SPATS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1left/right pattern formation (GO:0060972)8.25391522
2axonemal dynein complex assembly (GO:0070286)7.55366356
3cilium or flagellum-dependent cell motility (GO:0001539)7.33693221
4left/right axis specification (GO:0070986)7.11536967
5cilium movement (GO:0003341)6.15076011
6primary alcohol catabolic process (GO:0034310)5.74705601
7vitamin transmembrane transport (GO:0035461)5.66079916
8epithelial cilium movement (GO:0003351)5.58107925
9retinal rod cell development (GO:0046548)5.55304605
10sperm capacitation (GO:0048240)5.53950424
11piRNA metabolic process (GO:0034587)5.51988293
12melanin biosynthetic process (GO:0042438)5.42950606
13regulation of cilium movement (GO:0003352)5.15321362
14centriole assembly (GO:0098534)5.10536935
15establishment of protein localization to mitochondrial membrane (GO:0090151)5.00108531
16response to xenobiotic stimulus (GO:0009410)4.97412958
17ethanol metabolic process (GO:0006067)4.97264889
18melanin metabolic process (GO:0006582)4.87695796
19synaptonemal complex organization (GO:0070193)4.84916030
20microtubule-based movement (GO:0007018)4.84236549
21diterpenoid biosynthetic process (GO:0016102)4.82758025
22epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.76027433
23axoneme assembly (GO:0035082)4.69607541
24regulation of mitochondrial translation (GO:0070129)4.68902423
25cellular component assembly involved in morphogenesis (GO:0010927)4.55924069
26secondary metabolite biosynthetic process (GO:0044550)4.54874211
27regulation of interleukin-5 production (GO:0032674)4.50149832
28male meiosis (GO:0007140)4.48164800
29pyrimidine-containing compound transmembrane transport (GO:0072531)4.45892151
30one-carbon compound transport (GO:0019755)4.44385212
31sperm motility (GO:0030317)4.43651536
32synaptonemal complex assembly (GO:0007130)4.36135526
33motile cilium assembly (GO:0044458)4.29427089
34GTP biosynthetic process (GO:0006183)4.27416211
35glomerular epithelial cell development (GO:0072310)4.24688633
36spermatid development (GO:0007286)4.24406555
37acrosome reaction (GO:0007340)4.15160589
38cell projection assembly (GO:0030031)4.04183587
39UTP biosynthetic process (GO:0006228)3.96441369
40regulation of interleukin-13 production (GO:0032656)3.93339293
41transcription elongation from RNA polymerase III promoter (GO:0006385)3.93260954
42termination of RNA polymerase III transcription (GO:0006386)3.93260954
43male meiosis I (GO:0007141)3.86763794
44tolerance induction (GO:0002507)3.82762264
45sperm-egg recognition (GO:0035036)3.77736921
46lung epithelium development (GO:0060428)3.77098293
47regulation of meiosis I (GO:0060631)3.74821200
48fusion of sperm to egg plasma membrane (GO:0007342)3.73562163
49binding of sperm to zona pellucida (GO:0007339)3.71986655
50rRNA catabolic process (GO:0016075)3.70959643
51maturation of 5.8S rRNA (GO:0000460)3.64227763
52establishment of apical/basal cell polarity (GO:0035089)3.61648338
53guanosine-containing compound biosynthetic process (GO:1901070)3.60851254
54sleep (GO:0030431)3.54128069
55chaperone-mediated protein complex assembly (GO:0051131)3.52978674
56lateral ventricle development (GO:0021670)3.52664169
57ethanol oxidation (GO:0006069)3.51332221
58protein localization to cilium (GO:0061512)3.49809151
59nucleoside diphosphate phosphorylation (GO:0006165)3.48325276
60negative regulation of humoral immune response (GO:0002921)3.46311702
61cytoplasmic microtubule organization (GO:0031122)3.46024113
62negative regulation of T cell differentiation in thymus (GO:0033085)3.41183502
63microtubule depolymerization (GO:0007019)3.39167396
64blastocyst development (GO:0001824)3.39019612
65meiosis I (GO:0007127)3.38347828
66UTP metabolic process (GO:0046051)3.36644202
67negative regulation of immunoglobulin mediated immune response (GO:0002890)3.33851050
68negative regulation of B cell mediated immunity (GO:0002713)3.33851050
69glutathione derivative biosynthetic process (GO:1901687)3.33640379
70glutathione derivative metabolic process (GO:1901685)3.33640379
71DNA methylation involved in gamete generation (GO:0043046)3.32012964
72intra-S DNA damage checkpoint (GO:0031573)3.30296272
73ventricular system development (GO:0021591)3.29678078
74meiotic nuclear division (GO:0007126)3.27884566
75IMP biosynthetic process (GO:0006188)3.27294930
76regulation of germinal center formation (GO:0002634)3.26702292
77retinoic acid metabolic process (GO:0042573)3.24288431
78ribosome biogenesis (GO:0042254)3.24215029
79cell-cell recognition (GO:0009988)3.21656402
80exogenous drug catabolic process (GO:0042738)3.17401013
81terpenoid biosynthetic process (GO:0016114)3.16905156
82positive regulation of tolerance induction (GO:0002645)3.16904234
83chromosome organization involved in meiosis (GO:0070192)3.14652495
84neuron cell-cell adhesion (GO:0007158)3.12996994
85negative regulation of inclusion body assembly (GO:0090084)3.12098759
86regulation of microtubule-based movement (GO:0060632)3.07498574
87negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.07274717
88mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.07139243
89female mating behavior (GO:0060180)3.05208434
90establishment of planar polarity (GO:0001736)3.05017238
91establishment of tissue polarity (GO:0007164)3.05017238
92retinal cone cell development (GO:0046549)3.01651841
93multicellular organism reproduction (GO:0032504)3.00924529
94regulation of inclusion body assembly (GO:0090083)2.99827050
95establishment of monopolar cell polarity (GO:0061162)2.99205139
96establishment or maintenance of monopolar cell polarity (GO:0061339)2.99205139
97determination of left/right symmetry (GO:0007368)2.96743818
98meiotic cell cycle (GO:0051321)2.93615066
99intraciliary transport (GO:0042073)2.93473587
100positive regulation of smoothened signaling pathway (GO:0045880)2.91170716
101microtubule-based process (GO:0007017)2.91056979
102acrosome assembly (GO:0001675)2.88999829
103determination of bilateral symmetry (GO:0009855)2.88949373
104negative regulation of JUN kinase activity (GO:0043508)2.85860358
105plasma membrane fusion (GO:0045026)2.85465328
106RNA capping (GO:0036260)2.83812725
1077-methylguanosine RNA capping (GO:0009452)2.83812725
108protein polyglutamylation (GO:0018095)2.83554341
109phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.82890202
110specification of symmetry (GO:0009799)2.81970951
111histone exchange (GO:0043486)2.81484631
112microtubule bundle formation (GO:0001578)2.80282328
113regulation of prostaglandin secretion (GO:0032306)2.78776381
114retinol metabolic process (GO:0042572)2.77384387
115energy coupled proton transport, down electrochemical gradient (GO:0015985)2.77114767
116ATP synthesis coupled proton transport (GO:0015986)2.77114767
117microtubule severing (GO:0051013)2.73314582
118positive regulation of prostaglandin secretion (GO:0032308)2.73135845
119histone H2A acetylation (GO:0043968)2.72908178
120spermatogenesis (GO:0007283)2.71900337
1217-methylguanosine mRNA capping (GO:0006370)2.71623477
122photoreceptor cell maintenance (GO:0045494)2.71538810
123single strand break repair (GO:0000012)2.71415477
124male gamete generation (GO:0048232)2.71396975
125ADP metabolic process (GO:0046031)2.70218493
126O-glycan processing (GO:0016266)2.70107860
127phosphatidylethanolamine biosynthetic process (GO:0006646)2.68527150
128excretion (GO:0007588)2.68477010
129cilium morphogenesis (GO:0060271)2.66324661
130central nervous system myelination (GO:0022010)2.64006661
131axon ensheathment in central nervous system (GO:0032291)2.64006661
132primary alcohol metabolic process (GO:0034308)2.61347364
133hyperosmotic salinity response (GO:0042538)2.60756601
134regulation of female receptivity (GO:0045924)2.60703661
135ribonucleoprotein complex biogenesis (GO:0022613)2.60373727
136cilium organization (GO:0044782)2.59833483
137germ cell development (GO:0007281)2.58994676
138CTP biosynthetic process (GO:0006241)2.58401245
139CTP metabolic process (GO:0046036)2.58401245
140mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.57841011
141multicellular organismal water homeostasis (GO:0050891)2.56997686
142purine nucleobase biosynthetic process (GO:0009113)2.56866698
143peptidyl-tyrosine autophosphorylation (GO:0038083)2.56556638
144cilium assembly (GO:0042384)2.54561978
145hydrogen peroxide biosynthetic process (GO:0050665)2.54398506
146calcium ion-dependent exocytosis (GO:0017156)2.54039454
147microtubule polymerization or depolymerization (GO:0031109)2.53834800
148neurotransmitter uptake (GO:0001504)2.53755675
149RNA localization (GO:0006403)2.53737427
150organelle assembly (GO:0070925)2.53476955
151carnitine metabolic process (GO:0009437)2.52723656
152regulation of spindle checkpoint (GO:0090231)2.52146735
153rRNA modification (GO:0000154)2.51461124
154phosphatidylethanolamine metabolic process (GO:0046337)2.51250600
155CDP-diacylglycerol biosynthetic process (GO:0016024)2.50879312
156regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.50644161
157gamete generation (GO:0007276)2.50192722
158spindle assembly involved in mitosis (GO:0090307)2.49967229
159purine nucleotide salvage (GO:0032261)2.47797954
160pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.47400190
161pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.46954025
162regulation of microtubule depolymerization (GO:0031114)2.46841592
163smoothened signaling pathway (GO:0007224)2.46417360
164IMP metabolic process (GO:0046040)2.46302741
165positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.45936377
166C4-dicarboxylate transport (GO:0015740)2.45164277
167centriole replication (GO:0007099)2.45107347
168positive regulation of icosanoid secretion (GO:0032305)2.44248183
169drug catabolic process (GO:0042737)2.42869572
170embryonic body morphogenesis (GO:0010172)2.40795703
171aldehyde catabolic process (GO:0046185)2.40722760

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.14538085
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.67709496
3EZH2_22144423_ChIP-Seq_EOC_Human3.97549767
4DROSHA_22980978_ChIP-Seq_HELA_Human3.40517747
5FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.91692468
6HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.57600712
7TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.56711870
8TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.50401273
9BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.49904539
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.49810591
11ESR1_20079471_ChIP-ChIP_T-47D_Human2.44306191
12GATA1_26923725_Chip-Seq_HPCs_Mouse2.28037702
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.25522205
14AHR_22903824_ChIP-Seq_MCF-7_Human2.05298437
15SMC4_20622854_ChIP-Seq_HELA_Human2.03244855
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.02852545
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.98443773
18ETS1_20019798_ChIP-Seq_JURKAT_Human1.90786346
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.88859007
20RBPJ_22232070_ChIP-Seq_NCS_Mouse1.88317233
21GATA1_22025678_ChIP-Seq_K562_Human1.83606083
22FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.82196389
23STAT1_20625510_ChIP-Seq_HELA_Human1.81977154
24MYC_18555785_ChIP-Seq_MESCs_Mouse1.81247665
25ARNT_22903824_ChIP-Seq_MCF-7_Human1.80852081
26SALL1_21062744_ChIP-ChIP_HESCs_Human1.76286074
27ELF1_20517297_ChIP-Seq_JURKAT_Human1.73296916
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73245684
29PIAS1_25552417_ChIP-Seq_VCAP_Human1.69874126
30AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.68868943
31SMRT_27268052_Chip-Seq_Bcells_Human1.68667946
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66922255
33VDR_22108803_ChIP-Seq_LS180_Human1.66344915
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.64921283
35TP63_23658742_ChIP-Seq_EP156T_Human1.63241541
36GABP_17652178_ChIP-ChIP_JURKAT_Human1.62540355
37KLF5_25053715_ChIP-Seq_YYC3_Human1.61370512
38FOXM1_26456572_ChIP-Seq_MCF-7_Human1.61200316
39CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.60590502
40TAF15_26573619_Chip-Seq_HEK293_Human1.60409482
41* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58303496
42RBPJ_21746931_ChIP-Seq_IB4_Human1.54113132
43CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.54111773
44E2F4_17652178_ChIP-ChIP_JURKAT_Human1.53071280
45PHF8_20622853_ChIP-Seq_HELA_Human1.52159302
46MYC_19079543_ChIP-ChIP_MESCs_Mouse1.51520122
47YY1_22570637_ChIP-Seq_MALME-3M_Human1.51109380
48CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.50680804
49ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.50504126
50NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.50454978
51PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.50363349
52NR3C1_21868756_ChIP-Seq_MCF10A_Human1.50002024
53CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.49979725
54FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.49553559
55HNFA_21074721_ChIP-Seq_CACO-2_Human1.46985168
56TP63_22573176_ChIP-Seq_HFKS_Human1.46857940
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46797720
58RUNX1_27514584_Chip-Seq_MCF-7_Human1.45653004
59CREB1_15753290_ChIP-ChIP_HEK293T_Human1.44725636
60AR_21572438_ChIP-Seq_LNCaP_Human1.44468683
61MYC_19030024_ChIP-ChIP_MESCs_Mouse1.43972852
62* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.43835537
63TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.43662739
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.43342631
65PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.42783605
66SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.41875519
67FUS_26573619_Chip-Seq_HEK293_Human1.41214894
68MYC_18358816_ChIP-ChIP_MESCs_Mouse1.38889754
69REST_21632747_ChIP-Seq_MESCs_Mouse1.38846770
70TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38324802
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37464572
72* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.36437345
73TP53_18474530_ChIP-ChIP_U2OS_Human1.36376370
74CBX2_22325352_ChIP-Seq_293T-Rex_Human1.33671977
75YY1_21170310_ChIP-Seq_MESCs_Mouse1.33263521
76TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32707570
77POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32690001
78ELF1_17652178_ChIP-ChIP_JURKAT_Human1.32469875
79SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.30699497
80E2F7_22180533_ChIP-Seq_HELA_Human1.30032361
81MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.28449628
82GATA6_21074721_ChIP-Seq_CACO-2_Human1.27841415
83SMAD4_21741376_ChIP-Seq_EPCs_Human1.27680089
84NFYA_21822215_ChIP-Seq_K562_Human1.27529015
85RAD21_21589869_ChIP-Seq_MESCs_Mouse1.27238523
86SOX2_27498859_Chip-Seq_STOMACH_Mouse1.27119231
87VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.26868144
88CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26685897
89MYCN_18555785_ChIP-Seq_MESCs_Mouse1.26572606
90* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25771423
91POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.25131478
92EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.24693020
93P63_26484246_Chip-Seq_KERATINOCYTES_Human1.24640430
94SOX2_16153702_ChIP-ChIP_HESCs_Human1.24302514
95CEBPB_22108803_ChIP-Seq_LS180_Human1.23952441
96CTCF_20526341_ChIP-Seq_ESCs_Human1.23835183
97GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.23555174
98* TDRD3_21172665_ChIP-Seq_MCF-7_Human1.23399750
99KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.22601362
100ERG_20517297_ChIP-Seq_VCAP_Human1.21735589
101SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21144457
102CTNNB1_20460455_ChIP-Seq_HCT116_Human1.21139073
103FOXA1_25552417_ChIP-Seq_VCAP_Human1.21088716
104NFYB_21822215_ChIP-Seq_K562_Human1.20272912
105SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.19753132
106STAT3_23295773_ChIP-Seq_U87_Human1.18430365
107SMAD3_21741376_ChIP-Seq_EPCs_Human1.17788678
108SOX2_21211035_ChIP-Seq_LN229_Human1.17716467
109FLI1_27457419_Chip-Seq_LIVER_Mouse1.17304128
110GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16811066
111NANOG_18555785_ChIP-Seq_MESCs_Mouse1.13560736
112CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.13381604
113STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.12031198
114* PHF8_20622854_ChIP-Seq_HELA_Human1.11589406
115* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.10887792
116CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10550121
117ZNF217_24962896_ChIP-Seq_MCF-7_Human1.10174992
118CBP_20019798_ChIP-Seq_JUKART_Human1.10086923
119IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10086923
120FOXA1_25329375_ChIP-Seq_VCAP_Human1.09569426
121FOXA1_27270436_Chip-Seq_PROSTATE_Human1.09569426
122IRF1_19129219_ChIP-ChIP_H3396_Human1.08675759
123AUTS2_25519132_ChIP-Seq_293T-REX_Human1.08171327
124GATA4_25053715_ChIP-Seq_YYC3_Human1.08134311
125EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.07908265
126PCGF2_27294783_Chip-Seq_ESCs_Mouse1.07688548
127P68_20966046_ChIP-Seq_HELA_Human1.07381067
128RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.07312953
129ESR2_21235772_ChIP-Seq_MCF-7_Human1.06593385
130NFE2_27457419_Chip-Seq_LIVER_Mouse1.06494526
131THAP11_20581084_ChIP-Seq_MESCs_Mouse1.06151337
132SMAD4_21741376_ChIP-Seq_HESCs_Human1.06058553
133NCOR_22424771_ChIP-Seq_293T_Human1.05937257
134ESR1_21235772_ChIP-Seq_MCF-7_Human1.05562643
135TBL1_22424771_ChIP-Seq_293T_Human1.05302940
136GATA1_19941826_ChIP-Seq_K562_Human1.04872455
137TCF4_22108803_ChIP-Seq_LS180_Human1.04844762
138* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.02915275
139KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.02571524
140KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.02571524
141KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.02571524
142MYC_18940864_ChIP-ChIP_HL60_Human1.02560714
143ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.02276045
144BMI1_23680149_ChIP-Seq_NPCS_Mouse1.01835792
145FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.01665794
146E2F1_20622854_ChIP-Seq_HELA_Human1.01582895
147FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.01027949
148RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00614130
149AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00139405
150PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99902106
151FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99535632
152E2F1_17053090_ChIP-ChIP_MCF-7_Human0.99296365
153RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.99010141
154SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98870266
155* SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.97557948
156RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96262615
157KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.95666273
158VDR_23849224_ChIP-Seq_CD4+_Human0.95378017
159ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95112226
160RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.94392610
161RNF2_27304074_Chip-Seq_NSC_Mouse0.92861361
162TAL1_26923725_Chip-Seq_HPCs_Mouse0.91971510
163SUZ12_27294783_Chip-Seq_NPCs_Mouse0.91855414
164TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91759606
165NANOG_18555785_Chip-Seq_ESCs_Mouse0.91449199
166GBX2_23144817_ChIP-Seq_PC3_Human0.90103888
167NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.89952801
168ETV1_20927104_ChIP-Seq_GIST48_Human0.89611682
169DCP1A_22483619_ChIP-Seq_HELA_Human0.89303429
170YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.88691108
171SMAD4_21799915_ChIP-Seq_A2780_Human0.87487475
172P300_19829295_ChIP-Seq_ESCs_Human0.87335831
173POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.86992228
174CBX2_27304074_Chip-Seq_ESCs_Mouse0.86325520
175KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.85665861
176STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.85428749
177BCAT_22108803_ChIP-Seq_LS180_Human0.83635433
178UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83025133
179ERG_21242973_ChIP-ChIP_JURKAT_Human0.81777406
180CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.81669083
181* REST_18959480_ChIP-ChIP_MESCs_Mouse0.81606238
182ELK4_26923725_Chip-Seq_MESODERM_Mouse0.81589807
183PADI4_21655091_ChIP-ChIP_MCF-7_Human0.81124427
184HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.80743689
185E2F1_18555785_ChIP-Seq_MESCs_Mouse0.79885747
186XRN2_22483619_ChIP-Seq_HELA_Human0.79880455

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000372_irregular_coat_pigmentation5.32366714
2MP0008875_abnormal_xenobiotic_pharmacok5.02791325
3MP0005377_hearing/vestibular/ear_phenot4.81027357
4MP0003878_abnormal_ear_physiology4.81027357
5MP0005410_abnormal_fertilization4.76171376
6MP0002132_abnormal_respiratory_system4.38551154
7MP0005408_hypopigmentation4.24178415
8MP0003136_yellow_coat_color3.36892515
9MP0001529_abnormal_vocalization3.10646381
10MP0002138_abnormal_hepatobiliary_system2.95703364
11MP0002653_abnormal_ependyma_morphology2.87499892
12MP0008877_abnormal_DNA_methylation2.82873649
13MP0002277_abnormal_respiratory_mucosa2.80085888
14MP0005075_abnormal_melanosome_morpholog2.71842677
15MP0004043_abnormal_pH_regulation2.67472811
16MP0006292_abnormal_olfactory_placode2.66453082
17MP0001929_abnormal_gametogenesis2.57372811
18MP0003698_abnormal_male_reproductive2.55425153
19MP0001440_abnormal_grooming_behavior2.42311609
20MP0000015_abnormal_ear_pigmentation2.36899738
21MP0008057_abnormal_DNA_replication2.28365154
22MP0003880_abnormal_central_pattern2.21359379
23MP0002210_abnormal_sex_determination2.14644606
24MP0009780_abnormal_chondrocyte_physiolo2.13832505
25MP0001348_abnormal_lacrimal_gland2.09579909
26MP0001485_abnormal_pinna_reflex2.07800750
27MP0005670_abnormal_white_adipose2.07331304
28MP0001324_abnormal_eye_pigmentation2.02674971
29MP0009046_muscle_twitch2.00604338
30MP0006276_abnormal_autonomic_nervous1.95405591
31MP0000678_abnormal_parathyroid_gland1.89072246
32MP0002736_abnormal_nociception_after1.84933173
33MP0006072_abnormal_retinal_apoptosis1.82815002
34MP0003635_abnormal_synaptic_transmissio1.81694895
35MP0003718_maternal_effect1.81316132
36MP0010234_abnormal_vibrissa_follicle1.80843359
37MP0004859_abnormal_synaptic_plasticity1.80312450
38MP0002064_seizures1.72297527
39MP0002572_abnormal_emotion/affect_behav1.71333600
40MP0001145_abnormal_male_reproductive1.69173604
41MP0003111_abnormal_nucleus_morphology1.66711053
42MP0004019_abnormal_vitamin_homeostasis1.66079039
43MP0001968_abnormal_touch/_nociception1.66075683
44MP0002095_abnormal_skin_pigmentation1.65859387
45MP0005257_abnormal_intraocular_pressure1.65477658
46MP0004381_abnormal_hair_follicle1.64712084
47MP0010678_abnormal_skin_adnexa1.64237796
48MP0008789_abnormal_olfactory_epithelium1.60928505
49MP0004270_analgesia1.60824305
50MP0003950_abnormal_plasma_membrane1.60705519
51MP0002160_abnormal_reproductive_system1.57426588
52MP0001984_abnormal_olfaction1.56954166
53MP0004742_abnormal_vestibular_system1.56931371
54MP0000371_diluted_coat_color1.56786263
55MP0002272_abnormal_nervous_system1.56781101
56MP0009745_abnormal_behavioral_response1.56626467
57MP0000383_abnormal_hair_follicle1.56412505
58MP0005253_abnormal_eye_physiology1.53434135
59MP0000566_synostosis1.51907602
60MP0000653_abnormal_sex_gland1.50271140
61MP0001188_hyperpigmentation1.49450941
62MP0002168_other_aberrant_phenotype1.45734385
63MP0003123_paternal_imprinting1.45344400
64MP0001905_abnormal_dopamine_level1.44500471
65MP0002063_abnormal_learning/memory/cond1.44312829
66MP0002161_abnormal_fertility/fecundity1.42981860
67MP0002734_abnormal_mechanical_nocicepti1.41476099
68MP0005083_abnormal_biliary_tract1.41137489
69MP0005165_increased_susceptibility_to1.38805807
70MP0000778_abnormal_nervous_system1.37287360
71MP0005379_endocrine/exocrine_gland_phen1.34906404
72MP0001765_abnormal_ion_homeostasis1.34850741
73MP0002102_abnormal_ear_morphology1.28375123
74MP0001963_abnormal_hearing_physiology1.23771294
75MP0003646_muscle_fatigue1.23290377
76MP0002067_abnormal_sensory_capabilities1.22871579
77MP0002184_abnormal_innervation1.20927092
78MP0004957_abnormal_blastocyst_morpholog1.20654206
79MP0005248_abnormal_Harderian_gland1.19660088
80MP0010094_abnormal_chromosome_stability1.19474486
81MP0001661_extended_life_span1.19132808
82MP0001486_abnormal_startle_reflex1.18340921
83MP0002557_abnormal_social/conspecific_i1.17619638
84MP0003656_abnormal_erythrocyte_physiolo1.17567676
85MP0002822_catalepsy1.14795172
86MP0001970_abnormal_pain_threshold1.11832981
87MP0005395_other_phenotype1.11576474
88MP0005551_abnormal_eye_electrophysiolog1.09063432
89MP0001346_abnormal_lacrimal_gland1.08356320
90MP0000049_abnormal_middle_ear1.05739979
91MP0003693_abnormal_embryo_hatching1.05728192
92MP0004142_abnormal_muscle_tone1.04385475
93MP0002752_abnormal_somatic_nervous1.03332610
94MP0003861_abnormal_nervous_system1.02107673
95MP0003786_premature_aging1.00867361
96MP0002909_abnormal_adrenal_gland1.00783214
97MP0003936_abnormal_reproductive_system1.00509419
98MP0005636_abnormal_mineral_homeostasis0.99208188
99MP0002882_abnormal_neuron_morphology0.98869043
100MP0004133_heterotaxia0.98060539
101MP0002152_abnormal_brain_morphology0.97888536
102MP0001502_abnormal_circadian_rhythm0.96263996
103MP0006035_abnormal_mitochondrial_morpho0.95975963
104MP0005389_reproductive_system_phenotype0.93926538
105MP0000026_abnormal_inner_ear0.93521779
106MP0002090_abnormal_vision0.92845192
107MP0009250_abnormal_appendicular_skeleto0.90616572
108MP0005386_behavior/neurological_phenoty0.90407726
109MP0004924_abnormal_behavior0.90407726
110MP0003806_abnormal_nucleotide_metabolis0.89012358
111MP0003634_abnormal_glial_cell0.88237381
112MP0009643_abnormal_urine_homeostasis0.88237227
113MP0002733_abnormal_thermal_nociception0.88099391
114MP0000631_abnormal_neuroendocrine_gland0.86587435
115MP0002249_abnormal_larynx_morphology0.86462291
116MP0000747_muscle_weakness0.84927355
117MP0008058_abnormal_DNA_repair0.84677134
118MP0008932_abnormal_embryonic_tissue0.84228830
119MP0005171_absent_coat_pigmentation0.83612629
120MP0002163_abnormal_gland_morphology0.83428233
121MP0002066_abnormal_motor_capabilities/c0.83184407
122MP0000751_myopathy0.81611219
123MP0000358_abnormal_cell_content/0.81150411
124MP0001542_abnormal_bone_strength0.80574453
125MP0001501_abnormal_sleep_pattern0.79179475
126MP0002233_abnormal_nose_morphology0.78969766
127MP0003315_abnormal_perineum_morphology0.78051237
128MP0005409_darkened_coat_color0.78001700
129MP0004145_abnormal_muscle_electrophysio0.77727677
130MP0000681_abnormal_thyroid_gland0.76777470
131MP0003631_nervous_system_phenotype0.76460924
132MP0002282_abnormal_trachea_morphology0.76390249
133MP0003632_abnormal_nervous_system0.74538946
134MP0002229_neurodegeneration0.74126092
135MP0003329_amyloid_beta_deposits0.74125838
136MP0000955_abnormal_spinal_cord0.74067959
137MP0004811_abnormal_neuron_physiology0.72488664
138MP0005499_abnormal_olfactory_system0.71518815
139MP0005394_taste/olfaction_phenotype0.71518815
140MP0005623_abnormal_meninges_morphology0.69008228
141MP0003879_abnormal_hair_cell0.68994623
142MP0005391_vision/eye_phenotype0.68318043
143MP0002136_abnormal_kidney_physiology0.67477200
144MP0002735_abnormal_chemical_nociception0.64090059
145MP0009765_abnormal_xenobiotic_induced0.63294277
146MP0006036_abnormal_mitochondrial_physio0.63032204
147MP0005195_abnormal_posterior_eye0.62469887
148MP0002075_abnormal_coat/hair_pigmentati0.57018625
149MP0005319_abnormal_enzyme/_coenzyme0.56211625
150MP0005645_abnormal_hypothalamus_physiol0.52680103
151MP0003172_abnormal_lysosome_physiology0.51758436
152MP0002638_abnormal_pupillary_reflex0.50460282
153MP0001186_pigmentation_phenotype0.46331551
154MP0002098_abnormal_vibrissa_morphology0.46305644
155MP0005187_abnormal_penis_morphology0.46167656
156MP0001849_ear_inflammation0.46048787
157MP0005310_abnormal_salivary_gland0.41763855
158MP0005397_hematopoietic_system_phenotyp0.41490607
159MP0001545_abnormal_hematopoietic_system0.41490607
160MP0004885_abnormal_endolymph0.40674809
161MP0003453_abnormal_keratinocyte_physiol0.38781873
162MP0005174_abnormal_tail_pigmentation0.38221228
163MP0004264_abnormal_extraembryonic_tissu0.37425078
164MP0002938_white_spotting0.37042718
165MP0002876_abnormal_thyroid_physiology0.36341204
166MP0005220_abnormal_exocrine_pancreas0.36277421
167MP0000465_gastrointestinal_hemorrhage0.35907752
168MP0010155_abnormal_intestine_physiology0.35445528

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.36458773
2Nasal polyposis (HP:0100582)6.93925429
3Abnormal respiratory motile cilium physiology (HP:0012261)6.28188534
4Rhinitis (HP:0012384)6.09524946
5Abnormal respiratory epithelium morphology (HP:0012253)6.01137143
6Abnormal respiratory motile cilium morphology (HP:0005938)6.01137143
7Abnormality of the nasal mucosa (HP:0000433)5.74428245
8Dynein arm defect of respiratory motile cilia (HP:0012255)5.29634862
9Absent/shortened dynein arms (HP:0200106)5.29634862
10Abnormal ciliary motility (HP:0012262)5.21077831
11Recurrent sinusitis (HP:0011108)4.40233620
12Bronchitis (HP:0012387)4.34806418
13Median cleft lip (HP:0000161)4.02829835
14Recurrent otitis media (HP:0000403)3.75999756
15Chronic bronchitis (HP:0004469)3.63383489
16Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.58900509
17Degeneration of the lateral corticospinal tracts (HP:0002314)3.58900509
18Medial flaring of the eyebrow (HP:0010747)3.58380757
19Occipital encephalocele (HP:0002085)3.58351228
20Male infertility (HP:0003251)3.56960787
21Chronic sinusitis (HP:0011109)3.55699746
22Irregular epiphyses (HP:0010582)3.54891486
23Chronic hepatic failure (HP:0100626)3.38503828
24Carpal bone hypoplasia (HP:0001498)3.04423095
25Infertility (HP:0000789)3.00331413
26Nephronophthisis (HP:0000090)2.90643577
27Hyperactive renin-angiotensin system (HP:0000841)2.85261106
28Abnormality of the corticospinal tract (HP:0002492)2.82234810
29Rectal fistula (HP:0100590)2.78477101
30Rectovaginal fistula (HP:0000143)2.78477101
31Cystic liver disease (HP:0006706)2.78380650
32Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.77660868
33Pancreatic fibrosis (HP:0100732)2.76872422
34Atelectasis (HP:0100750)2.69899239
35Bronchiectasis (HP:0002110)2.66022812
36Chronic otitis media (HP:0000389)2.63585147
37Ankle clonus (HP:0011448)2.61839084
38Supernumerary spleens (HP:0009799)2.60131492
39Absent epiphyses (HP:0010577)2.57209650
40Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.57209650
41Impulsivity (HP:0100710)2.54813431
42Absent rod-and cone-mediated responses on ERG (HP:0007688)2.54597751
43Gait imbalance (HP:0002141)2.53258810
44Atonic seizures (HP:0010819)2.45671785
45Congenital primary aphakia (HP:0007707)2.43114085
46Absent hand (HP:0004050)2.39797311
47Acute necrotizing encephalopathy (HP:0006965)2.33218971
48Nephrogenic diabetes insipidus (HP:0009806)2.30785964
49Flattened epiphyses (HP:0003071)2.29754909
50Hypoplasia of the capital femoral epiphysis (HP:0003090)2.29108664
51Small epiphyses (HP:0010585)2.28153698
52Metaphyseal dysplasia (HP:0100255)2.26360768
53Excessive salivation (HP:0003781)2.25318584
54Drooling (HP:0002307)2.25318584
55Abnormality of the labia minora (HP:0012880)2.25188579
56Short tibia (HP:0005736)2.24445791
57Bell-shaped thorax (HP:0001591)2.23528070
