SPRR1A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of potassium ion transmembrane transporter activity (GO:1901018)8.58755267
2cellular response to ATP (GO:0071318)8.44109568
3detection of bacterium (GO:0016045)8.30547044
4intermediate filament organization (GO:0045109)8.18864836
5regulation of hair follicle development (GO:0051797)8.04656319
6regulation of glucocorticoid metabolic process (GO:0031943)7.95835130
7lipoxygenase pathway (GO:0019372)7.72364240
8establishment of skin barrier (GO:0061436)7.72166736
9detection of other organism (GO:0098543)7.64320767
10regulation of water loss via skin (GO:0033561)7.06682353
11* peptide cross-linking (GO:0018149)6.93987708
12hemidesmosome assembly (GO:0031581)6.79161587
13linoleic acid metabolic process (GO:0043651)6.75282303
14regulation of glucocorticoid secretion (GO:2000849)6.69938360
15regulation of natural killer cell differentiation (GO:0032823)6.44922320
16* keratinocyte differentiation (GO:0030216)6.33763737
17bundle of His cell to Purkinje myocyte communication (GO:0086069)6.13521528
18positive regulation of steroid hormone secretion (GO:2000833)6.02691795
19chemosensory behavior (GO:0007635)6.01333614
20regulation of hair cycle (GO:0042634)5.77400158
21regulation of corticosteroid hormone secretion (GO:2000846)5.70136400
22negative regulation of interferon-gamma production (GO:0032689)5.66529958
23sequestering of metal ion (GO:0051238)5.59351279
24gap junction assembly (GO:0016264)5.52334447
25intermediate filament cytoskeleton organization (GO:0045104)5.50722830
26intermediate filament-based process (GO:0045103)5.34872059
27* epidermis development (GO:0008544)5.21684025
28positive regulation of potassium ion transmembrane transport (GO:1901381)5.06163462
29regulation of cell maturation (GO:1903429)5.05812526
30skin morphogenesis (GO:0043589)5.01821783
31positive regulation of epidermis development (GO:0045684)4.95964697
32virion attachment to host cell (GO:0019062)4.87719061
33adhesion of symbiont to host cell (GO:0044650)4.87719061
34multicellular organismal water homeostasis (GO:0050891)4.80632792
35* epidermal cell differentiation (GO:0009913)4.80371580
36phosphatidylethanolamine acyl-chain remodeling (GO:0036152)4.61868513
37regulation of T cell chemotaxis (GO:0010819)4.52034472
38positive regulation of T cell chemotaxis (GO:0010820)4.52034472
39detection of external biotic stimulus (GO:0098581)4.51898708
40negative regulation of interleukin-17 production (GO:0032700)4.51155506
41establishment of planar polarity (GO:0001736)4.37066880
42establishment of tissue polarity (GO:0007164)4.37066880
43phosphatidylglycerol acyl-chain remodeling (GO:0036148)4.34952320
44regulation of monocyte chemotaxis (GO:0090025)4.30566659
45ectoderm development (GO:0007398)4.15307952
46water homeostasis (GO:0030104)4.14934144
47phosphatidylcholine acyl-chain remodeling (GO:0036151)4.08641487
48transepithelial transport (GO:0070633)4.06420111
49response to ATP (GO:0033198)4.00250668
50adhesion of symbiont to host (GO:0044406)3.98737072
51surfactant homeostasis (GO:0043129)3.94895298
52drinking behavior (GO:0042756)3.89857657
53detection of biotic stimulus (GO:0009595)3.86489672
54regulation of steroid hormone secretion (GO:2000831)3.81184075
55hair follicle morphogenesis (GO:0031069)3.74402558
56regulation of endothelial cell chemotaxis (GO:2001026)3.73486166
57response to phenylpropanoid (GO:0080184)3.62578545
58urinary tract smooth muscle contraction (GO:0014848)3.61175987
59eyelid development in camera-type eye (GO:0061029)3.59621111
60ceramide biosynthetic process (GO:0046513)3.56086170
61phosphatidylserine metabolic process (GO:0006658)3.54792999
62regulation of epidermal cell differentiation (GO:0045604)3.50005000
63negative regulation of cell size (GO:0045792)3.49935564
64citrulline biosynthetic process (GO:0019240)3.49164651
65positive regulation of granulocyte chemotaxis (GO:0071624)3.42468909
66keratinocyte proliferation (GO:0043616)3.42330464
67* epithelial cell differentiation (GO:0030855)3.38796750
68positive regulation of potassium ion transport (GO:0043268)3.36879703
69regulation of potassium ion transmembrane transporter activity (GO:1901016)3.35136747
70planar cell polarity pathway involved in neural tube closure (GO:0090179)3.33891987
71regulation of epidermis development (GO:0045682)3.29046038
72chemical homeostasis within a tissue (GO:0048875)3.28164116
73positive regulation of epidermal cell differentiation (GO:0045606)3.26034571
74peristalsis (GO:0030432)3.25299191
75cAMP-mediated signaling (GO:0019933)3.24077319
76regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.19825285
77fatty acid elongation (GO:0030497)3.19259772
78regulation of natural killer cell activation (GO:0032814)3.18968530
79negative regulation of cell fate specification (GO:0009996)3.06241887
80hair cell differentiation (GO:0035315)3.05517524
81long-chain fatty acid biosynthetic process (GO:0042759)3.04719316
82negative regulation of digestive system process (GO:0060457)3.03308752
83defense response to fungus (GO:0050832)3.01305935
84regulation of T cell migration (GO:2000404)2.98327162
85regulation of endocrine process (GO:0044060)2.97221319
86regulation of neuron projection regeneration (GO:0070570)2.94990616
87regulation of axon regeneration (GO:0048679)2.94990616
88response to UV-B (GO:0010224)2.93179577
89positive regulation of vascular permeability (GO:0043117)2.92369047
90alditol phosphate metabolic process (GO:0052646)2.89515718
91positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.81568588
92cytoskeletal anchoring at plasma membrane (GO:0007016)2.81153465
93regulation of ruffle assembly (GO:1900027)2.80328155
94keratinocyte development (GO:0003334)2.80005058
95negative regulation of keratinocyte proliferation (GO:0010839)2.79701294
96ventricular cardiac muscle cell action potential (GO:0086005)2.78550467
97plasma membrane repair (GO:0001778)2.77432829
98atrioventricular valve morphogenesis (GO:0003181)2.74945867
99positive regulation of cation channel activity (GO:2001259)2.74724434
100phospholipid catabolic process (GO:0009395)2.71278393
101regulation of lymphocyte chemotaxis (GO:1901623)2.70626113
102membrane budding (GO:0006900)2.68690685
103epithelial cell-cell adhesion (GO:0090136)2.67230903
104antimicrobial humoral response (GO:0019730)2.66687183
105sphingoid metabolic process (GO:0046519)2.61381713
106hair cycle process (GO:0022405)2.60928689
107molting cycle process (GO:0022404)2.60928689
108regulation of interleukin-17 production (GO:0032660)2.60259019
109regulation of keratinocyte differentiation (GO:0045616)2.59986853
110regulation of hormone metabolic process (GO:0032350)2.59109936
111apical protein localization (GO:0045176)2.58278301
112phosphatidylinositol acyl-chain remodeling (GO:0036149)2.56878088
113defense response to Gram-negative bacterium (GO:0050829)2.55396629
114regulation of keratinocyte proliferation (GO:0010837)2.54179226
115cell-substrate junction assembly (GO:0007044)2.54112941
116regulation of potassium ion transmembrane transport (GO:1901379)2.53959105
117polarized epithelial cell differentiation (GO:0030859)2.53925133
118cell communication involved in cardiac conduction (GO:0086065)2.51168286
119leukocyte aggregation (GO:0070486)2.50682915
120* epithelium development (GO:0060429)2.45083936
121complement activation, classical pathway (GO:0006958)2.44520639
122cyclic-nucleotide-mediated signaling (GO:0019935)2.44441739
123regulation of heart rate by cardiac conduction (GO:0086091)2.43349915
124positive regulation of T cell migration (GO:2000406)2.43137911
125L-serine transport (GO:0015825)2.42675026
126positive regulation of calcium ion import (GO:0090280)2.42043513
127sphingosine metabolic process (GO:0006670)2.41820231
128sympathetic nervous system development (GO:0048485)2.41515034
129regulation of cardioblast differentiation (GO:0051890)2.40442112
130skin development (GO:0043588)2.39830916
131phosphatidylglycerol metabolic process (GO:0046471)2.39149215
132phosphatidylserine acyl-chain remodeling (GO:0036150)2.35211753
133negative regulation of necrotic cell death (GO:0060547)2.33248628
134negative regulation of lymphocyte differentiation (GO:0045620)2.30553337
135purinergic nucleotide receptor signaling pathway (GO:0035590)2.29996947
136phospholipid efflux (GO:0033700)2.28745300
137regulation of granulocyte chemotaxis (GO:0071622)2.27957060
138one-carbon compound transport (GO:0019755)2.27263878
139primary alcohol catabolic process (GO:0034310)2.26881159
140diol metabolic process (GO:0034311)2.26822789
141cell wall macromolecule metabolic process (GO:0044036)2.26484859
142cell wall macromolecule catabolic process (GO:0016998)2.26484859
143citrulline metabolic process (GO:0000052)2.25287753
144long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.25024175
145activation of protein kinase A activity (GO:0034199)2.22654011
146negative regulation of peptidase activity (GO:0010466)2.22251859
147insulin secretion (GO:0030073)2.22222946
148negative regulation of endopeptidase activity (GO:0010951)2.22125632
149cytidine deamination (GO:0009972)2.21213870
150cytidine metabolic process (GO:0046087)2.21213870
151cytidine catabolic process (GO:0006216)2.21213870
152sphingolipid biosynthetic process (GO:0030148)2.20409715
153complement activation (GO:0006956)2.19756896
154phosphatidic acid metabolic process (GO:0046473)2.19728064
155phosphatidic acid biosynthetic process (GO:0006654)2.19728064
156positive regulation of monocyte chemotaxis (GO:0090026)2.18959861
157chronic inflammatory response (GO:0002544)2.17599634
158serine transport (GO:0032329)2.11236983
159molting cycle (GO:0042303)17.2607939
160hair cycle (GO:0042633)17.2607939
161* keratinization (GO:0031424)12.2088504
162desmosome organization (GO:0002934)11.5605173
163positive regulation of hair cycle (GO:0042635)10.3926129
164positive regulation of hair follicle development (GO:0051798)10.3926129

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.69729336
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.97021737
3* P63_26484246_Chip-Seq_KERATINOCYTES_Human2.78599804
4TRIM28_21343339_ChIP-Seq_HEK293_Human2.61975116
5SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.55042988
6CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.18353508
7SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.16573716
8SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.16573716
9ESR2_21235772_ChIP-Seq_MCF-7_Human2.16068863
10ESR1_21235772_ChIP-Seq_MCF-7_Human2.14307979
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.05961267
12ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.05150059
13TP63_17297297_ChIP-ChIP_HaCaT_Human12.6614513
14* GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.91321122
15SOX9_24532713_ChIP-Seq_HFSC_Mouse1.89432975
16PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.84626063
17FOXO3_23340844_ChIP-Seq_DLD1_Human1.82230609
18* SOX2_20726797_ChIP-Seq_SW620_Human1.77376202
19ATF3_27146783_Chip-Seq_COLON_Human1.73689968
20GATA6_21074721_ChIP-Seq_CACO-2_Human1.71042068
21NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.67695729
22RACK7_27058665_Chip-Seq_MCF-7_Human1.62589230
23STAT6_21828071_ChIP-Seq_BEAS2B_Human1.59122748
24ZNF263_19887448_ChIP-Seq_K562_Human1.54572834
25PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.50514249
26CLOCK_20551151_ChIP-Seq_293T_Human1.49908151
27JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.49817111
28RXR_22108803_ChIP-Seq_LS180_Human1.45355147
29JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.42012496
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.39215397
31EGR1_19032775_ChIP-ChIP_M12_Human1.39031723
32ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.38958966
33KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.38557125
34CTCF_27219007_Chip-Seq_Bcells_Human1.38069394
35HIF1A_21447827_ChIP-Seq_MCF-7_Human1.31903856
36KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.31262032
37CTCF_20526341_ChIP-Seq_ESCs_Human1.30959479
38STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.29213115
39LXR_22292898_ChIP-Seq_THP-1_Human1.27654130
40DNAJC2_21179169_ChIP-ChIP_NT2_Human1.25144868
41CJUN_26792858_Chip-Seq_BT549_Human1.24895584
42CDX2_19796622_ChIP-Seq_MESCs_Mouse1.24494522
43ZNF217_24962896_ChIP-Seq_MCF-7_Human1.24239502
44TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22950665
45* TP63_22573176_ChIP-Seq_HFKS_Human1.21827810
46RUNX1_27514584_Chip-Seq_MCF-7_Human1.19894092
47VDR_22108803_ChIP-Seq_LS180_Human1.19266230
48GATA3_24758297_ChIP-Seq_MCF-7_Human1.16969413
49KLF5_25053715_ChIP-Seq_YYC3_Human1.16047323
50TP63_23658742_ChIP-Seq_EP156T_Human1.15277050
51UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.14624481
52BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.13409184
53P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.11228620
54ELK3_25401928_ChIP-Seq_HUVEC_Human1.09907142
55ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.08908985
56ERG_21242973_ChIP-ChIP_JURKAT_Human1.06846715
57SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.05608379
58TP53_20018659_ChIP-ChIP_R1E_Mouse1.05569231
59TP53_18474530_ChIP-ChIP_U2OS_Human1.01920908
60ESR1_20079471_ChIP-ChIP_T-47D_Human1.01789631
61SUZ12_27294783_Chip-Seq_ESCs_Mouse1.01479431
62AR_21572438_ChIP-Seq_LNCaP_Human1.01288041
63CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.01259692
64SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.00731877
65GATA4_25053715_ChIP-Seq_YYC3_Human0.99717017
66BCL6_27268052_Chip-Seq_Bcells_Human0.99011066
67VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.98772094
68GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.98078810
69BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97907844
70BCOR_27268052_Chip-Seq_Bcells_Human0.97475214
71JARID2_20075857_ChIP-Seq_MESCs_Mouse0.97389150
72UBF1/2_26484160_Chip-Seq_HMECs_Human0.96922077
73CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.96852581
74P300_27058665_Chip-Seq_ZR-75-30cells_Human0.96179325
75RBPJ_21746931_ChIP-Seq_IB4_Human0.96139306
76AHR_22903824_ChIP-Seq_MCF-7_Human0.95843279
77CSB_26484114_Chip-Seq_FIBROBLAST_Human0.95400505
78P53_21459846_ChIP-Seq_SAOS-2_Human0.94762639
79ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94431859
80RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.93571454
81SA1_27219007_Chip-Seq_ERYTHROID_Human0.93487250
82ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.93439665
83SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.93223585
84GATA6_25053715_ChIP-Seq_YYC3_Human0.92259251
85KDM2B_26808549_Chip-Seq_K562_Human0.92236195
86* E2F1_20622854_ChIP-Seq_HELA_Human0.92068616
87PPAR_26484153_Chip-Seq_NCI-H1993_Human0.90145189
88ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.90110735
89HTT_18923047_ChIP-ChIP_STHdh_Human0.89852059
90SA1_27219007_Chip-Seq_Bcells_Human0.89492553
91TCF4_18268006_ChIP-ChIP_LS174T_Human0.88210626
92SOX2_27498859_Chip-Seq_STOMACH_Mouse0.86488249
93SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.86340063
94PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.86017733
95* ERG_20517297_ChIP-Seq_VCAP_Human0.85725295
96* NANOG_20526341_ChIP-Seq_ESCs_Human0.85567569
97* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.85496791
98CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.85493054
99* MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.82863543
100YY1_22570637_ChIP-Seq_MALME-3M_Human0.82506837
101SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.81831493
102CEBPB_22108803_ChIP-Seq_LS180_Human0.81786701
103SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.81726742
104SMC4_20622854_ChIP-Seq_HELA_Human0.81287592
105RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.81112867
106TAF2_19829295_ChIP-Seq_ESCs_Human0.81066515
107EZH2_27294783_Chip-Seq_ESCs_Mouse0.80264509
108P300_27268052_Chip-Seq_Bcells_Human0.78573308
109PPARA_22158963_ChIP-Seq_LIVER_Mouse0.78271440
110KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.77781334
111HNFA_21074721_ChIP-Seq_CACO-2_Human0.76852412
112GATA2_21666600_ChIP-Seq_HMVEC_Human0.76236501
113FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.75120717
114CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.74612810
115TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.74085223
116RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.73876755
117P68_20966046_ChIP-Seq_HELA_Human0.72905751
118SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.72775220
119SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.72595604
120THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.71632502
121CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.71343696
122RNF2_18974828_ChIP-Seq_MESCs_Mouse0.71234611
123EZH2_18974828_ChIP-Seq_MESCs_Mouse0.71234611
124PHF8_20622854_ChIP-Seq_HELA_Human0.71182831
125GATA1_19941826_ChIP-Seq_K562_Human0.69619738
126KDM2B_26808549_Chip-Seq_DND41_Human0.68449794
127GATA2_19941826_ChIP-Seq_K562_Human0.67997811
128FOXM1_26456572_ChIP-Seq_MCF-7_Human0.67421347
129JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.66594418

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier6.23885973
2MP0000579_abnormal_nail_morphology5.80582307
3MP0004858_abnormal_nervous_system5.27281707
4MP0002163_abnormal_gland_morphology4.72002049
5MP0005275_abnormal_skin_tensile4.60671558
6MP0010234_abnormal_vibrissa_follicle4.54688262
7MP0005501_abnormal_skin_physiology3.98622065
8MP0000427_abnormal_hair_cycle3.60030507
9MP0002098_abnormal_vibrissa_morphology3.55305418
10MP0001986_abnormal_taste_sensitivity3.49642038
11MP0000647_abnormal_sebaceous_gland3.41451161
12MP0003878_abnormal_ear_physiology2.99403300
13MP0005377_hearing/vestibular/ear_phenot2.99403300
14MP0003705_abnormal_hypodermis_morpholog2.98792250
15MP0003941_abnormal_skin_development2.92627048
16MP0000383_abnormal_hair_follicle2.88608356
17MP0005379_endocrine/exocrine_gland_phen2.87979689
18MP0010771_integument_phenotype2.81724769
19MP0010678_abnormal_skin_adnexa2.81194259
20MP0004043_abnormal_pH_regulation2.72583346
21MP0003453_abnormal_keratinocyte_physiol2.69696704
22MP0002735_abnormal_chemical_nociception2.66284204
23MP0001216_abnormal_epidermal_layer2.66174552
24MP0000377_abnormal_hair_follicle2.61227704
25MP0002254_reproductive_system_inflammat2.57664931
26MP0004381_abnormal_hair_follicle2.44759969
27MP0002060_abnormal_skin_morphology2.37904669
28MP0005646_abnormal_pituitary_gland2.21822625
29MP0000467_abnormal_esophagus_morphology2.11575660
30MP0004947_skin_inflammation2.04451598
31MP0001968_abnormal_touch/_nociception1.91900650
32MP0003566_abnormal_cell_adhesion1.76817660
33MP0000762_abnormal_tongue_morphology1.63197366
34MP0001243_abnormal_dermal_layer1.45063360
35MP0002095_abnormal_skin_pigmentation1.44700849
36MP0000367_abnormal_coat/_hair1.40934039
37MP0002234_abnormal_pharynx_morphology1.32963644
38MP0009931_abnormal_skin_appearance1.29605585
39MP0005647_abnormal_sex_gland1.15233195
40MP0003191_abnormal_cellular_cholesterol1.09122063
41MP0001191_abnormal_skin_condition1.08647015
42MP0009053_abnormal_anal_canal1.05594334
43MP0010352_gastrointestinal_tract_polyps1.00991967
44MP0001188_hyperpigmentation1.00440881
45MP0000627_abnormal_mammary_gland0.98122720
46MP0003329_amyloid_beta_deposits0.97133839
47MP0002733_abnormal_thermal_nociception0.96148815
48MP0001881_abnormal_mammary_gland0.95096699
49MP0005451_abnormal_body_composition0.87955722
50MP0001851_eye_inflammation0.87708832
51MP0005023_abnormal_wound_healing0.83777188
52MP0005165_increased_susceptibility_to0.83132096
53MP0008775_abnormal_heart_ventricle0.79789179
54MP0004484_altered_response_of0.73171898
55MP0004185_abnormal_adipocyte_glucose0.72752403
56MP0008872_abnormal_physiological_respon0.72751662
57MP0005367_renal/urinary_system_phenotyp0.71816259
58MP0000516_abnormal_urinary_system0.71816259
59MP0004264_abnormal_extraembryonic_tissu0.71691951
60MP0000537_abnormal_urethra_morphology0.70929643
61MP0000538_abnormal_urinary_bladder0.70263585
62MP0004272_abnormal_basement_membrane0.69383002
63MP0002877_abnormal_melanocyte_morpholog0.68653795
64MP0001346_abnormal_lacrimal_gland0.68027836
65MP0001340_abnormal_eyelid_morphology0.67001775
66MP0000566_synostosis0.63758396
67MP0005409_darkened_coat_color0.60055422
68MP0008438_abnormal_cutaneous_collagen0.57303993
69MP0008004_abnormal_stomach_pH0.56957446
70MP0000604_amyloidosis0.56620985
71MP0003300_gastrointestinal_ulcer0.56601286
72MP0008873_increased_physiological_sensi0.54729930
73MP0000465_gastrointestinal_hemorrhage0.53477810
74MP0003315_abnormal_perineum_morphology0.51421308
75MP0001485_abnormal_pinna_reflex0.51004944
76MP0003011_delayed_dark_adaptation0.50878069
77MP0000751_myopathy0.49604304
78MP0001756_abnormal_urination0.49039687
79MP0000470_abnormal_stomach_morphology0.49005334
80MP0002734_abnormal_mechanical_nocicepti0.48220679
81MP0005503_abnormal_tendon_morphology0.48036992
82MP0001849_ear_inflammation0.46746806
83MP0002751_abnormal_autonomic_nervous0.46509085
84MP0004270_analgesia0.46372888
85MP0000749_muscle_degeneration0.45896870
86MP0009840_abnormal_foam_cell0.43864861
87MP0002138_abnormal_hepatobiliary_system0.43530760
88MP0000371_diluted_coat_color0.41234439
89MP0003724_increased_susceptibility_to0.40240596
90MP0002970_abnormal_white_adipose0.39885646
91MP0009379_abnormal_foot_pigmentation0.39330894
92MP0001970_abnormal_pain_threshold0.39172712
93MP0002282_abnormal_trachea_morphology0.38126499
94MP0005666_abnormal_adipose_tissue0.36858433
95MP0004145_abnormal_muscle_electrophysio0.36780726
96MP0000678_abnormal_parathyroid_gland0.33671806
97MP0003638_abnormal_response/metabolism_0.33118032
98MP0004782_abnormal_surfactant_physiolog0.32972466
99MP0002009_preneoplasia0.32391772
100MP0010030_abnormal_orbit_morphology0.32320073
101MP0001765_abnormal_ion_homeostasis0.32298015
102MP0001784_abnormal_fluid_regulation0.32236535
103MP0005375_adipose_tissue_phenotype0.32204952
104MP0000685_abnormal_immune_system0.32092702
105MP0002111_abnormal_tail_morphology0.31125329
106MP0003755_abnormal_palate_morphology0.29541768
107MP0001186_pigmentation_phenotype0.28865341
108MP0008789_abnormal_olfactory_epithelium0.28778702
109MP0003950_abnormal_plasma_membrane0.28740653
110MP0005248_abnormal_Harderian_gland0.28734366
111MP0002075_abnormal_coat/hair_pigmentati0.27163203
112MP0008569_lethality_at_weaning0.26699750
113MP0003436_decreased_susceptibility_to0.26528058
114MP0009115_abnormal_fat_cell0.25717251
115MP0004197_abnormal_fetal_growth/weight/0.24998698
116MP0003045_fibrosis0.23956754
117MP0005193_abnormal_anterior_eye0.23791820
118MP0003385_abnormal_body_wall0.23401240
119MP0003763_abnormal_thymus_physiology0.23219609
120MP0010386_abnormal_urinary_bladder0.22066967
121MP0004019_abnormal_vitamin_homeostasis0.21792304
122MP0009333_abnormal_splenocyte_physiolog0.21789542
123MP0002133_abnormal_respiratory_system0.21513028
124MP0005388_respiratory_system_phenotype0.21513028
125MP0005394_taste/olfaction_phenotype0.20017991
126MP0005499_abnormal_olfactory_system0.20017991
127MP0004885_abnormal_endolymph0.19245352
128MP0009780_abnormal_chondrocyte_physiolo0.18404929
129MP0000003_abnormal_adipose_tissue0.17967834
130MP0005448_abnormal_energy_balance0.17966638
131MP0008260_abnormal_autophagy0.17640891
132MP0006054_spinal_hemorrhage0.17503219
133MP0005076_abnormal_cell_differentiation0.15536939
134MP0002177_abnormal_outer_ear0.15230384
135MP0003633_abnormal_nervous_system0.15139609
136MP0001533_abnormal_skeleton_physiology0.13955151
137MP0003828_pulmonary_edema0.11119339
138MP0001958_emphysema0.10208959
139MP0001879_abnormal_lymphatic_vessel0.10066862
140MP0000858_altered_metastatic_potential0.09714914
141MP0002249_abnormal_larynx_morphology0.08007648
142MP0005636_abnormal_mineral_homeostasis0.06889895
143MP0002006_tumorigenesis0.06441436
144MP0005387_immune_system_phenotype0.06225067
145MP0001790_abnormal_immune_system0.06225067

Predicted human phenotypes

RankGene SetZ-score
1Hypotrichosis (HP:0001006)9.41084171
2Abnormality of nail color (HP:0100643)9.07577980
3Woolly hair (HP:0002224)7.84360809
4Right ventricular cardiomyopathy (HP:0011663)6.30048920
5Palmoplantar hyperkeratosis (HP:0000972)6.17639465
6Pili torti (HP:0003777)6.11288356
7Plantar hyperkeratosis (HP:0007556)5.89978220
8Palmar hyperkeratosis (HP:0010765)5.78940703
9Thick nail (HP:0001805)5.70471064
10Nail dystrophy (HP:0008404)5.58038931
11Increased IgE level (HP:0003212)5.56012358
12Onycholysis (HP:0001806)5.15892772
13Fragile nails (HP:0001808)5.09605381
14Alopecia of scalp (HP:0002293)4.99101646
15Abnormality of the axillary hair (HP:0100134)4.89342675
16Abnormality of secondary sexual hair (HP:0009888)4.89342675
17Hyporeflexia of lower limbs (HP:0002600)4.83775016
18Distal lower limb muscle weakness (HP:0009053)4.69757619
19Brittle hair (HP:0002299)4.47935772
20Slow-growing hair (HP:0002217)4.38385465
21Abnormality of hair growth rate (HP:0011363)4.38385465
22Erythema (HP:0010783)4.24715057
23Follicular hyperkeratosis (HP:0007502)4.16469019
24Congenital ichthyosiform erythroderma (HP:0007431)4.15807570
25Milia (HP:0001056)4.04292496
26Parakeratosis (HP:0001036)3.95396007
27Pustule (HP:0200039)3.95164159
28Oral leukoplakia (HP:0002745)3.89986846
29Abnormal blistering of the skin (HP:0008066)3.84754917
30Abnormal hair laboratory examination (HP:0003328)3.83164575
31Ulnar claw (HP:0001178)3.75425858
32Absent eyelashes (HP:0000561)3.73167393
33Erythroderma (HP:0001019)3.52325288
34Absent hair (HP:0002298)3.48050732
35Curly hair (HP:0002212)3.37945147
36Lip pit (HP:0100267)3.32294330
37Natal tooth (HP:0000695)3.26651369
38Abnormality of placental membranes (HP:0011409)3.25854795
39Amniotic constriction ring (HP:0009775)3.25854795
40Sparse eyelashes (HP:0000653)3.17770291
41Advanced eruption of teeth (HP:0006288)3.14382953
42Conjunctival hamartoma (HP:0100780)3.14279562
43Furrowed tongue (HP:0000221)3.04253812
44Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.04175266
45Areflexia of lower limbs (HP:0002522)2.99459866
46Abnormality of the salivary glands (HP:0010286)2.99443215
47Ventricular tachycardia (HP:0004756)2.97178478
48Palmoplantar keratoderma (HP:0000982)2.91924288
49Corneal erosion (HP:0200020)2.82771815
50Dehydration (HP:0001944)2.61160863
51Hypohidrosis (HP:0000966)2.53045818
52Urticaria (HP:0001025)2.52569932
53Ridged nail (HP:0001807)2.48755765
54Ectropion (HP:0000656)2.44454000
55Pruritus (HP:0000989)2.37444370
56Multifactorial inheritance (HP:0001426)2.34442177
57Gangrene (HP:0100758)2.31310544
58Laryngomalacia (HP:0001601)2.26284894
59Atrophic scars (HP:0001075)2.24293728
60Corneal dystrophy (HP:0001131)2.18668432
61Epidermoid cyst (HP:0200040)2.16550722
62Increased connective tissue (HP:0009025)2.16507187
63Fine hair (HP:0002213)2.14855433
64Neck muscle weakness (HP:0000467)2.07538326
65Recurrent corneal erosions (HP:0000495)2.07218932
66Paralysis (HP:0003470)2.06888429
67Anonychia (HP:0001798)2.04388086
68Acanthosis nigricans (HP:0000956)2.04188981
69Abnormal hemoglobin (HP:0011902)2.01271053
70Sepsis (HP:0100806)1.98658987
71Calcaneovalgus deformity (HP:0001848)1.97812436
72Keratoconjunctivitis sicca (HP:0001097)1.97149066
73Ventricular fibrillation (HP:0001663)1.96016868
74Foot dorsiflexor weakness (HP:0009027)1.95975542
75Abnormality of the neuromuscular junction (HP:0003398)1.95055843
76Fatigable weakness (HP:0003473)1.95055843
77Abnormality of the gastric mucosa (HP:0004295)1.89932677
78Villous atrophy (HP:0011473)1.89831641
79Abnormality of small intestinal villus morphology (HP:0011472)1.89831641
80Hamartoma of the eye (HP:0010568)1.89749109
81Dry hair (HP:0011359)1.87595092
82Lack of skin elasticity (HP:0100679)1.86514718
83Achilles tendon contracture (HP:0001771)1.81369320
84Hypoplastic labia majora (HP:0000059)1.79511059
85EMG: neuropathic changes (HP:0003445)1.79108956
86Hyperhidrosis (HP:0000975)1.78922901
87Keratoconjunctivitis (HP:0001096)1.78564063
88Sudden death (HP:0001699)1.75552158
89Recurrent bacterial skin infections (HP:0005406)1.74745425
90Abnormality of the foot musculature (HP:0001436)1.74539990
91Steppage gait (HP:0003376)1.74478478
92Dry skin (HP:0000958)1.73488468
93Fasciculations (HP:0002380)1.71792809
94Deformed tarsal bones (HP:0008119)1.70787741
95Abnormality of the Achilles tendon (HP:0005109)1.69891065
96Difficulty walking (HP:0002355)1.69122225
97Sparse scalp hair (HP:0002209)1.67406256
98Skin ulcer (HP:0200042)1.67317780
99Axonal loss (HP:0003447)1.65499221
100Muscle fiber splitting (HP:0003555)1.64482232
101Abnormality of the labia majora (HP:0012881)1.63093540
102Popliteal pterygium (HP:0009756)1.62896892
103Amelogenesis imperfecta (HP:0000705)1.62497942
104Hypoplastic toenails (HP:0001800)1.60966236
105Hypergammaglobulinemia (HP:0010702)1.59720535
106Type 1 muscle fiber predominance (HP:0003803)1.59577155
107Distal lower limb amyotrophy (HP:0008944)1.59402580
108Autoamputation (HP:0001218)1.58718248
109Increased variability in muscle fiber diameter (HP:0003557)1.57315442
110Papilloma (HP:0012740)1.57075952
111Verrucae (HP:0200043)1.57075952
112Congenital, generalized hypertrichosis (HP:0004540)1.56913910
113Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.56556331
114Eczematoid dermatitis (HP:0000976)1.55972824
115Aplasia cutis congenita (HP:0001057)1.55953045
116Neonatal onset (HP:0003623)1.55305877
117Intention tremor (HP:0002080)1.54373572
118Blepharitis (HP:0000498)1.53025059
119Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.52860741
120Carious teeth (HP:0000670)1.51622055
121Abnormality of skeletal muscle fiber size (HP:0012084)1.51262412
122Preauricular skin tag (HP:0000384)1.49958053
123Muscle fiber inclusion bodies (HP:0100299)1.49383905
124Nemaline bodies (HP:0003798)1.48663138
125Round ear (HP:0100830)1.47373405
126Abnormality of the fingernails (HP:0001231)1.46245596
127Distal arthrogryposis (HP:0005684)1.46236321
128Wrist flexion contracture (HP:0001239)1.46130407
129Fragile skin (HP:0001030)1.45684511
130Upper limb amyotrophy (HP:0009129)1.45536206
131Distal upper limb amyotrophy (HP:0007149)1.45536206
132Abnormality of the calcaneus (HP:0008364)1.45106423
133Melanocytic nevus (HP:0000995)1.44647960
134Selective tooth agenesis (HP:0001592)1.29402639
135Seborrheic dermatitis (HP:0001051)1.28731642
136Segmental peripheral demyelination/remyelination (HP:0003481)1.27236567
137Generalized hyperpigmentation (HP:0007440)1.27026344
138Skin tags (HP:0010609)1.25943540
139Squamous cell carcinoma (HP:0002860)1.24186613
140Xerostomia (HP:0000217)1.21564437
141Oligodontia (HP:0000677)1.21562146
142Hyperactive renin-angiotensin system (HP:0000841)1.21058653
143Everted lower lip vermilion (HP:0000232)1.19266452

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPKAPK38.20802140
2RPS6KB24.24090203
3FER4.01319628
4EPHA23.63890104
5STK242.63386581
6ERN12.56558136
7GRK62.52657517
8PIM22.52094240
9SGK4942.36833816
10SGK2232.36833816
11EPHA32.35800847
12CAMK1D2.33136542
13CAMKK22.30019012
14MAP3K32.21981178
15MST42.09480012
16EPHB22.08848801
17EPHB12.03220466
18MST1R1.91055706
19MAP3K21.81764412
20TTN1.80637332
21LATS21.60508374
22FGFR41.55418804
23LIMK11.45054493
24MAP3K91.38599380
25TRIB31.35384200
26CAMK1G1.35040130
27TESK11.31648331
28IRAK11.31465673
29BLK1.30401521
30PIK3CG1.29159233
31PTK21.19193925
32MAP2K11.15111196
33LRRK21.14341787
34PAK31.11212758
35TAOK11.09732412
36PTK61.07564193
37TRPM71.06919263
38MARK21.05286009
39FGR1.04182384
40PRKCE1.03844060
41BCR1.03759555
42WNK10.99292879
43MAP3K10.97784393
44MAP3K60.97756168
45KSR20.96940160
46JAK30.96822097
47CAMKK10.94338612
48LATS10.93534760
49RIPK10.92826570
50MAPK70.90752377
51MAPKAPK20.90678009
52NTRK10.89597128
53MAP3K110.84316246
54TYRO30.84013379
55MATK0.82454948
56IKBKB0.82037747
57PRKD20.80527589
58RET0.79482588
59IRAK30.78317932
60MET0.77617614
61DYRK1B0.73307485
62PRKD10.71921633
63ERBB30.71677761
64FGFR30.71511714
65MAP2K20.66926027
66CDK60.66270492
67PRKCI0.64368231
68SIK10.64099069
69CDC42BPA0.64051066
70NME10.63064392
71MINK10.62755052
72PBK0.62572151
73ZAP700.60431646
74MAP2K40.59652334
75MAP2K60.58809125
76ARAF0.57530644
77TYK20.55448742
78PAK20.55007054
79STK100.53563552
80MYLK0.53407707
81ADRBK10.53246901
82ERBB20.53134549
83SGK10.52174651
84DDR20.51679952
85STK380.51177802
86PKN20.50808399
87FGFR10.50641487
88IKBKE0.50522018
89FLT30.50496421
90CDK120.49224694
91TXK0.48105842
92NTRK30.47441319
93PDGFRA0.46055872
94MAP3K50.45471463
95HCK0.44451443
96FRK0.43574811
97SRC0.42947761
98HIPK20.41775362
99EEF2K0.40832183
100MAP2K30.40442790
101TGFBR10.39404746
102LMTK20.38703761
103SIK30.38487162
104SGK30.37977052
105CSK0.37661216
106STK30.37581494
107BMPR1B0.37025763
108ABL20.36533564
109MAPK40.36366165
110IRAK40.35746408
111MAP3K130.34875723
112PAK60.33048556
113PDGFRB0.32014887
114MAP3K70.31634579
115ERBB40.31024106
116MTOR0.30991160
117IRAK20.30654432
118NLK0.30497668
119TBK10.30471056
120TAOK30.29515255
121GSK3A0.29481309
122PRKAA20.28493454
123NEK10.28257502
124SCYL20.28178666
125RPS6KB10.27914884
126BMX0.27611891
127RIPK40.27429765
128RPS6KA10.27056383
129JAK20.26645207
130CAMK2G0.25989956
131CDK50.25777203
132DYRK20.25047777
133PRKCD0.24098402
134FYN0.24085800
135DAPK30.23466776
136RPS6KA40.23375507
137JAK10.23223045
138TGFBR20.22243694
139GRK50.21690776
140MAP3K120.21623501
141SGK20.21470411
142ALK0.20052422
143DMPK0.19260054
144PHKG10.19172507
145PHKG20.19172507

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.74576254
2Pathogenic Escherichia coli infection_Homo sapiens_hsa051303.05465707
3alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.40370124
4Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.32856233
5Linoleic acid metabolism_Homo sapiens_hsa005912.32670225
6VEGF signaling pathway_Homo sapiens_hsa043702.01613280
7Cyanoamino acid metabolism_Homo sapiens_hsa004602.01119210
8Steroid biosynthesis_Homo sapiens_hsa001001.95460205
9Ovarian steroidogenesis_Homo sapiens_hsa049131.94721615
10Fatty acid elongation_Homo sapiens_hsa000621.89247419
11Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.76966466
12Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.72266109
13Bladder cancer_Homo sapiens_hsa052191.70729209
14Long-term depression_Homo sapiens_hsa047301.66322685
15ECM-receptor interaction_Homo sapiens_hsa045121.59781906
16Fat digestion and absorption_Homo sapiens_hsa049751.56181133
17Phenylalanine metabolism_Homo sapiens_hsa003601.49154770
18Proteoglycans in cancer_Homo sapiens_hsa052051.44872670
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.42143293
20Serotonergic synapse_Homo sapiens_hsa047261.41951710
21Adherens junction_Homo sapiens_hsa045201.36544269
22Ether lipid metabolism_Homo sapiens_hsa005651.35453132
23Thyroid cancer_Homo sapiens_hsa052161.30636326
24Tight junction_Homo sapiens_hsa045301.30109311
25Arachidonic acid metabolism_Homo sapiens_hsa005901.29983464
26Phototransduction_Homo sapiens_hsa047441.28197619
27Sphingolipid metabolism_Homo sapiens_hsa006001.24220932
28Amoebiasis_Homo sapiens_hsa051461.21774360
29Synaptic vesicle cycle_Homo sapiens_hsa047211.20299191
30Choline metabolism in cancer_Homo sapiens_hsa052311.19695354
31Circadian rhythm_Homo sapiens_hsa047101.19280363
32Salmonella infection_Homo sapiens_hsa051321.15792930
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.14844839
34Glioma_Homo sapiens_hsa052141.14316562
35GnRH signaling pathway_Homo sapiens_hsa049121.10106983
36Sphingolipid signaling pathway_Homo sapiens_hsa040711.08049462
37Axon guidance_Homo sapiens_hsa043601.06881545
38Histidine metabolism_Homo sapiens_hsa003401.03889679
39Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.03690507
40Hippo signaling pathway_Homo sapiens_hsa043901.02689646
41Phagosome_Homo sapiens_hsa041451.01155977
42Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.00020280
43Leukocyte transendothelial migration_Homo sapiens_hsa046700.98741123
44Pertussis_Homo sapiens_hsa051330.97632232
45Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.97526503
46Shigellosis_Homo sapiens_hsa051310.96687557
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.96667771
48Vibrio cholerae infection_Homo sapiens_hsa051100.94997193
49Melanogenesis_Homo sapiens_hsa049160.92863208
50Acute myeloid leukemia_Homo sapiens_hsa052210.92131990
51Gap junction_Homo sapiens_hsa045400.91878062
52Basal cell carcinoma_Homo sapiens_hsa052170.90638379
53Platelet activation_Homo sapiens_hsa046110.90293504
54ErbB signaling pathway_Homo sapiens_hsa040120.89813928
55Steroid hormone biosynthesis_Homo sapiens_hsa001400.88724890
56Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.87964701
57Dilated cardiomyopathy_Homo sapiens_hsa054140.87900506
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.87597568
59Dorso-ventral axis formation_Homo sapiens_hsa043200.85201258
60Focal adhesion_Homo sapiens_hsa045100.80825129
61Collecting duct acid secretion_Homo sapiens_hsa049660.80168863
62Hepatitis C_Homo sapiens_hsa051600.77865947
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.76780324
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.74777631
65Endocytosis_Homo sapiens_hsa041440.74711646
66Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.73613138
67PPAR signaling pathway_Homo sapiens_hsa033200.73202119
68Chemical carcinogenesis_Homo sapiens_hsa052040.73079338
69Gastric acid secretion_Homo sapiens_hsa049710.72527190
70Toxoplasmosis_Homo sapiens_hsa051450.70001470
71Mineral absorption_Homo sapiens_hsa049780.68594867
72Oxytocin signaling pathway_Homo sapiens_hsa049210.67857336
73AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.67668857
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.66453474
75Taste transduction_Homo sapiens_hsa047420.66251179
76Renin secretion_Homo sapiens_hsa049240.65970088
77Prolactin signaling pathway_Homo sapiens_hsa049170.64693709
78Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64475338
79Ras signaling pathway_Homo sapiens_hsa040140.64266075
80p53 signaling pathway_Homo sapiens_hsa041150.63395565
81Insulin signaling pathway_Homo sapiens_hsa049100.63336378
82Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.63128139
83Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.62854836
84Endometrial cancer_Homo sapiens_hsa052130.62841312
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.62722773
86beta-Alanine metabolism_Homo sapiens_hsa004100.62079201
87Estrogen signaling pathway_Homo sapiens_hsa049150.61241737
88Pancreatic secretion_Homo sapiens_hsa049720.61131184
89Caffeine metabolism_Homo sapiens_hsa002320.61067929
90Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60446848
91Salivary secretion_Homo sapiens_hsa049700.60006615
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.59394326
93Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59172992
94Apoptosis_Homo sapiens_hsa042100.58214631
95MicroRNAs in cancer_Homo sapiens_hsa052060.57019437
96Pancreatic cancer_Homo sapiens_hsa052120.56818095
97Fructose and mannose metabolism_Homo sapiens_hsa000510.56453581
98Renin-angiotensin system_Homo sapiens_hsa046140.56310374
99Malaria_Homo sapiens_hsa051440.56173104
100Arginine biosynthesis_Homo sapiens_hsa002200.54998358
101Lysosome_Homo sapiens_hsa041420.53816930
102Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.52948601
103Rap1 signaling pathway_Homo sapiens_hsa040150.52910724
104Insulin resistance_Homo sapiens_hsa049310.52819919
105Tyrosine metabolism_Homo sapiens_hsa003500.52446016
106Adipocytokine signaling pathway_Homo sapiens_hsa049200.51133022
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.50856808
108Olfactory transduction_Homo sapiens_hsa047400.50732297
109Chronic myeloid leukemia_Homo sapiens_hsa052200.50118599
110Long-term potentiation_Homo sapiens_hsa047200.50071978
111Glutamatergic synapse_Homo sapiens_hsa047240.49828397
112Influenza A_Homo sapiens_hsa051640.48705032
113Renal cell carcinoma_Homo sapiens_hsa052110.48371294
114Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48016649
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.47988596
116Hedgehog signaling pathway_Homo sapiens_hsa043400.47747650
117Melanoma_Homo sapiens_hsa052180.47576893
118MAPK signaling pathway_Homo sapiens_hsa040100.46327416
119HIF-1 signaling pathway_Homo sapiens_hsa040660.46291042
120ABC transporters_Homo sapiens_hsa020100.45849057
121Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45389368
122Retinol metabolism_Homo sapiens_hsa008300.44800886
123Tuberculosis_Homo sapiens_hsa051520.43993159
124Dopaminergic synapse_Homo sapiens_hsa047280.43485266
125Staphylococcus aureus infection_Homo sapiens_hsa051500.43463591
126Notch signaling pathway_Homo sapiens_hsa043300.41885960
127Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40633412
128Galactose metabolism_Homo sapiens_hsa000520.40463688
129Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.35531225
130Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.30482801
131NOD-like receptor signaling pathway_Homo sapiens_hsa046210.29831785
132TNF signaling pathway_Homo sapiens_hsa046680.28214905
133Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.25956623
134RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.23134529

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »