SPC24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1telomere maintenance via semi-conservative replication (GO:0032201)5.32226512
2DNA strand elongation involved in DNA replication (GO:0006271)5.19386790
3DNA deamination (GO:0045006)5.12425219
4DNA strand elongation (GO:0022616)4.96755839
5ribosomal small subunit assembly (GO:0000028)4.92604348
6CENP-A containing nucleosome assembly (GO:0034080)4.86112620
7telomere maintenance via recombination (GO:0000722)4.77250620
8chromatin remodeling at centromere (GO:0031055)4.75657791
9DNA replication initiation (GO:0006270)4.69674123
10kinetochore organization (GO:0051383)4.64160749
11DNA replication checkpoint (GO:0000076)4.63230196
12mitotic recombination (GO:0006312)4.53772433
13kinetochore assembly (GO:0051382)4.47061703
14protein localization to kinetochore (GO:0034501)4.43890558
15mitotic metaphase plate congression (GO:0007080)4.38129602
16maturation of SSU-rRNA (GO:0030490)4.31237434
17telomere maintenance via telomere lengthening (GO:0010833)4.24511581
18DNA replication-independent nucleosome organization (GO:0034724)4.19390972
19DNA replication-independent nucleosome assembly (GO:0006336)4.19390972
20regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.17865503
21deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.17035806
22replication fork processing (GO:0031297)4.03711237
23DNA ligation (GO:0006266)4.02598571
24ribosomal small subunit biogenesis (GO:0042274)4.01220505
25DNA unwinding involved in DNA replication (GO:0006268)3.99626401
26nucleotide-excision repair, DNA gap filling (GO:0006297)3.99093768
27viral transcription (GO:0019083)3.97598319
28protein localization to chromosome, centromeric region (GO:0071459)3.93535118
29translational termination (GO:0006415)3.89619146
30ribosomal large subunit biogenesis (GO:0042273)3.88959417
31metaphase plate congression (GO:0051310)3.86058574
32regulation of nuclear cell cycle DNA replication (GO:0033262)3.82355531
33histone exchange (GO:0043486)3.82193188
34microtubule depolymerization (GO:0007019)3.80261646
35regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.77884729
36nucleobase biosynthetic process (GO:0046112)3.77607912
37proteasome assembly (GO:0043248)3.69702364
38attachment of spindle microtubules to kinetochore (GO:0008608)3.67586617
39DNA double-strand break processing (GO:0000729)3.64145186
40DNA replication-dependent nucleosome assembly (GO:0006335)3.63026855
41DNA replication-dependent nucleosome organization (GO:0034723)3.63026855
42establishment of chromosome localization (GO:0051303)3.61333092
43ribonucleoprotein complex biogenesis (GO:0022613)3.60304062
44purine nucleobase biosynthetic process (GO:0009113)3.59508867
45mitotic sister chromatid segregation (GO:0000070)3.57779680
46translational elongation (GO:0006414)3.53812208
47DNA topological change (GO:0006265)3.53288162
48regulation of double-strand break repair via homologous recombination (GO:0010569)3.53049294
49spliceosomal snRNP assembly (GO:0000387)3.51848475
50establishment of protein localization to mitochondrial membrane (GO:0090151)3.49210433
51chromosome segregation (GO:0007059)3.48324885
52formation of translation preinitiation complex (GO:0001731)3.46434370
53transcription-coupled nucleotide-excision repair (GO:0006283)3.39248283
54ribosome biogenesis (GO:0042254)3.38962797
55regulation of centriole replication (GO:0046599)3.38893275
56SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.38263699
57translational initiation (GO:0006413)3.37447300
58meiotic chromosome segregation (GO:0045132)3.37205302
59deoxyribonucleotide biosynthetic process (GO:0009263)3.34266292
60pseudouridine synthesis (GO:0001522)3.33408970
61rRNA processing (GO:0006364)3.32348481
62mitotic nuclear envelope disassembly (GO:0007077)3.32208542
63rRNA modification (GO:0000154)3.28904976
64cotranslational protein targeting to membrane (GO:0006613)3.28899944
65mitotic chromosome condensation (GO:0007076)3.28482291
66recombinational repair (GO:0000725)3.26838328
67regulation of centrosome cycle (GO:0046605)3.26298170
68protein targeting to ER (GO:0045047)3.26252269
69resolution of meiotic recombination intermediates (GO:0000712)3.25188746
70regulation of chromosome segregation (GO:0051983)3.25149662
71IMP biosynthetic process (GO:0006188)3.24350035
72DNA strand renaturation (GO:0000733)3.23848251
73nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.23708842
74regulation of mitochondrial translation (GO:0070129)3.22174125
75telomere maintenance (GO:0000723)3.21669860
76double-strand break repair via homologous recombination (GO:0000724)3.21380865
77telomere organization (GO:0032200)3.20912049
78rRNA metabolic process (GO:0016072)3.20161256
79regulation of DNA endoreduplication (GO:0032875)3.19792918
80anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.19707056
81spliceosomal complex assembly (GO:0000245)3.16355478
82negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.15064785
83sister chromatid segregation (GO:0000819)3.14434861
84translesion synthesis (GO:0019985)3.13866852
85DNA catabolic process, exonucleolytic (GO:0000738)3.13374281
86mismatch repair (GO:0006298)3.13170885
87mitotic spindle checkpoint (GO:0071174)3.12916076
88spindle checkpoint (GO:0031577)3.11958991
89postreplication repair (GO:0006301)3.11297524
90viral mRNA export from host cell nucleus (GO:0046784)3.10877412
91regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.10329331
92cellular protein complex disassembly (GO:0043624)3.09076170
93exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.08188829
94mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.08082296
95regulation of spindle organization (GO:0090224)3.07302322
96negative regulation of chromosome segregation (GO:0051985)3.07168562
97protein localization to endoplasmic reticulum (GO:0070972)3.06883036
98negative regulation of mitotic sister chromatid separation (GO:2000816)3.06585554
99negative regulation of mitotic sister chromatid segregation (GO:0033048)3.06585554
100negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.06585554
101negative regulation of sister chromatid segregation (GO:0033046)3.06585554
102establishment of protein localization to endoplasmic reticulum (GO:0072599)3.06534887
103nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.02323245
104viral life cycle (GO:0019058)3.02214607
105protein K6-linked ubiquitination (GO:0085020)3.01566553
106cell cycle G1/S phase transition (GO:0044843)3.01020688
107G1/S transition of mitotic cell cycle (GO:0000082)3.01020688
108maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.01006421
109positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.00531832
110spindle assembly checkpoint (GO:0071173)3.00409189
111protein localization to chromosome (GO:0034502)3.00148024
112establishment of integrated proviral latency (GO:0075713)2.99871895
113translation (GO:0006412)2.99796257
114mitotic spindle assembly checkpoint (GO:0007094)2.99696656
115chromatin assembly or disassembly (GO:0006333)2.99570967
116nuclear envelope disassembly (GO:0051081)2.99517930
117membrane disassembly (GO:0030397)2.99517930
118somatic hypermutation of immunoglobulin genes (GO:0016446)2.99411590
119somatic diversification of immune receptors via somatic mutation (GO:0002566)2.99411590
120negative regulation of DNA-dependent DNA replication (GO:2000104)2.99356872
121folic acid-containing compound biosynthetic process (GO:0009396)2.99259943
122ribosome assembly (GO:0042255)2.98604628
123transcription elongation from RNA polymerase III promoter (GO:0006385)2.98399148
124termination of RNA polymerase III transcription (GO:0006386)2.98399148
125mitochondrial respiratory chain complex assembly (GO:0033108)2.97809189
126negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.97698986
127* mitotic cell cycle (GO:0000278)2.97224411
128regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.94487961
129regulation of mitotic metaphase/anaphase transition (GO:0030071)2.94474431
130regulation of sister chromatid segregation (GO:0033045)2.93702311
131regulation of mitotic sister chromatid separation (GO:0010965)2.93702311
132regulation of mitotic sister chromatid segregation (GO:0033047)2.93702311
133protein complex biogenesis (GO:0070271)2.92603837
134regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.92352230
135regulation of mitotic spindle checkpoint (GO:1903504)2.92352230
136base-excision repair (GO:0006284)2.89334365
137synapsis (GO:0007129)2.87860362
138non-recombinational repair (GO:0000726)2.87506987
139double-strand break repair via nonhomologous end joining (GO:0006303)2.87506987

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.01424205
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.46991115
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.30579638
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.03389589
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.69859733
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.56983670
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.50951284
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.15205098
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.00670864
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.96031189
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.93102894
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.92533958
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.87457369
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.84208698
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.65722969
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.64930339
17FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.49548870
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.48901112
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.35515507
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.34974782
21XRN2_22483619_ChIP-Seq_HELA_Human2.28856011
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.28766591
23VDR_23849224_ChIP-Seq_CD4+_Human2.25139460
24MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.15603872
25MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.15178588
26* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.08812720
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.08402150
28HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.03366920
29FOXP3_21729870_ChIP-Seq_TREG_Human2.01941652
30E2F1_21310950_ChIP-Seq_MCF-7_Human2.00966139
31DCP1A_22483619_ChIP-Seq_HELA_Human2.00843456
32AR_21909140_ChIP-Seq_LNCAP_Human1.98973394
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.90082687
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.88552111
35TTF2_22483619_ChIP-Seq_HELA_Human1.86091422
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.83701242
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.79996567
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.79729781
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.79095807
40GABP_19822575_ChIP-Seq_HepG2_Human1.77100077
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.72500667
42SALL1_21062744_ChIP-ChIP_HESCs_Human1.71688660
43ELK1_19687146_ChIP-ChIP_HELA_Human1.68141336
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.66418443
45E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65574734
46SRF_21415370_ChIP-Seq_HL-1_Mouse1.63164459
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.61920146
48FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.59684045
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.59656502
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.57622851
51ZNF274_21170338_ChIP-Seq_K562_Hela1.57524246
52CIITA_25753668_ChIP-Seq_RAJI_Human1.55017273
53HOXB4_20404135_ChIP-ChIP_EML_Mouse1.52658367
54* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49574147
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.47575664
56HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.45293666
57FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39496508
58EWS_26573619_Chip-Seq_HEK293_Human1.38353057
59TP63_19390658_ChIP-ChIP_HaCaT_Human1.37489612
60KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.36475233
61ZFX_18555785_ChIP-Seq_MESCs_Mouse1.33332392
62VDR_22108803_ChIP-Seq_LS180_Human1.32024563
63SOX2_18555785_ChIP-Seq_MESCs_Mouse1.26401758
64SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26283345
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25291953
66KDM5A_27292631_Chip-Seq_BREAST_Human1.23508314
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.19827364
68EGR1_19374776_ChIP-ChIP_THP-1_Human1.15208260
69NOTCH1_21737748_ChIP-Seq_TLL_Human1.14922534
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.14844671
71* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.14692273
72POU5F1_16153702_ChIP-ChIP_HESCs_Human1.13517735
73PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.13132206
74SOX2_16153702_ChIP-ChIP_HESCs_Human1.12802144
75SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.12357131
76E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11567268
77* STAT3_1855785_ChIP-Seq_MESCs_Mouse1.09360575
78* MYC_18940864_ChIP-ChIP_HL60_Human1.07373722
79PADI4_21655091_ChIP-ChIP_MCF-7_Human1.07337836
80ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06604993
81POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05893320
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97150839
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.95409307
84MYC_22102868_ChIP-Seq_BL_Human0.94500421
85KLF4_18555785_ChIP-Seq_MESCs_Mouse0.94352370
86NANOG_16153702_ChIP-ChIP_HESCs_Human0.92617670
87BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.92511449
88DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91647711
89SPI1_23547873_ChIP-Seq_NB4_Human0.91518362
90FUS_26573619_Chip-Seq_HEK293_Human0.88599676
91GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.88242162
92CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.87899007
93KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87565031
94TFEB_21752829_ChIP-Seq_HELA_Human0.86389958
95CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.84697940
96ELK1_22589737_ChIP-Seq_MCF10A_Human0.84433287
97HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.83367506
98NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.82198845
99ESR1_15608294_ChIP-ChIP_MCF-7_Human0.81043388
100TCF3_18692474_ChIP-Seq_MEFs_Mouse0.80302829
101VDR_21846776_ChIP-Seq_THP-1_Human0.79192087
102CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.78152940
103SOX2_18692474_ChIP-Seq_MEFs_Mouse0.77698531
104TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.77534622
105IRF1_19129219_ChIP-ChIP_H3396_Human0.77237145
106IGF1R_20145208_ChIP-Seq_DFB_Human0.76806415
107RBPJ_22232070_ChIP-Seq_NCS_Mouse0.75214074
108* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.75106465
109CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74442938
110OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73574992
111MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.72042680
112CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.71213244
113IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.70539892
114KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.69079932
115KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.69079932
116TP53_22573176_ChIP-Seq_HFKS_Human0.66784492
117SOX17_20123909_ChIP-Seq_XEN_Mouse0.66439520
118HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.64413749
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.63836106
120PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.62259126
121SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.60984158
122FOXP1_21924763_ChIP-Seq_HESCs_Human0.60275531
123NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.58210643
124SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.57680391

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.84973174
2MP0010094_abnormal_chromosome_stability4.94929201
3MP0003111_abnormal_nucleus_morphology4.93942521
4MP0008057_abnormal_DNA_replication4.43414203
5MP0004957_abnormal_blastocyst_morpholog4.35461271
6MP0003077_abnormal_cell_cycle4.17249525
7MP0008058_abnormal_DNA_repair3.84475079
8MP0008007_abnormal_cellular_replicative3.10192204
9MP0008932_abnormal_embryonic_tissue2.71743971
10MP0000372_irregular_coat_pigmentation2.61854713
11MP0002396_abnormal_hematopoietic_system2.27093437
12MP0003786_premature_aging2.21537834
13MP0006292_abnormal_olfactory_placode2.05251712
14MP0000490_abnormal_crypts_of1.97853894
15MP0008877_abnormal_DNA_methylation1.95735787
16MP0000350_abnormal_cell_proliferation1.92286989
17MP0003718_maternal_effect1.90984483
18MP0001730_embryonic_growth_arrest1.75569319
19MP0005171_absent_coat_pigmentation1.73341195
20MP0003123_paternal_imprinting1.69579288
21MP0006072_abnormal_retinal_apoptosis1.55832281
22MP0009379_abnormal_foot_pigmentation1.52819213
23MP0002132_abnormal_respiratory_system1.49637959
24MP0000313_abnormal_cell_death1.48586820
25MP0002234_abnormal_pharynx_morphology1.47402493
26MP0003806_abnormal_nucleotide_metabolis1.46392568
27MP0002019_abnormal_tumor_incidence1.43329250
28MP0005380_embryogenesis_phenotype1.40443226
29MP0001672_abnormal_embryogenesis/_devel1.40443226
30MP0003186_abnormal_redox_activity1.39433871
31MP0001529_abnormal_vocalization1.37825153
32MP0003941_abnormal_skin_development1.37435541
33MP0001697_abnormal_embryo_size1.36419182
34MP0010307_abnormal_tumor_latency1.35933838
35MP0003315_abnormal_perineum_morphology1.34645757
36MP0010030_abnormal_orbit_morphology1.29328262
37MP0002080_prenatal_lethality1.28661726
38MP0004808_abnormal_hematopoietic_stem1.24803993
39MP0009333_abnormal_splenocyte_physiolog1.24225760
40MP0005075_abnormal_melanosome_morpholog1.23773024
41MP0003763_abnormal_thymus_physiology1.23725994
42MP0002163_abnormal_gland_morphology1.23271535
43MP0002210_abnormal_sex_determination1.22348748
44MP0000566_synostosis1.21826449
45MP0002085_abnormal_embryonic_tissue1.21229140
46MP0004133_heterotaxia1.19156773
47MP0008789_abnormal_olfactory_epithelium1.16892915
48MP0010352_gastrointestinal_tract_polyps1.16429918
49MP0003567_abnormal_fetal_cardiomyocyte1.15888733
50MP0003984_embryonic_growth_retardation1.15680754
51MP0000631_abnormal_neuroendocrine_gland1.14127248
52MP0002088_abnormal_embryonic_growth/wei1.11891813
53MP0000703_abnormal_thymus_morphology1.08253549
54MP0001293_anophthalmia1.08228474
55MP0005253_abnormal_eye_physiology1.07967454
56MP0003136_yellow_coat_color1.07100863
57MP0002160_abnormal_reproductive_system1.05198595
58MP0002398_abnormal_bone_marrow1.05191895
59MP0005408_hypopigmentation1.04452759
60MP0001145_abnormal_male_reproductive1.04006629
61MP0002086_abnormal_extraembryonic_tissu1.03241556
62MP0002722_abnormal_immune_system1.02094797
63MP0001853_heart_inflammation1.01089141
64MP0001545_abnormal_hematopoietic_system0.99975234
65MP0005397_hematopoietic_system_phenotyp0.99975234
66MP0001119_abnormal_female_reproductive0.99688155
67MP0005551_abnormal_eye_electrophysiolog0.98899683
68MP0005389_reproductive_system_phenotype0.97387114
69MP0000858_altered_metastatic_potential0.97275540
70MP0000689_abnormal_spleen_morphology0.96996243
71MP0005174_abnormal_tail_pigmentation0.95318525
72MP0003698_abnormal_male_reproductive0.95168557
73MP0003890_abnormal_embryonic-extraembry0.92025433
74MP0003646_muscle_fatigue0.90952158
75MP0001929_abnormal_gametogenesis0.89767900
76MP0001346_abnormal_lacrimal_gland0.89589154
77MP0000653_abnormal_sex_gland0.89481621
78MP0000427_abnormal_hair_cycle0.89358997
79MP0002084_abnormal_developmental_patter0.89341249
80MP0004197_abnormal_fetal_growth/weight/0.88652913
81MP0002429_abnormal_blood_cell0.85992054
82MP0002095_abnormal_skin_pigmentation0.85679003
83MP0005645_abnormal_hypothalamus_physiol0.85423082
84MP0000647_abnormal_sebaceous_gland0.84066548
85MP0001835_abnormal_antigen_presentation0.83958506
86MP0003121_genomic_imprinting0.83877902
87MP0001324_abnormal_eye_pigmentation0.83417083
88MP0005391_vision/eye_phenotype0.81681095
89MP0002638_abnormal_pupillary_reflex0.80826298
90MP0001919_abnormal_reproductive_system0.79459926
91MP0002111_abnormal_tail_morphology0.77101765
92MP0002751_abnormal_autonomic_nervous0.76173296
93MP0008872_abnormal_physiological_respon0.75532402
94MP0002736_abnormal_nociception_after0.75481049
95MP0001986_abnormal_taste_sensitivity0.73886510
96MP0006036_abnormal_mitochondrial_physio0.73804093
97MP0000716_abnormal_immune_system0.73031755
98MP0001485_abnormal_pinna_reflex0.72260236
99MP0000049_abnormal_middle_ear0.70445077
100MP0005084_abnormal_gallbladder_morpholo0.70421205
101MP0002938_white_spotting0.70297866
102MP0002697_abnormal_eye_size0.70106540
103MP0009697_abnormal_copulation0.69672366
104MP0005395_other_phenotype0.69319670
105MP0002277_abnormal_respiratory_mucosa0.68443166
106MP0003950_abnormal_plasma_membrane0.68384414
107MP0000015_abnormal_ear_pigmentation0.68080222
108MP0001764_abnormal_homeostasis0.67340368
109MP0003755_abnormal_palate_morphology0.66936504
110MP0003195_calcinosis0.66824838
111MP0001286_abnormal_eye_development0.66705795
112MP0006054_spinal_hemorrhage0.66124954
113MP0002161_abnormal_fertility/fecundity0.65617544
114MP0003861_abnormal_nervous_system0.65220991
115MP0002233_abnormal_nose_morphology0.65099743
116MP0005394_taste/olfaction_phenotype0.64903183
117MP0005499_abnormal_olfactory_system0.64903183
118MP0000678_abnormal_parathyroid_gland0.64702739
119MP0005646_abnormal_pituitary_gland0.64164852
120MP0008995_early_reproductive_senescence0.63253775
121MP0000358_abnormal_cell_content/0.63231565
122MP0001188_hyperpigmentation0.62772445
123MP0006035_abnormal_mitochondrial_morpho0.62744561
124MP0003119_abnormal_digestive_system0.62592194
125MP0004147_increased_porphyrin_level0.62127943
126MP0002075_abnormal_coat/hair_pigmentati0.61382682
127MP0005384_cellular_phenotype0.61011748
128MP0001186_pigmentation_phenotype0.60511971
129MP0002102_abnormal_ear_morphology0.60278886
130MP0002420_abnormal_adaptive_immunity0.58308024
131MP0001819_abnormal_immune_cell0.58206096
132MP0001800_abnormal_humoral_immune0.58152673
133MP0000477_abnormal_intestine_morphology0.56412364
134MP0002452_abnormal_antigen_presenting0.56152645
135MP0005671_abnormal_response_to0.54797875
136MP0003937_abnormal_limbs/digits/tail_de0.54501821

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.15929375
2Chromosomal breakage induced by crosslinking agents (HP:0003221)5.00551733
3Chromsome breakage (HP:0040012)4.91144276
4Birth length less than 3rd percentile (HP:0003561)4.91106632
5Abnormality of cells of the erythroid lineage (HP:0012130)4.28619270
6Abnormal number of erythroid precursors (HP:0012131)4.24410223
7Breast hypoplasia (HP:0003187)4.04587818
8Meckel diverticulum (HP:0002245)3.74070732
9Oral leukoplakia (HP:0002745)3.65503781
10Abnormality of the preputium (HP:0100587)3.61693299
11Abnormality of the ileum (HP:0001549)3.57482470
12Abnormality of chromosome stability (HP:0003220)3.41595255
13Duplicated collecting system (HP:0000081)3.36529482
14Aplastic anemia (HP:0001915)3.33857812
15Aplasia/Hypoplasia of the uvula (HP:0010293)3.31779420
16Patellar aplasia (HP:0006443)3.31239825
17Abnormality of the renal collecting system (HP:0004742)3.17633663
18Acute necrotizing encephalopathy (HP:0006965)3.15612316
19Macrocytic anemia (HP:0001972)3.12105045
20Aplasia/Hypoplasia of the patella (HP:0006498)3.12001157
21Pallor (HP:0000980)3.11017244
22Carpal bone hypoplasia (HP:0001498)3.08982278
23Aplasia/Hypoplasia of the sacrum (HP:0008517)3.04121713
24Absent thumb (HP:0009777)3.01476768
25Colon cancer (HP:0003003)3.00099847
26Abnormal mitochondria in muscle tissue (HP:0008316)2.94387606
27Acute encephalopathy (HP:0006846)2.92120651
28Increased CSF lactate (HP:0002490)2.90782261
29Mitochondrial inheritance (HP:0001427)2.90419012
30Rough bone trabeculation (HP:0100670)2.90144911
31Small intestinal stenosis (HP:0012848)2.89627372
32Duodenal stenosis (HP:0100867)2.89627372
3311 pairs of ribs (HP:0000878)2.82641185
34Absent radius (HP:0003974)2.79857628
35Bone marrow hypocellularity (HP:0005528)2.75727428
36Myelodysplasia (HP:0002863)2.74398696
37Selective tooth agenesis (HP:0001592)2.73860118
38Pancreatic cysts (HP:0001737)2.64845302
39Aplasia involving forearm bones (HP:0009822)2.62236994
40Absent forearm bone (HP:0003953)2.62236994
41Premature graying of hair (HP:0002216)2.61772451
42Impulsivity (HP:0100710)2.61376665
43Lipid accumulation in hepatocytes (HP:0006561)2.58551700
44Abnormality of the anterior horn cell (HP:0006802)2.58399026
45Degeneration of anterior horn cells (HP:0002398)2.58399026
46Triphalangeal thumb (HP:0001199)2.56720697
47Progressive macrocephaly (HP:0004481)2.56268758
48Abnormal lung lobation (HP:0002101)2.55386786
49Hepatocellular necrosis (HP:0001404)2.54361624
50Abnormality of pyrimidine metabolism (HP:0004353)2.53996404
51Medulloblastoma (HP:0002885)2.52716797
52Abnormality of the labia minora (HP:0012880)2.51800894
53Microretrognathia (HP:0000308)2.51164732
54Horseshoe kidney (HP:0000085)2.47982052
55Clubbing of toes (HP:0100760)2.47794198
56Molar tooth sign on MRI (HP:0002419)2.42498917
57Abnormality of midbrain morphology (HP:0002418)2.42498917
58Type I transferrin isoform profile (HP:0003642)2.41806553
59Abnormality of the duodenum (HP:0002246)2.40524693
60Pancreatic fibrosis (HP:0100732)2.39085343
61Sloping forehead (HP:0000340)2.38680832
62Pancytopenia (HP:0001876)2.35604266
63Tracheoesophageal fistula (HP:0002575)2.33859121
64Hypoplasia of the pons (HP:0012110)2.33086368
65Hepatic necrosis (HP:0002605)2.32106711
66Ectopic kidney (HP:0000086)2.32012681
67Abnormality of the pons (HP:0007361)2.28989391
68Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.27270736
69Microvesicular hepatic steatosis (HP:0001414)2.24241237
70Cleft eyelid (HP:0000625)2.24040643
71Neoplasm of the pancreas (HP:0002894)2.22739696
72Cellular immunodeficiency (HP:0005374)2.22081256
73True hermaphroditism (HP:0010459)2.20055735
74Cerebral edema (HP:0002181)2.19041315
75Supernumerary spleens (HP:0009799)2.18849094
76Cerebral hypomyelination (HP:0006808)2.18647834
77Agnosia (HP:0010524)2.18154885
78Abnormality of the carotid arteries (HP:0005344)2.15480376
79Abnormal trabecular bone morphology (HP:0100671)2.14318966
80Abnormality of DNA repair (HP:0003254)2.13891294
81Pendular nystagmus (HP:0012043)2.12950967
82Abnormal number of incisors (HP:0011064)2.12535643
83Sclerocornea (HP:0000647)2.11850606
84Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.11010081
85Decreased activity of mitochondrial respiratory chain (HP:0008972)2.11010081
86Abnormality of the heme biosynthetic pathway (HP:0010472)2.10272557
87Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.07364685
88Abnormality of alanine metabolism (HP:0010916)2.07364685
89Hyperalaninemia (HP:0003348)2.07364685
90Increased serum lactate (HP:0002151)2.06877340
91Nephroblastoma (Wilms tumor) (HP:0002667)2.04697441
92Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.04216364
93Cerebellar dysplasia (HP:0007033)2.03924892
94Volvulus (HP:0002580)2.02459851
95Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.00512334
96Short thumb (HP:0009778)2.00238521
97Type II lissencephaly (HP:0007260)1.99400532
98Lactic acidosis (HP:0003128)1.99033155
99Hypoplasia of the capital femoral epiphysis (HP:0003090)1.96885591
100Lymphoma (HP:0002665)1.95084657
101Rhabdomyosarcoma (HP:0002859)1.94573744
102Trismus (HP:0000211)1.94360172
103Premature ovarian failure (HP:0008209)1.93920418
104Squamous cell carcinoma (HP:0002860)1.90292814
105Renal Fanconi syndrome (HP:0001994)1.89504735
106Sparse eyelashes (HP:0000653)1.88771902
107Embryonal renal neoplasm (HP:0011794)1.88050256
108Abnormality of reticulocytes (HP:0004312)1.86185745
109Increased nuchal translucency (HP:0010880)1.85299676
110Asplenia (HP:0001746)1.84687856
1113-Methylglutaconic aciduria (HP:0003535)1.84023935
112Preaxial hand polydactyly (HP:0001177)1.81907120
113Hypoplasia of the radius (HP:0002984)1.81857454
114Nephronophthisis (HP:0000090)1.81410021
115Optic nerve coloboma (HP:0000588)1.80405269
116Hypoplastic pelvis (HP:0008839)1.79107816
117Secondary amenorrhea (HP:0000869)1.78569664
118Arteriovenous malformation (HP:0100026)1.77812706
119Atresia of the external auditory canal (HP:0000413)1.77705875
120Neoplasm of the colon (HP:0100273)1.77035504
121Small hand (HP:0200055)1.76752695
122Muscle fiber atrophy (HP:0100295)1.76163920
123Glioma (HP:0009733)1.75954812
124Oligohydramnios (HP:0001562)1.74445655
125Dandy-Walker malformation (HP:0001305)1.74233310
126Acute lymphatic leukemia (HP:0006721)1.74026222
127Thrombocytosis (HP:0001894)1.73926301
128Aplasia/Hypoplasia of the fovea (HP:0008060)1.73686416
129Hypoplasia of the fovea (HP:0007750)1.73686416
130Abdominal situs inversus (HP:0003363)1.73259493
131Abnormality of abdominal situs (HP:0011620)1.73259493
132Ureteral duplication (HP:0000073)1.72879952
133Abnormality of cochlea (HP:0000375)1.72541611
134Type 2 muscle fiber atrophy (HP:0003554)1.72386804
135Abnormality of glycolysis (HP:0004366)1.72275362
136Granulocytopenia (HP:0001913)1.72129690
137Exertional dyspnea (HP:0002875)1.71508610
138Neoplasm of the adrenal cortex (HP:0100641)1.70306676
139Ependymoma (HP:0002888)1.70014923
140High pitched voice (HP:0001620)1.69535146
141IgM deficiency (HP:0002850)1.69464255
142Poor head control (HP:0002421)1.68710007
143Methylmalonic aciduria (HP:0012120)1.68136360
144Megaloblastic anemia (HP:0001889)1.68009881
145Congenital stationary night blindness (HP:0007642)1.67940980
146Increased hepatocellular lipid droplets (HP:0006565)1.66668838
147Duplication of thumb phalanx (HP:0009942)1.66555087
148Abnormal protein glycosylation (HP:0012346)1.65967881
149Abnormal glycosylation (HP:0012345)1.65967881
150Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.65967881
151Abnormal protein N-linked glycosylation (HP:0012347)1.65967881
152Astigmatism (HP:0000483)1.65868825
153Lissencephaly (HP:0001339)1.64115724

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.02911238
2WEE14.30316299
3VRK23.77178464
4CDC73.73222928
5SRPK13.05149727
6EIF2AK12.95909676
7STK162.95333506
8PLK42.85982723
9VRK12.59616251
10TTK2.53831601
11TLK12.53408855
12NEK22.42151568
13ZAK2.35219243
14NME22.21792408
15PLK12.14919794
16BRSK22.14031556
17CCNB11.99788931
18EIF2AK31.93894513
19TAF11.88451888
20AURKB1.78717223
21MKNK11.78154116
22ATR1.73831306
23ACVR1B1.71504850
24BMPR1B1.71304528
25CDK71.69923746
26NEK11.64170637
27TSSK61.63413638
28IRAK31.55417032
29PLK31.48896431
30CHEK21.48135535
31MKNK21.46738661
32BRSK11.45986302
33STK41.44879007
34FRK1.43126812
35TESK21.41392436
36DYRK31.40681727
37EIF2AK21.34259248
38AURKA1.29837838
39IRAK41.27120979
40RPS6KB21.23979797
41RPS6KA41.23962964
42PBK1.20236732
43EPHA21.18529469
44WNK31.14406955
45MAP3K81.11500379
46PASK1.09505442
47CDK41.08749563
48TRIM281.03341512
49CHEK10.96755464
50MAP4K20.94634059
51PLK20.90150842
52PIM20.86057219
53PIM10.85756689
54CSNK1G30.83948647
55MAP3K110.79866829
56STK100.79135054
57MAPKAPK50.78719282
58CLK10.78144993
59KDR0.78102083
60CDK80.77847523
61ATM0.77514934
62MAP4K10.77357425
63PAK40.76660051
64CSNK2A10.76607190
65GRK10.74328576
66BRAF0.73848602
67INSRR0.71830767
68TEC0.71791409
69CSNK1A1L0.71342546
70CSNK1G10.69391115
71CDK20.69372721
72CDK120.68085602
73WNK40.66204950
74RPS6KA50.64976638
75MUSK0.64526969
76CSNK2A20.64173215
77YES10.63851293
78BRD40.63768709
79NME10.63713687
80MARK30.63191276
81MAPK130.62772038
82TNIK0.62103804
83PDK20.62082738
84CSNK1G20.58746459
85BLK0.58293455
86STK38L0.57531034
87FLT30.57347795
88CDK10.54136273
89BTK0.52707576
90TXK0.52310853
91PRKCI0.51684877
92BCKDK0.51258199
93SMG10.50120557
94STK30.49183800
95IKBKB0.48846361
96ERBB30.47748906
97PAK10.46970587
98TAOK20.46177335
99SCYL20.45543640
100NEK90.42192585
101CDK60.38517321
102DAPK10.38112217
103AKT30.37918686
104PKN10.36691041
105TGFBR10.36425576
106TESK10.36360006
107DYRK20.35576492
108MST40.35419020
109LYN0.34652230
110ABL20.33508963
111AKT20.33468765
112MELK0.32689126
113MAP3K40.30746991
114MAP2K70.30175897
115MAP2K30.25661824
116STK390.23690054
117PRKDC0.23224980
118MAPKAPK30.22768170
119PINK10.21960877
120CHUK0.20518076
121PNCK0.19808475
122OXSR10.19209189
123DAPK30.19154851
124CDK30.18842532
125NUAK10.18321412
126ADRBK10.18092029
127KIT0.17995856
128CSNK1E0.17845859
129AKT10.17703741
130LIMK10.17560367
131ADRBK20.16733126
132RPS6KA60.16366137
133RPS6KC10.16283263
134RPS6KL10.16283263
135MAP2K60.16038208

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.38020219
2Mismatch repair_Homo sapiens_hsa034304.59640022
3Ribosome_Homo sapiens_hsa030103.99315346
4Homologous recombination_Homo sapiens_hsa034403.49914579
5Base excision repair_Homo sapiens_hsa034103.41834763
6Proteasome_Homo sapiens_hsa030503.29422973
7RNA polymerase_Homo sapiens_hsa030203.20337317
8Spliceosome_Homo sapiens_hsa030403.18923830
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.16919073
10Nucleotide excision repair_Homo sapiens_hsa034202.90808385
11Fanconi anemia pathway_Homo sapiens_hsa034602.76096376
12Pyrimidine metabolism_Homo sapiens_hsa002402.75170174
13One carbon pool by folate_Homo sapiens_hsa006702.64028708
14RNA transport_Homo sapiens_hsa030132.59150889
15Cell cycle_Homo sapiens_hsa041102.50393100
16Non-homologous end-joining_Homo sapiens_hsa034502.09608582
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.05318098
18RNA degradation_Homo sapiens_hsa030181.81822248
19Basal transcription factors_Homo sapiens_hsa030221.71767071
20p53 signaling pathway_Homo sapiens_hsa041151.51772239
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.51285113
22Purine metabolism_Homo sapiens_hsa002301.46075696
23mRNA surveillance pathway_Homo sapiens_hsa030151.31387364
24Systemic lupus erythematosus_Homo sapiens_hsa053221.29767203
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.23368420
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.20642999
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.14668983
28Propanoate metabolism_Homo sapiens_hsa006401.09690998
29Folate biosynthesis_Homo sapiens_hsa007901.08621270
30Pyruvate metabolism_Homo sapiens_hsa006201.04350320
31Epstein-Barr virus infection_Homo sapiens_hsa051691.03399615
32Protein export_Homo sapiens_hsa030600.95718719
33Herpes simplex infection_Homo sapiens_hsa051680.91470586
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91062682
35Drug metabolism - other enzymes_Homo sapiens_hsa009830.89784884
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.89079459
37Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.88587574
38Huntingtons disease_Homo sapiens_hsa050160.88388142
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79226749
40Parkinsons disease_Homo sapiens_hsa050120.78288668
41Butanoate metabolism_Homo sapiens_hsa006500.78204481
42Fatty acid elongation_Homo sapiens_hsa000620.77936661
43Pentose phosphate pathway_Homo sapiens_hsa000300.74592303
44Steroid biosynthesis_Homo sapiens_hsa001000.73541613
45Cysteine and methionine metabolism_Homo sapiens_hsa002700.73342146
46Nitrogen metabolism_Homo sapiens_hsa009100.72314249
47Cyanoamino acid metabolism_Homo sapiens_hsa004600.71175701
48Glutathione metabolism_Homo sapiens_hsa004800.69759283
49Sulfur relay system_Homo sapiens_hsa041220.69612749
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.68675679
51Oxidative phosphorylation_Homo sapiens_hsa001900.66846516
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.66408710
53Phototransduction_Homo sapiens_hsa047440.66063324
54Viral carcinogenesis_Homo sapiens_hsa052030.65879127
55Antigen processing and presentation_Homo sapiens_hsa046120.65651735
562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.65023786
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64488883
58Primary immunodeficiency_Homo sapiens_hsa053400.64431698
59Oocyte meiosis_Homo sapiens_hsa041140.61327270
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60595164
61Selenocompound metabolism_Homo sapiens_hsa004500.60405728
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59062169
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57431450
64Cardiac muscle contraction_Homo sapiens_hsa042600.56976662
65HTLV-I infection_Homo sapiens_hsa051660.56234192
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54655119
67Lysine degradation_Homo sapiens_hsa003100.54276960
68Vitamin B6 metabolism_Homo sapiens_hsa007500.53603006
69Sulfur metabolism_Homo sapiens_hsa009200.52411244
70Biosynthesis of amino acids_Homo sapiens_hsa012300.52326263
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50544305
72Arachidonic acid metabolism_Homo sapiens_hsa005900.49504919
73Tryptophan metabolism_Homo sapiens_hsa003800.49072892
74Legionellosis_Homo sapiens_hsa051340.48941840
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47897764
76Peroxisome_Homo sapiens_hsa041460.46226734
77NF-kappa B signaling pathway_Homo sapiens_hsa040640.44452945
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.43033509
79Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42950045
80Measles_Homo sapiens_hsa051620.38168986
81Apoptosis_Homo sapiens_hsa042100.37867751
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37718045
83Transcriptional misregulation in cancer_Homo sapiens_hsa052020.37394157
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37359405
85Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.36617196
86Metabolic pathways_Homo sapiens_hsa011000.36385541
87RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.35234617
88Alcoholism_Homo sapiens_hsa050340.34163297
89Small cell lung cancer_Homo sapiens_hsa052220.33960656
90Fructose and mannose metabolism_Homo sapiens_hsa000510.33431344
91Hedgehog signaling pathway_Homo sapiens_hsa043400.33224320
92Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.32249566
93Intestinal immune network for IgA production_Homo sapiens_hsa046720.32055014
94Galactose metabolism_Homo sapiens_hsa000520.31889807
95Hematopoietic cell lineage_Homo sapiens_hsa046400.31300608
96Maturity onset diabetes of the young_Homo sapiens_hsa049500.31045179
97MicroRNAs in cancer_Homo sapiens_hsa052060.30632698
98Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30224149
99N-Glycan biosynthesis_Homo sapiens_hsa005100.29931747
100Fatty acid metabolism_Homo sapiens_hsa012120.29466334
101Thyroid cancer_Homo sapiens_hsa052160.28246398
102Carbon metabolism_Homo sapiens_hsa012000.25297595
103Allograft rejection_Homo sapiens_hsa053300.25061168
104Alzheimers disease_Homo sapiens_hsa050100.23682168
105Ether lipid metabolism_Homo sapiens_hsa005650.23508867
106NOD-like receptor signaling pathway_Homo sapiens_hsa046210.22757100
107Basal cell carcinoma_Homo sapiens_hsa052170.22473266
108Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.21774097
109Hepatitis B_Homo sapiens_hsa051610.20039358
110Caffeine metabolism_Homo sapiens_hsa002320.19204496
111Graft-versus-host disease_Homo sapiens_hsa053320.18777626
112Influenza A_Homo sapiens_hsa051640.18054836
113Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.17948313
114Notch signaling pathway_Homo sapiens_hsa043300.17419766
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.17029759
116Other glycan degradation_Homo sapiens_hsa005110.15642240
117Olfactory transduction_Homo sapiens_hsa047400.14974836
118beta-Alanine metabolism_Homo sapiens_hsa004100.14901324
119Arginine and proline metabolism_Homo sapiens_hsa003300.14828070
120Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.14749691
121Asthma_Homo sapiens_hsa053100.14665772
122Linoleic acid metabolism_Homo sapiens_hsa005910.14541921
123Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.13598271
124Shigellosis_Homo sapiens_hsa051310.12210277
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.12050848
126Autoimmune thyroid disease_Homo sapiens_hsa053200.11251723
127Fatty acid degradation_Homo sapiens_hsa000710.09334312
128Steroid hormone biosynthesis_Homo sapiens_hsa001400.09137912
129Vitamin digestion and absorption_Homo sapiens_hsa049770.09050495
130TGF-beta signaling pathway_Homo sapiens_hsa043500.08721446
131Pathways in cancer_Homo sapiens_hsa052000.07698756
132Renin-angiotensin system_Homo sapiens_hsa046140.07522509
133Hippo signaling pathway_Homo sapiens_hsa043900.06355260
134Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.06234162
135Bladder cancer_Homo sapiens_hsa052190.06063684
136Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.05961004
137Leishmaniasis_Homo sapiens_hsa051400.05710276

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »