 0.80417037 |
121 | MP0002822_catalepsy | 0.80385289 |
122 | MP0000049_abnormal_middle_ear | 0.79480716 |
123 | MP0006138_congestive_heart_failure | 0.79324376 |
124 | MP0002138_abnormal_hepatobiliary_system | 0.79062939 |
125 | MP0001672_abnormal_embryogenesis/_devel | 0.77650132 |
126 | MP0005380_embryogenesis_phenotype | 0.77650132 |
127 | MP0002210_abnormal_sex_determination | 0.77563580 |
128 | MP0004087_abnormal_muscle_fiber | 0.77250962 |
129 | MP0005408_hypopigmentation | 0.77204943 |
130 | MP0000343_altered_response_to | 0.74913777 |
131 | MP0000230_abnormal_systemic_arterial | 0.74641993 |
132 | MP0001542_abnormal_bone_strength | 0.74507160 |
133 | MP0001188_hyperpigmentation | 0.73694236 |
134 | MP0002272_abnormal_nervous_system | 0.72815962 |
135 | MP0004782_abnormal_surfactant_physiolog | 0.72652621 |
136 | MP0001727_abnormal_embryo_implantation | 0.72251404 |
137 | MP0002332_abnormal_exercise_endurance | 0.71901161 |
138 | MP0003984_embryonic_growth_retardation | 0.71701350 |
139 | MP0002735_abnormal_chemical_nociception | 0.71502888 |
140 | MP0008775_abnormal_heart_ventricle | 0.71388063 |
141 | MP0002269_muscular_atrophy | 0.70159298 |
142 | MP0002277_abnormal_respiratory_mucosa | 0.70147194 |
143 | MP0002095_abnormal_skin_pigmentation | 0.69842931 |
144 | MP0002088_abnormal_embryonic_growth/wei | 0.69324557 |
145 | MP0009745_abnormal_behavioral_response | 0.68949226 |
146 | MP0005620_abnormal_muscle_contractility | 0.68905375 |
147 | MP0004484_altered_response_of | 0.68165547 |
148 | MP0005636_abnormal_mineral_homeostasis | 0.66323104 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 5.55667695 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.07990554 |
3 | Hepatocellular necrosis (HP:0001404) | 5.07928628 |
4 | Mitochondrial inheritance (HP:0001427) | 5.02919477 |
5 | Increased CSF lactate (HP:0002490) | 4.65712316 |
6 | Hepatic necrosis (HP:0002605) | 4.63735375 |
7 | Progressive macrocephaly (HP:0004481) | 4.32706314 |
8 | Acute encephalopathy (HP:0006846) | 4.24196182 |
9 | Increased serum lactate (HP:0002151) | 3.52526874 |
10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.50026019 |
11 | Exercise intolerance (HP:0003546) | 3.48187328 |
12 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.41215591 |
13 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.41215591 |
14 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.37560563 |
15 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.31841018 |
16 | Birth length less than 3rd percentile (HP:0003561) | 3.29194498 |
17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.28238053 |
18 | Reticulocytopenia (HP:0001896) | 3.25344620 |
19 | Lipid accumulation in hepatocytes (HP:0006561) | 3.24912835 |
20 | Abnormality of glycolysis (HP:0004366) | 3.20131243 |
21 | Increased serum pyruvate (HP:0003542) | 3.20131243 |
22 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.19905538 |
23 | Lactic acidosis (HP:0003128) | 3.14838470 |
24 | Abnormal number of erythroid precursors (HP:0012131) | 3.12405774 |
25 | Respiratory failure (HP:0002878) | 3.08192147 |
26 | Aplastic anemia (HP:0001915) | 3.07717910 |
27 | Nemaline bodies (HP:0003798) | 3.05913549 |
28 | Muscle fiber inclusion bodies (HP:0100299) | 3.03379226 |
29 | Abnormality of midbrain morphology (HP:0002418) | 3.00174792 |
30 | Molar tooth sign on MRI (HP:0002419) | 3.00174792 |
31 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.94251355 |
32 | Exertional dyspnea (HP:0002875) | 2.93761818 |
33 | Hyperglycinemia (HP:0002154) | 2.86030185 |
34 | Cerebral hypomyelination (HP:0006808) | 2.85223881 |
35 | Type I transferrin isoform profile (HP:0003642) | 2.82987703 |
36 | Exercise-induced muscle cramps (HP:0003710) | 2.72134711 |
37 | Cerebral edema (HP:0002181) | 2.62583087 |
