

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | detection of molecule of bacterial origin (GO:0032490) | 6.39158189 |
| 2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.27226697 |
| 3 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.91503306 |
| 4 | microglial cell activation (GO:0001774) | 5.63584728 |
| 5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.62327869 |
| 6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.62327869 |
| 7 | modulation by symbiont of host immune response (GO:0052553) | 5.62327869 |
| 8 | positive regulation by symbiont of host defense response (GO:0052509) | 5.62327869 |
| 9 | modulation by symbiont of host defense response (GO:0052031) | 5.62327869 |
| 10 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.62327869 |
| 11 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.41612727 |
| 12 | negative regulation of cell killing (GO:0031342) | 5.26436242 |
| 13 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.26436242 |
| 14 | macrophage activation involved in immune response (GO:0002281) | 4.84571287 |
| 15 | neutrophil mediated immunity (GO:0002446) | 4.72720022 |
| 16 | macrophage activation (GO:0042116) | 4.69029366 |
| 17 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.60653940 |
| 18 | cellular extravasation (GO:0045123) | 4.59277287 |
| 19 | negative regulation of interleukin-12 production (GO:0032695) | 4.56453442 |
| 20 | regulation of gamma-delta T cell activation (GO:0046643) | 4.56136460 |
| 21 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.54896848 |
| 22 | myeloid leukocyte mediated immunity (GO:0002444) | 4.44137363 |
| 23 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.43627415 |
| 24 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.43124515 |
| 25 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.38068799 |
| 26 | detection of external biotic stimulus (GO:0098581) | 4.35590857 |
| 27 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 4.34734076 |
| 28 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.30255264 |
| 29 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 4.20072991 |
| 30 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.04869540 |
| 31 | response to host immune response (GO:0052572) | 4.04869540 |
| 32 | hepatocyte apoptotic process (GO:0097284) | 3.93543331 |
| 33 | detection of biotic stimulus (GO:0009595) | 3.79634251 |
| 34 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.77490990 |
| 35 | response to host defenses (GO:0052200) | 3.74498673 |
| 36 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.74498673 |
| 37 | response to host (GO:0075136) | 3.74498673 |
| 38 | negative T cell selection (GO:0043383) | 3.72758245 |
| 39 | detection of other organism (GO:0098543) | 3.69939814 |
| 40 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.69132672 |
| 41 | positive thymic T cell selection (GO:0045059) | 3.68102424 |
| 42 | neutrophil activation involved in immune response (GO:0002283) | 3.65731938 |
| 43 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.63993252 |
| 44 | positive T cell selection (GO:0043368) | 3.61970970 |
| 45 | negative thymic T cell selection (GO:0045060) | 3.61765263 |
| 46 | respiratory burst (GO:0045730) | 3.60676786 |
| 47 | regulation of necroptotic process (GO:0060544) | 3.55277217 |
| 48 | negative regulation of T cell mediated immunity (GO:0002710) | 3.54912884 |
| 49 | response to peptidoglycan (GO:0032494) | 3.50978153 |
| 50 | dosage compensation (GO:0007549) | 3.46724668 |
| 51 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.42562418 |
| 52 | myeloid cell activation involved in immune response (GO:0002275) | 3.41573697 |
| 53 | positive regulation of interferon-alpha production (GO:0032727) | 3.39451652 |
| 54 | leukocyte aggregation (GO:0070486) | 3.38716755 |
| 55 | B cell receptor signaling pathway (GO:0050853) | 3.37478869 |
| 56 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.36789178 |
| 57 | negative regulation of B cell mediated immunity (GO:0002713) | 3.36789178 |
| 58 | negative regulation of B cell proliferation (GO:0030889) | 3.35008986 |
| 59 | defense response to protozoan (GO:0042832) | 3.32848924 |
| 60 | regulation of interferon-alpha production (GO:0032647) | 3.31372880 |
| 61 | regulation of beta-amyloid formation (GO:1902003) | 3.31256347 |
| 62 | histone H3-K36 demethylation (GO:0070544) | 3.24386292 |
| 63 | T-helper 1 type immune response (GO:0042088) | 3.18299609 |
| 64 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.13530433 |
| 65 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.10940874 |
| 66 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.08612381 |
| 67 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.08364669 |
| 68 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.08274858 |
| 69 | interferon-gamma production (GO:0032609) | 3.05505682 |
| 70 | type I interferon signaling pathway (GO:0060337) | 3.04281207 |
| 71 | cellular response to type I interferon (GO:0071357) | 3.04281207 |
| 72 | response to type I interferon (GO:0034340) | 3.03483371 |
| 73 | neutrophil activation (GO:0042119) | 3.03363891 |
| 74 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.02774009 |
| 75 | positive regulation of interferon-beta production (GO:0032728) | 2.98138227 |
| 76 | negative regulation of adaptive immune response (GO:0002820) | 2.95170892 |
| 77 | histone mRNA catabolic process (GO:0071044) | 2.93896329 |
| 78 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.93370692 |
| 79 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.92710438 |
| 80 | response to protozoan (GO:0001562) | 2.92467720 |
| 81 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.89649709 |
| 82 | negative regulation of interleukin-17 production (GO:0032700) | 2.89443254 |
| 83 | positive regulation of receptor recycling (GO:0001921) | 2.89101768 |
| 84 | negative regulation of complement activation (GO:0045916) | 2.87053461 |
| 85 | response to manganese ion (GO:0010042) | 2.84828128 |
| 86 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.84394343 |
| 87 | response to interleukin-15 (GO:0070672) | 2.83683703 |
| 88 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.83612067 |
| 89 | myeloid leukocyte activation (GO:0002274) | 2.82844227 |
| 90 | T cell migration (GO:0072678) | 2.82532519 |
| 91 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.82353276 |
| 92 | positive regulation of interleukin-1 production (GO:0032732) | 2.80879406 |
| 93 | I-kappaB phosphorylation (GO:0007252) | 2.80671180 |
| 94 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.78872545 |
| 95 | regulation of B cell differentiation (GO:0045577) | 2.78741720 |
| 96 | immunoglobulin mediated immune response (GO:0016064) | 2.78727300 |
| 97 | granulocyte activation (GO:0036230) | 2.78370180 |
| 98 | cellular response to ethanol (GO:0071361) | 2.77325333 |
| 99 | regulation of amyloid precursor protein catabolic process (GO:1902991) | 2.76039839 |
| 100 | detection of bacterium (GO:0016045) | 2.75021078 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.45463293 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.06897699 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.41507746 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.30872927 |
| 5 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.72015981 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.43618295 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.37197377 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.35957849 |
| 9 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.23577588 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.19821448 |
| 11 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.07944255 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.00807374 |
| 13 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.99495403 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.77101429 |
| 15 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.74760389 |
| 16 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.69938786 |
| 17 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.60133731 |
| 18 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.57608800 |
| 19 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.46598642 |
| 20 | MYB_26560356_Chip-Seq_TH2_Human | 2.36063795 |
| 21 | GATA1_22025678_ChIP-Seq_K562_Human | 2.26137021 |
| 22 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.17384877 |
| 23 | SPI1_23127762_ChIP-Seq_K562_Human | 2.16303125 |
| 24 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.11190413 |
| 25 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.91587383 |
| 26 | MYB_26560356_Chip-Seq_TH1_Human | 1.88867939 |
| 27 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.82926286 |
| 28 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.82143875 |
| 29 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.81140160 |
| 30 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.74683999 |
| 31 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.70076994 |
| 32 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.65221939 |
| 33 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.62805339 |
| 34 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.62536773 |
| 35 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.62448599 |
| 36 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.60943253 |
| 37 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.50533421 |
| 38 | GATA3_26560356_Chip-Seq_TH2_Human | 1.50335202 |
| 39 | GATA1_19941826_ChIP-Seq_K562_Human | 1.45787491 |
| 40 | MAF_26560356_Chip-Seq_TH1_Human | 1.44635127 |
| 41 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43193686 |
| 42 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.42212712 |
| 43 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.41999473 |
| 44 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.41472308 |
| 45 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.36202763 |
| 46 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.35234412 |
| 47 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.35225369 |
| 48 | GATA2_19941826_ChIP-Seq_K562_Human | 1.35004124 |
| 49 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.31370535 |
| 50 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.28901389 |
| 51 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.24322734 |
| 52 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.23478564 |
| 53 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22135733 |
| 54 | TP53_16413492_ChIP-PET_HCT116_Human | 1.19775393 |
| 55 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.19195637 |
| 56 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.17339187 |
| 57 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.11093758 |
| 58 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.09100552 |
| 59 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.09044968 |
| 60 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.08617829 |
| 61 | UTX_26944678_Chip-Seq_JUKART_Human | 1.07748243 |
| 62 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07012325 |
| 63 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04588427 |
| 64 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.01824558 |
| 65 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.97400744 |
| 66 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.94890406 |
| 67 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.94567527 |
| 68 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.93628279 |
| 69 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93248161 |
| 70 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.92785631 |
| 71 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.92771055 |
| 72 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.91975931 |
| 73 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.91169362 |
| 74 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.90688336 |
| 75 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.89764208 |
| 76 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.89574207 |
| 77 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.88419515 |
| 78 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.83894742 |
| 79 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.83261521 |
| 80 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.83240195 |
| 81 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.79904339 |
| 82 | MAF_26560356_Chip-Seq_TH2_Human | 0.79319346 |
| 83 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.79168918 |
| 84 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.78597931 |
| 85 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.77998901 |
| 86 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.77627285 |
| 87 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.76157738 |
| 88 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.74834044 |
| 89 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.74675488 |
| 90 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.73842040 |
| 91 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.73758319 |
| 92 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.72822344 |
| 93 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.72191350 |
| 94 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.71798063 |
| 95 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.71684214 |
| 96 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.71211195 |
| 97 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.70866838 |
| 98 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.70641437 |
| 99 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.70188561 |
| 100 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.69846581 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 5.36720171 |
| 2 | MP0008260_abnormal_autophagy | 4.60937506 |
| 3 | MP0003724_increased_susceptibility_to | 4.56569734 |
| 4 | MP0003303_peritoneal_inflammation | 3.48119062 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.41980198 |
| 6 | MP0005451_abnormal_body_composition | 3.05748678 |
| 7 | MP0003787_abnormal_imprinting | 2.81702108 |
| 8 | MP0003656_abnormal_erythrocyte_physiolo | 2.74694471 |
| 9 | MP0003436_decreased_susceptibility_to | 2.71725780 |
| 10 | MP0003172_abnormal_lysosome_physiology | 2.55650161 |
| 11 | MP0002419_abnormal_innate_immunity | 2.46517798 |
| 12 | MP0009785_altered_susceptibility_to | 2.44446515 |
| 13 | MP0001800_abnormal_humoral_immune | 2.41919875 |
| 14 | MP0000685_abnormal_immune_system | 2.25507005 |
| 15 | MP0004883_abnormal_blood_vessel | 2.23673112 |
| 16 | MP0004381_abnormal_hair_follicle | 2.20470349 |
| 17 | MP0005025_abnormal_response_to | 2.18686334 |
| 18 | MP0005000_abnormal_immune_tolerance | 2.09487519 |
| 19 | MP0002723_abnormal_immune_serum | 2.07746963 |
| 20 | MP0003300_gastrointestinal_ulcer | 2.06781604 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.04091454 |
| 22 | MP0005671_abnormal_response_to | 2.00402748 |
| 23 | MP0002166_altered_tumor_susceptibility | 1.96750244 |
| 24 | MP0002420_abnormal_adaptive_immunity | 1.94258212 |
| 25 | MP0001819_abnormal_immune_cell | 1.92363924 |
| 26 | MP0003763_abnormal_thymus_physiology | 1.88172568 |
| 27 | MP0006082_CNS_inflammation | 1.85048141 |
| 28 | MP0000015_abnormal_ear_pigmentation | 1.84016913 |
| 29 | MP0001790_abnormal_immune_system | 1.80945568 |
| 30 | MP0005387_immune_system_phenotype | 1.80945568 |
| 31 | MP0005464_abnormal_platelet_physiology | 1.74255268 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.73982690 |
| 33 | MP0003221_abnormal_cardiomyocyte_apopto | 1.72954857 |
| 34 | MP0002332_abnormal_exercise_endurance | 1.68266621 |
| 35 | MP0005164_abnormal_response_to | 1.66900671 |
| 36 | MP0002405_respiratory_system_inflammati | 1.65982528 |
| 37 | MP0003828_pulmonary_edema | 1.65158727 |
| 38 | MP0005174_abnormal_tail_pigmentation | 1.61102861 |
| 39 | MP0005310_abnormal_salivary_gland | 1.58783614 |
| 40 | MP0008877_abnormal_DNA_methylation | 1.58026687 |
| 41 | MP0002398_abnormal_bone_marrow | 1.57648808 |
| 42 | MP0009764_decreased_sensitivity_to | 1.57087130 |
| 43 | MP0000716_abnormal_immune_system | 1.55343766 |
| 44 | MP0001533_abnormal_skeleton_physiology | 1.51906805 |
| 45 | MP0004947_skin_inflammation | 1.51836856 |
| 46 | MP0001845_abnormal_inflammatory_respons | 1.45565220 |
| 47 | MP0003191_abnormal_cellular_cholesterol | 1.45546349 |
| 48 | MP0000604_amyloidosis | 1.45065637 |
| 49 | MP0002006_tumorigenesis | 1.40811940 |
| 50 | MP0005075_abnormal_melanosome_morpholog | 1.39435435 |
| 51 | MP0000858_altered_metastatic_potential | 1.35350059 |
| 52 | MP0000689_abnormal_spleen_morphology | 1.34626158 |
| 53 | MP0002722_abnormal_immune_system | 1.33377240 |
| 54 | MP0009278_abnormal_bone_marrow | 1.33327556 |
| 55 | MP0005397_hematopoietic_system_phenotyp | 1.31898073 |
| 56 | MP0001545_abnormal_hematopoietic_system | 1.31898073 |
| 57 | MP0003690_abnormal_glial_cell | 1.30620874 |
| 58 | MP0002429_abnormal_blood_cell | 1.20926626 |
| 59 | MP0008057_abnormal_DNA_replication | 1.17693342 |
| 60 | MP0003329_amyloid_beta_deposits | 1.16915114 |