58Flat capital femoral epiphysis (HP:0003370)2.20112893
59Intestinal fistula (HP:0100819)2.19243829
60Vaginal fistula (HP:0004320)2.14966385
61Genu varum (HP:0002970)2.12928423
62Fibular hypoplasia (HP:0003038)2.11270348
63Morphological abnormality of the pyramidal tract (HP:0002062)2.10734904
64Postaxial hand polydactyly (HP:0001162)2.10056714
65Pancreatic cysts (HP:0001737)2.09907842
66Epiphyseal dysplasia (HP:0002656)2.06358832
67Genital tract atresia (HP:0001827)2.05816559
68Abnormality of midbrain morphology (HP:0002418)2.03816133
69Molar tooth sign on MRI (HP:0002419)2.03816133
70Facial cleft (HP:0002006)2.00615270
71Aplasia/Hypoplasia of the tibia (HP:0005772)1.97970227
72Short femoral neck (HP:0100864)1.97604076
73Abnormality of the epiphysis of the femoral head (HP:0010574)1.96721993
74Abnormality of the renal medulla (HP:0100957)1.96015784
75Transposition of the great arteries (HP:0001669)1.95990865
76Abnormal connection of the cardiac segments (HP:0011545)1.95990865
77Abnormal ventriculo-arterial connection (HP:0011563)1.95990865
78True hermaphroditism (HP:0010459)1.95218137
79Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.94854385
80Abnormality of femoral epiphyses (HP:0006499)1.94854385
81Hyperkalemia (HP:0002153)1.94587866
82Recurrent bronchitis (HP:0002837)1.94339604
83Aplasia/hypoplasia of the humerus (HP:0006507)1.93090762
84Split foot (HP:0001839)1.92704255
85Focal motor seizures (HP:0011153)1.91677352
86Clonus (HP:0002169)1.91138338
87Follicular hyperkeratosis (HP:0007502)1.90713631
88CNS hypomyelination (HP:0003429)1.90554694
89Anencephaly (HP:0002323)1.89931741
90Abnormal mitochondria in muscle tissue (HP:0008316)1.89352687
91Poor coordination (HP:0002370)1.88392548
92Aplasia/Hypoplasia of the tongue (HP:0010295)1.88283341
93Abnormality of the femoral head (HP:0003368)1.88161210
94Hypothermia (HP:0002045)1.87849683
95Aplasia/Hypoplasia of the fibula (HP:0006492)1.87804758
96Absent radius (HP:0003974)1.86914062
97Postaxial foot polydactyly (HP:0001830)1.86719447
98Tubulointerstitial nephritis (HP:0001970)1.84703932
99Abnormal rod and cone electroretinograms (HP:0008323)1.83565635
100Decreased circulating renin level (HP:0003351)1.83522182
101Microglossia (HP:0000171)1.83101432
102Male pseudohermaphroditism (HP:0000037)1.82036865
103Tubular atrophy (HP:0000092)1.81844943
104Decreased central vision (HP:0007663)1.81526091
105Abnormal spermatogenesis (HP:0008669)1.79359108
106Absent forearm bone (HP:0003953)1.78264445
107Aplasia involving forearm bones (HP:0009822)1.78264445
108Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.76721230
109Retinal dysplasia (HP:0007973)1.74238930
110Nephropathy (HP:0000112)1.73779150
111Abnormality of the vertebral endplates (HP:0005106)1.73480743
112Spastic gait (HP:0002064)1.72189469
113Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.72183111
114Decreased activity of mitochondrial respiratory chain (HP:0008972)1.72183111
115Delusions (HP:0000746)1.71882664
116Sensory axonal neuropathy (HP:0003390)1.71864777
117Ocular albinism (HP:0001107)1.71178374
118Adrenal hypoplasia (HP:0000835)1.70040084
119Short humerus (HP:0005792)1.69265623
120Abnormality of abdominal situs (HP:0011620)1.67402702
121Abdominal situs inversus (HP:0003363)1.67402702
122Focal seizures (HP:0007359)1.66657571
123Vaginal atresia (HP:0000148)1.65804768
124Leukodystrophy (HP:0002415)1.65609346
125Aplasia/Hypoplasia of the macula (HP:0008059)1.65461373
126Oculomotor apraxia (HP:0000657)1.63673781
127Progressive macrocephaly (HP:0004481)1.62884129
128Cone-rod dystrophy (HP:0000548)1.62795173
129Renal salt wasting (HP:0000127)1.62363189
130Sclerocornea (HP:0000647)1.60864543
131Congenital hepatic fibrosis (HP:0002612)1.60823019
132Furrowed tongue (HP:0000221)1.57889583
133Aplasia/Hypoplasia affecting the retina (HP:0008061)1.53009130
134Asplenia (HP:0001746)1.50397030
135Tubulointerstitial abnormality (HP:0001969)1.48912107
136Aplasia/Hypoplasia of the spleen (HP:0010451)1.47310363
137Hyperaldosteronism (HP:0000859)1.43009924
138Preaxial hand polydactyly (HP:0001177)1.42993908
139Iris hypopigmentation (HP:0007730)1.42280641
140Absent frontal sinuses (HP:0002688)1.41046611
141Blue irides (HP:0000635)1.38632779
142Abnormality of chloride homeostasis (HP:0011422)1.38139475
143Short thorax (HP:0010306)1.37729986
144Hypoplasia of the fovea (HP:0007750)1.35861432
145Aplasia/Hypoplasia of the fovea (HP:0008060)1.35861432
146Hypokalemic alkalosis (HP:0001949)1.28853997
147Lip pit (HP:0100267)1.27514125
148Hand muscle atrophy (HP:0009130)1.26709167
149Renal dysplasia (HP:0000110)1.26643604
150Abnormality of renin-angiotensin system (HP:0000847)1.23623782
151Stage 5 chronic kidney disease (HP:0003774)1.18003624
152Abnormality of permanent molar morphology (HP:0011071)1.17842201
153Abnormality of the dental root (HP:0006486)1.17842201
154Taurodontia (HP:0000679)1.17842201
155Bony spicule pigmentary retinopathy (HP:0007737)1.16476296
156Dyschromatopsia (HP:0007641)1.16082815
157Bile duct proliferation (HP:0001408)1.15045816
158Abnormal biliary tract physiology (HP:0012439)1.15045816
159Popliteal pterygium (HP:0009756)1.14867553
160Abnormal drinking behavior (HP:0030082)1.14849436
161Polydipsia (HP:0001959)1.14849436
162Abnormality of the fovea (HP:0000493)1.14447210
163Fetal akinesia sequence (HP:0001989)1.12946202
164Abnormality of the dental pulp (HP:0006479)1.10132452
165Hyponatremia (HP:0002902)1.09977934
166Abnormality of macular pigmentation (HP:0008002)1.09102448
167Abnormality of molar morphology (HP:0011070)1.07948193
168Abnormality of molar (HP:0011077)1.07948193
169Hypopigmentation of the fundus (HP:0007894)1.07164433
170Abnormality of dentin (HP:0010299)1.07099849

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK4.05509611
2MST1R3.51479035
3PDK43.42488770
4PDK33.42488770
5AKT33.13311476
6CASK3.09881712
7WEE12.70645818
8TESK22.36261018
9MST42.27856300
10PDK22.20931043
11PRKD32.14811710
12BUB12.04829388
13PLK21.79922674
14MAP3K31.68236825
15MAPKAPK31.64335039
16WNK31.54438825
17ACVR1B1.51265817
18BRAF1.50772500
19CDK191.48408125
20EPHA41.47486218
21TESK11.47319841
22MAP3K121.46758727
23OXSR11.46690826
24TSSK61.45547722
25NME11.38831804
26PLK31.38567017
27FRK1.38291340
28STK241.37744106
29PLK41.36742416
30CDC71.34064033
31MET1.33070195
32VRK11.32503795
33MAPK151.30753884
34SRPK11.26377691
35EEF2K1.26328327
36MARK11.26213901
37PLK11.22669528
38PRKCG1.19595977
39STK381.18838788
40TTK1.18485326
41YES11.18068647
42GRK61.17647027
43MAPK131.15893801
44MKNK21.15435656
45MAP3K81.14771861
46AURKA1.14285078
47PTK2B1.12010838
48STK101.11558301
49CSK1.10501066
50BCR1.07783618
51EPHA21.06958549
52ARAF1.06594892
53PAK31.03263512
54LRRK21.01186642
55INSRR0.99031149
56NTRK20.95821852
57CCNB10.94304379
58STK390.93287136
59TYRO30.90573276
60GRK50.82006204
61MKNK10.81018132
62TGFBR20.79915165
63PHKG10.78823827
64PHKG20.78823827
65PASK0.78286542
66PINK10.77425462
67STK38L0.75309165
68STK160.73475446
69CHEK20.72224652
70SGK2230.71531519
71SGK4940.71531519
72SGK20.71254080
73FGR0.71140126
74FER0.70442548
75PRKCH0.69174145
76EIF2AK10.68501558
77LMTK20.67416885
78PAK10.66580351
79ZAP700.65981857
80ZAK0.65518176
81GRK10.65330304
82SMG10.65029115
83MAP3K70.64584539
84MAP3K20.64220642
85CHEK10.63758770
86PDPK10.63514555
87PRKAA20.62968309
88NTRK30.62452512
89NTRK10.61745161
90NEK20.61511255
91MELK0.60676135
92MAP2K70.60495370
93TBK10.59800660
94LATS20.58241000
95MAP3K40.58104656
96IRAK20.57392278
97ERBB20.57179117
98MAP2K20.56455132
99DYRK1A0.56078334
100DYRK20.55971136
101CDK120.55954796
102AKT20.55452368
103MINK10.53667517
104CSNK2A20.53185744
105CAMK1G0.53054236
106ERBB30.52814199
107ICK0.52365298
108NEK60.51544656
109CAMKK20.51358371
110PRKCI0.51262681
111MAP3K90.51116362
112ADRBK10.50658033
113CSNK1E0.50530867
114NLK0.50528009
115BRSK20.50009675
116MARK20.49587516
117BMPR1B0.48610377
118TLK10.48576822
119WNK40.48286884
120CAMKK10.47698418
121CDK20.47524967
122CSNK1G10.47497833
123ADRBK20.46968765
124MAPKAPK50.46470421
125CAMK2A0.45408743
126FGFR20.45228953
127BMPR20.45216935
128PRKCD0.45209069
129ALK0.42894097
130ROCK20.42459462
131CSNK2A10.41796915
132RIPK40.41479654
133ATR0.39422366
134MAPK100.38842988
135UHMK10.38728598
136MAP4K20.38696036
137DDR20.38513032
138PDK10.38276747
139CDK10.38141697
140PRKG10.36528716
141TRPM70.36433699
142RPS6KB20.34923465
143TYK20.34102167
144SGK10.31598257
145EPHB10.29907309
146EGFR0.28424113
147CDK60.28220341
148PAK40.27721238
149CAMK2G0.26655719
150MUSK0.26427464
151FGFR30.26426473
152STK30.25049354
153RPS6KA20.25007376
154PRKACA0.24742495
155DYRK1B0.23702441
156ABL20.23242814
157IGF1R0.22278291
158ERBB40.20344654
159IRAK10.18560329
160MATK0.18164793
161PRKCA0.17458340
162PRKCZ0.16783293
163PRKCQ0.15965700
164PRKD10.15560456

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009805.56464535
2Vitamin B6 metabolism_Homo sapiens_hsa007504.75683010
3Chemical carcinogenesis_Homo sapiens_hsa052044.53399786
4Tyrosine metabolism_Homo sapiens_hsa003504.49268140
5Drug metabolism - cytochrome P450_Homo sapiens_hsa009824.46844568
6Phenylalanine metabolism_Homo sapiens_hsa003604.41051252
7RNA polymerase_Homo sapiens_hsa030204.38548093
8Histidine metabolism_Homo sapiens_hsa003403.86726818
9Proteasome_Homo sapiens_hsa030503.55385626
10Oxidative phosphorylation_Homo sapiens_hsa001903.14559354
11Huntingtons disease_Homo sapiens_hsa050162.77013036
12beta-Alanine metabolism_Homo sapiens_hsa004102.65170898
13Retinol metabolism_Homo sapiens_hsa008302.48214078
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.45869685
15Parkinsons disease_Homo sapiens_hsa050122.34544305
16Caffeine metabolism_Homo sapiens_hsa002322.33842920
17RNA transport_Homo sapiens_hsa030132.26931217
18Sphingolipid metabolism_Homo sapiens_hsa006002.26819368
19Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.20819709
20Collecting duct acid secretion_Homo sapiens_hsa049662.18415150
21Nicotine addiction_Homo sapiens_hsa050332.17135694
22Pyrimidine metabolism_Homo sapiens_hsa002402.01270107
23Oocyte meiosis_Homo sapiens_hsa041141.89963129
24Spliceosome_Homo sapiens_hsa030401.88161315
25Homologous recombination_Homo sapiens_hsa034401.84345238
26Alzheimers disease_Homo sapiens_hsa050101.83998529
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.70696197
28Purine metabolism_Homo sapiens_hsa002301.70664570
29Ribosome_Homo sapiens_hsa030101.66484680
30Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.61451377
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.59169844
32Steroid hormone biosynthesis_Homo sapiens_hsa001401.57926824
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.57481180
34Fatty acid degradation_Homo sapiens_hsa000711.47702575
35ABC transporters_Homo sapiens_hsa020101.47072132
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.46521761
37Pentose and glucuronate interconversions_Homo sapiens_hsa000401.44354314
38DNA replication_Homo sapiens_hsa030301.39023853
39Olfactory transduction_Homo sapiens_hsa047401.38714786
40Amphetamine addiction_Homo sapiens_hsa050311.38416785
41Pentose phosphate pathway_Homo sapiens_hsa000301.36678731
42Cardiac muscle contraction_Homo sapiens_hsa042601.36270414
43mRNA surveillance pathway_Homo sapiens_hsa030151.36081221
44Mismatch repair_Homo sapiens_hsa034301.35854686
45Synaptic vesicle cycle_Homo sapiens_hsa047211.35687009
46Fanconi anemia pathway_Homo sapiens_hsa034601.32981164
47Starch and sucrose metabolism_Homo sapiens_hsa005001.32332061
48Nucleotide excision repair_Homo sapiens_hsa034201.29403827
49Basal transcription factors_Homo sapiens_hsa030221.28678115
50Primary bile acid biosynthesis_Homo sapiens_hsa001201.23349053
51Glycosaminoglycan degradation_Homo sapiens_hsa005311.23119095
52Glutamatergic synapse_Homo sapiens_hsa047241.22386308
53GABAergic synapse_Homo sapiens_hsa047271.15814449
54Taste transduction_Homo sapiens_hsa047421.12238845
55Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.10596500
56RNA degradation_Homo sapiens_hsa030181.09699110
57Glycerophospholipid metabolism_Homo sapiens_hsa005641.07924387
58Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.07781435
59Tight junction_Homo sapiens_hsa045301.05623048
60Cell cycle_Homo sapiens_hsa041101.04760939
61Phototransduction_Homo sapiens_hsa047441.03464147
62Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.03309431
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.02144790
64Dorso-ventral axis formation_Homo sapiens_hsa043201.00388874
65Peroxisome_Homo sapiens_hsa041460.98644986
66Lysosome_Homo sapiens_hsa041420.96822955
67Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.95667186
68Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.94365309
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.92754458
70Long-term potentiation_Homo sapiens_hsa047200.92410437
71Epstein-Barr virus infection_Homo sapiens_hsa051690.91971286
72Vibrio cholerae infection_Homo sapiens_hsa051100.91943498
73Circadian entrainment_Homo sapiens_hsa047130.91642042
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90647034
75Morphine addiction_Homo sapiens_hsa050320.89357462
76Pyruvate metabolism_Homo sapiens_hsa006200.87554880
77Hedgehog signaling pathway_Homo sapiens_hsa043400.84423565
78Carbohydrate digestion and absorption_Homo sapiens_hsa049730.83718001
79Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82640139
80Base excision repair_Homo sapiens_hsa034100.82109627
81Alcoholism_Homo sapiens_hsa050340.80406906
82Dopaminergic synapse_Homo sapiens_hsa047280.80029613
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.77129152
84Glycerolipid metabolism_Homo sapiens_hsa005610.76282528
85Arachidonic acid metabolism_Homo sapiens_hsa005900.73906029
86Ether lipid metabolism_Homo sapiens_hsa005650.73588937
87Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73385378
88Glucagon signaling pathway_Homo sapiens_hsa049220.73330717
89Serotonergic synapse_Homo sapiens_hsa047260.72492761
90Renin secretion_Homo sapiens_hsa049240.72063272
91Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.71446369
92Linoleic acid metabolism_Homo sapiens_hsa005910.70531490
93Calcium signaling pathway_Homo sapiens_hsa040200.69755826
94Biosynthesis of amino acids_Homo sapiens_hsa012300.67266905
95Salivary secretion_Homo sapiens_hsa049700.67265965
96Adherens junction_Homo sapiens_hsa045200.66806584
97Metabolic pathways_Homo sapiens_hsa011000.64546993
98Arginine and proline metabolism_Homo sapiens_hsa003300.63170361
99Fatty acid biosynthesis_Homo sapiens_hsa000610.62354221
100Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.62199299
101Cyanoamino acid metabolism_Homo sapiens_hsa004600.61960608
102Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61630282
103Insulin secretion_Homo sapiens_hsa049110.59191299
104Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58030207
105Wnt signaling pathway_Homo sapiens_hsa043100.57528148
106Gastric acid secretion_Homo sapiens_hsa049710.54430821
107Fructose and mannose metabolism_Homo sapiens_hsa000510.52407437
108Mineral absorption_Homo sapiens_hsa049780.51182555
109Systemic lupus erythematosus_Homo sapiens_hsa053220.50522013
110Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.50114787
111Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.49527775
112Long-term depression_Homo sapiens_hsa047300.49208520
113Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48206364
114Glutathione metabolism_Homo sapiens_hsa004800.47710039
115Renal cell carcinoma_Homo sapiens_hsa052110.46730833
116Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46168217
117Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44843637
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.41365491
119Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.41300641
120Carbon metabolism_Homo sapiens_hsa012000.41276856
121Oxytocin signaling pathway_Homo sapiens_hsa049210.41131574
122Butanoate metabolism_Homo sapiens_hsa006500.40195252
123Estrogen signaling pathway_Homo sapiens_hsa049150.39813925
124Folate biosynthesis_Homo sapiens_hsa007900.39774997
125Rheumatoid arthritis_Homo sapiens_hsa053230.38871968
126Allograft rejection_Homo sapiens_hsa053300.38833078
127alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38339790
128Phosphatidylinositol signaling system_Homo sapiens_hsa040700.37167412
129Cholinergic synapse_Homo sapiens_hsa047250.37087023
130Vitamin digestion and absorption_Homo sapiens_hsa049770.36646591
131Autoimmune thyroid disease_Homo sapiens_hsa053200.35702170
132Axon guidance_Homo sapiens_hsa043600.34914045
133Type I diabetes mellitus_Homo sapiens_hsa049400.34858539
134Fatty acid elongation_Homo sapiens_hsa000620.33801905
135Choline metabolism in cancer_Homo sapiens_hsa052310.33407855
136Gap junction_Homo sapiens_hsa045400.32817404
137Antigen processing and presentation_Homo sapiens_hsa046120.31729308
138Protein export_Homo sapiens_hsa030600.31513892
139Vascular smooth muscle contraction_Homo sapiens_hsa042700.31408164
140Melanogenesis_Homo sapiens_hsa049160.30591317
141Hematopoietic cell lineage_Homo sapiens_hsa046400.30483126
142cGMP-PKG signaling pathway_Homo sapiens_hsa040220.30330734
143Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.29410956
144Renin-angiotensin system_Homo sapiens_hsa046140.29233041
145Phagosome_Homo sapiens_hsa041450.28670852
146Circadian rhythm_Homo sapiens_hsa047100.28548734
147Graft-versus-host disease_Homo sapiens_hsa053320.27391436
148Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.27381907
149PPAR signaling pathway_Homo sapiens_hsa033200.26807026
150Regulation of autophagy_Homo sapiens_hsa041400.25510883
151Notch signaling pathway_Homo sapiens_hsa043300.23293396
152Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.21958497
153Complement and coagulation cascades_Homo sapiens_hsa046100.21730057
154Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18929742
155Endocytosis_Homo sapiens_hsa041440.18278337
156Jak-STAT signaling pathway_Homo sapiens_hsa046300.17484253
157Inositol phosphate metabolism_Homo sapiens_hsa005620.15458508
158Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.15389226
159RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.14964465
160Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.13995477
161Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.13288807
162cAMP signaling pathway_Homo sapiens_hsa040240.13128688
163Hepatitis C_Homo sapiens_hsa051600.12853524
164Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.12476979
165Prostate cancer_Homo sapiens_hsa052150.10567469
166Sulfur metabolism_Homo sapiens_hsa009200.08948113
167Sulfur relay system_Homo sapiens_hsa041220.05610052

Most similar genes based on co-expression Upload to Enrichr

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