SPATA33

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)9.98097772
2spermatid development (GO:0007286)9.75637144
3epithelial cilium movement (GO:0003351)9.70084644
4motile cilium assembly (GO:0044458)9.55854886
5plasma membrane fusion (GO:0045026)9.51477279
6reproduction (GO:0000003)8.73718233
7cilium movement (GO:0003341)8.15335117
8piRNA metabolic process (GO:0034587)8.11745037
9regulation of cilium movement (GO:0003352)8.06483655
10synaptonemal complex organization (GO:0070193)7.97446396
11male meiosis (GO:0007140)7.87212449
12synaptonemal complex assembly (GO:0007130)7.73296380
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.67765061
14negative regulation of inclusion body assembly (GO:0090084)7.64476190
15single fertilization (GO:0007338)6.94200202
16sperm capacitation (GO:0048240)6.78367253
17spermatogenesis (GO:0007283)6.74595757
18male gamete generation (GO:0048232)6.72138970
19organic cation transport (GO:0015695)6.31500345
20regulation of inclusion body assembly (GO:0090083)6.21988651
21gamete generation (GO:0007276)6.17326038
22fertilization (GO:0009566)6.06903276
23microtubule depolymerization (GO:0007019)5.97771101
24calcium ion-dependent exocytosis (GO:0017156)5.49604713
25germ cell development (GO:0007281)5.47627423
26behavioral response to nicotine (GO:0035095)5.38468019
27male meiosis I (GO:0007141)5.38440959
28chromosome condensation (GO:0030261)5.36953972
29spermatid nucleus differentiation (GO:0007289)5.35269163
30cellular process involved in reproduction in multicellular organism (GO:0022412)5.35182701
31DNA methylation involved in gamete generation (GO:0043046)5.32759946
32chromosome organization involved in meiosis (GO:0070192)5.26310222
33ventricular system development (GO:0021591)5.13234564
34DNA packaging (GO:0006323)5.10936913
35microtubule severing (GO:0051013)4.92112509
36cell recognition (GO:0008037)4.89166850
37multicellular organismal reproductive process (GO:0048609)4.82952021
38seminiferous tubule development (GO:0072520)4.82409385
39regulation of microtubule-based movement (GO:0060632)4.76797285
40glycerol ether metabolic process (GO:0006662)4.70843358
41meiotic nuclear division (GO:0007126)4.66305558
42ether metabolic process (GO:0018904)4.34736160
43mitochondrial respiratory chain complex I assembly (GO:0032981)4.32645294
44NADH dehydrogenase complex assembly (GO:0010257)4.32645294
45mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.32645294
46meiosis I (GO:0007127)4.31606280
47chaperone-mediated protein complex assembly (GO:0051131)4.29004225
48protein complex biogenesis (GO:0070271)4.27147876
49left/right pattern formation (GO:0060972)4.22333096
50sexual reproduction (GO:0019953)4.14156067
51response to pheromone (GO:0019236)4.11185912
52single strand break repair (GO:0000012)4.04685238
53mitochondrial respiratory chain complex assembly (GO:0033108)4.04439477
54negative regulation of transcription regulatory region DNA binding (GO:2000678)3.94966985
55respiratory chain complex IV assembly (GO:0008535)3.91201278
56multicellular organismal development (GO:0007275)3.90370390
57centriole replication (GO:0007099)3.73897573
58nonmotile primary cilium assembly (GO:0035058)3.69718831
59meiotic cell cycle (GO:0051321)3.68850571
60protein localization to cilium (GO:0061512)3.64901601
61genitalia morphogenesis (GO:0035112)3.64569452
62cytochrome complex assembly (GO:0017004)3.63042448
63protein polyglutamylation (GO:0018095)3.61283832
64sequestering of actin monomers (GO:0042989)3.55568165
65rRNA modification (GO:0000154)3.51990771
66protein refolding (GO:0042026)3.46808393
67preassembly of GPI anchor in ER membrane (GO:0016254)3.41985078
68replication fork processing (GO:0031297)3.40058866
69nucleoside diphosphate phosphorylation (GO:0006165)3.36086386
70axoneme assembly (GO:0035082)3.31518487
71regulation of spindle checkpoint (GO:0090231)3.28987305
72protein K11-linked deubiquitination (GO:0035871)3.27905765
73carnitine transport (GO:0015879)3.27083705
74amino-acid betaine transport (GO:0015838)3.27083705
75base-excision repair, AP site formation (GO:0006285)3.25808325
76negative regulation of mast cell activation (GO:0033004)3.23770852
77intraciliary transport (GO:0042073)3.21983165
78GTP biosynthetic process (GO:0006183)3.18917189
79negative regulation of telomere maintenance (GO:0032205)3.17487603
80glycolytic process (GO:0006096)3.16737026
81carnitine transmembrane transport (GO:1902603)3.16446269
82cellular ketone body metabolic process (GO:0046950)3.11458126
83microtubule polymerization or depolymerization (GO:0031109)3.10117484
84mitotic sister chromatid cohesion (GO:0007064)3.07578761
85mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.07566453
86monoubiquitinated protein deubiquitination (GO:0035520)3.06293232
87meiotic cell cycle process (GO:1903046)3.05787559
88synapsis (GO:0007129)3.04072946
89indolalkylamine metabolic process (GO:0006586)3.03855060
90mannosylation (GO:0097502)2.99838580
91nucleus organization (GO:0006997)2.99101157
92pyrimidine nucleobase catabolic process (GO:0006208)2.96340643
93cilium organization (GO:0044782)2.95515880
94DNA replication checkpoint (GO:0000076)2.91986958
95positive regulation of macrophage activation (GO:0043032)2.91656153
96microtubule-based movement (GO:0007018)2.90014954
97cellular component assembly involved in morphogenesis (GO:0010927)2.88019192
98DNA double-strand break processing (GO:0000729)2.85500680
99interferon-gamma secretion (GO:0072643)2.83392923
100UTP biosynthetic process (GO:0006228)2.83250941
101alditol metabolic process (GO:0019400)2.82439679
102ketone body metabolic process (GO:1902224)2.82091391
103polyol catabolic process (GO:0046174)2.81513889
104cilium assembly (GO:0042384)2.81163763
105cilium morphogenesis (GO:0060271)2.80391580
106protein-cofactor linkage (GO:0018065)2.79682317
107pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.77699193
108maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.75851462
109indole-containing compound catabolic process (GO:0042436)2.75001014
110indolalkylamine catabolic process (GO:0046218)2.75001014
111tryptophan catabolic process (GO:0006569)2.75001014
112regulation of nuclear cell cycle DNA replication (GO:0033262)2.74661896
113photoreceptor cell maintenance (GO:0045494)2.74615598
114negative regulation of organelle assembly (GO:1902116)2.73546373
115gene silencing by RNA (GO:0031047)2.72933006
116regulation of mitochondrial translation (GO:0070129)2.69905544
117platelet dense granule organization (GO:0060155)2.69663268
118nucleobase catabolic process (GO:0046113)2.68636746
119cornea development in camera-type eye (GO:0061303)2.68321286
120energy coupled proton transport, down electrochemical gradient (GO:0015985)2.67833253
121ATP synthesis coupled proton transport (GO:0015986)2.67833253
122regulation of telomere maintenance (GO:0032204)2.66441853
123behavioral response to ethanol (GO:0048149)2.66356428
124kynurenine metabolic process (GO:0070189)2.64627340
125lactate metabolic process (GO:0006089)2.62690304
126detection of light stimulus involved in visual perception (GO:0050908)2.62326311
127detection of light stimulus involved in sensory perception (GO:0050962)2.62326311
128rRNA methylation (GO:0031167)2.61834662
129tRNA modification (GO:0006400)2.61663788
130C-terminal protein lipidation (GO:0006501)2.61061709
131DNA deamination (GO:0045006)2.60659180
132pseudouridine synthesis (GO:0001522)2.60222979
133chaperone-mediated protein transport (GO:0072321)2.58768417
134UTP metabolic process (GO:0046051)2.57997719
135polyamine biosynthetic process (GO:0006596)2.57091366
136regulation of cilium assembly (GO:1902017)2.56507460
137recombinational repair (GO:0000725)2.56403105
138regulation of action potential (GO:0098900)2.56317915
139mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.54255108
140double-strand break repair via homologous recombination (GO:0000724)2.53520905
141peptidyl-histidine modification (GO:0018202)2.52122975
142detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.51461523
143RNA localization (GO:0006403)2.51448212
144electron transport chain (GO:0022900)2.50196328
145centriole assembly (GO:0098534)2.49776602
146cellular biogenic amine catabolic process (GO:0042402)2.49657928
147amine catabolic process (GO:0009310)2.49657928
148synaptic transmission, cholinergic (GO:0007271)2.49506786
149chromatin silencing (GO:0006342)2.49257824
150ubiquinone biosynthetic process (GO:0006744)2.49178890
151L-fucose catabolic process (GO:0042355)2.48118315
152fucose catabolic process (GO:0019317)2.48118315
153L-fucose metabolic process (GO:0042354)2.48118315
154GPI anchor metabolic process (GO:0006505)2.45744558
155tRNA processing (GO:0008033)2.45686209
156tryptophan metabolic process (GO:0006568)2.45163476
157mitochondrion degradation (GO:0000422)2.44297656
158C-terminal protein amino acid modification (GO:0018410)2.44271169
159water-soluble vitamin biosynthetic process (GO:0042364)2.42732493
160respiratory electron transport chain (GO:0022904)2.41302961
161transmission of nerve impulse (GO:0019226)2.41240040
162pyrimidine nucleotide catabolic process (GO:0006244)2.40278675
163sperm motility (GO:0030317)13.4554039
164cell wall macromolecule catabolic process (GO:0016998)12.5162421
165cell wall macromolecule metabolic process (GO:0044036)12.5162421
166fusion of sperm to egg plasma membrane (GO:0007342)12.4636677
167acrosome reaction (GO:0007340)11.8417010
168acrosome assembly (GO:0001675)11.7800471
169sperm-egg recognition (GO:0035036)11.2460063
170binding of sperm to zona pellucida (GO:0007339)10.3907544
171multicellular organism reproduction (GO:0032504)10.0502170
172cell-cell recognition (GO:0009988)10.0423754
173axonemal dynein complex assembly (GO:0070286)10.0188812

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.67131242
2EZH2_22144423_ChIP-Seq_EOC_Human4.80231799
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.98515722
4HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.99302459
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.90051876
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.82321563
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.74975998
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.71096614
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.65606212
10VDR_22108803_ChIP-Seq_LS180_Human2.42828380
11STAT6_21828071_ChIP-Seq_BEAS2B_Human2.38980256
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.33998974
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.31353030
14ZNF274_21170338_ChIP-Seq_K562_Hela2.23959678
15CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.22439040
16IGF1R_20145208_ChIP-Seq_DFB_Human2.22000498
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.21228507
18EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.09187982
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.04530109
20CTBP1_25329375_ChIP-Seq_LNCAP_Human2.02151762
21GBX2_23144817_ChIP-Seq_PC3_Human1.98650542
22FUS_26573619_Chip-Seq_HEK293_Human1.97377943
23IRF1_19129219_ChIP-ChIP_H3396_Human1.90676606
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.88726612
25ETS1_20019798_ChIP-Seq_JURKAT_Human1.87331064
26ELK4_26923725_Chip-Seq_MESODERM_Mouse1.85127123
27EWS_26573619_Chip-Seq_HEK293_Human1.84636809
28JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.82687192
29KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.78646236
30MYC_18940864_ChIP-ChIP_HL60_Human1.78605504
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.75439279
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75056585
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.71415525
34PCGF2_27294783_Chip-Seq_ESCs_Mouse1.71058380
35FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.68715146
36TP53_22573176_ChIP-Seq_HFKS_Human1.67271451
37TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.66515778
38SOX2_22085726_ChIP-Seq_NPCs_Mouse1.64010066
39STAT1_17558387_ChIP-Seq_HELA_Human1.63487659
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.61349578
41P300_19829295_ChIP-Seq_ESCs_Human1.60294490
42MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.59934692
43NOTCH1_21737748_ChIP-Seq_TLL_Human1.57635510
44VDR_23849224_ChIP-Seq_CD4+_Human1.57509446
45ER_23166858_ChIP-Seq_MCF-7_Human1.57480275
46GATA3_21867929_ChIP-Seq_CD8_Mouse1.56664692
47GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.51716266
48ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.48766190
49MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44995795
50WDR5_24793694_ChIP-Seq_LNCAP_Human1.44891401
51RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.44609816
52NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.41049801
53SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.39731246
54CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.39615203
55FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.37962234
56TAL1_26923725_Chip-Seq_HPCs_Mouse1.37767969
57KDM2B_26808549_Chip-Seq_REH_Human1.36728406
58PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.35821929
59CBP_20019798_ChIP-Seq_JUKART_Human1.35370614
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35370614
61REST_21632747_ChIP-Seq_MESCs_Mouse1.35278340
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.35245028
63CBX2_27304074_Chip-Seq_ESCs_Mouse1.34629096
64ELK1_19687146_ChIP-ChIP_HELA_Human1.34055295
65P53_21459846_ChIP-Seq_SAOS-2_Human1.33268642
66NCOR_22424771_ChIP-Seq_293T_Human1.32770406
67LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.32521544
68SALL1_21062744_ChIP-ChIP_HESCs_Human1.31558920
69GATA3_21878914_ChIP-Seq_MCF-7_Human1.29276015
70KAP1_22055183_ChIP-Seq_ESCs_Mouse1.28524319
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.26444957
72SRF_21415370_ChIP-Seq_HL-1_Mouse1.26007541
73ERA_21632823_ChIP-Seq_H3396_Human1.25599358
74ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.24638858
75NFE2_27457419_Chip-Seq_LIVER_Mouse1.22147200
76RAD21_21589869_ChIP-Seq_MESCs_Mouse1.21893355
77GABP_19822575_ChIP-Seq_HepG2_Human1.21888195
78GF1_26923725_Chip-Seq_HPCs_Mouse1.21841366
79FLI1_21867929_ChIP-Seq_TH2_Mouse1.21484159
80FOXA1_27270436_Chip-Seq_PROSTATE_Human1.21292119
81FOXA1_25329375_ChIP-Seq_VCAP_Human1.21292119
82AR_25329375_ChIP-Seq_VCAP_Human1.21119875
83PCGF2_27294783_Chip-Seq_NPCs_Mouse1.20813014
84GATA3_21867929_ChIP-Seq_TH1_Mouse1.20270295
85TP63_19390658_ChIP-ChIP_HaCaT_Human1.20251312
86HOXB7_26014856_ChIP-Seq_BT474_Human1.19814088
87CTBP2_25329375_ChIP-Seq_LNCAP_Human1.19771628
88MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.18872616
89KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18759835
90ETV2_25802403_ChIP-Seq_MESCs_Mouse1.18504316
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18463776
92FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.17507367
93CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17236077
94STAT3_23295773_ChIP-Seq_U87_Human1.17039189
95RBPJ_22232070_ChIP-Seq_NCS_Mouse1.16757240
96SOX2_19829295_ChIP-Seq_ESCs_Human1.16632700
97NANOG_19829295_ChIP-Seq_ESCs_Human1.16632700
98TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.15820577
99UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14294934
100SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.13251003
101PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13188987
102FOXP3_21729870_ChIP-Seq_TREG_Human1.13125717
103GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.12516595
104BCAT_22108803_ChIP-Seq_LS180_Human1.12474140
105TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12146138
106TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12087664
107POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12087664
108SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11580148
109SPI1_26923725_Chip-Seq_HPCs_Mouse1.11151656
110SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10768118
111MYC_19829295_ChIP-Seq_ESCs_Human1.10714113
112TCF4_23295773_ChIP-Seq_U87_Human1.10672183
113NANOG_20526341_ChIP-Seq_ESCs_Human1.09690515
114ERG_20517297_ChIP-Seq_VCAP_Human1.09123574
115PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.09016283
116E2F4_17652178_ChIP-ChIP_JURKAT_Human1.08481319
117NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07827625
118RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.07338643
119PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.07319798
120CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07207206
121TET1_21451524_ChIP-Seq_MESCs_Mouse1.07040317
122MYC_27129775_Chip-Seq_CORNEA_Mouse1.06677158
123YY1_22570637_ChIP-Seq_MALME-3M_Human1.06530702
124RXRA_24833708_ChIP-Seq_LIVER_Mouse1.06034241
125SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.05875092
126REST_18959480_ChIP-ChIP_MESCs_Mouse1.05755658
127ESET_19884257_ChIP-Seq_ESCs_Mouse1.05048673
128RUNX1_26923725_Chip-Seq_HPCs_Mouse1.04681923
129TCF4_22108803_ChIP-Seq_LS180_Human1.03961341
130AR_20517297_ChIP-Seq_VCAP_Human1.03292256
131EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03254574
132TAF2_19829295_ChIP-Seq_ESCs_Human1.02067376
133CRX_20693478_ChIP-Seq_RETINA_Mouse1.02051976
134OCT4_20526341_ChIP-Seq_ESCs_Human1.01898309
135NANOG_18555785_Chip-Seq_ESCs_Mouse1.01267751
136CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.99856010
137RARA_24833708_ChIP-Seq_LIVER_Mouse0.99023950
138GATA1_19941827_ChIP-Seq_MEL86_Mouse0.98747708
139LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98101949
140FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98046743
141EZH2_27304074_Chip-Seq_ESCs_Mouse0.96995146
142EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.96823562
143PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.96589283
144ESR1_15608294_ChIP-ChIP_MCF-7_Human0.96492701
145EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.96326218
146TDRD3_21172665_ChIP-Seq_MCF-7_Human0.95463594
147CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.95299117
148SMAD4_21799915_ChIP-Seq_A2780_Human0.94965882
149OCT4_18555785_Chip-Seq_ESCs_Mouse0.94567009
150SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94156238
151KDM5A_27292631_Chip-Seq_BREAST_Human0.93599730
152RNF2_27304074_Chip-Seq_NSC_Mouse0.93433781
153NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.92880678
154P53_22387025_ChIP-Seq_ESCs_Mouse0.92418000
155PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92309330
156MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92244639
157JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.92003721
158TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91284034
159CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.90465359
160EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.89893239
161RUNX2_22187159_ChIP-Seq_PCA_Human0.89730898
162NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89276053
163FLI1_21867929_ChIP-Seq_CD8_Mouse0.89087004
164TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.88853719
165RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.88547086
166SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88205044
167RAC3_21632823_ChIP-Seq_H3396_Human0.87986419
168TAF15_26573619_Chip-Seq_HEK293_Human0.87977858
169CTCF_20526341_ChIP-Seq_ESCs_Human0.87936782
170GF1B_26923725_Chip-Seq_HPCs_Mouse0.87315904
171NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.86972631
172SOX11_22085726_ChIP-Seq_ESNs_Mouse0.86970698
173NFYB_21822215_ChIP-Seq_K562_Human0.86497256
174SOX9_26525672_Chip-Seq_HEART_Mouse0.86388651

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.99697661
2MP0001929_abnormal_gametogenesis5.59023895
3MP0008877_abnormal_DNA_methylation4.57924662
4MP0002210_abnormal_sex_determination3.51959846
5MP0002161_abnormal_fertility/fecundity3.23815619
6MP0001145_abnormal_male_reproductive2.96471860
7MP0006292_abnormal_olfactory_placode2.83871628
8MP0005670_abnormal_white_adipose2.66057933
9MP0000653_abnormal_sex_gland2.55542125
10MP0002653_abnormal_ependyma_morphology2.28180553
11MP0003880_abnormal_central_pattern2.18220289
12MP0005646_abnormal_pituitary_gland2.14716273
13MP0003787_abnormal_imprinting2.13582067
14MP0008872_abnormal_physiological_respon2.06852211
15MP0005410_abnormal_fertilization15.9456886
16MP0003646_muscle_fatigue1.92438305
17MP0002160_abnormal_reproductive_system1.85731201
18MP0002938_white_spotting1.78803372
19MP0004147_increased_porphyrin_level1.76198254
20MP0000372_irregular_coat_pigmentation1.72004808
21MP0008789_abnormal_olfactory_epithelium1.71658296
22MP0001529_abnormal_vocalization1.63476473
23MP0004885_abnormal_endolymph1.62779001
24MP0003718_maternal_effect1.61911023
25MP0008875_abnormal_xenobiotic_pharmacok1.60791846
26MP0006276_abnormal_autonomic_nervous1.58637618
27MP0004233_abnormal_muscle_weight1.55996257
28MP0003121_genomic_imprinting1.54338228
29MP0005645_abnormal_hypothalamus_physiol1.54012484
30MP0000631_abnormal_neuroendocrine_gland1.52734069
31MP0010386_abnormal_urinary_bladder1.50333586
32MP0005623_abnormal_meninges_morphology1.50138451
33MP0009745_abnormal_behavioral_response1.47960396
34MP0003195_calcinosis1.43826592
35MP0001485_abnormal_pinna_reflex1.40921357
36MP0002272_abnormal_nervous_system1.39420601
37MP0000427_abnormal_hair_cycle1.33186116
38MP0005394_taste/olfaction_phenotype1.31743727
39MP0005499_abnormal_olfactory_system1.31743727
40MP0002234_abnormal_pharynx_morphology1.31558327
41MP0002163_abnormal_gland_morphology1.29091041
42MP0001986_abnormal_taste_sensitivity1.27025140
43MP0000049_abnormal_middle_ear1.26384445
44MP0004142_abnormal_muscle_tone1.25901037
45MP0001984_abnormal_olfaction1.25418866
46MP0002638_abnormal_pupillary_reflex1.22567269
47MP0000778_abnormal_nervous_system1.21865839
48MP0001486_abnormal_startle_reflex1.21337543
49MP0002735_abnormal_chemical_nociception1.20060205
50MP0002557_abnormal_social/conspecific_i1.20050901
51MP0003122_maternal_imprinting1.18867583
52MP0002734_abnormal_mechanical_nocicepti1.12576337
53MP0004742_abnormal_vestibular_system1.10959773
54MP0002733_abnormal_thermal_nociception1.09320978
55MP0002876_abnormal_thyroid_physiology1.08493627
56MP0003136_yellow_coat_color1.08052175
57MP0003693_abnormal_embryo_hatching1.07908020
58MP0005379_endocrine/exocrine_gland_phen1.07636654
59MP0001970_abnormal_pain_threshold1.06707277
60MP0002282_abnormal_trachea_morphology1.03775897
61MP0001765_abnormal_ion_homeostasis1.00187449
62MP0000026_abnormal_inner_ear0.99796292
63MP0001905_abnormal_dopamine_level0.98910944
64MP0003119_abnormal_digestive_system0.98477810
65MP0002184_abnormal_innervation0.97186238
66MP0005195_abnormal_posterior_eye0.96296935
67MP0009046_muscle_twitch0.95839286
68MP0002752_abnormal_somatic_nervous0.95690626
69MP0003635_abnormal_synaptic_transmissio0.95308516
70MP0002064_seizures0.94957655
71MP0001919_abnormal_reproductive_system0.94142751
72MP0004036_abnormal_muscle_relaxation0.93800181
73MP0003123_paternal_imprinting0.93197346
74MP0005174_abnormal_tail_pigmentation0.93032890
75MP0005389_reproductive_system_phenotype0.92022419
76MP0008058_abnormal_DNA_repair0.91695911
77MP0002067_abnormal_sensory_capabilities0.89371591
78MP0005084_abnormal_gallbladder_morpholo0.87515611
79MP0001963_abnormal_hearing_physiology0.87204199
80MP0002063_abnormal_learning/memory/cond0.86808169
81MP0005423_abnormal_somatic_nervous0.83544100
82MP0004924_abnormal_behavior0.81169045
83MP0005386_behavior/neurological_phenoty0.81169045
84MP0003937_abnormal_limbs/digits/tail_de0.80844105
85MP0005647_abnormal_sex_gland0.78727601
86MP0003011_delayed_dark_adaptation0.78241752
87MP0008995_early_reproductive_senescence0.76227087
88MP0002269_muscular_atrophy0.68063707
89MP0004084_abnormal_cardiac_muscle0.66694673
90MP0000751_myopathy0.66464473
91MP0006036_abnormal_mitochondrial_physio0.66267409
92MP0003115_abnormal_respiratory_system0.65031316
93MP0002837_dystrophic_cardiac_calcinosis0.64315531
94MP0003329_amyloid_beta_deposits0.57427838
95MP0003878_abnormal_ear_physiology0.56520581
96MP0005377_hearing/vestibular/ear_phenot0.56520581
97MP0005636_abnormal_mineral_homeostasis0.55152279
98MP0002736_abnormal_nociception_after0.54841611
99MP0008057_abnormal_DNA_replication0.54645254
100MP0005666_abnormal_adipose_tissue0.53588029
101MP0000358_abnormal_cell_content/0.51674987
102MP0010094_abnormal_chromosome_stability0.48938889
103MP0000749_muscle_degeneration0.47198487
104MP0003950_abnormal_plasma_membrane0.47148735
105MP0005253_abnormal_eye_physiology0.46489703
106MP0004145_abnormal_muscle_electrophysio0.44745559
107MP0003699_abnormal_female_reproductive0.43941900
108MP0002928_abnormal_bile_duct0.41987022
109MP0004133_heterotaxia0.41653330
110MP0005551_abnormal_eye_electrophysiolog0.39598010
111MP0001293_anophthalmia0.37742550
112MP0002102_abnormal_ear_morphology0.37129674
113MP0004270_analgesia0.36698520
114MP0004087_abnormal_muscle_fiber0.36310316
115MP0001324_abnormal_eye_pigmentation0.36257083
116MP0006035_abnormal_mitochondrial_morpho0.36241068
117MP0001764_abnormal_homeostasis0.36070228
118MP0005397_hematopoietic_system_phenotyp0.35403426
119MP0001545_abnormal_hematopoietic_system0.35403426
120MP0003786_premature_aging0.35074177
121MP0000534_abnormal_ureter_morphology0.34293790
122MP0004811_abnormal_neuron_physiology0.33939487
123MP0009278_abnormal_bone_marrow0.32346738
124MP0005391_vision/eye_phenotype0.32220964
125MP0001968_abnormal_touch/_nociception0.31683625
126MP0002106_abnormal_muscle_physiology0.30297628
127MP0003861_abnormal_nervous_system0.29848848
128MP0010630_abnormal_cardiac_muscle0.29446529
129MP0001730_embryonic_growth_arrest0.29082733
130MP0000569_abnormal_digit_pigmentation0.28673510
131MP0008007_abnormal_cellular_replicative0.28507029
132MP0003942_abnormal_urinary_system0.28200283
133MP0004043_abnormal_pH_regulation0.27927624
134MP0006072_abnormal_retinal_apoptosis0.27867384
135MP0001119_abnormal_female_reproductive0.27722589
136MP0002152_abnormal_brain_morphology0.27250275
137MP0003633_abnormal_nervous_system0.26553111
138MP0002132_abnormal_respiratory_system0.26446883
139MP0003948_abnormal_gas_homeostasis0.25694110
140MP0003879_abnormal_hair_cell0.25240673
141MP0009115_abnormal_fat_cell0.24900989
142MP0002169_no_abnormal_phenotype0.23220348
143MP0002295_abnormal_pulmonary_circulatio0.23138113
144MP0002873_normal_phenotype0.22998417
145MP0001727_abnormal_embryo_implantation0.22469939
146MP0002971_abnormal_brown_adipose0.21783630
147MP0003631_nervous_system_phenotype0.21598175
148MP0004215_abnormal_myocardial_fiber0.21485171
149MP0004085_abnormal_heartbeat0.20647664
150MP0005620_abnormal_muscle_contractility0.19424139
151MP0004808_abnormal_hematopoietic_stem0.19050161
152MP0008961_abnormal_basal_metabolism0.19019779
153MP0006138_congestive_heart_failure0.18989633
154MP0000759_abnormal_skeletal_muscle0.18949187
155MP0005369_muscle_phenotype0.18446429
156MP0000604_amyloidosis0.18423161
157MP0003111_abnormal_nucleus_morphology0.17468257
158MP0009250_abnormal_appendicular_skeleto0.17208722
159MP0002108_abnormal_muscle_morphology0.16958153
160MP0001440_abnormal_grooming_behavior0.16629314
161MP0004130_abnormal_muscle_cell0.16608484
162MP0002572_abnormal_emotion/affect_behav0.16382153

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.64670511
2Abnormal respiratory epithelium morphology (HP:0012253)9.19369864
3Abnormal respiratory motile cilium morphology (HP:0005938)9.19369864
4Rhinitis (HP:0012384)7.94529487
5Abnormal ciliary motility (HP:0012262)7.69576461
6Chronic bronchitis (HP:0004469)7.48892843
7Infertility (HP:0000789)6.78754186
8Nasal polyposis (HP:0100582)6.24427656
9Abnormality of the nasal mucosa (HP:0000433)5.12892547
10Bronchiectasis (HP:0002110)4.52134523
11Bronchitis (HP:0012387)4.34980667
12Nephronophthisis (HP:0000090)4.26567289
13Male infertility (HP:0003251)4.12092972
14Pancreatic cysts (HP:0001737)3.85295629
15Abnormal spermatogenesis (HP:0008669)3.34538975
16Acute necrotizing encephalopathy (HP:0006965)3.30268588
17Mitochondrial inheritance (HP:0001427)3.29073118
18Abnormality of the renal medulla (HP:0100957)3.18943344
19Hepatocellular necrosis (HP:0001404)3.15699573
20Recurrent otitis media (HP:0000403)3.11610603
21Increased CSF lactate (HP:0002490)3.07899048
22Recurrent sinusitis (HP:0011108)3.06215343
23Abnormal mitochondria in muscle tissue (HP:0008316)2.98336070
24Type II lissencephaly (HP:0007260)2.91387378
25Acute encephalopathy (HP:0006846)2.84933446
26Hepatic necrosis (HP:0002605)2.81922982
27Medial flaring of the eyebrow (HP:0010747)2.78493293
28Congenital stationary night blindness (HP:0007642)2.77957927
29Abnormality of midbrain morphology (HP:0002418)2.77374956
30Molar tooth sign on MRI (HP:0002419)2.77374956
31Tubulointerstitial nephritis (HP:0001970)2.76396640
32Progressive macrocephaly (HP:0004481)2.73637574
33Tubular atrophy (HP:0000092)2.63121029
34Sclerocornea (HP:0000647)2.48133320
35Tubulointerstitial abnormality (HP:0001969)2.47957006
36Gonadotropin excess (HP:0000837)2.47311740
37Attenuation of retinal blood vessels (HP:0007843)2.46203183
38Abnormality of the lower motor neuron (HP:0002366)2.44585246
39Abnormal rod and cone electroretinograms (HP:0008323)2.38779469
40Azoospermia (HP:0000027)2.36734217
41Chronic hepatic failure (HP:0100626)2.33849528
42Pendular nystagmus (HP:0012043)2.29353450
43Protruding tongue (HP:0010808)2.27178120
44Abnormality of DNA repair (HP:0003254)2.25921965
45Recurrent bronchitis (HP:0002837)2.25705884
46Impulsivity (HP:0100710)2.24756914
47Abnormal number of erythroid precursors (HP:0012131)2.24433407
48Lipid accumulation in hepatocytes (HP:0006561)2.24201428
49Short middle phalanx of the 5th finger (HP:0004220)2.18627829
50Abnormality of the renal collecting system (HP:0004742)2.14782364
51Anencephaly (HP:0002323)2.13756263
52Lissencephaly (HP:0001339)2.13541582
53Increased hepatocellular lipid droplets (HP:0006565)2.12350955
54Aganglionic megacolon (HP:0002251)2.10365130
55Cerebral edema (HP:0002181)2.09486333
56Tubulointerstitial fibrosis (HP:0005576)2.08964244
57Hypoplastic iliac wings (HP:0002866)2.08206964
58Aplasia/Hypoplasia of the uvula (HP:0010293)2.08120702
59Retinal dysplasia (HP:0007973)2.07387532
60Absent rod-and cone-mediated responses on ERG (HP:0007688)2.04767107
61Abnormal gallbladder physiology (HP:0012438)2.02471068
62Cholecystitis (HP:0001082)2.02471068
63Patellar aplasia (HP:0006443)2.02263805
64Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.1848864
65Absent/shortened dynein arms (HP:0200106)12.8685605
66Dynein arm defect of respiratory motile cilia (HP:0012255)12.8685605
67Abnormality of the labia minora (HP:0012880)1.99198910
68Brushfield spots (HP:0001088)1.98957548
69Aplasia/Hypoplasia of the patella (HP:0006498)1.98550688
70Increased serum lactate (HP:0002151)1.98138707
71Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.97349653
72Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.96963047
73Abnormality of alanine metabolism (HP:0010916)1.96963047
74Hyperalaninemia (HP:0003348)1.96963047
75Absent thumb (HP:0009777)1.96913766
76Bony spicule pigmentary retinopathy (HP:0007737)1.96429276
77Abnormality of cells of the erythroid lineage (HP:0012130)1.95900159
78Aplasia/Hypoplasia of the spleen (HP:0010451)1.95641037
79Abnormality of dental color (HP:0011073)1.93946326
80Amyotrophic lateral sclerosis (HP:0007354)1.93399317
81Abnormality of the phalanges of the 5th finger (HP:0004213)1.93100545
82Occipital encephalocele (HP:0002085)1.92616816
83Postaxial foot polydactyly (HP:0001830)1.92516331
84Stage 5 chronic kidney disease (HP:0003774)1.92486293
85Optic disc pallor (HP:0000543)1.90998487
86Abnormality of the ileum (HP:0001549)1.89977114
87Preaxial hand polydactyly (HP:0001177)1.89284815
88Fibular hypoplasia (HP:0003038)1.87609123
89Abnormal drinking behavior (HP:0030082)1.87187576
90Polydipsia (HP:0001959)1.87187576
91Exercise-induced myalgia (HP:0003738)1.86984549
92Duplicated collecting system (HP:0000081)1.85521802
93Abnormal protein glycosylation (HP:0012346)1.84953184
94Abnormal glycosylation (HP:0012345)1.84953184
95Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.84953184
96Abnormal protein N-linked glycosylation (HP:0012347)1.84953184
97Small intestinal stenosis (HP:0012848)1.84755579
98Duodenal stenosis (HP:0100867)1.84755579
99Congenital hepatic fibrosis (HP:0002612)1.83982708
100Anophthalmia (HP:0000528)1.83622535
101Meckel diverticulum (HP:0002245)1.81160045
102Renal Fanconi syndrome (HP:0001994)1.80597584
103Polyuria (HP:0000103)1.80011214
104Ectopic kidney (HP:0000086)1.78442995
105Respiratory failure (HP:0002878)1.78151244
106Chromosomal breakage induced by crosslinking agents (HP:0003221)1.77996652
107Lactic acidosis (HP:0003128)1.77415466
108Congenital malformation of the right heart (HP:0011723)1.77112099
109Double outlet right ventricle (HP:0001719)1.77112099
110Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.75012892
111Dyschromatopsia (HP:0007641)1.74821013
112Renal cortical cysts (HP:0000803)1.73715669
113Hyperventilation (HP:0002883)1.72643711
114Hypoplasia of the capital femoral epiphysis (HP:0003090)1.71498725
115Abnormality of the renal cortex (HP:0011035)1.69785798
116Oculomotor apraxia (HP:0000657)1.69316346
117Abnormality of dentin (HP:0010299)1.60224537
118Congenital primary aphakia (HP:0007707)1.59399783
119Aplasia/Hypoplasia of the lens (HP:0008063)1.59379797
120Abnormality of renal excretion (HP:0011036)1.59331682
121Bundle branch block (HP:0011710)1.59240135
122Gait imbalance (HP:0002141)1.59223066
123Postaxial hand polydactyly (HP:0001162)1.58995736
124Choroideremia (HP:0001139)1.57098324
125Renal dysplasia (HP:0000110)1.56491109
126Abnormality of the dental root (HP:0006486)1.56479941
127Taurodontia (HP:0000679)1.56479941
128Abnormality of permanent molar morphology (HP:0011071)1.56479941
129Chronic sinusitis (HP:0011109)1.56111279
130Facial cleft (HP:0002006)1.55366585
131Asymmetric septal hypertrophy (HP:0001670)1.55123959
132Impaired proprioception (HP:0010831)1.54968824
133Decreased central vision (HP:0007663)1.53341381
134Bile duct proliferation (HP:0001408)1.51799807
135Abnormal biliary tract physiology (HP:0012439)1.51799807
136Myoglobinuria (HP:0002913)1.49996899
137Short ribs (HP:0000773)1.49505366
138Spastic tetraparesis (HP:0001285)1.47464356
139Bell-shaped thorax (HP:0001591)1.47216443
140Cystic liver disease (HP:0006706)1.46868764
141Exercise-induced muscle cramps (HP:0003710)1.46552216
142Pancreatic fibrosis (HP:0100732)1.46414525
143Abnormality of molar (HP:0011077)1.44746382
144Abnormality of molar morphology (HP:0011070)1.44746382
145Abnormality of the dental pulp (HP:0006479)1.44717906
146Nephrogenic diabetes insipidus (HP:0009806)1.36314238
147Abnormal urine output (HP:0012590)1.34430393
148Cerebellar dysplasia (HP:0007033)1.34004825
149Easy fatigability (HP:0003388)1.33099480
150True hermaphroditism (HP:0010459)1.32118780
151Absent epiphyses (HP:0010577)1.32100899
152Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.32100899
153Decreased electroretinogram (ERG) amplitude (HP:0000654)1.31418448
154Rhabdomyolysis (HP:0003201)1.29973557
155Neurofibrillary tangles (HP:0002185)1.29093272
156Upper motor neuron abnormality (HP:0002127)1.27254247
157Heterotopia (HP:0002282)1.26957180
158Poor coordination (HP:0002370)1.25610716
159Supernumerary spleens (HP:0009799)1.25070371
160Vaginal atresia (HP:0000148)1.24530134
161Short thorax (HP:0010306)1.23627599
162Deformed sella turcica (HP:0002681)1.23469657
163Abnormality of ocular smooth pursuit (HP:0000617)1.23430330
164Aplasia/Hypoplasia of the tongue (HP:0010295)1.23030255
165Genital tract atresia (HP:0001827)1.22769759
166Median cleft lip (HP:0000161)1.22174111
167Hemorrhage of the eye (HP:0011885)1.21789550
168Nephropathy (HP:0000112)1.21712591

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.63659404
2PDK48.63659404
3TESK15.85054967
4PDK25.56483699
5FRK4.67404235
6PRKD34.16714207
7ICK4.01081148
8MAP4K23.68591719
9NUAK13.15142296
10ADRBK22.75028481
11BCKDK2.65317273
12CASK2.44919178
13PTK2B2.44723719
14WNK42.23718634
15VRK22.23126103
16STK392.10388031
17INSRR2.10061683
18GRK12.07591591
19TLK12.06258533
20BMPR1B2.02412012
21STK161.90343086
22DYRK21.89051781
23ZAK1.87112529
24MAPK131.75790217
25STK381.75206541
26PNCK1.74634478
27NEK21.59893901
28OXSR11.41468962
29DYRK1B1.37515378
30SIK21.36324063
31MAPK151.30209890
32NME11.29866109
33VRK11.19659652
34CDK81.19550931
35PDK11.14824320
36MKNK21.10652285
37PAK31.08676166
38CAMKK20.99269838
39TAF10.97052285
40TAOK30.96221392
41CSNK1G20.95556672
42TNIK0.94946263
43EPHA40.91968909
44CCNB10.90643544
45CSNK1G30.89892754
46PINK10.88306411
47ACVR1B0.87989129
48BUB10.87363832
49PLK20.86293258
50CSNK1A1L0.85659191
51IRAK10.83355733
52PRKCI0.83026691
53ADRBK10.81534199
54WNK10.81037712
55DYRK30.80788075
56TYRO30.79964047
57LMTK20.79796960
58TRIM280.75227758
59CSNK1G10.74166178
60PLK30.68887086
61PRKCE0.68661447
62PDPK10.68387435
63STK38L0.65928713
64PASK0.65794320
65STK30.63853933
66MUSK0.62942078
67FGFR20.61962712
68TTK0.57078600
69BCR0.55389912
70CDK190.53412304
71EPHA30.52152908
72CAMK10.51845098
73CHEK20.50696570
74EEF2K0.49790236
75NTRK20.49751197
76MKNK10.47637816
77RIPK40.47587891
78SRPK10.47395989
79RPS6KA50.44722813
80DAPK20.44637534
81CSNK1A10.43919470
82TESK20.42557711
83NTRK30.41981780
84MAP2K20.41697823
85PRKCG0.41506831
86AURKB0.40185960
87LIMK10.40136130
88MST40.39135128
89AKT30.39015212
90CHEK10.36844925
91IRAK20.34272237
92ERBB30.33857907
93DYRK1A0.33305281
94CSNK1E0.32677809
95PAK10.31843542
96CDC70.30775738
97TNK20.30272355
98PLK40.29406210
99CHUK0.29231934
100MAP2K60.28762923
101CAMK1G0.27799337
102WEE10.27526891
103CAMKK10.26812583
104ATR0.24133345
105ATM0.23783447
106BRSK20.23349310
107PAK20.21660089
108MAPKAPK50.20193843
109BRAF0.19501524
110PRKAA10.19282343
111PRKCZ0.18153123
112MTOR0.17413919
113MAP3K100.15733724
114CDK150.14665589
115WNK30.14575253
116PAK40.14165552
117MAP3K40.13990815
118RPS6KB10.13899405
119BRSK10.13476967
120CDK180.13340507
121PLK10.12472986
122OBSCN0.12228863
123TTN0.11893506
124PRKCQ0.11854486
125MARK20.10894857
126CDK11A0.10565239
127MYLK0.10201181
128CDK140.09039548
129PRKG20.07698267
130RPS6KA10.07589884
131CAMK2A0.07473072
132MARK30.07398822
133CSNK2A10.06986591
134PRKACG0.05747291
135NEK60.05733903
136PRKG10.04351531
137GSK3B0.03714064
138PHKG20.03623295
139PHKG10.03623295
140MAPK80.03456024
141PAK60.02535444
142PRKACB0.02092433
143PRKCD0.01922585
144PRKCA0.01784542
145PRKCB0.01140252
146STK110.01023697
147AURKA0.00779145
148CDK10.00774612
149PRKACA0.00711755
150MAPK10-0.0381805
151TRIB3-0.0375776
152CSF1R-0.0348425
153MAP3K5-0.0175370
154RPS6KA3-0.0140758
155CSNK2A2-0.0136070
156MAP2K7-0.0128510
157MARK1-0.0119172
158CDK2-0.0109415
159PKN1-0.0070046
160MINK1-0.0001655

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.41384207
2Fatty acid biosynthesis_Homo sapiens_hsa000614.10143583
3Pyruvate metabolism_Homo sapiens_hsa006203.88613368
4Vitamin B6 metabolism_Homo sapiens_hsa007503.64555592
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.18987866
6Propanoate metabolism_Homo sapiens_hsa006403.15041648
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.97001370
8Linoleic acid metabolism_Homo sapiens_hsa005912.88753016
9Glucagon signaling pathway_Homo sapiens_hsa049222.77140479
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.52282879
11Basal transcription factors_Homo sapiens_hsa030222.44922772
12Homologous recombination_Homo sapiens_hsa034402.43437099
13RNA polymerase_Homo sapiens_hsa030202.39785058
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.38724635
15Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.26596305
16Protein export_Homo sapiens_hsa030602.12743455
17Phototransduction_Homo sapiens_hsa047442.06093240
18Selenocompound metabolism_Homo sapiens_hsa004502.05913176
19Cardiac muscle contraction_Homo sapiens_hsa042602.05515871
20Butanoate metabolism_Homo sapiens_hsa006501.99927445
21Carbohydrate digestion and absorption_Homo sapiens_hsa049731.95722768
22Nicotine addiction_Homo sapiens_hsa050331.94525576
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.84995885
24Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.82842333
25Pentose phosphate pathway_Homo sapiens_hsa000301.81784998
26Huntingtons disease_Homo sapiens_hsa050161.81083430
27Glycerolipid metabolism_Homo sapiens_hsa005611.77487402
28Amphetamine addiction_Homo sapiens_hsa050311.73090245
29Ribosome_Homo sapiens_hsa030101.72627143
30PPAR signaling pathway_Homo sapiens_hsa033201.66309084
31Carbon metabolism_Homo sapiens_hsa012001.66059286
32Oocyte meiosis_Homo sapiens_hsa041141.64485187
33Fructose and mannose metabolism_Homo sapiens_hsa000511.62334075
34Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.61905672
35One carbon pool by folate_Homo sapiens_hsa006701.58816012
36Glycerophospholipid metabolism_Homo sapiens_hsa005641.57551284
37Maturity onset diabetes of the young_Homo sapiens_hsa049501.57439103
38Sulfur relay system_Homo sapiens_hsa041221.51409451
39Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.50803205
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47983179
41Fatty acid metabolism_Homo sapiens_hsa012121.45791534
42RNA degradation_Homo sapiens_hsa030181.45590591
43Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.43934389
44DNA replication_Homo sapiens_hsa030301.43335211
45Nucleotide excision repair_Homo sapiens_hsa034201.43031651
46Fat digestion and absorption_Homo sapiens_hsa049751.42003250
47Fatty acid degradation_Homo sapiens_hsa000711.41718118
48Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.39682923
49Dorso-ventral axis formation_Homo sapiens_hsa043201.38881482
50Nitrogen metabolism_Homo sapiens_hsa009101.38484617
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.38236314
52Base excision repair_Homo sapiens_hsa034101.36959757
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36195320
54Fanconi anemia pathway_Homo sapiens_hsa034601.36160249
55Ether lipid metabolism_Homo sapiens_hsa005651.31443409
56Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.30046412
57Tryptophan metabolism_Homo sapiens_hsa003801.28856164
58Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.26640647
59Cysteine and methionine metabolism_Homo sapiens_hsa002701.25794002
60Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.25192718
61Renin secretion_Homo sapiens_hsa049241.23951579
62Mineral absorption_Homo sapiens_hsa049781.22730722
63Proteasome_Homo sapiens_hsa030501.18345467
64Peroxisome_Homo sapiens_hsa041461.18229426
65Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.17816350
66Steroid biosynthesis_Homo sapiens_hsa001001.14826791
67Mismatch repair_Homo sapiens_hsa034301.12522577
68Glycosaminoglycan degradation_Homo sapiens_hsa005311.11881638
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.10883907
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.07313704
71Purine metabolism_Homo sapiens_hsa002301.04921886
72Caffeine metabolism_Homo sapiens_hsa002321.03926152
73Regulation of autophagy_Homo sapiens_hsa041401.02595676
74Collecting duct acid secretion_Homo sapiens_hsa049661.01709110
75Non-homologous end-joining_Homo sapiens_hsa034501.01373879
76Glutathione metabolism_Homo sapiens_hsa004800.98541875
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.97729206
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.96142519
79Biosynthesis of amino acids_Homo sapiens_hsa012300.95454885
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.93075031
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.92912515
82Long-term potentiation_Homo sapiens_hsa047200.92568709
83Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.87668213
84Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.87057216
85Morphine addiction_Homo sapiens_hsa050320.85897841
86Hedgehog signaling pathway_Homo sapiens_hsa043400.84592347
87Spliceosome_Homo sapiens_hsa030400.84578229
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.84563984
89beta-Alanine metabolism_Homo sapiens_hsa004100.82985244
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.82744514
91Insulin secretion_Homo sapiens_hsa049110.82473706
92mRNA surveillance pathway_Homo sapiens_hsa030150.81201490
93cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80590902
94Arachidonic acid metabolism_Homo sapiens_hsa005900.79594596
95Antigen processing and presentation_Homo sapiens_hsa046120.79072310
96Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.76473446
97Retinol metabolism_Homo sapiens_hsa008300.76157888
98Folate biosynthesis_Homo sapiens_hsa007900.73695069
99Estrogen signaling pathway_Homo sapiens_hsa049150.73251696
100Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.73105278
101Chemical carcinogenesis_Homo sapiens_hsa052040.71378796
102Serotonergic synapse_Homo sapiens_hsa047260.70119390
103Adipocytokine signaling pathway_Homo sapiens_hsa049200.68898978
104Oxidative phosphorylation_Homo sapiens_hsa001900.67845565
105GABAergic synapse_Homo sapiens_hsa047270.67293615
106Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.65271944
107Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.65024380
108RNA transport_Homo sapiens_hsa030130.63163139
109Central carbon metabolism in cancer_Homo sapiens_hsa052300.62595605
110Calcium signaling pathway_Homo sapiens_hsa040200.62331883
111Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.62287048
112Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61597934
113Thyroid hormone synthesis_Homo sapiens_hsa049180.60900350
114Alzheimers disease_Homo sapiens_hsa050100.58848294
115Parkinsons disease_Homo sapiens_hsa050120.58282036
116Synaptic vesicle cycle_Homo sapiens_hsa047210.56812334
117Basal cell carcinoma_Homo sapiens_hsa052170.55235166
118Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.53765538
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52801307
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.52734644
121Fatty acid elongation_Homo sapiens_hsa000620.52543941
122Sphingolipid metabolism_Homo sapiens_hsa006000.51024459
123p53 signaling pathway_Homo sapiens_hsa041150.47671974
124Bile secretion_Homo sapiens_hsa049760.47485728
125Salivary secretion_Homo sapiens_hsa049700.47016034
126Pancreatic secretion_Homo sapiens_hsa049720.46267782
127Metabolic pathways_Homo sapiens_hsa011000.45957070
128Systemic lupus erythematosus_Homo sapiens_hsa053220.45135740
129Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.44827359
130Ovarian steroidogenesis_Homo sapiens_hsa049130.42570140
131Legionellosis_Homo sapiens_hsa051340.40650366
132ABC transporters_Homo sapiens_hsa020100.40307720
133Gastric acid secretion_Homo sapiens_hsa049710.40023875
134AMPK signaling pathway_Homo sapiens_hsa041520.39984685
135Pentose and glucuronate interconversions_Homo sapiens_hsa000400.39811614
136Circadian entrainment_Homo sapiens_hsa047130.36474884
137Renin-angiotensin system_Homo sapiens_hsa046140.36295693
138Pyrimidine metabolism_Homo sapiens_hsa002400.36208584
139Sulfur metabolism_Homo sapiens_hsa009200.36147348
140VEGF signaling pathway_Homo sapiens_hsa043700.35620390
141Cell cycle_Homo sapiens_hsa041100.35464850
142Lysine degradation_Homo sapiens_hsa003100.35324195
143Endocytosis_Homo sapiens_hsa041440.33662944
144Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.33106742
145cAMP signaling pathway_Homo sapiens_hsa040240.31476968
146Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30970020
147Thyroid hormone signaling pathway_Homo sapiens_hsa049190.30685800
148Alcoholism_Homo sapiens_hsa050340.29465119
149Taste transduction_Homo sapiens_hsa047420.28579658
150Protein digestion and absorption_Homo sapiens_hsa049740.26673185
151Cocaine addiction_Homo sapiens_hsa050300.25507603
152Wnt signaling pathway_Homo sapiens_hsa043100.23247379
153Inositol phosphate metabolism_Homo sapiens_hsa005620.23030809
154HIF-1 signaling pathway_Homo sapiens_hsa040660.22877193
155Olfactory transduction_Homo sapiens_hsa047400.21521037
156Glutamatergic synapse_Homo sapiens_hsa047240.15598557
157Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.12466851
158Oxytocin signaling pathway_Homo sapiens_hsa049210.11101715

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