SPOCK1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.94779987
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.90574993
3synaptic vesicle exocytosis (GO:0016079)5.52645265
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.47773854
5glutamate secretion (GO:0014047)5.33729036
6locomotory exploration behavior (GO:0035641)5.24542389
7regulation of synaptic vesicle exocytosis (GO:2000300)5.15177103
8neuronal action potential propagation (GO:0019227)5.14933414
9vocalization behavior (GO:0071625)5.04693992
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.02106048
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.74208264
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.70136380
13neuron cell-cell adhesion (GO:0007158)4.55184651
14neurotransmitter secretion (GO:0007269)4.53305758
15regulation of synaptic vesicle transport (GO:1902803)4.51813811
16regulation of glutamate receptor signaling pathway (GO:1900449)4.39847678
17protein localization to synapse (GO:0035418)4.38007669
18regulation of neuronal synaptic plasticity (GO:0048168)4.14136390
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.13061078
20exploration behavior (GO:0035640)4.12388764
21layer formation in cerebral cortex (GO:0021819)4.07693008
22regulation of long-term neuronal synaptic plasticity (GO:0048169)3.97696522
23gamma-aminobutyric acid transport (GO:0015812)3.97289537
24cellular potassium ion homeostasis (GO:0030007)3.86568296
25membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.86352478
26synaptic transmission, glutamatergic (GO:0035249)3.84431215
27neuromuscular process controlling posture (GO:0050884)3.80440306
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.78900002
29proline transport (GO:0015824)3.75118039
30cerebellar Purkinje cell differentiation (GO:0021702)3.73301308
31dendritic spine morphogenesis (GO:0060997)3.71692550
32neurotransmitter transport (GO:0006836)3.71154858
33glutamate receptor signaling pathway (GO:0007215)3.70557785
34regulation of synapse structural plasticity (GO:0051823)3.70393643
35neuron-neuron synaptic transmission (GO:0007270)3.67537695
36activation of protein kinase A activity (GO:0034199)3.64712456
37amino acid import (GO:0043090)3.59989361
38neuron recognition (GO:0008038)3.57844952
39long-term memory (GO:0007616)3.53809439
40sodium ion export (GO:0071436)3.50709037
41neurotransmitter-gated ion channel clustering (GO:0072578)3.49443084
42positive regulation of membrane potential (GO:0045838)3.46426191
43L-amino acid import (GO:0043092)3.44243977
44regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.41382883
45regulation of neurotransmitter secretion (GO:0046928)3.41342469
46regulation of excitatory postsynaptic membrane potential (GO:0060079)3.41207151
47axonal fasciculation (GO:0007413)3.40740541
48regulation of neurotransmitter levels (GO:0001505)3.39725737
49positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.39536149
50transmission of nerve impulse (GO:0019226)3.35698921
51negative regulation of synaptic transmission, GABAergic (GO:0032229)3.32133202
52neuromuscular process controlling balance (GO:0050885)3.32013694
53cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.31742376
54regulation of postsynaptic membrane potential (GO:0060078)3.31305222
55glycine transport (GO:0015816)3.29357738
56regulation of synaptic plasticity (GO:0048167)3.29302931
57synaptic vesicle endocytosis (GO:0048488)3.26835560
58membrane depolarization during action potential (GO:0086010)3.23893820
59axon ensheathment in central nervous system (GO:0032291)3.21804950
60central nervous system myelination (GO:0022010)3.21804950
61cytoskeletal anchoring at plasma membrane (GO:0007016)3.21802565
62gamma-aminobutyric acid signaling pathway (GO:0007214)3.20569825
63postsynaptic membrane organization (GO:0001941)3.17161942
64regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.16610813
65dendrite morphogenesis (GO:0048813)3.13239550
66positive regulation of fibroblast migration (GO:0010763)3.12939504
67cell migration in hindbrain (GO:0021535)3.12828222
68regulation of neurotransmitter transport (GO:0051588)3.12218108
69regulation of vesicle fusion (GO:0031338)3.11594216
70positive regulation of synapse maturation (GO:0090129)3.10642076
71membrane hyperpolarization (GO:0060081)3.09647902
72cell communication by electrical coupling (GO:0010644)3.09391134
73auditory behavior (GO:0031223)3.07351359
74long-term synaptic potentiation (GO:0060291)3.07251232
75presynaptic membrane assembly (GO:0097105)3.07125484
76innervation (GO:0060384)3.06076717
77potassium ion import (GO:0010107)3.06026223
78response to auditory stimulus (GO:0010996)3.05687572
79vesicle transport along microtubule (GO:0047496)3.04829429
80positive regulation of synaptic transmission, GABAergic (GO:0032230)3.04823617
81presynaptic membrane organization (GO:0097090)3.04734234