38 | Renal Fanconi syndrome (HP:0001994) | 2.61598378 |
39 | Methylmalonic aciduria (HP:0012120) | 2.60789036 |
40 | Lethargy (HP:0001254) | 2.58886756 |
41 | Oral leukoplakia (HP:0002745) | 2.58322437 |
42 | Methylmalonic acidemia (HP:0002912) | 2.56258389 |
43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.53413628 |
44 | Dicarboxylic aciduria (HP:0003215) | 2.52932346 |
45 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.52932346 |
46 | Patellar aplasia (HP:0006443) | 2.46970132 |
47 | Increased intramyocellular lipid droplets (HP:0012240) | 2.46417310 |
48 | CNS demyelination (HP:0007305) | 2.46113704 |
49 | Type 2 muscle fiber atrophy (HP:0003554) | 2.43489970 |
50 | Optic disc pallor (HP:0000543) | 2.43338474 |
51 | Respiratory difficulties (HP:0002880) | 2.40755810 |
52 | Hyperglycinuria (HP:0003108) | 2.36070714 |
53 | Palpitations (HP:0001962) | 2.36039434 |
54 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.32632132 |
55 | Leukodystrophy (HP:0002415) | 2.32446836 |
56 | Breast hypoplasia (HP:0003187) | 2.31307757 |
57 | Rough bone trabeculation (HP:0100670) | 2.30398510 |
58 | Emotional lability (HP:0000712) | 2.29435366 |
59 | Carpal bone hypoplasia (HP:0001498) | 2.28184358 |
60 | Microvesicular hepatic steatosis (HP:0001414) | 2.26125144 |
61 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.24257986 |
62 | Abnormality of glycine metabolism (HP:0010895) | 2.24257986 |
63 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.23724926 |
64 | Macrocytic anemia (HP:0001972) | 2.23712298 |
65 | Myotonia (HP:0002486) | 2.23512129 |
66 | Degeneration of anterior horn cells (HP:0002398) | 2.22488573 |
67 | Abnormality of the anterior horn cell (HP:0006802) | 2.22488573 |
68 | Nephronophthisis (HP:0000090) | 2.17254343 |
69 | Myoglobinuria (HP:0002913) | 2.16504607 |
70 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.16326684 |
71 | Abnormality of alanine metabolism (HP:0010916) | 2.16326684 |
72 | Hyperalaninemia (HP:0003348) | 2.16326684 |
73 | Abnormality of the labia minora (HP:0012880) | 2.15817641 |
74 | Abnormality of the preputium (HP:0100587) | 2.14472187 |
75 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.13793698 |
76 | Increased muscle lipid content (HP:0009058) | 2.13086207 |
77 | Muscle fiber atrophy (HP:0100295) | 2.12619354 |
78 | Congenital stationary night blindness (HP:0007642) | 2.12174205 |
79 | Renal cortical cysts (HP:0000803) | 2.03334234 |
80 | Pancreatic fibrosis (HP:0100732) | 2.02552418 |
81 | Generalized aminoaciduria (HP:0002909) | 2.01607844 |
82 | Abnormal hair whorl (HP:0010721) | 2.01432692 |
83 | Meckel diverticulum (HP:0002245) | 2.00676416 |
84 | Irregular epiphyses (HP:0010582) | 2.00497060 |
85 | Pallor (HP:0000980) | 1.99755973 |
86 | Glycosuria (HP:0003076) | 1.99688737 |
87 | Abnormality of urine glucose concentration (HP:0011016) | 1.99688737 |
88 | Abnormal lung lobation (HP:0002101) | 1.98191304 |
89 | Microretrognathia (HP:0000308) | 1.97152827 |
90 | Abnormality of the ileum (HP:0001549) | 1.94491249 |
91 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.93876605 |
92 | Chromsome breakage (HP:0040012) | 1.92973539 |
93 | Abnormality of serum amino acid levels (HP:0003112) | 1.92569242 |
94 | Hypothermia (HP:0002045) | 1.92510682 |
95 | Rhabdomyolysis (HP:0003201) | 1.92504915 |
96 | Unsteady gait (HP:0002317) | 1.91322335 |
97 | True hermaphroditism (HP:0010459) | 1.90154992 |
98 | X-linked dominant inheritance (HP:0001423) | 1.90134960 |
99 | Patent foramen ovale (HP:0001655) | 1.88982052 |
100 | Neoplasm of the adrenal gland (HP:0100631) | 1.87552030 |
101 | Pancreatic cysts (HP:0001737) | 1.86316898 |
102 | Rimmed vacuoles (HP:0003805) | 1.84321658 |
103 | Increased IgM level (HP:0003496) | 1.83872371 |
104 | Double outlet right ventricle (HP:0001719) | 1.83185528 |
105 | Congenital malformation of the right heart (HP:0011723) | 1.83185528 |
106 | Nausea (HP:0002018) | 1.83078692 |
107 | Premature graying of hair (HP:0002216) | 1.82274874 |
108 | Abnormal trabecular bone morphology (HP:0100671) | 1.82169104 |
109 | Medial flaring of the eyebrow (HP:0010747) | 1.81872416 |
110 | Pancytopenia (HP:0001876) | 1.81192391 |
111 | Colon cancer (HP:0003003) | 1.80390311 |
112 | Attenuation of retinal blood vessels (HP:0007843) | 1.80239161 |
113 | Abnormal biliary tract physiology (HP:0012439) | 1.79428325 |
114 | Bile duct proliferation (HP:0001408) | 1.79428325 |
115 | Nephrogenic diabetes insipidus (HP:0009806) | 1.78973305 |
116 | Calf muscle hypertrophy (HP:0008981) | 1.77534800 |
117 | Neuroendocrine neoplasm (HP:0100634) | 1.77237156 |
118 | Gait imbalance (HP:0002141) | 1.77061973 |
119 | Left ventricular hypertrophy (HP:0001712) | 1.76948959 |
120 | Ketosis (HP:0001946) | 1.76731560 |
121 | Abnormality of the renal cortex (HP:0011035) | 1.76721984 |
122 | Decreased central vision (HP:0007663) | 1.74682789 |
123 | Abnormal protein glycosylation (HP:0012346) | 1.73169657 |
124 | Abnormal glycosylation (HP:0012345) | 1.73169657 |
125 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.73169657 |
126 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.73169657 |
127 | Absent thumb (HP:0009777) | 1.72836440 |
128 | Adrenal hypoplasia (HP:0000835) | 1.72805497 |
129 | Congenital primary aphakia (HP:0007707) | 1.70532039 |
130 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.70071572 |
131 | Multiple enchondromatosis (HP:0005701) | 1.69980328 |
132 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.69737177 |
133 | Bone marrow hypocellularity (HP:0005528) | 1.69581116 |
134 | Blindness (HP:0000618) | 1.69281979 |
135 | Exercise-induced myalgia (HP:0003738) | 1.68145201 |
136 | Esophageal neoplasm (HP:0100751) | 1.67592060 |
137 | Neoplasm of head and neck (HP:0012288) | 1.67592060 |
138 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.67405850 |
139 | Cerebral palsy (HP:0100021) | 1.67192763 |
140 | Delayed CNS myelination (HP:0002188) | 1.66595625 |
141 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.66364522 |
142 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.64567495 |
143 | Absent epiphyses (HP:0010577) | 1.64567495 |
144 | Metabolic acidosis (HP:0001942) | 1.64530219 |
145 | Sclerocornea (HP:0000647) | 1.62798630 |
146 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.61976829 |
147 | Anencephaly (HP:0002323) | 1.59130122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.28247713 |
2 | STK16 | 3.60944949 |
3 | WEE1 | 3.05085692 |
4 | NME2 | 2.87756666 |
5 | VRK2 | 2.86879856 |
6 | EIF2AK1 | 2.75335494 |
7 | TSSK6 | 2.69119927 |
8 | SRPK1 | 2.68864724 |
9 | OBSCN | 2.28453449 |
10 | MAP4K2 | 2.27729245 |
11 | MYLK | 2.26030284 |
12 | NUAK1 | 2.24667418 |
13 | PIM2 | 2.23082149 |
14 | PLK4 | 2.15496281 |
15 | EIF2AK3 | 2.13409118 |
16 | VRK1 | 2.05241597 |
17 | TXK | 1.99174967 |
18 | ZAK | 1.98734226 |
19 | ARAF | 1.97844769 |
20 | CCNB1 | 1.96549124 |
21 | WNK3 | 1.91859304 |
22 | GRK1 | 1.80793755 |
23 | PDK2 | 1.77118590 |
24 | NME1 | 1.76127322 |
25 | BRSK2 | 1.75813453 |
26 | MAP3K12 | 1.73969377 |
27 | BRAF | 1.73534946 |
28 | NEK1 | 1.68961883 |
29 | CDK8 | 1.56247976 |
30 | MKNK1 | 1.55363243 |
31 | FRK | 1.53309531 |
32 | AKT3 | 1.50903239 |
33 | MUSK | 1.50588276 |
34 | PHKG1 | 1.47763642 |
35 | PHKG2 | 1.47763642 |
36 | PLK3 | 1.47519791 |
37 | CSNK1G3 | 1.44470788 |
38 | SIK3 | 1.44115859 |
39 | MAPKAPK3 | 1.43830816 |
40 | TRIM28 | 1.39671658 |
41 | ADRBK2 | 1.38919318 |
42 | CDC7 | 1.36012447 |
43 | ACVR1B | 1.32513687 |
44 | PLK1 | 1.31695744 |
45 | CSNK1G1 | 1.27069553 |
46 | PIK3CA | 1.26992580 |
47 | CSNK1G2 | 1.25511949 |
48 | TGFBR1 | 1.20884363 |
49 | MKNK2 | 1.15634741 |
50 | BRSK1 | 1.09641133 |
51 | CASK | 1.08471072 |
52 | STK24 | 1.08209037 |
53 | CSNK1A1L | 1.07488712 |
54 | OXSR1 | 1.06367066 |
55 | INSRR | 1.04365308 |
56 | MST4 | 1.04171985 |
57 | PASK | 1.04034548 |
58 | DYRK2 | 1.02012297 |
59 | LIMK1 | 0.98963854 |
60 | TTK | 0.97378807 |
61 | STK38L | 0.95045674 |
62 | TAOK2 | 0.94391504 |
63 | AURKB | 0.92683567 |
64 | BCKDK | 0.92096175 |
65 | AURKA | 0.90123403 |
66 | DAPK3 | 0.88526468 |
67 | RPS6KB2 | 0.88310245 |
68 | EIF2AK2 | 0.87831348 |
69 | CDK7 | 0.86559905 |
70 | PINK1 | 0.84131235 |
71 | KIT | 0.82078830 |
72 | TESK1 | 0.81473020 |
73 | IRAK3 | 0.81214255 |
74 | ERBB3 | 0.80119709 |
75 | WNK4 | 0.79149772 |
76 | PLK2 | 0.78906566 |
77 | ATR | 0.76830174 |
78 | IRAK4 | 0.76188220 |
79 | EPHA2 | 0.75921682 |
80 | BCR | 0.75323396 |
81 | BMPR2 | 0.75204342 |
82 | CSNK2A1 | 0.74693662 |
83 | CHEK2 | 0.74226852 |
84 | DYRK3 | 0.74029067 |
85 | TIE1 | 0.72212558 |
86 | YES1 | 0.71509524 |
87 | PBK | 0.70873598 |
88 | PAK3 | 0.70052903 |
89 | NEK2 | 0.68657149 |
90 | PRKCG | 0.68279486 |
91 | BMPR1B | 0.67109238 |
92 | MAP3K6 | 0.66525683 |
93 | PDK4 | 0.64047262 |
94 | PDK3 | 0.64047262 |
95 | ILK | 0.63185062 |
96 | IKBKB | 0.63110989 |
97 | MAPK13 | 0.62123166 |
98 | GRK5 | 0.61549442 |
99 | PRKCE | 0.60302992 |
100 | PIK3CG | 0.60077628 |
101 | GRK7 | 0.58978135 |
102 | MAP3K5 | 0.58003415 |
103 | CSNK2A2 | 0.56889440 |
104 | TBK1 | 0.55897627 |
105 | PRKCI | 0.55833076 |
106 | TESK2 | 0.53906326 |
107 | TEC | 0.53476853 |
108 | MAP3K11 | 0.53445755 |
109 | MAP2K6 | 0.52891744 |
110 | RAF1 | 0.52451312 |
111 | MAP2K3 | 0.51382659 |
112 | PAK1 | 0.51109240 |
113 | KDR | 0.51025137 |
114 | PRKCQ | 0.50471270 |
115 | TNIK | 0.49431311 |
116 | CAMK2A | 0.49390766 |
117 | DAPK1 | 0.48527421 |
118 | TLK1 | 0.47017867 |
119 | RPS6KL1 | 0.46427259 |
120 | RPS6KC1 | 0.46427259 |
121 | MAP3K4 | 0.46234416 |
122 | RPS6KA5 | 0.46062078 |
123 | PAK4 | 0.44797926 |
124 | PRKACA | 0.44690724 |
125 | RPS6KA6 | 0.44640650 |
126 | DAPK2 | 0.44547125 |
127 | ROCK1 | 0.44157674 |
128 | CAMK2D | 0.43929701 |
129 | CDK19 | 0.42507031 |
130 | CAMKK2 | 0.42205657 |
131 | ADRBK1 | 0.41342808 |
132 | ITK | 0.41244306 |
133 | STK4 | 0.40554253 |
134 | MAP2K7 | 0.40382027 |
135 | TAF1 | 0.39576502 |
136 | PKN1 | 0.39530093 |
137 | MAP3K3 | 0.39146305 |
138 | FLT3 | 0.39018763 |
139 | MAPK15 | 0.38256213 |
140 | PIM1 | 0.38036648 |
141 | ABL2 | 0.34465983 |
142 | CSNK1A1 | 0.34265685 |
143 | PRKCA | 0.34187654 |
144 | TAOK3 | 0.33020996 |
145 | SYK | 0.32248138 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 4.88972868 |
2 | Ribosome_Homo sapiens_hsa03010 | 4.12514220 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 3.80321479 |
4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.66990804 |
5 | DNA replication_Homo sapiens_hsa03030 | 3.46863655 |
6 | Parkinsons disease_Homo sapiens_hsa05012 | 3.35621080 |
7 | Mismatch repair_Homo sapiens_hsa03430 | 2.94002650 |
8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.70959784 |
9 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.61470601 |
10 | Spliceosome_Homo sapiens_hsa03040 | 2.57288395 |
11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.55272456 |
12 | Protein export_Homo sapiens_hsa03060 | 2.52031183 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 2.48500845 |
14 | Base excision repair_Homo sapiens_hsa03410 | 2.46271092 |
15 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.34743085 |
16 | RNA transport_Homo sapiens_hsa03013 | 2.22689807 |
17 | Alzheimers disease_Homo sapiens_hsa05010 | 2.16129308 |
18 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.12418187 |
19 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.08141336 |
20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.92569031 |
21 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.74776348 |
22 | RNA degradation_Homo sapiens_hsa03018 | 1.71429885 |
23 | Purine metabolism_Homo sapiens_hsa00230 | 1.65981160 |
24 | Cell cycle_Homo sapiens_hsa04110 | 1.63478486 |
25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.57072864 |
26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.52911678 |
27 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.50730049 |
28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.50230780 |
29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.32306157 |
30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.31440022 |
31 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.28998363 |
32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.28333388 |
33 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.20849737 |
34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.18336450 |
35 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.14116358 |
36 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.04239279 |
37 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.98575622 |
38 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.98168381 |
39 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.97764589 |
40 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.93530105 |
41 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.91278288 |
42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.90838345 |
43 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.89027430 |
44 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.87558639 |
45 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.83952862 |
46 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.82901302 |
47 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.82136422 |
48 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.81804609 |
49 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.78479910 |
50 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.76898822 |
51 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.75111203 |
52 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.74886902 |
53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.73621328 |
54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.72748075 |
55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.72582142 |
56 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.72497229 |
57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.70061502 |
58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.69525405 |
59 | Carbon metabolism_Homo sapiens_hsa01200 | 0.68722826 |
60 | Galactose metabolism_Homo sapiens_hsa00052 | 0.66598862 |
61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.66352951 |
62 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66313834 |
63 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.66290972 |
64 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.65760907 |
65 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64935239 |
66 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.63756175 |
67 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63601309 |
68 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.63239632 |
69 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.60774384 |
70 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.60639227 |
71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59739780 |
72 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.58773384 |
73 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.57981422 |
74 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.57947503 |
75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.57092528 |
76 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.57056207 |
77 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55404493 |
78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.50617334 |
79 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.48901311 |
80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.48607665 |
81 | Legionellosis_Homo sapiens_hsa05134 | 0.48294002 |
82 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.47396217 |
83 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.47334572 |
84 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.46840504 |
85 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.42876411 |
86 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.42839210 |
87 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.42001580 |
88 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.41733819 |
89 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.40191848 |
90 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38797593 |
91 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.36528762 |
92 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.34475745 |
93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34371868 |
94 | Retinol metabolism_Homo sapiens_hsa00830 | 0.34123017 |
95 | Phagosome_Homo sapiens_hsa04145 | 0.33563229 |
96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.32719404 |
97 | Allograft rejection_Homo sapiens_hsa05330 | 0.32712876 |
98 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.27934648 |
99 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.27123779 |
100 | Sulfur relay system_Homo sapiens_hsa04122 | 0.26712509 |
101 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26532736 |
102 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.25759827 |
103 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25236707 |
104 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.25029310 |
105 | Asthma_Homo sapiens_hsa05310 | 0.23714509 |
106 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.22105623 |
107 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.20334229 |
108 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.17693355 |
109 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.16425767 |
110 | Thyroid cancer_Homo sapiens_hsa05216 | 0.16323745 |
111 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.14761278 |
112 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.13293587 |
113 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.13202833 |
114 | Phototransduction_Homo sapiens_hsa04744 | 0.11390650 |
115 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.11097087 |
116 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.10613424 |
117 | Shigellosis_Homo sapiens_hsa05131 | 0.10106646 |
118 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.09786195 |
119 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.08736296 |
120 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.08320256 |
121 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.07057626 |
122 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.06972620 |
123 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.06592638 |
124 | Other glycan degradation_Homo sapiens_hsa00511 | 0.06408917 |
125 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.06061035 |
126 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.05504961 |
127 | HTLV-I infection_Homo sapiens_hsa05166 | 0.05338024 |
128 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.04305428 |
129 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.02284575 |
130 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.00793994 |
131 | Peroxisome_Homo sapiens_hsa04146 | 0.00710066 |