| 61 | MP0004484_altered_response_of | 1.15214236 |
| 62 | MP0000703_abnormal_thymus_morphology | 1.12269823 |
| 63 | MP0002132_abnormal_respiratory_system | 1.11587943 |
| 64 | MP0004808_abnormal_hematopoietic_stem | 1.10992091 |
| 65 | MP0002396_abnormal_hematopoietic_system | 1.10069388 |
| 66 | MP0003075_altered_response_to | 1.09283414 |
| 67 | MP0006054_spinal_hemorrhage | 1.08918215 |
| 68 | MP0010155_abnormal_intestine_physiology | 1.07974473 |
| 69 | MP0001958_emphysema | 1.07065033 |
| 70 | MP0008469_abnormal_protein_level | 1.07058478 |
| 71 | MP0003866_abnormal_defecation | 1.06549074 |
| 72 | MP0000465_gastrointestinal_hemorrhage | 1.01618584 |
| 73 | MP0002998_abnormal_bone_remodeling | 1.01004235 |
| 74 | MP0003195_calcinosis | 1.00921552 |
| 75 | MP0001853_heart_inflammation | 0.99790083 |
| 76 | MP0003091_abnormal_cell_migration | 0.99721139 |
| 77 | MP0003121_genomic_imprinting | 0.99405494 |
| 78 | MP0001851_eye_inflammation | 0.90184931 |
| 79 | MP0005058_abnormal_lysosome_morphology | 0.88228632 |
| 80 | MP0009765_abnormal_xenobiotic_induced | 0.87965205 |
| 81 | MP0000371_diluted_coat_color | 0.86533449 |
| 82 | MP0003448_altered_tumor_morphology | 0.86481380 |
| 83 | MP0003183_abnormal_peptide_metabolism | 0.86396153 |
| 84 | MP0004510_myositis | 0.85093064 |
| 85 | MP0005376_homeostasis/metabolism_phenot | 0.82887789 |
| 86 | MP0009763_increased_sensitivity_to | 0.81341871 |
| 87 | MP0002277_abnormal_respiratory_mucosa | 0.78440052 |
| 88 | MP0005166_decreased_susceptibility_to | 0.76775148 |
| 89 | MP0005408_hypopigmentation | 0.75328091 |
| 90 | MP0008874_decreased_physiological_sensi | 0.74541072 |
| 91 | MP0000343_altered_response_to | 0.73790903 |
| 92 | MP0003632_abnormal_nervous_system | 0.73577761 |
| 93 | MP0000249_abnormal_blood_vessel | 0.72262944 |
| 94 | MP0002909_abnormal_adrenal_gland | 0.71537046 |
| 95 | MP0008004_abnormal_stomach_pH | 0.71404370 |
| 96 | MP0003646_muscle_fatigue | 0.71128937 |
| 97 | MP0004130_abnormal_muscle_cell | 0.69200747 |
| 98 | MP0005266_abnormal_metabolism | 0.65969365 |
| 99 | MP0005076_abnormal_cell_differentiation | 0.59850595 |
| 100 | MP0001663_abnormal_digestive_system | 0.59527590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 7.25107266 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 6.70183322 |
| 3 | Recurrent abscess formation (HP:0002722) | 5.86537546 |
| 4 | Eczematoid dermatitis (HP:0000976) | 5.69816410 |
| 5 | Retrobulbar optic neuritis (HP:0100654) | 5.57807098 |
| 6 | Optic neuritis (HP:0100653) | 5.57807098 |
| 7 | Orchitis (HP:0100796) | 5.33353908 |
| 8 | T lymphocytopenia (HP:0005403) | 5.26434778 |
| 9 | Myositis (HP:0100614) | 5.08098354 |
| 10 | Abnormality of T cell number (HP:0011839) | 4.92525096 |
| 11 | Gastrointestinal infarctions (HP:0005244) | 4.81362161 |
| 12 | Recurrent fungal infections (HP:0002841) | 4.37070356 |
| 13 | Peritonitis (HP:0002586) | 4.32258480 |
| 14 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.24518843 |
| 15 | Recurrent skin infections (HP:0001581) | 4.13878657 |
| 16 | Keratoconjunctivitis sicca (HP:0001097) | 4.12615387 |
| 17 | Gingivitis (HP:0000230) | 4.05954708 |
| 18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.84258033 |
| 19 | Keratoconjunctivitis (HP:0001096) | 3.80457897 |
| 20 | Gingival bleeding (HP:0000225) | 3.79633344 |
| 21 | Abnormality of macrophages (HP:0004311) | 3.71938035 |
| 22 | Stomatitis (HP:0010280) | 3.67995736 |
| 23 | Arterial thrombosis (HP:0004420) | 3.61477608 |
| 24 | Slow saccadic eye movements (HP:0000514) | 3.46932493 |
| 25 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.46342309 |
| 26 | Recurrent cutaneous fungal infections (HP:0011370) | 3.46342309 |
| 27 | Postural instability (HP:0002172) | 3.41389414 |
| 28 | Mediastinal lymphadenopathy (HP:0100721) | 3.33511534 |
| 29 | Spontaneous hematomas (HP:0007420) | 3.31565283 |
| 30 | Subacute progressive viral hepatitis (HP:0006572) | 3.22332870 |
| 31 | Resting tremor (HP:0002322) | 3.17870267 |
| 32 | Leukocytosis (HP:0001974) | 3.14808305 |
| 33 | Recurrent viral infections (HP:0004429) | 3.10479079 |
| 34 | Hemoptysis (HP:0002105) | 3.09286797 |
| 35 | Encephalitis (HP:0002383) | 3.05260177 |
| 36 | Abnormality of T cells (HP:0002843) | 2.98446454 |