82cellular sodium ion homeostasis (GO:0006883)3.03364786
83regulation of synaptic transmission, glutamatergic (GO:0051966)3.02723464
84synapse assembly (GO:0007416)3.01863679
85neuronal ion channel clustering (GO:0045161)3.01264136
86peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.00873147
87membrane depolarization (GO:0051899)3.00844810
88regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.99215075
89neuromuscular process (GO:0050905)2.97850214
90cerebellar granule cell differentiation (GO:0021707)2.96013673
91adult walking behavior (GO:0007628)2.94847329
92positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.94596501
93cerebellar Purkinje cell layer development (GO:0021680)2.94269069
94detection of calcium ion (GO:0005513)2.94107803
95calcium ion-dependent exocytosis (GO:0017156)2.93680517
96synaptic transmission (GO:0007268)2.91789917
97positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.91713925
98organelle transport along microtubule (GO:0072384)2.90350091
99positive regulation of dendritic spine development (GO:0060999)2.90020325
100regulation of dendritic spine morphogenesis (GO:0061001)2.89138999
101regulation of ARF protein signal transduction (GO:0032012)2.88271004
102regulation of synapse maturation (GO:0090128)2.87582547
103regulation of synaptic transmission (GO:0050804)2.86107475
104G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.86059915
105negative regulation of microtubule polymerization (GO:0031115)2.85241357
106positive regulation of potassium ion transmembrane transport (GO:1901381)2.83438215
107regulation of voltage-gated calcium channel activity (GO:1901385)2.83342658
108mating behavior (GO:0007617)2.83277989
109negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.83090048
110positive regulation of neurotransmitter transport (GO:0051590)2.80084350
111potassium ion homeostasis (GO:0055075)2.79132599
112learning (GO:0007612)2.76053428
113synapse organization (GO:0050808)2.75714201
114positive regulation of synapse assembly (GO:0051965)2.72780220
115collagen fibril organization (GO:0030199)2.70479583
116negative regulation of dendrite morphogenesis (GO:0050774)2.69092453
117membrane assembly (GO:0071709)2.64258247
118response to gravity (GO:0009629)2.52535539
119regulation of dendritic spine development (GO:0060998)2.51581145
120protein heterotrimerization (GO:0070208)2.51278372
121chondrocyte proliferation (GO:0035988)2.50368503
122acidic amino acid transport (GO:0015800)2.49165599
123axon extension (GO:0048675)2.47700488
124dendritic spine organization (GO:0097061)2.46701922
125positive regulation of axon extension (GO:0045773)2.46693708
126cell communication involved in cardiac conduction (GO:0086065)2.45174609
127positive regulation of dendritic spine morphogenesis (GO:0061003)2.42978297
128positive regulation of neurotransmitter secretion (GO:0001956)2.42375009

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.19242669
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.62002362
3GBX2_23144817_ChIP-Seq_PC3_Human3.41910320
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.10224207
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.01315192
6* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.01201899
7REST_21632747_ChIP-Seq_MESCs_Mouse2.73028699
8* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.72563228
9* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.72563228
10PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.69482694
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.66635059
12* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.54349754
13* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.54318982
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.52257475
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.50959652
16* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.46546987
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.46133169
18DROSHA_22980978_ChIP-Seq_HELA_Human2.45499756
19RARB_27405468_Chip-Seq_BRAIN_Mouse2.36210585
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.29401012
21* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26084178
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.25286739
23* REST_18959480_ChIP-ChIP_MESCs_Mouse2.20485058
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.20109822
25IKZF1_21737484_ChIP-ChIP_HCT116_Human1.96436722
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.93909858
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.91134427
28THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.90976683
29GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.85528287
30* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.80756400
31* CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.75520967
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.73777786
