SPATA32

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1spermatid development (GO:0007286)9.99806366
2epithelial cilium movement (GO:0003351)9.89706768
3response to pheromone (GO:0019236)9.67768039
4plasma membrane fusion (GO:0045026)9.58895208
5axonemal dynein complex assembly (GO:0070286)9.37130801
6motile cilium assembly (GO:0044458)9.31241264
7reproduction (GO:0000003)9.13192799
8regulation of cilium movement (GO:0003352)8.81415544
9negative regulation of inclusion body assembly (GO:0090084)7.97360041
10cilium or flagellum-dependent cell motility (GO:0001539)7.90984869
11cilium movement (GO:0003341)7.89816225
12sperm capacitation (GO:0048240)7.43388177
13single fertilization (GO:0007338)7.10841862
14epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.08041460
15organic cation transport (GO:0015695)6.98521339
16synaptonemal complex organization (GO:0070193)6.93127742
17* spermatogenesis (GO:0007283)6.85599293
18synaptonemal complex assembly (GO:0007130)6.83087956
19* male gamete generation (GO:0048232)6.83060693
20microtubule depolymerization (GO:0007019)6.73947108
21regulation of inclusion body assembly (GO:0090083)6.56657471
22male meiosis (GO:0007140)6.39159171
23rRNA methylation (GO:0031167)6.30893306
24* gamete generation (GO:0007276)6.26879656
25calcium ion-dependent exocytosis (GO:0017156)6.17212852
26piRNA metabolic process (GO:0034587)6.08451771
27fertilization (GO:0009566)6.06346664
28protein targeting to Golgi (GO:0000042)5.95183620
29chromosome condensation (GO:0030261)5.85824151
30phosphatidylethanolamine biosynthetic process (GO:0006646)5.84146417
31establishment of protein localization to Golgi (GO:0072600)5.77197997
32spermatid nucleus differentiation (GO:0007289)5.63902394
33retrograde transport, vesicle recycling within Golgi (GO:0000301)5.58646940
34cellular ketone body metabolic process (GO:0046950)5.57644378
35DNA packaging (GO:0006323)5.50945831
36germ cell development (GO:0007281)5.46217915
37glycerol ether metabolic process (GO:0006662)5.40261018
38sexual reproduction (GO:0019953)5.37213332
39phosphatidylethanolamine metabolic process (GO:0046337)5.35529098
40rRNA modification (GO:0000154)5.32909283
41cellular process involved in reproduction in multicellular organism (GO:0022412)5.31679969
42regulation of microtubule-based movement (GO:0060632)5.29821474
43cell recognition (GO:0008037)5.06549451
44antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.04251313
45ventricular system development (GO:0021591)5.04073955
46centriole replication (GO:0007099)5.03936689
47ether metabolic process (GO:0018904)4.99308238
48regulation of Rab GTPase activity (GO:0032313)4.93854370
49positive regulation of Rab GTPase activity (GO:0032851)4.93854370
50* multicellular organismal reproductive process (GO:0048609)4.92420353
51ketone body metabolic process (GO:1902224)4.89861500
52microtubule severing (GO:0051013)4.88262185
53single strand break repair (GO:0000012)4.78633821
54centriole assembly (GO:0098534)4.55505862
55seminiferous tubule development (GO:0072520)4.51898850
56chromosome organization involved in meiosis (GO:0070192)4.46397371
57protein localization to Golgi apparatus (GO:0034067)4.40546317
58male meiosis I (GO:0007141)4.39567920
59left/right pattern formation (GO:0060972)4.29497163
60chaperone-mediated protein complex assembly (GO:0051131)4.19381028
61regulation of centriole replication (GO:0046599)4.07206028
62multicellular organismal development (GO:0007275)4.04210022
63regulation of transcription involved in cell fate commitment (GO:0060850)4.04107600
64negative regulation of Rho protein signal transduction (GO:0035024)3.91047281
65DNA methylation involved in gamete generation (GO:0043046)3.85753788
66meiotic nuclear division (GO:0007126)3.82500832
67sequestering of actin monomers (GO:0042989)3.73269123
68coenzyme catabolic process (GO:0009109)3.60444185
69protein K11-linked deubiquitination (GO:0035871)3.60434095
70protein polyglutamylation (GO:0018095)3.59865309
71protein refolding (GO:0042026)3.53404754
72peptidyl-threonine dephosphorylation (GO:0035970)3.47705329
73cerebral cortex neuron differentiation (GO:0021895)3.47365610
74microtubule polymerization or depolymerization (GO:0031109)3.47073513
75meiosis I (GO:0007127)3.44089554
76genitalia morphogenesis (GO:0035112)3.41981579
77glycolytic process (GO:0006096)3.39501190
78regulation of spindle checkpoint (GO:0090231)3.25048601
79nucleus organization (GO:0006997)3.21242063
80polyamine biosynthetic process (GO:0006596)3.20606327
81musculoskeletal movement (GO:0050881)3.12025759
82multicellular organismal movement (GO:0050879)3.12025759
83mitotic sister chromatid cohesion (GO:0007064)3.07321275
84regulation of somitogenesis (GO:0014807)3.07089230
85cranial nerve morphogenesis (GO:0021602)3.06543569
86positive regulation of macrophage activation (GO:0043032)3.06470050
87nucleoside diphosphate phosphorylation (GO:0006165)3.04008823
88RNA localization (GO:0006403)3.01746525
89nephron tubule morphogenesis (GO:0072078)3.01584984
90nephron epithelium morphogenesis (GO:0072088)3.01584984
91cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.01244487
92carnitine transport (GO:0015879)3.00832772
93amino-acid betaine transport (GO:0015838)3.00832772
94interferon-gamma secretion (GO:0072643)3.00211117
95chromatin silencing (GO:0006342)2.99623623
96axoneme assembly (GO:0035082)2.95732589
97meiotic cell cycle (GO:0051321)2.95664015
98negative regulation of gene expression, epigenetic (GO:0045814)2.93820671
99polyol catabolic process (GO:0046174)2.90942245
100protein localization to cilium (GO:0061512)2.89877025
101RNA destabilization (GO:0050779)2.89071351
102regulation of meiosis I (GO:0060631)2.88311976
103cellular response to pH (GO:0071467)2.88114811
104regulation of cilium assembly (GO:1902017)2.87584807
105NAD biosynthetic process (GO:0009435)2.87020204
106negative regulation of granulocyte differentiation (GO:0030853)2.84085504
107monoubiquitinated protein deubiquitination (GO:0035520)2.82905492
108mitochondrion degradation (GO:0000422)2.82532145
109positive regulation of gastrulation (GO:2000543)2.81702366
110negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.81484762
111alditol metabolic process (GO:0019400)2.81301041
112carnitine transmembrane transport (GO:1902603)2.80741265
113mesenchymal cell differentiation involved in kidney development (GO:0072161)2.78856532
114mesenchymal cell differentiation involved in renal system development (GO:2001012)2.78856532
115positive regulation of guanylate cyclase activity (GO:0031284)2.76995986
116histone H3-K9 demethylation (GO:0033169)2.75574206
117GTP biosynthetic process (GO:0006183)2.74451650
118homeostasis of number of cells within a tissue (GO:0048873)2.69117653
119microtubule-based movement (GO:0007018)2.68644217
120regulation of interleukin-13 production (GO:0032656)2.67013944
121arginine catabolic process (GO:0006527)2.66464351
122cilium organization (GO:0044782)2.65738313
123positive regulation of glycolytic process (GO:0045821)2.59037209
124cilium assembly (GO:0042384)2.56426644
125meiotic cell cycle process (GO:1903046)2.54672435
126cellular component assembly involved in morphogenesis (GO:0010927)2.53900204
127membrane protein intracellular domain proteolysis (GO:0031293)2.52800952
128negative regulation of organelle assembly (GO:1902116)2.47624843
129protein-DNA complex disassembly (GO:0032986)2.47500701
130nucleosome disassembly (GO:0006337)2.47500701
131cilium morphogenesis (GO:0060271)2.47141802
132UTP biosynthetic process (GO:0006228)2.44116251
133peptidyl-glutamic acid modification (GO:0018200)2.43814932
134protein depolymerization (GO:0051261)2.39621300
135sperm motility (GO:0030317)14.7985292
136cell wall macromolecule metabolic process (GO:0044036)13.3119876
137cell wall macromolecule catabolic process (GO:0016998)13.3119876
138acrosome reaction (GO:0007340)12.9868798
139fusion of sperm to egg plasma membrane (GO:0007342)12.5075809
140sperm-egg recognition (GO:0035036)11.4068819
141acrosome assembly (GO:0001675)11.2542481
142binding of sperm to zona pellucida (GO:0007339)10.4875322
143cell-cell recognition (GO:0009988)10.2162645
144multicellular organism reproduction (GO:0032504)10.2061550

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.30173271
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.69258806
3EZH2_22144423_ChIP-Seq_EOC_Human4.86694175
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.70161801
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.37187038
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.82642811
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.79906414
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.71076532
9VDR_22108803_ChIP-Seq_LS180_Human2.69941566
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.39273904
11GATA1_26923725_Chip-Seq_HPCs_Mouse2.36782945
12NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.19060217
13DROSHA_22980978_ChIP-Seq_HELA_Human2.18930664
14CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.14539316
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.07167595
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.00661402
17EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.00623972
18ZNF274_21170338_ChIP-Seq_K562_Hela1.98371211
19ERA_21632823_ChIP-Seq_H3396_Human1.93650762
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.93445117
21RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.88482938
22NANOG_20526341_ChIP-Seq_ESCs_Human1.87349430
23RAC3_21632823_ChIP-Seq_H3396_Human1.83218063
24MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.80641082
25VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.77300944
26EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.75841437
27KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.74863603
28BCL6_27268052_Chip-Seq_Bcells_Human1.73876926
29FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72562005
30FLI1_27457419_Chip-Seq_LIVER_Mouse1.71554688
31ELK4_26923725_Chip-Seq_MESODERM_Mouse1.71201960
32SOX2_22085726_ChIP-Seq_NPCs_Mouse1.66864079
33TDRD3_21172665_ChIP-Seq_MCF-7_Human1.66118426
34TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.66108640
35STAT1_17558387_ChIP-Seq_HELA_Human1.65065891
36CTCF_27219007_Chip-Seq_Bcells_Human1.64056851
37E2F1_20622854_ChIP-Seq_HELA_Human1.64040901
38MYC_19829295_ChIP-Seq_ESCs_Human1.63480508
39REST_21632747_ChIP-Seq_MESCs_Mouse1.61301408
40TAF2_19829295_ChIP-Seq_ESCs_Human1.58768474
41FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.57434365
42ER_23166858_ChIP-Seq_MCF-7_Human1.54033583
43GATA3_21867929_ChIP-Seq_CD8_Mouse1.53376553
44GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.51501549
45PHF8_20622854_ChIP-Seq_HELA_Human1.50668101
46SMC4_20622854_ChIP-Seq_HELA_Human1.47892070
47P68_20966046_ChIP-Seq_HELA_Human1.46700354
48WDR5_24793694_ChIP-Seq_LNCAP_Human1.45836171
49PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.45412901
50KDM2B_26808549_Chip-Seq_REH_Human1.45401399
51RUNX_20019798_ChIP-Seq_JUKART_Human1.44981001
52FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.43896830
53FUS_26573619_Chip-Seq_HEK293_Human1.42713095
54OCT4_20526341_ChIP-Seq_ESCs_Human1.41953155
55IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40548298
56CBP_20019798_ChIP-Seq_JUKART_Human1.40548298
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.39536149
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.37735977
59P300_27268052_Chip-Seq_Bcells_Human1.36801849
60TAL1_26923725_Chip-Seq_HPCs_Mouse1.36520420
61AUTS2_25519132_ChIP-Seq_293T-REX_Human1.36231828
62GATA3_21878914_ChIP-Seq_MCF-7_Human1.35683040
63SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.35292823
64RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.34993689
65LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.34324276
66P53_21459846_ChIP-Seq_SAOS-2_Human1.34119398
67SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.33161489
68CTBP2_25329375_ChIP-Seq_LNCAP_Human1.32104208
69TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30174942
70TP63_22573176_ChIP-Seq_HFKS_Human1.28203882
71EZH2_27294783_Chip-Seq_ESCs_Mouse1.28155185
72SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.27272422
73ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.25974184
74GATA3_21867929_ChIP-Seq_TH1_Mouse1.25162597
75CBX2_27304074_Chip-Seq_ESCs_Mouse1.24848244
76TAF15_26573619_Chip-Seq_HEK293_Human1.24767930
77PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23384019
78RAD21_21589869_ChIP-Seq_MESCs_Mouse1.22764767
79GF1_26923725_Chip-Seq_HPCs_Mouse1.22734028
80FLI1_21867929_ChIP-Seq_TH2_Mouse1.21572437
81MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20410904
82LXR_22292898_ChIP-Seq_THP-1_Human1.19727968
83CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17937818
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.17709951
85KAP1_22055183_ChIP-Seq_ESCs_Mouse1.17323636
86AR_25329375_ChIP-Seq_VCAP_Human1.17219103
87CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17148521
88SMRT_27268052_Chip-Seq_Bcells_Human1.16932585
89TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16636992
90POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16636992
91EZH2_27304074_Chip-Seq_ESCs_Mouse1.16508795
92HNFA_21074721_ChIP-Seq_CACO-2_Human1.16068790
93SA1_27219007_Chip-Seq_Bcells_Human1.15404125
94SPI1_26923725_Chip-Seq_HPCs_Mouse1.14515848
95RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.14471060
96RBPJ_21746931_ChIP-Seq_IB4_Human1.13623068
97SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13486936
98CBX2_22325352_ChIP-Seq_293T-Rex_Human1.13434055
99CEBPB_22108803_ChIP-Seq_LS180_Human1.13037725
100P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.13035400
101BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12675624
102TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.12530639
103GATA1_19941827_ChIP-Seq_MEL86_Mouse1.09920943
104ETV1_20927104_ChIP-Seq_GIST48_Human1.09902502
105PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.09832438
106MYC_27129775_Chip-Seq_CORNEA_Mouse1.09712383
107SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08524515
108CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.08281153
109TET1_21451524_ChIP-Seq_MESCs_Mouse1.08238335
110NFIB_24661679_ChIP-Seq_LUNG_Mouse1.07658597
111JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.07551707
112SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.06421385
113ERG_20517297_ChIP-Seq_VCAP_Human1.05555666
114RXRA_24833708_ChIP-Seq_LIVER_Mouse1.05387772
115YY1_22570637_ChIP-Seq_MALME-3M_Human1.05297805
116RUNX1_26923725_Chip-Seq_HPCs_Mouse1.04883643
117NFE2_27457419_Chip-Seq_LIVER_Mouse1.04472807
118KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04376509
119P300_19829295_ChIP-Seq_ESCs_Human1.03453039
120FOXA1_25329375_ChIP-Seq_VCAP_Human1.03248458
121FOXA1_27270436_Chip-Seq_PROSTATE_Human1.03248458
122EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.02351595
123HOXB7_26014856_ChIP-Seq_BT474_Human1.01272790
124EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.01120808
125CTCF_20526341_ChIP-Seq_ESCs_Human1.01097702
126ESET_19884257_ChIP-Seq_ESCs_Mouse1.00824694
127TBL1_22424771_ChIP-Seq_293T_Human1.00718688
128SMAD3_21741376_ChIP-Seq_EPCs_Human1.00541680
129RUNX2_22187159_ChIP-Seq_PCA_Human0.98984066
130PHF8_20622853_ChIP-Seq_HELA_Human0.98842198
131PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.98783572
132GATA6_21074721_ChIP-Seq_CACO-2_Human0.97860017
133PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.97480178
134NCOR_22424771_ChIP-Seq_293T_Human0.96980943
135SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96758500
136FOXH1_21741376_ChIP-Seq_ESCs_Human0.96586487
137MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.96105917
138SUZ12_27294783_Chip-Seq_ESCs_Mouse0.96068327
139NANOG_19829295_ChIP-Seq_ESCs_Human0.96022769
140SOX2_19829295_ChIP-Seq_ESCs_Human0.96022769
141NANOG_18555785_Chip-Seq_ESCs_Mouse0.95489470
142RARA_24833708_ChIP-Seq_LIVER_Mouse0.95214294
143SUZ12_27294783_Chip-Seq_NPCs_Mouse0.94337961
144KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.94331825
145REST_18959480_ChIP-ChIP_MESCs_Mouse0.93893350
146ELF1_20517297_ChIP-Seq_JURKAT_Human0.93369980
147CRX_20693478_ChIP-Seq_RETINA_Mouse0.93232636
148PCGF2_27294783_Chip-Seq_NPCs_Mouse0.92942974
149CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.92710086
150SOX11_22085726_ChIP-Seq_ESNs_Mouse0.92422065
151BCOR_27268052_Chip-Seq_Bcells_Human0.92331520
152ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.91949165
153SMC3_22415368_ChIP-Seq_MEFs_Mouse0.91616319
154PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90613035
155NFYB_21822215_ChIP-Seq_K562_Human0.90007498
156LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.89366280
157TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89127418
158SMAD4_21741376_ChIP-Seq_EPCs_Human0.88546199
159ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88375466
160SOX9_26525672_Chip-Seq_HEART_Mouse0.88276023
161FLI1_21867929_ChIP-Seq_CD8_Mouse0.88196200
162OCT1_27270436_Chip-Seq_PROSTATE_Human0.87970707
163SMAD3_21741376_ChIP-Seq_ESCs_Human0.87942741

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.01547110
2MP0001929_abnormal_gametogenesis5.42039175
3MP0008877_abnormal_DNA_methylation3.60823543
4MP0002161_abnormal_fertility/fecundity3.29079544
5MP0002210_abnormal_sex_determination3.12687448
6MP0005670_abnormal_white_adipose3.02220725
7MP0001145_abnormal_male_reproductive2.64577357
8MP0005379_endocrine/exocrine_gland_phen2.35320547
9MP0001485_abnormal_pinna_reflex2.34297643
10MP0000653_abnormal_sex_gland2.27115703
11MP0000678_abnormal_parathyroid_gland2.15588694
12MP0005410_abnormal_fertilization16.6826592
13MP0002653_abnormal_ependyma_morphology1.99177544
14MP0003718_maternal_effect1.73938477
15MP0002132_abnormal_respiratory_system1.59166941
16MP0006292_abnormal_olfactory_placode1.54221721
17MP0001963_abnormal_hearing_physiology1.45762245
18MP0003646_muscle_fatigue1.45383879
19MP0004233_abnormal_muscle_weight1.41214814
20MP0005645_abnormal_hypothalamus_physiol1.40771452
21MP0002160_abnormal_reproductive_system1.34868935
22MP0000026_abnormal_inner_ear1.34552458
23MP0002138_abnormal_hepatobiliary_system1.32326314
24MP0005623_abnormal_meninges_morphology1.23894755
25MP0002249_abnormal_larynx_morphology1.22883531
26MP0008789_abnormal_olfactory_epithelium1.19978133
27MP0001765_abnormal_ion_homeostasis1.17124398
28MP0005310_abnormal_salivary_gland1.14274386
29MP0002163_abnormal_gland_morphology1.12535447
30MP0005394_taste/olfaction_phenotype1.10135523
31MP0005499_abnormal_olfactory_system1.10135523
32MP0001984_abnormal_olfaction1.09624746
33MP0009046_muscle_twitch1.07904855
34MP0009053_abnormal_anal_canal1.07397781
35MP0002736_abnormal_nociception_after1.06309996
36MP0002234_abnormal_pharynx_morphology1.01909671
37MP0002282_abnormal_trachea_morphology1.01293144
38MP0003172_abnormal_lysosome_physiology0.95309263
39MP0003880_abnormal_central_pattern0.93375475
40MP0001905_abnormal_dopamine_level0.91845750
41MP0001968_abnormal_touch/_nociception0.88273375
42MP0000049_abnormal_middle_ear0.80268244
43MP0003329_amyloid_beta_deposits0.78347139
44MP0002127_abnormal_cardiovascular_syste0.77800538
45MP0001970_abnormal_pain_threshold0.76681830
46MP0005167_abnormal_blood-brain_barrier0.74275761
47MP0001501_abnormal_sleep_pattern0.72560869
48MP0005395_other_phenotype0.72322150
49MP0000015_abnormal_ear_pigmentation0.71382192
50MP0004270_analgesia0.71366405
51MP0003136_yellow_coat_color0.69964301
52MP0003115_abnormal_respiratory_system0.69337747
53MP0000470_abnormal_stomach_morphology0.65842342
54MP0005636_abnormal_mineral_homeostasis0.65768789
55MP0000778_abnormal_nervous_system0.65414935
56MP0004085_abnormal_heartbeat0.64944881
57MP0005647_abnormal_sex_gland0.64279893
58MP0005083_abnormal_biliary_tract0.63410955
59MP0005174_abnormal_tail_pigmentation0.63244674
60MP0001727_abnormal_embryo_implantation0.62417205
61MP0002184_abnormal_innervation0.60023070
62MP0005248_abnormal_Harderian_gland0.59937222
63MP0005389_reproductive_system_phenotype0.59482839
64MP0003137_abnormal_impulse_conducting0.58693356
65MP0009764_decreased_sensitivity_to0.58607515
66MP0004859_abnormal_synaptic_plasticity0.58313222
67MP0003635_abnormal_synaptic_transmissio0.57892437
68MP0004811_abnormal_neuron_physiology0.57828059
69MP0008995_early_reproductive_senescence0.57110938
70MP0005666_abnormal_adipose_tissue0.56905172
71MP0000569_abnormal_digit_pigmentation0.55841167
72MP0005423_abnormal_somatic_nervous0.55501563
73MP0005195_abnormal_posterior_eye0.55137024
74MP0000681_abnormal_thyroid_gland0.54937836
75MP0003123_paternal_imprinting0.54486557
76MP0005084_abnormal_gallbladder_morpholo0.54035859
77MP0003879_abnormal_hair_cell0.53770425
78MP0005377_hearing/vestibular/ear_phenot0.52672165
79MP0003878_abnormal_ear_physiology0.52672165
80MP0001324_abnormal_eye_pigmentation0.52552753
81MP0000631_abnormal_neuroendocrine_gland0.51310611
82MP0002752_abnormal_somatic_nervous0.51264635
83MP0000230_abnormal_systemic_arterial0.50912273
84MP0001879_abnormal_lymphatic_vessel0.50444119
85MP0002095_abnormal_skin_pigmentation0.50156607
86MP0003936_abnormal_reproductive_system0.50068727
87MP0008058_abnormal_DNA_repair0.49881186
88MP0010329_abnormal_lipoprotein_level0.49207580
89MP0004036_abnormal_muscle_relaxation0.48573143
90MP0006276_abnormal_autonomic_nervous0.48126456
91MP0001764_abnormal_homeostasis0.47137720
92MP0002063_abnormal_learning/memory/cond0.46909416
93MP0009384_cardiac_valve_regurgitation0.46692269
94MP0000427_abnormal_hair_cycle0.46504930
95MP0000534_abnormal_ureter_morphology0.46244336
96MP0000604_amyloidosis0.45923994
97MP0002272_abnormal_nervous_system0.45268403
98MP0003633_abnormal_nervous_system0.45200526
99MP0002572_abnormal_emotion/affect_behav0.45180189
100MP0002269_muscular_atrophy0.44197196
101MP0003787_abnormal_imprinting0.44054664
102MP0003011_delayed_dark_adaptation0.43259932
103MP0008569_lethality_at_weaning0.42990767
104MP0005551_abnormal_eye_electrophysiolog0.41801740
105MP0000358_abnormal_cell_content/0.41473117
106MP0002909_abnormal_adrenal_gland0.40876673
107MP0005253_abnormal_eye_physiology0.39497674
108MP0003699_abnormal_female_reproductive0.38860696
109MP0004742_abnormal_vestibular_system0.38379647
110MP0006036_abnormal_mitochondrial_physio0.36897064
111MP0001293_anophthalmia0.36870170
112MP0003631_nervous_system_phenotype0.36335270
113MP0002822_catalepsy0.36208672
114MP0009745_abnormal_behavioral_response0.35903569
115MP0002152_abnormal_brain_morphology0.34747463
116MP0009115_abnormal_fat_cell0.33249474
117MP0002064_seizures0.32757603
118MP0003942_abnormal_urinary_system0.31986855
119MP0001440_abnormal_grooming_behavior0.30625123
120MP0002169_no_abnormal_phenotype0.30093576
121MP0002873_normal_phenotype0.29981822
122MP0002928_abnormal_bile_duct0.29313893
123MP0001545_abnormal_hematopoietic_system0.29253657
124MP0005397_hematopoietic_system_phenotyp0.29253657
125MP0003861_abnormal_nervous_system0.28516434
126MP0001486_abnormal_startle_reflex0.28433869
127MP0000751_myopathy0.28324429
128MP0006035_abnormal_mitochondrial_morpho0.26045128
129MP0004145_abnormal_muscle_electrophysio0.26042011
130MP0002734_abnormal_mechanical_nocicepti0.25559409
131MP0003948_abnormal_gas_homeostasis0.25468413
132MP0001529_abnormal_vocalization0.25402312
133MP0002067_abnormal_sensory_capabilities0.24977185
134MP0000955_abnormal_spinal_cord0.24907639
135MP0005391_vision/eye_phenotype0.24518807
136MP0009278_abnormal_bone_marrow0.24335981
137MP0002229_neurodegeneration0.24161133
138MP0001502_abnormal_circadian_rhythm0.24157548
139MP0002735_abnormal_chemical_nociception0.23933286
140MP0008961_abnormal_basal_metabolism0.23913677
141MP0004133_heterotaxia0.23893249
142MP0002102_abnormal_ear_morphology0.23663202
143MP0002557_abnormal_social/conspecific_i0.23594652
144MP0002882_abnormal_neuron_morphology0.22806185
145MP0002971_abnormal_brown_adipose0.22604756
146MP0000920_abnormal_myelination0.21785639
147MP0001348_abnormal_lacrimal_gland0.21597762
148MP0002066_abnormal_motor_capabilities/c0.21161367
149MP0005535_abnormal_body_temperature0.20745323
150MP0001986_abnormal_taste_sensitivity0.18891876
151MP0000001_mammalian_phenotype0.18339544
152MP0002733_abnormal_thermal_nociception0.17648055

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.32895411
2Abnormal respiratory motile cilium morphology (HP:0005938)9.32895411
3Abnormal respiratory motile cilium physiology (HP:0012261)9.15293294
4Severe visual impairment (HP:0001141)8.56032331
5Infertility (HP:0000789)7.22646038
6Rhinitis (HP:0012384)7.22186377
7Chronic bronchitis (HP:0004469)7.19962294
8Abnormal ciliary motility (HP:0012262)7.13392066
9Nasal polyposis (HP:0100582)6.28803532
10Attenuation of retinal blood vessels (HP:0007843)5.51741594
11Abnormality of the nasal mucosa (HP:0000433)5.15474838
12Male infertility (HP:0003251)5.10372656
13Bony spicule pigmentary retinopathy (HP:0007737)4.72283841
14Bronchitis (HP:0012387)4.50013963
15Bronchiectasis (HP:0002110)4.26197976
16Abnormal rod and cone electroretinograms (HP:0008323)4.00524181
17Chronic hepatic failure (HP:0100626)3.97365246
18Hyperkalemia (HP:0002153)3.94380605
19Nephronophthisis (HP:0000090)3.93746439
20Abnormal spermatogenesis (HP:0008669)3.65371483
21Potter facies (HP:0002009)3.61043981
22Facial shape deformation (HP:0011334)3.61043981
23Enlarged epiphyses (HP:0010580)3.50199357
24Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.37524345
25Hypoplastic ischia (HP:0003175)3.32372784
26Abnormality of macular pigmentation (HP:0008002)3.26326110
27Recurrent otitis media (HP:0000403)3.24293355
28Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.20361288
29Recurrent sinusitis (HP:0011108)3.12763314
30Abnormality of the aortic arch (HP:0012303)2.98072982
31Resting tremor (HP:0002322)2.95076442
32Abnormality of the renal medulla (HP:0100957)2.90485697
33Aplasia/Hypoplasia of the earlobes (HP:0009906)2.88243095
34Abnormality of the ischium (HP:0003174)2.82558345
35Cholecystitis (HP:0001082)2.81203043
36Abnormal gallbladder physiology (HP:0012438)2.81203043
37Cone-rod dystrophy (HP:0000548)2.77785234
38Recurrent bronchitis (HP:0002837)2.70048409
39Impulsivity (HP:0100710)2.65037095
40Tubulointerstitial nephritis (HP:0001970)2.64069306
41Abnormality of the parathyroid morphology (HP:0011766)2.45304716
42Tubular atrophy (HP:0000092)2.44817408
43Hypoplasia of the thymus (HP:0000778)2.44634961
44Unilateral renal agenesis (HP:0000122)2.41468017
45Polyuria (HP:0000103)2.40121294
46Molar tooth sign on MRI (HP:0002419)2.39219059
47Abnormality of midbrain morphology (HP:0002418)2.39219059
48Gonadotropin excess (HP:0000837)2.38810350
49Abnormality of potassium homeostasis (HP:0011042)2.36671942
50Pendular nystagmus (HP:0012043)2.35844320
51Abnormality of dental color (HP:0011073)2.33380949
52Amblyopia (HP:0000646)2.31972041
53Dyschromatopsia (HP:0007641)2.30197864
54Tubulointerstitial abnormality (HP:0001969)2.26354590
55Recurrent pneumonia (HP:0006532)2.23840167
56Medial flaring of the eyebrow (HP:0010747)2.18948020
57Epiphyseal dysplasia (HP:0002656)2.18135461
58Choroideremia (HP:0001139)2.16232995
59Renal Fanconi syndrome (HP:0001994)2.15754855
60Amelogenesis imperfecta (HP:0000705)2.15754775
61Hyperthyroidism (HP:0000836)2.15427453
62Widely patent fontanelles and sutures (HP:0004492)2.15020902
63Postural instability (HP:0002172)2.14777267
64Azoospermia (HP:0000027)2.12833957
65Abnormal albumin level (HP:0012116)2.06437005
66Hypoalbuminemia (HP:0003073)2.06437005
67Generalized aminoaciduria (HP:0002909)2.06358224
68Spastic tetraparesis (HP:0001285)2.04972233