| 37 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.97276505 |
| 38 | Vasculitis (HP:0002633) | 2.96075268 |
| 39 | Meningitis (HP:0001287) | 2.94688517 |
| 40 | Chest pain (HP:0100749) | 2.94586665 |
| 41 | Obstructive lung disease (HP:0006536) | 2.91167553 |
| 42 | Chronic obstructive pulmonary disease (HP:0006510) | 2.91167553 |
| 43 | Urticaria (HP:0001025) | 2.77862114 |
| 44 | Abnormality of the peritoneum (HP:0002585) | 2.70277621 |
| 45 | Periodontitis (HP:0000704) | 2.69188616 |
| 46 | Gangrene (HP:0100758) | 2.64973636 |
| 47 | Epistaxis (HP:0000421) | 2.63585557 |
| 48 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.58963024 |
| 49 | Eosinophilia (HP:0001880) | 2.57981715 |
| 50 | Pulmonary infiltrates (HP:0002113) | 2.56813334 |
| 51 | Anorexia (HP:0002039) | 2.55398408 |
| 52 | Viral hepatitis (HP:0006562) | 2.53926703 |
| 53 | Pelvic girdle muscle weakness (HP:0003749) | 2.53514940 |
| 54 | Pulmonary embolism (HP:0002204) | 2.50469629 |
| 55 | Visual hallucinations (HP:0002367) | 2.46379624 |
| 56 | Conjunctival telangiectasia (HP:0000524) | 2.45862153 |
| 57 | Acute hepatic failure (HP:0006554) | 2.42616535 |
| 58 | Cellulitis (HP:0100658) | 2.36845242 |
| 59 | Granulocytopenia (HP:0001913) | 2.31560349 |
| 60 | Recurrent bronchitis (HP:0002837) | 2.31499838 |
| 61 | Abnormality of the endocardium (HP:0004306) | 2.29241914 |
| 62 | Episodic fever (HP:0001954) | 2.22894758 |
| 63 | Abnormality of eosinophils (HP:0001879) | 2.20439559 |
| 64 | Prolonged bleeding time (HP:0003010) | 2.19507391 |
| 65 | Myocardial infarction (HP:0001658) | 2.14109911 |
| 66 | Amyloidosis (HP:0011034) | 2.13436517 |
| 67 | Autoimmune hemolytic anemia (HP:0001890) | 2.11456233 |
| 68 | Autoimmune thrombocytopenia (HP:0001973) | 2.11321652 |
| 69 | Inflammation of the large intestine (HP:0002037) | 2.11127791 |
| 70 | Papillary thyroid carcinoma (HP:0002895) | 2.08507712 |
| 71 | Fatigue (HP:0012378) | 2.05987453 |
| 72 | Keratitis (HP:0000491) | 2.04459577 |
| 73 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.04283346 |
| 74 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.04283346 |
| 75 | Cerebral inclusion bodies (HP:0100314) | 2.02509069 |
| 76 | Thyroiditis (HP:0100646) | 1.99682947 |
| 77 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.99679668 |
| 78 | Vertigo (HP:0002321) | 1.99387153 |
| 79 | Poikilocytosis (HP:0004447) | 1.96958338 |
| 80 | Glomerulopathy (HP:0100820) | 1.94589022 |
| 81 | Neurodegeneration (HP:0002180) | 1.92019915 |
| 82 | Orthostatic hypotension (HP:0001278) | 1.91556557 |
| 83 | Osteomyelitis (HP:0002754) | 1.91292746 |
| 84 | Colitis (HP:0002583) | 1.90843398 |
| 85 | Abnormality of the pleura (HP:0002103) | 1.90290475 |
| 86 | Gastrointestinal inflammation (HP:0004386) | 1.89637197 |
| 87 | Thrombophlebitis (HP:0004418) | 1.88257959 |
| 88 | IgA deficiency (HP:0002720) | 1.87648346 |
| 89 | Foot dorsiflexor weakness (HP:0009027) | 1.84770634 |
| 90 | Hematochezia (HP:0002573) | 1.83046977 |
| 91 | Hypoplasia of the thymus (HP:0000778) | 1.82135064 |
| 92 | Pustule (HP:0200039) | 1.81381146 |
| 93 | Amaurosis fugax (HP:0100576) | 1.77826358 |
| 94 | Microcytic anemia (HP:0001935) | 1.77700225 |
| 95 | Sepsis (HP:0100806) | 1.74674223 |
| 96 | Difficulty running (HP:0009046) | 1.73176303 |
| 97 | Stomach cancer (HP:0012126) | 1.72059113 |
| 98 | Acne (HP:0001061) | 1.68519401 |
| 99 | Cheilitis (HP:0100825) | 1.68158495 |
| 100 | Polyneuropathy (HP:0001271) | 1.68041892 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.37130134 |
| 2 | BLK | 3.52128997 |
| 3 | IRAK4 | 2.95414964 |
| 4 | IKBKE | 2.89748599 |
| 5 | MAP2K3 | 2.76593315 |
| 6 | FGR | 2.75370962 |
| 7 | CSK | 2.69487778 |
| 8 | GRK6 | 2.52733683 |
| 9 | JAK3 | 2.26865158 |
| 10 | TYK2 | 2.18165153 |
| 11 | MAP3K14 | 2.10607803 |
| 12 | MAP4K1 | 2.06531539 |
| 13 | TXK | 1.96584595 |
| 14 | BMPR2 | 1.92332801 |
| 15 | IRAK1 | 1.89774369 |
| 16 | TAOK3 | 1.86257715 |
| 17 | FES | 1.82294941 |
| 18 | FRK | 1.79179385 |
| 19 | PIK3CG | 1.74974398 |
| 20 | SYK | 1.72168521 |
| 21 | WNK1 | 1.71186481 |
| 22 | FGFR3 | 1.67295836 |
| 23 | IRAK2 | 1.66227067 |
| 24 | MAP3K2 | 1.63758560 |
| 25 | SGK2 | 1.56316383 |
| 26 | ZAP70 | 1.55703882 |
| 27 | STK4 | 1.54676491 |
| 28 | MATK | 1.54265495 |
| 29 | PTK2B | 1.51135772 |
| 30 | JAK1 | 1.47561333 |
| 31 | TAOK1 | 1.47282687 |
| 32 | MAP3K3 | 1.43493374 |
| 33 | BTK | 1.40711085 |
| 34 | LRRK2 | 1.32659710 |
| 35 | GRK5 | 1.30261277 |
| 36 | HCK | 1.29983349 |
| 37 | MAP3K1 | 1.29763040 |
| 38 | MAP3K11 | 1.26734540 |
| 39 | JAK2 | 1.25990637 |
| 40 | LYN | 1.24644019 |
| 41 | EPHB1 | 1.21246971 |
| 42 | PIM1 | 1.20015304 |
| 43 | SGK3 | 1.19674269 |
| 44 | ERBB2 | 1.14887402 |
| 45 | MARK3 | 1.11756961 |
| 46 | MAP3K6 | 1.11442685 |
| 47 | MAP3K13 | 1.09823191 |
| 48 | PLK2 | 1.09089176 |
| 49 | TBK1 | 1.03924703 |
| 50 | YES1 | 1.01819689 |
| 51 | TEC | 0.97978013 |
| 52 | KSR2 | 0.96962665 |
| 53 | KSR1 | 0.94596858 |
| 54 | MARK2 | 0.94586235 |
| 55 | MAP3K5 | 0.92762484 |
| 56 | TGFBR2 | 0.92479353 |
| 57 | LCK | 0.92386509 |
| 58 | ITK | 0.92156064 |
| 59 | RAF1 | 0.91961223 |
| 60 | TAOK2 | 0.91119494 |
| 61 | IKBKB | 0.90619528 |
| 62 | FGFR4 | 0.88532180 |
| 63 | CAMKK2 | 0.88096047 |
| 64 | SGK223 | 0.86190892 |
| 65 | SGK494 | 0.86190892 |
| 66 | NLK | 0.83896353 |
| 67 | ACVR1B | 0.83728094 |
| 68 | DYRK1A | 0.72294519 |
| 69 | KIT | 0.71689946 |
| 70 | TRPM7 | 0.71294201 |
| 71 | CSF1R | 0.70703173 |
| 72 | CHUK | 0.65193728 |
| 73 | STK11 | 0.64940313 |
| 74 | EGFR | 0.61226094 |
| 75 | PAK3 | 0.60624241 |
| 76 | CLK1 | 0.60155422 |
| 77 | SGK1 | 0.55667264 |
| 78 | EPHA3 | 0.54182388 |
| 79 | CDC42BPA | 0.50937910 |
| 80 | DYRK3 | 0.49895032 |
| 81 | PDK1 | 0.49221654 |
| 82 | MAP2K4 | 0.49216040 |
| 83 | STK10 | 0.48445674 |
| 84 | GRK7 | 0.45467119 |
| 85 | CAMK1D | 0.44947319 |
| 86 | MAP3K7 | 0.44480767 |
| 87 | PTK6 | 0.42703890 |
| 88 | FYN | 0.42578649 |
| 89 | CAMK4 | 0.42489354 |
| 90 | STK38 | 0.40446336 |
| 91 | MAP2K6 | 0.38235531 |
| 92 | TNK2 | 0.38182169 |
| 93 | NEK9 | 0.36224310 |
| 94 | PRKAA2 | 0.33879738 |
| 95 | PDGFRB | 0.33046960 |
| 96 | MELK | 0.32941369 |
| 97 | ADRBK1 | 0.30764685 |
| 98 | RET | 0.30082363 |
| 99 | DAPK2 | 0.27879789 |
| 100 | RIPK1 | 0.27721939 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.21061211 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.74444446 |
| 3 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.58636307 |
| 4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.43774896 |
| 5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.41940239 |
| 6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.25152605 |
| 7 | Tuberculosis_Homo sapiens_hsa05152 | 2.23224267 |
| 8 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.18002692 |
| 9 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.12337178 |
| 10 | Legionellosis_Homo sapiens_hsa05134 | 2.07167998 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.05062224 |
| 12 | Measles_Homo sapiens_hsa05162 | 1.96895930 |
| 13 | Malaria_Homo sapiens_hsa05144 | 1.96497403 |
| 14 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.95988951 |
| 15 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.84303875 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.79711445 |
| 17 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.77338665 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.71630635 |
| 19 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.67245089 |
| 20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.65761682 |
| 21 | Influenza A_Homo sapiens_hsa05164 | 1.63523795 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.59242682 |
| 23 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.57983773 |
| 24 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.54947730 |
| 25 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.53960738 |
| 26 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.52579772 |
| 27 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.40070750 |
| 28 | Hepatitis B_Homo sapiens_hsa05161 | 1.38869959 |
| 29 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.38301754 |
| 30 | Allograft rejection_Homo sapiens_hsa05330 | 1.35100100 |
| 31 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.34675833 |
| 32 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.34531651 |
| 33 | Hepatitis C_Homo sapiens_hsa05160 | 1.28730611 |
| 34 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.27060855 |
| 35 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.15725340 |
| 36 | Platelet activation_Homo sapiens_hsa04611 | 1.15109002 |
| 37 | Apoptosis_Homo sapiens_hsa04210 | 1.13932402 |
| 38 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.13563606 |
| 39 | Phagosome_Homo sapiens_hsa04145 | 1.13096933 |
| 40 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.13015525 |
| 41 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.12565199 |
| 42 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.10459689 |
| 43 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.10238749 |
| 44 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.09305346 |
| 45 | Pertussis_Homo sapiens_hsa05133 | 1.08450570 |
| 46 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.05345571 |
| 47 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.97369766 |
| 48 | Salmonella infection_Homo sapiens_hsa05132 | 0.96236612 |
| 49 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.95572181 |
| 50 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.93484122 |
| 51 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.92159027 |
| 52 | Endometrial cancer_Homo sapiens_hsa05213 | 0.92149909 |
| 53 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.92143844 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.91441680 |
| 55 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.90454195 |
| 56 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.88921739 |
| 57 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.85934716 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85685636 |
| 59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.84769375 |
| 60 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.84185789 |
| 61 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.82898421 |
| 62 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.82504771 |
| 63 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.79928929 |
| 64 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.79387100 |
| 65 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.78945538 |
| 66 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.78893047 |
| 67 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.70201944 |
| 68 | Shigellosis_Homo sapiens_hsa05131 | 0.69710057 |
| 69 | Amoebiasis_Homo sapiens_hsa05146 | 0.66902364 |
| 70 | Asthma_Homo sapiens_hsa05310 | 0.64165705 |
| 71 | Glioma_Homo sapiens_hsa05214 | 0.64137687 |
| 72 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.63740228 |
| 73 | Viral myocarditis_Homo sapiens_hsa05416 | 0.62964770 |
| 74 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.62140799 |
| 75 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.60303994 |
| 76 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.59644076 |
| 77 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.58585012 |
| 78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.58562506 |
| 79 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.58510607 |
| 80 | Insulin resistance_Homo sapiens_hsa04931 | 0.58341559 |
| 81 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.58175594 |
| 82 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.57444257 |
| 83 | Prostate cancer_Homo sapiens_hsa05215 | 0.52170381 |
| 84 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.51939026 |
| 85 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.51719117 |
| 86 | Lysosome_Homo sapiens_hsa04142 | 0.51594107 |
| 87 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.49959829 |
| 88 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.49404197 |
| 89 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.49325909 |
| 90 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.48976161 |
| 91 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47261065 |
| 92 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.45112429 |
| 93 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.43532301 |
| 94 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.43310618 |
| 95 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.43296175 |
| 96 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.42669496 |
| 97 | Long-term potentiation_Homo sapiens_hsa04720 | 0.42334629 |
| 98 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.41312004 |
| 99 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.39424866 |
| 100 | Endocytosis_Homo sapiens_hsa04144 | 0.39210228 |