33TAF15_26573619_Chip-Seq_HEK293_Human1.73734258
34AR_21572438_ChIP-Seq_LNCaP_Human1.73660914
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.72022565
36SMAD4_21799915_ChIP-Seq_A2780_Human1.62640404
37* MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.56480532
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55691801
39EP300_21415370_ChIP-Seq_HL-1_Mouse1.55303931
40* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.50485771
41ERG_21242973_ChIP-ChIP_JURKAT_Human1.50267770
42EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.45018648
43RARG_19884340_ChIP-ChIP_MEFs_Mouse1.44837792
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.43590152
45NR3C1_23031785_ChIP-Seq_PC12_Mouse1.36276256
46* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.35966472
47PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34870093
48TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34456548
49BMI1_23680149_ChIP-Seq_NPCS_Mouse1.33535315
50P300_19829295_ChIP-Seq_ESCs_Human1.33479609
51ESR2_21235772_ChIP-Seq_MCF-7_Human1.33388251
52* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.31915593
53RING1B_27294783_Chip-Seq_ESCs_Mouse1.31077282
54* SOX2_21211035_ChIP-Seq_LN229_Gbm1.30851513
55* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28561093
56* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.28516920
57ZFP281_27345836_Chip-Seq_ESCs_Mouse1.27217917
58RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27178366
59WT1_19549856_ChIP-ChIP_CCG9911_Human1.27143249
60ZNF274_21170338_ChIP-Seq_K562_Hela1.26979455
61CTNNB1_20460455_ChIP-Seq_HCT116_Human1.25490745
62TP53_18474530_ChIP-ChIP_U2OS_Human1.23376961
63IGF1R_20145208_ChIP-Seq_DFB_Human1.22796817
64* STAT3_23295773_ChIP-Seq_U87_Human1.22162589
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21668715
66* SMAD3_21741376_ChIP-Seq_EPCs_Human1.21318090
67* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20485023
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20479452
69TP53_16413492_ChIP-PET_HCT116_Human1.20184345
70CBX2_27304074_Chip-Seq_ESCs_Mouse1.18361983
71AR_19668381_ChIP-Seq_PC3_Human1.18326419
72* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15052066
73DNAJC2_21179169_ChIP-ChIP_NT2_Human1.15047584
74* AR_25329375_ChIP-Seq_VCAP_Human1.14563199
75GATA2_21666600_ChIP-Seq_HMVEC_Human1.13479544
76ARNT_22903824_ChIP-Seq_MCF-7_Human1.12382233
77AHR_22903824_ChIP-Seq_MCF-7_Human1.11647518
78* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.10343184
79CDX2_19796622_ChIP-Seq_MESCs_Mouse1.09987753
80RING1B_27294783_Chip-Seq_NPCs_Mouse1.09822676
81* PIAS1_25552417_ChIP-Seq_VCAP_Human1.09794419
82RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.09163272
83NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.08589385
84NRF2_20460467_ChIP-Seq_MEFs_Mouse1.08589385
85* RNF2_27304074_Chip-Seq_NSC_Mouse1.08427534
86ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08140766
87TP53_20018659_ChIP-ChIP_R1E_Mouse1.07946551
88* CJUN_26792858_Chip-Seq_BT549_Human1.07270809
89KDM2B_26808549_Chip-Seq_K562_Human1.07074086
90* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06615170
91SMAD_19615063_ChIP-ChIP_OVARY_Human1.05547588
92P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04732161
93* TP53_23651856_ChIP-Seq_MEFs_Mouse1.04164197
94SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.04151887
95* TCF4_23295773_ChIP-Seq_U87_Human1.03805611
96YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02919251
97* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02762505
98OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.02307902
99* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01615464
100GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01081367
101TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00221895
102SMAD3_21741376_ChIP-Seq_ESCs_Human0.99567098
103MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98918315
104NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95795726
105* RUNX2_22187159_ChIP-Seq_PCA_Human0.95715277
106WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.95459321
107* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.95315967
108TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95040325
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.94732258
110RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.94564941
111SMAD4_21741376_ChIP-Seq_HESCs_Human0.92826625
112BRD4_25478319_ChIP-Seq_HGPS_Human0.92670419
113ZFP281_18757296_ChIP-ChIP_E14_Mouse0.92521859
114ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91442477
115PRDM14_20953172_ChIP-Seq_ESCs_Human0.91055849
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90946278
117CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.90764967
118POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90747220
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90747220
120POU3F2_20337985_ChIP-ChIP_501MEL_Human0.90307788
121PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.89387797
122VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.89243048
123ISL1_27105846_Chip-Seq_CPCs_Mouse0.87915140
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86798468
125TET1_21490601_ChIP-Seq_MESCs_Mouse0.86016231
126CLOCK_20551151_ChIP-Seq_293T_Human0.85453131
127P300_27058665_Chip-Seq_ZR-75-30cells_Human0.83383593
128GATA1_26923725_Chip-Seq_HPCs_Mouse0.83246334
129UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.82831437
130TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82585251
131LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82558109
132RXR_22108803_ChIP-Seq_LS180_Human0.82533157
133SMAD4_21741376_ChIP-Seq_EPCs_Human0.82302746
134NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.81393165
135ER_23166858_ChIP-Seq_MCF-7_Human0.80755301

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.80809960
2MP0008438_abnormal_cutaneous_collagen4.76053723
3MP0003880_abnormal_central_pattern4.41440505
4MP0003635_abnormal_synaptic_transmissio3.99336688
5MP0004270_analgesia3.92915766
6MP0009046_muscle_twitch3.31135446
7MP0009745_abnormal_behavioral_response3.17265441
8MP0002064_seizures3.13240782
9MP0002063_abnormal_learning/memory/cond3.07336280
10MP0002734_abnormal_mechanical_nocicepti2.81898107
11MP0005423_abnormal_somatic_nervous2.79339951
12MP0002272_abnormal_nervous_system2.78222075
13MP0001968_abnormal_touch/_nociception2.76590572
14MP0002572_abnormal_emotion/affect_behav2.65191444
15MP0001486_abnormal_startle_reflex2.63137610
16MP0005503_abnormal_tendon_morphology2.62474723
17MP0003705_abnormal_hypodermis_morpholog2.57494428
18MP0003279_aneurysm2.50814812
19MP0001984_abnormal_olfaction2.41462193
20MP0001958_emphysema2.40567857
21MP0002735_abnormal_chemical_nociception2.39424956
22MP0001501_abnormal_sleep_pattern2.18268188
23MP0002733_abnormal_thermal_nociception2.12831466
24MP0005275_abnormal_skin_tensile2.09557393
25MP0002067_abnormal_sensory_capabilities2.06808624
26MP0001970_abnormal_pain_threshold2.06779752
27MP0002184_abnormal_innervation2.05570885
28MP0008569_lethality_at_weaning2.05536738
29MP0006276_abnormal_autonomic_nervous2.03377099
30MP0004858_abnormal_nervous_system2.02843782
31MP0002822_catalepsy2.01641732
32MP0002736_abnormal_nociception_after2.01586907
33MP0004272_abnormal_basement_membrane2.00937410
34MP0001440_abnormal_grooming_behavior1.96649380
35MP0003879_abnormal_hair_cell1.94107347
36MP0003329_amyloid_beta_deposits1.93919996
37MP0009780_abnormal_chondrocyte_physiolo1.93223340
38MP0005645_abnormal_hypothalamus_physiol1.83100714
39MP0000778_abnormal_nervous_system1.82566502
40MP0002557_abnormal_social/conspecific_i1.79124452
41MP0004811_abnormal_neuron_physiology1.77103629
42MP0002909_abnormal_adrenal_gland1.76802661
43MP0000955_abnormal_spinal_cord1.69663708
44MP0005646_abnormal_pituitary_gland1.68942273
45MP0004924_abnormal_behavior1.66282936
46MP0005386_behavior/neurological_phenoty1.66282936
47MP0004142_abnormal_muscle_tone1.58004978
48MP0004885_abnormal_endolymph1.54735696
49MP0002882_abnormal_neuron_morphology1.52814293
50MP0010368_abnormal_lymphatic_system1.51816584
51MP0005257_abnormal_intraocular_pressure1.46001809
52MP0002066_abnormal_motor_capabilities/c1.45086143
53MP0003122_maternal_imprinting1.41758631
54MP0003633_abnormal_nervous_system1.37165814
55MP0003787_abnormal_imprinting1.32497976
56MP0001502_abnormal_circadian_rhythm1.31867840
57MP0003566_abnormal_cell_adhesion1.31436846
58MP0001485_abnormal_pinna_reflex1.23915150
59MP0003283_abnormal_digestive_organ1.21683440
60MP0002295_abnormal_pulmonary_circulatio1.20354520
61MP0004742_abnormal_vestibular_system1.20268001
62MP0002229_neurodegeneration1.17691713
63MP0003631_nervous_system_phenotype1.15780155
64MP0000534_abnormal_ureter_morphology1.14321059
65MP0001529_abnormal_vocalization1.12971133
66MP0002152_abnormal_brain_morphology1.10580867
67MP0009384_cardiac_valve_regurgitation1.08144051
68MP0001963_abnormal_hearing_physiology1.07302863
69MP0004145_abnormal_muscle_electrophysio1.06864839
70MP0005508_abnormal_skeleton_morphology1.05807612
71MP0000920_abnormal_myelination1.05427329
72MP0001905_abnormal_dopamine_level1.05408485
73MP0010386_abnormal_urinary_bladder1.04782336
74MP0005394_taste/olfaction_phenotype1.03888669
75MP0005499_abnormal_olfactory_system1.03888669
76MP0003091_abnormal_cell_migration1.03468506
77MP0003634_abnormal_glial_cell1.01916854
78MP0000013_abnormal_adipose_tissue0.99215259
79MP0005171_absent_coat_pigmentation0.96918309
80MP0009250_abnormal_appendicular_skeleto0.96294491
81MP0004043_abnormal_pH_regulation0.93737883
82MP0005595_abnormal_vascular_smooth0.92319627
83MP0002752_abnormal_somatic_nervous0.91786998
84MP0003385_abnormal_body_wall0.91277389
85MP0000751_myopathy0.89219524
86MP0002896_abnormal_bone_mineralization0.88979503