69Abnormality of the costochondral junction (HP:0000919)2.04619002
70Hypophosphatemic rickets (HP:0004912)2.04152167
71Decreased central vision (HP:0007663)2.03780327
72Tetany (HP:0001281)2.01577908
73Absent/shortened dynein arms (HP:0200106)13.5722337
74Dynein arm defect of respiratory motile cilia (HP:0012255)13.5722337
75Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.6426646
76Portal hypertension (HP:0001409)1.96690694
77Neurofibrillary tangles (HP:0002185)1.95543126
78Pigmentary retinal degeneration (HP:0001146)1.92206048
79Myokymia (HP:0002411)1.92144295
80Abnormality of the pubic bones (HP:0003172)1.88742250
81Photophobia (HP:0000613)1.88340652
82Insulin-resistant diabetes mellitus (HP:0000831)1.87342365
83Abnormality of the hepatic vasculature (HP:0006707)1.86951031
84Bulbous nose (HP:0000414)1.86766966
85Double outlet right ventricle (HP:0001719)1.86333525
86Congenital malformation of the right heart (HP:0011723)1.86333525
87Hypoalphalipoproteinemia (HP:0003233)1.85311770
88Progressive sensorineural hearing impairment (HP:0000408)1.84903436
89Agitation (HP:0000713)1.83467804
90Tubulointerstitial fibrosis (HP:0005576)1.82858215
91Congenital stationary night blindness (HP:0007642)1.81973833
92Sclerocornea (HP:0000647)1.81290382
93Hemorrhage of the eye (HP:0011885)1.80258730
94Abnormality of urine glucose concentration (HP:0011016)1.79088482
95Glycosuria (HP:0003076)1.79088482
96Heterotopia (HP:0002282)1.76010268
97Hyponatremia (HP:0002902)1.73782818
98Decreased electroretinogram (ERG) amplitude (HP:0000654)1.73293072
99Renovascular hypertension (HP:0100817)1.73263245
100Pancreatic fibrosis (HP:0100732)1.70000416
101Type II diabetes mellitus (HP:0005978)1.69470755
102Pancreatic cysts (HP:0001737)1.67963903
103Polydipsia (HP:0001959)1.67585654
104Abnormal drinking behavior (HP:0030082)1.67585654
105Retinal atrophy (HP:0001105)1.66192829
106Bile duct proliferation (HP:0001408)1.65098902
107Abnormal biliary tract physiology (HP:0012439)1.65098902
108Genetic anticipation (HP:0003743)1.64581356
109Asymmetric septal hypertrophy (HP:0001670)1.64265666
110Abnormality of the femoral head (HP:0003368)1.64253739
111Cerebral inclusion bodies (HP:0100314)1.63920638
112Bundle branch block (HP:0011710)1.61371032
113Stage 5 chronic kidney disease (HP:0003774)1.59013958
114Abnormality of renal excretion (HP:0011036)1.55370447
115Postaxial foot polydactyly (HP:0001830)1.54567830
116Hypoplasia of the capital femoral epiphysis (HP:0003090)1.50708252
117Sensory axonal neuropathy (HP:0003390)1.50337383
118Bell-shaped thorax (HP:0001591)1.48966808
119Exercise-induced myalgia (HP:0003738)1.48125178
120Oculomotor apraxia (HP:0000657)1.46832104
121Hemiparesis (HP:0001269)1.46572867
122Aplasia/Hypoplasia of the lens (HP:0008063)1.46270388
123Congenital hepatic fibrosis (HP:0002612)1.43541256
124Easy fatigability (HP:0003388)1.42393189
125Neoplasm of the heart (HP:0100544)1.41622160
126Constricted visual fields (HP:0001133)1.41416287
127Short ribs (HP:0000773)1.39341369
128Abnormality of the renal cortex (HP:0011035)1.37445915
129Abnormality of the neuromuscular junction (HP:0003398)1.36197268
130Fatigable weakness (HP:0003473)1.36197268
131Loss of speech (HP:0002371)1.34597911
132Abnormality of permanent molar morphology (HP:0011071)1.33679898
133Abnormality of the dental root (HP:0006486)1.33679898
134Taurodontia (HP:0000679)1.33679898
135Abnormal urine output (HP:0012590)1.32579583
136Progressive cerebellar ataxia (HP:0002073)1.32546387
137Myoglobinuria (HP:0002913)1.32282929
138Hypercholesterolemia (HP:0003124)1.30338872
139Deformed sella turcica (HP:0002681)1.30044921
140Abnormality of dentin (HP:0010299)1.29435825
141Renal dysplasia (HP:0000110)1.29344168
142Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.29188885
143Postaxial hand polydactyly (HP:0001162)1.28917662
144Abnormality of ocular smooth pursuit (HP:0000617)1.27190837
145Truncal obesity (HP:0001956)1.26931525
146Abnormality of the dental pulp (HP:0006479)1.25513040
147Abnormality of saccadic eye movements (HP:0000570)1.25054795
148Amyotrophic lateral sclerosis (HP:0007354)1.22534834
149Retinal dysplasia (HP:0007973)1.22241876
150Abnormality of molar (HP:0011077)1.21569290
151Abnormality of molar morphology (HP:0011070)1.21569290
152Abnormality of the lower motor neuron (HP:0002366)1.20822735
153Polymicrogyria (HP:0002126)1.20040213
154Decreased muscle mass (HP:0003199)1.19743186
155Cystic liver disease (HP:0006706)1.19151822
156Chronic sinusitis (HP:0011109)1.18891903
157Dysmetric saccades (HP:0000641)1.18630997
158Facial cleft (HP:0002006)1.18124761
159Broad distal phalanx of finger (HP:0009836)1.17708200
160Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.17339223
161Absent epiphyses (HP:0010577)1.17339223
162Exercise-induced muscle cramps (HP:0003710)1.15925974

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.85885355
2PDK47.85885355
3PLK47.20763702
4TESK16.58938897
5PRKD35.53735597
6PDK25.02628084
7ICK4.77547066
8INSRR3.99431760
9DDR23.83940224
10MAP4K23.60714028
11PLK22.76614919
12TAOK32.67274081
13BRD42.35161268
14PTK2B2.12674830
15STK162.08161389
16WNK42.06119500
17STK392.01007570
18STK381.90684133
19PNCK1.82105548
20DYRK1B1.78233584
21NEK21.46078837
22MAP3K91.36075732
23PDK11.33577808
24PIK3CG1.28917012
25RIPK41.19027648
26MST1R1.07376780
27TXK1.07361184
28NLK0.95560382
29FRK0.94141588
30TYRO30.92133690
31PDPK10.91287618
32ZAK0.90589051
33CDK70.88054879
34SIK20.87903232
35DYRK30.80816689
36MAPK130.80553391
37WNK10.80415258
38ADRBK20.78951576
39MAP2K20.77109882
40MAPK150.74671547
41CDK120.74254224
42TLK10.71656158
43NTRK20.71128719
44EEF2K0.70128335
45MAP3K110.66574827
46IRAK10.66215199
47RPS6KA20.66169846
48PINK10.62513983
49MAPKAPK50.62483957
50PRKAA20.62026484
51CCNB10.60958519
52MAP2K60.58703001
53CAMK1G0.58640456
54CAMK1D0.58242368
55GRK70.56702104
56TESK20.56486297
57NUAK10.56174999
58PHKG20.56051829
59PHKG10.56051829
60CDK30.53198986
61PRKCG0.51300542
62BMPR1B0.50521014
63PASK0.49177675
64LATS10.48830342
65MUSK0.47875055
66CAMKK10.46800595
67CDK40.46709099
68IKBKB0.46160565
69KSR20.44631039
70LMTK20.44021180
71CHEK20.42582576
72GRK60.40901072
73TNK20.39634563
74MARK20.38120117
75PAK10.37878428
76IRAK20.37372884
77CHUK0.36615902
78WNK30.36598015
79UHMK10.35812703
80MAP3K100.35735691
81AKT30.35181597
82DYRK20.34430698
83MAPK110.34002784
84RPS6KA60.33833381
85TTK0.33233964
86STK30.33103976
87MAPK10.32936723
88SYK0.32776121
89CDK150.31583602
90MAP3K80.31243550
91BLK0.30121173
92TIE10.29809682
93PRKCZ0.29535069
94EPHA30.29410973
95CDK180.29204165
96CHEK10.28972330
97MARK10.28940846
98ROCK10.27374647
99PAK20.27188904
100CDK11A0.26027027
101SGK2230.24161933
102SGK4940.24161933
103RPS6KC10.23997414
104RPS6KL10.23997414
105CDK140.22977383
106MAP4K10.22002497
107MAP3K20.21837523
108ACVR1B0.20816996
109MAPK140.20341667
110CAMK40.19096039
111PRKCQ0.18957958
112KIT0.18515294
113PRKCE0.17689746
114MTOR0.17670703
115ATM0.17172520
116PAK60.17111106
117PRKAA10.16897934
118STK38L0.15414656
119PAK40.14492177
120NEK60.14060240
121RPS6KB10.13950270
122MINK10.12943517
123BRSK10.12628087
124CAMK2A0.12466906
125STK110.11718695
126BRAF0.11683042
127RPS6KA10.11595386
128PRKG20.11346327
129MARK30.09852922
130GSK3B0.08848069
131MAP3K40.08489558
132CDK50.07752100
133TNIK0.07702379
134ATR0.07187766
135PKN10.06960563
136PRKCD0.06526454
137CAMK10.05868349
138MAP3K10.05460142
139PRKCB0.04861302
140MAPK80.04560384
141PRKACG0.04346398
142CSNK2A10.04080372
143BRSK20.03925626
144PRKG10.03159890
145PRKCA0.03027465
146RPS6KA30.02325633
147NTRK30.01775695
148CDC70.01460336
149WEE10.00437341
150CSNK1D0.00105822
151PLK1-0.0285639
152MAP3K5-0.0227776
153DAPK2-0.0223060
154YES1-0.0221182
155CDK1-0.0164613
156PRKACB-0.0157895
157PIM1-0.0121371
158CSNK2A2-0.0087084
159GRK5-0.0077294
160CSF1R-0.0060254
161CDK2-0.0044577
162PRKACA-0.0043042
163EPHA4-0.0002885

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000726.87896503
2Fatty acid biosynthesis_Homo sapiens_hsa000614.81433701
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.38296189
4Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.30637363
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.03561001
6Linoleic acid metabolism_Homo sapiens_hsa005912.96549633
7Pyruvate metabolism_Homo sapiens_hsa006202.92856862
8Vitamin B6 metabolism_Homo sapiens_hsa007502.73663036
9Carbohydrate digestion and absorption_Homo sapiens_hsa049732.64101656
10Glucagon signaling pathway_Homo sapiens_hsa049222.49424728
11Allograft rejection_Homo sapiens_hsa053302.42331126
12Autoimmune thyroid disease_Homo sapiens_hsa053202.40854671
13Graft-versus-host disease_Homo sapiens_hsa053322.37273610
14Type I diabetes mellitus_Homo sapiens_hsa049402.35912449
15Butanoate metabolism_Homo sapiens_hsa006502.30431288
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.26345822
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.14040584
18Propanoate metabolism_Homo sapiens_hsa006402.00582089
19Amphetamine addiction_Homo sapiens_hsa050311.91630882
20Phototransduction_Homo sapiens_hsa047441.90856293
21Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.89582879
22Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.84913381
23Glycerolipid metabolism_Homo sapiens_hsa005611.79952810
24Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.76461318
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.75980425
26Glycerophospholipid metabolism_Homo sapiens_hsa005641.73712260
27Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.71774507
28Mineral absorption_Homo sapiens_hsa049781.67976623
29PPAR signaling pathway_Homo sapiens_hsa033201.64713137
30Basal transcription factors_Homo sapiens_hsa030221.60504214
31Oocyte meiosis_Homo sapiens_hsa041141.60030945
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.57413003
33Fructose and mannose metabolism_Homo sapiens_hsa000511.55169683
34Cardiac muscle contraction_Homo sapiens_hsa042601.53518531
35Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.49062518
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.48333514
37Ether lipid metabolism_Homo sapiens_hsa005651.45625300
38Selenocompound metabolism_Homo sapiens_hsa004501.44570153
39Collecting duct acid secretion_Homo sapiens_hsa049661.44392954
40Phenylalanine metabolism_Homo sapiens_hsa003601.43423767
41Fat digestion and absorption_Homo sapiens_hsa049751.39156120
42Dorso-ventral axis formation_Homo sapiens_hsa043201.38258032
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.30889640
44Viral myocarditis_Homo sapiens_hsa054161.30258487
45Synaptic vesicle cycle_Homo sapiens_hsa047211.28891818
46Fatty acid metabolism_Homo sapiens_hsa012121.28523551
47Morphine addiction_Homo sapiens_hsa050321.26743597
48Insulin secretion_Homo sapiens_hsa049111.25558971
49Glycosaminoglycan degradation_Homo sapiens_hsa005311.23628407
50Renin secretion_Homo sapiens_hsa049241.23094516
51Long-term potentiation_Homo sapiens_hsa047201.19931597
52Fatty acid degradation_Homo sapiens_hsa000711.15292201
53Carbon metabolism_Homo sapiens_hsa012001.14902741
54Nitrogen metabolism_Homo sapiens_hsa009101.14453559
55Intestinal immune network for IgA production_Homo sapiens_hsa046721.10998201
56Pentose phosphate pathway_Homo sapiens_hsa000301.06794882
57Hedgehog signaling pathway_Homo sapiens_hsa043401.05934525
58Primary immunodeficiency_Homo sapiens_hsa053401.03658257
59Salivary secretion_Homo sapiens_hsa049700.98993034
60Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.96952501
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95488309
62Thyroid hormone synthesis_Homo sapiens_hsa049180.95324611
63Estrogen signaling pathway_Homo sapiens_hsa049150.94772564
64Antigen processing and presentation_Homo sapiens_hsa046120.92557606
65Huntingtons disease_Homo sapiens_hsa050160.89072096
66Bile secretion_Homo sapiens_hsa049760.86281060
67Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.85560384
68Pancreatic secretion_Homo sapiens_hsa049720.85459520
69Purine metabolism_Homo sapiens_hsa002300.85421367
70Gastric acid secretion_Homo sapiens_hsa049710.83844698
71Arginine and proline metabolism_Homo sapiens_hsa003300.83359076
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82805158
73Arginine biosynthesis_Homo sapiens_hsa002200.82560593
74Adipocytokine signaling pathway_Homo sapiens_hsa049200.81247018
75cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80643487
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78555527
77Cysteine and methionine metabolism_Homo sapiens_hsa002700.78549228
78Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.76441976
79Circadian entrainment_Homo sapiens_hsa047130.75794369
80Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73814418
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.71120868
82Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.70898176
83Calcium signaling pathway_Homo sapiens_hsa040200.70076083
84Glutathione metabolism_Homo sapiens_hsa004800.69270052
85Cocaine addiction_Homo sapiens_hsa050300.68029511
86mRNA surveillance pathway_Homo sapiens_hsa030150.67864546
87MAPK signaling pathway_Homo sapiens_hsa040100.66335765
88Arachidonic acid metabolism_Homo sapiens_hsa005900.64527680
89Biosynthesis of amino acids_Homo sapiens_hsa012300.64154988
90B cell receptor signaling pathway_Homo sapiens_hsa046620.63657895
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.62894511
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61550817
93Serotonergic synapse_Homo sapiens_hsa047260.61434250
94Chemical carcinogenesis_Homo sapiens_hsa052040.60651330
95Glutamatergic synapse_Homo sapiens_hsa047240.60032256
96Central carbon metabolism in cancer_Homo sapiens_hsa052300.59215878
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.58792319
98Retinol metabolism_Homo sapiens_hsa008300.58143371
99Endocytosis_Homo sapiens_hsa041440.57421205
100Legionellosis_Homo sapiens_hsa051340.56951254
101Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.54870337
102Primary bile acid biosynthesis_Homo sapiens_hsa001200.54558422
103Taste transduction_Homo sapiens_hsa047420.53756985
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53482188
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53349649
106cAMP signaling pathway_Homo sapiens_hsa040240.51609710
107Tyrosine metabolism_Homo sapiens_hsa003500.51544952
108Influenza A_Homo sapiens_hsa051640.47474035
109Nicotine addiction_Homo sapiens_hsa050330.46812270
110AMPK signaling pathway_Homo sapiens_hsa041520.45746000
111Asthma_Homo sapiens_hsa053100.44911371
112Cholinergic synapse_Homo sapiens_hsa047250.44526664
113Protein digestion and absorption_Homo sapiens_hsa049740.43370360
114Regulation of autophagy_Homo sapiens_hsa041400.42986150
115Dopaminergic synapse_Homo sapiens_hsa047280.42649621
116Inositol phosphate metabolism_Homo sapiens_hsa005620.42405731
117Alcoholism_Homo sapiens_hsa050340.41729635
118VEGF signaling pathway_Homo sapiens_hsa043700.41662288
119Renin-angiotensin system_Homo sapiens_hsa046140.40903207
120Fanconi anemia pathway_Homo sapiens_hsa034600.40154152
121Olfactory transduction_Homo sapiens_hsa047400.38821252
122GABAergic synapse_Homo sapiens_hsa047270.38545719
123Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.37722021
124Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37595916
125Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.37258698
126RNA transport_Homo sapiens_hsa030130.35819127
127Jak-STAT signaling pathway_Homo sapiens_hsa046300.34827716
128Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32726293
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.32201442
130Aldosterone synthesis and secretion_Homo sapiens_hsa049250.32173958
131Tryptophan metabolism_Homo sapiens_hsa003800.31642711
132Caffeine metabolism_Homo sapiens_hsa002320.30891890
133Systemic lupus erythematosus_Homo sapiens_hsa053220.30444854
134T cell receptor signaling pathway_Homo sapiens_hsa046600.29965848
135Acute myeloid leukemia_Homo sapiens_hsa052210.29755457
136ABC transporters_Homo sapiens_hsa020100.29042426
137Peroxisome_Homo sapiens_hsa041460.28529902
138Metabolic pathways_Homo sapiens_hsa011000.26730673
139Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.24788132
140Sulfur metabolism_Homo sapiens_hsa009200.21157846
141Oxytocin signaling pathway_Homo sapiens_hsa049210.21153584
142Type II diabetes mellitus_Homo sapiens_hsa049300.20799014
143Vibrio cholerae infection_Homo sapiens_hsa051100.20602881
144HIF-1 signaling pathway_Homo sapiens_hsa040660.19385607
145Wnt signaling pathway_Homo sapiens_hsa043100.17445600
146Salmonella infection_Homo sapiens_hsa051320.15679347

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