

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.19028624 |
| 2 | signal peptide processing (GO:0006465) | 4.81656125 |
| 3 | proteasome assembly (GO:0043248) | 4.53984214 |
| 4 | respiratory chain complex IV assembly (GO:0008535) | 4.32269038 |
| 5 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.12551914 |
| 6 | cytochrome complex assembly (GO:0017004) | 3.93815751 |
| 7 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.91417305 |
| 8 | cytidine deamination (GO:0009972) | 3.90517515 |
| 9 | cytidine metabolic process (GO:0046087) | 3.90517515 |
| 10 | cytidine catabolic process (GO:0006216) | 3.90517515 |
| 11 | DNA double-strand break processing (GO:0000729) | 3.76160877 |
| 12 | lactate metabolic process (GO:0006089) | 3.71832148 |
| 13 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.70186422 |
| 14 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.70123050 |
| 15 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.63796017 |
| 16 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.63796017 |
| 17 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.63796017 |
| 18 | cullin deneddylation (GO:0010388) | 3.61648848 |
| 19 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.59448847 |
| 20 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.58386249 |
| 21 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.58386249 |
| 22 | protein complex biogenesis (GO:0070271) | 3.53328335 |
| 23 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.50457200 |
| 24 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.50457200 |
| 25 | isotype switching (GO:0045190) | 3.50457200 |
| 26 | mannosylation (GO:0097502) | 3.49445279 |
| 27 | protein deneddylation (GO:0000338) | 3.48220364 |
| 28 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.47270786 |
| 29 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.45303168 |
| 30 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.44767869 |
| 31 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.44767869 |
| 32 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.43634733 |
| 33 | rRNA modification (GO:0000154) | 3.43241841 |
| 34 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.37244089 |
| 35 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.34274290 |
| 36 | negative regulation of ligase activity (GO:0051352) | 3.34274290 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.31967968 |
| 38 | maturation of 5.8S rRNA (GO:0000460) | 3.30503299 |
| 39 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.28268871 |
| 40 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.28147869 |
| 41 | fucose catabolic process (GO:0019317) | 3.26129474 |
| 42 | L-fucose metabolic process (GO:0042354) | 3.26129474 |
| 43 | L-fucose catabolic process (GO:0042355) | 3.26129474 |
| 44 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.23668297 |
| 45 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.23064482 |
| 46 | platelet dense granule organization (GO:0060155) | 3.22000034 |
| 47 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.18162312 |
| 48 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.18162312 |
| 49 | pseudouridine synthesis (GO:0001522) | 3.17721785 |
| 50 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.16626859 |
| 51 | ATP synthesis coupled proton transport (GO:0015986) | 3.16626859 |
| 52 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.11746864 |
| 53 | branched-chain amino acid catabolic process (GO:0009083) | 3.09204508 |
| 54 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.08559859 |
| 55 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.07218168 |
| 56 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.06106210 |
| 57 | protein-cofactor linkage (GO:0018065) | 3.05819128 |
| 58 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.04984556 |
| 59 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.01928905 |
| 60 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.00807091 |
| 61 | termination of RNA polymerase III transcription (GO:0006386) | 3.00807091 |
| 62 | positive regulation of ligase activity (GO:0051351) | 2.97683758 |
| 63 | protein neddylation (GO:0045116) | 2.95395920 |
| 64 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.91273371 |
| 65 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.88549303 |
| 66 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.88549303 |
| 67 | NADH dehydrogenase complex assembly (GO:0010257) | 2.88549303 |
| 68 | rRNA methylation (GO:0031167) | 2.84730718 |
| 69 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.84245945 |
| 70 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.81804838 |
| 71 | regulation of cellular amine metabolic process (GO:0033238) | 2.81174812 |
| 72 | electron transport chain (GO:0022900) | 2.80324255 |
| 73 | respiratory electron transport chain (GO:0022904) | 2.80194097 |
| 74 | positive regulation of cell cycle arrest (GO:0071158) | 2.75639514 |
| 75 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.75122128 |
| 76 | regulation of mitochondrial translation (GO:0070129) | 2.72111136 |
| 77 | adenosine metabolic process (GO:0046085) | 2.71330617 |
| 78 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.66257219 |
| 79 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.65981538 |
| 80 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.63859303 |
| 81 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.63859303 |
| 82 | C-terminal protein lipidation (GO:0006501) | 2.60083441 |
| 83 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.56737992 |
| 84 | regulation of hexokinase activity (GO:1903299) | 2.55304232 |
| 85 | regulation of glucokinase activity (GO:0033131) | 2.55304232 |
| 86 | somatic diversification of immunoglobulins (GO:0016445) | 2.54998543 |
| 87 | cellular ketone body metabolic process (GO:0046950) | 2.53793820 |
| 88 | regulation of ligase activity (GO:0051340) | 2.52783415 |
| 89 | tRNA processing (GO:0008033) | 2.52672797 |
| 90 | negative regulation of telomere maintenance (GO:0032205) | 2.51918141 |
| 91 | S-adenosylmethionine metabolic process (GO:0046500) | 2.48868118 |
| 92 | dopamine transport (GO:0015872) | 2.48196737 |
| 93 | branched-chain amino acid metabolic process (GO:0009081) | 2.47245216 |
| 94 | histone H2A acetylation (GO:0043968) | 2.46727081 |
| 95 | nucleobase biosynthetic process (GO:0046112) | 2.46540704 |
| 96 | ubiquinone biosynthetic process (GO:0006744) | 2.45978429 |
| 97 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.45016556 |
| 98 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.44846692 |
| 99 | GPI anchor biosynthetic process (GO:0006506) | 2.44632438 |
| 100 | replication fork processing (GO:0031297) | 2.44327791 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.89373495 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.10140334 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.63467465 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.56329795 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.23132642 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.10570189 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.92526981 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.91076500 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.72441210 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.63781125 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.55204706 |
| 12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.46848438 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.38992056 |
| 14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.38714161 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.33560652 |
| 16 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.32620991 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.24066995 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.16671614 |
| 19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.08967014 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.07640321 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.97388488 |
| 22 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.96643410 |
| 23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.96325196 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.96039658 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.93729447 |
| 26 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.89856655 |
| 27 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.85895947 |
| 28 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.84703846 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.81512338 |
| 30 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.80166117 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.70705276 |
| 32 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.70673998 |
| 33 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.65889982 |
| 34 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.59350256 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56089693 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.55208879 |
| 37 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.53821809 |
| 38 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.52410644 |
| 39 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.47280431 |
| 40 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.46333786 |
| 41 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.46256943 |
| 42 | EWS_26573619_Chip-Seq_HEK293_Human | 1.40986211 |
| 43 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.40168690 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.37682346 |
| 45 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.37154879 |
| 46 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.36905668 |
| 47 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.33013965 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32466483 |
| 49 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.32053993 |
| 50 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.30325023 |
| 51 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.25236593 |
| 52 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.24866719 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.23719694 |
| 54 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.23719694 |
| 55 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.23001087 |
| 56 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.22818205 |
| 57 | AR_20517297_ChIP-Seq_VCAP_Human | 1.21660103 |
| 58 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20107289 |
| 59 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.19706374 |
| 60 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.18994664 |
| 61 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.16816709 |
| 62 | GATA3_26560356_Chip-Seq_TH2_Human | 1.14489851 |
| 63 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.13779467 |
| 64 | P300_19829295_ChIP-Seq_ESCs_Human | 1.12482272 |
| 65 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.11953203 |
| 66 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.11022476 |
| 67 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.10728450 |
| 68 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.10277143 |
| 69 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.09860316 |
| 70 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.08771019 |
| 71 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.08001754 |
| 72 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.07263811 |
| 73 | FUS_26573619_Chip-Seq_HEK293_Human | 1.06713876 |
| 74 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.06481583 |
| 75 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06205602 |
| 76 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06205602 |
| 77 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.05571067 |
| 78 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.03066698 |
| 79 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.00729771 |
| 80 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00077269 |
| 81 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.99122844 |
| 82 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.96933828 |
| 83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.96587264 |
| 84 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95820477 |
| 85 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.94566558 |
| 86 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.93226801 |
| 87 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91873982 |
| 88 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91580101 |
| 89 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.91488124 |
| 90 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91430447 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.90975643 |
| 92 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.90733858 |
| 93 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.90616110 |
| 94 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.89764270 |
| 95 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.88829223 |
| 96 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.88598751 |
| 97 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.87647367 |
| 98 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.87314987 |
| 99 | NCOR_22424771_ChIP-Seq_293T_Human | 0.86803712 |
| 100 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.84339140 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003195_calcinosis | 3.35845065 |
| 2 | MP0005671_abnormal_response_to | 3.07254584 |
| 3 | MP0002837_dystrophic_cardiac_calcinosis | 2.89791341 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 2.79269749 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.74371721 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.71308309 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.54655374 |
| 8 | MP0008058_abnormal_DNA_repair | 2.45625066 |
| 9 | MP0002102_abnormal_ear_morphology | 2.34783631 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.30462564 |
| 11 | MP0003787_abnormal_imprinting | 2.25715683 |
| 12 | MP0003786_premature_aging | 2.23499830 |
| 13 | MP0002163_abnormal_gland_morphology | 2.18659618 |
| 14 | MP0009785_altered_susceptibility_to | 2.17207475 |
| 15 | MP0006036_abnormal_mitochondrial_physio | 2.05407266 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 1.96218949 |
| 17 | MP0002138_abnormal_hepatobiliary_system | 1.96013312 |
| 18 | MP0010094_abnormal_chromosome_stability | 1.90710792 |
| 19 | MP0008872_abnormal_physiological_respon | 1.87490662 |
| 20 | MP0005379_endocrine/exocrine_gland_phen | 1.83812409 |
| 21 | MP0002876_abnormal_thyroid_physiology | 1.74947457 |
| 22 | MP0002254_reproductive_system_inflammat | 1.73523017 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.71257915 |
| 24 | MP0002166_altered_tumor_susceptibility | 1.67898839 |
| 25 | MP0000685_abnormal_immune_system | 1.66309120 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.65588507 |
| 27 | MP0008875_abnormal_xenobiotic_pharmacok | 1.62965901 |
| 28 | MP0006035_abnormal_mitochondrial_morpho | 1.62965715 |
| 29 | MP0009697_abnormal_copulation | 1.61319132 |
| 30 | MP0002693_abnormal_pancreas_physiology | 1.58842837 |
| 31 | MP0000372_irregular_coat_pigmentation | 1.57813468 |
| 32 | MP0009333_abnormal_splenocyte_physiolog | 1.56967593 |
| 33 | MP0001873_stomach_inflammation | 1.53181282 |
| 34 | MP0003186_abnormal_redox_activity | 1.49710642 |
| 35 | MP0005387_immune_system_phenotype | 1.47278516 |
| 36 | MP0001790_abnormal_immune_system | 1.47278516 |
| 37 | MP0005253_abnormal_eye_physiology | 1.42591942 |
| 38 | MP0005000_abnormal_immune_tolerance | 1.40112407 |
| 39 | MP0002006_tumorigenesis | 1.38452385 |
| 40 | MP0008007_abnormal_cellular_replicative | 1.36730590 |
| 41 | MP0001800_abnormal_humoral_immune | 1.34549381 |
| 42 | MP0003011_delayed_dark_adaptation | 1.33440859 |
| 43 | MP0005551_abnormal_eye_electrophysiolog | 1.32790814 |
| 44 | MP0003718_maternal_effect | 1.31367295 |
| 45 | MP0000516_abnormal_urinary_system | 1.30459120 |
| 46 | MP0005367_renal/urinary_system_phenotyp | 1.30459120 |
| 47 | MP0002139_abnormal_hepatobiliary_system | 1.26696173 |
| 48 | MP0006082_CNS_inflammation | 1.24505070 |
| 49 | MP0002736_abnormal_nociception_after | 1.22500524 |
| 50 | MP0005332_abnormal_amino_acid | 1.19314777 |
| 51 | MP0004147_increased_porphyrin_level | 1.18337990 |
| 52 | MP0002723_abnormal_immune_serum | 1.16800341 |
| 53 | MP0003121_genomic_imprinting | 1.16324360 |
| 54 | MP0003763_abnormal_thymus_physiology | 1.15623081 |
| 55 | MP0006054_spinal_hemorrhage | 1.13211972 |
| 56 | MP0001968_abnormal_touch/_nociception | 1.12397636 |
| 57 | MP0001845_abnormal_inflammatory_respons | 1.11138549 |
| 58 | MP0003693_abnormal_embryo_hatching | 1.09923920 |
| 59 | MP0005220_abnormal_exocrine_pancreas | 1.07996451 |
| 60 | MP0002420_abnormal_adaptive_immunity | 1.06706888 |
| 61 | MP0003866_abnormal_defecation | 1.06580111 |
| 62 | MP0005636_abnormal_mineral_homeostasis | 1.06377615 |
| 63 | MP0002452_abnormal_antigen_presenting | 1.06148602 |
| 64 | MP0001819_abnormal_immune_cell | 1.04913145 |
| 65 | MP0002277_abnormal_respiratory_mucosa | 1.04091615 |
| 66 | MP0000427_abnormal_hair_cycle | 1.03767556 |
| 67 | MP0001764_abnormal_homeostasis | 1.03382891 |
| 68 | MP0010155_abnormal_intestine_physiology | 1.02459188 |
| 69 | MP0001984_abnormal_olfaction | 1.01358009 |
| 70 | MP0004957_abnormal_blastocyst_morpholog | 1.01227817 |
| 71 | MP0009046_muscle_twitch | 1.00561246 |
| 72 | MP0000689_abnormal_spleen_morphology | 0.97712489 |
| 73 | MP0003252_abnormal_bile_duct | 0.97418706 |
| 74 | MP0001944_abnormal_pancreas_morphology | 0.95038890 |
| 75 | MP0002751_abnormal_autonomic_nervous | 0.94344892 |
| 76 | MP0004215_abnormal_myocardial_fiber | 0.91872489 |
| 77 | MP0001919_abnormal_reproductive_system | 0.90458842 |
| 78 | MP0009764_decreased_sensitivity_to | 0.90242877 |
| 79 | MP0001986_abnormal_taste_sensitivity | 0.89047208 |
| 80 | MP0001661_extended_life_span | 0.88000318 |
| 81 | MP0005389_reproductive_system_phenotype | 0.87805907 |
| 82 | MP0005025_abnormal_response_to | 0.81743261 |
| 83 | MP0001905_abnormal_dopamine_level | 0.80909675 |
| 84 | MP0008469_abnormal_protein_level | 0.79785025 |
| 85 | MP0008873_increased_physiological_sensi | 0.78995991 |
| 86 | MP0005365_abnormal_bile_salt | 0.78603823 |
| 87 | MP0000716_abnormal_immune_system | 0.77800481 |
| 88 | MP0003880_abnormal_central_pattern | 0.77188924 |
| 89 | MP0004043_abnormal_pH_regulation | 0.77104457 |
| 90 | MP0003111_abnormal_nucleus_morphology | 0.76250786 |
| 91 | MP0005410_abnormal_fertilization | 0.75699879 |
| 92 | MP0002398_abnormal_bone_marrow | 0.75084655 |
| 93 | MP0005319_abnormal_enzyme/_coenzyme | 0.75058282 |
| 94 | MP0002928_abnormal_bile_duct | 0.73689688 |
| 95 | MP0008775_abnormal_heart_ventricle | 0.73345292 |
| 96 | MP0001529_abnormal_vocalization | 0.73000080 |
| 97 | MP0002090_abnormal_vision | 0.71546478 |
| 98 | MP0000358_abnormal_cell_content/ | 0.70771460 |
| 99 | MP0001501_abnormal_sleep_pattern | 0.69734646 |
| 100 | MP0002722_abnormal_immune_system | 0.67683242 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.16917406 |
| 2 | Progressive macrocephaly (HP:0004481) | 3.86109367 |
| 3 | Mitochondrial inheritance (HP:0001427) | 3.76290319 |
| 4 | Increased CSF lactate (HP:0002490) | 3.72691592 |
| 5 | Acute encephalopathy (HP:0006846) | 3.71037560 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.66701269 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.37141936 |
| 8 | Hepatic necrosis (HP:0002605) | 3.33673601 |
| 9 | Hypothermia (HP:0002045) | 3.26040745 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.24820741 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.23790669 |
| 12 | Methylmalonic acidemia (HP:0002912) | 3.16880428 |
| 13 | Stomatitis (HP:0010280) | 2.87849969 |
| 14 | Methylmalonic aciduria (HP:0012120) | 2.85402803 |
| 15 | Ketoacidosis (HP:0001993) | 2.83142155 |
| 16 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.82236465 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.82236465 |
| 18 | Cerebral edema (HP:0002181) | 2.80676074 |
| 19 | Renal Fanconi syndrome (HP:0001994) | 2.80472701 |
| 20 | 3-Methylglutaconic aciduria (HP:0003535) | 2.76239832 |
| 21 | Congenital, generalized hypertrichosis (HP:0004540) | 2.75687685 |
| 22 | Renal cortical cysts (HP:0000803) | 2.67635006 |
| 23 | Increased serum lactate (HP:0002151) | 2.63838756 |
| 24 | Pancreatic cysts (HP:0001737) | 2.60323710 |
| 25 | Hypoglycemic coma (HP:0001325) | 2.59617334 |
| 26 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.54605805 |
| 27 | Thyroiditis (HP:0100646) | 2.52874843 |
| 28 | Lactic acidosis (HP:0003128) | 2.51279750 |
| 29 | Hypoproteinemia (HP:0003075) | 2.46199777 |
| 30 | Abnormality of the renal cortex (HP:0011035) | 2.45379974 |
| 31 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.42008996 |
| 32 | Abnormality of vitamin B metabolism (HP:0004340) | 2.41766189 |
| 33 | IgG deficiency (HP:0004315) | 2.40887216 |
| 34 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.35199712 |
| 35 | Hypoglycemic seizures (HP:0002173) | 2.34852993 |
| 36 | Glycosuria (HP:0003076) | 2.32651531 |
| 37 | Abnormality of urine glucose concentration (HP:0011016) | 2.32651531 |
| 38 | Hyperglycemia (HP:0003074) | 2.32650334 |
| 39 | Degeneration of anterior horn cells (HP:0002398) | 2.32615787 |
| 40 | Abnormality of the anterior horn cell (HP:0006802) | 2.32615787 |
| 41 | Lethargy (HP:0001254) | 2.31812584 |
| 42 | Respiratory failure (HP:0002878) | 2.31682663 |
| 43 | Congenital stationary night blindness (HP:0007642) | 2.31649749 |
| 44 | Abnormality of midbrain morphology (HP:0002418) | 2.30586392 |
| 45 | Molar tooth sign on MRI (HP:0002419) | 2.30586392 |
| 46 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.27719342 |
| 47 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.27719342 |
| 48 | Generalized aminoaciduria (HP:0002909) | 2.26291992 |
| 49 | Tongue fasciculations (HP:0001308) | 2.25896209 |
| 50 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.25224323 |
| 51 | Pancreatic fibrosis (HP:0100732) | 2.24292786 |
| 52 | Increased intramyocellular lipid droplets (HP:0012240) | 2.23588628 |
| 53 | Ketosis (HP:0001946) | 2.23026285 |
| 54 | Aplastic anemia (HP:0001915) | 2.21812497 |
| 55 | Exertional dyspnea (HP:0002875) | 2.21382080 |
| 56 | Severe combined immunodeficiency (HP:0004430) | 2.19194503 |
| 57 | Optic disc pallor (HP:0000543) | 2.18964147 |
| 58 | Type I transferrin isoform profile (HP:0003642) | 2.17996945 |
| 59 | True hermaphroditism (HP:0010459) | 2.15222050 |
| 60 | Abnormality of methionine metabolism (HP:0010901) | 2.13245961 |
| 61 | Abnormality of the labia minora (HP:0012880) | 2.12306266 |
| 62 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.11860760 |
| 63 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.09870996 |
| 64 | Abolished electroretinogram (ERG) (HP:0000550) | 2.09755413 |
| 65 | Hypomagnesemia (HP:0002917) | 2.07040894 |
| 66 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.06501611 |
| 67 | Abnormal protein glycosylation (HP:0012346) | 2.06501611 |
| 68 | Abnormal glycosylation (HP:0012345) | 2.06501611 |
| 69 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.06501611 |
| 70 | Neoplasm of the adrenal gland (HP:0100631) | 2.04060345 |
| 71 | Progressive microcephaly (HP:0000253) | 2.01325129 |
| 72 | Dicarboxylic aciduria (HP:0003215) | 2.01269578 |
| 73 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.01269578 |
| 74 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.99868989 |
| 75 | Progressive inability to walk (HP:0002505) | 1.98308909 |
| 76 | Leukodystrophy (HP:0002415) | 1.96710667 |
| 77 | Palpitations (HP:0001962) | 1.96522677 |
| 78 | Pancytopenia (HP:0001876) | 1.95550506 |
| 79 | Exercise intolerance (HP:0003546) | 1.94177646 |
| 80 | Abnormality of T cell physiology (HP:0011840) | 1.94025877 |
| 81 | Abnormality of B cell number (HP:0010975) | 1.93357681 |
| 82 | Abnormality of the prostate (HP:0008775) | 1.93106216 |
| 83 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.91797413 |
| 84 | Symptomatic seizures (HP:0011145) | 1.88924959 |
| 85 | Abnormal drinking behavior (HP:0030082) | 1.87841863 |
| 86 | Polydipsia (HP:0001959) | 1.87841863 |
| 87 | Hyperglycinuria (HP:0003108) | 1.87553722 |
| 88 | Prominent metopic ridge (HP:0005487) | 1.86970597 |
| 89 | Increased muscle lipid content (HP:0009058) | 1.84595288 |
| 90 | B lymphocytopenia (HP:0010976) | 1.84303061 |
| 91 | Muscle fibrillation (HP:0010546) | 1.83375843 |
| 92 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.79073343 |
| 93 | Abnormality of glycine metabolism (HP:0010895) | 1.79073343 |
| 94 | Bile duct proliferation (HP:0001408) | 1.79038733 |
| 95 | Abnormal biliary tract physiology (HP:0012439) | 1.79038733 |
| 96 | Conjunctival hamartoma (HP:0100780) | 1.78104817 |
| 97 | Large for gestational age (HP:0001520) | 1.77492375 |
| 98 | Nephronophthisis (HP:0000090) | 1.77404783 |
| 99 | Hypoalbuminemia (HP:0003073) | 1.76633780 |
| 100 | Abnormal albumin level (HP:0012116) | 1.76633780 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 3.79728476 |
| 2 | MST4 | 3.04440097 |
| 3 | VRK2 | 2.84865765 |
| 4 | EIF2AK3 | 2.71188959 |
| 5 | NUAK1 | 2.70229931 |
| 6 | ZAK | 2.66583778 |
| 7 | TXK | 2.56837826 |
| 8 | TSSK6 | 2.52880530 |
| 9 | MAP4K2 | 2.32276147 |
| 10 | BMPR1B | 2.21510172 |
| 11 | TRIM28 | 2.19806025 |
| 12 | WNK3 | 2.01631601 |
| 13 | STK16 | 1.98748312 |
| 14 | BUB1 | 1.96291699 |
| 15 | VRK1 | 1.89079339 |
| 16 | MAP3K12 | 1.88098045 |
| 17 | GRK1 | 1.87044918 |
| 18 | EIF2AK1 | 1.83698777 |
| 19 | PLK3 | 1.76886435 |
| 20 | ADRBK2 | 1.74907143 |
| 21 | ACVR1B | 1.74520408 |
| 22 | TNIK | 1.71838404 |
| 23 | TLK1 | 1.65689830 |
| 24 | NEK1 | 1.62942196 |
| 25 | BCKDK | 1.59824113 |
| 26 | MKNK2 | 1.43725818 |
| 27 | SRPK1 | 1.33451518 |
| 28 | PLK2 | 1.24250495 |
| 29 | OXSR1 | 1.22167120 |
| 30 | BCR | 1.21605593 |
| 31 | CSNK1G3 | 1.19990489 |
| 32 | ERBB3 | 1.17247803 |
| 33 | MAP2K6 | 1.14739854 |
| 34 | INSRR | 1.14648634 |
| 35 | TAOK3 | 1.12708150 |
| 36 | CSNK1G1 | 1.12560316 |
| 37 | PHKG2 | 1.09972566 |
| 38 | PHKG1 | 1.09972566 |
| 39 | DAPK1 | 1.06691096 |
| 40 | WNK4 | 1.04568980 |
| 41 | CSNK1G2 | 1.02589408 |
| 42 | KDR | 0.96196408 |
| 43 | MKNK1 | 0.91163186 |
| 44 | BRSK2 | 0.88265621 |
| 45 | STK39 | 0.87474625 |
| 46 | TAF1 | 0.87388312 |
| 47 | MAP4K1 | 0.85404208 |
| 48 | PLK4 | 0.84376760 |
| 49 | IKBKB | 0.83295785 |
| 50 | MAPKAPK3 | 0.82502275 |
| 51 | FER | 0.81524986 |
| 52 | TEC | 0.79471677 |
| 53 | TIE1 | 0.77070871 |
| 54 | EIF2AK2 | 0.76897905 |
| 55 | CSNK1A1L | 0.75633869 |
| 56 | MYLK | 0.74656958 |
| 57 | TTK | 0.70342613 |
| 58 | PRKCE | 0.70175768 |
| 59 | STK38L | 0.70067437 |
| 60 | PASK | 0.68662151 |
| 61 | SIK3 | 0.67282815 |
| 62 | FGFR2 | 0.66648196 |
| 63 | LIMK1 | 0.66485690 |
| 64 | NME1 | 0.66117700 |
| 65 | PBK | 0.65181679 |
| 66 | NLK | 0.63512066 |
| 67 | WEE1 | 0.63043226 |
| 68 | PAK3 | 0.61440944 |
| 69 | KIT | 0.61186185 |
| 70 | BMPR2 | 0.60968887 |
| 71 | ITK | 0.60208014 |
| 72 | PINK1 | 0.59464639 |
| 73 | MAPK13 | 0.59117917 |
| 74 | PLK1 | 0.55186531 |
| 75 | CDC7 | 0.54959006 |
| 76 | STK3 | 0.54703657 |
| 77 | EPHA3 | 0.53125367 |
| 78 | ATR | 0.51622857 |
| 79 | PRKCQ | 0.50885237 |
| 80 | TESK1 | 0.47302477 |
| 81 | IKBKE | 0.44400183 |
| 82 | PRKCI | 0.44301390 |
| 83 | FLT3 | 0.43094265 |
| 84 | MAP3K14 | 0.41863018 |
| 85 | SCYL2 | 0.41740243 |
| 86 | MAPKAPK5 | 0.39461116 |
| 87 | ALK | 0.39187499 |
| 88 | LYN | 0.38867882 |
| 89 | IRAK1 | 0.38751353 |
| 90 | RPS6KA5 | 0.37560698 |
| 91 | FES | 0.36859324 |
| 92 | ATM | 0.36357088 |
| 93 | CAMKK2 | 0.36352976 |
| 94 | CSNK1A1 | 0.35906289 |
| 95 | PTK2B | 0.35739990 |
| 96 | PRKCG | 0.35512669 |
| 97 | CSNK2A1 | 0.35480822 |
| 98 | SYK | 0.35232036 |
| 99 | CLK1 | 0.34932861 |
| 100 | PAK4 | 0.34139437 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.58494447 |
| 2 | Protein export_Homo sapiens_hsa03060 | 4.24030303 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.75063702 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.20493553 |
| 5 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.14410886 |
| 6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.10251685 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.08925621 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.08500211 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.07839681 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.02988235 |
| 11 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.87606277 |
| 12 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.86126634 |
| 13 | Allograft rejection_Homo sapiens_hsa05330 | 1.85626446 |
| 14 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.81582580 |
| 15 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.80560819 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.73703168 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.73351331 |
| 18 | Mismatch repair_Homo sapiens_hsa03430 | 1.70164417 |
| 19 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.66942533 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.64298887 |
| 21 | Asthma_Homo sapiens_hsa05310 | 1.58428537 |
| 22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.57174679 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.54739838 |
| 24 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.52862104 |
| 25 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.51184245 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.45284119 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.44458531 |
| 28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.43797077 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.43781901 |
| 30 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.37410886 |
| 31 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.34227678 |
| 32 | DNA replication_Homo sapiens_hsa03030 | 1.33263449 |
| 33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.32551991 |
| 34 | Phototransduction_Homo sapiens_hsa04744 | 1.31315556 |
| 35 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.24815153 |
| 36 | Alzheimers disease_Homo sapiens_hsa05010 | 1.23177737 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.22193587 |
| 38 | Huntingtons disease_Homo sapiens_hsa05016 | 1.21427544 |
| 39 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.18583563 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.18135672 |
| 41 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.15476999 |
| 42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.14405293 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.13114071 |
| 44 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.10565540 |
| 45 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.09852598 |
| 46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.06044965 |
| 47 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.03832687 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 1.03430841 |
| 49 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.01021781 |
| 50 | Base excision repair_Homo sapiens_hsa03410 | 1.01021144 |
| 51 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.99564226 |
| 52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.99089152 |
| 53 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.95676531 |
| 54 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.94053201 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.93725076 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.93115948 |
| 57 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.89324345 |
| 58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.86321010 |
| 59 | Spliceosome_Homo sapiens_hsa03040 | 0.83779253 |
| 60 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.83709334 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.83624226 |
| 62 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.79807374 |
| 63 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.79039893 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.75655632 |
| 65 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.71589576 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.71507649 |
| 67 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.71415890 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67167179 |
| 69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64888279 |
| 70 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.64296321 |
| 71 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.61366027 |
| 72 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.61260421 |
| 73 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.60946895 |
| 74 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.60496171 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.60395858 |
| 76 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.58362377 |
| 77 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.55947313 |
| 78 | Legionellosis_Homo sapiens_hsa05134 | 0.54871873 |
| 79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.53712550 |
| 80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.53601162 |
| 81 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.49864290 |
| 82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48712839 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48289090 |
| 84 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.47960868 |
| 85 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.44650853 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44092075 |
| 87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43555420 |
| 88 | Retinol metabolism_Homo sapiens_hsa00830 | 0.41823363 |
| 89 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.41313736 |
| 90 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41292751 |
| 91 | Carbon metabolism_Homo sapiens_hsa01200 | 0.39704924 |
| 92 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.38257455 |
| 93 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37680852 |
| 94 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.37270531 |
| 95 | Viral myocarditis_Homo sapiens_hsa05416 | 0.35618583 |
| 96 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.35321949 |
| 97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34738916 |
| 98 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.34396351 |
| 99 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.34348001 |
| 100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.34338460 |