87MP0002069_abnormal_eating/drinking_beha0.88647492
88MP0005551_abnormal_eye_electrophysiolog0.86686386
89MP0001188_hyperpigmentation0.85413416
90MP0003632_abnormal_nervous_system0.84293353
91MP0001879_abnormal_lymphatic_vessel0.83311801
92MP0001177_atelectasis0.83085182
93MP0005409_darkened_coat_color0.82949009
94MP0000767_abnormal_smooth_muscle0.82832406
95MP0008872_abnormal_physiological_respon0.82371153
96MP0003690_abnormal_glial_cell0.81939808
97MP0001299_abnormal_eye_distance/0.81634943
98MP0000604_amyloidosis0.80912269
99MP0000631_abnormal_neuroendocrine_gland0.80507752
100MP0002108_abnormal_muscle_morphology0.80251520
101MP0005535_abnormal_body_temperature0.79806545
102MP0004085_abnormal_heartbeat0.79322421
103MP0008874_decreased_physiological_sensi0.76886422
104MP0005388_respiratory_system_phenotype0.75184592
105MP0002133_abnormal_respiratory_system0.75184592
106MP0001542_abnormal_bone_strength0.73402267
107MP0002837_dystrophic_cardiac_calcinosis0.73163859
108MP0005023_abnormal_wound_healing0.72089886
109MP0002638_abnormal_pupillary_reflex0.71104504
110MP0005623_abnormal_meninges_morphology0.68472277
111MP0000026_abnormal_inner_ear0.68217059
112MP0010030_abnormal_orbit_morphology0.68105398
113MP0000749_muscle_degeneration0.65524727
114MP0003950_abnormal_plasma_membrane0.65511374
115MP0001348_abnormal_lacrimal_gland0.65149090
116MP0000569_abnormal_digit_pigmentation0.64720050
117MP0004134_abnormal_chest_morphology0.63296847
118MP0003045_fibrosis0.63097365
119MP0008961_abnormal_basal_metabolism0.61269042
120MP0003942_abnormal_urinary_system0.60905900
121MP0001943_abnormal_respiration0.59630165
122MP0002876_abnormal_thyroid_physiology0.58318071
123MP0000759_abnormal_skeletal_muscle0.57354227
124MP0003137_abnormal_impulse_conducting0.57339218
125MP0002060_abnormal_skin_morphology0.57164836
126MP0000762_abnormal_tongue_morphology0.56928793
127MP0000428_abnormal_craniofacial_morphol0.56729450
128MP0000462_abnormal_digestive_system0.56706023
129MP0003075_altered_response_to0.56402066
130MP0010769_abnormal_survival0.55966507
131MP0003861_abnormal_nervous_system0.55509172
132MP0002082_postnatal_lethality0.55277387
133MP0010770_preweaning_lethality0.55277387
134MP0004215_abnormal_myocardial_fiber0.54904280
135MP0002090_abnormal_vision0.54292161
136MP0003183_abnormal_peptide_metabolism0.52769688
137MP0004233_abnormal_muscle_weight0.52525935
138MP0005187_abnormal_penis_morphology0.52507468
139MP0010768_mortality/aging0.52028033

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.13838514
2Myokymia (HP:0002411)6.70186097
3Focal seizures (HP:0007359)5.61114740
4Protrusio acetabuli (HP:0003179)5.56224242
5Premature rupture of membranes (HP:0001788)5.10245631
6Visual hallucinations (HP:0002367)5.01342431
7Atonic seizures (HP:0010819)5.00142418
8Febrile seizures (HP:0002373)4.75168308
9Epileptic encephalopathy (HP:0200134)4.54338603
10Progressive cerebellar ataxia (HP:0002073)4.34498460
11Action tremor (HP:0002345)4.31854817
12Absence seizures (HP:0002121)4.18088434
13Supranuclear gaze palsy (HP:0000605)3.95577852
14Generalized tonic-clonic seizures (HP:0002069)3.87257105
15Dialeptic seizures (HP:0011146)3.79408962
16Vascular tortuosity (HP:0004948)3.69763836
17Aortic dissection (HP:0002647)3.64083729
18Ankle clonus (HP:0011448)3.61893534
19Arterial tortuosity (HP:0005116)3.46789827
20Shallow orbits (HP:0000586)3.45737530
21Broad metatarsal (HP:0001783)3.41776955
22Aortic aneurysm (HP:0004942)3.21520385
23Depression (HP:0000716)3.21211054
24Truncal ataxia (HP:0002078)3.17332651
25Obstructive sleep apnea (HP:0002870)3.13042447
26Broad-based gait (HP:0002136)3.12175350
27Gaze-evoked nystagmus (HP:0000640)3.11091251
28Bladder diverticulum (HP:0000015)2.99880555
29Impaired vibration sensation in the lower limbs (HP:0002166)2.99155951
30Dysmetria (HP:0001310)2.97864071
31Poor eye contact (HP:0000817)2.95903562
32Urinary bladder sphincter dysfunction (HP:0002839)2.94693111
33Anxiety (HP:0000739)2.94035485
34Dysdiadochokinesis (HP:0002075)2.90089825
35Insidious onset (HP:0003587)2.88733597
36Termporal pattern (HP:0011008)2.88733597
37Soft skin (HP:0000977)2.86530002
38Mutism (HP:0002300)2.84809199
39Pheochromocytoma (HP:0002666)2.83699980
40Amblyopia (HP:0000646)2.81248167
41Abnormal eating behavior (HP:0100738)2.79989574
42Papilledema (HP:0001085)2.78592878
43Spastic gait (HP:0002064)2.77541974
44Postural instability (HP:0002172)2.77150937
45Ankle contracture (HP:0006466)2.74962790
46Wormian bones (HP:0002645)2.74875910
47Atrophic scars (HP:0001075)2.74454667
48Agitation (HP:0000713)2.73357059
49Abnormal social behavior (HP:0012433)2.72816559
50Impaired social interactions (HP:0000735)2.72816559
51Genetic anticipation (HP:0003743)2.72255343
52Hyperventilation (HP:0002883)2.71064552
53Neurofibrillary tangles (HP:0002185)2.68068865
54Scanning speech (HP:0002168)2.64032228
55Overgrowth (HP:0001548)2.62062970
56Abnormality of the corticospinal tract (HP:0002492)2.60263952
57Urinary urgency (HP:0000012)2.58259410
58Bowel diverticulosis (HP:0005222)2.58182427
59Impaired smooth pursuit (HP:0007772)2.53396019
60Neuroendocrine neoplasm (HP:0100634)2.53285802
61Mild short stature (HP:0003502)2.50801219
62Neonatal short-limb short stature (HP:0008921)2.50734071
63Abnormality of dentin (HP:0010299)2.50213558
64Limb dystonia (HP:0002451)2.49387868
65Excessive salivation (HP:0003781)2.49152428
66Drooling (HP:0002307)2.49152428
67Cerebral aneurysm (HP:0004944)2.48185884
68Genu recurvatum (HP:0002816)2.47202250
69Torticollis (HP:0000473)2.47154622
70Follicular hyperkeratosis (HP:0007502)2.46287508
71Hyperextensible skin (HP:0000974)2.45723049
72Hemiparesis (HP:0001269)2.44306927
73Cerebral inclusion bodies (HP:0100314)2.43085263
74Intention tremor (HP:0002080)2.42460161
75Epileptiform EEG discharges (HP:0011182)2.40165759
76Ventricular fibrillation (HP:0001663)2.39755262
77Progressive inability to walk (HP:0002505)2.38809370
78Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.36612698
79EEG with generalized epileptiform discharges (HP:0011198)2.36197546
80Spinal rigidity (HP:0003306)2.35077222
81Hemiplegia (HP:0002301)2.34749129
82Megalencephaly (HP:0001355)2.32915293
83Fragile skin (HP:0001030)2.32815886
84Retinal dysplasia (HP:0007973)2.29683672
85Abnormality of binocular vision (HP:0011514)2.28764886
86Diplopia (HP:0000651)2.28764886
87Focal dystonia (HP:0004373)2.28607585
88Annular pancreas (HP:0001734)2.28304815
89Bradykinesia (HP:0002067)2.27324224
90Hypsarrhythmia (HP:0002521)2.27076196
91Cervical subluxation (HP:0003308)2.26990388
92Absent speech (HP:0001344)2.24145884
93Hypoventilation (HP:0002791)2.23767292
94Type 1 muscle fiber predominance (HP:0003803)2.23521686
95Mitral valve prolapse (HP:0001634)2.22751629
96Lower limb muscle weakness (HP:0007340)2.21466939
97Upper limb amyotrophy (HP:0009129)2.17634365
98Distal upper limb amyotrophy (HP:0007149)2.17634365
99Stereotypic behavior (HP:0000733)2.14459676
100Hand muscle atrophy (HP:0009130)2.13534832
101Abnormality of ocular smooth pursuit (HP:0000617)2.12983707
102Abnormality of the lower motor neuron (HP:0002366)2.11183868
103Fetal akinesia sequence (HP:0001989)2.09442184
104Mitral regurgitation (HP:0001653)2.07431081
105Craniofacial dystonia (HP:0012179)2.05816123
106Status epilepticus (HP:0002133)2.05475984
107Spondylolisthesis (HP:0003302)2.03712623
108Dilatation of the ascending aorta (HP:0005111)2.02878920
109Wrist flexion contracture (HP:0001239)2.02606811
110Slender build (HP:0001533)2.00917173
111Polyphagia (HP:0002591)1.99064982
112Impaired vibratory sensation (HP:0002495)1.97866608
113Clonus (HP:0002169)1.97760518
114Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.96429971
115Degeneration of the lateral corticospinal tracts (HP:0002314)1.96429971
116Inability to walk (HP:0002540)1.95717754
117Generalized myoclonic seizures (HP:0002123)1.95581210
118Blue irides (HP:0000635)1.94697903
119Tetraplegia (HP:0002445)1.94211064
120Increased variability in muscle fiber diameter (HP:0003557)1.94003074
121Specific learning disability (HP:0001328)1.92995025
122Hammertoe (HP:0001765)1.92408744
123Gait ataxia (HP:0002066)1.91891824
124Hypoplasia of the iris (HP:0007676)1.90995879
125Lower limb amyotrophy (HP:0007210)1.90694770
126Psychosis (HP:0000709)1.89365050
127Vertebral compression fractures (HP:0002953)1.89056517
128Neuronal loss in central nervous system (HP:0002529)1.88315425
129Blue sclerae (HP:0000592)1.87669281
130Coronal craniosynostosis (HP:0004440)1.87008508
131Dysmetric saccades (HP:0000641)1.85967141
132Failure to thrive in infancy (HP:0001531)1.85621338
133Aplasia of the phalanges of the hand (HP:0009802)1.84241943
134Aplasia involving bones of the extremities (HP:0009825)1.84241943
135Aplasia involving bones of the upper limbs (HP:0009823)1.84241943
136Spinal cord compression (HP:0002176)1.84020915
137Gait imbalance (HP:0002141)1.83835890
138Abnormality of salivation (HP:0100755)1.83393112
139Neoplasm of the peripheral nervous system (HP:0100007)1.83193063
140Mitral stenosis (HP:0001718)1.82895783
141Insomnia (HP:0100785)1.82487814
142Aortic regurgitation (HP:0001659)1.80656768
143Cerebral hypomyelination (HP:0006808)1.80499968
144Abnormality of saccadic eye movements (HP:0000570)1.80189990
145Akinesia (HP:0002304)1.79670543
146Postural tremor (HP:0002174)1.78367106
147Renal duplication (HP:0000075)1.77980009
148Peripheral hypomyelination (HP:0007182)1.76975688
149Joint laxity (HP:0001388)1.76157860
150Rigidity (HP:0002063)1.76016585
151Anosmia (HP:0000458)1.74345271
152Sleep apnea (HP:0010535)1.74257947
153Incomplete penetrance (HP:0003829)1.73530309
154Delusions (HP:0000746)1.73327640
155Menstrual irregularities (HP:0000858)1.72267432
156Mildly elevated creatine phosphokinase (HP:0008180)1.71641398
157Turricephaly (HP:0000262)1.70976341
158Abnormal EKG (HP:0003115)1.70698191
159Wide anterior fontanel (HP:0000260)1.69861481
160Spinal canal stenosis (HP:0003416)1.67697226
161Aortic valve stenosis (HP:0001650)1.67135326
162Aneurysm (HP:0002617)1.66584769

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.34094927
2MAP3K93.62696729
3MARK13.12360782
4MAP3K43.02686557
5EPHA42.98913523
6MINK12.92576884
7MAP2K72.55502525
8NTRK12.49170479
9DAPK22.44676808
10PAK62.32315974
11RIPK12.24665945
12NTRK22.20208439
13PDGFRA2.13240178
14CASK2.11115960
15MAP3K122.04212893
16PRKD32.04062705
17MAP2K41.97426864
18KSR21.84841104
19CAMKK11.78282994
20CDK191.67353303
21CDK51.53942352
22UHMK11.53108744
23MAPK131.51271721
24TESK11.49591679
25CAMKK21.48763035
26PTK21.48286600
27GRK51.40939809
28PHKG21.40150311
29PHKG11.40150311
30ARAF1.37641937
31KSR11.33551681
32PNCK1.32935710
33MAP3K21.30569203
34STK381.28890537
35PLK21.28030175
36DAPK11.27227387
37PRKCG1.25790427
38TNIK1.24061992
39RIPK41.20843938
40MYLK1.20322285
41PAK21.16973927
42PRPF4B1.15818272
43SGK2231.13023980
44SGK4941.13023980
45OXSR11.12777271
46PAK31.11525532
47TIE11.07016870
48SIK21.01704071
49LATS20.98743697
50CAMK2A0.96550000
51TYRO30.96150191
52LMTK20.96075200
53MOS0.93984821
54PRKCH0.91983765
55TTN0.91786247
56CAMK2B0.90030874
57WNK10.89600364
58RET0.86864662
59CDK180.86633576
60STK110.85647256
61CDK140.85508878
62CDK150.83665858
63CAMK10.82450395
64SGK20.82021422
65CSNK1G20.80100087
66FES0.78980067
67TGFBR20.78602222
68NEK90.76632646
69PINK10.76047232
70TAOK10.75994334
71ROCK10.74759904
72PDGFRB0.73650541
73STK390.73144447
74CDK11A0.72010242
75SCYL20.71287026
76DAPK30.70987698
77SGK30.70053236
78DYRK1A0.68063493
79MAPK120.67614109
80CAMK2G0.66843819
81EPHB20.66757021
82CAMK2D0.66094292
83MARK20.65803163
84MET0.65448708
85MAP3K130.64698389
86ALK0.64305821
87ICK0.63908978
88BMPR20.63791666
89MAP3K10.62337785
90PRKCE0.61285592
91PDPK10.59905640
92PDK10.59380526
93CDC42BPA0.59001221
94SGK10.58318147
95TNK20.58064524
96FER0.56017525
97BRAF0.55764571
98PRKD20.55061287
99LIMK10.54729151
100CAMK1G0.52226574
101PRKG20.52168687
102FGFR20.51792462
103PRKCZ0.50769548
104BCR0.50303129
105NEK60.50218144
106WNK40.49621508
107SIK30.48896804
108AKT30.48809101
109DMPK0.48034430
110RAF10.47572329
111DDR20.46603425
112BRSK10.46596359
113RPS6KA20.45842197
114RPS6KA30.45246029
115MAP2K10.45172829
116WNK30.45150816
117ROCK20.44955167
118MAPK100.44107780
119MAPK70.43604010
120SRC0.43083661
121MAPKAPK50.42730793
122PKN10.41108759
123ERBB30.40687008
124PTK2B0.40564960
125FYN0.40442590
126CAMK40.40217380

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.48821865
2Nicotine addiction_Homo sapiens_hsa050333.40597246
3Olfactory transduction_Homo sapiens_hsa047403.15056251
4GABAergic synapse_Homo sapiens_hsa047272.70739415
5Circadian entrainment_Homo sapiens_hsa047132.57362427
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.55294443
7Glutamatergic synapse_Homo sapiens_hsa047242.45058324
8Long-term potentiation_Homo sapiens_hsa047202.43029894
9Morphine addiction_Homo sapiens_hsa050322.41490719
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.32400035
11Amphetamine addiction_Homo sapiens_hsa050312.29253854
12Insulin secretion_Homo sapiens_hsa049112.25255858
13Dopaminergic synapse_Homo sapiens_hsa047282.11153555
14Salivary secretion_Homo sapiens_hsa049702.06458322
15Taste transduction_Homo sapiens_hsa047421.96708617
16Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.94003161
17Cholinergic synapse_Homo sapiens_hsa047251.90574039
18Gastric acid secretion_Homo sapiens_hsa049711.88919211
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.78569100
20ECM-receptor interaction_Homo sapiens_hsa045121.76988259
21Serotonergic synapse_Homo sapiens_hsa047261.65126260
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.63848118
23Cocaine addiction_Homo sapiens_hsa050301.59399747
24Long-term depression_Homo sapiens_hsa047301.57699852
25Collecting duct acid secretion_Homo sapiens_hsa049661.55777986
26Renin secretion_Homo sapiens_hsa049241.50829612
27Oxytocin signaling pathway_Homo sapiens_hsa049211.45205461
28Calcium signaling pathway_Homo sapiens_hsa040201.40403791
29GnRH signaling pathway_Homo sapiens_hsa049121.33958200
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.31984834
31Type II diabetes mellitus_Homo sapiens_hsa049301.29251727
32Focal adhesion_Homo sapiens_hsa045101.28983936
33Gap junction_Homo sapiens_hsa045401.28646845
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.28503359
35Vibrio cholerae infection_Homo sapiens_hsa051101.24865824
36cAMP signaling pathway_Homo sapiens_hsa040241.22406474
37Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.16819036
38Estrogen signaling pathway_Homo sapiens_hsa049151.15440689
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.13995849
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12328101
41Axon guidance_Homo sapiens_hsa043601.07988173
42Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.04551620
43Melanogenesis_Homo sapiens_hsa049161.03979955
44Glioma_Homo sapiens_hsa052141.01908209
45Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.01835822
46Protein digestion and absorption_Homo sapiens_hsa049741.01034530
47ErbB signaling pathway_Homo sapiens_hsa040121.00948936
48Cardiac muscle contraction_Homo sapiens_hsa042601.00129437
49Nitrogen metabolism_Homo sapiens_hsa009100.96557976
50Vitamin B6 metabolism_Homo sapiens_hsa007500.96090248
51cGMP-PKG signaling pathway_Homo sapiens_hsa040220.96089609
52Dorso-ventral axis formation_Homo sapiens_hsa043200.94300583
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.92331324
54Pancreatic secretion_Homo sapiens_hsa049720.90492099
55Amoebiasis_Homo sapiens_hsa051460.89428348
56Proteoglycans in cancer_Homo sapiens_hsa052050.87252204
57Thyroid hormone synthesis_Homo sapiens_hsa049180.87187748
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.86457791
59Phototransduction_Homo sapiens_hsa047440.82849559
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81641637
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.80588852
62Hippo signaling pathway_Homo sapiens_hsa043900.80524677
63Oocyte meiosis_Homo sapiens_hsa041140.80364849
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77789589
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.76759521
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.75856294
67Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75230442
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73690522
69Adherens junction_Homo sapiens_hsa045200.71088697
70Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70987441
71Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70227471
72Neurotrophin signaling pathway_Homo sapiens_hsa047220.68059443
73MAPK signaling pathway_Homo sapiens_hsa040100.68051580
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65113336
75Type I diabetes mellitus_Homo sapiens_hsa049400.63658239
76Choline metabolism in cancer_Homo sapiens_hsa052310.63241942
77Hedgehog signaling pathway_Homo sapiens_hsa043400.63119709
78Dilated cardiomyopathy_Homo sapiens_hsa054140.62958675
79Ras signaling pathway_Homo sapiens_hsa040140.61303471
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60477149
81Glycosaminoglycan degradation_Homo sapiens_hsa005310.58335951
82PI3K-Akt signaling pathway_Homo sapiens_hsa041510.58059655
83Glucagon signaling pathway_Homo sapiens_hsa049220.57606042
84Tight junction_Homo sapiens_hsa045300.57102800
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56347581
86Alcoholism_Homo sapiens_hsa050340.55940399
87Melanoma_Homo sapiens_hsa052180.55699765
88Inositol phosphate metabolism_Homo sapiens_hsa005620.53835956
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.52652567
90Endocytosis_Homo sapiens_hsa041440.52643238
91Bile secretion_Homo sapiens_hsa049760.52106856
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50536381
93Alzheimers disease_Homo sapiens_hsa050100.49805304
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49771447
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.48745498
96Prion diseases_Homo sapiens_hsa050200.48014142
97Rap1 signaling pathway_Homo sapiens_hsa040150.47777109
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46859575
99VEGF signaling pathway_Homo sapiens_hsa043700.46453424
100Insulin signaling pathway_Homo sapiens_hsa049100.44878576
101Ovarian steroidogenesis_Homo sapiens_hsa049130.44641370
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44610609
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43011676
104Wnt signaling pathway_Homo sapiens_hsa043100.41821319
105Endometrial cancer_Homo sapiens_hsa052130.41646653
106mTOR signaling pathway_Homo sapiens_hsa041500.41261783
107Circadian rhythm_Homo sapiens_hsa047100.40525901
108Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40070190
109Renal cell carcinoma_Homo sapiens_hsa052110.40058616
110AMPK signaling pathway_Homo sapiens_hsa041520.39153209
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38944595
112Pathways in cancer_Homo sapiens_hsa052000.35504140
113Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32981032
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32776601
115Oxidative phosphorylation_Homo sapiens_hsa001900.31093204
116Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30201443
117Chemokine signaling pathway_Homo sapiens_hsa040620.28880618
118Non-small cell lung cancer_Homo sapiens_hsa052230.28498108
119Glycerophospholipid metabolism_Homo sapiens_hsa005640.27503896
120Prolactin signaling pathway_Homo sapiens_hsa049170.24122762
121Parkinsons disease_Homo sapiens_hsa050120.23123197

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »